Best TWAS P=7.05e-11 · Best GWAS P=3.43e-08 conditioned to 0.000808
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | JMJD1C | 0.09 | 0.01 | enet | 18 | 0.07 | 8.6e-06 | -4.4 | -5.4 | 5.4e-08 | -0.42 | 0.18 | 0.55 | FALSE |
| 2 | GTEx | Testis | JMJD1C-AS1 | 0.22 | 0.08 | enet | 23 | 0.10 | 3.7e-05 | -4.6 | -6.5 | 7.1e-11 | -0.37 | 0.12 | 0.83 | TRUE |
| 3 | GTEx | Thyroid | NRBF2 | 0.11 | 0.05 | lasso | 3 | 0.07 | 2.5e-06 | -4.3 | -5.2 | 1.7e-07 | -0.53 | 0.15 | 0.81 | FALSE |
| 4 | The Cancer Genome Atlas | Glioblastoma Multiforme | JMJD1C | 0.11 | 0.02 | blup | 87 | 0.05 | 1.4e-02 | 4.3 | -5.5 | 3.4e-08 | -0.53 | 0.03 | 0.34 | FALSE |
| 5 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | LOC84989 | 0.10 | 0.05 | blup | 19 | 0.04 | 7.7e-03 | -5.1 | -5.8 | 5.4e-09 | -0.44 | 0.00 | 0.66 | FALSE |
| 6 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | NRBF2 | 0.18 | 0.13 | enet | 11 | 0.08 | 2.5e-04 | 4.3 | -5.5 | 3.0e-08 | -0.73 | 0.06 | 0.78 | FALSE |