Best TWAS P=5.91e-10 · Best GWAS P=3.73e-08 conditioned to 0.681
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | PIGV | 0.09 | 0.07 | enet | 25 | 0.13 | 3.4e-08 | -4.1 | 5.4 | 5.5e-08 | 0.16 | 0.70 | 0.23 | TRUE |
| 2 | GTEx | Thyroid | ZDHHC18 | 0.11 | 0.10 | lasso | 4 | 0.13 | 4.2e-10 | -5.2 | -5.2 | 2.2e-07 | -0.11 | 0.02 | 0.98 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | CD164L2 | 0.16 | 0.13 | bslmm | 220 | 0.16 | 2.4e-20 | 4.5 | 5.4 | 5.8e-08 | 0.19 | 0.19 | 0.80 | FALSE |
| 4 | YFS | Blood | ZDHHC18 | 0.08 | 0.11 | bslmm | 286 | 0.11 | 2.1e-33 | -5.2 | -5.2 | 2.5e-07 | -0.12 | 0.01 | 0.98 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CD164L2 | 0.04 | 0.06 | blup | 36 | 0.06 | 9.2e-08 | 4.8 | 5.4 | 6.1e-08 | 0.37 | 0.04 | 0.95 | FALSE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | WASF2 | 0.03 | 0.04 | lasso | 3 | 0.03 | 3.2e-04 | 4.9 | 5.2 | 2.5e-07 | 0.22 | 0.03 | 0.94 | FALSE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | FCN3 | 0.03 | 0.03 | blup | 35 | 0.02 | 8.0e-03 | 4.9 | -6.2 | 5.9e-10 | -0.71 | 0.01 | 0.82 | TRUE |
| 8 | The Cancer Genome Atlas | Thyroid Carcinoma | PIGV | 0.04 | 0.04 | lasso | 4 | 0.04 | 2.1e-04 | -5.2 | 5.2 | 1.8e-07 | 0.14 | 0.00 | 0.97 | FALSE |
| 9 | The Cancer Genome Atlas | Thyroid Carcinoma | ZDHHC18 | 0.34 | 0.42 | enet | 5 | 0.41 | 8.1e-43 | -5.2 | -5.2 | 2.0e-07 | -0.14 | 0.00 | 1.00 | FALSE |