Best TWAS P=8.89e-09 · Best GWAS P=2.37e-11 conditioned to 0.000378
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | TRMT10A | 0.35 | 0.26 | lasso | 9 | 0.26 | 4.8e-12 | 4.5 | 5.5 | 3.1e-08 | 0.59 | 0.40 | 0.60 | FALSE |
| 2 | METSIM | Adipose | TRMT10A | 0.05 | 0.00 | bslmm | 512 | 0.01 | 2.1e-02 | 6.2 | 5.3 | 1.1e-07 | 0.53 | 0.06 | 0.57 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | MTTP | 0.02 | 0.01 | blup | 75 | 0.01 | 7.2e-03 | 4.6 | -5.8 | 8.9e-09 | -0.76 | 0.09 | 0.49 | TRUE |