TWAS hub - C1orf50

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.1020	0.0430	2.9e-03	0.046	NA	0.017	NA	0.022	1.5e-03	NA	3.7e-02	NA	2.2e-02
2	GTEx	Brain Caudate basal ganglia	0.2210	0.0750	9.7e-04	0.131	NA	0.045	NA	0.116	1.3e-04	NA	2.0e-02	NA	3.2e-04
3	GTEx	Brain Cerebellar Hemisphere	0.3190	0.0900	6.7e-05	0.197	NA	0.208	NA	0.196	8.7e-06	NA	4.8e-06	NA	9.5e-06
4	GTEx	Brain Cerebellum	0.3160	0.1040	1.1e-04	0.074	NA	0.073	NA	0.093	3.2e-03	NA	3.5e-03	NA	1.1e-03
5	GTEx	Brain Cortex	0.3670	0.1030	8.0e-05	0.136	NA	0.062	NA	0.129	1.4e-04	NA	8.5e-03	NA	2.0e-04
6	GTEx	Brain Frontal Cortex BA9	0.3431	0.0806	2.5e-06	0.245	NA	0.078	NA	0.231	3.8e-07	NA	4.3e-03	NA	8.6e-07
7	GTEx	Brain Hypothalamus	0.3000	0.1110	1.7e-03	0.109	NA	0.058	NA	0.099	1.7e-03	NA	1.8e-02	NA	2.6e-03
8	GTEx	Brain Nucleus accumbens basal ganglia	0.2500	0.0850	9.1e-04	0.171	NA	0.127	NA	0.140	2.5e-05	NA	2.8e-04	NA	1.4e-04
9	GTEx	Breast Mammary Tissue (Male)	0.0204	0.0600	4.0e-01	-0.011	NA	-0.013	NA	-0.010	6.7e-01	NA	9.4e-01	NA	6.6e-01
10	GTEx	Breast Mammary Tissue (Female)	0.0728	0.0646	1.4e-01	-0.006	NA	-0.001	NA	0.034	5.5e-01	NA	3.4e-01	NA	3.4e-02
11	GTEx	Colon Transverse	0.2030	0.0570	3.0e-06	0.197	NA	0.162	NA	0.140	1.1e-09	NA	3.7e-08	NA	3.5e-07
12	GTEx	Esophagus Muscularis	0.0780	0.0360	7.5e-03	0.098	NA	0.058	NA	0.074	1.6e-06	NA	2.0e-04	NA	3.0e-05
13	GTEx	Lung	0.0862	0.0305	2.9e-04	0.072	NA	0.029	NA	0.055	3.6e-06	NA	2.6e-03	NA	4.8e-05
14	GTEx	Nerve Tibial	0.1403	0.0392	4.8e-08	0.094	NA	0.154	NA	0.153	3.8e-07	NA	4.6e-11	NA	5.9e-11
15	GTEx	Pituitary	0.2880	0.0930	1.1e-03	0.085	NA	0.109	NA	0.143	3.7e-03	NA	1.1e-03	NA	1.9e-04
16	GTEx	Skin Not Sun Exposed Suprapubic	0.1330	0.0500	2.7e-04	0.052	NA	0.032	NA	0.023	7.6e-04	NA	6.7e-03	NA	1.9e-02
17	GTEx	Spleen	0.2980	0.1070	2.2e-03	0.146	NA	0.068	NA	0.146	1.4e-04	NA	8.3e-03	NA	1.4e-04
18	GTEx	Thyroid	0.0800	0.0330	2.4e-03	0.011	NA	0.011	NA	0.014	4.7e-02	NA	4.6e-02	NA	2.8e-02
19	ROSMAP	Brain Pre-frontal Cortex	0.1765	0.0337	0.0e+00	0.219	0.183	0.233	0.223	0.237	1.0e-27	5.3e-23	1.5e-29	3e-28	4.6e-30
20	TCGA	Kidney Renal Clear Cell Carcinoma	0.0665	0.0261	5.7e-08	0.068	0.069	0.063	NA	0.066	4.2e-08	3.0e-08	1.4e-07	NA	5.8e-08
21	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0630	0.0410	1.8e-03	0.021	0.035	0.021	NA	0.028	2.2e-02	4.1e-03	2.1e-02	NA	9.2e-03
22	TCGA	Brain Lower Grade Glioma	0.0769	0.0290	8.2e-13	0.090	0.100	0.093	NA	0.095	2.2e-10	2.0e-11	1.0e-10	NA	5.9e-11
23	TCGA	Lung Adenocarcinoma	0.1017	0.0554	3.3e-03	0.008	0.005	0.036	NA	0.020	3.2e-02	6.9e-02	4.5e-05	NA	1.7e-03
24	TCGA	Pheochromocytoma and Paraganglioma	0.1680	0.0770	1.0e-03	0.048	0.017	0.000	NA	0.026	5.3e-03	6.8e-02	3.1e-01	NA	3.3e-02
25	TCGA	Thyroid Carcinoma	0.0760	0.0340	3.6e-07	0.066	0.081	0.032	NA	0.068	5.3e-07	2.7e-08	3.8e-04	NA	3.6e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25
Vascular/heart problems diagnosed by doctor	7.5	20.4	28.9	4.7	4.8	5.3	5.0	4.4	4.1	5.1	4.8	1.2	3.5	5.2	4.2	5.3	4.9	2.5	4.9	3.6	4.3	5.4	5.1	5.2	5.2	2.5	5.2	3.7
Hypertension (Self-reported)	6.7	18.6	25.7	-4.5	-4.6	-5.0	-4.5	-4.2	-3.9	-4.9	-4.4	-0.8	-3.8	-4.8	-4.3	-5.0	-4.7	-2.5	-4.7	-3.6	-4.2	-5.1	-4.8	-5.1	-5.0	-1.6	-4.9	-3.7
High blood pressure	6.3	17.5	26.1	-4.3	-4.4	-5.1	-4.4	-4.0	-3.7	-4.8	-4.3	-0.7	-3.5	-4.7	-4.1	-4.9	-4.5	-2.4	-4.6	-3.4	-3.9	-5.0	-4.6	-5.0	-4.8	-1.9	-4.8	-3.5
Medication: Atenolol	5.2	6.6	12.0	-3.4	-3.4	-1.8	-3.1	-3.0	-2.2	-3.1	-2.4	-0.4	-1.0	-2.6	-1.5	-2.7	-3.2	-1.4	-2.4	-1.7	-3.5	-3.0	-3.3	-2.3	-2.8	-1.0	-3.0	-2.4
Medication: Blood pressure	4.9	8.7	13.5	-3.0	-3.0	-2.7	-3.2	-2.5	-2.0	-3.4	-2.9	0.3	-2.3	-3.7	-2.8	-3.5	-3.3	-0.9	-3.5	-2.2	-3.2	-3.6	-3.5	-3.4	-3.6	-2.0	-3.5	-2.5
Medication: Lisinopril	4.6	5.9	12.6	-2.4	-2.5	-2.8	-2.4	-2.2	-2.1	-3.5	-3.1	-1.9	-1.4	-2.7	-1.8	-3.0	-2.4	-0.9	-3.2	-1.1	-2.8	-2.6	-2.6	-2.8	-2.5	-0.9	-2.8	-2.2
Medication for cholesterol, blood pressure or diabetes	4.4	7.3	12.1	2.6	2.7	3.1	3.0	2.2	1.9	2.9	2.6	-0.6	2.2	3.4	2.7	3.2	3.2	0.9	3.5	2.1	2.9	3.2	3.1	3.1	3.2	1.9	3.1	2.0
Cardiovascular Disease	4.2	14.0	19.7	-4.2	-4.3	-4.4	-4.3	-3.8	-3.3	-4.3	-3.9	-0.7	-3.0	-4.1	-3.6	-4.1	-4.3	-1.9	-3.9	-2.6	-3.7	-4.3	-4.3	-4.2	-4.2	-1.3	-4.2	-3.2
Stomach or abdominal pain in last month	4.2	5.2	9.5	-2.3	-2.3	-2.5	-2.1	-2.5	-2.9	-2.2	-2.4	0.6	-1.6	-2.1	-1.9	-2.2	-2.8	-3.0	-1.7	-3.1	-2.1	-2.7	-2.1	-2.3	-2.2	-1.6	-2.5	-2.1
High blood pressure (siblings)	4.2	6.0	9.4	-3.1	-3.0	-1.9	-2.5	-2.8	-2.4	-2.7	-2.4	-1.3	-2.1	-2.5	-2.6	-2.1	-2.8	-1.7	-1.9	-1.9	-2.9	-3.0	-2.8	-2.7	-2.7	-0.5	-2.7	-2.6
Qualifications: NVQ or HND or HNC or equivalent	4.1	5.0	8.0	2.3	2.4	2.7	2.0	2.6	2.5	2.7	2.8	0.7	0.8	2.8	1.4	2.5	2.0	2.1	2.4	2.1	1.6	2.3	2.5	2.2	2.4	1.2	2.6	2.2
Medication: Blood pressure	4.0	7.7	11.1	-3.2	-3.2	-3.3	-2.8	-3.2	-3.1	-3.3	-2.9	-1.6	-2.2	-2.3	-2.4	-2.8	-2.9	-2.0	-2.7	-2.3	-3.2	-3.3	-3.0	-3.2	-2.9	-0.5	-3.0	-2.3
Crohns Disease (2012)	3.8	6.1	9.4	2.9	2.8	1.5	2.6	2.9	2.6	2.5	2.1	-0.9	2.5	2.5	2.5	2.3	3.0	2.3	1.8	3.1	2.4	2.9	2.6	2.6	2.9	1.3	2.5	2.4
Emphysema/chronic bronchitis	3.8	4.3	7.6	-2.1	-2.1	-2.2	-1.9	-2.3	-2.6	-2.0	-2.8	0.4	-1.9	-1.9	-2.0	-2.0	-2.4	-2.1	-1.7	-2.6	-1.6	-2.6	-2.1	-2.2	-2.3	-0.3	-2.3	-1.2
Waist circumference	3.4	12.6	19.4	-3.7	-3.7	-3.9	-4.4	-3.8	-3.2	-3.7	-4.1	-4.4	-1.1	-3.3	-2.1	-4.2	-3.4	-2.5	-3.0	-2.7	-3.4	-3.9	-3.9	-3.3	-3.7	-3.5	-4.2	-3.8
Worry (Nagel 2018)	3.3	7.0	13.5	2.6	2.7	2.7	3.3	2.9	2.5	3.2	3.3	3.7	0.5	3.1	1.3	3.4	2.1	1.1	3.4	1.5	1.8	2.7	3.0	2.6	2.9	1.7	3.1	2.2
Medication: Cholesterol lowering	3.2	5.0	8.0	-2.1	-2.2	-2.5	-2.8	-2.1	-2.1	-2.1	-2.2	-0.1	-1.5	-2.8	-1.8	-2.6	-2.7	-0.7	-2.7	-1.6	-2.6	-2.8	-2.5	-2.3	-2.6	-1.6	-2.6	-1.8
Arm fat percentage (right)	3.1	12.2	22.2	-3.8	-3.8	-3.2	-4.7	-3.7	-3.1	-4.3	-3.8	-3.4	-0.5	-3.5	-1.4	-4.4	-3.0	-1.9	-3.5	-2.1	-4.0	-3.8	-4.1	-3.1	-3.6	-2.7	-4.4	-3.7
Wears glasses or contact lenses	3.1	3.6	6.8	2.4	2.3	2.3	1.8	2.1	1.0	1.3	1.4	1.5	1.7	2.1	2.0	1.9	2.6	1.1	-0.2	1.3	2.2	2.2	2.2	2.2	2.2	1.0	2.0	1.9
Hair/balding pattern: Pattern 2	3.0	3.8	7.9	-1.7	-1.7	-1.8	-1.6	-2.3	-2.8	-2.0	-2.2	-1.9	-1.6	-1.9	-1.9	-1.8	-2.4	-2.3	-1.8	-2.4	-1.3	-1.9	-1.8	-2.2	-2.1	-0.3	-1.8	-1.6
Weight	2.9	14.1	20.6	-4.0	-4.0	-4.2	-4.5	-3.8	-3.1	-4.1	-4.3	-4.5	-1.1	-3.5	-2.0	-4.5	-3.4	-2.4	-3.1	-2.6	-4.1	-4.1	-4.3	-3.5	-4.0	-3.2	-4.5	-4.5
Arm fat mass (left)	2.9	12.1	20.7	-3.7	-3.7	-3.6	-4.5	-3.6	-3.0	-4.2	-4.0	-4.0	-0.4	-3.3	-1.3	-4.3	-2.9	-2.1	-3.4	-2.1	-3.8	-3.8	-4.0	-3.1	-3.5	-2.8	-4.4	-4.1
Arm fat mass (right)	2.8	11.4	19.6	-3.6	-3.6	-3.3	-4.4	-3.5	-2.8	-4.1	-3.7	-3.8	-0.5	-3.3	-1.4	-4.2	-2.8	-1.9	-3.3	-2.0	-3.8	-3.7	-4.0	-3.1	-3.5	-2.6	-4.3	-4.0
Whole body fat mass	2.7	11.1	19.5	-3.4	-3.5	-3.3	-4.4	-3.6	-3.2	-3.9	-3.9	-3.9	-0.5	-3.2	-1.4	-4.1	-3.0	-2.0	-3.5	-2.0	-3.7	-3.5	-3.7	-3.0	-3.3	-2.7	-4.1	-3.6
Arm fat percentage (left)	2.7	10.6	19.4	-3.5	-3.5	-3.1	-4.4	-3.4	-2.9	-4.0	-3.6	-3.4	-0.4	-3.1	-1.3	-4.0	-2.9	-1.8	-3.3	-2.0	-3.7	-3.5	-3.8	-2.9	-3.4	-2.7	-4.0	-3.5
Alcohol drinker status: Previous	2.7	3.0	7.0	2.3	2.2	1.2	1.9	1.7	0.3	2.0	1.5	2.6	0.2	2.1	0.9	2.1	1.6	0.6	0.1	0.9	2.4	1.9	2.5	1.6	2.0	0.8	2.2	1.9
Trunk fat mass	2.6	11.1	20.4	-3.5	-3.5	-3.3	-4.5	-3.5	-3.1	-3.9	-3.9	-3.8	-0.5	-3.2	-1.4	-4.1	-3.1	-1.8	-3.5	-1.9	-3.7	-3.6	-3.8	-2.9	-3.4	-2.8	-4.0	-3.5
Leg fat mass (right)	2.6	10.0	18.6	-3.3	-3.4	-3.0	-4.2	-3.5	-3.0	-3.8	-3.7	-4.3	-0.0	-2.9	-0.9	-4.0	-2.5	-2.0	-3.1	-1.7	-3.4	-3.3	-3.5	-2.7	-3.0	-2.4	-4.0	-3.8
Leg fat mass (left)	2.5	9.9	19.7	-3.2	-3.3	-2.9	-4.1	-3.5	-3.0	-3.7	-3.7	-4.4	-0.3	-2.9	-1.2	-3.9	-2.6	-1.9	-3.1	-1.8	-3.4	-3.3	-3.5	-2.8	-3.0	-2.4	-3.9	-3.7
Ever highly irritable/argumentative for 2 days	2.4	2.9	6.1	1.5	1.4	0.7	1.7	1.6	1.8	2.2	1.4	0.7	0.8	1.7	1.1	2.0	1.6	2.5	1.7	2.2	1.6	1.8	1.6	2.2	1.8	-0.8	2.0	2.5
Body mass index (BMI)	2.3	9.8	16.2	-3.2	-3.3	-3.2	-3.9	-3.3	-2.8	-3.6	-3.6	-4.0	-0.5	-2.8	-1.4	-3.9	-2.6	-2.0	-3.0	-2.0	-3.5	-3.3	-3.5	-2.9	-3.2	-2.2	-3.9	-3.7
Hip circumference	2.3	10.1	17.0	-3.2	-3.2	-3.5	-3.9	-3.2	-2.6	-3.4	-3.5	-4.1	-1.7	-2.7	-2.3	-3.5	-3.2	-2.5	-3.1	-2.7	-3.2	-3.3	-3.4	-3.1	-3.3	-1.6	-3.5	-4.1
Body fat percentage	2.3	9.2	18.3	-3.1	-3.1	-2.9	-4.3	-3.3	-3.1	-3.7	-3.5	-3.5	-0.3	-2.8	-1.1	-3.7	-2.7	-1.6	-3.7	-1.7	-3.4	-3.2	-3.3	-2.5	-3.0	-2.2	-3.7	-3.1
Worry too long after embarrassment	2.3	3.9	10.5	1.8	1.9	2.2	2.1	2.0	1.7	1.8	2.8	2.7	0.5	2.5	1.1	2.4	2.1	1.0	1.1	1.5	1.3	2.1	2.1	1.8	2.0	3.2	2.3	1.0
Illnesses of father: Heart disease	2.3	3.2	7.7	1.6	1.6	2.2	2.0	1.4	1.5	2.1	1.3	-0.6	2.6	1.6	2.6	1.8	1.5	1.0	2.8	1.8	1.8	1.8	1.8	2.4	2.1	0.7	1.4	1.1
Medication for cholesterol	2.3	3.6	8.1	2.3	2.2	1.8	2.1	1.9	1.6	2.9	1.9	1.5	1.2	1.9	1.3	2.2	1.8	1.0	2.1	1.3	1.7	2.1	2.2	2.1	2.1	-0.2	2.1	1.9
Average weekly champagne plus white wine intake	2.3	3.2	5.9	-2.1	-2.2	-1.7	-1.6	-2.2	-2.0	-1.1	-1.5	1.1	-1.1	-2.1	-1.5	-1.5	-1.8	-2.4	0.6	-2.3	-2.2	-2.0	-1.8	-1.8	-1.7	-1.9	-1.9	-1.0
Medication: Omeprazole (e.g. Zanprol)	2.2	2.6	5.2	-1.3	-1.3	-2.1	-1.7	-1.4	-1.5	-1.5	-0.6	-1.5	-1.5	-2.3	-1.9	-1.8	-2.0	-0.8	-1.8	-1.8	-1.2	-1.8	-1.7	-1.8	-2.1	-0.3	-1.7	-1.6
LDL Cholesterol	2.1	3.3	6.2	-2.0	-2.1	-2.5	-1.7	-1.8	-1.3	-1.8	-2.3	-1.3	-1.8	-2.0	-1.9	-1.8	-1.5	-1.3	-1.7	-1.6	-1.9	-1.9	-2.0	-2.1	-2.1	-1.3	-1.8	-1.4
Leg fat-free mass (left)	2.1	11.1	18.1	-3.7	-3.8	-3.5	-3.7	-3.5	-2.5	-3.4	-3.9	-2.8	-1.3	-3.2	-2.0	-4.0	-3.1	-2.5	-1.9	-2.6	-3.8	-3.7	-4.0	-3.3	-3.6	-2.9	-4.1	-4.2
Townsend deprivation index at recruitment	2.1	2.9	5.3	-1.6	-1.6	-1.1	-2.1	-1.8	-1.9	-1.6	-1.8	-1.2	-0.7	-1.9	-1.1	-2.3	-1.8	-1.1	-1.2	-1.5	-2.1	-2.1	-1.9	-1.8	-1.9	-1.3	-2.3	-2.0
Leg predicted mass (left)	2.1	11.1	18.1	-3.7	-3.8	-3.5	-3.8	-3.5	-2.6	-3.4	-3.9	-2.8	-1.3	-3.2	-2.0	-4.0	-3.1	-2.6	-1.9	-2.6	-3.8	-3.7	-4.0	-3.3	-3.6	-2.8	-4.1	-4.3
Hair/balding pattern: Pattern 4	2.1	5.1	9.1	2.5	2.6	2.2	2.9	2.6	2.4	2.8	3.0	1.9	0.7	2.3	1.5	2.5	2.0	2.4	2.1	2.0	2.0	2.4	2.3	2.3	2.1	-0.8	2.6	2.1
Leg fat-free mass (right)	2.1	11.1	17.8	-3.7	-3.8	-3.5	-3.6	-3.5	-2.5	-3.3	-3.9	-2.8	-1.5	-3.2	-2.2	-3.9	-3.2	-2.4	-1.8	-2.6	-3.9	-3.7	-4.0	-3.3	-3.7	-2.9	-4.1	-4.2
Leg predicted mass (right)	2.1	11.1	17.6	-3.7	-3.8	-3.5	-3.7	-3.5	-2.5	-3.3	-3.9	-2.8	-1.5	-3.3	-2.2	-4.0	-3.2	-2.4	-1.8	-2.6	-3.9	-3.8	-4.0	-3.3	-3.7	-2.9	-4.1	-4.2
Basal metabolic rate	2.1	11.9	20.1	-3.7	-3.8	-4.0	-3.9	-3.5	-2.6	-3.6	-4.0	-3.8	-1.2	-3.3	-2.0	-4.1	-3.1	-2.6	-2.3	-2.5	-3.7	-3.8	-4.0	-3.4	-3.6	-2.8	-4.2	-4.5
Trunk fat percentage	2.0	7.8	16.1	-2.9	-2.9	-2.7	-4.0	-3.0	-2.8	-3.5	-3.3	-2.9	-0.3	-2.6	-1.1	-3.4	-2.6	-1.4	-3.5	-1.5	-3.2	-3.0	-3.1	-2.3	-2.8	-2.2	-3.4	-2.6
Medication: Omeprazole	2.0	2.4	5.1	-1.2	-1.3	-2.3	-1.3	-1.4	-1.7	-1.5	-0.7	-0.7	-1.7	-2.1	-2.0	-1.5	-1.9	-1.1	-1.6	-2.0	-0.8	-1.6	-1.4	-1.8	-1.9	0.2	-1.4	-1.5
Medication: Aspirin	2.0	2.6	5.0	-1.6	-1.7	-1.6	-1.3	-1.8	-1.8	-1.3	-1.4	0.2	-1.2	-1.7	-1.5	-1.7	-2.2	-1.6	-0.8	-1.9	-1.8	-1.8	-1.7	-1.6	-2.0	-1.0	-1.8	-2.1
Eye problems/disorders: Glaucoma	2.0	2.3	4.4	1.6	1.6	1.5	1.4	1.6	1.8	1.8	1.7	0.7	2.1	1.6	2.0	1.2	2.1	0.3	1.9	0.8	1.9	1.5	1.5	1.9	1.7	0.1	1.0	0.5
Unable to work because of sickness or disability	2.0	2.6	4.5	1.9	1.9	1.9	1.0	2.0	1.8	1.2	1.4	0.7	1.5	1.7	1.7	1.4	1.6	2.0	0.5	2.1	1.9	1.8	1.7	1.8	1.9	-0.0	1.6	1.7
Neuroticism (Nagel 2018)	1.8	4.3	8.1	2.0	2.2	2.8	1.5	2.5	2.2	1.8	2.7	2.9	1.7	2.4	2.1	2.2	2.1	2.0	1.5	2.5	0.8	1.8	2.0	2.2	2.4	0.4	1.9	1.7
Hayfever, allergic rhinitis or eczema	1.8	3.9	9.0	1.9	1.9	2.8	2.1	1.3	0.7	2.3	2.2	-0.2	1.4	3.0	1.8	2.7	1.5	0.8	1.8	1.1	2.0	2.3	2.4	2.4	2.2	0.8	2.5	1.9
Frequency of tenseness / restlessness in last 2 weeks	1.8	2.8	6.6	1.8	1.8	2.0	1.6	1.2	0.8	2.2	1.8	2.6	0.9	1.9	1.3	2.0	1.4	0.2	1.7	0.8	1.7	1.9	2.2	2.0	2.0	0.0	2.0	1.2
Angina (self-reported)	1.8	2.3	8.3	-1.7	-1.7	-1.1	-2.3	-1.6	-1.3	-1.5	-2.0	-1.8	1.0	-1.4	0.5	-1.7	-1.3	-0.8	-1.4	-0.5	-1.5	-1.4	-1.8	-0.5	-1.1	-2.9	-1.8	-0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.8	2.1	4.0	-1.7	-1.7	-1.2	-1.5	-1.5	-0.9	-1.4	-1.2	-0.1	-1.2	-2.0	-1.7	-1.5	-1.7	-0.5	-0.8	-1.2	-1.6	-2.0	-1.8	-1.6	-1.9	-0.4	-1.8	-1.3
Guilty feelings	1.8	2.7	5.2	1.2	1.2	2.3	0.7	1.7	2.1	1.7	2.3	1.8	2.2	1.7	2.1	1.5	2.2	1.4	1.1	1.6	0.7	1.6	1.2	2.2	1.7	-0.8	1.3	0.6
Leg fat percentage (left)	1.8	6.6	18.9	-2.4	-2.5	-2.4	-3.6	-2.8	-2.6	-3.1	-3.0	-4.3	0.1	-2.1	-0.7	-3.2	-1.9	-1.5	-3.0	-1.3	-2.6	-2.6	-2.6	-2.0	-2.3	-1.7	-3.1	-3.0
Ever had prostate specific antigen (PSA) test	1.8	2.1	6.2	-1.4	-1.3	-2.0	-1.3	-1.1	-0.9	-1.1	-1.1	-0.5	-2.5	-1.3	-2.4	-1.1	-1.3	-0.9	-1.7	-1.7	-1.1	-1.6	-1.4	-1.9	-1.8	0.3	-1.1	-1.0
Allergy or Eczema	1.7	4.6	10.8	2.3	2.3	2.4	2.8	1.6	0.8	2.5	2.6	0.2	0.8	3.3	1.5	3.1	1.5	0.8	1.9	1.0	2.6	2.5	2.6	2.4	2.4	0.8	2.9	1.7
Leg fat percentage (right)	1.7	6.1	17.9	-2.3	-2.4	-2.3	-3.5	-2.7	-2.5	-3.0	-2.9	-4.2	0.5	-2.0	-0.2	-3.1	-1.6	-1.6	-3.0	-1.2	-2.3	-2.4	-2.5	-1.8	-2.0	-1.6	-3.0	-3.0
Medication: Allopurinol	1.7	2.2	5.7	-1.0	-0.9	-1.5	-1.3	-1.3	-1.8	-1.0	-1.6	-0.1	-2.4	-1.4	-2.4	-1.1	-2.3	-1.4	-2.2	-1.7	-0.8	-1.4	-0.9	-2.1	-1.4	0.4	-1.0	0.1
Illness, injury, bereavement, stress in last 2 years	1.7	2.1	4.5	1.7	1.5	1.1	2.1	1.5	1.1	1.7	1.1	0.8	0.6	1.7	0.9	1.7	1.0	0.8	0.8	0.9	1.8	1.7	1.8	1.5	1.6	1.7	1.8	1.7
Medication: Aspirin	1.7	2.3	4.9	-1.4	-1.5	-1.3	-1.2	-1.7	-1.9	-1.3	-1.3	0.1	-0.8	-1.6	-1.1	-1.5	-2.1	-1.8	-0.8	-1.8	-1.8	-1.7	-1.6	-1.4	-1.7	-0.8	-1.7	-2.2
Whole body fat-free mass	1.7	9.7	17.5	-3.3	-3.4	-3.7	-3.4	-3.1	-2.3	-3.1	-3.6	-3.5	-1.3	-3.0	-1.9	-3.7	-2.8	-2.5	-1.8	-2.4	-3.3	-3.4	-3.6	-3.1	-3.3	-2.6	-3.8	-4.2
Arm fat-free mass (left)	1.7	8.8	16.7	-3.0	-3.1	-3.6	-3.2	-2.9	-2.2	-3.0	-3.3	-4.1	-1.1	-2.7	-1.8	-3.6	-2.5	-2.2	-2.1	-2.1	-2.9	-3.2	-3.3	-3.1	-3.0	-2.2	-3.6	-4.0
Depression (Nagel 2018)	1.6	2.4	4.6	1.3	1.5	1.9	1.1	1.4	1.3	1.8	2.0	1.2	1.2	1.9	1.4	2.1	1.4	1.3	1.6	1.6	0.7	1.5	1.7	2.0	1.9	-0.7	1.7	1.3
Medication: Co-codamol	1.6	1.8	4.0	-0.9	-0.8	-2.0	-0.9	-1.1	-1.6	-0.9	-1.7	-1.9	-1.8	-1.7	-1.8	-1.1	-1.9	-1.0	-1.6	-1.3	-0.4	-1.4	-0.8	-1.5	-1.2	-0.5	-1.2	-0.4
Leg pain on walking	1.6	2.0	4.1	-1.0	-1.1	-1.6	-1.9	-1.0	-1.1	-1.3	-1.6	-1.7	-0.5	-1.6	-0.8	-2.0	-1.0	-0.9	-1.5	-1.3	-1.7	-1.7	-1.3	-1.6	-1.4	-0.9	-1.9	-1.3
Whole body water mass	1.6	9.0	16.7	-3.2	-3.3	-3.6	-3.3	-3.0	-2.1	-3.0	-3.5	-3.5	-1.1	-2.9	-1.8	-3.6	-2.6	-2.3	-1.7	-2.2	-3.2	-3.2	-3.5	-2.9	-3.2	-2.6	-3.7	-4.1
Arm predicted mass (left)	1.6	8.3	19.4	-2.9	-3.0	-3.5	-3.2	-2.8	-2.1	-2.9	-3.2	-4.4	-1.1	-2.6	-1.7	-3.5	-2.4	-2.0	-1.9	-1.9	-2.8	-3.1	-3.2	-2.9	-2.9	-2.1	-3.5	-3.9
Crohns Disease (2017)	1.5	3.3	7.8	1.9	1.8	0.9	1.6	1.7	1.8	1.8	1.2	0.3	2.8	1.6	2.7	1.2	2.6	0.9	1.7	2.1	1.9	2.0	1.5	2.3	2.2	-2.2	1.3	1.1
Hypothyroidism (self reported)	1.5	3.5	10.2	1.8	1.6	1.0	1.1	1.7	2.1	1.7	1.0	-1.8	3.2	2.0	3.1	0.9	2.4	1.6	1.4	2.3	2.2	2.0	1.5	2.7	1.9	0.3	1.2	0.4
Average weekly spirits intake	1.5	1.8	5.2	-1.4	-1.4	-1.5	-1.6	-1.4	-1.1	-1.6	-1.4	-2.3	0.1	-1.4	-0.4	-1.6	-0.8	-0.0	-0.9	-0.3	-0.9	-1.6	-1.6	-1.4	-1.4	-1.8	-1.8	-1.0
Pulse rate	1.5	2.4	8.7	1.6	1.3	1.3	0.9	1.3	1.2	1.3	0.7	0.5	3.0	1.5	2.5	0.8	1.8	2.3	0.5	2.4	1.2	1.5	1.1	2.0	1.6	-1.4	0.9	1.7
Medication: Amlodipine	1.5	2.2	4.6	-1.6	-1.7	-1.5	-1.5	-1.2	-0.9	-2.0	-1.9	-0.5	-0.0	-2.0	-0.4	-1.7	-1.1	0.3	-2.1	-0.3	-1.4	-1.7	-2.0	-1.3	-1.6	-1.8	-1.9	-0.6
Arm fat-free mass (right)	1.5	7.5	15.8	-2.9	-3.0	-3.4	-3.0	-2.7	-1.9	-2.7	-3.1	-4.0	-1.1	-2.4	-1.7	-3.2	-2.3	-1.9	-1.7	-1.8	-2.8	-2.9	-3.1	-2.8	-2.8	-2.5	-3.2	-3.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.5	1.8	6.7	1.2	1.3	1.5	2.0	1.1	0.9	1.0	1.3	0.2	-0.4	1.8	0.0	1.9	0.7	1.2	0.6	0.7	1.5	1.2	1.5	1.1	0.9	2.6	1.7	1.6
Friendships satisfaction	1.5	1.9	3.4	1.7	1.7	1.8	0.8	1.5	1.2	1.7	1.3	-0.0	1.4	1.8	1.3	1.5	1.2	0.9	1.2	0.9	1.1	1.5	1.6	1.6	1.6	-0.5	1.4	1.1
Number of self-reported non-cancer illnesses	1.5	2.5	5.2	-1.6	-1.6	-1.3	-2.1	-1.3	-0.9	-2.0	-1.2	-0.6	-0.5	-2.0	-0.8	-2.3	-1.5	0.5	-1.9	-0.7	-1.9	-2.1	-2.1	-1.7	-2.0	-1.4	-2.2	-1.1
Fractured/broken bones in last 5 years	1.5	2.0	5.0	1.7	1.8	1.3	1.9	1.0	-0.2	1.8	0.8	-0.4	-0.6	2.0	-0.3	2.2	0.7	0.8	1.1	0.3	1.2	1.5	2.1	1.3	1.2	0.7	2.2	2.1
Blood White Count	1.4	10.1	24.3	2.6	2.9	3.7	2.1	2.9	3.7	3.4	3.5	2.3	4.9	3.3	4.5	2.8	3.5	2.2	4.1	3.0	2.7	2.9	2.5	4.2	3.5	-1.2	2.2	2.0
Angina	1.4	1.9	8.6	-1.5	-1.5	-0.8	-2.1	-1.4	-1.1	-1.3	-1.7	-1.7	1.3	-1.4	0.8	-1.6	-1.0	-0.6	-1.2	-0.2	-1.3	-1.2	-1.6	-0.3	-0.8	-2.9	-1.6	-0.7
Qualifications: CSEs or equivalent	1.4	1.8	4.9	-1.2	-1.1	-1.6	-1.8	-0.9	-1.1	-1.8	-1.3	-1.6	-0.9	-1.6	-1.1	-1.7	-0.6	0.4	-2.2	-0.1	-1.1	-1.6	-1.6	-1.6	-1.5	-1.0	-1.6	-0.8
Trunk fat-free mass	1.4	8.1	15.3	-3.0	-3.1	-3.6	-3.0	-2.7	-1.9	-2.8	-3.2	-3.7	-1.1	-2.8	-1.7	-3.5	-2.4	-2.2	-1.7	-2.2	-2.8	-3.0	-3.3	-2.8	-3.0	-2.4	-3.4	-3.9
Trunk predicted mass	1.4	7.9	15.1	-2.9	-3.0	-3.5	-2.9	-2.7	-1.9	-2.8	-3.1	-3.7	-1.2	-2.7	-1.7	-3.4	-2.4	-2.2	-1.6	-2.1	-2.8	-3.0	-3.3	-2.8	-3.0	-2.4	-3.4	-3.9
Blood clot in the leg (DVT)	1.4	1.7	4.0	-1.3	-1.3	-1.1	-1.6	-1.3	-1.1	-1.2	-1.8	-0.4	-0.7	-1.4	-0.9	-1.8	-0.8	-0.2	-0.9	-0.5	-2.0	-1.4	-1.6	-1.4	-1.5	-1.9	-1.6	-0.9
Arm predicted mass (right)	1.4	7.3	15.2	-2.8	-2.9	-3.6	-2.9	-2.7	-1.9	-2.6	-3.2	-3.9	-1.0	-2.3	-1.6	-3.1	-2.3	-1.9	-1.7	-1.9	-2.6	-2.8	-3.0	-2.6	-2.7	-2.8	-3.2	-3.5
Deep venous thrombosis (DVT) (self-reported)	1.4	1.9	4.2	-1.4	-1.4	-1.2	-1.7	-1.3	-1.0	-1.3	-1.7	-0.3	-0.7	-1.4	-0.9	-1.9	-0.9	-0.2	-1.1	-0.6	-2.0	-1.5	-1.7	-1.5	-1.6	-2.0	-1.7	-0.9
Prostate Cancer	1.3	1.8	4.6	1.0	1.1	0.3	1.8	1.7	2.0	1.4	2.1	-0.5	-0.6	1.7	-0.1	1.7	1.1	1.7	1.6	1.1	1.2	1.3	1.2	1.0	0.9	0.5	1.8	1.2
Lupus	1.3	2.0	4.5	-1.1	-1.1	-1.4	-1.6	-1.1	-1.4	-1.5	-1.2	-1.7	-0.6	-1.8	-0.9	-1.9	-1.0	-1.3	-2.1	-1.5	-1.4	-1.5	-1.5	-1.5	-1.6	-1.1	-1.6	-1.1
Ulcerative Colitis	1.3	1.9	5.8	-1.6	-1.7	-1.5	-1.1	-1.7	-1.3	-1.3	-0.9	-0.3	-1.2	-1.5	-1.4	-1.1	-1.4	-1.4	-1.2	-1.9	-1.1	-1.3	-1.4	-1.3	-1.7	-0.2	-1.3	-2.4
Medication for hormone replacement therapy	1.3	1.4	6.5	-1.0	-0.9	-0.3	-1.7	-1.0	-1.0	-1.6	-1.2	-2.5	-0.2	-1.2	-0.5	-1.4	-0.7	-0.8	-1.7	-1.1	-0.4	-1.1	-1.1	-1.0	-1.1	-0.1	-1.3	-1.5
Impedance of leg (right)	1.3	6.4	10.0	2.8	2.8	2.5	2.5	2.6	2.0	2.5	2.8	1.6	1.4	2.6	2.1	3.1	2.4	1.7	1.3	2.2	3.1	2.9	3.1	2.8	3.0	1.9	3.2	3.0
Time employed in main current job	1.3	1.5	2.5	1.2	1.2	0.5	1.3	1.2	1.5	1.1	1.2	-1.3	0.8	1.5	1.0	1.3	1.3	1.4	0.4	1.3	1.6	1.3	1.2	1.3	1.3	-0.2	1.3	1.5
Length of working week for main job	1.3	1.5	4.4	0.8	0.8	1.5	0.7	1.2	1.8	0.8	1.7	1.6	2.1	0.8	2.0	0.5	1.6	1.4	1.3	1.6	-0.4	1.0	0.5	1.3	1.1	0.4	0.5	0.1
Migraine (self-reported)	1.3	1.6	2.7	1.3	1.3	1.0	1.7	1.4	1.3	1.4	1.6	-0.8	-0.2	1.7	0.1	1.5	1.2	1.6	0.8	1.0	1.0	1.3	1.4	0.9	1.0	1.6	1.5	1.0
Suffer from ‘nerves’	1.3	2.0	3.8	1.3	1.4	1.7	1.6	1.7	1.8	1.8	1.5	1.6	0.2	1.8	0.6	1.8	1.1	1.2	1.9	1.1	0.7	1.2	1.4	1.4	1.5	0.2	1.5	1.6
Ever had stillbirth, spontaneous miscarriage or termination	1.3	1.4	2.8	-1.6	-1.5	-0.9	-1.7	-1.3	-1.0	-1.6	-0.6	0.4	0.1	-1.5	-0.3	-1.6	-0.9	-0.6	-0.6	-0.7	-1.2	-1.2	-1.6	-0.8	-1.4	-1.3	-1.5	-1.4
Pain experienced in last month	1.3	2.2	4.1	1.3	1.4	2.0	1.8	1.6	1.7	1.5	1.9	0.6	0.2	1.3	0.4	1.6	1.4	1.2	1.7	0.9	1.5	1.7	1.5	1.4	1.1	1.4	1.9	1.9
Coronary Artery Disease (CAD)	1.2	1.5	6.2	-1.5	-1.5	-2.5	-0.8	-1.2	-0.6	-0.9	-1.3	0.3	-0.5	-1.5	-0.6	-1.1	-0.9	-0.3	0.2	-0.1	-1.4	-1.3	-1.6	-1.2	-1.3	-1.4	-1.4	-1.4
Systolic Blood Pressure	1.2	6.0	8.5	-2.8	-2.9	-2.8	-1.9	-2.7	-1.8	-2.2	-2.2	2.5	-2.4	-2.9	-2.9	-1.9	-2.4	-2.1	-1.4	-2.7	-2.5	-2.5	-2.5	-2.4	-2.8	-2.8	-2.1	-2.2
Systolic blood pressure, automated reading	1.2	3.6	6.6	-2.1	-2.1	-2.2	-1.4	-2.1	-1.8	-2.1	-1.5	2.6	-1.3	-2.4	-1.6	-1.8	-1.7	-1.5	-2.0	-1.9	-1.6	-1.9	-2.0	-1.8	-2.1	-1.9	-1.8	-1.8
Supplements: Zinc	1.2	1.3	2.7	-1.3	-1.3	-1.3	-0.6	-1.1	-0.6	-0.6	-1.0	0.3	-1.5	-1.6	-1.6	-0.9	-1.4	-0.1	0.5	-0.9	-1.6	-1.3	-1.4	-1.5	-1.6	0.3	-1.0	-0.5
Medication: Ventolin 100micrograms inhaler	1.2	1.6	7.1	0.9	1.0	1.8	1.3	1.2	1.6	0.8	1.3	0.2	1.8	0.9	1.8	0.8	1.1	1.2	2.7	1.7	0.9	1.0	0.8	1.4	1.2	-0.0	0.6	0.1
Reaction Time	1.1	2.1	5.6	-1.2	-1.2	-1.7	-1.8	-0.8	-0.5	-2.1	-1.9	-1.5	-0.4	-2.4	-0.8	-1.9	-1.4	0.1	-1.8	-0.3	-1.1	-1.6	-1.8	-1.8	-1.6	-1.0	-1.8	-0.7
Type 2 Diabetes (T2D) (2012)	1.1	1.3	3.1	1.0	1.1	0.1	1.0	1.2	1.2	1.0	0.7	-0.0	0.8	1.4	0.7	1.2	1.1	1.4	0.6	1.6	1.6	1.2	1.0	0.6	1.1	1.8	1.1	1.4
Blood Platelet Count	1.1	12.2	21.9	-4.4	-4.5	-3.7	-4.3	-4.2	-3.1	-4.0	-4.3	-0.6	0.1	-4.1	-0.8	-4.3	-2.6	-1.4	-1.9	-1.7	-3.9	-4.0	-4.6	-2.7	-3.6	-3.7	-4.7	-3.0
Current tobacco smoking	1.1	1.8	3.7	1.4	1.2	1.0	0.9	1.3	1.3	1.9	1.3	1.3	1.6	1.8	1.5	1.7	1.6	1.2	1.3	1.4	0.5	1.3	1.3	1.6	1.6	-0.6	1.4	0.8
Impedance of leg (left)	1.1	5.5	9.1	2.6	2.7	2.3	2.3	2.5	1.8	2.3	2.7	1.2	1.1	2.3	1.6	2.9	2.0	2.0	1.1	2.1	2.8	2.6	2.9	2.5	2.6	1.8	3.0	3.0
Number of live births	1.1	1.6	4.3	1.4	1.5	0.5	1.3	1.8	2.0	1.1	1.7	0.3	0.8	0.7	0.8	0.6	1.1	2.1	1.9	1.8	1.4	1.0	0.8	0.8	0.9	-1.3	0.7	0.9
Hypothyroidism/myxoedema (self-reported)	1.1	2.2	6.9	1.3	1.3	0.6	0.6	1.6	2.0	0.8	0.9	-2.2	2.6	1.3	2.6	0.3	1.7	2.0	0.7	2.2	1.4	1.2	0.8	2.0	1.3	0.1	0.5	-0.0
Medication: Seretide 50 evohaler	1.1	1.3	3.8	-0.9	-0.9	-0.3	-1.5	-1.4	-1.9	-1.0	-1.1	-0.2	-0.2	-1.0	-0.6	-1.3	-1.4	-1.7	-1.3	-1.5	-0.9	-1.2	-0.9	-1.2	-1.0	-0.5	-1.2	-1.2
Overall health rating	1.1	2.3	4.1	-1.7	-1.7	-1.2	-1.5	-1.7	-1.6	-1.6	-1.9	-0.5	-1.7	-1.2	-2.0	-1.1	-2.0	-1.3	-0.9	-1.6	-1.8	-1.9	-1.6	-1.8	-1.7	-0.5	-1.4	-1.1
Basal cell carcinoma (self-reported)	1.1	1.3	3.0	0.8	0.8	1.7	1.0	1.2	1.4	0.6	1.6	1.2	1.6	1.3	1.6	0.9	1.6	1.4	0.9	1.1	0.1	1.3	0.6	1.4	0.9	0.2	1.0	0.5
BMI	1.0	6.0	18.2	-2.5	-2.5	-2.4	-3.2	-2.4	-2.0	-3.1	-2.8	-4.3	-0.0	-2.0	-0.7	-3.2	-1.6	-1.1	-2.6	-1.2	-2.4	-2.5	-2.7	-2.2	-2.5	-1.1	-3.1	-2.6
Alcohol usually taken with meals	1.0	1.7	3.3	-1.7	-1.8	-1.5	-0.9	-1.6	-1.2	-1.1	-1.0	-0.6	-1.4	-0.7	-1.6	-0.9	-0.9	-1.4	-0.7	-1.8	-1.3	-1.2	-1.4	-1.4	-1.6	1.4	-1.0	-1.0
Hayfever/allergic rhinitis (self-reported)	1.0	1.4	3.9	1.3	1.3	0.7	1.6	1.2	1.0	1.4	1.1	0.5	-0.3	1.1	0.1	1.6	0.9	1.1	0.5	0.5	1.6	1.3	1.4	1.0	0.9	0.8	1.7	2.0
Lung cancer (father)	1.0	1.2	3.1	1.6	1.6	0.7	1.5	1.8	1.5	1.0	1.4	0.1	0.0	1.1	0.2	1.2	0.9	0.6	0.1	0.4	1.1	1.3	1.3	0.6	1.0	1.4	1.3	0.8
Tense / ‘highly strung’	1.0	1.7	3.8	1.5	1.5	1.4	1.5	1.1	0.7	1.9	1.5	1.9	0.0	1.6	0.5	1.6	0.8	-0.4	1.7	0.3	1.2	1.5	1.8	1.1	1.7	0.5	1.7	0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.6	6.5	1.2	1.1	1.4	0.3	1.0	0.9	1.2	0.7	0.4	2.4	1.1	2.5	0.8	1.9	0.6	0.9	1.3	0.7	1.1	1.0	1.9	1.7	-0.7	0.6	0.4
Gout (self-reported)	1.0	1.3	3.5	-0.9	-1.1	-1.1	-0.7	-1.2	-1.6	-1.3	-1.9	0.2	-0.6	-1.4	-0.9	-1.2	-1.4	-1.7	-1.5	-1.4	-0.4	-1.0	-1.0	-1.4	-1.0	0.4	-1.0	-0.2
Number of children fathered	1.0	1.1	2.8	1.2	1.1	1.0	1.2	0.6	0.1	1.5	0.9	-0.4	0.9	1.7	0.9	0.8	1.6	0.3	1.1	0.7	1.2	1.1	1.5	1.1	1.3	1.0	0.9	0.9
Chest pain or discomfort	1.0	1.4	6.6	-1.1	-1.1	-1.0	-1.4	-1.1	-1.1	-1.0	-0.8	-0.4	-0.2	-1.9	-0.5	-1.5	-0.8	-0.1	-1.1	-0.9	-1.1	-1.3	-1.4	-0.8	-1.4	-2.6	-1.4	-0.6
Miserableness	1.0	1.7	6.1	-1.2	-1.2	-0.9	-2.5	-0.8	-0.6	-1.8	-1.3	-0.0	0.7	-1.4	0.4	-1.6	-0.2	-0.7	-1.7	-0.3	-2.4	-1.3	-1.6	-0.7	-0.9	-1.4	-1.6	-1.4
Medication: Atorvastatin	1.0	1.3	2.7	-1.3	-1.2	-1.6	-1.6	-0.9	-0.6	-1.3	-1.6	-0.7	-0.3	-0.8	-0.4	-1.3	-0.7	-0.2	-1.5	-0.3	-1.0	-1.5	-1.4	-1.1	-1.1	-0.9	-1.5	-1.0
Height	0.9	17.0	36.0	-4.5	-4.7	-6.0	-4.0	-4.5	-4.1	-3.6	-4.6	-1.0	-3.0	-4.2	-3.6	-4.1	-4.3	-4.2	-3.3	-4.4	-3.8	-4.4	-4.4	-4.1	-4.5	-2.7	-4.2	-4.5
Neuroticism	0.9	2.1	4.2	1.5	1.5	1.1	1.0	1.6	1.2	1.6	2.0	2.0	1.2	1.9	1.5	1.8	1.6	0.6	1.0	0.9	0.6	1.5	1.6	1.9	1.7	0.5	1.6	0.8
Frequency of depressed mood in last 2 weeks	0.9	1.3	6.8	0.7	0.7	1.3	0.9	0.7	0.7	1.2	1.1	2.6	0.5	1.3	0.7	1.6	0.6	0.4	1.9	0.5	-0.0	0.8	0.9	1.3	1.1	-1.5	1.1	1.0
Hearing difficulty/problems: Yes	0.9	1.4	3.5	-1.1	-1.2	-1.5	-0.3	-1.4	-1.1	-0.5	-0.4	0.9	-1.7	-1.1	-1.7	-0.8	-1.3	-1.6	0.8	-1.5	-0.7	-1.1	-1.0	-1.4	-1.3	0.0	-0.9	-1.9
Vitamin and mineral supplements	0.9	1.3	4.2	1.3	1.2	1.1	0.3	1.5	1.7	0.6	0.7	-1.0	0.9	0.7	1.2	0.3	0.9	1.8	-0.4	2.0	1.1	1.1	1.1	1.1	1.2	1.3	0.8	0.5
Hearing difficulty/problems with background noise	0.9	1.5	4.0	-1.2	-1.3	-1.7	-0.3	-1.4	-1.3	-0.6	-0.4	0.8	-1.6	-0.9	-1.6	-0.4	-1.4	-1.7	0.2	-2.0	-1.3	-0.9	-0.9	-1.0	-1.3	0.9	-0.5	-1.9
Had menopause	0.9	1.1	7.2	-0.2	-0.1	-0.2	-0.8	-0.5	-1.2	-1.4	-0.5	-2.7	-0.8	-0.7	-0.7	-0.5	-0.4	-0.7	-2.6	-0.5	0.3	-0.6	-0.1	-0.9	-0.4	1.8	-0.5	-0.8
Illnesses of siblings	0.9	1.2	2.4	1.3	1.3	0.9	1.1	1.4	1.2	1.3	1.6	1.2	0.3	1.2	0.7	1.0	1.1	1.0	0.7	0.6	1.0	1.3	1.1	1.1	0.8	0.4	1.4	1.5
Medication: Lansoprazole	0.9	1.1	3.3	-1.1	-1.2	-0.1	-1.4	-1.1	-0.6	-0.7	-0.8	-1.4	0.5	-0.9	-0.0	-1.2	-0.8	-0.4	-1.0	-0.5	-1.8	-1.1	-1.2	-0.5	-1.0	-1.8	-1.4	-1.0
Breast cancer (self-reported)	0.9	1.1	4.2	0.9	1.0	1.0	0.7	1.1	1.2	1.1	1.2	0.3	0.6	1.4	0.6	1.1	0.8	0.2	0.5	0.8	2.1	1.1	1.2	1.2	1.2	0.4	1.2	0.5
Tinnitus: Yes, now most or all of the time	0.9	1.1	3.1	-0.9	-0.9	-0.7	-0.7	-1.1	-1.0	-0.7	-0.6	-1.0	-0.9	-0.6	-1.1	-0.9	-1.5	-1.4	-0.3	-1.4	-1.6	-1.1	-0.8	-1.1	-1.0	-0.7	-1.0	-1.8
Diastolic blood pressure, automated reading	0.9	2.9	6.3	-1.8	-1.8	-2.2	-1.2	-1.8	-2.0	-1.8	-1.2	1.6	-2.2	-1.0	-2.2	-0.9	-1.9	-1.7	-2.5	-2.0	-1.0	-1.6	-1.4	-1.9	-1.8	-0.3	-1.1	-1.6
Myopia	0.9	1.3	5.2	-1.1	-0.9	-0.4	-1.3	-0.5	-0.5	-1.8	-0.4	2.3	-0.8	-1.6	-0.8	-1.3	-1.1	0.5	-1.9	-0.3	-1.4	-1.1	-1.3	-0.8	-1.4	0.6	-1.2	-0.9
Multivitamins +/- minerals	0.8	1.0	2.9	-1.2	-1.1	-0.8	-0.3	-1.4	-1.3	-0.7	-0.5	1.2	-0.4	-0.7	-0.7	-0.5	-0.6	-1.7	0.2	-1.5	-0.8	-0.9	-1.1	-0.8	-1.0	-1.2	-0.8	-1.1
Nervous feelings	0.8	1.5	6.4	1.0	1.1	1.1	1.2	1.3	1.2	1.4	1.2	2.5	0.3	1.2	0.6	1.7	0.7	0.3	1.8	0.7	0.5	0.9	1.4	1.1	1.5	0.8	1.3	1.3
Had other major operations	0.8	1.0	2.4	1.4	1.3	1.1	0.6	1.1	0.7	1.2	0.7	0.5	1.3	1.4	1.3	0.6	1.3	-0.4	0.4	0.0	1.6	0.9	1.2	1.1	1.1	-0.2	0.6	0.6
Shortness of breath walking on level ground	0.8	0.9	4.2	-0.6	-0.8	-2.0	-0.7	-0.9	-0.8	-0.2	-0.9	-1.7	-0.6	-0.5	-0.8	-0.7	-0.8	-0.9	-0.5	-1.2	-0.3	-1.1	-0.8	-1.0	-0.9	-0.2	-1.0	-1.3
Medication: Ibuprofen	0.8	1.0	3.0	0.9	1.0	1.5	0.7	1.2	1.0	0.4	1.0	-0.1	0.2	1.3	0.6	0.9	0.9	1.7	0.0	1.4	0.8	0.9	0.8	0.6	0.8	1.2	0.9	1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	1.0	2.6	-1.0	-1.0	-0.3	-0.8	-1.4	-1.6	-0.6	-1.1	-1.4	-0.7	-0.7	-1.0	-0.9	-1.2	-0.9	-0.4	-1.1	-0.9	-1.0	-0.9	-0.9	-1.1	-0.2	-1.0	-1.0
Handedness (chirality/laterality): Left-handed	0.8	1.0	3.9	0.3	0.2	2.0	0.5	0.7	1.4	0.5	0.7	1.2	1.2	0.6	1.2	0.5	1.5	1.0	1.6	1.0	0.4	1.0	0.4	1.1	0.8	1.0	0.6	0.7
Smoking status: Current	0.8	1.2	2.6	1.0	0.8	0.9	0.6	0.8	0.8	1.6	0.9	1.3	1.5	1.6	1.4	1.4	1.3	0.7	1.2	1.0	0.4	0.9	0.9	1.3	1.2	-1.2	1.0	0.5
Medication: Paracetamol	0.8	1.2	3.3	1.3	1.4	0.9	1.1	1.6	1.1	0.5	1.1	0.5	0.3	1.6	0.5	1.3	0.8	1.4	-0.3	1.1	1.1	1.1	1.2	0.8	1.1	0.9	1.3	1.8
Illnesses of father: High blood pressure	0.8	1.0	3.1	-1.0	-1.1	-1.8	0.2	-1.2	-0.9	0.1	-0.4	0.7	-1.4	-0.9	-1.3	-0.1	-1.5	-1.2	0.7	-1.4	-1.1	-0.9	-0.9	-1.0	-1.0	0.2	-0.5	-0.9
Ever depressed for a whole week	0.8	1.0	2.9	0.9	0.8	0.1	0.4	0.6	0.6	1.5	0.1	-0.8	1.5	1.4	1.6	1.0	1.0	1.2	0.7	1.1	0.8	0.8	0.8	1.7	1.0	-0.5	0.8	1.5
Supplements: Calcium	0.8	0.8	5.1	-0.1	0.1	0.8	0.3	-0.5	-1.1	0.4	0.1	1.1	-2.2	0.2	-1.8	0.3	-1.2	-1.1	-0.0	-1.6	-0.6	-0.3	0.2	-0.9	-0.7	1.1	0.4	0.7
Impedance of whole body	0.8	4.2	8.5	2.1	2.3	2.5	1.9	2.2	1.6	2.0	2.5	2.5	0.7	2.0	1.2	2.6	1.6	1.8	1.1	1.6	2.2	2.1	2.4	2.1	2.1	1.4	2.6	2.9
Alzheimer’s Disease (in father)	0.7	0.8	1.6	1.0	1.0	1.0	0.9	0.9	0.6	0.5	0.9	0.4	0.4	1.2	0.7	0.9	1.1	1.3	-0.0	1.2	0.9	1.2	1.0	0.8	0.9	0.8	1.1	0.5
Body Mass Index (BMI) (2010)	0.7	0.9	4.2	0.6	0.7	0.8	1.4	0.9	1.4	1.2	1.0	-1.1	-0.1	1.1	0.1	1.3	0.4	0.8	2.0	0.9	0.8	0.7	0.7	0.6	0.7	0.7	0.9	0.1
Respiratory disease	0.7	1.4	7.0	0.7	0.8	1.3	2.0	1.0	1.6	1.2	1.7	0.3	0.4	1.0	0.6	1.3	1.0	1.5	2.6	1.1	1.0	1.1	0.7	1.1	0.8	-0.1	1.2	0.9
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	1.9	-1.2	-1.1	-0.4	-1.1	-0.8	-0.1	-0.7	-0.7	-0.1	-0.2	-1.2	-0.4	-1.0	-0.9	-0.8	0.7	-0.8	-0.9	-1.1	-1.3	-0.5	-1.1	-1.4	-1.1	-0.9
High blood pressure (mother)	0.7	1.0	3.6	-1.1	-1.1	-1.8	-0.9	-0.7	-0.0	-0.4	0.3	1.9	-1.4	-0.8	-1.6	-0.5	-1.0	-0.0	-0.7	-0.5	-1.2	-0.6	-0.9	-1.1	-1.1	0.4	-0.3	-0.7
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	4.1	1.0	1.1	1.3	0.5	1.1	0.8	0.5	1.1	0.2	0.4	1.3	0.7	0.8	0.6	1.6	0.3	1.3	0.5	0.8	0.7	0.5	0.9	0.1	0.9	2.0
Exposure to tobacco smoke outside home	0.7	0.9	2.2	0.9	1.1	1.2	0.3	0.9	0.9	0.9	1.5	0.5	-0.3	1.1	-0.3	1.1	0.5	1.3	-0.3	1.1	1.2	0.8	1.1	0.4	0.8	0.5	1.2	1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	1.0	3.6	0.9	0.9	1.9	0.8	0.6	0.5	1.0	0.7	-0.5	0.8	0.9	0.9	1.2	0.9	1.0	1.1	1.2	0.4	1.1	1.0	1.3	1.2	0.3	1.1	1.1
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	3.3	-1.4	-1.2	0.2	-1.1	-0.8	-0.2	-1.5	-1.1	-1.4	-0.3	-1.3	-0.3	-1.3	-1.1	0.2	-0.5	-0.1	-1.8	-1.2	-1.4	-0.7	-1.1	-0.6	-1.4	-0.6
High cholesterol (Self-reported)	0.7	1.3	2.9	-1.0	-1.0	-1.7	-1.6	-0.6	-0.5	-1.3	-1.0	0.3	-0.6	-1.4	-0.7	-1.4	-1.3	0.1	-1.7	-0.6	-0.8	-1.5	-1.4	-1.1	-1.4	-0.9	-1.4	-1.1
Heart disease (siblings)	0.7	0.9	3.0	1.3	1.2	1.3	0.8	0.7	-0.1	0.2	-0.2	-0.8	1.7	0.4	1.6	0.2	0.6	0.7	0.3	1.3	0.9	0.9	1.1	0.9	1.3	0.0	0.4	1.2
Depressed Affect (Nagel 2018)	0.6	1.2	3.8	0.8	0.9	1.6	-0.6	1.1	1.0	0.2	0.9	0.4	2.0	0.8	1.9	0.4	1.3	1.3	-0.0	1.9	-0.5	0.6	0.5	1.2	1.2	-1.5	0.3	0.5
Breast Cancer	0.6	1.4	4.8	1.4	1.4	-0.3	1.8	1.3	0.8	2.2	1.3	1.0	-0.8	1.3	-0.5	1.6	0.6	0.1	1.2	-0.2	1.4	0.9	1.3	0.5	0.9	0.0	1.5	1.6
HDL Cholesterol	0.6	1.0	3.7	1.1	1.3	1.9	0.4	0.9	0.3	0.8	1.2	0.5	0.9	1.1	0.9	1.0	0.8	0.8	0.0	0.9	0.7	0.9	1.2	0.9	1.1	0.8	1.0	1.9
Smoking Status	0.6	1.5	3.2	1.3	1.1	0.9	0.8	0.8	0.5	1.5	0.9	-0.8	1.8	1.3	1.6	1.3	1.5	1.3	0.2	1.4	1.6	1.3	0.9	1.7	1.2	-1.6	1.2	0.8
Number of treatments/medications taken	0.6	1.1	2.7	-1.2	-1.2	-0.7	-1.2	-0.8	-0.5	-1.4	-0.8	-0.4	0.1	-1.1	-0.2	-1.4	-1.1	-0.3	-1.0	-0.8	-1.2	-1.5	-1.5	-0.9	-1.3	-0.5	-1.6	-1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	3.2	0.5	0.5	1.4	0.2	0.4	0.5	0.8	0.8	1.2	0.8	0.6	0.8	1.0	0.5	0.7	1.7	0.9	-0.0	0.8	0.6	1.2	0.9	-1.8	0.8	1.0
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	1.7	-1.1	-1.2	-0.6	-0.7	-1.1	-0.4	-1.0	-1.1	0.1	-0.2	-0.9	-0.3	-1.1	-0.8	-0.6	0.1	-0.7	-0.9	-0.8	-1.1	-0.8	-1.0	0.6	-1.2	-1.3
Financial difficulties in last 2 years	0.6	0.7	1.6	-1.0	-0.9	-0.2	-1.2	-1.3	-1.2	-1.2	-0.5	0.5	0.1	-0.9	-0.1	-1.2	-0.3	-0.4	-0.0	-0.3	-1.0	-1.0	-1.0	-0.6	-0.8	-0.6	-1.3	-1.1
Diabetes (self-reported)	0.6	0.9	2.7	-1.1	-1.1	-0.4	-0.8	-0.7	-0.3	-0.9	-0.5	0.6	-1.0	-0.9	-1.2	-1.2	-1.6	-0.4	-0.1	-0.9	-0.9	-1.2	-1.2	-1.1	-1.4	-0.4	-1.1	-0.7
Impedance of arm (right)	0.6	2.7	8.1	1.5	1.7	2.6	1.5	1.7	1.3	1.4	2.1	2.8	0.5	1.2	1.0	2.0	1.0	1.5	1.1	1.2	1.4	1.5	1.7	1.7	1.5	0.9	1.9	2.3
Falls in the last year	0.6	0.8	2.4	-1.0	-1.2	-0.1	-0.4	-1.5	-1.4	-1.0	-1.2	0.2	-0.0	-0.6	-0.3	-0.7	-1.0	-0.9	0.2	-0.1	-1.5	-0.5	-0.8	-0.6	-0.4	-0.8	-0.8	-1.4
Mouth/teeth dental problems: Dentures	0.6	0.9	5.2	0.7	0.8	1.1	0.8	1.5	1.8	0.5	0.7	-0.7	0.4	0.4	0.5	0.5	1.0	2.3	0.9	1.5	0.0	0.4	0.3	0.6	0.4	-1.3	0.3	0.7
Glaucoma (self-reported)	0.6	0.7	3.6	0.8	0.8	0.4	0.4	1.0	1.1	0.5	0.7	-0.2	1.9	0.5	1.6	0.1	1.6	0.0	0.7	0.3	1.2	0.6	0.5	1.2	0.8	-0.6	0.0	0.2
Birth weight	0.6	1.3	6.0	-1.1	-1.1	-1.6	-1.0	-1.1	-1.1	-1.2	-1.9	-2.1	0.3	-0.6	-0.0	-0.7	-1.1	-0.8	-0.1	-0.5	-0.6	-1.0	-1.0	-0.4	-0.8	-2.5	-1.0	-1.2
Commuting to job workplace: Walk	0.6	0.7	4.4	0.2	0.1	-0.4	-0.1	-0.5	-1.4	-0.0	-0.8	1.3	-0.9	-0.1	-0.6	-0.2	-0.7	-2.1	-0.8	-2.0	0.1	-0.2	0.2	-0.3	-0.2	-0.7	-0.0	-0.8
Supplements: Fish oil (including cod liver oil)	0.6	0.8	1.8	1.1	1.2	1.3	0.7	0.9	0.5	1.0	0.7	-0.0	1.2	1.1	1.1	1.0	1.1	0.2	0.1	0.9	1.0	0.8	1.1	0.8	1.3	0.5	0.7	1.1
Number of operations (self-reported)	0.6	0.9	2.0	1.4	1.3	1.3	0.3	1.3	0.7	0.5	0.5	-1.4	1.0	1.1	1.1	0.5	1.3	0.4	-0.6	0.5	1.2	0.7	1.1	0.8	1.1	0.5	0.5	0.8
Major Depression (MDD)	0.5	0.6	8.4	-0.5	-0.4	-1.2	-0.5	-0.3	-0.1	-0.6	-0.6	-2.9	0.4	-0.4	0.1	-0.4	-0.6	-0.2	-0.6	0.0	0.2	-0.1	-0.5	-0.0	-0.4	0.6	-0.3	-0.7
Age at First Birth	0.5	0.7	2.2	0.4	0.5	0.6	1.2	-0.2	-0.7	0.8	0.7	1.0	-1.0	1.2	-0.7	0.9	-0.3	-0.6	-0.3	-0.5	1.1	0.6	1.0	0.2	0.5	1.4	1.1	1.5
Neuroticism (2016)	0.5	0.8	3.6	0.2	0.2	0.6	0.2	0.6	0.9	0.6	0.7	1.9	1.5	0.6	1.4	0.6	0.8	0.9	1.6	1.3	-0.5	0.6	0.1	1.1	0.7	-0.5	0.3	0.4
Sensitivity / hurt feelings	0.5	0.8	2.5	-1.2	-1.2	-1.1	-1.0	-0.9	-0.5	-1.4	-0.9	0.7	-0.3	-0.8	-0.2	-0.7	-0.8	-0.6	-0.8	-0.5	-1.6	-0.9	-1.1	-0.7	-0.7	-0.2	-0.9	-1.1
Average weekly fortified wine intake	0.5	0.5	1.9	-0.8	-0.8	-1.1	0.0	-0.8	-0.6	0.1	-0.7	0.8	-1.2	-0.5	-0.9	-0.1	-0.8	-1.4	0.5	-1.2	-0.1	-0.8	-0.4	-0.7	-0.5	0.1	-0.4	0.1
Medication: Levothyroxine sodium	0.5	0.8	4.3	0.7	0.6	-0.7	-0.1	0.9	1.2	-0.1	-0.1	-2.1	1.9	0.3	1.9	-0.4	0.9	0.7	-0.4	1.0	1.1	0.5	0.2	1.1	0.6	-0.1	-0.2	-0.6
Mouth/teeth dental problems	0.5	0.7	2.5	-0.2	-0.2	-1.2	-0.2	-0.5	-1.1	-0.4	-0.0	1.5	-1.6	-0.7	-1.4	-0.3	-0.7	-1.5	-0.6	-1.2	0.5	-0.4	-0.1	-1.3	-0.5	1.0	-0.0	0.0
Allergy	0.5	1.1	3.4	-1.0	-0.9	-1.6	-1.2	-0.2	0.3	-1.4	-1.0	0.9	0.1	-1.8	-0.4	-1.7	-0.3	-0.2	-1.2	-0.2	-1.0	-1.1	-1.3	-1.1	-1.0	-0.5	-1.6	-1.2
Alcohol intake versus 10 years previously	0.5	0.7	8.9	0.5	0.6	1.1	-0.3	0.7	0.8	-0.2	0.2	-3.0	1.2	0.2	1.0	-0.6	0.3	0.8	0.4	0.9	-0.1	0.1	0.0	0.4	0.3	-1.2	-0.4	-0.0
Noisy workplace	0.5	0.6	1.4	-0.5	-0.8	-0.5	-1.2	-0.6	-0.6	-0.2	-0.8	0.2	-0.5	-0.9	-0.7	-1.0	-0.4	-0.9	-0.8	-1.0	-0.4	-0.8	-0.7	-0.8	-0.8	-1.1	-0.8	-0.7
Impedance of arm (left)	0.5	2.5	10.1	1.3	1.5	2.0	1.4	1.6	1.2	1.4	1.8	3.2	0.3	1.4	0.7	2.1	0.8	1.5	0.9	1.0	1.3	1.5	1.6	1.7	1.4	0.7	2.0	2.3
Birth weight of first child	0.5	0.9	3.1	-0.8	-0.7	-1.8	-0.8	-0.9	-1.1	-1.1	-0.7	-1.3	-1.4	-0.8	-1.0	-0.5	-1.6	-0.2	-1.3	-0.1	-1.0	-0.7	-0.7	-0.8	-0.7	-0.0	-0.5	-0.3
Medication: Paracetamol	0.5	0.8	4.2	0.9	1.1	0.5	0.5	1.3	0.9	-0.0	0.8	0.6	0.3	1.2	0.5	0.8	0.5	1.6	-0.9	1.2	0.5	0.7	0.8	0.5	0.8	0.6	0.9	2.0
Chronic bronchitis/emphysema (mother)	0.5	0.6	1.9	0.8	0.7	0.6	0.3	0.7	0.5	0.5	0.8	-0.4	1.4	0.7	1.3	0.6	1.0	1.1	0.1	1.1	0.3	0.7	0.7	1.0	0.7	0.4	0.6	0.7
Osteoarthritis (self-reported)	0.5	0.6	3.6	-0.2	-0.4	0.4	-0.6	-0.6	-0.9	-1.1	-0.9	-1.5	-0.1	-0.5	-0.2	-0.6	-0.1	-0.8	-1.2	-0.4	-0.9	-0.3	-0.3	-0.8	-0.3	1.9	-0.5	-0.9
Mother’s age at death	0.5	0.7	2.7	0.4	0.4	-1.6	0.5	0.4	-0.1	0.2	-0.4	0.3	-1.6	0.5	-1.5	0.5	-0.2	-1.1	-0.8	-1.6	0.9	0.1	0.7	-0.5	-0.1	0.4	0.6	0.8
Financial situation satisfaction	0.5	0.6	3.6	-0.1	-0.1	0.8	-0.8	0.1	0.5	-0.6	0.3	-0.7	1.9	0.3	1.4	-0.3	0.1	1.6	0.5	1.4	-0.7	0.1	-0.3	0.8	0.2	-1.0	-0.4	-0.2
Commuting to job workplace: Public transport	0.5	0.6	5.5	0.1	0.2	-0.6	-0.1	-0.2	-1.0	-0.4	-0.4	-0.1	-1.4	0.2	-1.2	0.2	-0.9	-0.5	-2.3	-1.3	0.8	-0.1	0.2	-0.4	-0.5	0.2	0.3	0.5
Medication: Bendroflumethiazide	0.5	0.8	2.6	-0.7	-0.8	-0.9	-0.9	-0.8	-0.8	-0.7	-1.0	-0.9	-0.8	-0.5	-0.8	-1.1	-0.8	0.3	-1.6	-0.6	-0.8	-1.2	-0.8	-0.8	-1.1	-0.2	-1.1	0.4
Ever smoked	0.5	0.9	3.6	0.9	0.8	0.6	0.5	0.8	0.6	0.8	0.8	0.9	1.9	0.6	1.8	0.3	1.3	1.1	0.4	0.8	0.4	0.6	0.4	1.3	0.7	-1.7	0.1	0.6
Irritable Bowel Disease (IBD)	0.4	1.0	4.5	0.7	0.5	0.2	0.7	0.9	1.4	0.4	0.7	0.1	2.1	0.2	1.9	0.1	1.6	0.6	1.1	1.0	0.7	0.9	0.1	1.1	0.7	-1.9	0.1	-0.6
Ulcerative Colitis (UC)	0.4	0.8	3.7	-0.8	-0.9	-0.7	-0.4	-0.6	0.0	-1.1	-0.1	0.7	-0.1	-1.6	-0.4	-1.3	-0.4	-0.1	-0.3	-0.7	-0.7	-0.7	-1.4	-0.9	-1.3	-0.7	-1.1	-1.9
Fasting Glucose	0.4	0.5	2.5	-0.0	0.1	0.9	0.9	0.6	1.2	0.7	1.1	0.3	0.3	0.9	0.4	0.8	0.5	0.5	1.6	0.4	0.0	0.6	0.3	0.6	0.6	-0.0	0.6	0.5
HbA1C	0.4	0.4	1.3	-0.1	-0.3	-0.7	0.8	-0.1	-0.1	0.2	0.2	-1.1	0.4	0.6	0.7	0.8	0.8	0.2	0.6	0.3	0.6	0.9	0.6	0.9	0.7	-0.2	0.9	1.0
Ever used hormone-replacement therapy (HRT)	0.4	0.5	4.8	0.5	0.7	0.6	0.2	0.5	0.2	0.2	1.0	-0.6	-1.2	0.3	-0.9	0.4	-0.4	-0.1	-0.9	-0.6	1.2	0.1	0.6	-0.4	0.1	2.2	0.4	-0.0
Taking other prescription medications	0.4	0.6	2.1	0.8	0.9	0.8	0.5	0.9	0.8	0.6	1.1	-0.4	0.8	0.7	0.8	0.3	0.8	1.5	0.2	0.9	0.6	0.4	0.3	0.7	0.4	-0.9	0.3	0.7
Supplements: Glucosamine	0.4	0.6	2.6	-0.5	-0.7	-0.9	-0.1	-1.0	-1.4	-0.7	-1.6	0.0	0.1	-0.7	0.0	-0.4	-0.8	-1.2	-0.8	-0.7	-0.7	-0.3	-0.4	-0.5	-0.3	1.2	-0.5	-0.4
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	2.1	0.1	-0.1	0.3	-0.3	-0.1	0.0	0.5	-0.5	-1.3	1.3	0.5	1.1	-0.0	0.2	1.1	0.4	0.9	-0.1	0.1	-0.1	1.0	0.3	-1.5	-0.2	0.7
Medication: Ramipril	0.4	0.6	1.7	-0.8	-0.7	-0.3	-0.3	-0.5	-0.1	-0.6	-0.1	0.5	-1.1	-0.5	-1.2	-0.8	-1.0	-0.1	0.8	-0.5	-0.9	-1.0	-0.9	-1.3	-1.0	0.7	-0.9	-0.8
Father’s age at death	0.4	0.5	3.3	0.9	0.8	0.8	0.3	0.4	-0.4	0.1	0.1	1.8	-0.0	0.7	0.2	0.3	0.1	-1.1	-0.6	-0.5	0.8	0.6	0.8	0.0	0.7	0.8	0.6	0.8
Worrier / anxious feelings	0.4	0.8	9.6	0.2	0.2	0.4	1.1	0.5	0.7	0.7	1.2	3.1	-0.3	0.4	0.0	1.1	0.3	0.1	1.3	0.2	-0.3	0.3	0.5	0.6	0.7	0.8	0.7	0.4
Hair/balding pattern: Pattern 3	0.4	0.6	3.6	-0.9	-0.9	-1.1	-0.6	-0.5	-0.4	-0.8	-0.7	1.9	-0.8	-0.5	-0.7	-0.5	-0.3	-0.7	-0.8	-0.6	-0.6	-0.7	-0.6	-0.7	-0.5	0.3	-0.6	-0.5
Prospective memory result	0.4	0.5	1.6	0.8	0.9	0.6	0.1	1.1	1.0	-0.3	0.3	-0.7	0.9	0.1	0.8	0.0	1.0	1.3	-0.5	1.1	0.5	0.4	0.3	0.4	0.5	-0.8	0.2	0.7
Loud music exposure frequency	0.4	0.5	1.9	0.7	0.7	0.5	-0.3	0.5	0.4	1.4	0.8	-1.2	-0.4	0.6	-0.5	0.6	0.2	1.4	0.5	0.7	0.5	0.2	0.7	0.3	0.3	0.5	0.6	0.7
Mouth/teeth dental problems: Loose teeth	0.4	0.4	1.6	0.4	0.4	0.8	0.5	0.1	-0.0	0.5	0.7	0.7	-0.3	0.9	0.0	1.2	0.2	0.7	0.3	0.5	0.3	0.9	0.6	0.6	0.5	0.9	1.3	0.9
Mean time to correctly identify matches	0.4	0.8	2.8	-0.5	-0.5	-1.1	-0.9	-0.2	-0.2	-1.4	-1.0	-1.2	-0.4	-1.6	-0.7	-1.1	-1.0	0.2	-1.7	-0.0	-0.4	-0.9	-0.9	-1.1	-0.9	0.5	-1.0	-0.6
Comparative height size at age 10	0.4	2.2	4.3	-1.6	-1.6	-1.4	-1.3	-1.2	-1.0	-2.1	-1.7	-1.3	-1.2	-1.6	-1.3	-1.6	-1.7	-0.6	-1.3	-0.9	-1.4	-1.6	-1.7	-1.7	-1.8	-0.6	-1.6	-2.0
Number of full sisters	0.4	0.5	1.2	-0.5	-0.4	-0.2	-0.9	0.2	0.5	-0.9	-0.9	-1.0	0.5	-0.8	0.5	-1.1	0.4	-0.2	-0.3	-0.2	-0.3	-0.7	-0.9	-0.4	-0.6	-1.0	-1.1	-1.1
Knee pain experienced in last month	0.4	0.7	2.8	-0.4	-0.5	-1.4	-1.1	-0.7	-0.8	-0.4	-1.7	-1.3	0.5	-0.3	0.5	-0.7	-0.2	-0.8	-1.2	-0.2	-0.2	-0.6	-0.5	-0.2	-0.1	-1.3	-0.9	-1.0
Back pain experienced in last month	0.4	0.6	6.2	-0.6	-0.4	0.2	-0.2	-0.1	0.7	-0.6	0.2	0.0	0.7	-0.4	0.6	-1.0	0.4	0.4	0.5	0.4	-0.3	-0.5	-1.0	-0.1	-0.5	-2.5	-1.0	-1.3
Hearing aid user	0.4	0.4	2.8	-0.5	-0.5	-0.8	-0.7	-0.6	-0.5	-0.5	-0.2	-0.5	-0.5	-0.5	-0.4	-0.7	-0.2	-1.0	0.4	-0.8	-0.5	-0.7	-0.6	-0.5	-0.6	-0.5	-0.7	-1.7
Risk taking	0.4	0.6	3.6	0.6	0.6	0.2	0.0	0.5	0.7	0.7	0.5	-1.9	1.3	0.6	1.2	0.0	0.9	0.6	1.3	0.5	-0.0	0.7	0.4	0.8	0.5	-1.0	0.3	0.4
Commuting to job workplace: Cycle	0.4	0.5	1.4	-0.7	-0.6	-0.7	-1.0	-0.9	-1.1	-0.5	-0.3	0.6	-0.9	0.3	-1.0	-0.2	-0.7	-0.9	-0.5	-1.2	-0.7	-0.7	-0.4	-0.7	-0.7	0.5	-0.3	-0.5
Intelligence (Savage-Jansen 2018)	0.3	1.0	3.7	-0.7	-0.7	-1.9	-0.7	-0.7	-0.9	-0.9	-1.4	-1.1	-0.7	-0.7	-0.7	-0.7	-0.9	-1.5	-1.7	-1.7	-0.5	-0.8	-0.7	-0.7	-0.9	-0.5	-0.6	-0.7
Alzheimer’s Disease (in mother)	0.3	0.4	1.3	-0.8	-0.7	0.4	-1.1	-0.5	-0.3	-1.1	-0.2	-1.1	-0.1	-0.6	-0.0	-0.8	-0.2	-0.0	-0.7	0.2	-0.2	-0.6	-0.9	-1.0	-0.5	-0.0	-0.6	-0.0
Alzheimer’s Disease (including proxy)	0.3	0.5	1.9	0.3	0.4	1.4	0.1	0.5	0.5	-0.2	0.8	-0.3	0.8	0.9	1.1	0.4	0.8	0.8	-0.2	1.2	0.9	0.8	0.5	0.2	0.8	0.7	0.7	0.5
Mean Putamen Volume	0.3	0.3	1.6	-0.7	-0.6	0.4	-0.3	-0.2	0.5	-0.0	0.5	1.3	-0.7	-0.5	-0.6	0.0	-0.8	0.8	0.6	0.4	-0.9	-0.4	-0.4	-0.2	-0.3	-0.2	-0.1	-0.0
Blood Eosinophil Count	0.3	2.4	8.9	1.5	1.2	1.4	1.1	0.5	0.6	1.1	1.2	-2.1	3.0	1.1	2.7	0.6	1.9	1.0	1.4	2.4	1.9	1.6	1.3	1.6	2.0	0.6	0.8	-0.1
Lung FVC	0.3	1.5	3.3	1.1	1.1	0.9	1.2	1.2	1.4	1.2	1.0	0.2	1.8	1.2	1.7	1.1	1.1	0.7	1.6	1.3	1.4	1.3	1.0	1.4	1.4	1.1	1.0	0.8
Ever had hysterectomy (womb removed)	0.3	0.4	2.0	0.2	0.2	1.2	0.5	0.5	0.8	0.4	0.7	-0.9	0.1	0.4	0.1	0.3	0.3	0.8	1.0	0.6	0.6	0.1	0.2	0.4	0.2	1.4	0.0	-0.2
Diabetes (mother)	0.3	0.4	1.8	0.4	0.4	0.7	0.1	0.4	0.5	0.3	1.2	-0.3	1.3	0.7	0.8	0.0	0.4	0.7	1.0	0.6	0.0	0.3	0.2	0.6	0.3	-1.0	-0.0	0.4
Fed-up feelings	0.3	0.5	1.7	-0.3	-0.2	0.8	-0.9	-0.1	-0.0	-1.0	-0.5	1.2	1.3	-0.7	1.1	-0.8	-0.1	0.0	-0.2	0.5	-1.2	-0.3	-0.6	0.1	-0.0	-1.0	-0.8	-0.6
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	3.3	-0.5	-0.5	-0.7	-0.1	-0.2	0.5	-0.1	-0.1	-0.3	0.5	-0.6	0.2	-0.4	0.0	0.7	0.3	0.3	-0.6	-0.2	-0.7	0.2	-0.5	-1.8	-0.4	0.1
Serious illness, injury or assault to yourself	0.3	0.4	1.6	-0.3	-0.3	0.1	-0.7	-0.3	-0.2	-0.1	0.0	0.4	-0.7	-0.4	-0.8	-0.6	-0.8	-0.9	0.1	-1.1	-0.5	-0.6	-0.3	-0.6	-0.6	-1.3	-0.5	-1.2
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	2.7	-0.7	-0.7	-0.3	-0.5	-0.5	-0.4	-0.8	-0.6	0.9	-0.2	-0.6	-0.1	-0.3	-0.4	0.1	-0.8	0.1	-0.9	-0.5	-0.6	-0.2	-0.4	-1.6	-0.5	-0.1
Qualifications: None of the above	0.3	0.6	2.5	-0.1	-0.1	-0.7	-1.0	-0.6	-1.1	-0.8	-1.2	-1.6	0.4	-0.7	0.1	-1.4	-0.6	0.3	-1.0	0.1	-0.3	-0.9	-0.6	-0.7	-0.6	-0.7	-1.3	-0.1
Pain all over the body in last month	0.3	0.3	1.7	-0.2	-0.4	-0.4	-0.1	0.1	0.5	-0.0	0.1	-1.3	1.3	0.3	1.1	0.1	0.1	0.7	0.0	0.7	-0.6	0.4	-0.2	0.9	0.2	0.5	0.0	-0.5
Illnesses of mother	0.3	0.3	2.7	0.1	0.1	0.5	0.3	-0.1	-0.3	-0.2	-0.7	-1.6	0.7	0.4	0.8	0.2	0.3	-0.9	0.7	-0.4	0.0	0.2	0.1	0.7	0.3	-0.7	-0.0	-0.3
Pulse wave Arterial Stiffness index	0.3	0.4	1.8	0.8	0.6	1.3	0.1	0.3	-0.1	0.6	0.2	0.6	0.8	0.6	0.9	0.2	0.9	-0.4	-0.5	0.3	0.8	0.7	0.9	0.6	1.0	-0.1	0.4	0.2
Standing height	0.3	2.8	4.8	-1.8	-1.8	-2.2	-1.6	-1.5	-0.9	-1.4	-1.6	-1.3	-1.5	-1.7	-1.5	-1.7	-1.9	-1.2	-0.6	-1.5	-1.7	-1.9	-1.9	-1.7	-1.9	-2.2	-1.7	-1.9
Pulse wave reflection index	0.3	0.4	1.9	-0.6	-0.4	-0.6	-0.9	-0.1	-0.0	-0.8	-0.5	-0.5	-1.1	-0.6	-0.8	-0.8	-0.5	-0.5	-1.4	-0.7	-0.0	-0.6	-0.5	-0.8	-0.6	-0.0	-0.6	-0.5
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	2.4	-0.5	-0.7	-0.0	-0.5	-0.9	-0.3	0.2	-0.6	0.2	1.2	0.5	0.8	0.1	-0.0	-1.2	0.4	-0.2	0.1	-0.1	-0.1	0.5	0.4	0.4	-0.4	-1.5
Comparative body size at age 10	0.3	0.8	4.5	0.9	1.1	0.8	0.9	1.2	1.2	-0.0	1.2	-0.9	0.6	0.7	0.7	0.5	0.8	2.1	0.4	1.5	0.6	0.7	0.6	0.7	0.6	0.7	0.5	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	4.6	0.2	0.4	0.6	1.0	0.3	0.1	-0.1	0.8	2.1	-0.2	0.3	0.1	0.7	0.2	-0.1	-0.2	-0.1	0.7	0.4	0.5	0.4	0.4	-0.2	0.5	-0.1
Pulse wave peak to peak time	0.3	0.4	1.7	-0.7	-0.6	-1.3	0.0	-0.3	0.1	-0.5	-0.2	-0.5	-0.8	-0.5	-0.9	-0.1	-0.9	0.4	0.5	-0.3	-0.8	-0.6	-0.8	-0.5	-1.0	0.1	-0.3	-0.2
Eye problems/disorders: None of the above	0.3	0.3	2.6	0.7	0.6	0.3	-0.0	0.2	-0.5	0.2	0.0	0.9	0.4	0.5	0.3	-0.1	0.1	0.5	-0.5	0.6	0.6	0.3	0.6	0.1	0.5	1.6	0.1	0.8
Medication for pain relief, constipation, heartburn	0.3	0.4	3.0	0.1	0.0	0.1	0.8	0.0	0.7	1.1	0.1	-0.1	0.3	0.3	0.3	0.6	0.9	-1.0	1.7	-0.3	0.4	0.6	0.5	0.6	0.6	1.0	0.6	-0.7
Supplements: Vitamin C	0.3	0.4	3.3	0.1	0.1	-0.1	0.8	0.3	0.6	0.6	0.4	1.0	0.5	-0.3	0.4	0.7	0.3	0.6	1.8	0.3	0.2	0.1	0.0	0.5	0.2	-1.1	0.3	0.8
Illnesses of siblings: Diabetes	0.3	0.4	1.9	-0.1	-0.0	-0.2	0.5	0.8	1.4	-0.1	0.4	-0.6	0.6	0.1	0.5	0.1	0.7	1.3	1.2	0.8	0.1	0.2	-0.4	0.5	-0.1	-0.7	0.0	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.7	3.8	-0.8	-0.8	-0.4	-1.2	-0.4	0.2	-0.7	-0.7	-0.3	0.5	-0.9	0.3	-1.0	-0.4	0.3	0.0	0.2	-0.6	-0.9	-1.2	-0.4	-0.7	-1.9	-1.2	-1.2
Average weekly red wine intake	0.3	0.4	1.4	-0.9	-1.1	-0.4	-0.4	-1.2	-1.0	-0.1	-0.2	-0.7	-0.9	-0.5	-0.6	-0.2	0.1	-0.5	-0.0	-0.6	-1.0	-0.4	-0.6	-0.6	-0.6	0.4	-0.2	-0.0
Mood swings	0.3	0.6	1.5	0.5	0.6	1.2	-0.2	0.8	1.0	0.6	0.8	0.4	1.0	0.4	1.0	0.4	0.6	1.1	0.8	1.2	-0.6	0.4	0.4	0.9	0.8	-1.0	0.3	0.5
Loneliness, isolation	0.3	0.5	2.9	-0.4	-0.5	0.5	-0.7	-0.3	0.2	-0.6	-0.2	1.7	1.4	-0.2	1.1	-0.4	0.4	0.2	0.6	0.7	-0.4	-0.1	-0.5	0.3	0.1	-1.4	-0.5	-0.7
Ever had bowel cancer screening	0.3	0.4	1.2	-0.7	-0.7	0.2	-0.6	-0.8	-1.1	-0.5	-0.3	0.8	-0.7	-0.1	-0.5	-0.2	-0.7	-0.6	-1.1	-0.4	-0.9	-0.6	-0.4	-0.5	-0.3	0.3	-0.4	-0.1
Osteoporosis (self-reported)	0.3	0.4	1.9	0.6	0.7	1.4	0.9	0.5	0.4	0.8	0.7	0.6	0.0	0.5	0.3	0.6	0.6	0.6	0.6	0.4	0.2	0.6	0.5	0.5	0.5	-0.1	0.6	0.6
Medication: Gliclazide	0.3	0.3	0.6	-0.6	-0.7	-0.2	-0.5	-0.7	-0.2	-0.4	-0.7	0.1	-0.0	-0.7	-0.4	-0.7	-0.8	0.0	0.3	-0.1	-0.4	-0.7	-0.7	-0.7	-0.7	-0.8	-0.8	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	2.5	0.6	0.7	1.1	1.0	0.6	0.6	0.7	0.9	-1.4	0.2	0.7	0.4	0.8	0.2	0.1	1.2	0.5	1.3	0.7	0.8	0.6	0.7	1.6	0.6	-0.0
Age started oral contraceptive pill	0.3	0.4	0.9	-0.5	-0.5	-0.9	-0.0	-0.5	-0.7	-0.9	-0.7	0.2	-0.7	-0.7	-0.4	-0.6	-0.7	-0.7	-0.8	-0.4	0.1	-0.7	-0.4	-0.7	-0.3	0.2	-0.7	-0.6
Pack years of smoking	0.3	0.5	2.3	-0.3	-0.4	-0.9	-1.2	-0.4	-0.6	-0.4	-1.1	-1.5	-0.1	-0.6	-0.1	-0.7	-0.4	-0.4	-1.0	-0.6	-0.3	-0.7	-0.5	-0.6	-0.5	-0.0	-0.7	-0.7
Bipolar Disorder (2018)	0.2	0.3	1.1	-0.1	-0.0	-0.1	-0.3	-0.2	-0.3	-0.2	0.5	0.4	-1.1	-0.8	-1.0	-0.6	-0.6	0.5	-0.3	0.3	-0.7	-0.4	-0.3	-0.9	-0.5	-0.3	-0.2	0.6
Schizophrenia (2018)	0.2	0.5	3.9	0.5	0.6	2.0	0.3	0.4	0.5	0.4	1.1	0.2	0.2	0.5	0.2	0.6	0.4	0.0	0.4	0.4	-0.0	0.7	0.6	0.4	0.6	1.4	0.7	-0.2
Verbal and Numeric Reasoning (VNR)	0.2	0.4	1.7	-0.6	-0.7	-0.9	-0.2	-0.3	0.0	-0.6	-0.7	-0.7	0.7	-0.2	0.7	-0.5	-0.2	-1.3	-0.3	-1.1	-0.9	-0.2	-0.6	0.3	-0.4	-0.4	-0.5	-1.2
Bipolar Disorder (2011)	0.2	0.1	0.9	-0.3	-0.3	-0.0	-0.5	-0.4	-0.3	-0.1	0.5	0.5	0.0	-0.3	0.2	-0.3	0.0	0.3	0.2	0.4	-0.9	-0.2	-0.4	-0.2	-0.2	0.0	-0.4	-0.8
Primary Biliary Cirrhosis	0.2	0.3	1.6	-0.1	-0.2	-1.3	-0.1	-0.5	-1.1	-0.4	-0.9	-0.5	-0.0	-0.1	-0.0	-0.2	-0.5	-0.7	-1.2	-0.4	0.3	-0.2	0.0	-0.1	-0.2	1.2	-0.1	-0.5
Blood Red Count	0.2	1.5	8.8	-1.1	-1.4	-3.0	-1.1	-0.6	-0.1	-1.5	-2.6	-1.1	0.9	-1.1	0.6	-1.4	-0.2	-0.2	-1.1	0.2	-1.0	-0.8	-1.3	-0.6	-0.6	-1.6	-1.4	-0.6
Heel T-Score	0.2	1.9	4.6	-1.8	-1.9	-0.3	-1.0	-1.6	-1.0	-1.1	-1.4	1.4	-1.2	-1.1	-1.3	-1.1	-1.2	-1.3	-0.4	-1.2	-2.1	-1.4	-1.6	-1.5	-1.4	-0.9	-1.2	-1.9
Hair Pigment	0.2	5.6	15.1	2.5	2.5	1.9	1.4	2.8	2.8	1.0	1.7	-0.8	3.9	1.1	3.8	0.6	3.3	3.7	1.0	3.8	2.1	2.1	1.7	2.7	2.4	-0.7	1.0	2.2
Hand grip strength (left)	0.2	0.6	1.7	-1.2	-1.2	-0.4	-0.4	-1.1	-0.3	-0.4	-0.1	-0.4	-0.1	-0.6	-0.2	-0.6	-1.0	-0.1	0.4	-0.2	-0.8	-0.6	-1.2	-0.3	-0.9	-1.3	-0.7	-1.3
Relative age of first facial hair	0.2	0.4	1.7	-0.7	-0.7	-0.6	-0.7	-0.4	0.1	-0.3	-0.2	0.5	-1.0	-0.5	-0.8	-0.6	-0.3	-0.4	-0.4	-0.7	-0.9	-0.6	-0.6	-0.5	-0.8	-0.2	-0.5	-1.3
Severe depression (siblings)	0.2	0.2	1.1	-0.4	-0.4	0.6	-1.0	-0.4	-0.3	-0.2	-0.1	-0.8	0.4	-0.4	0.2	-0.3	-0.1	0.2	-0.4	0.4	-0.7	-0.3	-0.3	-0.1	-0.0	0.8	-0.4	-0.3
Pack years adult smoking proportion	0.2	0.3	2.5	-0.2	-0.3	-0.7	-1.2	-0.2	-0.2	-0.2	-0.9	-1.6	0.1	-0.4	0.1	-0.6	-0.2	-0.4	-0.5	-0.4	-0.2	-0.6	-0.5	-0.4	-0.4	-0.3	-0.6	-0.7
Maternal smoking around birth	0.2	0.3	2.9	0.2	0.2	1.7	-0.4	-0.2	-0.9	-0.5	-0.5	-0.1	0.4	-0.0	0.0	-0.6	-0.4	0.4	-0.9	0.1	0.4	-0.4	-0.0	-0.3	-0.2	0.2	-0.5	1.0
Relative age voice broke	0.2	0.3	1.7	-0.1	-0.1	0.1	0.4	0.3	0.9	0.7	0.7	1.1	-1.3	0.1	-0.9	0.3	0.0	-0.3	0.7	-0.8	-0.1	0.2	0.1	0.1	-0.3	0.2	0.5	-0.8
Sitting height	0.2	1.1	5.6	-1.2	-1.4	-1.4	-1.0	-0.9	-0.1	-0.7	-0.7	-0.4	-0.1	-0.8	-0.3	-0.9	-0.9	-1.2	0.4	-0.8	-1.2	-1.0	-1.3	-0.7	-0.9	-1.1	-1.1	-2.4
Chronic bronchitis/emphysema (father)	0.2	0.2	0.6	0.4	0.4	0.8	0.3	0.7	0.8	-0.1	0.7	0.3	-0.2	0.6	0.1	0.3	0.5	0.5	-0.2	0.7	0.2	0.5	0.5	0.2	0.5	0.6	0.5	-0.0
Number of incorrect matches in round	0.2	0.3	1.2	0.5	0.6	-0.0	0.4	0.4	0.3	0.2	1.0	-0.4	-0.5	-0.4	-0.3	0.5	0.2	0.9	0.3	1.0	1.1	0.5	0.5	-0.3	0.4	1.1	0.6	0.1
Heart attack	0.2	0.3	3.2	0.4	0.5	0.2	-0.4	0.4	-0.1	-0.3	0.3	-0.7	-0.1	-0.2	0.0	-0.1	-0.3	1.0	-1.8	0.5	0.1	-0.0	0.2	-0.1	0.1	0.1	0.1	1.2
Medication: Simvastatin	0.2	0.4	1.2	-0.3	-0.4	-1.0	-0.5	-0.1	-0.0	-0.3	-0.1	1.1	-0.6	-0.9	-0.5	-0.7	-0.7	0.3	-0.8	-0.4	-0.3	-0.7	-0.7	-0.4	-0.8	-0.7	-0.6	-0.5
Neuroticism score	0.2	0.5	1.6	0.4	0.5	0.8	0.2	0.8	0.9	0.6	1.0	1.3	0.6	0.7	0.8	0.9	0.8	0.2	0.8	0.5	-0.5	0.5	0.5	0.9	0.9	0.0	0.6	0.2
Forced expiratory volume in 1-second (FEV1)	0.2	0.5	3.2	0.0	0.1	0.5	0.4	0.6	1.4	0.9	1.1	-0.7	0.5	1.0	0.5	0.7	0.6	0.7	1.8	0.7	0.3	0.4	0.1	0.5	0.4	-0.4	0.5	0.5
Happiness	0.2	0.3	1.3	0.2	0.2	-0.3	0.1	0.4	0.4	0.5	0.7	0.3	-0.0	1.1	0.0	0.9	-0.5	0.2	0.7	0.5	-0.1	0.3	0.6	0.2	0.6	1.0	0.6	-0.1
Qualifications: A levels/AS levels or equivalent	0.2	0.5	1.4	-0.2	-0.2	-0.6	1.1	0.2	0.9	0.7	1.2	0.6	-0.4	0.5	-0.4	1.2	0.1	-0.5	1.1	-0.6	0.6	0.9	0.2	0.6	0.1	0.7	1.2	-0.6
Depression (self-reported)	0.2	0.2	2.6	-0.4	-0.3	0.4	0.2	-0.3	-0.1	0.2	0.4	0.5	-0.1	0.3	-0.1	0.4	-0.0	0.2	0.2	-0.2	-0.8	-0.2	-0.4	0.1	-0.2	-1.6	-0.0	-0.2
Exposure to tobacco smoke at home	0.2	0.3	2.3	-0.2	-0.1	0.0	0.3	0.1	0.1	-0.2	0.2	0.6	-1.5	-0.2	-1.3	0.2	-0.4	0.1	-0.0	-0.6	0.1	-0.1	-0.1	-0.5	-0.5	0.4	0.3	0.7
Breastfed as a baby	0.2	0.3	1.4	-0.1	-0.1	-0.2	-0.3	-0.7	-1.2	0.0	0.0	0.6	-1.0	-0.4	-0.7	-0.3	-0.2	-0.4	-0.6	-0.8	0.1	-0.4	-0.1	-0.7	-0.5	-0.4	-0.2	0.3
Peak expiratory flow (PEF)	0.2	0.6	4.0	-0.2	-0.2	0.4	0.4	0.0	0.8	1.4	0.8	1.0	0.1	1.3	0.2	1.1	0.3	0.0	2.0	0.1	0.1	0.5	0.2	0.9	0.4	-0.3	0.9	0.1
Qualifications: O levels/GCSEs or equivalent	0.2	0.4	0.9	0.3	0.3	-0.2	0.7	0.6	0.7	0.2	0.9	-0.8	0.9	0.8	0.7	0.6	0.5	0.7	0.7	0.9	0.7	0.6	0.3	0.6	0.4	0.4	0.5	-0.0
Headache pain in last month	0.2	0.3	1.8	0.7	0.6	0.1	0.2	0.2	-0.6	0.2	0.4	0.1	0.2	1.2	0.2	0.5	0.2	-0.2	-1.3	-0.2	0.8	0.5	0.7	0.4	0.4	1.0	0.5	0.1
Number of full brothers	0.2	0.2	1.0	-0.1	-0.1	-0.1	-0.4	-0.3	-0.5	0.2	-0.9	-0.7	0.6	-0.0	0.2	-0.1	0.0	-0.9	0.2	-0.3	-1.0	-0.2	0.0	0.0	0.2	-0.8	-0.3	-0.3
Wheeze or whistling in the chest in last year	0.2	0.3	2.4	-0.3	-0.4	-0.1	-0.1	-0.8	-0.6	0.8	-0.3	-1.5	-0.5	0.1	-0.5	0.1	-0.8	-0.2	1.0	-0.4	-0.4	-0.4	-0.1	-0.1	-0.3	-0.3	-0.2	-0.8
Health satisfaction	0.2	0.3	2.8	-0.2	-0.2	-0.7	-0.5	0.3	0.6	-0.5	-0.2	-1.7	-0.4	0.3	-0.3	-0.2	-0.2	0.9	0.2	0.4	-0.4	-0.3	-0.3	-0.3	-0.3	-0.2	-0.2	-0.4
Neck or shoulder pain in last month	0.2	0.3	1.8	0.5	0.3	-0.2	-0.3	-0.4	-1.2	-0.6	-0.7	0.1	0.3	-0.6	0.3	-0.6	0.2	-0.8	-1.3	-0.3	0.8	0.0	0.1	-0.4	0.3	-0.4	-0.3	-0.2
Heart disease (mother)	0.2	0.3	1.6	0.4	0.5	0.9	0.3	0.8	0.9	0.4	0.9	0.3	-0.3	-0.5	0.0	-0.2	0.5	1.3	-0.2	0.8	0.0	0.1	0.0	-0.1	0.0	0.3	0.0	-0.1
Pulse rate, automated reading	0.2	0.5	2.6	-1.2	-1.2	0.3	-0.4	-0.9	-0.4	-0.3	-1.0	0.9	0.1	-0.2	-0.1	-0.4	-0.6	-0.1	0.5	0.0	-0.7	-0.7	-1.0	-0.4	-0.5	-1.6	-0.9	0.2
Had major operations	0.2	0.2	0.8	-0.2	-0.3	0.0	-0.4	-0.3	-0.7	-0.8	-0.5	-0.7	-0.6	-0.4	-0.4	-0.2	-0.5	-0.2	-0.9	-0.2	-0.8	-0.1	-0.1	-0.6	-0.2	0.8	-0.0	0.0
Age at last live birth	0.2	0.3	2.3	-0.7	-0.5	0.6	-0.2	-0.4	0.1	-0.3	-0.0	0.4	0.4	0.1	0.2	-0.4	-0.0	-0.5	1.3	-0.2	-0.2	-0.4	-0.5	0.3	-0.2	-1.5	-0.6	-0.8
Smoking status: Previous	0.2	0.2	1.7	0.4	0.3	0.0	-0.0	0.0	-0.6	-0.2	-0.0	-0.2	0.6	-0.3	0.6	-0.6	0.2	0.2	-1.1	-0.1	0.8	0.1	0.1	0.4	-0.0	-1.3	-0.3	0.2
Long-standing illness, disability or infirmity	0.2	0.3	2.3	0.0	0.0	0.6	-0.2	0.2	0.6	-0.3	0.1	-0.1	1.2	0.1	1.0	-0.2	0.3	1.5	-0.1	1.2	0.0	0.1	-0.2	0.7	0.1	-0.5	-0.2	0.2
Diabetes diagnosed by doctor	0.2	0.4	1.2	-0.8	-0.7	-0.2	-0.4	-0.3	0.2	-0.7	-0.0	0.0	-0.7	-0.6	-0.8	-0.9	-1.1	0.3	0.3	-0.2	-0.6	-0.8	-1.0	-0.8	-1.0	-0.1	-0.8	-0.4
Qualifications: nursing, teaching	0.2	0.4	2.7	-0.8	-0.9	-0.8	-0.2	-0.4	0.4	0.0	-0.2	-1.6	0.2	-0.4	0.4	-0.2	0.5	-0.5	0.5	-0.1	-0.9	-0.1	-0.9	0.2	-0.4	-1.2	-0.3	-0.5
Eye problems/disorders: Cataract	0.2	0.3	1.2	-0.2	-0.2	0.4	0.7	-0.0	0.4	0.4	0.2	-0.6	-0.9	0.3	-0.6	0.9	0.1	-0.0	1.0	-0.2	-0.5	0.4	0.1	0.1	-0.0	-1.1	0.9	0.0
Illnesses of father: None of the above (group 1)	0.2	0.2	1.5	0.2	0.2	-0.4	-0.8	0.3	0.0	-0.5	-0.4	-1.2	-0.1	-0.2	-0.2	-0.6	0.1	-0.3	-1.2	-0.6	0.1	-0.2	-0.1	-0.4	-0.2	-0.3	-0.4	-0.1
Ever taken oral contraceptive pill	0.2	0.2	1.4	-0.5	-0.6	-0.7	-0.4	-0.2	0.4	0.0	0.5	0.6	0.7	-0.4	0.5	-0.3	-0.3	0.2	0.4	0.2	-0.1	0.1	-0.6	0.4	-0.2	-1.2	-0.2	-0.2
Pain type(s) experienced in last month: Hip pain	0.2	0.3	1.7	0.3	0.3	-0.3	0.3	-0.3	-0.8	0.7	0.2	1.3	-0.6	0.2	-0.5	0.4	-0.2	-0.9	-0.5	-0.9	0.4	0.0	0.5	-0.1	0.2	-0.1	0.2	-0.1
Alcohol drinker status: Never	0.2	0.2	1.5	-0.6	-0.7	-0.2	0.0	-0.2	0.5	0.3	-0.2	1.2	-0.0	-0.6	-0.1	0.1	-0.5	0.2	0.7	0.1	-0.6	0.0	-0.4	0.3	-0.3	-0.2	0.1	0.2
Average weekly beer plus cider intake	0.2	0.3	3.8	-0.1	-0.2	0.1	-0.0	-0.2	-0.2	0.1	0.2	0.9	0.9	0.1	0.8	-0.1	0.3	-0.4	0.8	0.3	-0.3	-0.1	-0.2	0.3	0.3	-1.9	-0.3	-0.6
Heart attack/myocardial infarction (self-reported)	0.2	0.3	3.3	0.2	0.3	-0.2	-0.6	0.2	-0.2	-0.5	0.2	-0.9	-0.2	-0.4	-0.1	-0.3	-0.4	0.6	-1.8	0.3	-0.0	-0.2	0.0	-0.3	-0.1	-0.0	-0.2	0.7
Bipolar Disorder or Schizophrenia	0.1	0.3	2.2	0.3	0.4	1.5	0.1	0.1	0.2	0.2	1.2	0.4	-0.6	-0.1	-0.4	0.1	-0.1	0.4	0.1	0.5	-0.5	0.4	0.3	-0.3	0.2	0.9	0.4	0.3
Schizophrenia vs Biploar Disorder	0.1	0.1	0.9	-0.3	-0.3	0.6	-0.4	-0.3	-0.2	-0.2	-0.2	0.4	0.2	0.4	-0.0	-0.1	-0.3	-0.9	-0.4	-0.4	0.3	-0.2	-0.1	-0.0	-0.0	0.2	-0.2	-0.9
Ovarian Cancer	0.1	0.2	1.3	-0.0	-0.0	-0.1	0.1	0.5	1.1	0.3	0.2	0.5	-0.2	0.0	0.0	0.3	0.0	0.5	0.6	0.1	0.3	0.2	-0.0	0.4	-0.1	1.1	0.3	-0.3
Rheumatoid Arthritis	0.1	0.1	0.6	0.4	0.4	-0.3	0.4	0.7	0.4	-0.1	0.4	-0.1	-0.2	0.7	-0.3	0.6	0.4	0.2	-0.1	0.3	0.7	0.2	0.4	0.2	0.4	0.3	0.4	0.2
Schizophrenia (2014)	0.1	0.2	1.9	-0.0	0.0	1.4	-0.0	-0.3	-0.1	-0.1	0.6	-0.3	0.1	0.1	0.0	0.1	-0.2	-0.5	-0.1	0.2	-0.0	0.4	0.2	0.0	0.2	1.3	0.2	-0.9
Triglycerides	0.1	0.2	1.3	-0.5	-0.6	-1.1	-0.0	-0.4	-0.1	-0.3	-0.7	0.0	-0.6	-0.4	-0.5	-0.3	-0.6	-0.4	-0.2	-0.5	-0.0	-0.3	-0.4	-0.5	-0.5	0.3	-0.4	-0.8
Waist Hip Ratio (WHR)	0.1	0.5	7.3	-0.4	-0.5	0.1	-0.5	-0.4	-0.1	-0.0	-0.8	-0.9	1.0	-0.2	0.6	-0.3	0.2	-0.1	0.7	-0.2	-0.2	-0.3	-0.4	0.4	-0.2	-2.7	-0.5	-0.1
Type 2 Diabetes (T2D) (2018)	0.1	0.3	1.6	0.2	0.2	0.2	0.6	0.5	0.8	0.2	0.6	0.2	0.4	0.8	0.2	0.3	-0.1	0.9	1.3	0.7	0.3	0.4	0.1	0.5	0.1	0.7	0.3	-0.3
Lung FEV1/FVC ratio	0.1	0.4	3.8	-0.2	-0.0	0.7	-1.3	0.2	0.4	-0.3	0.5	-1.9	-0.1	0.2	-0.4	-0.5	-0.3	0.3	-0.8	-0.3	-0.2	-0.4	-0.3	-0.0	-0.6	-0.7	-0.5	-0.5
Chronotype (morning person)	0.1	0.2	1.0	0.0	0.1	-0.3	-0.2	0.5	0.5	0.3	0.5	0.1	-0.9	-0.1	-0.8	0.0	-0.2	0.6	-1.0	-0.3	0.1	-0.3	-0.0	-0.3	-0.4	0.6	0.1	0.5
Tanning	0.1	0.8	2.6	0.8	0.9	0.5	0.3	1.0	0.8	1.1	0.4	-1.1	0.8	0.6	0.8	0.5	0.9	1.4	1.0	0.9	0.3	0.3	0.4	0.8	0.5	-1.6	0.3	1.5
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.8	0.0	0.1	0.1	-0.1	-0.1	-0.2	-0.1	-0.2	0.9	-0.4	0.2	-0.5	-0.1	-0.2	-0.3	-0.7	-0.2	0.6	-0.3	0.1	-0.3	-0.1	0.4	-0.2	-0.5
Medication: Metformin	0.1	0.2	2.2	0.1	0.1	0.6	0.8	0.2	0.5	0.0	0.1	0.2	0.5	0.0	0.3	-0.2	-0.3	0.6	1.5	0.5	0.5	0.1	-0.2	0.1	-0.1	-0.3	-0.2	-0.3
Diabetes (father)	0.1	0.1	0.6	-0.2	-0.3	-0.5	0.6	0.0	0.4	-0.2	-0.1	-0.3	-0.0	-0.4	0.1	0.1	-0.2	0.3	0.8	0.4	-0.4	0.2	-0.1	0.0	-0.0	0.5	0.1	-0.2
Hand grip strength (right)	0.1	0.2	1.5	-0.3	-0.3	0.0	0.6	-0.2	0.4	0.5	0.1	-0.1	0.0	0.2	0.3	0.0	0.1	-0.1	1.2	-0.0	-0.3	0.1	-0.3	0.3	-0.1	-0.9	-0.1	-0.7
Age when periods started (menarche)	0.1	0.3	2.2	0.4	0.4	-0.3	-0.2	-0.1	-1.0	0.6	-0.4	1.4	-0.0	0.2	-0.0	0.4	-0.1	-0.3	-1.0	-0.3	0.1	-0.2	0.4	0.3	0.3	-1.5	0.2	0.8
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	0.6	-0.3	-0.2	-0.1	-0.2	0.0	-0.0	-0.7	-0.3	0.0	-0.7	-0.5	-0.6	-0.5	-0.3	-0.7	-0.2	-0.8	0.3	-0.4	-0.2	-0.6	-0.4	-0.6	-0.3	-0.7
Past tobacco smoking	0.1	0.2	1.5	-0.5	-0.4	-0.5	-0.2	-0.1	0.5	-0.2	-0.3	-0.3	-0.9	-0.1	-0.8	0.2	-0.5	-0.4	0.7	-0.1	-0.4	-0.3	-0.1	-0.6	-0.1	1.2	0.1	-0.3
Forced vital capacity (FVC)	0.1	0.3	2.0	-0.2	-0.2	-0.2	0.2	0.3	0.9	0.3	0.5	-0.9	0.8	0.4	0.8	0.1	0.5	0.3	1.4	0.6	0.2	0.2	-0.3	0.2	0.2	-0.5	0.0	0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.1	0.7	-0.1	-0.0	-0.4	0.4	0.3	0.4	0.2	0.2	0.2	-0.9	0.2	-0.7	0.4	-0.1	-0.5	0.3	-0.6	0.6	0.1	0.2	-0.0	-0.1	-0.4	0.4	-0.5
Fluid intelligence score	0.1	0.3	1.3	-0.6	-0.6	-0.9	-0.0	-0.3	-0.0	0.0	-0.5	0.0	-0.6	-0.1	-0.5	0.1	-0.6	-1.1	0.2	-1.2	-0.6	-0.3	-0.4	-0.1	-0.5	-0.4	-0.1	-0.5
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	1.3	-0.5	-0.5	-0.3	-0.7	-0.6	-0.2	0.1	-0.5	0.6	0.0	-0.0	-0.0	-0.0	-0.1	-1.1	-0.4	-0.4	-0.2	0.1	-0.1	0.3	0.0	-0.4	0.1	-1.1
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.2	0.9	-0.4	-0.3	-0.0	0.4	-0.1	0.3	0.3	0.4	0.7	0.2	-0.0	0.1	0.3	-0.2	-0.7	1.0	-0.2	-0.6	0.1	-0.2	0.0	0.0	0.1	0.0	-0.9
Asthma	0.1	0.1	1.3	-0.2	-0.2	0.1	0.4	-0.2	0.2	0.0	0.3	-0.1	-0.1	0.1	0.0	0.3	-0.3	0.0	1.1	0.1	0.3	0.1	-0.2	0.1	-0.0	-0.8	0.2	-0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.2	2.5	-0.5	-0.4	0.2	-0.0	0.1	0.7	0.3	0.4	-1.6	-0.1	0.3	-0.2	0.0	-0.3	-0.2	1.3	-0.3	-0.3	-0.2	-0.5	-0.1	-0.3	-0.1	-0.2	-0.3
Forced vital capacity (FVC), Best measure	0.1	0.5	2.7	-0.9	-0.9	-0.7	-0.4	-0.5	0.1	-0.2	-0.3	-1.6	-0.2	-0.5	-0.4	-0.6	-0.7	-0.7	0.9	-0.6	-0.5	-0.7	-1.0	-0.6	-0.8	0.1	-0.7	-1.1
Age at first live birth	0.1	0.1	0.3	-0.3	-0.2	0.5	-0.1	-0.3	-0.2	-0.1	0.1	0.2	0.4	0.4	0.6	-0.1	0.4	-0.5	0.5	0.1	-0.3	0.1	0.1	0.6	0.3	-0.5	-0.1	-0.1
Qualifications: College or University degree	0.1	0.4	2.3	-0.6	-0.7	-0.9	0.3	-0.6	-0.4	0.1	-0.7	1.5	0.4	-0.3	0.2	0.2	0.0	-1.3	-0.1	-1.4	0.0	0.0	-0.3	0.5	-0.4	0.0	-0.0	-0.6
Family relationship satisfaction	0.1	0.1	0.6	-0.2	-0.2	0.3	-0.5	-0.1	0.6	0.3	0.1	0.2	0.4	0.6	0.3	0.3	-0.2	0.2	0.6	0.4	0.1	0.3	-0.1	0.4	0.2	-0.7	0.2	-0.8
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.7	0.2	0.2	0.1	-0.1	0.5	0.8	0.4	0.2	-0.1	0.6	-0.1	0.3	-0.3	0.4	0.5	0.6	0.6	0.2	0.1	0.1	0.2	0.3	-0.5	-0.2	0.3
Mineral and other dietary supplements	0.1	0.1	0.4	-0.1	-0.1	-0.3	0.1	0.2	0.6	-0.0	0.4	0.1	-0.4	0.2	-0.3	0.2	-0.0	0.6	0.2	0.5	0.1	0.4	-0.0	0.2	-0.0	-0.4	0.5	-0.4
Asthma (self-reported)	0.1	0.2	1.8	-0.1	-0.1	0.2	0.6	-0.1	0.5	0.2	0.4	-0.2	-0.0	0.1	0.1	0.3	-0.1	0.3	1.3	0.3	0.4	0.2	-0.1	0.2	0.0	-0.9	0.3	-0.6
Irritability	0.1	0.1	0.5	-0.1	-0.2	0.3	-0.6	-0.2	-0.2	-0.1	-0.3	0.4	0.6	-0.2	0.3	-0.3	-0.3	-0.6	0.1	-0.2	-0.7	-0.3	-0.0	-0.1	0.1	0.1	-0.5	-0.2
Cholesterol lowering medication	0.1	0.2	1.3	-0.3	-0.4	-0.5	-0.1	0.2	0.6	-0.6	-0.1	0.4	0.1	-0.2	0.2	-0.6	0.0	-0.1	0.2	-0.2	-0.1	-0.2	-0.5	-0.2	-0.4	-0.4	-0.5	-1.1
Alcohol intake frequency.	0.0	0.1	0.4	0.4	0.2	-0.6	-0.2	0.5	0.4	0.2	-0.4	0.3	0.1	-0.2	0.1	-0.3	0.2	0.2	-0.4	0.2	0.1	0.3	0.2	0.1	0.2	0.2	0.1	0.0

Hub : Genes

C1orf50

Models

Trait associations