TWAS
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Traits
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High blood pressure
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chr2:181,139,278-184,084,221
Best TWAS P=7.75e-08 · Best GWAS P=3.73e-08 conditioned to 1.07e-11
181M
181.5M
182M
182.5M
183M
183.5M
184M
0
2
4
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
NTR
Blood
UBE2E3
0.02
0.00
bslmm
446
0.00
1.1e-02
-4.6
-5.4
7.7e-08
0.03
0.04
0.76
TRUE
1
GTEx
Brain Hypothalamus
PDE1A
0.24
-0.01
enet
21
-0.01
7.6e-01
-3.4
-5.2
1.5e-07
-0.24
0.08
0.09
TRUE
2
GTEx
Skin Not Sun Exposed Suprapubic
UBE2E3
0.25
0.06
enet
39
0.12
2.5e-07
-4.5
-5.1
2.7e-07
0.07
0.07
0.91
FALSE