[Hub]/) : Traits : Standing height :

chr4:16,767,708-18,507,692

Best TWAS P=1.54e-158 · Best GWAS P=5.99e-142 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FAM184B 0.14 0.25 enet 21 0.24 2.0e-28 -7.266 7.2 6.3e-13 -0.14 1.00 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex LAP3 0.05 0.06 lasso 2 0.05 4.8e-07 -6.060 -6.5 6.5e-11 0.11 1.00 0.00 FALSE
3 CommonMind Brain Pre-frontal Cortex MED28 0.07 0.09 enet 9 0.11 7.1e-13 -7.339 8.3 7.6e-17 -0.18 1.00 0.00 FALSE
4 GTEx Adipose Subcutaneous DCAF16 0.21 0.15 lasso 3 0.17 5.1e-14 16.956 16.4 8.6e-61 -0.24 1.00 0.00 FALSE
5 GTEx Adipose Visceral Omentum DCAF16 0.19 0.06 enet 10 0.11 3.9e-06 16.956 18.5 2.2e-76 -0.35 0.34 0.37 TRUE
6 GTEx Artery Aorta DCAF16 0.10 0.01 enet 6 0.02 4.7e-02 -23.296 26.8 1.5e-158 -0.81 0.07 0.70 TRUE
7 GTEx Artery Tibial DCAF16 0.16 0.16 lasso 5 0.13 1.5e-10 18.843 20.9 5.2e-97 -0.36 1.00 0.00 FALSE
8 GTEx Breast Mammary Tissue DCAF16 0.12 0.08 lasso 4 0.10 6.4e-06 17.073 21.4 5.1e-102 -0.52 0.11 0.73 TRUE
9 GTEx Breast Mammary Tissue (Male) DCAF16 0.24 0.03 enet 18 -0.01 4.4e-01 -22.642 24.3 8.3e-131 -0.76 0.04 0.65 FALSE
10 GTEx Breast Mammary Tissue (Female) DCAF16 0.16 0.13 lasso 2 0.06 7.8e-03 16.956 16.9 2.3e-64 -0.27 0.06 0.10 FALSE
11 GTEx Cells Transformed fibroblasts LAP3 0.20 0.12 lasso 6 0.13 3.0e-10 -7.271 -7.0 3.1e-12 0.13 1.00 0.00 FALSE
12 GTEx Colon Transverse MED28 0.13 0.05 lasso 3 0.02 5.8e-02 -6.107 6.1 1.0e-09 -0.11 0.20 0.04 FALSE
13 GTEx Esophagus Mucosa DCAF16 0.10 0.02 lasso 4 0.02 8.3e-03 17.073 18.7 3.7e-78 -0.37 0.14 0.37 FALSE
14 GTEx Esophagus Muscularis DCAF16 0.16 0.14 lasso 3 0.14 9.3e-09 16.956 16.9 6.8e-64 -0.27 0.99 0.00 FALSE
15 GTEx Muscle Skeletal MED28 0.05 0.03 enet 8 0.02 3.1e-03 -7.171 7.3 3.8e-13 -0.14 0.56 0.02 FALSE
16 GTEx Nerve Tibial DCAF16 0.16 0.14 lasso 3 0.14 2.8e-10 16.956 19.0 1.3e-80 -0.37 0.99 0.01 FALSE
17 GTEx Pituitary DCAF16 0.27 0.20 enet 15 0.19 1.3e-05 16.956 15.6 6.3e-55 -0.38 0.08 0.27 FALSE
18 GTEx Skin Not Sun Exposed Suprapubic DCAF16 0.16 0.08 lasso 5 0.12 4.4e-07 16.919 18.9 1.2e-79 -0.35 0.64 0.04 TRUE
19 GTEx Skin Sun Exposed Lower leg QDPR 0.11 0.04 enet 22 0.08 4.8e-07 0.519 5.8 8.6e-09 -0.29 0.27 0.42 TRUE
20 GTEx Skin Sun Exposed Lower leg DCAF16 0.14 0.12 enet 14 0.12 5.4e-10 17.073 18.5 1.3e-76 -0.28 1.00 0.00 FALSE
21 GTEx Spleen LAP3 0.15 0.16 lasso 3 0.15 1.3e-04 -5.077 -6.2 4.6e-10 0.13 0.39 0.05 FALSE
22 GTEx Spleen DCAF16 0.35 0.02 lasso 5 0.11 8.5e-04 16.956 25.2 1.2e-140 -0.66 0.04 0.63 FALSE
23 GTEx Stomach DCAF16 0.21 0.04 lasso 6 0.02 5.6e-02 18.752 20.4 1.8e-92 -0.26 0.19 0.05 TRUE
24 GTEx Testis LAP3 0.28 0.19 lasso 3 0.19 5.1e-09 -6.071 -6.4 1.6e-10 0.11 1.00 0.00 FALSE
25 GTEx Thyroid DCAF16 0.11 0.02 lasso 5 0.03 2.3e-03 16.956 24.1 2.6e-128 -0.54 0.20 0.65 FALSE
26 GTEx Whole Blood LAP3 0.06 0.02 enet 7 0.02 1.1e-02 -6.069 -6.2 6.3e-10 0.12 0.69 0.02 FALSE
27 NTR Blood LAP3 0.06 0.07 lasso 5 0.07 1.6e-22 -6.071 -6.0 2.6e-09 0.10 1.00 0.00 FALSE
28 NTR Blood MED28 0.09 0.18 lasso 2 0.18 3.7e-54 -7.171 7.4 1.5e-13 -0.16 1.00 0.00 FALSE
29 ROSMAP Brain Pre-frontal Cortex LAP3 0.12 0.09 lasso 6 0.10 1.9e-12 -6.001 -6.0 2.7e-09 0.10 1.00 0.00 FALSE
30 ROSMAP Brain Pre-frontal Cortex FAM184B 0.17 0.14 enet 31 0.18 5.1e-23 -7.339 -10.9 7.0e-28 0.26 1.00 0.00 TRUE
31 ROSMAP Brain Pre-frontal Cortex MED28 0.02 0.01 bslmm 411 0.00 1.9e-01 -7.403 10.3 9.0e-25 -0.30 0.22 0.03 FALSE
32 ROSMAP Brain Pre-frontal Cortex DCAF16 0.04 0.02 bslmm 379 0.01 3.9e-02 -22.680 22.5 1.8e-112 -0.83 0.03 0.88 FALSE
33 YFS Blood DCAF16 0.02 0.02 lasso 1 0.01 1.1e-04 18.843 18.8 3.4e-79 -0.25 0.84 0.03 FALSE
34 The Cancer Genome Atlas Breast Invasive Carcinoma MED28 0.02 0.01 enet 4 0.01 4.0e-03 -5.784 5.8 6.9e-09 -0.11 0.04 0.72 FALSE
35 The Cancer Genome Atlas Breast Invasive Carcinoma NCAPG 0.03 0.04 enet 5 0.04 8.1e-09 0.089 -8.5 1.6e-17 0.55 0.95 0.04 TRUE
36 The Cancer Genome Atlas Colon Adenocarcinoma NCAPG 0.08 0.04 blup 34 0.09 1.1e-05 -22.700 -19.9 4.5e-88 0.84 0.06 0.91 FALSE
37 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma FAM184B 0.02 0.03 lasso 2 0.02 2.6e-03 -7.723 -7.8 7.4e-15 0.16 0.24 0.03 FALSE
38 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma LAP3 0.09 0.06 lasso 2 0.05 3.3e-06 -6.107 -6.2 4.7e-10 0.13 0.35 0.63 FALSE
39 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma NCAPG 0.14 0.07 lasso 3 0.07 5.2e-08 -22.680 -22.0 1.4e-107 0.84 0.99 0.00 FALSE
40 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LAP3 0.04 0.08 enet 5 0.08 1.9e-09 -6.001 -6.1 1.0e-09 0.10 0.08 0.92 FALSE
41 The Cancer Genome Atlas Brain Lower Grade Glioma DCAF16 0.09 0.02 lasso 3 0.04 5.2e-05 18.843 25.8 9.3e-147 -0.64 0.04 0.91 FALSE
42 The Cancer Genome Atlas Brain Lower Grade Glioma LAP3 0.03 0.03 blup 36 0.03 2.4e-04 -5.784 -6.5 9.5e-11 0.11 0.08 0.82 FALSE
43 The Cancer Genome Atlas Brain Lower Grade Glioma MED28 0.07 0.06 lasso 2 0.06 4.5e-07 -7.201 6.7 2.8e-11 -0.12 0.04 0.96 FALSE
44 The Cancer Genome Atlas Brain Lower Grade Glioma NCAPG 0.02 0.03 lasso 1 0.02 9.0e-04 -22.700 -22.7 4.5e-114 0.88 0.03 0.54 FALSE
45 The Cancer Genome Atlas Liver Hepatocellular Carcinoma MED28 0.08 0.05 blup 34 0.05 2.9e-03 -7.189 7.6 3.8e-14 -0.17 0.02 0.75 FALSE
46 The Cancer Genome Atlas Lung Adenocarcinoma MED28 0.02 0.01 blup 34 0.01 8.5e-03 -7.271 7.2 8.9e-13 -0.14 0.03 0.81 FALSE
47 The Cancer Genome Atlas Lung Adenocarcinoma NCAPG 0.06 0.02 blup 34 0.04 1.0e-05 -22.700 -13.1 5.1e-39 0.68 0.13 0.05 FALSE
48 The Cancer Genome Atlas Lung Squamous Cell Carcinoma LAP3 0.02 0.02 lasso 4 0.01 2.2e-02 -7.201 -7.2 6.0e-13 0.14 0.02 0.79 FALSE
49 The Cancer Genome Atlas Lung Squamous Cell Carcinoma MED28 0.03 0.02 blup 34 0.03 2.3e-04 -6.071 6.7 1.7e-11 -0.12 0.04 0.93 FALSE
50 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma LAP3 0.04 0.02 blup 36 0.02 1.5e-02 -7.210 -6.6 4.5e-11 0.14 0.01 0.72 FALSE
51 The Cancer Genome Atlas Pancreatic Adenocarcinoma MED28 0.10 0.12 enet 8 0.12 1.6e-05 -7.266 7.1 1.4e-12 -0.12 0.03 0.94 FALSE
52 The Cancer Genome Atlas Prostate Adenocarcinoma DCAF16 0.04 0.04 blup 31 0.04 2.2e-05 16.956 23.7 4.3e-124 -0.58 0.26 0.26 FALSE
53 The Cancer Genome Atlas Prostate Adenocarcinoma MED28 0.06 0.05 enet 3 0.07 1.7e-07 -7.158 6.4 1.3e-10 -0.14 0.03 0.97 FALSE
54 The Cancer Genome Atlas Prostate Adenocarcinoma NCAPG 0.02 0.02 blup 34 0.02 3.4e-03 -21.500 -19.6 1.1e-85 0.76 0.01 0.88 FALSE
55 The Cancer Genome Atlas Stomach Adenocarcinoma LAP3 0.07 0.03 blup 36 0.06 5.3e-05 -5.107 -7.3 2.6e-13 0.15 0.03 0.97 FALSE
56 The Cancer Genome Atlas Testicular Germ Cell Tumors MED28 0.08 0.05 lasso 3 0.05 8.7e-03 -6.069 6.8 1.4e-11 -0.12 0.02 0.69 FALSE
57 The Cancer Genome Atlas Thyroid Carcinoma DCAF16 0.07 0.04 blup 31 0.07 4.9e-07 18.752 24.4 6.5e-132 -0.65 0.15 0.77 FALSE
58 The Cancer Genome Atlas Thyroid Carcinoma MED28 0.03 0.03 blup 34 0.02 3.4e-03 -7.158 7.0 1.7e-12 -0.14 0.02 0.68 FALSE