[Hub]/) : Traits : Vascular/heart problems diagnosed by doctor : ← →

chr1:42,542,658-43,978,837

Best TWAS P=5.41e-08 · Best GWAS P=6.23e-08 conditioned to 0.0845

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	GTEx	Brain Nucleus accumbens basal ganglia	RP5-994D16.9	0.27	0.03	lasso	5	0.01	2.0e-01	-5.4	-5.4	5.4e-08	0.81	0.02	0.62	TRUE
4	GTEx	Brain Cerebellar Hemisphere	CCDC23	0.34	0.26	lasso	4	0.22	2.6e-06	-4.5	-5.4	5.6e-08	0.82	0.06	0.81	FALSE
9	ROSMAP	Brain Pre-frontal Cortex	C1orf50	0.18	0.22	lasso	6	0.24	4.6e-30	-5.3	5.4	7.3e-08	-0.97	0.00	1.00	FALSE
3	GTEx	Brain Cerebellar Hemisphere	C1orf50	0.32	0.20	enet	37	0.21	4.8e-06	-5.4	5.3	1.1e-07	-0.78	0.01	0.97	FALSE
8	GTEx	Lung	C1orf50	0.09	0.07	lasso	3	0.06	4.8e-05	-5.2	5.3	1.2e-07	-0.97	0.00	1.00	FALSE
1	GTEx	Adipose Subcutaneous	CCDC23	0.13	0.17	lasso	4	0.17	1.4e-13	-5.4	-5.3	1.3e-07	0.99	0.00	1.00	FALSE
2	GTEx	Adipose Visceral Omentum	CCDC23	0.23	0.11	enet	15	0.18	9.5e-10	-4.4	-5.3	1.3e-07	0.86	0.01	0.98	FALSE
6	GTEx	Breast Mammary Tissue (Female)	CCDC23	0.18	0.06	lasso	5	0.04	2.1e-02	-5.2	-5.2	1.7e-07	1.00	0.01	0.94	FALSE
11	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C1orf50	0.06	0.02	blup	42	0.04	4.1e-03	-5.2	5.2	1.8e-07	-0.88	0.00	0.95	FALSE
13	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	C1orf50	0.17	0.05	lasso	4	0.03	3.3e-02	-5.2	5.2	1.8e-07	-0.99	0.00	0.94	FALSE
12	The Cancer Genome Atlas	Brain Lower Grade Glioma	C1orf50	0.08	0.09	blup	42	0.10	2.0e-11	-5.2	5.2	2.2e-07	-0.92	0.00	1.00	FALSE
7	GTEx	Colon Transverse	C1orf50	0.20	0.20	enet	13	0.16	3.7e-08	-5.2	5.2	2.4e-07	-0.93	0.00	0.99	FALSE
10	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CCDC23	0.04	0.05	enet	6	0.05	3.2e-06	-5.4	-5.1	2.9e-07	0.98	0.01	0.99	FALSE