Best TWAS P=2.94e-17 · Best GWAS P=1.95e-16 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Muscle Skeletal | TANK | 0.07 | 0.06 | lasso | 2 | 0.04 | 8.9e-05 | -8.2 | 8.4 | 2.9e-17 | -0.99 | 0.00 | 1.00 | TRUE |
2 | METSIM | Adipose | AC009299.3 | 0.06 | 0.03 | lasso | 4 | 0.04 | 6.5e-07 | -8.2 | 7.5 | 4.4e-14 | -0.90 | 0.00 | 1.00 | FALSE |
3 | NTR | Blood | TANK | 0.02 | 0.02 | lasso | 3 | 0.02 | 8.7e-07 | -8.2 | 8.2 | 3.4e-16 | -1.00 | 0.00 | 1.00 | FALSE |
4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | RBMS1 | 0.03 | 0.01 | blup | 118 | 0.02 | 4.6e-03 | -4.1 | 5.3 | 1.5e-07 | 0.01 | 0.04 | 0.74 | TRUE |