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chr10:102,853,189-104,956,035

Best TWAS P=4.08e-13 · Best GWAS P=4.49e-13 conditioned to 0.254

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
9	The Cancer Genome Atlas	Brain Lower Grade Glioma	NPM3	0.02	0.03	lasso	3	0.02	9.2e-04	7.1	-7.3	4.1e-13	-0.94	0.00	0.87	TRUE
2	GTEx	Liver	ACTR1A	0.15	0.00	lasso	10	0.00	4.6e-01	5.1	6.4	1.9e-10	0.34	0.08	0.06	TRUE
10	The Cancer Genome Atlas	Testicular Germ Cell Tumors	C10orf76	0.19	0.20	lasso	1	0.18	4.6e-07	7.1	7.1	1.1e-12	0.93	0.01	0.99	FALSE
4	GTEx	Testis	NPM3	0.13	0.15	lasso	3	0.13	2.5e-06	7.1	-7.1	1.2e-12	-0.94	0.01	0.98	FALSE
1	CommonMind	Brain Pre-frontal Cortex	NPM3	0.03	0.01	lasso	2	0.03	1.2e-04	7.1	-6.9	4.8e-12	-0.82	0.01	0.96	FALSE
3	GTEx	Pancreas	NPM3	0.20	0.15	lasso	4	0.07	5.4e-04	7.1	-6.9	5.8e-12	-0.93	0.02	0.97	FALSE
7	The Cancer Genome Atlas	Colon Adenocarcinoma	C10orf76	0.16	0.07	lasso	2	0.06	2.1e-04	5.3	6.1	1.2e-09	0.53	0.04	0.67	FALSE
8	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	NPM3	0.04	0.02	blup	22	0.02	1.8e-03	7.2	-5.6	2.2e-08	-0.78	0.00	0.66	FALSE
6	ROSMAP	Brain Pre-frontal Cortex	NPM3	0.05	0.01	blup	257	0.04	1.5e-05	7.1	-5.3	1.2e-07	-0.74	0.02	0.96	FALSE
5	METSIM	Adipose	HPS6	0.05	0.03	bslmm	284	0.02	1.6e-03	5.4	5.2	2.5e-07	0.36	0.12	0.32	FALSE