Best TWAS P=1.08e-07 · Best GWAS P=5.78e-09 conditioned to 0.0024
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | EEFSEC | 0.07 | 0.04 | blup | 496 | 0.04 | 1.2e-05 | -3.6 | 5.2 | 1.7e-07 | -0.59 | 0.23 | 0.76 | FALSE |
2 | GTEx | Cells Transformed fibroblasts | RUVBL1 | 0.07 | 0.04 | lasso | 3 | 0.02 | 2.5e-02 | -5.2 | -5.3 | 1.1e-07 | 0.67 | 0.08 | 0.90 | TRUE |