Best TWAS P=5.36e-10 · Best GWAS P=7.96e-08 conditioned to 0.801
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | FARP1 | 0.10 | 0.05 | enet | 5 | 0.05 | 1.4e-06 | 5.3 | -5.6 | 1.7e-08 | 0.71 | 0.02 | 0.98 | FALSE |
2 | GTEx | Adipose Subcutaneous | STK24 | 0.18 | 0.06 | lasso | 8 | 0.08 | 2.4e-07 | 5.2 | 6.2 | 5.4e-10 | -0.84 | 0.02 | 0.98 | TRUE |
3 | GTEx | Esophagus Mucosa | FARP1-AS1 | 0.11 | 0.03 | lasso | 2 | 0.04 | 1.7e-03 | 5.3 | 5.2 | 1.7e-07 | -0.58 | 0.02 | 0.98 | FALSE |
4 | NTR | Blood | FARP1 | 0.02 | 0.01 | lasso | 3 | 0.01 | 4.3e-04 | 4.8 | 5.4 | 6.6e-08 | -0.57 | 0.05 | 0.93 | FALSE |