Best TWAS P=8.76e-13 · Best GWAS P=1.24e-16 conditioned to 5.16e-14
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | NSUN6 | 0.18 | 0.11 | lasso | 8 | 0.10 | 4.9e-08 | -3.6 | 5.6 | 1.7e-08 | -0.14 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Esophagus Gastroesophageal Junction | NSUN6 | 0.22 | 0.03 | lasso | 7 | 0.03 | 3.1e-02 | -3.5 | 5.1 | 3.1e-07 | -0.11 | 0.20 | 0.10 | TRUE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CACNB2 | 0.05 | 0.05 | enet | 4 | 0.04 | 8.8e-06 | 6.0 | 7.2 | 8.8e-13 | -0.03 | 0.98 | 0.01 | TRUE |