Best TWAS P=3.98e-08 · Best GWAS P=9.77e-08 conditioned to 0.0402
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Heart Left Ventricle | KIF2A | 0.12 | 0.00 | lasso | 4 | -0.01 | 0.8760 | -3.1 | 5.3 | 1.2e-07 | 0.42 | 0.05 | 0.60 | FALSE |
| 2 | METSIM | Adipose | KIF2A | 0.05 | 0.02 | lasso | 4 | 0.02 | 0.0011 | 5.3 | -5.4 | 5.3e-08 | -0.94 | 0.01 | 0.94 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | IPO11 | 0.03 | 0.00 | blup | 127 | 0.01 | 0.0297 | 3.6 | 5.5 | 4.0e-08 | 0.71 | 0.03 | 0.29 | TRUE |
| 4 | The Cancer Genome Atlas | Soft Tissue Sarcoma | IPO11 | 0.08 | 0.01 | lasso | 5 | 0.04 | 0.0013 | 5.3 | 5.2 | 2.7e-07 | 0.91 | 0.01 | 0.80 | FALSE |