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chr19:17,473,015-18,902,592

Best TWAS P=4.82e-12 · Best GWAS P=1.06e-10 conditioned to 0.885

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	The Cancer Genome Atlas	Brain Lower Grade Glioma	IL12RB1	0.05	0.03	lasso	3	0.03	1.3e-04	-6.2	6.9	4.8e-12	-0.94	0.00	0.99	TRUE
3	The Cancer Genome Atlas	Breast Invasive Carcinoma	IL12RB1	0.06	0.03	lasso	5	0.05	3.9e-10	-6.3	6.8	1.5e-11	-0.84	0.00	1.00	FALSE
4	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	IL12RB1	0.05	0.03	enet	11	0.05	2.3e-06	4.4	6.7	2.5e-11	-0.79	0.00	0.99	FALSE
1	METSIM	Adipose	IL12RB1	0.05	0.05	lasso	3	0.04	2.8e-07	-6.2	6.4	2.1e-10	-0.97	0.00	1.00	FALSE
2	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	IL12RB1	0.07	0.02	lasso	3	0.01	6.4e-02	-6.2	6.3	2.2e-10	-0.97	0.00	0.97	FALSE
7	The Cancer Genome Atlas	Lung Adenocarcinoma	IL12RB1	0.10	0.08	enet	13	0.07	3.9e-08	-6.1	6.3	2.5e-10	-0.89	0.00	1.00	FALSE
11	The Cancer Genome Atlas	Thyroid Carcinoma	IL12RB1	0.08	0.04	lasso	3	0.05	8.9e-06	-4.1	6.1	9.2e-10	-0.84	0.00	0.99	FALSE
10	The Cancer Genome Atlas	Testicular Germ Cell Tumors	IL12RB1	0.10	0.01	enet	10	0.06	2.6e-03	-6.3	5.9	3.6e-09	-0.71	0.01	0.73	FALSE
5	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IL12RB1	0.10	0.08	blup	58	0.09	6.9e-10	-6.1	5.9	4.1e-09	-0.89	0.00	1.00	FALSE
9	The Cancer Genome Atlas	Prostate Adenocarcinoma	IL12RB1	0.09	0.01	blup	58	0.05	1.2e-05	-6.5	5.7	9.6e-09	-0.81	0.00	1.00	FALSE
8	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	IL12RB1	0.07	0.04	blup	58	0.06	4.9e-07	-3.8	5.7	1.1e-08	-0.82	0.01	0.99	FALSE