[Hub]/) : Traits : Qualifications: A levels/AS levels or equivalent :

chr5:59,353,199-61,156,570

Best TWAS P=6.28e-09 · Best GWAS P=5.85e-09 conditioned to 0.163

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ELOVL7 0.04 0.03 blup 355 0.03 1.4e-04 4.5 -5.6 2.6e-08 0.82 0.06 0.94 FALSE
2 GTEx Brain Cerebellar Hemisphere GNL3LP1 0.21 0.17 lasso 10 0.12 6.2e-04 5.3 5.7 1.6e-08 -0.78 0.12 0.78 FALSE
3 GTEx Brain Hippocampus GNL3LP1 0.51 0.04 enet 2 0.14 4.1e-04 5.2 5.2 1.6e-07 -0.73 0.05 0.34 FALSE
4 GTEx Cells Transformed fibroblasts ERCC8 0.08 0.04 lasso 6 0.05 1.7e-04 -5.6 -5.4 5.5e-08 0.91 0.02 0.97 FALSE
5 GTEx Cells Transformed fibroblasts GNL3LP1 0.05 0.10 lasso 2 0.09 1.4e-07 5.3 5.3 1.2e-07 -0.76 0.11 0.89 FALSE
6 GTEx Esophagus Mucosa ERCC8 0.16 0.06 enet 11 0.09 1.3e-06 -5.5 -5.8 7.1e-09 0.87 0.02 0.98 FALSE
7 GTEx Pancreas SMIM15 0.10 0.03 enet 22 0.05 3.8e-03 -5.6 5.1 2.7e-07 -0.71 0.04 0.58 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic ELOVL7 0.14 0.09 lasso 3 0.08 6.3e-05 -5.5 5.7 9.3e-09 -0.90 0.02 0.93 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ERCC8 0.07 0.04 lasso 3 0.04 4.7e-05 -5.6 -5.6 2.0e-08 0.99 0.00 0.99 FALSE
10 The Cancer Genome Atlas Lung Adenocarcinoma ERCC8 0.04 0.01 blup 39 0.01 8.1e-03 -3.7 -5.8 6.3e-09 0.90 0.01 0.66 TRUE
11 The Cancer Genome Atlas Prostate Adenocarcinoma ERCC8 0.06 0.04 lasso 1 0.02 2.3e-03 -5.6 -5.6 1.9e-08 1.00 0.00 0.97 FALSE