TWAS
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High blood pressure
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chr3:127,097,277-128,821,807
Best TWAS P=1.08e-07 · Best GWAS P=5.78e-09 conditioned to 0.0024
127M
127.2M
127.4M
127.6M
127.8M
128M
128.2M
128.4M
128.6M
128.8M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Cells Transformed fibroblasts
RUVBL1
0.07
0.04
lasso
3
0.02
2.5e-02
-5.2
-5.3
1.1e-07
0.67
0.08
0.90
TRUE
1
CommonMind
Brain Pre-frontal Cortex
EEFSEC
0.07
0.04
blup
496
0.04
1.2e-05
-3.6
5.2
1.7e-07
-0.59
0.23
0.76
FALSE