Best TWAS P=7.75e-08 · Best GWAS P=3.73e-08 conditioned to 1.07e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Hypothalamus | PDE1A | 0.24 | -0.01 | enet | 21 | -0.01 | 7.6e-01 | -3.4 | -5.2 | 1.5e-07 | -0.24 | 0.08 | 0.09 | TRUE |
| 2 | GTEx | Skin Not Sun Exposed Suprapubic | UBE2E3 | 0.25 | 0.06 | enet | 39 | 0.12 | 2.5e-07 | -4.5 | -5.1 | 2.7e-07 | 0.07 | 0.07 | 0.91 | FALSE |
| 3 | NTR | Blood | UBE2E3 | 0.02 | 0.00 | bslmm | 446 | 0.00 | 1.1e-02 | -4.6 | -5.4 | 7.7e-08 | 0.03 | 0.04 | 0.76 | TRUE |