Best TWAS P=7.24e-11 · Best GWAS P=1.68e-07 conditioned to 0.929
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Not Sun Exposed Suprapubic | C11orf49 | 0.09 | 0.00 | enet | 12 | 0.03 | 6.0e-03 | 5.2 | -6.5 | 7.2e-11 | -0.79 | 0.02 | 0.91 | TRUE |
| 2 | GTEx | Spleen | LRP4 | 0.15 | 0.14 | lasso | 5 | 0.12 | 6.5e-04 | 5.1 | -5.1 | 2.8e-07 | -0.96 | 0.02 | 0.87 | FALSE |
| 3 | GTEx | Thyroid | C11orf49 | 0.09 | 0.05 | lasso | 3 | 0.04 | 3.0e-04 | 5.1 | -5.2 | 1.8e-07 | -0.99 | 0.02 | 0.98 | FALSE |
| 4 | GTEx | Uterus | C11orf49 | 0.24 | 0.24 | lasso | 13 | 0.24 | 1.3e-05 | 5.2 | -5.2 | 1.9e-07 | -0.99 | 0.02 | 0.86 | FALSE |
| 5 | YFS | Blood | NR1H3 | 0.34 | 0.15 | enet | 66 | 0.24 | 3.1e-76 | -3.9 | 5.6 | 2.1e-08 | 0.58 | 0.78 | 0.13 | FALSE |