[Hub]/) : Traits : Vascular/heart problems diagnosed by doctor :

chr1:26,428,864-28,406,173

Best TWAS P=5.91e-10 · Best GWAS P=3.73e-08 conditioned to 0.681

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Esophagus Muscularis PIGV 0.09 0.07 enet 25 0.13 3.4e-08 -4.1 5.4 5.5e-08 0.16 0.70 0.23 TRUE
2 GTEx Thyroid ZDHHC18 0.11 0.10 lasso 4 0.13 4.2e-10 -5.2 -5.2 2.2e-07 -0.11 0.02 0.98 FALSE
3 ROSMAP Brain Pre-frontal Cortex CD164L2 0.16 0.13 bslmm 220 0.16 2.4e-20 4.5 5.4 5.8e-08 0.19 0.19 0.80 FALSE
4 YFS Blood ZDHHC18 0.08 0.11 bslmm 286 0.11 2.1e-33 -5.2 -5.2 2.5e-07 -0.12 0.01 0.98 FALSE
5 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CD164L2 0.04 0.06 blup 36 0.06 9.2e-08 4.8 5.4 6.1e-08 0.37 0.04 0.95 FALSE
6 The Cancer Genome Atlas Prostate Adenocarcinoma WASF2 0.03 0.04 lasso 3 0.03 3.2e-04 4.9 5.2 2.5e-07 0.22 0.03 0.94 FALSE
7 The Cancer Genome Atlas Thyroid Carcinoma FCN3 0.03 0.03 blup 35 0.02 8.0e-03 4.9 -6.2 5.9e-10 -0.71 0.01 0.82 TRUE
8 The Cancer Genome Atlas Thyroid Carcinoma PIGV 0.04 0.04 lasso 4 0.04 2.1e-04 -5.2 5.2 1.8e-07 0.14 0.00 0.97 FALSE
9 The Cancer Genome Atlas Thyroid Carcinoma ZDHHC18 0.34 0.42 enet 5 0.41 8.1e-43 -5.2 -5.2 2.0e-07 -0.14 0.00 1.00 FALSE