TWAS hub - RAB5C

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2120	0.0450	6.9e-14	0.177	0.130	0.164	0.175	0.172	4.7e-21	1.6e-15	1.9e-19	8.1e-21	1.9e-20
2	GTEx	Adipose Subcutaneous	0.1860	0.0510	1.2e-08	0.165	NA	0.165	NA	0.165	1.8e-13	NA	2.0e-13	NA	2.1e-13
3	GTEx	Adipose Visceral Omentum	0.1890	0.0840	6.8e-03	0.019	NA	0.000	NA	0.018	3.3e-02	NA	3.1e-01	NA	3.7e-02
4	GTEx	Breast Mammary Tissue	0.1480	0.0490	5.8e-05	0.145	NA	0.089	NA	0.103	6.9e-08	NA	2.5e-05	NA	6.2e-06
5	GTEx	Breast Mammary Tissue (Female)	0.1391	0.0595	6.8e-03	0.032	NA	0.042	NA	0.027	3.9e-02	NA	2.1e-02	NA	5.4e-02
6	GTEx	Esophagus Muscularis	0.2000	0.0570	7.3e-07	0.115	NA	0.105	NA	0.111	1.9e-07	NA	6.4e-07	NA	3.1e-07
7	GTEx	Lung	0.1494	0.0433	6.8e-07	0.128	NA	0.101	NA	0.112	5.3e-10	NA	3.8e-08	NA	6.9e-09
8	GTEx	Muscle Skeletal	0.1049	0.0396	3.2e-04	0.066	NA	0.041	NA	0.055	4.8e-07	NA	6.0e-05	NA	3.8e-06
9	GTEx	Nerve Tibial	0.1402	0.0428	3.1e-05	0.079	NA	0.057	NA	0.070	3.3e-06	NA	6.9e-05	NA	1.1e-05
10	GTEx	Pancreas	0.1400	0.0580	3.5e-03	0.127	NA	0.064	NA	0.081	5.1e-06	NA	1.1e-03	NA	2.6e-04
11	GTEx	Skin Not Sun Exposed Suprapubic	0.2510	0.0740	2.2e-05	0.141	NA	0.100	NA	0.102	3.6e-08	NA	3.9e-06	NA	3.1e-06
12	GTEx	Skin Sun Exposed Lower leg	0.0490	0.0250	9.2e-03	0.040	NA	0.003	NA	0.016	2.7e-04	NA	1.7e-01	NA	1.5e-02
13	GTEx	Stomach	0.1500	0.0570	3.3e-04	0.101	NA	0.075	NA	0.096	1.6e-05	NA	1.9e-04	NA	2.5e-05
14	GTEx	Thyroid	0.0500	0.0250	8.6e-03	0.012	NA	0.000	NA	0.009	4.1e-02	NA	3.3e-01	NA	5.8e-02
15	METSIM	Adipose	0.0577	0.0217	2.6e-05	0.006	0.029	0.008	0.029	0.012	3.2e-02	2.8e-05	2.2e-02	3.0e-05	6.0e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Medication: Levothyroxine sodium	14.1	23.9	45.0	6.4	4.2	5.6	4.2	2.2	5.4	4.5	6.7	5.6	6.7	4.4	4.5	5.3	2.2	2.1
Hypothyroidism/myxoedema (self-reported)	12.8	24.9	48.2	6.7	4.2	5.7	4.1	2.6	5.4	4.5	6.9	5.8	6.9	4.4	4.5	5.3	1.1	2.5
Hypothyroidism (self reported)	11.0	25.4	49.7	6.8	4.3	5.8	4.0	1.6	5.3	4.6	7.0	6.1	7.0	4.3	4.6	5.3	0.9	3.3
Breastfed as a baby	9.8	12.1	17.5	-3.2	-3.7	-3.8	-3.6	-3.6	-4.2	-3.8	-3.3	-4.0	-3.4	-4.2	-3.8	-3.8	-1.3	-0.4
Medication: Co-codamol	9.4	10.9	15.0	3.9	3.2	3.6	3.5	3.1	3.3	3.4	3.6	3.9	3.7	3.4	3.4	3.4	-0.1	2.0
Depression (Nagel 2018)	7.4	11.1	14.8	3.5	3.6	3.8	3.7	2.8	3.6	3.6	3.7	3.4	3.8	3.4	3.6	3.6	0.7	0.6
Taking other prescription medications	7.1	11.0	17.6	3.8	3.4	3.8	3.5	0.3	3.5	3.4	4.2	3.9	4.1	3.1	3.4	3.6	0.8	2.0
Frequency of depressed mood in last 2 weeks	6.9	9.7	15.0	3.6	3.2	3.6	3.5	1.8	3.2	3.2	3.9	3.4	3.9	3.0	3.1	3.4	0.1	1.5
Heart disease (mother)	6.1	7.4	11.2	2.1	3.2	3.0	3.0	2.1	2.9	3.3	2.5	2.7	2.6	3.3	3.3	3.2	0.1	1.6
Blood White Count	5.8	43.2	67.6	6.9	6.1	7.0	7.4	8.2	7.2	6.7	6.8	7.2	6.8	6.8	6.7	7.1	3.1	1.2
Illnesses of father: Heart disease	5.8	8.1	13.9	3.7	2.5	3.3	2.6	1.9	2.9	2.8	3.7	3.4	3.7	2.6	2.8	3.1	0.1	1.2
Medication: Atorvastatin	5.3	6.5	10.0	3.2	2.4	2.8	2.4	1.9	2.7	2.6	3.0	3.0	2.9	2.6	2.6	2.6	-0.8	1.9
Number of self-reported non-cancer illnesses	5.2	8.9	15.7	4.0	2.8	3.3	3.1	0.9	2.8	2.9	3.6	3.5	3.7	2.5	2.9	3.1	-0.9	3.0
Medication: Gliclazide	5.1	5.7	8.0	2.5	2.8	2.6	2.3	2.5	2.5	2.5	2.6	2.8	2.5	2.4	2.5	2.4	0.9	1.4
Heart disease (siblings)	5.0	6.1	9.1	2.4	3.0	2.6	3.0	2.4	2.6	2.8	2.1	2.6	2.2	2.8	2.8	2.3	0.9	1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	4.6	6.1	8.7	2.8	2.8	2.8	3.0	1.8	2.6	2.6	2.7	2.7	2.8	2.4	2.6	2.5	1.1	0.3
Long-standing illness, disability or infirmity	4.4	6.7	11.6	3.4	2.5	2.9	2.8	0.7	2.4	2.6	3.2	3.1	3.3	2.3	2.6	2.8	-0.8	1.0
Coronary Artery Disease (CAD)	4.2	5.0	7.7	2.3	2.8	2.6	0.0	1.6	2.3	2.7	2.2	2.3	2.2	2.7	2.7	2.6	-0.2	1.8
Prostate Cancer	4.1	5.7	7.6	1.9	2.8	2.5	2.8	2.7	2.3	2.7	2.1	2.5	2.1	2.6	2.7	2.6	0.4	2.3
Alzheimer’s Disease (in mother)	3.7	4.3	6.2	2.5	2.0	2.2	2.3	1.9	1.8	2.1	2.1	2.1	2.2	2.1	2.1	1.9	-1.7	1.9
Migraine (self-reported)	3.6	4.4	6.9	1.6	2.3	2.3	2.6	-0.1	2.4	2.3	2.2	2.4	2.3	2.4	2.3	2.2	0.8	1.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.6	4.2	10.5	1.7	2.0	2.1	2.3	1.6	1.9	2.0	2.1	2.0	2.0	2.1	2.1	2.1	0.2	3.2
Pain all over the body in last month	3.4	3.6	4.9	1.8	1.9	2.1	2.1	1.4	2.0	2.2	1.9	2.2	1.9	2.1	2.1	2.2	-0.3	1.4
Asthma	3.4	6.6	9.9	2.4	2.5	3.0	2.5	0.1	2.9	2.8	3.0	2.8	3.0	2.8	2.8	3.1	0.4	2.1
Body Mass Index (BMI) (2010)	3.3	4.5	6.5	-1.4	-2.5	-2.2	-2.5	-1.2	-2.2	-2.4	-1.9	-2.2	-1.9	-2.5	-2.4	-2.3	0.8	-2.3
Ulcerative Colitis	3.2	4.7	7.1	-2.5	-2.7	-2.4	-2.3	-1.7	-2.0	-2.4	-2.0	-2.6	-2.1	-2.1	-2.4	-2.2	1.0	-1.5
Father’s age at death	3.2	4.3	7.5	-1.8	-2.5	-2.0	-2.7	-2.4	-1.9	-2.3	-1.6	-2.5	-1.7	-2.4	-2.3	-1.9	1.1	-0.9
Other serious medical condition/disability diagnosed by doctor	3.1	4.0	7.5	2.7	1.6	2.3	2.4	1.1	2.0	1.9	2.6	2.1	2.6	1.8	1.9	2.1	-0.6	0.8
Medication for pain relief, constipation, heartburn	3.1	5.3	7.7	-2.3	-2.8	-2.4	-2.5	-2.0	-2.4	-2.4	-2.4	-2.4	-2.4	-2.5	-2.3	-2.2	0.0	-2.0
Supplements: Vitamin C	3.1	3.7	6.2	1.5	2.0	2.2	2.3	1.0	2.2	2.3	1.6	2.2	1.8	2.5	2.3	2.2	0.4	0.9
Irritable Bowel Disease (IBD)	2.9	7.0	12.7	-2.1	-3.6	-3.0	-3.1	-2.2	-2.8	-3.4	-2.1	-2.7	-2.1	-2.8	-3.3	-2.6	-1.4	-1.1
Age at First Birth	2.9	4.2	10.2	-1.4	-2.4	-2.1	-2.7	-3.2	-1.8	-2.4	-1.3	-2.0	-1.4	-2.3	-2.4	-2.2	0.5	-1.0
Ever had hysterectomy (womb removed)	2.9	3.3	5.4	-1.3	-2.1	-2.0	-1.6	-1.3	-2.2	-2.0	-1.7	-1.9	-1.7	-1.8	-2.0	-2.0	-2.3	0.2
High blood pressure (mother)	2.9	4.1	6.6	-1.7	-2.6	-2.1	-2.4	-2.3	-2.0	-2.1	-1.7	-2.1	-1.7	-2.2	-2.2	-1.9	-0.5	-2.2
Asthma (self-reported)	2.9	5.8	8.6	2.2	2.4	2.8	2.4	-0.1	2.7	2.6	2.9	2.6	2.9	2.6	2.6	2.9	0.6	1.9
Tinnitus: Yes, now most or all of the time	2.9	3.4	5.2	-1.4	-2.1	-1.9	-1.9	-1.9	-2.2	-2.1	-1.5	-1.9	-1.5	-2.3	-2.1	-1.9	-0.6	-1.7
Diabetes (mother)	2.8	3.6	4.6	1.8	1.8	2.1	2.1	1.9	2.0	1.9	2.0	2.0	2.1	1.9	1.9	2.1	1.8	0.2
Heel bone mineral density (BMD) T-score, automated (right)	2.8	6.3	14.8	-0.7	-2.7	-2.4	-3.4	-1.7	-2.2	-3.1	-1.2	-2.1	-1.3	-3.3	-3.1	-2.9	1.3	-3.8
Eye problems/disorders: Cataract	2.7	3.1	5.8	2.3	1.2	1.7	1.3	0.1	1.5	1.5	1.9	1.8	2.0	1.8	1.5	1.7	-2.4	2.4
Lung FVC	2.6	13.5	23.6	-4.4	-3.5	-4.2	-3.0	-0.5	-3.5	-3.5	-4.9	-4.2	-4.7	-3.2	-3.5	-4.1	1.0	-3.9
Diabetes (father)	2.6	3.2	7.4	1.6	1.9	1.8	1.4	1.9	1.6	2.0	1.3	2.1	1.3	1.7	1.9	2.0	-0.8	2.7
Serious illness, injury or assault to yourself	2.6	3.1	5.2	1.9	2.1	2.0	2.3	1.4	1.9	2.0	1.9	1.7	1.9	1.7	1.9	1.8	0.6	0.1
Eye problems/disorders: None of the above	2.6	3.0	6.0	-2.1	-1.2	-1.8	-1.5	0.0	-1.5	-1.7	-1.9	-1.8	-1.9	-1.6	-1.7	-1.8	1.8	-2.5
Medication: Aspirin	2.6	3.4	8.7	3.0	1.8	2.0	1.3	1.3	1.5	1.5	2.6	1.9	2.5	1.4	1.4	1.7	-1.1	1.5
Ever taken oral contraceptive pill	2.6	2.9	5.2	-2.1	-1.4	-1.9	-1.6	-1.3	-1.7	-1.5	-2.3	-1.7	-2.3	-1.6	-1.6	-1.9	0.6	-1.6
Ulcerative Colitis (UC)	2.5	4.7	8.9	-1.8	-3.0	-2.4	-2.7	-1.2	-2.3	-2.7	-1.7	-2.5	-1.8	-2.3	-2.7	-2.3	-0.8	-1.0
Lupus	2.5	3.8	6.5	2.2	2.1	2.2	2.6	0.6	1.8	2.2	1.8	2.2	2.0	1.8	2.1	2.4	0.6	1.6
Rheumatoid Arthritis	2.5	3.4	5.2	2.1	2.0	2.1	0.0	1.0	2.0	1.9	2.3	1.9	2.2	2.1	1.9	1.9	-0.7	2.0
Respiratory disease	2.4	5.3	7.8	1.8	2.5	2.7	2.5	0.4	2.8	2.7	2.4	2.3	2.5	2.7	2.6	2.8	1.3	1.0
Wheeze or whistling in the chest in last year	2.4	4.2	5.9	2.3	2.0	2.2	2.2	1.1	1.9	2.0	2.3	2.3	2.4	2.1	2.0	2.3	-0.8	2.2
Neuroticism (2016)	2.3	3.3	7.2	2.7	1.4	1.9	2.2	1.6	1.5	1.7	2.0	1.9	2.0	1.6	1.9	1.9	-1.1	1.3
Age when periods started (menarche)	2.3	5.4	8.8	1.5	2.6	2.5	2.4	1.9	2.5	2.7	1.8	2.4	1.9	2.6	2.7	2.7	0.7	3.0
Type 2 Diabetes (T2D) (2018)	2.2	4.1	7.5	2.4	2.0	2.3	1.7	2.0	2.0	1.7	2.7	2.5	2.7	1.5	1.8	2.0	1.6	0.9
Stomach or abdominal pain in last month	2.2	2.8	5.5	1.3	1.8	1.8	2.3	0.8	1.7	2.0	1.4	1.4	1.3	1.9	2.0	2.1	-0.2	1.6
Leg fat percentage (right)	2.2	8.1	13.0	-2.6	-2.9	-3.2	-3.1	-0.6	-3.6	-2.8	-3.6	-2.7	-3.4	-3.0	-2.8	-3.0	-2.7	-0.5
Back pain experienced in last month	2.2	3.2	5.4	-1.3	-1.8	-2.0	-2.2	-0.9	-2.3	-2.0	-1.8	-2.1	-1.8	-2.3	-2.0	-1.9	-0.6	0.0
Allergy or Eczema	2.1	5.4	12.6	2.8	1.7	2.6	1.9	-0.7	2.2	1.9	3.5	2.4	3.5	1.8	1.9	2.5	0.1	2.8
Crohns Disease (2012)	2.0	3.2	5.3	-1.6	-2.3	-2.1	0.0	-2.3	-1.9	-2.2	-1.6	-1.7	-1.6	-1.9	-2.2	-1.9	-0.9	-0.9
Time employed in main current job	2.0	2.3	6.0	-2.4	-0.9	-1.6	-1.1	-0.1	-1.5	-1.2	-2.0	-1.7	-2.0	-1.2	-1.2	-1.6	0.8	-1.4
Forced expiratory volume in 1-second (FEV1), predicted	2.0	4.2	5.8	2.4	2.3	2.3	1.8	2.1	2.2	2.2	2.3	2.1	2.2	2.0	2.2	2.2	0.3	0.2
Osteoarthritis (self-reported)	2.0	2.6	4.1	1.4	1.7	1.8	1.5	0.2	2.0	1.8	1.6	1.8	1.6	1.8	1.9	1.9	1.7	-0.7
Medication: Aspirin	2.0	2.6	7.2	2.7	1.5	1.8	1.1	1.0	1.4	1.3	2.4	1.7	2.3	1.2	1.2	1.5	-0.8	0.9
Alzheimer’s Disease (in father)	1.9	2.1	4.0	-2.0	-1.2	-1.6	-1.4	1.1	-1.4	-1.3	-1.8	-1.8	-1.8	-0.9	-1.3	-1.2	-1.0	-1.4
Qualifications: CSEs or equivalent	1.9	2.5	3.9	1.8	1.9	1.7	1.8	1.7	1.4	1.9	1.3	2.0	1.3	1.5	1.9	1.7	0.0	0.5
Alcohol intake versus 10 years previously	1.9	2.8	4.9	-2.0	-1.6	-1.9	-1.5	-0.8	-1.8	-1.6	-2.2	-1.7	-2.2	-1.8	-1.6	-1.8	0.4	-1.0
Verbal and Numeric Reasoning (VNR)	1.8	4.4	6.7	-1.7	-2.5	-2.2	-2.1	-1.9	-2.3	-2.2	-2.0	-2.6	-2.1	-2.2	-2.3	-2.2	-0.9	-1.8
Serious illness, injury or assault of a close relative in last 2 years	1.8	2.1	3.9	1.8	1.3	1.7	1.3	0.8	1.5	1.4	1.9	1.3	2.0	1.4	1.5	1.7	-0.7	-0.2
Medication: Lansoprazole	1.8	2.1	4.4	-0.2	2.0	1.5	1.9	0.9	1.5	2.0	0.7	1.1	0.8	2.1	1.9	1.6	-0.3	1.1
Headache pain in last month	1.8	3.1	8.8	1.2	1.8	1.8	2.2	0.1	1.5	2.1	1.3	1.7	1.4	1.9	2.1	2.0	-0.8	3.0
Overall health rating	1.8	3.8	7.4	2.3	1.9	1.9	2.5	2.7	1.8	2.0	1.8	2.0	1.9	1.9	1.9	2.1	-0.5	1.3
Diabetes diagnosed by doctor	1.8	2.9	5.6	2.0	1.5	1.7	1.6	2.4	1.6	1.3	2.1	2.2	2.1	1.1	1.3	1.6	1.7	0.3
HDL Cholesterol	1.7	2.8	4.9	-2.2	-1.9	-1.7	-1.0	-1.7	-1.9	-1.3	-2.1	-1.9	-2.1	-1.4	-1.5	-1.6	-1.2	-0.1
Heel T-Score	1.7	13.6	35.3	-2.3	-3.9	-3.6	-4.4	-1.4	-3.0	-4.3	-2.4	-3.3	-2.6	-4.3	-4.3	-4.2	3.1	-5.9
Medication: Atenolol	1.7	2.1	3.2	1.1	1.8	1.5	1.6	1.8	1.5	1.6	1.2	1.7	1.3	1.7	1.6	1.5	0.1	0.7
Had major operations	1.7	2.0	3.0	1.4	1.5	1.6	1.3	0.5	1.4	1.5	1.6	1.6	1.7	1.4	1.5	1.7	0.2	1.3
Leg fat percentage (left)	1.7	6.3	11.5	-2.4	-2.4	-2.9	-2.6	-0.2	-3.3	-2.3	-3.4	-2.4	-3.2	-2.6	-2.3	-2.5	-2.6	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	1.6	3.7	11.7	-0.5	-1.8	-1.5	-2.6	-0.9	-1.2	-2.2	-0.6	-1.2	-0.7	-2.3	-2.2	-2.2	2.6	-3.4
Allergy	1.6	3.6	7.1	-2.1	-1.4	-2.1	-1.8	1.0	-1.9	-1.6	-2.7	-2.0	-2.7	-1.6	-1.7	-2.1	-0.2	-2.2
Shortness of breath walking on level ground	1.6	1.9	2.7	1.4	1.3	1.5	1.1	-0.3	1.4	1.4	1.5	1.6	1.5	1.6	1.4	1.5	-1.4	0.9
Suffer from ‘nerves’	1.6	2.5	4.3	2.1	1.7	1.7	1.6	1.4	1.8	1.5	1.8	1.9	1.8	1.6	1.5	1.6	0.9	-0.3
Leg pain on walking	1.6	2.0	3.7	1.2	1.9	1.5	1.5	0.6	1.5	1.5	1.4	1.8	1.5	1.6	1.5	1.5	1.0	0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.6	1.9	4.1	0.6	1.6	1.4	1.7	0.9	1.3	1.6	1.0	1.4	1.2	1.6	1.6	1.4	-0.6	2.0
Mouth/teeth dental problems: Mouth ulcers	1.6	2.6	8.5	-0.7	-1.9	-1.5	-1.9	-2.9	-1.7	-1.9	-0.6	-1.4	-0.7	-1.9	-1.9	-1.4	-1.2	0.4
Neuroticism (Nagel 2018)	1.5	3.5	5.3	1.5	2.0	2.0	2.3	1.8	2.0	2.0	2.0	2.1	2.0	1.9	2.0	2.1	1.0	0.8
Height	1.5	29.3	60.7	7.2	5.5	5.5	5.2	7.8	4.8	5.3	5.4	5.3	5.5	5.0	5.3	5.3	-1.5	4.2
Systolic blood pressure, automated reading	1.5	4.4	6.0	-1.3	-2.4	-2.4	-2.1	-0.7	-2.4	-2.4	-2.2	-2.1	-2.1	-2.1	-2.4	-2.4	-1.6	-2.1
Vitamin and mineral supplements	1.5	2.0	4.1	-0.9	-1.7	-1.5	-1.7	-0.5	-1.7	-1.7	-1.0	-1.6	-1.1	-2.0	-1.6	-1.5	0.5	-1.1
Hayfever, allergic rhinitis or eczema	1.5	3.2	7.2	2.0	1.4	2.0	1.7	-0.9	1.8	1.4	2.6	1.8	2.7	1.5	1.5	1.9	0.4	1.9
Heart attack	1.5	1.9	3.9	1.9	1.4	1.6	1.2	0.2	1.3	1.2	1.9	1.5	2.0	0.9	1.2	1.4	1.2	0.2
Mouth/teeth dental problems: Dentures	1.5	2.6	5.2	1.6	1.9	1.6	1.5	2.3	1.5	1.6	1.3	1.8	1.4	1.7	1.6	1.6	-0.3	1.4
Medication: Allopurinol	1.5	2.0	3.4	0.6	1.8	1.5	1.8	0.2	1.5	1.8	1.0	1.5	1.0	1.6	1.8	1.8	1.3	0.8
Miserableness	1.5	2.5	4.0	1.1	2.0	1.7	1.9	1.1	1.7	1.8	1.6	1.7	1.5	1.6	1.8	1.8	1.0	1.2
Medication: Blood pressure	1.5	2.9	5.6	-0.2	-2.4	-1.6	-2.0	-1.4	-1.9	-2.2	-0.6	-1.6	-0.6	-2.2	-2.3	-1.9	-1.2	-1.4
Intelligence (Savage-Jansen 2018)	1.4	4.4	7.2	-1.9	-2.4	-2.2	-2.3	-2.7	-2.2	-2.3	-1.9	-2.5	-2.0	-2.2	-2.3	-2.2	-1.1	-0.6
Worry (Nagel 2018)	1.4	3.0	4.9	2.0	1.5	1.8	1.7	2.2	1.9	1.5	2.2	2.1	2.1	1.6	1.5	1.8	0.9	0.4
Falls in the last year	1.4	1.9	3.8	2.0	1.6	1.5	1.0	0.9	1.7	1.5	1.5	1.3	1.6	1.4	1.5	1.3	0.6	-0.9
Standing height	1.4	13.5	27.4	5.2	3.6	3.9	3.2	4.5	3.3	3.4	4.3	3.8	4.2	3.2	3.4	3.5	-0.9	3.1
Health satisfaction	1.4	1.8	2.5	1.2	1.5	1.6	1.5	0.8	1.5	1.6	1.3	1.6	1.4	1.4	1.5	1.6	0.4	-0.0
Chest pain or discomfort	1.4	2.0	6.9	2.6	1.0	1.4	1.1	0.8	1.0	0.9	2.1	1.8	2.0	0.7	0.9	1.3	-0.6	1.1
Illnesses of father: None of the above (group 1)	1.4	1.7	4.9	-2.2	-0.8	-1.4	-1.2	-0.5	-1.1	-1.1	-1.7	-1.7	-1.7	-1.0	-1.1	-1.4	0.9	-0.5
Risk taking	1.4	2.1	5.6	-2.4	-1.2	-1.6	-1.4	-0.7	-1.4	-1.3	-1.9	-1.7	-1.9	-1.1	-1.3	-1.4	-0.8	-0.5
Heart attack/myocardial infarction (self-reported)	1.4	1.8	3.8	1.9	1.4	1.5	1.1	-0.1	1.2	1.2	1.8	1.5	1.9	0.9	1.2	1.5	0.7	0.4
Crohns Disease (2017)	1.3	2.8	5.3	-1.1	-2.3	-1.8	-2.0	-1.8	-1.8	-2.2	-1.2	-1.5	-1.1	-1.7	-2.1	-1.6	-1.6	-0.5
Hearing difficulty/problems: Yes	1.3	2.0	10.7	-0.4	-1.5	-1.0	-1.7	-3.3	-1.1	-1.5	-0.3	-0.9	-0.3	-1.7	-1.5	-1.0	-0.3	-1.2
Ever used hormone-replacement therapy (HRT)	1.3	1.7	4.0	-2.0	-1.0	-1.4	-0.8	0.6	-1.4	-0.9	-1.9	-1.4	-1.9	-0.8	-0.9	-1.1	-1.3	-0.6
Eye problems/disorders: Diabetes related eye disease	1.3	1.4	2.3	1.3	0.8	1.1	1.3	1.4	1.3	0.8	1.5	1.4	1.5	0.9	0.8	1.0	1.5	-0.9
Impedance of arm (right)	1.3	5.9	12.4	1.6	2.5	2.3	2.4	2.0	1.9	2.5	2.1	2.6	2.1	2.8	2.5	2.3	-3.5	2.7
Depression (self-reported)	1.3	1.5	2.9	0.5	1.6	1.2	1.6	1.5	1.2	1.6	0.4	1.2	0.6	1.7	1.6	1.3	-0.4	0.9
Hair/balding pattern: Pattern 4	1.3	3.2	5.5	-0.6	-1.9	-1.8	-2.4	-1.6	-1.8	-1.9	-1.4	-1.9	-1.4	-2.3	-1.9	-1.9	-0.6	-2.1
Average weekly beer plus cider intake	1.3	1.9	8.5	-0.7	-1.2	-1.1	-1.3	-1.1	-0.9	-1.2	-0.8	-0.9	-0.8	-1.6	-1.3	-1.3	1.9	-2.9
Age started oral contraceptive pill	1.3	1.6	2.8	-0.9	-1.4	-1.2	-1.7	-1.7	-1.3	-1.5	-0.8	-1.3	-0.8	-1.3	-1.5	-1.3	-0.4	-0.9
Blood Eosinophil Count	1.2	9.1	13.8	3.7	2.9	3.5	3.3	2.6	3.3	3.2	3.4	3.3	3.4	3.1	3.2	3.2	1.0	-0.4
Sensitivity / hurt feelings	1.2	2.0	4.3	0.7	2.0	1.4	2.1	1.0	1.4	1.9	0.8	1.4	0.9	1.6	1.8	1.8	0.2	0.8
Medication: Cholesterol lowering	1.2	1.9	5.6	1.3	1.5	1.4	1.6	2.4	1.3	1.4	1.2	1.5	1.2	1.2	1.3	1.2	0.6	-0.6
Gout (self-reported)	1.2	1.7	4.8	0.7	1.4	1.3	1.6	0.1	1.3	1.4	1.1	1.4	1.1	1.1	1.4	1.4	2.2	0.5
Medication: Ventolin 100micrograms inhaler	1.2	1.6	3.3	1.5	1.0	1.4	1.1	-0.3	1.3	1.1	1.8	1.5	1.7	1.2	1.1	1.3	0.2	0.7
Wears glasses or contact lenses	1.2	1.3	2.4	-0.9	-1.5	-1.1	-1.2	-1.5	-1.3	-1.3	-0.8	-1.1	-0.8	-1.2	-1.3	-1.2	-1.1	0.6
High cholesterol (Self-reported)	1.2	2.1	7.3	0.9	1.6	1.5	1.0	2.7	1.5	1.5	1.2	1.6	1.2	1.5	1.4	1.3	1.0	0.8
Type 2 Diabetes (T2D) (2012)	1.1	1.2	3.9	1.7	0.8	1.1	0.0	0.4	0.8	0.4	2.0	1.8	1.9	0.6	0.6	0.9	0.2	0.6
Bilateral oophorectomy (both ovaries removed)	1.1	1.2	2.2	-1.3	-1.1	-1.3	-0.6	-0.6	-1.4	-1.1	-1.3	-0.9	-1.3	-1.0	-1.1	-1.3	-1.5	0.3
Hearing difficulty/problems with background noise	1.1	1.8	9.0	-0.5	-1.5	-1.0	-1.5	-3.0	-1.1	-1.3	-0.6	-0.8	-0.4	-1.3	-1.3	-1.0	-0.9	-1.8
Diabetes (self-reported)	1.1	1.7	3.3	1.4	1.2	1.3	1.1	1.8	1.2	1.0	1.5	1.7	1.4	0.7	1.0	1.2	1.8	0.1
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.8	3.2	1.7	1.5	1.5	1.6	-0.7	1.2	1.2	1.8	1.5	1.8	1.0	1.2	1.2	0.4	0.7
Impedance of arm (left)	1.1	5.1	16.1	1.3	2.2	1.9	2.1	2.1	1.5	2.2	1.6	2.2	1.6	2.5	2.2	2.0	-4.0	3.0
Peak expiratory flow (PEF)	1.1	2.6	4.0	1.4	1.7	1.6	1.7	1.8	1.9	1.7	1.2	1.6	1.4	1.8	1.7	1.5	2.0	0.2
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	2.3	1.4	1.3	1.3	0.8	-0.3	1.0	1.4	1.0	1.5	1.1	1.2	1.4	1.3	-1.1	1.0
Medication for cholesterol, blood pressure or diabetes	1.1	1.8	3.7	-1.8	-1.2	-1.4	-1.4	-1.9	-1.1	-1.2	-1.5	-1.5	-1.5	-1.1	-1.2	-1.2	1.0	-0.2
Birth weight	1.1	2.4	9.1	-1.2	-1.5	-1.5	-1.7	-3.0	-1.7	-1.3	-1.4	-1.6	-1.4	-1.6	-1.4	-1.2	-0.9	0.1
Sitting height	1.0	7.3	14.6	3.8	2.6	3.0	2.4	2.6	2.6	2.6	3.2	2.8	3.2	2.4	2.6	2.9	-0.2	2.2
Worrier / anxious feelings	1.0	1.9	3.9	1.5	1.3	1.5	1.2	0.1	1.6	1.0	2.0	1.8	2.0	1.0	1.0	1.2	1.6	0.7
Length of working week for main job	1.0	1.1	3.0	-1.3	-0.3	-1.1	-0.3	0.6	-1.0	-0.6	-1.7	-1.2	-1.7	-0.5	-0.6	-1.2	-1.3	0.0
Medication: Amlodipine	1.0	1.4	2.9	-1.7	-1.3	-1.3	-0.8	0.2	-1.2	-1.0	-1.7	-1.4	-1.7	-0.9	-1.0	-1.1	-0.4	-1.2
Commuting to job workplace: Car/motor vehicle	1.0	1.1	4.2	-1.1	-1.1	-1.0	-1.0	-0.3	-0.8	-0.9	-1.1	-1.1	-1.1	-0.9	-1.0	-0.9	0.0	-2.0
Commuting to job workplace: Public transport	1.0	1.2	3.9	-0.4	-1.3	-0.8	-1.1	-2.0	-1.1	-1.3	0.2	-0.7	0.0	-1.5	-1.3	-1.1	-0.1	1.0
Eye problems/disorders: Glaucoma	1.0	1.2	4.3	-0.7	-1.3	-1.0	-1.1	-2.1	-1.3	-1.1	-0.8	-1.1	-0.9	-1.3	-1.1	-0.8	-0.8	-0.3
Pain type(s) experienced in last month: Hip pain	1.0	1.3	1.9	0.6	1.3	1.2	1.3	1.4	1.3	1.2	0.9	0.8	1.0	1.3	1.2	1.1	1.4	-0.6
Fractured/broken bones in last 5 years	1.0	1.3	3.0	0.3	1.1	1.1	1.7	0.8	1.1	1.3	0.8	1.2	0.9	1.6	1.4	1.0	-0.7	1.0
Number of treatments/medications taken	0.9	1.7	2.9	1.2	1.3	1.5	1.3	-0.6	1.3	1.3	1.7	1.4	1.7	1.1	1.3	1.4	-0.0	1.1
Had other major operations	0.9	1.1	2.0	-0.9	-0.9	-1.1	-0.7	-1.3	-1.2	-0.8	-1.4	-1.4	-1.3	-0.8	-0.8	-0.9	-1.0	-1.0
Neuroticism score	0.9	1.9	2.9	0.9	1.6	1.5	1.7	0.7	1.5	1.6	1.3	1.5	1.3	1.5	1.5	1.5	1.1	1.1
Hair/balding pattern: Pattern 3	0.9	1.3	6.4	-0.6	-1.1	-0.9	-1.2	-1.3	-0.9	-1.1	-0.8	-0.9	-0.7	-1.3	-1.1	-0.9	0.6	-2.5
Pulse wave reflection index	0.9	1.1	7.4	0.2	-0.9	-0.3	-1.4	-2.7	-0.4	-0.9	0.6	-0.3	0.5	-1.2	-1.0	-0.7	0.5	-1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.1	2.7	0.6	1.1	1.1	1.6	0.8	1.2	1.4	0.6	1.1	0.7	1.2	1.3	1.4	0.6	0.2
Average weekly champagne plus white wine intake	0.9	1.3	2.3	-1.2	-1.0	-1.2	-0.8	-1.4	-1.3	-1.1	-1.1	-1.2	-1.2	-0.9	-1.1	-1.2	-1.5	0.5
Medication: Bendroflumethiazide	0.9	1.4	2.4	-1.0	-1.2	-1.3	-1.5	-0.9	-1.5	-1.2	-1.1	-1.2	-1.1	-1.2	-1.2	-1.2	-1.5	0.3
Alcohol drinker status: Never	0.9	1.0	2.3	-0.5	-1.3	-1.0	-1.2	-1.0	-1.2	-1.2	-0.6	-0.9	-0.5	-1.1	-1.2	-1.0	-1.5	-0.2
Relative age of first facial hair	0.8	1.7	2.6	1.2	1.2	1.3	1.3	1.5	1.4	1.1	1.5	1.4	1.5	1.4	1.1	1.4	-0.2	1.6
Impedance of leg (right)	0.8	3.9	33.7	-1.4	-0.6	-1.2	-0.6	-1.1	-1.6	-0.8	-1.1	-0.8	-1.1	-0.3	-0.9	-1.2	-5.8	3.2
Had menopause	0.8	1.0	2.5	-0.4	-1.5	-0.9	-1.2	-0.3	-1.2	-1.0	-0.7	-0.9	-0.7	-1.1	-1.0	-0.9	-1.6	-0.2
Medication: Ramipril	0.8	1.0	1.9	1.4	0.7	1.1	0.7	1.2	1.1	0.8	1.3	1.1	1.3	0.7	0.8	1.0	1.1	-0.1
Number of children fathered	0.8	0.9	1.5	1.2	0.8	1.2	0.6	1.1	1.0	1.0	1.2	1.1	1.2	0.8	1.1	1.1	0.5	-0.1
Age at first live birth	0.8	1.5	4.3	1.2	0.7	1.2	0.7	-1.1	1.5	0.6	1.7	0.9	1.7	0.8	0.7	0.8	2.1	-1.3
Medication: Ibuprofen	0.8	1.0	3.3	0.3	1.3	0.9	1.2	0.7	1.2	1.1	0.3	0.4	0.5	1.2	1.1	0.9	1.8	-0.8
Mood swings	0.8	1.4	7.1	-0.1	1.5	1.0	1.5	1.0	1.2	1.1	0.6	1.3	0.6	1.0	1.1	0.8	2.7	0.8
Leg predicted mass (right)	0.8	4.0	9.1	2.8	1.8	2.0	1.4	3.0	1.9	1.9	1.8	1.9	1.8	1.4	1.9	1.9	2.8	-0.7
Medication: Lisinopril	0.8	1.0	4.5	0.2	-1.0	-0.9	-0.5	0.5	-1.3	-1.1	-0.5	-0.9	-0.6	-1.1	-1.2	-1.1	-2.1	0.4
Cholesterol lowering medication	0.8	1.1	4.2	1.2	0.7	1.1	0.7	2.1	1.0	0.8	1.4	1.3	1.4	0.8	0.7	0.7	0.5	0.4
Impedance of whole body	0.8	4.0	27.6	0.3	1.6	1.0	1.6	1.2	0.6	1.5	0.7	1.4	0.7	1.8	1.5	1.1	-5.2	3.6
Depressed Affect (Nagel 2018)	0.7	1.5	2.7	0.7	1.5	1.3	1.6	1.1	1.3	1.4	1.1	1.2	1.0	1.2	1.4	1.3	1.0	0.7
Alzheimer’s Disease (including proxy)	0.7	1.0	4.7	0.7	0.8	0.6	0.9	2.1	0.5	0.8	0.4	0.4	0.5	1.0	0.8	0.6	-2.2	0.7
Systolic Blood Pressure	0.7	3.5	9.9	-0.2	-2.4	-2.0	-1.8	-0.6	-2.3	-2.2	-1.2	-1.5	-1.2	-1.8	-2.3	-1.9	-3.1	-1.2
Cardiovascular Disease	0.7	2.4	8.4	2.0	1.6	1.6	1.2	2.9	1.3	1.5	1.5	1.7	1.5	1.3	1.5	1.4	-0.1	0.5
Chronic bronchitis/emphysema (father)	0.7	0.8	1.3	0.8	0.9	0.8	0.9	-0.3	0.9	1.0	0.6	0.9	0.7	1.1	1.0	1.1	-1.1	1.0
Impedance of leg (left)	0.7	3.5	32.7	-1.2	0.2	-0.6	0.2	-0.6	-1.1	-0.1	-0.8	-0.3	-0.8	0.3	-0.1	-0.6	-5.7	3.7
Ever highly irritable/argumentative for 2 days	0.7	0.9	1.4	0.8	1.1	0.9	1.0	0.2	0.8	1.1	0.6	1.1	0.6	1.0	1.1	1.0	-0.9	1.2
Medication: Paracetamol	0.7	1.1	2.6	-0.3	1.6	1.0	1.3	1.3	1.1	1.4	0.1	0.8	0.1	1.5	1.4	1.1	0.4	0.4
High blood pressure (siblings)	0.7	1.1	3.2	-1.1	-1.1	-1.1	-1.1	-0.4	-1.2	-1.0	-1.0	-0.8	-1.1	-0.8	-1.0	-1.0	-1.8	0.2
Pulse wave peak to peak time	0.7	0.9	5.3	0.2	0.9	0.6	1.3	2.3	0.6	1.0	-0.1	0.6	-0.1	1.1	1.1	0.8	0.5	0.2
Number of full sisters	0.7	0.9	2.0	-0.6	-1.0	-1.0	-0.7	-0.4	-1.1	-0.9	-1.1	-1.1	-1.1	-0.9	-1.0	-0.8	-1.4	-0.7
Leg fat-free mass (right)	0.7	3.8	8.7	2.8	1.7	1.9	1.3	3.0	1.8	1.8	1.7	1.9	1.7	1.2	1.8	1.8	2.7	-0.7
Number of operations (self-reported)	0.7	1.1	4.2	0.3	1.2	0.6	1.6	-0.2	0.3	1.0	0.3	0.5	0.3	1.1	1.0	1.1	-2.0	1.5
Diastolic blood pressure, automated reading	0.7	2.3	6.5	-2.1	-1.0	-1.6	-1.1	0.8	-1.5	-1.0	-2.6	-1.7	-2.4	-1.0	-1.0	-1.6	0.1	-1.4
Fasting Glucose	0.6	0.7	4.9	0.5	-0.4	-0.3	-1.3	-1.3	-0.7	-0.3	0.2	0.1	0.2	-0.8	-0.7	-0.2	-2.2	-0.4
Triglycerides	0.6	1.0	2.3	-0.8	-1.1	-1.0	-1.5	-0.0	-0.8	-1.2	-0.8	-1.0	-0.9	-1.1	-1.1	-1.1	0.9	-0.7
Medication: Metformin	0.6	0.8	3.8	1.4	0.4	0.8	0.5	1.9	0.5	0.4	1.2	1.2	1.1	0.1	0.5	0.7	0.6	0.3
Townsend deprivation index at recruitment	0.6	0.9	1.5	-1.0	-0.6	-1.1	-0.8	-1.2	-1.0	-1.0	-1.1	-0.7	-1.0	-0.9	-1.0	-1.1	-0.6	0.3
Average weekly fortified wine intake	0.6	0.7	1.4	-1.2	-0.9	-0.9	-0.7	0.3	-0.9	-0.7	-1.1	-0.9	-1.1	-0.5	-0.6	-0.6	-1.0	0.5
Relative age voice broke	0.6	0.9	1.7	0.6	0.8	0.8	1.1	1.3	0.9	0.8	0.8	1.1	0.9	1.2	0.8	0.9	-0.3	1.2
Tinnitus: Yes, but not now, but have in the past	0.6	0.7	1.9	-1.1	-0.5	-0.8	-0.2	0.7	-0.9	-0.5	-1.1	-0.7	-1.1	-0.3	-0.5	-0.6	-1.4	0.8
Alcohol usually taken with meals	0.6	0.9	2.2	1.5	0.4	1.0	0.4	-0.1	0.8	0.7	1.4	0.9	1.4	0.7	0.7	1.1	-1.1	0.7
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	2.0	1.3	0.8	0.9	1.2	0.6	0.9	0.6	1.4	1.1	1.4	0.7	0.6	0.7	0.6	-0.1
Medication: Simvastatin	0.6	0.9	3.6	0.7	0.8	0.9	0.8	1.9	0.9	0.7	1.0	1.1	1.0	0.6	0.7	0.7	1.1	-0.6
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	2.4	-0.9	-1.1	-0.9	-0.9	-1.5	-0.8	-0.9	-0.7	-1.3	-0.8	-0.9	-0.9	-0.9	0.5	-1.0
Comparative height size at age 10	0.6	3.1	9.9	2.5	1.4	1.6	1.6	3.1	1.3	1.6	1.8	1.6	1.7	1.5	1.5	1.4	-1.0	1.8
Loneliness, isolation	0.6	0.8	5.6	-0.4	0.7	0.3	1.1	0.2	-0.1	0.8	-0.4	0.2	-0.5	0.8	0.8	0.4	-1.6	2.4
Unable to work because of sickness or disability	0.6	0.8	5.2	0.2	0.4	0.3	1.1	0.8	0.6	0.4	-0.0	0.3	0.2	0.4	0.3	0.1	1.9	-2.3
Pain experienced in last month	0.6	1.0	3.5	-0.9	-1.2	-0.9	-1.1	-0.6	-0.5	-1.1	-0.6	-0.9	-0.7	-0.9	-1.1	-1.0	1.1	-1.9
Supplements: Calcium	0.6	0.6	1.2	0.9	0.5	0.8	0.9	-0.9	0.8	0.5	1.0	0.7	1.1	0.6	0.5	0.8	1.1	-0.5
Schizophrenia vs Biploar Disorder	0.5	0.6	2.1	1.4	0.3	0.6	0.0	1.0	0.8	0.2	1.1	0.4	1.1	0.2	0.4	0.6	1.1	-0.5
Mean Putamen Volume	0.5	0.5	3.6	-0.1	-0.4	-0.5	-0.1	0.9	-0.7	-0.2	-1.0	-0.2	-1.0	-0.1	-0.2	-0.4	-1.9	0.8
HbA1C	0.5	0.5	2.1	0.2	-0.6	-0.4	-1.5	-1.2	-0.6	-0.6	0.2	-0.1	0.1	-0.9	-0.9	-0.4	-0.9	0.1
Schizophrenia (2014)	0.5	1.2	2.3	-0.5	-1.5	-1.1	-1.3	-0.6	-1.3	-1.4	-0.7	-1.4	-0.7	-1.4	-1.3	-1.2	0.1	-0.6
Neuroticism	0.5	1.1	1.6	0.9	1.3	1.1	1.2	0.4	1.1	1.1	1.2	1.2	1.1	0.9	1.1	1.1	0.7	0.6
Angina	0.5	0.7	1.7	0.9	1.0	0.8	0.5	1.3	0.9	0.9	0.8	0.9	0.7	0.9	0.9	0.8	-0.6	0.3
Medication for hormone replacement therapy	0.5	0.5	3.8	-0.9	-0.0	-0.5	-0.1	2.0	-0.3	-0.1	-1.1	-0.6	-1.0	0.0	-0.1	-0.4	-0.1	-0.2
Leg fat-free mass (left)	0.5	2.7	7.2	2.6	1.3	1.6	0.8	2.7	1.5	1.3	1.5	1.6	1.5	0.9	1.4	1.4	2.4	-0.7
Supplements: Glucosamine	0.5	0.7	5.2	-1.1	-0.3	-0.6	-0.6	0.2	-0.1	-0.3	-1.0	-0.8	-0.9	-0.1	-0.3	-0.4	0.1	-2.3
Body mass index (BMI)	0.5	2.3	4.2	-1.0	-1.5	-1.6	-1.8	0.6	-1.7	-1.3	-2.0	-1.3	-1.9	-1.7	-1.3	-1.4	0.9	-2.1
Leg predicted mass (left)	0.5	2.7	7.6	2.6	1.3	1.6	0.8	2.8	1.5	1.3	1.5	1.6	1.5	0.9	1.3	1.4	2.3	-0.7
Mouth/teeth dental problems	0.5	0.7	2.4	-1.2	-0.7	-0.6	-0.3	0.1	-0.4	-0.6	-0.8	-1.0	-0.8	-0.6	-0.6	-0.8	1.6	-1.2
Noisy workplace	0.5	0.6	4.2	0.7	-0.6	-0.1	-1.0	-2.1	-0.3	-0.5	0.6	0.5	0.6	-0.7	-0.5	-0.4	-0.4	-0.6
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	1.4	-0.0	1.1	0.6	0.9	0.9	0.9	1.0	-0.1	0.3	0.0	1.2	1.0	0.8	1.0	-0.2
Illnesses of mother	0.5	0.7	2.7	-1.3	-0.5	-0.7	-0.3	-0.1	-0.5	-0.6	-1.0	-0.6	-1.1	-0.6	-0.5	-0.7	1.6	0.7
Chronic bronchitis/emphysema (mother)	0.5	0.5	5.3	0.6	-0.3	-0.4	-0.3	0.1	-0.8	-0.4	-0.3	-0.3	-0.3	-0.6	-0.4	-0.4	-2.3	0.6
Comparative body size at age 10	0.5	1.5	3.0	-1.7	-1.1	-1.3	-1.0	-0.1	-1.2	-1.1	-1.6	-1.7	-1.6	-1.0	-1.0	-1.0	0.4	-1.1
Number of full brothers	0.5	0.6	3.9	-0.4	0.6	0.2	0.9	2.0	0.1	0.7	-0.6	0.3	-0.5	0.7	0.7	0.3	-0.6	1.2
Mean time to correctly identify matches	0.5	1.0	2.7	0.8	1.3	0.9	0.8	1.4	1.0	0.9	0.8	1.1	0.7	0.7	0.9	0.8	1.6	0.6
Leg fat mass (right)	0.5	2.0	3.7	-0.7	-1.4	-1.6	-1.8	0.9	-1.9	-1.3	-1.9	-1.2	-1.8	-1.6	-1.3	-1.4	-1.2	-0.4
Age at last live birth	0.5	0.8	5.1	0.6	0.2	0.8	-0.1	-1.0	1.1	0.3	1.1	0.3	1.1	0.3	0.3	0.5	2.2	-1.0
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	4.9	-0.4	-0.5	-0.4	-0.9	-1.1	-0.4	-0.2	-0.5	-0.5	-0.3	-0.5	-0.3	-0.1	-0.5	-2.2
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	1.1	0.9	0.9	0.8	0.6	-0.2	0.7	0.7	0.7	0.5	0.7	0.5	0.7	0.8	1.1	0.6
Breast cancer (self-reported)	0.5	0.6	1.3	-1.1	-0.3	-0.9	-0.3	-0.2	-0.8	-0.7	-1.1	-0.9	-1.2	-0.6	-0.7	-0.9	0.0	-0.5
Medication: Paracetamol	0.5	0.8	1.6	-0.7	1.2	0.7	1.2	1.2	0.9	1.2	-0.1	0.4	-0.1	1.3	1.2	0.7	0.9	0.2
Bipolar Disorder (2018)	0.4	0.7	2.3	-1.5	-0.7	-0.9	0.0	-0.7	-1.0	-0.6	-1.1	-1.0	-1.1	-0.8	-0.7	-0.6	-0.5	-0.1
Bipolar Disorder or Schizophrenia	0.4	0.9	1.5	-0.8	-1.1	-1.0	-0.9	-0.6	-1.1	-0.8	-0.9	-1.2	-0.9	-1.2	-1.0	-0.9	-1.0	-0.0
Major Depression (MDD)	0.4	0.5	4.7	1.1	-0.1	0.4	0.0	-0.4	-0.1	0.2	0.0	0.3	0.5	0.2	0.2	0.8	-2.2	0.7
Primary Biliary Cirrhosis	0.4	0.5	1.3	1.1	0.9	0.8	0.5	0.1	0.5	0.6	1.0	1.1	1.0	0.2	0.6	0.4	-0.2	1.0
Blood Red Count	0.4	3.8	13.7	-2.2	-1.8	-2.0	-1.5	0.1	-2.4	-1.4	-2.3	-2.0	-2.3	-1.3	-1.4	-1.7	-3.7	1.0
Waist Hip Ratio (WHR)	0.4	1.7	4.2	1.8	1.2	1.5	0.9	-1.0	1.2	0.9	2.0	2.0	2.0	0.5	0.9	1.0	0.9	-0.2
Tanning	0.4	4.9	11.1	-2.2	-2.5	-2.4	-2.2	-3.3	-2.4	-2.4	-2.0	-2.3	-2.0	-2.3	-2.4	-2.0	-1.0	-1.0
Hand grip strength (left)	0.4	1.2	2.5	-0.4	-1.4	-1.0	-1.4	-0.2	-0.8	-1.3	-0.5	-0.9	-0.5	-1.2	-1.3	-1.1	1.6	-1.5
Fed-up feelings	0.4	0.8	6.0	0.0	0.6	0.5	1.1	0.7	0.7	0.7	0.2	0.8	0.2	0.5	0.6	0.5	2.4	-0.7
Fluid intelligence score	0.4	0.8	1.9	-0.8	-1.1	-0.9	-0.7	-0.6	-0.8	-0.8	-1.0	-1.4	-1.0	-1.0	-0.9	-0.9	0.5	-1.0
Number of live births	0.4	0.5	1.8	-0.6	-0.5	-0.6	-1.2	-0.7	-0.8	-0.6	-0.6	-0.8	-0.6	-0.5	-0.6	-0.5	-1.4	0.1
Lung cancer (father)	0.4	0.5	0.8	-0.5	-0.8	-0.8	-0.5	0.0	-0.8	-0.8	-0.8	-0.6	-0.7	-0.8	-0.8	-0.9	0.5	-0.8
Pulse wave Arterial Stiffness index	0.4	0.5	3.6	0.2	-0.5	-0.3	-1.0	-1.9	-0.3	-0.7	0.4	-0.3	0.4	-0.8	-0.7	-0.5	-0.5	0.2
Tense / ‘highly strung’	0.4	0.6	2.0	1.4	0.6	0.7	0.6	1.0	0.5	0.3	1.3	0.9	1.1	0.2	0.3	0.4	0.3	0.7
Body fat percentage	0.4	1.7	6.0	-0.8	-0.8	-1.2	-1.3	1.4	-1.6	-0.7	-1.9	-0.6	-1.7	-1.0	-0.7	-1.0	-2.5	-0.1
Exposure to tobacco smoke outside home	0.4	0.5	2.4	0.8	1.2	0.6	0.6	1.5	0.5	0.7	0.3	0.6	0.3	0.6	0.7	0.5	-0.0	0.3
Mouth/teeth dental problems: Loose teeth	0.4	0.5	2.2	-0.3	-0.3	-0.6	-0.4	0.3	-0.3	-0.6	-0.4	-0.5	-0.4	-0.6	-0.6	-0.8	1.3	-1.5
Medication: Omeprazole	0.4	0.4	0.8	-0.9	-0.4	-0.8	-0.4	0.5	-0.7	-0.6	-0.8	-0.6	-0.9	-0.6	-0.6	-0.7	-0.6	0.5
Family relationship satisfaction	0.4	0.5	1.1	-0.3	0.9	0.6	0.9	1.0	0.5	1.0	-0.3	0.3	-0.2	0.8	1.0	0.5	0.6	-0.7
Knee pain experienced in last month	0.4	0.7	2.9	0.4	1.2	0.7	0.7	1.7	0.7	0.9	0.1	0.7	0.3	0.8	0.9	0.6	1.1	-0.3
Illnesses of siblings: Diabetes	0.4	0.5	2.4	-0.2	1.1	0.4	0.7	1.5	0.4	0.8	-0.3	0.7	-0.2	0.9	0.8	0.4	-0.4	0.8
Osteoporosis (self-reported)	0.4	0.4	3.2	-0.3	0.5	0.2	0.7	-0.7	-0.0	0.5	-0.1	0.2	-0.2	0.5	0.5	0.3	-1.1	1.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	6.7	-1.1	-0.3	-0.6	-0.0	0.8	-0.1	-0.4	-0.9	-0.5	-0.8	-0.4	-0.4	-0.6	2.6	-1.4
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.0	0.4	0.8	0.8	0.7	-0.3	1.0	0.8	0.8	0.6	0.8	0.9	0.8	0.8	0.0	-0.3
Alcohol drinker status: Previous	0.4	0.4	1.1	-0.3	-0.2	-0.6	-0.7	0.4	-0.9	-0.7	-0.7	-0.3	-0.7	-1.0	-0.7	-1.0	0.2	-0.3
Leg fat mass (left)	0.4	1.6	3.2	-0.6	-1.1	-1.4	-1.5	1.0	-1.7	-1.0	-1.8	-1.0	-1.7	-1.4	-1.0	-1.2	-1.2	-0.3
Reaction Time	0.3	0.7	3.1	0.1	1.0	0.4	0.7	1.5	0.6	0.5	0.2	0.9	0.1	0.4	0.5	0.3	1.8	0.8
Breast Cancer	0.3	0.8	6.4	-0.1	0.4	0.2	0.3	1.9	0.2	0.5	-0.0	-0.1	-0.2	0.9	0.4	0.6	-0.8	2.5
Blood Platelet Count	0.3	3.8	8.4	-0.9	-2.6	-2.0	-1.9	-1.8	-2.2	-2.2	-1.6	-1.7	-1.5	-2.0	-2.3	-1.8	-2.9	-0.8
Chronotype (morning person)	0.3	0.6	2.2	-0.4	0.7	0.5	0.8	1.3	0.6	0.8	0.0	0.5	0.1	1.0	0.8	0.6	-0.2	1.5
Pack years adult smoking proportion	0.3	0.4	1.4	-0.2	-0.6	-0.6	-0.8	-0.4	-0.6	-0.8	-0.3	-0.1	-0.2	-0.8	-0.8	-0.8	1.2	-0.9
Trunk fat percentage	0.3	1.0	6.7	0.1	0.1	-0.3	-0.5	2.3	-0.8	0.2	-1.0	0.2	-0.8	-0.2	0.1	-0.2	-2.6	0.3
Hand grip strength (right)	0.3	0.7	1.5	-0.4	-1.2	-1.0	-1.2	-0.2	-1.0	-1.1	-0.7	-0.7	-0.7	-1.0	-1.1	-0.9	0.4	-0.3
Hair/balding pattern: Pattern 2	0.3	0.4	2.6	-0.7	0.6	0.3	0.7	0.4	0.3	0.6	-0.1	0.3	-0.1	0.9	0.5	0.2	-1.0	1.6
Qualifications: None of the above	0.3	0.6	3.2	-0.3	0.2	-0.4	0.3	1.8	-0.5	0.0	-1.0	0.1	-0.9	0.1	0.1	-0.3	-1.2	1.3
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	0.9	0.5	0.3	0.5	0.7	-0.9	0.4	0.6	0.5	0.4	0.5	0.6	0.6	0.7	-1.0	0.6
Pulse rate	0.3	0.5	2.2	-0.7	0.7	0.4	0.7	1.5	0.6	0.8	-0.6	-0.1	-0.4	1.0	0.8	0.7	0.3	0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.9	5.9	-0.0	0.4	0.1	0.5	2.3	0.6	0.2	-0.4	0.2	-0.3	0.4	0.2	-0.1	2.4	-0.7
Exposure to tobacco smoke at home	0.3	0.3	1.8	-0.5	0.0	-0.4	-0.3	-0.4	-0.7	-0.2	-0.5	-0.2	-0.5	-0.2	-0.3	-0.3	-1.2	1.3
Glaucoma (self-reported)	0.3	0.4	2.9	-0.0	-0.6	-0.4	-0.5	-1.7	-0.6	-0.6	-0.1	-0.4	-0.1	-0.8	-0.5	-0.3	-0.4	-0.3
Medication: Blood pressure	0.3	0.5	3.2	1.0	0.5	0.6	0.5	1.0	0.2	0.5	0.5	0.6	0.5	0.3	0.5	0.5	-1.8	-0.1
Angina (self-reported)	0.3	0.3	1.2	0.6	0.8	0.5	0.3	1.1	0.6	0.6	0.4	0.6	0.3	0.6	0.6	0.4	-0.6	0.1
Whole body fat-free mass	0.3	1.6	5.3	2.3	0.8	1.1	0.4	2.3	1.0	0.8	1.1	0.9	1.1	0.4	0.8	0.9	2.3	-0.5
Handedness (chirality/laterality): Left-handed	0.3	0.4	1.0	-1.0	-0.5	-0.6	0.2	0.2	-0.4	-0.5	-0.7	-0.6	-0.8	-0.3	-0.4	-0.6	1.0	0.6
Mineral and other dietary supplements	0.3	0.5	1.1	-0.1	-0.8	-0.7	-0.8	-0.2	-1.0	-0.9	-0.4	-0.4	-0.5	-1.1	-0.8	-0.8	0.2	0.6
Whole body water mass	0.3	1.8	5.8	2.4	0.8	1.1	0.4	2.3	1.1	0.8	1.2	1.0	1.2	0.4	0.8	1.0	2.4	-0.6
Illnesses of father: High blood pressure	0.3	0.4	0.8	0.3	-0.9	-0.6	-0.1	-0.6	-0.7	-0.9	-0.2	-0.5	-0.2	-0.8	-0.9	-0.8	-0.7	-0.9
Irritability	0.3	0.4	0.8	0.5	0.8	0.8	0.6	-0.1	0.7	0.7	0.9	0.8	0.8	0.3	0.6	0.6	0.9	-0.2
Ever had prostate specific antigen (PSA) test	0.3	0.3	0.8	-0.6	-0.5	-0.5	-0.9	-0.7	-0.5	-0.6	-0.3	-0.4	-0.3	-0.7	-0.7	-0.7	-0.0	-0.1
Ever depressed for a whole week	0.3	0.3	0.8	0.2	-0.8	-0.6	-0.3	-0.9	-0.8	-0.7	-0.3	-0.5	-0.2	-0.7	-0.7	-0.3	-0.6	0.1
Myopia	0.3	0.5	2.1	0.4	-0.8	-0.4	-0.8	-1.5	-0.6	-0.8	0.3	-0.4	0.3	-0.9	-0.8	-0.6	-0.2	-0.6
Schizophrenia (2018)	0.2	0.4	0.8	-0.1	-0.9	-0.5	-0.6	-0.3	-0.7	-0.6	-0.3	-0.8	-0.3	-0.7	-0.7	-0.7	-0.9	-0.1
Ovarian Cancer	0.2	0.3	2.4	0.9	0.1	0.1	-0.3	0.5	0.0	0.0	0.3	0.5	0.2	0.0	-0.0	-0.2	-1.5	0.6
LDL Cholesterol	0.2	0.3	2.1	0.1	-0.6	-0.2	-0.6	-1.5	-0.3	-0.5	0.3	0.0	0.2	-0.8	-0.5	-0.5	0.7	0.0
BMI	0.2	1.4	3.4	-0.4	-1.3	-1.1	-1.9	0.0	-1.1	-1.1	-1.2	-0.8	-1.1	-1.6	-1.1	-0.9	1.5	-1.5
Severe depression (siblings)	0.2	0.2	2.0	0.1	0.5	0.3	0.3	-0.5	0.2	0.2	0.4	0.2	0.4	0.3	0.3	0.3	0.5	1.4
Maternal smoking around birth	0.2	0.3	0.5	-0.3	-0.5	-0.7	-0.6	0.7	-0.6	-0.6	-0.7	-0.4	-0.7	-0.6	-0.6	-0.4	0.1	-0.3
Trunk fat mass	0.2	0.9	8.4	0.6	0.4	-0.0	-0.2	2.9	-0.5	0.4	-0.7	0.4	-0.5	-0.0	0.4	0.2	-1.6	0.3
Number of incorrect matches in round	0.2	0.3	1.3	-0.5	-0.2	-0.4	-0.3	-0.5	-0.6	-0.2	-0.8	-0.6	-0.8	-0.1	-0.2	-0.4	-1.1	0.7
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	1.1	0.1	0.5	0.3	1.0	0.8	0.3	0.5	-0.1	0.3	-0.0	0.5	0.5	0.4	0.5	0.5
Arm fat percentage (right)	0.2	0.9	2.3	-0.5	-0.7	-0.8	-1.0	1.5	-1.0	-0.5	-1.4	-0.4	-1.2	-0.7	-0.5	-0.7	-0.5	-1.4
Trunk fat-free mass	0.2	1.2	5.1	2.1	0.5	0.8	0.2	1.9	0.8	0.5	1.1	0.6	1.0	0.2	0.5	0.7	2.3	-0.3
Hip circumference	0.2	0.9	5.3	1.4	0.7	0.6	0.3	2.3	0.3	0.8	0.4	1.0	0.4	0.5	0.8	0.8	-0.4	1.1
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	4.1	0.4	0.5	0.2	0.4	1.9	0.6	0.3	-0.1	0.3	-0.0	0.5	0.3	-0.1	2.0	-1.0
Happiness	0.2	0.2	1.4	-0.4	0.3	0.3	0.5	0.2	0.3	0.5	-0.1	-0.1	-0.1	0.4	0.4	0.1	0.8	-1.2
Qualifications: A levels/AS levels or equivalent	0.2	0.5	3.4	0.2	-0.8	-0.2	-0.7	-1.9	-0.3	-0.6	0.4	-0.4	0.3	-0.5	-0.5	-0.2	-0.8	0.7
Prospective memory result	0.2	0.2	2.0	-0.2	0.6	0.3	0.2	-0.3	0.5	0.3	0.1	0.2	0.2	0.4	0.3	0.2	1.4	-0.2
Arm fat mass (right)	0.2	0.7	4.1	0.1	-0.5	-0.6	-0.9	2.0	-0.8	-0.3	-1.1	-0.2	-0.9	-0.7	-0.3	-0.4	0.0	-1.1
Trunk predicted mass	0.2	1.2	5.1	2.1	0.4	0.8	0.2	1.8	0.7	0.4	1.0	0.5	1.0	0.1	0.4	0.7	2.2	-0.3
Birth weight of first child	0.2	0.3	2.2	-0.7	0.1	-0.3	-0.3	-1.5	-0.4	-0.2	-0.3	-0.2	-0.4	-0.5	-0.1	-0.2	0.7	0.7
Loud music exposure frequency	0.2	0.2	1.4	0.1	-0.3	-0.3	-0.5	-1.2	-0.3	-0.2	-0.4	0.3	-0.4	-0.3	-0.2	-0.3	-0.6	0.1
Forced vital capacity (FVC), Best measure	0.2	0.6	4.0	-0.2	0.2	-0.2	0.1	1.9	0.4	-0.0	-0.5	-0.0	-0.4	0.1	-0.0	-0.4	2.0	-0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.6	-0.1	-0.4	-0.3	-0.8	0.1	-0.1	-0.6	0.3	-0.5	0.1	-0.6	-0.6	-0.4	0.3	-0.4
Qualifications: College or University degree	0.2	0.5	1.1	-0.3	-1.0	-0.6	-0.8	-0.7	-0.5	-1.0	0.1	-1.0	-0.0	-0.8	-1.0	-0.9	-0.0	-0.3
Neck or shoulder pain in last month	0.2	0.3	1.6	0.6	0.6	0.3	0.5	-0.1	-0.2	0.5	-0.1	0.4	0.0	0.1	0.5	0.4	-1.3	1.3
Whole body fat mass	0.2	0.7	4.3	0.2	-0.3	-0.5	-0.7	2.1	-1.0	-0.1	-1.1	-0.1	-1.0	-0.6	-0.2	-0.4	-1.4	0.0
Pulse rate, automated reading	0.2	0.6	4.5	-0.0	0.4	0.4	0.4	2.1	0.7	0.7	-0.3	0.2	-0.1	0.9	0.7	0.6	0.5	1.1
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	0.8	-0.6	-0.6	-0.5	-0.8	-0.9	-0.2	-0.5	-0.6	-0.6	-0.7	-0.2	-0.4	-0.5	0.0	-0.5
Hypertension (Self-reported)	0.2	0.4	0.9	0.6	-0.9	-0.4	-0.9	-0.1	-0.6	-0.8	0.1	-0.4	0.1	-0.9	-0.9	-0.5	-0.9	-0.7
Smoking status: Previous	0.2	0.3	0.7	0.7	0.7	0.7	0.3	-0.4	0.8	0.6	0.7	0.4	0.7	0.5	0.6	0.4	0.2	-0.3
Arm fat percentage (left)	0.2	1.0	2.8	-0.6	-0.7	-0.9	-1.1	1.7	-1.1	-0.5	-1.6	-0.4	-1.4	-0.8	-0.5	-0.7	-0.9	-0.9
Ever had bowel cancer screening	0.2	0.2	1.7	-0.1	-0.7	-0.2	-0.3	-0.7	-0.3	-0.4	0.2	-0.3	0.1	-0.4	-0.4	0.1	-1.3	0.1
Qualifications: nursing, teaching	0.2	0.4	1.3	0.8	0.3	0.6	0.3	-0.2	0.5	0.3	1.1	0.4	1.1	0.5	0.3	0.6	-0.6	0.4
Commuting to job workplace: Walk	0.2	0.2	1.3	0.1	-0.1	-0.1	-0.4	-0.4	-0.1	-0.2	0.1	0.1	0.0	-0.1	-0.1	-0.2	-1.1	1.1
Smoking status: Current	0.2	0.3	0.5	-0.5	-0.5	-0.7	-0.4	-0.6	-0.7	-0.6	-0.6	-0.7	-0.5	-0.6	-0.6	-0.3	-0.3	-0.7
Arm fat mass (left)	0.2	0.9	3.8	-0.0	-0.7	-0.8	-1.1	2.0	-1.0	-0.5	-1.2	-0.4	-1.1	-0.9	-0.5	-0.6	-0.2	-1.1
Basal metabolic rate	0.2	1.4	5.9	2.2	0.7	0.9	0.3	2.4	0.8	0.7	0.9	0.9	0.9	0.3	0.7	0.8	1.8	-0.5
Vascular/heart problems diagnosed by doctor	0.2	0.6	3.5	-1.9	-0.3	-0.7	-0.3	-0.8	-0.4	-0.2	-1.2	-0.6	-1.2	0.0	-0.1	-0.5	0.3	0.7
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	0.8	-0.4	-0.4	-0.6	-0.3	0.1	-0.7	-0.6	-0.4	-0.3	-0.5	-0.6	-0.6	-0.7	-0.9	0.2
Basal cell carcinoma (self-reported)	0.2	0.2	1.6	-1.3	0.1	-0.2	0.3	-0.3	-0.2	0.1	-0.6	-0.5	-0.5	0.1	0.1	0.1	0.8	0.4
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	1.2	0.6	0.3	0.4	0.4	1.1	0.3	0.4	0.3	0.4	0.3	0.4	0.4	0.3	-0.3	0.3
Pack years of smoking	0.2	0.3	1.3	-0.0	-0.5	-0.4	-0.7	-0.1	-0.4	-0.6	-0.1	0.0	-0.1	-0.6	-0.6	-0.7	1.2	-0.8
Bipolar Disorder (2011)	0.1	0.1	0.6	0.1	-0.2	0.0	0.0	-0.8	0.0	-0.2	0.0	0.3	0.3	-0.1	-0.1	0.1	0.3	0.5
Smoking Status	0.1	0.2	1.8	0.4	-0.1	-0.1	-0.3	-1.3	-0.0	-0.3	0.5	0.0	0.5	-0.3	-0.4	0.1	-0.2	-0.2
Lung FEV1/FVC ratio	0.1	0.4	3.0	0.8	0.1	0.5	0.2	-0.1	0.5	0.4	0.6	0.5	0.6	-0.1	0.3	0.5	1.7	-1.0
Hair Pigment	0.1	1.6	3.2	-0.7	1.5	1.0	1.5	1.4	1.5	1.5	0.1	0.5	0.3	1.6	1.5	1.3	1.8	-1.3
Average weekly spirits intake	0.1	0.1	0.5	-0.1	0.2	0.2	0.1	0.1	0.1	0.2	0.3	0.1	0.3	0.3	0.2	0.6	-0.0	0.7
Supplements: Zinc	0.1	0.1	0.3	-0.4	0.1	0.0	0.3	-0.5	-0.0	0.2	-0.1	0.3	-0.1	0.3	0.2	0.1	-0.5	0.1
High blood pressure	0.1	0.3	1.1	1.1	-0.5	-0.1	-0.5	0.2	-0.3	-0.5	0.4	-0.0	0.4	-0.6	-0.5	-0.2	-1.0	-0.7
Multivitamins +/- minerals	0.1	0.1	0.3	-0.2	0.3	0.1	0.4	-0.4	0.4	0.1	0.0	0.2	-0.0	0.5	0.1	0.1	-0.5	0.3
Diverticular disease/diverticulitis (self-reported)	0.1	0.2	0.9	0.3	0.1	0.3	0.4	-0.9	0.2	0.0	0.5	0.4	0.5	0.3	0.1	0.1	-0.6	-0.5
Waist circumference	0.1	0.3	1.0	0.7	-0.5	-0.4	-0.8	0.6	-0.7	-0.5	-0.4	0.0	-0.3	-1.0	-0.5	-0.4	0.1	-0.9
Nervous feelings	0.1	0.2	0.7	0.2	0.2	0.2	0.5	0.6	0.4	0.2	0.1	0.4	0.2	0.4	0.2	0.3	0.8	-0.9
Forced vital capacity (FVC)	0.1	0.6	3.8	0.5	0.6	0.2	0.5	2.0	0.7	0.3	-0.0	0.3	0.0	0.5	0.3	-0.0	1.4	-0.7
Financial difficulties in last 2 years	0.1	0.2	0.6	-0.6	0.2	-0.2	0.3	0.5	-0.3	0.2	-0.8	-0.2	-0.6	0.2	0.1	0.1	0.1	-0.7
Illnesses of siblings	0.1	0.2	1.0	0.2	-0.1	0.2	-0.1	-0.8	0.2	-0.0	0.4	-0.1	0.3	-0.3	-0.0	0.3	1.0	-0.2
Weight	0.1	0.6	5.9	1.3	0.1	0.2	-0.3	2.4	-0.2	0.2	-0.1	0.3	0.0	-0.2	0.2	0.2	0.3	-0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	1.2	-0.6	0.1	-0.3	0.5	-0.0	-0.5	-0.1	-0.7	-0.4	-0.6	-0.1	-0.1	-0.2	-0.2	-1.1
Blood clot in the leg (DVT)	0.1	0.1	1.3	0.4	0.2	0.1	0.3	1.1	0.1	0.2	-0.1	0.1	-0.0	0.2	0.2	0.1	-0.2	0.1
Arm fat-free mass (right)	0.1	0.5	2.8	1.5	0.1	0.2	-0.2	1.7	0.1	0.1	0.2	0.1	0.2	-0.3	0.1	0.2	1.2	-0.2
Worry too long after embarrassment	0.1	0.2	0.5	0.4	0.3	0.5	0.7	-0.6	0.4	0.4	0.6	0.3	0.7	0.4	0.3	0.3	-0.5	0.4
Emphysema/chronic bronchitis	0.1	0.1	1.4	0.0	0.0	0.2	0.4	0.2	0.4	0.3	0.1	0.3	0.1	0.2	0.2	0.2	1.2	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.2	1.5	-0.0	0.2	0.3	0.4	-1.2	0.3	0.3	0.3	0.1	0.2	0.2	0.2	0.3	0.3	-0.1
Arm predicted mass (right)	0.1	0.4	2.3	1.5	0.1	0.2	-0.4	1.4	0.1	0.0	0.2	0.1	0.2	-0.4	0.0	0.1	1.1	-0.5
Alcohol intake frequency.	0.1	0.3	2.2	0.1	-0.5	-0.5	-0.2	1.5	-0.4	-0.5	-0.7	0.1	-0.6	-0.3	-0.4	-0.3	-0.7	0.1
Average weekly red wine intake	0.1	0.2	0.5	0.2	0.3	0.4	-0.2	-0.5	0.6	0.3	0.6	0.1	0.6	0.3	0.3	0.5	0.7	0.5
Friendships satisfaction	0.1	0.2	2.3	0.2	0.1	0.2	0.2	-0.2	-0.0	0.2	0.2	0.0	0.2	0.0	0.2	0.2	-0.3	-1.5
Medication for cholesterol	0.1	0.2	1.8	-0.4	0.4	0.1	0.1	-1.4	0.2	0.4	-0.2	-0.2	-0.2	0.4	0.4	0.3	-0.2	0.4
Guilty feelings	0.1	0.1	0.7	-0.8	0.1	0.1	0.4	-0.2	0.4	0.3	-0.1	0.0	0.0	0.3	0.2	0.2	0.5	-0.1
Hearing aid user	0.1	0.1	0.4	0.2	-0.3	0.1	-0.2	-0.7	-0.1	-0.1	0.2	0.1	0.2	-0.3	-0.1	-0.0	0.2	0.2
Mother’s age at death	0.1	0.2	0.5	-0.4	0.4	0.3	0.7	-0.3	0.3	0.5	-0.0	-0.2	0.0	0.6	0.6	0.3	0.0	-0.7
Financial situation satisfaction	0.1	0.1	0.5	-0.4	0.4	0.0	0.0	0.4	0.1	0.2	-0.1	-0.2	-0.1	0.1	0.2	0.1	-0.3	-0.7
Ever smoked	0.1	0.2	1.1	0.1	-0.5	-0.2	-0.3	-1.1	-0.1	-0.3	-0.1	-0.6	-0.0	-0.2	-0.3	-0.2	-0.6	-0.8
Arm fat-free mass (left)	0.1	0.6	2.8	1.7	-0.2	0.2	-0.4	1.5	0.0	-0.1	0.3	0.0	0.3	-0.4	-0.1	0.0	1.5	-0.9
Commuting to job workplace: Cycle	0.1	0.1	0.3	0.2	0.4	0.3	0.5	-0.2	0.3	0.3	0.2	0.1	0.2	0.3	0.3	0.2	0.6	-0.1
Arm predicted mass (left)	0.1	0.6	3.0	1.7	-0.0	0.3	-0.2	1.6	0.2	0.1	0.4	0.2	0.4	-0.2	0.1	0.2	1.4	-0.9
Current tobacco smoking	0.0	0.1	0.3	-0.2	-0.1	-0.3	0.0	-0.2	-0.3	-0.2	-0.2	-0.3	-0.2	-0.2	-0.3	0.0	0.0	-0.5
Past tobacco smoking	0.0	0.1	0.6	-0.2	-0.0	-0.0	0.2	0.8	-0.1	0.0	-0.1	0.2	-0.1	0.2	0.0	0.0	0.3	0.6
Medication: Seretide 50 evohaler	0.0	0.0	0.1	-0.1	-0.1	-0.1	0.1	0.4	-0.2	0.1	-0.4	-0.2	-0.4	0.1	0.1	-0.0	-0.1	0.4

Hub : Genes

RAB5C

Models

Trait associations