[Hub]/) : Traits : Qualifications: O levels/GCSEs or equivalent :

chr12:122,713,991-124,591,385

Best TWAS P=1.35e-11 · Best GWAS P=7.08e-11 conditioned to 0.621

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous CDK2AP1 0.20 0.18 lasso 11 0.19 1.0e-15 6.0 -5.8 5.7e-09 -0.93 0.20 0.80 FALSE
2 GTEx Adipose Subcutaneous RP11-282O18.3 0.15 0.14 lasso 7 0.15 2.0e-12 5.9 -6.0 1.6e-09 -0.94 0.28 0.72 FALSE
3 GTEx Adipose Visceral Omentum MPHOSPH9 0.07 0.02 lasso 4 0.00 3.5e-01 5.9 6.1 8.0e-10 0.91 0.05 0.67 FALSE
4 GTEx Adipose Visceral Omentum CDK2AP1 0.14 0.14 lasso 4 0.11 2.7e-06 5.9 -5.7 1.5e-08 -0.87 0.18 0.82 FALSE
5 GTEx Adipose Visceral Omentum RP11-282O18.3 0.14 0.11 enet 12 0.10 6.7e-06 5.9 -6.1 1.1e-09 -0.93 0.15 0.84 FALSE
6 GTEx Artery Aorta MPHOSPH9 0.08 0.01 lasso 4 0.04 4.6e-03 -2.4 5.3 1.2e-07 0.79 0.07 0.80 FALSE
7 GTEx Artery Aorta CDK2AP1 0.17 0.19 lasso 2 0.15 8.0e-09 6.0 -6.0 1.9e-09 -0.94 0.13 0.87 FALSE
8 GTEx Artery Aorta C12orf65 0.11 0.07 lasso 10 0.08 5.8e-05 6.2 -5.6 2.1e-08 -0.84 0.05 0.94 FALSE
9 GTEx Artery Aorta RP11-282O18.3 0.18 0.19 lasso 9 0.16 4.3e-09 6.0 -6.1 9.6e-10 -0.97 0.12 0.88 FALSE
10 GTEx Artery Tibial MPHOSPH9 0.05 0.03 lasso 3 0.03 2.2e-03 6.2 6.5 1.1e-10 0.94 0.07 0.89 FALSE
11 GTEx Artery Tibial ABCB9 0.04 0.02 lasso 2 0.01 3.0e-02 4.6 5.7 1.0e-08 0.92 0.08 0.86 FALSE
12 GTEx Artery Tibial SETD8 0.07 0.03 lasso 7 0.03 2.2e-03 5.9 5.4 7.2e-08 0.91 0.07 0.88 FALSE
13 GTEx Breast Mammary Tissue CDK2AP1 0.08 0.06 lasso 3 0.07 1.2e-04 5.9 -6.2 4.2e-10 -0.97 0.05 0.92 FALSE
14 GTEx Breast Mammary Tissue RP11-282O18.3 0.10 0.06 lasso 6 0.08 5.4e-05 5.9 -6.5 8.3e-11 -0.97 0.04 0.95 FALSE
15 GTEx Breast Mammary Tissue (Female) CDK2AP1 0.08 0.03 lasso 3 0.02 6.4e-02 6.0 -6.3 3.7e-10 -0.97 0.04 0.71 FALSE
16 GTEx Breast Mammary Tissue (Female) RP11-282O18.3 0.09 0.07 enet 8 0.08 2.8e-03 6.5 -6.4 1.4e-10 -0.98 0.04 0.90 FALSE
17 GTEx Cells Transformed fibroblasts OGFOD2 0.10 0.07 lasso 7 0.07 3.1e-06 5.2 5.9 3.6e-09 0.93 0.27 0.73 FALSE
18 GTEx Cells Transformed fibroblasts CDK2AP1 0.31 0.32 lasso 8 0.35 8.5e-27 6.0 -6.1 1.3e-09 -0.95 0.25 0.75 FALSE
19 GTEx Cells Transformed fibroblasts C12orf65 0.07 0.05 lasso 4 0.04 5.8e-04 5.7 -6.6 3.6e-11 -0.93 0.12 0.81 FALSE
20 GTEx Cells Transformed fibroblasts ABCB9 0.08 0.12 enet 7 0.12 4.3e-09 4.9 5.8 6.7e-09 0.87 0.22 0.78 FALSE
21 GTEx Cells Transformed fibroblasts RP11-282O18.3 0.25 0.29 enet 16 0.28 2.2e-21 6.0 -6.2 6.3e-10 -0.95 0.25 0.75 FALSE
22 GTEx Colon Sigmoid ABCB9 0.18 0.16 lasso 6 0.15 4.8e-06 6.1 5.8 5.9e-09 0.93 0.12 0.85 FALSE
23 GTEx Colon Transverse CDK2AP1 0.17 0.19 enet 7 0.22 1.4e-10 6.0 -6.1 9.4e-10 -0.96 0.21 0.79 FALSE
24 GTEx Colon Transverse ABCB9 0.08 0.07 enet 5 0.09 5.3e-05 5.9 5.7 1.2e-08 0.89 0.21 0.70 FALSE
25 GTEx Colon Transverse RP11-282O18.3 0.18 0.19 enet 8 0.19 1.8e-09 6.0 -6.1 7.8e-10 -0.97 0.19 0.81 FALSE
26 GTEx Esophagus Gastroesophageal Junction RP11-282O18.3 0.16 0.06 lasso 9 0.07 2.3e-03 6.2 -5.8 7.0e-09 -0.86 0.09 0.53 FALSE
27 GTEx Esophagus Mucosa CDK2AP1 0.30 0.36 lasso 5 0.38 1.9e-26 6.1 -6.2 5.1e-10 -0.97 0.17 0.83 FALSE
28 GTEx Esophagus Mucosa ABCB9 0.10 0.03 lasso 5 0.05 5.4e-04 5.9 6.0 1.9e-09 0.89 0.09 0.89 FALSE
29 GTEx Esophagus Mucosa RP11-282O18.3 0.29 0.34 lasso 4 0.34 1.9e-23 6.2 -6.2 6.8e-10 -0.95 0.14 0.86 FALSE
30 GTEx Esophagus Muscularis MPHOSPH9 0.18 0.18 enet 17 0.18 4.8e-11 6.0 6.6 5.1e-11 0.90 0.09 0.91 FALSE
31 GTEx Esophagus Muscularis C12orf65 0.06 0.04 lasso 4 0.04 2.0e-03 5.8 -6.1 1.4e-09 -0.92 0.18 0.74 FALSE
32 GTEx Esophagus Muscularis ABCB9 0.10 0.08 lasso 6 0.05 3.8e-04 6.2 6.0 1.6e-09 0.94 0.11 0.86 FALSE
33 GTEx Esophagus Muscularis RP11-282O18.3 0.19 0.11 lasso 6 0.10 2.1e-06 6.1 -6.0 2.1e-09 -0.94 0.16 0.84 FALSE
34 GTEx Heart Left Ventricle MPHOSPH9 0.06 0.04 lasso 5 0.04 4.2e-03 6.3 5.6 2.7e-08 0.87 0.05 0.86 FALSE
35 GTEx Heart Left Ventricle ABCB9 0.10 0.14 lasso 5 0.10 4.2e-06 5.9 5.9 4.6e-09 0.83 0.19 0.79 FALSE
36 GTEx Lung CDK2AP1 0.08 0.03 lasso 4 0.00 2.0e-01 6.0 -5.6 1.9e-08 -0.92 0.11 0.82 FALSE
37 GTEx Lung ABCB9 0.04 0.02 lasso 3 0.02 8.0e-03 6.3 6.3 3.8e-10 0.95 0.08 0.81 FALSE
38 GTEx Lung RP11-282O18.3 0.06 0.02 lasso 7 0.00 6.1e-01 6.0 -5.9 4.6e-09 -0.94 0.11 0.75 FALSE
39 GTEx Muscle Skeletal SETD8 0.16 0.02 lasso 4 0.03 3.8e-04 5.8 6.1 1.0e-09 0.87 0.25 0.69 FALSE
40 GTEx Nerve Tibial MPHOSPH9 0.07 0.04 lasso 4 0.01 7.0e-02 6.1 5.9 4.5e-09 0.94 0.14 0.67 FALSE
41 GTEx Nerve Tibial CDK2AP1 0.11 0.11 enet 25 0.09 4.4e-07 5.9 -5.8 5.2e-09 -0.93 0.17 0.83 FALSE
42 GTEx Nerve Tibial C12orf65 0.05 0.07 lasso 3 0.06 3.0e-05 6.2 -6.5 8.0e-11 -0.90 0.05 0.91 FALSE
43 GTEx Nerve Tibial ABCB9 0.06 0.04 lasso 3 0.05 3.5e-04 5.9 6.2 6.3e-10 0.95 0.13 0.84 FALSE
44 GTEx Nerve Tibial RP11-282O18.3 0.10 0.10 enet 28 0.08 1.9e-06 5.9 -5.3 1.3e-07 -0.86 0.18 0.82 FALSE
45 GTEx Pancreas CDK2AP1 0.24 0.27 lasso 3 0.26 3.1e-11 6.0 -6.1 1.3e-09 -0.97 0.24 0.76 FALSE
46 GTEx Pancreas ARL6IP4 0.07 0.07 lasso 2 0.07 9.6e-04 5.9 -6.2 7.5e-10 -0.91 0.06 0.79 FALSE
47 GTEx Pancreas SETD8 0.20 0.12 lasso 5 0.13 3.4e-06 5.9 -5.7 1.2e-08 -0.93 0.44 0.55 FALSE
48 GTEx Pancreas RP11-282O18.3 0.22 0.24 lasso 5 0.24 2.3e-10 6.0 -6.1 1.3e-09 -0.96 0.24 0.76 FALSE
49 GTEx Skin Not Sun Exposed Suprapubic CDK2AP1 0.17 0.12 lasso 10 0.12 3.4e-07 6.1 -6.4 1.2e-10 -0.96 0.06 0.94 FALSE
50 GTEx Skin Not Sun Exposed Suprapubic ABCB9 0.13 0.15 lasso 11 0.11 2.1e-06 4.9 5.3 1.2e-07 0.84 0.42 0.57 FALSE
51 GTEx Skin Not Sun Exposed Suprapubic RP11-282O18.3 0.13 0.10 lasso 6 0.09 1.9e-05 6.3 -6.4 1.4e-10 -0.96 0.06 0.94 FALSE
52 GTEx Skin Sun Exposed Lower leg MPHOSPH9 0.06 0.05 enet 9 0.06 2.1e-05 6.0 5.6 1.7e-08 0.90 0.09 0.88 FALSE
53 GTEx Skin Sun Exposed Lower leg CDK2AP1 0.21 0.22 lasso 5 0.22 3.4e-18 6.0 -6.2 5.0e-10 -0.94 0.16 0.84 FALSE
54 GTEx Skin Sun Exposed Lower leg ABCB9 0.09 0.08 lasso 5 0.08 4.3e-07 4.9 5.2 1.6e-07 0.82 0.27 0.73 FALSE
55 GTEx Skin Sun Exposed Lower leg RP11-282O18.3 0.17 0.20 lasso 6 0.20 2.2e-16 6.0 -6.1 1.3e-09 -0.93 0.16 0.84 FALSE
56 GTEx Small Intestine Terminal Ileum ABCB9 0.23 0.21 enet 12 0.22 1.0e-05 6.3 5.5 5.0e-08 0.89 0.09 0.71 FALSE
57 GTEx Stomach MPHOSPH9 0.17 0.08 lasso 5 0.10 1.2e-05 6.2 6.2 4.2e-10 0.95 0.07 0.92 FALSE
58 GTEx Testis MPHOSPH9 0.28 0.27 enet 23 0.32 1.3e-14 6.3 6.4 1.6e-10 0.97 0.04 0.96 FALSE
59 GTEx Testis CDK2AP1 0.20 0.14 lasso 5 0.13 2.0e-06 6.0 -5.9 4.7e-09 -0.83 0.14 0.84 FALSE
60 GTEx Thyroid MPHOSPH9 0.10 0.08 enet 20 0.09 2.0e-07 6.5 5.8 8.4e-09 0.94 0.04 0.96 FALSE
61 GTEx Thyroid PITPNM2 0.04 0.07 lasso 2 0.06 1.6e-05 6.1 6.1 1.1e-09 0.96 0.08 0.90 FALSE
62 GTEx Thyroid CDK2AP1 0.08 0.09 enet 7 0.10 8.2e-08 6.0 -6.2 5.3e-10 -0.96 0.17 0.83 FALSE
63 GTEx Thyroid RP11-282O18.3 0.06 0.06 enet 6 0.06 3.6e-05 6.0 -6.1 8.3e-10 -0.95 0.17 0.82 FALSE
64 METSIM Adipose CDK2AP1 0.11 0.14 enet 23 0.14 1.7e-20 6.4 -6.4 1.6e-10 -0.94 0.06 0.94 FALSE
65 METSIM Adipose MPHOSPH9 0.03 0.01 bslmm 348 0.01 1.2e-02 6.3 5.7 1.4e-08 0.77 0.04 0.86 FALSE
66 YFS Blood MPHOSPH9 0.05 0.07 enet 31 0.07 3.7e-23 6.1 5.7 1.5e-08 0.96 0.03 0.97 FALSE
67 YFS Blood SBNO1 0.03 0.03 lasso 6 0.03 1.2e-09 6.2 -5.5 4.5e-08 -0.94 0.06 0.94 FALSE
68 The Cancer Genome Atlas Bladder Urothelial Carcinoma ABCB9 0.05 0.04 enet 5 0.04 2.4e-04 6.3 5.3 9.1e-08 0.91 0.00 0.97 FALSE
69 The Cancer Genome Atlas Bladder Urothelial Carcinoma CDK2AP1 0.09 0.08 lasso 2 0.06 5.9e-06 6.2 -6.2 6.3e-10 -0.93 0.02 0.98 FALSE
70 The Cancer Genome Atlas Breast Invasive Carcinoma CDK2AP1 0.07 0.08 lasso 7 0.08 5.0e-16 6.2 -6.4 1.7e-10 -0.98 0.01 0.99 FALSE
71 The Cancer Genome Atlas Breast Invasive Carcinoma RILPL2 0.02 0.01 enet 8 0.01 2.6e-02 5.9 5.3 1.3e-07 0.87 0.01 0.97 FALSE
72 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma CDK2AP1 0.07 0.07 blup 34 0.05 1.1e-03 6.4 -6.6 5.7e-11 -0.97 0.01 0.91 FALSE
73 The Cancer Genome Atlas Colon Adenocarcinoma CDK2AP1 0.12 0.17 lasso 4 0.17 6.3e-10 6.2 -6.3 4.0e-10 -0.94 0.01 0.99 FALSE
74 The Cancer Genome Atlas Colon Adenocarcinoma RILPL2 0.09 0.09 blup 43 0.08 3.1e-05 5.9 5.5 3.3e-08 0.85 0.01 0.99 FALSE
75 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ABCB9 0.03 0.02 enet 9 0.03 3.4e-04 6.3 6.0 2.2e-09 0.77 0.00 0.91 FALSE
76 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CDK2AP1 0.14 0.15 lasso 2 0.14 7.8e-16 6.2 -6.2 4.6e-10 -0.93 0.04 0.96 FALSE
77 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CDK2AP1 0.11 0.13 lasso 5 0.14 5.9e-16 6.0 -6.2 5.0e-10 -0.98 0.01 0.99 FALSE
78 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma C12orf65 0.05 0.04 blup 34 0.05 1.0e-03 4.4 -5.3 1.3e-07 -0.82 0.04 0.64 FALSE
79 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma CDK2AP1 0.12 0.10 lasso 2 0.11 6.3e-07 6.2 -6.2 4.3e-10 -0.93 0.03 0.97 FALSE
80 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PITPNM2 0.06 0.07 lasso 5 0.09 1.2e-05 6.5 -6.6 4.2e-11 -0.96 0.02 0.98 FALSE
81 The Cancer Genome Atlas Liver Hepatocellular Carcinoma CDK2AP1 0.11 0.11 enet 5 0.11 1.2e-05 6.0 -6.2 6.3e-10 -0.95 0.01 0.98 FALSE
82 The Cancer Genome Atlas Lung Adenocarcinoma CDK2AP1 0.03 0.04 lasso 1 0.04 1.2e-05 6.2 -6.2 6.3e-10 -0.93 0.02 0.98 FALSE
83 The Cancer Genome Atlas Lung Squamous Cell Carcinoma ABCB9 0.06 0.06 enet 7 0.07 5.2e-08 5.2 5.6 2.4e-08 0.85 0.06 0.94 FALSE
84 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CDK2AP1 0.04 0.04 lasso 3 0.03 3.8e-04 6.0 -5.9 2.8e-09 -0.94 0.02 0.95 FALSE
85 The Cancer Genome Atlas Lung Squamous Cell Carcinoma OGFOD2 0.02 0.04 lasso 3 0.03 1.3e-04 5.1 5.2 2.2e-07 0.78 0.01 0.92 FALSE
86 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma CDK2AP1 0.07 0.06 enet 7 0.06 7.0e-05 6.0 -6.1 9.9e-10 -0.89 0.01 0.93 FALSE
87 The Cancer Genome Atlas Pancreatic Adenocarcinoma CDK2AP1 0.12 0.14 blup 34 0.15 7.2e-07 5.9 -6.8 1.4e-11 -0.94 0.01 0.98 TRUE
88 The Cancer Genome Atlas Prostate Adenocarcinoma ABCB9 0.04 0.05 enet 10 0.05 1.2e-05 5.1 5.2 1.8e-07 0.75 0.11 0.88 FALSE
89 The Cancer Genome Atlas Prostate Adenocarcinoma ARL6IP4 0.03 0.04 blup 17 0.04 1.6e-05 5.2 -5.5 5.0e-08 -0.83 0.04 0.94 FALSE
90 The Cancer Genome Atlas Prostate Adenocarcinoma CDK2AP1 0.06 0.07 lasso 2 0.06 1.7e-06 6.0 -6.0 2.4e-09 -0.94 0.02 0.98 FALSE
91 The Cancer Genome Atlas Stomach Adenocarcinoma CDK2AP1 0.09 0.10 lasso 2 0.10 1.8e-07 6.0 -6.2 6.2e-10 -0.94 0.01 0.99 FALSE
92 The Cancer Genome Atlas Testicular Germ Cell Tumors CDK2AP1 0.13 0.10 blup 34 0.11 8.2e-05 6.0 -6.3 3.6e-10 -0.93 0.01 0.97 FALSE
93 The Cancer Genome Atlas Thyroid Carcinoma CDK2AP1 0.08 0.10 lasso 2 0.10 1.3e-09 6.0 -6.1 1.3e-09 -0.94 0.04 0.96 FALSE
94 The Cancer Genome Atlas Thyroid Carcinoma MPHOSPH9 0.27 0.09 lasso 4 0.09 9.8e-09 5.7 5.9 3.8e-09 0.83 0.08 0.92 FALSE
95 The Cancer Genome Atlas Thyroid Carcinoma OGFOD2 0.02 0.00 enet 4 0.02 2.7e-03 5.2 5.5 4.7e-08 0.71 0.01 0.50 FALSE
96 The Cancer Genome Atlas Thyroid Carcinoma SBNO1 0.03 0.01 blup 59 0.02 9.4e-03 6.4 -5.4 5.8e-08 -0.73 0.01 0.72 FALSE