[Hub]/) : Traits : Qualifications: nursing, teaching : ←

chr12:122,713,991-124,591,385

Best TWAS P=2.85e-10 · Best GWAS P=1.05e-07 conditioned to 0.273

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	CDK2AP1	0.20	0.18	lasso	11	0.19	1.0e-15	5.3	-5.1	3.0e-07	-0.98	0.03	0.97	FALSE
2	GTEx	Adipose Subcutaneous	RP11-282O18.3	0.15	0.14	lasso	7	0.15	2.0e-12	5.1	-5.2	1.7e-07	-0.98	0.03	0.97	FALSE
3	GTEx	Adipose Visceral Omentum	RP11-282O18.3	0.14	0.11	enet	12	0.10	6.7e-06	4.7	-5.1	3.1e-07	-0.92	0.07	0.93	FALSE
4	GTEx	Artery Aorta	CDK2AP1	0.17	0.19	lasso	2	0.15	8.0e-09	5.3	-5.3	9.8e-08	-1.00	0.04	0.96	FALSE
5	GTEx	Artery Aorta	RP11-282O18.3	0.18	0.19	lasso	9	0.16	4.3e-09	5.3	-5.1	2.8e-07	-0.99	0.06	0.94	FALSE
6	GTEx	Artery Tibial	ABCB9	0.04	0.02	lasso	2	0.01	3.0e-02	4.9	5.1	3.1e-07	0.89	0.07	0.88	FALSE
7	GTEx	Breast Mammary Tissue (Female)	CDK2AP1	0.08	0.03	lasso	3	0.02	6.4e-02	4.9	-5.2	1.7e-07	-0.93	0.06	0.52	FALSE
8	GTEx	Breast Mammary Tissue (Female)	RP11-282O18.3	0.09	0.07	enet	8	0.08	2.8e-03	4.7	-5.2	2.6e-07	-0.95	0.09	0.75	FALSE
9	GTEx	Cells Transformed fibroblasts	OGFOD2	0.10	0.07	lasso	7	0.07	3.1e-06	5.1	5.3	1.1e-07	0.89	0.06	0.94	FALSE
10	GTEx	Cells Transformed fibroblasts	C12orf65	0.07	0.05	lasso	4	0.04	5.8e-04	4.5	-5.1	2.7e-07	-0.89	0.06	0.89	FALSE
11	GTEx	Cells Transformed fibroblasts	ABCB9	0.08	0.12	enet	7	0.12	4.3e-09	5.2	5.5	3.2e-08	0.83	0.05	0.94	FALSE
12	GTEx	Cells Transformed fibroblasts	SETD8	0.10	0.12	enet	9	0.09	1.4e-07	4.5	5.2	2.1e-07	0.87	0.06	0.94	FALSE
13	GTEx	Colon Transverse	ABCB9	0.08	0.07	enet	5	0.09	5.3e-05	5.2	5.4	6.5e-08	0.92	0.05	0.92	FALSE
14	GTEx	Esophagus Mucosa	ABCB9	0.10	0.03	lasso	5	0.05	5.4e-04	4.7	5.2	2.5e-07	0.89	0.06	0.92	FALSE
15	GTEx	Liver	ABCB9	0.32	0.32	lasso	3	0.28	1.9e-08	5.2	5.2	2.5e-07	0.73	0.04	0.95	FALSE
16	GTEx	Muscle Skeletal	SETD8	0.16	0.02	lasso	4	0.03	3.8e-04	5.2	6.3	2.8e-10	0.91	0.03	0.96	TRUE
17	GTEx	Nerve Tibial	ABCB9	0.06	0.04	lasso	3	0.05	3.5e-04	5.2	5.2	1.7e-07	0.98	0.05	0.94	FALSE
18	GTEx	Pancreas	ARL6IP4	0.07	0.07	lasso	2	0.07	9.6e-04	5.1	-5.4	7.8e-08	-0.93	0.06	0.79	FALSE
19	GTEx	Pancreas	SETD8	0.20	0.12	lasso	5	0.13	3.4e-06	5.3	-5.3	9.9e-08	-0.98	0.03	0.97	FALSE
20	GTEx	Pancreas	RP11-282O18.3	0.22	0.24	lasso	5	0.24	2.3e-10	5.3	-5.2	1.9e-07	-0.99	0.03	0.96	FALSE
21	GTEx	Skin Not Sun Exposed Suprapubic	ABCB9	0.13	0.15	lasso	11	0.11	2.1e-06	5.2	5.3	1.3e-07	0.81	0.05	0.95	FALSE
22	GTEx	Skin Sun Exposed Lower leg	ABCB9	0.09	0.08	lasso	5	0.08	4.3e-07	5.2	5.2	1.5e-07	0.77	0.04	0.96	FALSE
23	GTEx	Stomach	MPHOSPH9	0.17	0.08	lasso	5	0.10	1.2e-05	4.8	5.2	1.6e-07	0.96	0.08	0.90	FALSE
24	GTEx	Testis	MPHOSPH9	0.28	0.27	enet	23	0.32	1.3e-14	4.7	5.2	1.6e-07	0.94	0.12	0.87	FALSE
25	GTEx	Testis	CDK2AP1	0.20	0.14	lasso	5	0.13	2.0e-06	5.2	-5.2	1.7e-07	-0.82	0.04	0.95	FALSE
26	GTEx	Thyroid	MPHOSPH9	0.10	0.08	enet	20	0.09	2.0e-07	4.7	5.2	1.6e-07	0.91	0.13	0.86	FALSE
27	The Cancer Genome Atlas	Colon Adenocarcinoma	RILPL2	0.09	0.09	blup	43	0.08	3.1e-05	5.2	5.6	1.9e-08	0.88	0.01	0.99	FALSE
28	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ABCB9	0.06	0.06	enet	7	0.07	5.2e-08	5.1	5.1	2.8e-07	0.80	0.00	0.99	FALSE
29	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CDK2AP1	0.04	0.04	lasso	3	0.03	3.8e-04	5.3	-5.3	1.3e-07	-1.00	0.01	0.97	FALSE
30	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CDK2AP1	0.12	0.14	blup	34	0.15	7.2e-07	5.1	-5.2	2.0e-07	-0.95	0.02	0.98	FALSE
31	The Cancer Genome Atlas	Prostate Adenocarcinoma	ARL6IP4	0.03	0.04	blup	17	0.04	1.6e-05	5.1	-5.2	2.4e-07	-0.78	0.00	0.99	FALSE
32	The Cancer Genome Atlas	Prostate Adenocarcinoma	CDK2AP1	0.06	0.07	lasso	2	0.06	1.7e-06	5.3	-5.2	2.5e-07	-1.00	0.00	0.99	FALSE
33	The Cancer Genome Atlas	Stomach Adenocarcinoma	CDK2AP1	0.09	0.10	lasso	2	0.10	1.8e-07	5.3	-5.4	5.2e-08	-0.99	0.00	0.99	FALSE
34	The Cancer Genome Atlas	Testicular Germ Cell Tumors	CDK2AP1	0.13	0.10	blup	34	0.11	8.2e-05	5.2	-5.2	1.7e-07	-0.94	0.01	0.96	FALSE
35	The Cancer Genome Atlas	Thyroid Carcinoma	CDK2AP1	0.08	0.10	lasso	2	0.10	1.3e-09	5.3	-5.2	1.7e-07	-1.00	0.00	1.00	FALSE