[Hub]/) : Traits : Vascular/heart problems diagnosed by doctor : ← →

chr11:99,859,184-101,559,718

Best TWAS P=4.62e-36 · Best GWAS P=1.4e-34 conditioned to 0.135

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ARHGAP42 0.08 0.03 enet 14 0.05 2.8e-06 6.6 6.5 9.4e-11 0.50 0.98 0.00 FALSE
2 GTEx Artery Aorta ARHGAP42 0.22 0.15 enet 18 0.19 1.7e-10 11.6 11.2 6.2e-29 0.86 0.00 1.00 FALSE
3 GTEx Artery Aorta TMEM133 0.30 0.15 enet 34 0.19 7.1e-11 12.3 10.2 2.3e-24 0.72 0.00 1.00 FALSE
4 GTEx Artery Tibial ARHGAP42 0.24 0.24 lasso 4 0.24 2.4e-18 12.3 12.2 1.8e-34 0.98 0.00 1.00 FALSE
5 GTEx Artery Tibial TMEM133 0.26 0.25 enet 28 0.27 1.3e-21 12.3 12.5 4.6e-36 0.94 0.00 1.00 TRUE
6 GTEx Cells Transformed fibroblasts ARHGAP42 0.15 0.10 enet 20 0.08 2.6e-06 -5.3 6.2 6.2e-10 0.46 0.71 0.23 FALSE
7 ROSMAP Brain Pre-frontal Cortex ARHGAP42 0.04 0.00 lasso 2 0.00 1.9e-01 6.2 6.0 2.5e-09 0.51 0.11 0.19 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma ARHGAP42 0.04 0.01 blup 266 0.02 1.1e-04 -6.4 8.4 6.3e-17 0.57 0.04 0.88 FALSE