Hub : Genes

SETD8

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0370	0.0180	2.9e-04	0.014	0.018	0.014	0.015	0.014	7.1e-03	2.8e-03	6.8e-03	5.4e-03	6.4e-03
2	GTEx	Artery Tibial	0.0747	0.0348	6.7e-04	0.028	NA	0.029	NA	0.029	2.6e-03	NA	2.3e-03	NA	2.2e-03
3	GTEx	Brain Cerebellum	0.1270	0.0570	3.3e-03	0.159	NA	0.083	NA	0.110	2.0e-05	NA	1.9e-03	NA	4.0e-04
4	GTEx	Cells Transformed fibroblasts	0.1020	0.0400	4.2e-06	0.122	NA	0.095	NA	0.091	2.0e-09	NA	1.4e-07	NA	2.4e-07
5	GTEx	Muscle Skeletal	0.1617	0.0623	3.8e-05	0.025	NA	0.023	NA	0.032	1.6e-03	NA	2.4e-03	NA	3.8e-04
6	GTEx	Nerve Tibial	0.0753	0.0413	7.0e-03	0.007	NA	0.012	NA	0.008	9.6e-02	NA	4.2e-02	NA	8.1e-02
7	GTEx	Pancreas	0.2040	0.0760	3.0e-05	0.121	NA	0.114	NA	0.132	8.6e-06	NA	1.6e-05	NA	3.4e-06
8	YFS	Blood	0.0950	0.0289	8.9e-15	0.046	0.052	0.066	0.063	0.068	1.1e-14	1.8e-16	1.4e-20	8.0e-20	2.9e-21

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	3.4	5.4	9.2	-2.3	2.3	-2.0	3.0	3.0	-1.0	-2.8	1.1
Bipolar Disorder or Schizophrenia	8.5	20.8	31.4	-4.7	4.1	-4.5	5.6	5.6	-3.3	-5.2	2.7
Depressed Affect (Nagel 2018)	1.7	3.6	9.4	2.0	-3.1	0.1	-1.8	-1.8	-1.4	2.3	1.4
Depression (Nagel 2018)	0.8	1.1	2.9	1.0	-1.7	-0.3	-0.1	-0.2	-1.6	1.0	1.3
Intelligence (Savage-Jansen 2018)	6.5	19.9	27.9	-4.9	5.0	-4.9	4.9	5.3	-2.0	-5.1	2.1
Neuroticism (Nagel 2018)	1.1	2.5	7.5	1.4	-2.7	-0.5	-1.4	-1.2	-1.6	1.7	1.1
Schizophrenia (2018)	8.0	16.7	23.4	-4.1	3.2	-4.1	4.8	4.7	-4.0	-4.3	3.1
Schizophrenia vs Biploar Disorder	1.6	2.2	3.8	-1.5	1.7	-1.1	1.9	1.5	-1.1	-2.0	-0.5
Worry (Nagel 2018)	0.3	0.7	2.0	0.8	-1.4	-0.7	-0.8	-0.4	-1.0	0.6	0.2
Alzheimer’s Disease (in mother)	1.0	1.2	2.8	-1.1	0.9	-1.0	0.9	1.4	-0.5	-0.8	1.7
Alzheimer’s Disease (in father)	0.2	0.2	0.8	-0.0	-0.2	0.5	-0.1	0.8	0.0	0.1	-0.9
Alzheimer’s Disease (including proxy)	0.1	0.2	0.5	0.4	-0.3	0.3	-0.2	0.7	0.5	0.4	0.0
Crohns Disease (2017)	1.2	2.7	4.8	-1.9	2.2	-1.1	2.2	1.6	-0.6	-2.1	-0.5
Irritable Bowel Disease (IBD)	0.6	1.3	2.7	-1.6	1.3	-0.8	1.4	0.6	-1.1	-1.4	-0.3
Ulcerative Colitis (UC)	0.1	0.2	1.3	-0.7	-0.2	-0.1	0.0	-0.5	-1.1	0.0	0.2
Major Depression (MDD)	2.6	3.1	7.0	1.7	-2.6	1.5	-1.8	-1.9	0.3	2.4	0.2
Reaction Time	1.7	3.3	9.4	1.5	-3.1	0.8	-2.1	-0.9	-1.0	2.3	1.6
Verbal and Numeric Reasoning (VNR)	5.2	12.5	17.5	-3.9	3.9	-4.0	3.8	4.2	-1.2	-4.2	1.9
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ovarian Cancer	2.6	3.4	6.5	1.7	-2.5	1.0	-1.9	-2.5	-1.1	2.2	0.9
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	1.9	2.8	5.8	-1.4	2.4	-1.0	2.1	1.8	0.6	-2.3	-0.8
Bipolar Disorder (2011)	1.1	1.0	2.6	-0.7	0.4	-1.6	0.9	0.6	-1.6	-0.8	0.9
Body Mass Index (BMI) (2010)	3.7	5.0	8.4	-2.0	1.9	-2.5	2.3	2.9	-2.5	-2.0	1.4
Coronary Artery Disease (CAD)	0.6	0.7	2.5	-1.6	1.4	-0.4	0.5	-0.1	0.6	-0.7	-0.2
Crohns Disease (2012)	0.9	1.5	2.6	-1.5	1.6	-0.7	1.6	1.1	0.0	-1.5	-0.4
Mean Putamen Volume	0.6	0.7	1.8	-1.0	1.3	0.2	0.6	1.2	-0.2	-0.6	-0.7
Fasting Glucose	1.2	1.4	5.2	-1.3	-0.2	-1.6	0.3	-0.2	-2.3	-0.4	1.3
HbA1C	0.8	0.9	4.6	0.8	0.0	1.0	-0.9	0.2	0.2	0.2	-2.1
HDL Cholesterol	4.3	7.1	25.3	-0.8	-0.9	-2.6	1.3	2.2	-5.0	-0.4	4.1
LDL Cholesterol	1.0	1.5	4.7	-0.8	0.2	-1.9	0.9	-0.7	-1.3	-0.2	2.2
Lupus	0.5	0.7	3.2	-0.3	-0.8	-0.1	0.0	-0.8	-1.8	0.5	0.9
Neuroticism (2016)	1.1	1.6	7.7	-0.7	-0.7	-1.6	0.6	-0.2	-1.2	0.1	2.8
Primary Biliary Cirrhosis	4.2	6.0	15.2	-3.9	1.9	-2.6	2.6	2.1	-2.0	-2.6	0.4
Rheumatoid Arthritis	0.6	0.8	1.8	-0.1	-1.0	-0.3	-1.2	-0.9	0.3	1.0	-1.4
Schizophrenia (2014)	9.3	20.6	31.2	-4.9	4.0	-3.7	5.6	5.6	-4.2	-5.0	2.5
Triglycerides	0.9	1.4	6.2	0.2	-0.4	0.7	-0.7	-2.5	1.6	0.9	-0.7
Type 2 Diabetes (T2D) (2012)	7.7	8.9	13.9	2.5	-3.0	3.0	-3.1	-3.7	2.7	3.2	-2.3
Ulcerative Colitis	0.4	0.5	1.4	-0.2	-0.0	0.5	-0.4	-1.1	0.9	0.3	-1.2
Blood Eosinophil Count	4.1	31.5	71.9	4.0	-8.0	0.5	-5.3	-8.5	-3.2	6.8	3.9
Blood Platelet Count	7.3	84.2	169.0	8.6	-12.7	4.2	-9.9	-13.0	0.5	12.0	3.2
Blood Red Count	1.8	17.9	25.9	4.3	-2.6	4.8	-5.0	-5.1	4.0	3.5	-4.1
Blood White Count	1.0	7.3	22.2	-1.9	-0.8	-2.1	1.2	-2.7	-4.7	0.4	4.3
Heel T-Score	8.0	63.3	104.0	8.8	-10.0	7.4	-10.0	-7.9	2.7	10.2	-1.2
BMI	0.3	1.8	5.1	2.2	-1.4	1.8	-1.1	0.1	-0.5	1.2	-0.9
Height	9.2	177.9	329.1	-13.5	18.1	-9.6	16.5	15.0	-3.6	-17.6	-1.7
Waist Hip Ratio (WHR)	10.1	45.3	171.6	4.4	-6.8	3.6	-6.2	-13.1	4.2	7.5	-0.9
Systolic Blood Pressure	1.2	5.9	8.1	2.1	-1.9	2.3	-2.8	-2.8	2.6	2.3	-2.5
Smoking Status	0.3	0.6	1.7	0.3	-0.5	0.8	-0.4	-1.3	1.1	0.8	0.6
Allergy or Eczema	5.9	15.4	26.8	4.0	-5.0	3.6	-4.7	-4.2	1.7	5.2	-0.0
Cardiovascular Disease	0.8	2.8	7.6	0.6	-2.3	-1.7	-0.6	-1.3	-1.8	1.0	2.8
Hypothyroidism (self reported)	4.4	10.0	16.4	-2.6	2.8	-4.0	3.2	3.6	-2.2	-3.5	3.1
Respiratory disease	3.5	7.7	17.5	2.3	-3.5	2.2	-3.1	-4.2	0.6	3.5	-0.0
Type 2 Diabetes (T2D) (2018)	2.8	5.2	14.1	1.8	-3.0	0.8	-2.3	-3.8	-0.6	2.8	1.2
Lung FEV1/FVC ratio	1.2	6.2	10.7	1.1	-2.6	2.6	-2.7	-3.3	2.1	2.9	-1.9
Lung FVC	5.3	27.2	46.6	4.5	-4.3	6.8	-6.7	-3.7	3.1	5.4	-5.8
Neuroticism	0.9	2.2	5.3	1.1	-2.3	-1.1	-0.7	-0.9	-1.9	1.3	1.9
Chronotype (morning person)	0.7	1.7	3.0	-0.4	1.7	-1.2	1.6	1.2	-1.3	-1.7	0.1
Hair Pigment	0.9	25.4	42.9	5.4	-6.2	4.0	-6.0	-6.3	0.8	6.5	-0.4
Tanning	0.1	1.7	3.3	-1.6	1.8	0.4	1.1	1.2	0.1	-1.5	-1.6
Hand grip strength (left)	1.9	5.0	22.5	0.3	1.7	2.7	-0.7	-1.1	2.4	-0.2	-4.7
Number of treatments/medications taken	1.0	1.7	5.5	0.7	-2.3	-0.7	-0.6	-1.3	-0.6	1.2	1.8
Average weekly spirits intake	1.5	1.9	3.9	2.0	-1.6	1.1	-1.3	-1.5	0.9	1.6	-0.1
Sensitivity / hurt feelings	0.2	0.4	1.5	0.2	-0.9	0.2	-0.5	-1.2	-0.2	0.6	0.2
Frequency of depressed mood in last 2 weeks	1.2	1.7	4.4	0.5	-1.4	-1.0	-0.2	-0.9	-2.1	0.7	2.1
Hearing difficulty/problems: Yes	0.1	0.2	0.5	0.4	-0.1	0.3	0.1	-0.6	0.7	0.2	-0.3
Relative age of first facial hair	1.5	3.1	5.6	1.8	-2.4	1.4	-2.2	-1.3	1.3	2.1	-0.9
Other serious medical condition/disability diagnosed by doctor	3.4	4.4	10.1	-1.4	0.7	-2.3	2.3	1.7	-2.5	-1.5	3.2
Ever used hormone-replacement therapy (HRT)	1.0	1.3	4.1	-0.1	1.2	0.9	0.0	0.1	2.0	-0.7	-2.0
Ever had hysterectomy (womb removed)	3.8	4.3	6.7	1.9	-2.4	1.9	-2.5	-2.5	1.4	2.6	-0.2
Systolic blood pressure, automated reading	2.0	5.7	7.6	2.3	-1.8	2.7	-2.7	-2.8	2.0	2.5	-2.2
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	2.2	1.4	-0.6	0.5	-0.8	-1.5	1.4	0.8	0.1
Angina	1.8	2.3	6.7	-0.9	0.6	-2.2	1.5	0.9	-1.4	-1.0	2.6
Medication for hormone replacement therapy	0.2	0.2	0.7	-0.3	-0.1	0.6	-0.4	-0.6	0.8	0.1	-0.1
Vitamin and mineral supplements	1.4	1.9	5.6	-2.4	1.8	-1.4	1.2	0.7	-0.8	-1.4	0.0
Supplements: Zinc	1.2	1.3	2.8	0.0	-0.0	-1.6	1.7	1.3	-0.8	-0.9	1.4
Medication: Co-codamol	1.0	1.2	3.1	1.6	-1.8	0.1	-0.7	-0.8	-0.5	1.1	1.2
Medication: Metformin	2.0	2.9	7.6	1.2	-2.5	0.7	-1.7	-2.8	0.0	2.1	0.6
Diabetes (father)	2.4	3.0	5.3	1.8	-2.1	1.9	-2.3	-1.6	0.1	2.0	-0.8
Diabetes (mother)	0.3	0.4	1.4	0.5	-1.2	0.1	-0.5	-0.4	-0.6	0.9	0.4
Severe depression (siblings)	1.3	1.5	3.1	-0.7	0.8	-1.3	1.5	1.8	-1.3	-1.3	0.5
Pack years adult smoking proportion	0.4	0.6	1.6	1.3	-0.7	-0.2	-0.7	-0.7	-0.1	0.7	1.1
Impedance of leg (right)	1.2	5.6	11.9	2.1	-3.4	1.1	-2.7	-2.8	1.6	3.0	0.7
Leg fat-free mass (left)	4.5	23.9	47.7	-4.0	6.9	-3.1	5.7	6.2	-2.1	-6.5	-1.1
Trunk fat percentage	0.4	1.5	4.8	2.0	-1.2	0.2	-0.6	2.2	-0.8	0.5	0.2
Hand grip strength (right)	1.2	3.2	12.1	-0.4	2.2	1.8	-0.2	-0.9	1.9	-0.7	-3.5
Townsend deprivation index at recruitment	0.4	0.6	1.3	0.8	-0.9	-0.2	-0.7	-0.7	0.1	0.8	1.1
Current tobacco smoking	1.2	1.9	4.9	0.9	-0.9	0.9	-1.3	-2.2	1.3	1.8	1.2
Average weekly fortified wine intake	0.1	0.1	0.6	0.1	0.1	-0.0	0.2	0.8	0.1	-0.3	-0.6
Maternal smoking around birth	1.7	2.5	4.5	0.6	-1.3	2.1	-1.6	-2.1	1.2	1.8	-1.1
Fed-up feelings	3.2	5.8	11.1	2.8	-3.3	1.4	-2.8	-2.7	-0.6	3.2	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.8	4.2	1.2	-2.1	-0.3	-0.4	-1.6	-1.3	1.4	1.4
Relative age voice broke	2.6	3.9	5.4	2.2	-1.9	2.2	-2.3	-1.5	1.7	2.0	-1.8
Taking other prescription medications	0.9	1.4	3.3	0.6	-1.8	-0.1	-0.7	-1.7	-1.2	1.1	1.3
Age when periods started (menarche)	0.4	0.8	2.0	-0.3	-1.4	-0.2	-0.9	-0.7	-1.2	1.0	0.9
Bilateral oophorectomy (both ovaries removed)	3.6	4.2	8.9	1.8	-2.3	1.9	-2.4	-3.0	0.7	2.5	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	3.1	7.0	15.6	2.4	-3.9	1.8	-3.1	-2.5	0.8	3.6	1.1
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	1.9	-1.0	0.8	-0.9	1.0	0.7	-0.7	-0.6	1.4
Qualifications: CSEs or equivalent	2.0	2.7	5.2	1.4	-1.6	1.7	-2.3	-1.8	0.4	2.0	-1.1
Serious illness, injury or assault to yourself	1.0	1.2	2.5	-1.6	1.6	-0.3	1.1	1.1	0.0	-1.3	-0.5
High blood pressure	0.7	2.0	3.6	1.4	-1.9	-0.1	-1.3	-1.8	0.2	1.7	1.5
Hayfever, allergic rhinitis or eczema	6.0	12.9	20.9	3.5	-4.2	3.6	-4.4	-3.8	2.1	4.6	-1.3
Multivitamins +/- minerals	1.3	1.7	3.3	1.7	-1.4	1.8	-0.8	-0.7	1.6	1.3	-0.1
Stomach or abdominal pain in last month	0.6	0.7	1.9	0.8	-1.4	-0.1	-0.5	-0.2	0.4	1.0	1.4
Supplements: Glucosamine	4.0	5.2	6.8	2.6	-2.5	2.0	-2.6	-2.2	2.2	2.3	-1.5
Diverticular disease/diverticulitis (self-reported)	1.8	2.1	4.2	1.4	-1.8	1.0	-1.5	-1.6	1.4	2.0	0.2
Medication: Atenolol	0.4	0.4	0.8	-0.4	0.4	-0.7	0.7	0.8	-0.9	-0.7	0.6
Medication: Levothyroxine sodium	5.1	8.7	14.4	-3.1	2.6	-3.8	3.4	2.2	-1.9	-3.0	3.3
Sitting height	16.3	115.8	193.2	-11.3	13.9	-8.1	13.2	12.6	-3.7	-13.9	-0.3
Chronic bronchitis/emphysema (father)	0.7	0.8	2.5	-0.2	-1.2	0.1	-1.0	-1.6	-0.0	1.1	0.3
High blood pressure (mother)	0.1	0.1	0.3	0.1	-0.5	-0.5	0.4	0.2	-0.1	0.1	0.5
Body mass index (BMI)	0.3	1.2	4.1	2.0	-1.0	1.2	-1.1	-0.2	-0.1	1.2	-0.6
Impedance of leg (left)	1.9	9.3	20.4	2.7	-4.5	1.6	-3.6	-3.6	1.6	4.0	0.6
Leg predicted mass (left)	4.5	23.7	47.2	-4.0	6.9	-3.1	5.7	6.1	-2.1	-6.5	-1.1
Trunk fat mass	0.5	2.2	11.0	0.4	1.1	-0.7	1.3	3.3	-1.1	-1.5	-0.2
Waist circumference	0.2	0.7	2.7	1.4	-0.5	0.4	-0.3	-1.6	-0.0	0.7	-0.3
Number of incorrect matches in round	1.1	1.8	5.0	1.3	-1.1	2.2	-0.9	-0.9	1.4	1.3	-1.1
Past tobacco smoking	1.4	2.6	6.0	2.4	-2.0	0.6	-2.1	-1.4	-0.3	2.1	0.4
Alcohol usually taken with meals	2.7	4.3	8.1	-2.6	2.6	-1.8	2.6	1.9	0.1	-2.8	-0.0
Nervous feelings	1.0	1.9	4.3	-0.9	-0.2	-2.1	1.0	1.1	-2.0	-0.7	1.7
Frequency of tenseness / restlessness in last 2 weeks	2.0	3.1	7.3	1.3	-2.7	-1.0	-1.1	-1.7	-1.7	1.6	2.3
Hearing difficulty/problems with background noise	3.5	5.5	11.4	-2.7	2.3	-2.6	3.4	1.9	-0.7	-2.8	1.4
Hair/balding pattern: Pattern 2	0.6	0.8	1.1	0.7	-0.7	1.0	-1.1	-1.0	0.6	1.1	0.6
Had menopause	6.8	8.5	15.5	-2.6	3.6	-2.1	3.7	3.6	-0.6	-3.9	-0.3
Had other major operations	2.4	2.9	9.3	-1.3	0.8	-2.2	1.9	0.7	-1.5	-1.0	3.0
Forced vital capacity (FVC)	0.9	3.4	18.5	-0.5	1.3	2.0	-0.8	1.2	0.9	-0.6	-4.3
Heel bone mineral density (BMD) T-score, automated (right)	2.7	6.1	14.1	1.9	-3.8	1.6	-3.1	-2.5	-0.1	3.5	1.0
Ever unenthusiastic/disinterested for a whole week	0.7	0.8	4.5	0.1	-1.0	0.1	-0.1	-0.3	-2.1	0.6	0.7
Qualifications: None of the above	11.5	24.7	45.3	5.4	-6.1	3.8	-5.5	-6.7	1.1	6.4	0.3
Financial difficulties in last 2 years	1.7	2.3	4.5	1.9	-1.0	1.2	-2.1	-1.1	2.0	1.7	-0.1
Mouth/teeth dental problems	0.6	0.9	3.9	0.4	-0.1	2.0	-0.9	0.1	0.7	0.5	-1.1
Heart attack	0.5	0.6	1.4	1.0	0.1	0.7	-0.3	-1.2	1.1	0.4	-0.5
Allergy	9.8	22.5	34.9	-4.7	5.3	-4.8	5.8	5.6	-2.4	-5.9	1.5
Pain all over the body in last month	0.7	0.7	3.4	1.9	-0.9	0.3	-0.4	-0.8	0.3	0.7	-0.0
Diabetes (self-reported)	1.2	1.9	6.5	0.7	-1.7	0.4	-1.1	-2.6	-0.0	1.7	0.8
Hayfever/allergic rhinitis (self-reported)	2.5	3.4	7.2	1.0	-2.5	1.7	-1.9	-2.3	0.4	2.7	0.8
Medication: Ramipril	0.3	0.4	1.2	0.3	-1.0	-0.3	-0.5	-1.1	-0.1	0.6	0.5
Medication: Simvastatin	0.9	1.4	4.3	-0.2	-1.2	-2.0	0.5	-0.5	-0.9	0.0	2.1
Fluid intelligence score	7.1	14.7	23.0	-4.3	4.0	-3.8	4.6	4.8	-1.4	-4.5	1.8
Illnesses of siblings	1.5	2.1	6.0	-1.9	0.8	-1.2	0.9	1.7	-2.5	-1.1	0.2
Neuroticism score	1.3	2.8	7.0	1.3	-2.6	-0.8	-1.2	-1.7	-1.8	1.6	1.7
Weight	2.4	11.7	21.9	-2.4	4.7	-2.0	4.2	4.6	-1.5	-4.5	-0.7
Impedance of arm (right)	0.3	1.4	6.9	0.4	-0.9	-1.1	0.1	2.6	-0.5	-0.2	1.3
Arm fat percentage (right)	0.5	1.8	6.4	2.5	-1.6	0.9	-1.4	1.0	-0.1	1.3	-0.1
Trunk fat-free mass	5.8	33.4	76.1	-5.8	8.7	-3.5	7.1	5.4	-1.3	-7.8	-1.7
Hip circumference	2.8	12.0	35.5	-1.9	4.2	-1.7	3.8	6.0	-2.0	-4.2	-0.7
Time employed in main current job	0.8	0.9	2.9	-0.8	0.1	-0.8	1.0	-0.5	-1.7	-0.2	1.4
Alcohol intake versus 10 years previously	4.7	7.0	10.9	3.1	-3.0	2.4	-3.3	-3.2	0.7	3.2	-0.7
Father’s age at death	4.1	5.5	11.6	-1.7	3.4	-0.7	2.5	3.2	1.2	-2.9	-1.5
Worrier / anxious feelings	0.8	1.5	4.0	2.0	-1.8	0.4	-1.3	-1.0	0.3	1.2	-0.4
Frequency of tiredness / lethargy in last 2 weeks	1.9	3.2	12.2	0.7	-1.4	-2.0	0.5	-0.4	-2.4	0.6	3.5
Falls in the last year	1.5	2.0	4.2	-1.0	1.0	-2.1	1.4	1.6	-0.9	-1.5	1.6
Hair/balding pattern: Pattern 3	0.1	0.2	0.4	0.4	0.1	0.6	-0.5	-0.3	0.7	0.5	-0.1
Number of live births	0.5	0.6	3.0	-0.6	0.4	-0.5	0.6	1.7	-0.6	-0.8	-0.1
Forced expiratory volume in 1-second (FEV1)	1.3	4.5	21.4	0.1	0.2	2.8	-1.8	0.2	1.7	0.5	-4.6
Pulse rate	0.1	0.1	0.3	0.5	0.1	0.5	0.4	0.1	-0.3	0.0	-0.6
Happiness	2.1	2.6	8.5	-1.1	0.3	-1.9	1.2	0.7	-2.9	-1.0	2.1
Noisy workplace	4.0	4.9	9.3	2.2	-2.5	2.1	-2.4	-3.0	-0.1	2.9	-0.3
Qualifications: A levels/AS levels or equivalent	16.3	36.1	54.8	-6.7	6.2	-6.2	7.1	7.4	-2.4	-7.0	2.9
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	3.3	-0.9	-0.2	-0.5	0.7	0.8	-1.3	-0.4	1.8
Mouth/teeth dental problems: Dentures	0.2	0.3	0.6	0.8	0.3	-0.7	0.5	-0.1	0.7	-0.3	0.8
Asthma	3.4	6.7	16.8	1.8	-3.4	1.9	-2.6	-4.1	-0.4	3.3	0.3
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	3.1	1.6	-1.8	0.1	-0.9	-0.5	0.4	1.0	-0.0
Medication: Cholesterol lowering	1.1	1.7	5.3	-1.0	-0.4	-2.0	1.1	0.1	-1.3	-0.3	2.3
Depression (self-reported)	2.4	2.9	5.5	1.7	-2.1	1.2	-1.6	-2.4	0.1	2.3	0.9
Medication: Lansoprazole	3.0	3.5	6.1	2.2	-2.5	1.4	-1.9	-2.3	0.6	2.3	0.6
Prospective memory result	1.4	1.7	3.0	1.6	-0.7	1.6	-1.3	-0.5	1.4	0.9	-1.7
Lung cancer (father)	0.4	0.5	1.5	0.2	0.2	-0.4	1.2	-0.1	-1.2	-0.4	0.9
Illnesses of mother	0.5	0.6	3.0	-0.1	-0.3	0.6	-0.8	-1.7	-0.6	0.7	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.6	18.5	0.0	0.4	2.4	-1.5	0.4	1.4	0.3	-4.3
Pulse wave Arterial Stiffness index	2.8	3.3	5.6	-2.4	1.9	-2.0	2.2	1.4	-1.5	-2.0	0.2
Impedance of arm (left)	0.3	1.6	7.0	0.4	-1.1	-1.3	-0.1	2.6	-0.7	-0.2	1.5
Arm fat mass (right)	0.2	1.0	4.5	0.6	0.9	-0.0	0.6	2.1	-0.6	-0.9	-0.6
Trunk predicted mass	5.9	33.5	76.4	-5.8	8.7	-3.5	7.1	5.5	-1.3	-7.8	-1.7
Standing height	8.2	81.3	146.4	-9.1	12.1	-6.5	11.1	10.2	-2.7	-12.0	-1.0
Length of working week for main job	1.7	1.9	4.0	1.4	-1.4	1.7	-2.0	-1.2	0.6	1.6	-0.6
Exposure to tobacco smoke at home	0.1	0.1	0.2	0.3	0.2	-0.1	0.2	-0.4	0.4	0.0	-0.4
Breastfed as a baby	7.3	9.0	16.3	-3.2	4.0	-2.2	3.6	3.7	-1.1	-3.6	0.4
Tense / ‘highly strung’	2.2	3.6	7.1	2.0	-2.7	1.1	-2.4	-2.2	0.0	2.4	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	3.0	4.5	10.0	2.3	-3.2	1.5	-2.6	-2.1	0.0	2.7	-0.2
Hair/balding pattern: Pattern 4	0.6	1.4	3.0	-1.0	0.7	-0.8	1.6	1.7	-1.1	-1.5	-0.3
Birth weight of first child	0.3	0.6	1.3	-1.0	0.8	-0.8	0.8	0.3	-0.3	-1.1	0.3
Peak expiratory flow (PEF)	0.5	1.2	5.2	-2.3	1.2	-0.4	0.7	0.6	-0.4	-1.0	-0.8
Pulse wave reflection index	0.2	0.3	0.6	-0.7	-0.4	-0.8	-0.3	-0.5	-0.8	0.3	-0.1
Ever highly irritable/argumentative for 2 days	4.7	5.6	11.5	2.4	-3.4	1.8	-2.7	-2.6	-0.4	3.2	-0.2
Loud music exposure frequency	0.6	0.6	2.9	-0.0	-0.1	-1.2	0.4	0.1	-0.9	-0.0	1.7
Qualifications: O levels/GCSEs or equivalent	12.6	20.1	37.3	-5.0	5.4	-3.4	4.9	6.1	-1.3	-5.7	0.2
Mouth/teeth dental problems: Bleeding gums	2.0	2.6	4.9	-2.1	1.4	-2.2	1.7	1.4	-0.6	-1.8	0.2
Blood clot in the leg (DVT)	5.7	7.3	11.8	3.4	-2.3	3.3	-3.4	-2.6	1.5	3.1	-1.0
Medication: Paracetamol	2.6	4.3	11.1	2.6	-3.3	0.6	-2.5	-1.9	0.5	2.5	0.3
Headache pain in last month	1.7	3.0	13.8	-0.2	-0.5	-2.5	1.1	0.8	-1.4	-0.4	3.7
Medication for cholesterol, blood pressure or diabetes	1.0	1.6	4.3	-0.6	2.1	0.7	0.4	1.3	0.4	-1.3	-2.1
Glaucoma (self-reported)	4.8	5.6	8.1	2.5	-2.8	2.8	-2.8	-2.5	0.7	2.6	-1.3
Gout (self-reported)	0.3	0.5	1.9	-1.4	0.5	-0.6	0.4	-0.1	0.2	-0.4	1.0
Hypothyroidism/myxoedema (self-reported)	6.4	12.6	21.4	-3.1	2.7	-4.6	3.7	3.1	-3.2	-3.5	4.2
Medication: Amlodipine	0.5	0.6	1.5	-0.7	-0.0	-1.2	0.9	0.4	-1.0	-0.6	0.9
Medication: Ventolin 100micrograms inhaler	3.4	4.4	7.9	1.6	-1.7	2.4	-2.8	-2.5	1.5	2.1	-1.8
Birth weight	1.3	2.9	5.7	-1.2	2.4	-1.2	1.9	2.2	0.4	-2.4	-0.2
Chronic bronchitis/emphysema (mother)	0.5	0.5	1.4	0.7	-0.5	0.9	-1.2	-0.6	-0.6	0.8	-0.3
High blood pressure (siblings)	0.6	0.9	4.0	1.5	0.6	0.7	-0.1	-0.5	2.0	0.0	-0.6
Forced vital capacity (FVC), Best measure	0.9	3.3	18.1	-0.9	1.4	1.7	-0.6	1.3	0.4	-0.8	-4.2
Body fat percentage	0.5	2.1	7.4	2.7	-1.9	0.8	-1.3	1.1	-0.3	1.4	0.2
Leg fat percentage (right)	1.4	5.1	12.9	3.6	-2.8	1.9	-2.4	-1.3	0.6	2.9	0.2
Arm fat-free mass (right)	3.9	20.1	45.9	-4.3	6.8	-2.7	5.5	4.2	-1.4	-6.1	-1.3
Exposure to tobacco smoke outside home	0.9	1.2	2.5	1.3	-1.6	0.7	-1.1	-1.3	0.1	1.3	-0.1
Comparative body size at age 10	2.1	5.8	10.0	-1.2	2.4	-3.1	2.7	3.2	-1.1	-2.6	2.3
Number of full brothers	0.3	0.3	0.9	-0.2	-0.9	-0.1	-0.6	-0.5	-0.9	0.5	0.3
Worry too long after embarrassment	0.4	0.7	3.7	-0.4	-0.4	-1.0	0.3	0.3	-1.9	-0.4	0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	1.6	0.7	-1.3	0.1	-0.7	-0.8	0.5	1.0	0.8
Wheeze or whistling in the chest in last year	1.2	2.2	5.9	1.0	-1.8	0.5	-1.6	-2.4	0.2	1.9	0.9
Number of children fathered	1.5	1.7	3.3	-1.1	1.6	0.2	1.3	1.0	1.8	-1.3	-1.3
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	1.2	-0.4	0.9	-0.0	0.4	1.1	-0.2	-0.7	-0.9
Age at first live birth	1.6	2.8	6.1	-1.6	2.5	-0.8	2.3	2.0	-0.3	-2.0	-0.1
Pulse wave peak to peak time	1.0	1.2	2.3	1.5	-0.9	1.4	-1.2	-0.5	1.4	0.9	-0.3
Health satisfaction	0.4	0.5	3.2	0.4	-0.4	0.0	-0.2	-0.1	-1.8	0.2	0.6
Shortness of breath walking on level ground	0.5	0.6	3.0	0.0	-0.7	-0.6	-0.1	-0.0	-1.7	0.2	1.1
Qualifications: College or University degree	8.5	26.7	39.1	-6.2	5.3	-5.2	6.2	5.5	-3.5	-6.0	1.8
Eye problems/disorders: None of the above	0.1	0.1	0.4	-0.3	0.6	0.6	0.2	0.2	0.2	0.1	-0.2
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.5	-0.7	0.1	-0.2	-0.0	-0.3	0.0	-0.3	-0.2
Emphysema/chronic bronchitis	1.1	1.3	2.4	1.2	-0.5	1.5	-1.2	-0.6	1.6	1.0	-0.9
Medication for pain relief, constipation, heartburn	4.1	7.1	17.2	-3.3	4.1	-0.5	2.8	2.8	0.3	-3.3	-1.2
Neck or shoulder pain in last month	0.7	1.0	3.1	-0.7	-0.8	-1.4	-0.0	-0.5	-1.1	0.1	1.8
Medication: Blood pressure	0.7	1.2	3.0	0.9	-1.7	-0.2	-0.7	-1.1	0.1	1.3	1.5
Angina (self-reported)	2.5	3.2	9.0	-1.2	0.8	-2.4	1.9	1.1	-1.6	-1.2	3.0
Migraine (self-reported)	0.3	0.3	0.9	0.2	-0.9	-0.5	-0.7	-0.6	-0.2	0.5	0.4
Medication: Ibuprofen	0.3	0.3	1.0	0.3	-0.7	-1.0	0.4	0.6	-0.2	-0.3	0.6
Medication: Allopurinol	0.3	0.3	1.5	-1.2	0.7	-0.4	0.3	-0.1	-0.2	-0.5	0.5
Medication: Omeprazole	2.4	2.9	7.0	0.7	-2.3	-0.9	-0.8	-1.5	-2.6	1.6	2.1
Medication: Seretide 50 evohaler	0.4	0.4	1.8	0.0	-0.3	-0.2	-0.4	-0.8	-0.4	0.7	1.3
Mean time to correctly identify matches	0.9	1.8	6.7	0.7	-1.9	-0.1	-0.4	0.1	-1.3	1.2	2.6
Heart disease (mother)	1.3	1.5	3.0	-1.4	1.0	-1.3	1.7	1.4	-0.9	-1.4	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.0	0.0	0.1	0.0	0.1	0.1	-0.0	-0.4	-0.1	0.0	-0.0
Whole body fat mass	0.2	1.0	5.2	0.7	0.6	-0.1	0.7	2.3	-0.7	-0.8	-0.3
Leg fat mass (right)	0.2	0.6	3.0	1.7	-0.3	0.7	-0.3	0.8	-0.1	0.3	-0.6
Arm predicted mass (right)	3.8	19.2	44.0	-4.2	6.6	-2.7	5.4	4.1	-1.5	-5.9	-1.4
Pulse rate, automated reading	0.2	0.8	3.0	0.9	-0.7	0.5	-0.2	-1.7	-0.9	0.9	0.0
Alcohol intake frequency.	5.5	12.8	21.5	4.6	-4.6	2.2	-4.1	-4.2	0.4	4.5	0.4
Comparative height size at age 10	11.6	63.8	106.1	-8.0	10.1	-7.0	10.0	8.9	-3.1	-10.3	0.8
Number of full sisters	0.5	0.6	1.8	0.5	0.5	0.6	-0.5	0.7	1.3	-0.1	-1.2
Suffer from ‘nerves’	0.3	0.5	1.0	0.4	-1.0	-0.7	-0.8	-0.9	-0.9	0.5	0.6
Overall health rating	0.8	1.7	3.4	1.4	-1.6	-0.3	-1.0	-1.6	-0.6	1.3	1.8
Chest pain or discomfort	0.4	0.6	1.1	-0.4	0.6	-0.6	1.1	0.6	-0.9	-0.9	0.9
Had major operations	0.5	0.5	1.0	-1.0	0.8	-0.4	0.9	0.7	0.0	-0.9	0.7
Age at last live birth	1.9	2.8	6.1	-1.6	2.5	-0.5	2.1	2.1	0.7	-2.0	-0.5
Family relationship satisfaction	0.1	0.2	1.1	0.1	-0.1	-0.2	-0.1	0.1	-1.0	-0.3	-0.2
Leg pain on walking	1.7	2.1	4.4	1.7	-2.1	1.1	-1.6	-1.6	0.0	1.7	0.0
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	1.2	0.6	-1.0	0.1	-1.1	-1.0	1.0	0.8	-0.1
Commuting to job workplace: Car/motor vehicle	4.0	4.6	7.9	1.9	-1.4	2.6	-2.8	-1.9	2.2	2.1	-1.8
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.1	-0.7	0.4	-0.7	1.0	-0.1	-0.3	-0.6	0.3
Medication: Aspirin	0.3	0.4	1.5	1.2	-0.5	-0.5	-0.2	-0.3	0.4	0.5	0.8
Supplements: Vitamin C	1.1	1.3	4.6	2.1	-1.4	0.5	-1.1	-0.8	0.1	1.2	0.1
Knee pain experienced in last month	3.9	6.0	9.4	2.8	-2.8	2.0	-2.8	-2.9	1.7	3.1	0.1
Hypertension (Self-reported)	0.7	1.9	3.8	1.2	-2.0	-0.4	-1.2	-1.8	-0.0	1.6	1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.6	3.0	5.1	1.6	-2.0	1.7	-2.1	-2.2	-0.1	2.2	-0.5
Illnesses of father: Heart disease	0.6	0.8	1.8	-1.3	1.2	-0.2	1.4	0.2	0.4	-1.0	-0.6
Illnesses of siblings: Diabetes	4.7	5.7	7.8	2.2	-2.2	2.6	-2.2	-2.6	2.8	2.4	-2.1
Smoking status: Previous	0.7	1.0	1.8	-1.3	1.0	0.3	1.2	1.0	0.3	-1.3	-1.1
Forced expiratory volume in 1-second (FEV1), predicted	2.3	4.8	10.1	-1.7	3.2	-1.6	2.4	2.7	-0.6	-3.1	-0.7
Whole body fat-free mass	5.2	29.5	64.5	-5.1	8.0	-3.4	6.6	5.7	-1.7	-7.3	-1.5
Leg fat-free mass (right)	4.6	24.8	48.4	-4.3	7.0	-3.1	5.9	6.2	-2.2	-6.6	-1.1
Arm fat percentage (left)	0.5	2.0	6.9	2.6	-1.8	0.8	-1.4	1.0	-0.3	1.4	0.2
Average weekly red wine intake	10.9	16.1	25.9	-4.9	4.3	-3.9	5.1	4.2	-1.4	-4.7	1.9
Handedness (chirality/laterality): Left-handed	0.8	1.0	2.4	0.3	-1.3	0.8	-1.2	-1.6	-0.3	1.3	-0.1
Mood swings	1.6	3.0	6.2	2.1	-2.5	-0.6	-1.3	-1.5	-1.4	1.6	2.0
Loneliness, isolation	0.8	1.1	1.8	0.4	-1.3	-0.5	-0.9	-1.3	-1.1	1.2	1.4
Long-standing illness, disability or infirmity	2.7	4.2	8.8	2.2	-3.0	1.3	-2.0	-2.8	0.1	2.4	0.7
Ever had bowel cancer screening	1.0	1.2	2.5	-1.6	0.7	-1.0	1.3	1.2	-0.3	-1.3	0.3
Diabetes diagnosed by doctor	1.6	2.6	8.3	1.1	-2.0	0.7	-1.6	-2.9	0.3	1.9	0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	1.9	-1.4	0.9	-0.3	0.8	0.9	0.4	-0.6	0.1
Friendships satisfaction	1.4	1.7	3.2	-1.0	0.6	-1.8	1.4	0.7	-1.8	-1.2	1.6
Qualifications: nursing, teaching	12.4	19.3	39.8	-4.2	4.2	-4.3	5.2	6.3	-1.8	-5.3	1.5
Commuting to job workplace: Walk	0.5	0.5	1.1	0.5	-1.0	0.3	-1.1	0.1	0.2	0.8	-0.9
Eye problems/disorders: Cataract	0.4	0.5	1.1	-0.2	0.5	-1.1	0.6	1.0	0.3	-0.8	0.7
Mouth/teeth dental problems: Mouth ulcers	2.6	4.1	9.5	0.4	-2.9	-0.3	-1.9	-3.1	-1.2	2.5	1.9
Medication for cholesterol	0.7	1.1	3.1	-0.5	1.1	0.1	0.1	1.7	-0.6	-0.9	-1.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	4.0	0.7	-1.1	-0.5	-0.4	-0.4	-0.5	0.9	2.0
Back pain experienced in last month	4.0	5.8	8.9	2.6	-2.7	2.5	-3.0	-2.4	1.1	2.9	-1.4
Mineral and other dietary supplements	0.8	1.1	2.9	-1.5	1.7	-0.7	0.7	1.1	-0.6	-0.9	0.5
Breast cancer (self-reported)	4.4	5.3	11.6	-2.8	2.0	-1.7	2.1	2.0	-3.4	-2.1	1.7
Asthma (self-reported)	3.8	7.6	19.3	1.9	-3.7	1.9	-2.8	-4.4	-0.6	3.5	0.5
Osteoporosis (self-reported)	0.2	0.2	0.6	0.5	-0.2	-0.0	-0.3	0.7	0.7	-0.0	0.6
Osteoarthritis (self-reported)	4.2	5.4	9.5	3.1	-2.4	2.5	-2.5	-2.4	1.1	2.8	-0.8
Medication: Aspirin	0.2	0.3	0.7	0.7	0.2	-0.9	0.6	0.4	0.2	-0.3	0.7
Medication: Gliclazide	1.3	1.5	4.8	0.7	-1.3	1.0	-1.2	-2.2	0.3	1.4	0.2
Illnesses of father: None of the above (group 1)	0.9	1.1	2.6	-0.6	0.8	-1.6	1.1	0.9	-1.2	-1.1	0.8
Smoking status: Current	1.0	1.6	3.7	0.8	-0.8	0.8	-1.2	-1.9	1.2	1.6	1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	4.5	9.5	22.2	2.6	-2.1	3.9	-3.3	-1.7	2.5	2.7	-4.7
Whole body water mass	5.3	30.0	65.9	-5.1	8.1	-3.4	6.6	5.8	-1.7	-7.4	-1.5
Leg predicted mass (right)	4.7	24.8	48.4	-4.3	7.0	-3.2	5.9	6.2	-2.2	-6.6	-1.0
Arm fat mass (left)	0.2	1.0	4.6	0.6	0.9	-0.1	0.7	2.2	-0.6	-0.9	-0.5
Number of self-reported non-cancer illnesses	2.3	4.0	8.8	1.4	-3.0	0.1	-1.4	-2.5	-0.4	2.3	2.8
Average weekly champagne plus white wine intake	1.1	1.5	2.3	-1.1	1.5	0.9	0.9	1.5	1.5	-0.9	-1.2
Miserableness	1.6	2.8	5.9	1.4	-2.4	-0.7	-1.3	-1.1	-2.1	1.4	2.1
Guilty feelings	1.1	1.6	5.2	-1.0	-0.8	-1.8	0.8	-0.1	-1.5	-0.1	2.3
Wears glasses or contact lenses	3.7	4.3	9.5	-1.3	2.2	-1.8	2.6	3.1	-1.0	-2.7	0.6
Ever taken oral contraceptive pill	1.5	1.7	4.2	-2.1	1.4	-0.3	1.1	1.5	-0.5	-1.4	-1.1
Hearing aid user	0.2	0.2	0.6	0.3	-0.4	0.0	0.2	-0.5	-0.8	0.4	0.8
Mother’s age at death	1.4	1.7	3.0	-1.0	1.4	-0.1	1.0	1.6	1.7	-1.5	-1.4
Financial situation satisfaction	3.3	4.1	7.2	1.9	-2.7	1.7	-2.6	-2.4	0.0	2.7	-0.4
Tinnitus: Yes, now most or all of the time	3.0	3.5	7.7	1.9	-2.8	1.7	-2.1	-2.1	-0.4	2.1	-0.5
Commuting to job workplace: Public transport	3.1	3.7	7.3	-1.3	1.2	-2.7	2.5	1.3	-1.5	-1.8	2.4
Eye problems/disorders: Glaucoma	1.4	1.7	3.3	1.0	-1.4	1.8	-1.4	-1.1	0.3	1.1	-1.6
Medication: Blood pressure	0.9	1.8	4.8	1.4	-1.6	0.4	-0.8	-2.2	0.7	1.5	1.1
Pain type(s) experienced in last month: Hip pain	0.7	0.9	1.7	-0.6	1.0	-1.3	1.0	1.0	-0.6	-1.0	1.0
Supplements: Fish oil (including cod liver oil)	1.2	1.5	2.5	1.6	-1.4	1.4	-1.0	-0.9	1.0	1.0	-1.3
High cholesterol (Self-reported)	2.3	4.1	15.3	-0.3	-2.5	-2.1	0.3	-1.4	-1.8	0.9	3.9
Medication: Bendroflumethiazide	0.7	1.1	2.7	1.0	-1.0	-0.1	-0.8	-1.2	1.6	0.9	1.2
Medication: Paracetamol	1.0	1.6	4.4	1.7	-2.1	-0.1	-1.5	-0.9	0.5	1.4	0.4
Medication: Lisinopril	2.4	3.1	6.8	1.0	-2.5	0.7	-1.8	-2.6	0.7	2.4	1.0
Medication: Atorvastatin	2.6	3.2	8.8	-1.5	0.5	-2.2	1.9	0.3	-2.2	-1.0	3.0
Illnesses of father: High blood pressure	0.5	0.6	1.2	1.0	-1.0	0.3	-0.9	-0.5	0.0	1.1	0.6
Alcohol drinker status: Never	7.6	9.1	14.3	3.7	-3.3	2.7	-3.8	-3.3	1.2	3.7	-0.8
Ever smoked	3.9	6.9	12.1	-3.5	3.4	-1.5	3.1	2.6	0.4	-3.5	-0.5
Basal metabolic rate	4.6	25.5	54.6	-4.5	7.4	-3.1	6.1	5.6	-1.7	-6.8	-1.4
Leg fat percentage (left)	2.0	7.2	15.9	4.0	-3.4	2.4	-2.9	-1.8	1.0	3.4	-0.2
Arm fat-free mass (left)	4.0	20.3	46.5	-4.3	6.8	-2.5	5.6	4.4	-1.3	-6.1	-1.6
Number of operations (self-reported)	0.7	1.0	4.9	-0.2	-1.1	-1.0	-0.0	-0.1	-0.6	0.4	2.2
Average weekly beer plus cider intake	1.0	1.4	4.3	0.9	-0.1	1.6	-1.2	-0.3	1.4	0.5	-2.1
Irritability	1.2	2.1	5.1	0.9	-2.2	-0.7	-1.8	-2.0	-0.5	1.6	0.7
Risk taking	0.7	1.0	4.7	0.3	0.1	0.9	-0.9	-1.1	2.2	0.5	-0.3
Ever had prostate specific antigen (PSA) test	1.9	2.2	3.5	-1.8	1.7	-1.2	1.9	1.7	0.2	-1.8	-0.3
Fractured/broken bones in last 5 years	3.3	4.3	7.7	-2.1	2.4	-2.3	2.8	1.7	-0.6	-2.2	1.8
Age started oral contraceptive pill	2.4	3.0	5.8	-1.4	2.0	-1.9	2.4	1.7	-1.0	-2.1	0.5
Diastolic blood pressure, automated reading	8.6	26.6	43.4	5.5	-6.4	3.8	-6.4	-6.3	1.5	6.6	-0.5
Ever depressed for a whole week	0.4	0.5	2.9	-0.9	-0.4	-0.2	0.2	0.1	-1.7	-0.0	0.6
Unable to work because of sickness or disability	0.7	0.9	2.0	0.4	-1.3	-0.9	-0.5	-0.5	-1.4	0.5	1.2
Commuting to job workplace: Cycle	0.8	0.9	1.8	-1.1	1.3	-0.6	1.3	0.9	0.3	-1.1	-0.3
Myopia	2.4	3.4	5.7	-2.1	1.5	-2.0	2.4	2.3	-0.8	-2.0	1.1
Vascular/heart problems diagnosed by doctor	0.8	2.3	3.9	-1.5	2.0	0.2	1.3	1.8	0.1	-1.8	-1.9
Cholesterol lowering medication	2.5	3.6	15.9	-0.1	-1.6	-2.0	0.7	-1.7	-1.7	0.6	4.0
Medication: Omeprazole (e.g. Zanprol)	2.7	3.3	7.5	1.2	-2.7	-0.0	-1.4	-2.3	-1.8	2.3	1.4
Pain experienced in last month	2.1	3.6	7.5	-2.7	2.3	-1.4	2.3	1.4	-1.1	-2.3	-0.1
Supplements: Calcium	5.1	5.6	9.5	-2.1	1.9	-2.5	3.1	1.7	-2.5	-2.6	2.2
Basal cell carcinoma (self-reported)	0.4	0.5	2.0	-1.2	0.3	0.1	0.2	0.3	0.1	-0.5	-1.4
Heart attack/myocardial infarction (self-reported)	0.7	0.9	2.1	1.2	-0.1	0.9	-0.6	-1.4	1.4	0.7	-0.8
Deep venous thrombosis (DVT) (self-reported)	6.4	8.2	13.5	3.7	-2.4	3.4	-3.5	-2.8	1.8	3.3	-1.0
Heart disease (siblings)	2.1	2.6	4.9	2.1	-2.2	1.1	-1.7	-1.8	1.3	1.6	-0.4
Alcohol drinker status: Previous	0.4	0.4	1.3	-0.5	-0.4	-0.9	0.4	0.3	-0.8	0.1	1.1
Pack years of smoking	0.2	0.3	1.3	0.9	-0.3	-0.5	-0.2	-0.3	-0.2	0.3	1.1
Impedance of whole body	0.6	3.0	10.7	1.8	-3.3	0.3	-2.1	-0.3	0.2	2.2	1.1
Leg fat mass (left)	0.2	0.9	3.8	1.9	-0.6	1.0	-0.6	0.6	0.1	0.6	-0.8
Arm predicted mass (left)	4.0	20.2	47.8	-4.2	6.9	-2.4	5.5	4.4	-1.1	-6.1	-1.6