[Hub]/) : Traits : Vascular/heart problems diagnosed by doctor : ← →

chr11:99,859,184-101,559,718

Best TWAS P=4.62e-36 · Best GWAS P=1.4e-34 conditioned to 0.135

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	GTEx	Artery Tibial	TMEM133	0.26	0.25	enet	28	0.27	1.3e-21	12.3	12.5	4.6e-36	0.94	0.00	1.00	TRUE
4	GTEx	Artery Tibial	ARHGAP42	0.24	0.24	lasso	4	0.24	2.4e-18	12.3	12.2	1.8e-34	0.98	0.00	1.00	FALSE
2	GTEx	Artery Aorta	ARHGAP42	0.22	0.15	enet	18	0.19	1.7e-10	11.6	11.2	6.2e-29	0.86	0.00	1.00	FALSE
3	GTEx	Artery Aorta	TMEM133	0.30	0.15	enet	34	0.19	7.1e-11	12.3	10.2	2.3e-24	0.72	0.00	1.00	FALSE
8	The Cancer Genome Atlas	Breast Invasive Carcinoma	ARHGAP42	0.04	0.01	blup	266	0.02	1.1e-04	-6.4	8.4	6.3e-17	0.57	0.04	0.88	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ARHGAP42	0.08	0.03	enet	14	0.05	2.8e-06	6.6	6.5	9.4e-11	0.50	0.98	0.00	FALSE
6	GTEx	Cells Transformed fibroblasts	ARHGAP42	0.15	0.10	enet	20	0.08	2.6e-06	-5.3	6.2	6.2e-10	0.46	0.71	0.23	FALSE
7	ROSMAP	Brain Pre-frontal Cortex	ARHGAP42	0.04	0.00	lasso	2	0.00	1.9e-01	6.2	6.0	2.5e-09	0.51	0.11	0.19	FALSE