Best TWAS P=2.82e-09 · Best GWAS P=4.8e-11 conditioned to 9.67e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Not Sun Exposed Suprapubic | ELOVL7 | 0.14 | 0.09 | lasso | 3 | 0.08 | 6.3e-05 | -5.1 | 5.9 | 2.8e-09 | -0.57 | 0.22 | 0.18 | TRUE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | ERCC8 | 0.04 | 0.01 | blup | 39 | 0.01 | 8.1e-03 | -2.8 | -5.1 | 2.9e-07 | 0.67 | 0.00 | 0.65 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ERCC8 | 0.06 | 0.04 | lasso | 1 | 0.02 | 2.3e-03 | -5.2 | -5.2 | 2.1e-07 | 0.62 | 0.00 | 0.98 | FALSE |