Best TWAS P=7.27e-09 · Best GWAS P=1.26e-07 conditioned to 0.286
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | RP11-538P18.2 | 0.17 | 0.14 | enet | 24 | 0.21 | 3.7e-16 | 4.4 | -5.8 | 7.3e-09 | -0.80 | 0.09 | 0.88 | TRUE |
| 2 | GTEx | Brain Cerebellar Hemisphere | RP11-538P18.2 | 0.17 | 0.11 | lasso | 4 | 0.04 | 4.1e-02 | 5.2 | -5.5 | 2.9e-08 | -0.95 | 0.02 | 0.76 | FALSE |
| 3 | GTEx | Cells Transformed fibroblasts | RP11-538P18.2 | 0.10 | 0.08 | enet | 10 | 0.13 | 5.1e-10 | 4.5 | -5.3 | 1.2e-07 | -0.82 | 0.04 | 0.95 | FALSE |
| 4 | GTEx | Ovary | RP11-538P18.2 | 0.23 | 0.08 | lasso | 6 | 0.13 | 4.5e-04 | 4.5 | -5.2 | 1.7e-07 | -0.87 | 0.03 | 0.59 | FALSE |
| 5 | GTEx | Vagina | RP11-538P18.2 | 0.25 | 0.19 | lasso | 3 | 0.18 | 6.7e-05 | 5.3 | -5.5 | 5.1e-08 | -0.99 | 0.01 | 0.92 | FALSE |
| 6 | METSIM | Adipose | RSRC1 | 0.14 | 0.19 | blup | 532 | 0.21 | 6.0e-31 | 4.5 | -5.5 | 3.9e-08 | -0.59 | 0.14 | 0.82 | FALSE |