[Hub]/) : Traits : Vascular/heart problems diagnosed by doctor : ← →

chr1:42,542,658-43,978,837

Best TWAS P=5.41e-08 · Best GWAS P=6.23e-08 conditioned to 0.0845

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous CCDC23 0.13 0.17 lasso 4 0.17 1.4e-13 -5.4 -5.3 1.3e-07 0.99 0.00 1.00 FALSE
2 GTEx Adipose Visceral Omentum CCDC23 0.23 0.11 enet 15 0.18 9.5e-10 -4.4 -5.3 1.3e-07 0.86 0.01 0.98 FALSE
3 GTEx Brain Cerebellar Hemisphere C1orf50 0.32 0.20 enet 37 0.21 4.8e-06 -5.4 5.3 1.1e-07 -0.78 0.01 0.97 FALSE
4 GTEx Brain Cerebellar Hemisphere CCDC23 0.34 0.26 lasso 4 0.22 2.6e-06 -4.5 -5.4 5.6e-08 0.82 0.06 0.81 FALSE
5 GTEx Brain Nucleus accumbens basal ganglia RP5-994D16.9 0.27 0.03 lasso 5 0.01 2.0e-01 -5.4 -5.4 5.4e-08 0.81 0.02 0.62 TRUE
6 GTEx Breast Mammary Tissue (Female) CCDC23 0.18 0.06 lasso 5 0.04 2.1e-02 -5.2 -5.2 1.7e-07 1.00 0.01 0.94 FALSE
7 GTEx Colon Transverse C1orf50 0.20 0.20 enet 13 0.16 3.7e-08 -5.2 5.2 2.4e-07 -0.93 0.00 0.99 FALSE
8 GTEx Lung C1orf50 0.09 0.07 lasso 3 0.06 4.8e-05 -5.2 5.3 1.2e-07 -0.97 0.00 1.00 FALSE
9 ROSMAP Brain Pre-frontal Cortex C1orf50 0.18 0.22 lasso 6 0.24 4.6e-30 -5.3 5.4 7.3e-08 -0.97 0.00 1.00 FALSE
10 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CCDC23 0.04 0.05 enet 6 0.05 3.2e-06 -5.4 -5.1 2.9e-07 0.98 0.01 0.99 FALSE
11 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma C1orf50 0.06 0.02 blup 42 0.04 4.1e-03 -5.2 5.2 1.8e-07 -0.88 0.00 0.95 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma C1orf50 0.08 0.09 blup 42 0.10 2.0e-11 -5.2 5.2 2.2e-07 -0.92 0.00 1.00 FALSE
13 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma C1orf50 0.17 0.05 lasso 4 0.03 3.3e-02 -5.2 5.2 1.8e-07 -0.99 0.00 0.94 FALSE