Best TWAS P=8.12e-20 · Best GWAS P=1.35e-34 conditioned to 2.47e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | NELFCD | 0.32 | 0.20 | enet | 8 | 0.27 | 2.1e-18 | 4.3 | -5.1 | 2.7e-07 | 0.22 | 1.00 | 0.00 | TRUE |
| 2 | GTEx | Nerve Tibial | NELFCD | 0.30 | 0.17 | enet | 25 | 0.23 | 2.8e-16 | 3.9 | -5.5 | 4.2e-08 | 0.27 | 1.00 | 0.00 | FALSE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | TH1L | 0.08 | 0.05 | lasso | 3 | 0.07 | 8.1e-05 | 4.3 | -5.2 | 2.1e-07 | 0.14 | 0.01 | 0.98 | TRUE |
| 4 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | ZNF831 | 0.22 | 0.03 | enet | 6 | 0.15 | 9.0e-05 | -12.0 | 9.1 | 8.1e-20 | -0.65 | 0.02 | 0.63 | TRUE |