53 significantly associated models · 21 unique genes
.
# | chr | p0 | p1 | # assoc genes | # joint genes | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
---|---|---|---|---|---|---|---|---|---|---|
1 | 1 | 71163715 | 73435171 | 1 | 1 | 1.1e-09 | 5.0e-07 | 9.9e-02 | 89 | NEGR1 |
2 | 1 | 201169554 | 202607593 | 1 | 1 | 2.3e-07 | 5.6e-08 | 1.0e+00 | 100 | LMOD1 |
3 | 1 | 242723236 | 244345666 | 1 | 1 | 2.7e-07 | 4.5e-05 | 1.0e-01 | 84 | SDCCAG8 |
4 | 3 | 49030828 | 50800146 | 6 | 1 | 2.8e-08 | 1.2e-06 | 9.3e-01 | 100 | TRAIP |
5 | 3 | 84767271 | 86367480 | 1 | 1 | 6.6e-08 | 5.3e-06 | 4.8e-02 | 81 | CADM2 |
6 | 5 | 59353199 | 60833080 | 2 | 1 | 2.8e-09 | 4.8e-11 | 9.7e-05 | 65 | ELOVL7 |
7 | 12 | 122713991 | 124591385 | 9 | 1 | 2.8e-10 | 1.1e-07 | 2.7e-01 | 96 | SETD8 |
Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|---|---|---|---|
GTEx | Small Intestine Terminal Ileum | 0 | 0.000 | 1.8 |
GTEx | Adipose Visceral Omentum | 2 | 0.098 | 1.7 |
GTEx | Brain Cerebellar Hemisphere | 1 | 0.067 | 1.7 |
GTEx | Brain Hypothalamus | 0 | 0.000 | 1.7 |
GTEx | Breast Mammary Tissue | 0 | 0.000 | 1.7 |
GTEx | Cells EBV-transformed lymphocytes | 0 | 0.000 | 1.7 |
GTEx | Colon Transverse | 1 | 0.048 | 1.7 |
GTEx | Esophagus Muscularis | 1 | 0.031 | 1.7 |
GTEx | Ovary | 0 | 0.000 | 1.7 |
GTEx | Skin Not Sun Exposed Suprapubic | 2 | 0.081 | 1.7 |
GTEx | Spleen | 0 | 0.000 | 1.7 |
GTEx | Stomach | 1 | 0.069 | 1.7 |
GTEx | Testis | 3 | 0.095 | 1.7 |
GTEx | Uterus | 0 | 0.000 | 1.7 |
GTEx | Vagina | 0 | 0.000 | 1.7 |
The Cancer Genome Atlas | Soft Tissue Sarcoma | 0 | 0.000 | 1.7 |
GTEx | Artery Aorta | 2 | 0.067 | 1.6 |
GTEx | Artery Coronary | 0 | 0.000 | 1.6 |
GTEx | Artery Tibial | 2 | 0.053 | 1.6 |
GTEx | Brain Cerebellum | 0 | 0.000 | 1.6 |
GTEx | Brain Cortex | 0 | 0.000 | 1.6 |
GTEx | Brain Frontal Cortex BA9 | 0 | 0.000 | 1.6 |
GTEx | Brain Hippocampus | 0 | 0.000 | 1.6 |
GTEx | Brain Nucleus accumbens basal ganglia | 0 | 0.000 | 1.6 |
GTEx | Brain Putamen basal ganglia | 0 | 0.000 | 1.6 |
GTEx | Breast Mammary Tissue (Male) | 0 | 0.000 | 1.6 |
GTEx | Breast Mammary Tissue (Female) | 2 | 0.122 | 1.6 |
GTEx | Cells Transformed fibroblasts | 4 | 0.095 | 1.6 |
GTEx | Colon Sigmoid | 0 | 0.000 | 1.6 |
GTEx | Esophagus Gastroesophageal Junction | 0 | 0.000 | 1.6 |
GTEx | Esophagus Mucosa | 1 | 0.030 | 1.6 |
GTEx | Heart Atrial Appendage | 1 | 0.063 | 1.6 |
GTEx | Heart Left Ventricle | 0 | 0.000 | 1.6 |
GTEx | Liver | 1 | 0.139 | 1.6 |
GTEx | Lung | 0 | 0.000 | 1.6 |
GTEx | Muscle Skeletal | 1 | 0.035 | 1.6 |
GTEx | Nerve Tibial | 1 | 0.023 | 1.6 |
GTEx | Pancreas | 4 | 0.245 | 1.6 |
GTEx | Pituitary | 0 | 0.000 | 1.6 |
GTEx | Prostate | 0 | 0.000 | 1.6 |
GTEx | Skin Sun Exposed Lower leg | 1 | 0.027 | 1.6 |
GTEx | Thyroid | 1 | 0.025 | 1.6 |
ROSMAP | Brain Pre-frontal Cortex | 1 | 0.023 | 1.6 |
The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Esophageal Carcinoma | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | 1 | 0.090 | 1.6 |
The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | 3 | 0.120 | 1.6 |
The Cancer Genome Atlas | Rectum Adenocarcinoma | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Stomach Adenocarcinoma | 1 | 0.059 | 1.6 |
GTEx | Adipose Subcutaneous | 2 | 0.057 | 1.5 |
GTEx | Adrenal Gland | 0 | 0.000 | 1.5 |
GTEx | Brain Caudate basal ganglia | 0 | 0.000 | 1.5 |
GTEx | Whole Blood | 0 | 0.000 | 1.5 |
METSIM | Adipose | 1 | 0.022 | 1.5 |
NTR | Blood | 0 | 0.000 | 1.5 |
YFS | Blood | 0 | 0.000 | 1.5 |
CommonMind | Brain Pre-frontal Cortex | 1 | 0.019 | 1.5 |
The Cancer Genome Atlas | Bladder Urothelial Carcinoma | 0 | 0.000 | 1.5 |
The Cancer Genome Atlas | Breast Invasive Carcinoma | 0 | 0.000 | 1.5 |
The Cancer Genome Atlas | Colon Adenocarcinoma | 1 | 0.048 | 1.5 |
The Cancer Genome Atlas | Glioblastoma Multiforme | 0 | 0.000 | 1.5 |
The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | 0 | 0.000 | 1.5 |
The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | 0 | 0.000 | 1.5 |
The Cancer Genome Atlas | Brain Lower Grade Glioma | 2 | 0.046 | 1.5 |
The Cancer Genome Atlas | Lung Adenocarcinoma | 1 | 0.034 | 1.5 |
The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | 0 | 0.000 | 1.5 |
The Cancer Genome Atlas | Pancreatic Adenocarcinoma | 1 | 0.060 | 1.5 |
The Cancer Genome Atlas | Testicular Germ Cell Tumors | 1 | 0.078 | 1.5 |
The Cancer Genome Atlas | Thyroid Carcinoma | 2 | 0.039 | 1.5 |
The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | 0 | 0.000 | 1.5 |
The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | 0 | 0.000 | 1.4 |
The Cancer Genome Atlas | Prostate Adenocarcinoma | 3 | 0.065 | 1.4 |
The Cancer Genome Atlas | Skin Cutaneous Melanoma | 0 | 0.000 | 1.4 |