[Hub]/) : Traits : Qualifications: None of the above : ← →

chr5:59,193,824-61,156,570

Best TWAS P=1.9e-17 · Best GWAS P=3.23e-17 conditioned to 0.696

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
15	GTEx	Skin Not Sun Exposed Suprapubic	ELOVL7	0.14	0.09	lasso	3	0.08	6.3e-05	8.4	-8.5	1.9e-17	-0.90	0.01	0.97	TRUE
2	CommonMind	Brain Pre-frontal Cortex	ELOVL7	0.04	0.03	blup	355	0.03	1.4e-04	-6.8	8.4	4.5e-17	0.82	0.12	0.87	TRUE
30	The Cancer Genome Atlas	Prostate Adenocarcinoma	ERCC8	0.06	0.04	lasso	1	0.02	2.3e-03	8.4	8.4	3.2e-17	1.00	0.00	0.99	FALSE
24	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ERCC8	0.07	0.04	lasso	3	0.04	4.7e-05	8.4	8.2	2.8e-16	0.99	0.00	1.00	FALSE
23	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ELOVL7	0.06	0.07	blup	66	0.07	2.1e-08	8.4	-8.1	6.6e-16	-0.90	0.01	0.99	FALSE
27	The Cancer Genome Atlas	Lung Adenocarcinoma	ERCC8	0.04	0.01	blup	39	0.01	8.1e-03	4.3	8.0	8.6e-16	0.89	0.01	0.81	FALSE
6	GTEx	Brain Cerebellar Hemisphere	GNL3LP1	0.21	0.17	lasso	10	0.12	6.2e-04	-7.7	-7.9	2.6e-15	-0.79	0.23	0.58	FALSE
10	GTEx	Cells Transformed fibroblasts	GNL3LP1	0.05	0.10	lasso	2	0.09	1.4e-07	-7.8	-7.8	6.3e-15	-0.76	0.44	0.56	FALSE
8	GTEx	Brain Hippocampus	GNL3LP1	0.51	0.04	enet	2	0.14	4.1e-04	-7.8	-7.8	8.3e-15	-0.73	0.06	0.12	FALSE
13	GTEx	Pancreas	SMIM15	0.10	0.03	enet	22	0.05	3.8e-03	8.4	-7.6	2.4e-14	-0.71	0.03	0.71	FALSE
12	GTEx	Esophagus Mucosa	GNL3LP1	0.05	0.07	lasso	3	0.05	3.2e-04	-7.4	-7.6	2.7e-14	-0.80	0.34	0.26	FALSE
20	The Cancer Genome Atlas	Breast Invasive Carcinoma	ERCC8	0.09	0.06	enet	7	0.06	8.5e-13	8.4	7.4	1.8e-13	0.91	0.00	1.00	FALSE
9	GTEx	Cells Transformed fibroblasts	ERCC8	0.08	0.04	lasso	6	0.05	1.7e-04	8.4	7.3	2.5e-13	0.91	0.01	0.98	FALSE
11	GTEx	Esophagus Mucosa	ERCC8	0.16	0.06	enet	11	0.09	1.3e-06	8.4	7.3	3.7e-13	0.86	0.01	0.99	FALSE
1	CommonMind	Brain Pre-frontal Cortex	DEPDC1B	0.04	0.00	blup	341	0.03	3.4e-04	-7.3	-7.1	1.7e-12	-0.63	0.08	0.71	FALSE
22	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ERCC8	0.03	0.01	enet	9	0.02	9.2e-04	8.4	7.1	1.8e-12	0.87	0.00	0.97	FALSE
17	GTEx	Thyroid	GNL3LP1	0.10	0.04	enet	16	0.02	1.0e-02	-7.8	-6.8	7.9e-12	-0.73	0.13	0.79	FALSE
18	METSIM	Adipose	ERCC8	0.07	0.08	blup	317	0.08	8.9e-12	-8.1	6.8	8.8e-12	0.78	0.04	0.96	FALSE
28	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ERCC8	0.06	0.03	blup	39	0.03	2.8e-04	4.3	6.8	1.1e-11	0.84	0.09	0.70	FALSE
14	GTEx	Pancreas	GNL3LP1	0.08	0.05	lasso	5	0.04	6.7e-03	-6.8	-6.5	8.7e-11	-0.67	0.15	0.25	FALSE
16	GTEx	Stomach	ELOVL7	0.15	0.14	enet	14	0.16	4.7e-08	4.8	-6.5	8.9e-11	-0.64	0.27	0.62	FALSE
7	GTEx	Brain Cerebellum	GNL3LP1	0.18	0.18	enet	9	0.11	3.2e-04	-7.4	-6.4	1.1e-10	-0.71	0.10	0.71	FALSE
31	The Cancer Genome Atlas	Thyroid Carcinoma	ERCC8	0.11	0.03	blup	39	0.04	4.3e-05	8.4	6.3	2.4e-10	0.84	0.00	1.00	FALSE
19	ROSMAP	Brain Pre-frontal Cortex	DEPDC1B	0.05	0.01	lasso	9	0.01	4.8e-03	5.4	-6.3	2.7e-10	-0.56	0.24	0.04	FALSE
29	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ERCC8	0.11	0.07	enet	6	0.09	2.0e-04	4.6	6.3	2.8e-10	0.81	0.02	0.90	FALSE
26	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	ELOVL7	0.19	0.10	enet	17	0.17	1.7e-08	2.3	-6.1	7.9e-10	-0.79	0.01	0.99	FALSE
4	GTEx	Adipose Visceral Omentum	GNL3LP1	0.09	0.02	enet	23	0.06	7.5e-04	6.6	-5.8	4.9e-09	-0.56	0.11	0.18	FALSE
5	GTEx	Artery Tibial	ERCC8	0.09	0.01	lasso	5	0.00	2.4e-01	-1.4	5.8	7.5e-09	0.57	0.02	0.66	FALSE
3	CommonMind	Brain Pre-frontal Cortex	ERCC8	0.11	0.08	lasso	9	0.10	8.9e-12	4.9	5.5	3.6e-08	0.51	0.93	0.07	FALSE
21	The Cancer Genome Atlas	Colon Adenocarcinoma	ELOVL7	0.06	0.08	lasso	1	0.02	1.4e-02	5.4	-5.4	6.9e-08	-0.52	0.17	0.35	FALSE
25	The Cancer Genome Atlas	Brain Lower Grade Glioma	DEPDC1B	0.05	0.06	lasso	3	0.06	4.0e-07	4.7	5.3	1.4e-07	0.51	0.95	0.03	FALSE