Hub : Genes

NSUN6

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1030 0.0270 1.5e-07 0.090 0.048 0.076 0.063 0.090 4.8e-11 1.4e-06 1.3e-09 4.3e-08 4.4e-11
2 GTEx Adipose Subcutaneous 0.2290 0.0440 1.1e-11 0.241 NA 0.217 NA 0.235 1.1e-19 NA 1.2e-17 NA 3.7e-19
3 GTEx Adipose Visceral Omentum 0.1380 0.0500 2.4e-03 0.077 NA 0.081 NA 0.077 8.4e-05 NA 5.2e-05 NA 8.4e-05
4 GTEx Adrenal Gland 0.1816 0.0648 3.9e-03 0.070 NA -0.007 NA 0.078 1.7e-03 NA 7.6e-01 NA 9.4e-04
5 GTEx Artery Aorta 0.2440 0.0550 4.0e-08 0.227 NA 0.207 NA 0.219 1.0e-12 NA 1.3e-11 NA 2.8e-12
6 GTEx Artery Tibial 0.1802 0.0443 5.1e-07 0.113 NA 0.092 NA 0.097 4.0e-09 NA 1.2e-07 NA 4.9e-08
7 GTEx Brain Caudate basal ganglia 0.2920 0.0850 3.7e-04 0.215 NA 0.210 NA 0.219 8.0e-07 NA 1.1e-06 NA 6.4e-07
8 GTEx Brain Cerebellum 0.4690 0.1010 1.9e-04 0.144 NA 0.149 NA 0.228 5.0e-05 NA 3.6e-05 NA 2.3e-07
9 GTEx Brain Frontal Cortex BA9 0.3910 0.1204 2.2e-03 0.035 NA 0.082 NA 0.089 4.3e-02 NA 3.4e-03 NA 2.4e-03
10 GTEx Brain Nucleus accumbens basal ganglia 0.2530 0.0990 9.5e-03 0.139 NA 0.080 NA 0.163 1.5e-04 NA 3.6e-03 NA 4.0e-05
11 GTEx Brain Putamen basal ganglia 0.5310 0.1190 7.8e-04 0.107 NA 0.221 NA 0.107 1.6e-03 NA 5.6e-06 NA 1.7e-03
12 GTEx Breast Mammary Tissue 0.3170 0.0640 4.4e-08 0.146 NA 0.175 NA 0.197 6.1e-08 NA 2.5e-09 NA 2.2e-10
13 GTEx Colon Sigmoid 0.2710 0.1000 5.4e-03 0.142 NA 0.134 NA 0.139 1.0e-05 NA 1.9e-05 NA 1.3e-05
14 GTEx Esophagus Gastroesophageal Junction 0.2190 0.0770 8.5e-04 0.032 NA 0.018 NA 0.029 2.6e-02 NA 7.1e-02 NA 3.1e-02
15 GTEx Esophagus Mucosa 0.2090 0.0550 4.4e-06 0.107 NA 0.115 NA 0.142 1.2e-07 NA 4.4e-08 NA 9.6e-10
16 GTEx Esophagus Muscularis 0.2210 0.0560 4.5e-06 0.042 NA 0.092 NA 0.080 1.4e-03 NA 3.3e-06 NA 1.3e-05
17 GTEx Heart Atrial Appendage 0.1620 0.0620 2.3e-03 -0.003 NA -0.006 NA 0.014 4.4e-01 NA 8.4e-01 NA 7.2e-02
18 GTEx Lung 0.3207 0.0558 3.4e-13 0.147 NA 0.196 NA 0.221 2.2e-11 NA 6.3e-15 NA 7.4e-17
19 GTEx Nerve Tibial 0.3717 0.0531 0.0e+00 0.354 NA 0.359 NA 0.183 4.9e-26 NA 1.7e-26 NA 5.7e-13
20 GTEx Pancreas 0.2130 0.0790 6.8e-03 0.128 NA 0.128 NA 0.141 4.6e-06 NA 4.8e-06 NA 1.5e-06
21 GTEx Skin Not Sun Exposed Suprapubic 0.1400 0.0460 2.8e-04 0.100 NA 0.091 NA 0.079 3.9e-06 NA 1.0e-05 NA 3.9e-05
22 GTEx Skin Sun Exposed Lower leg 0.0750 0.0310 7.6e-03 0.023 NA 0.027 NA 0.023 4.5e-03 NA 2.4e-03 NA 4.4e-03
23 GTEx Spleen 0.4180 0.0990 5.7e-05 0.310 NA 0.298 NA 0.008 1.0e-08 NA 2.3e-08 NA 1.9e-01
24 GTEx Thyroid 0.1320 0.0390 2.7e-05 0.107 NA 0.115 NA 0.119 1.5e-08 NA 4.4e-09 NA 2.1e-09
25 GTEx Whole Blood 0.0580 0.0240 5.3e-03 0.041 NA 0.026 NA 0.037 1.0e-04 NA 1.6e-03 NA 2.4e-04
26 METSIM Adipose 0.1752 0.0307 0.0e+00 0.228 0.203 0.228 0.215 0.215 1.2e-33 1.1e-29 1.3e-33 1.7e-31 1.4e-31
27 NTR Blood 0.0592 0.0134 1.5e-12 0.051 0.043 0.048 0.045 0.049 5.7e-16 1.0e-13 3.5e-15 1.8e-14 2.1e-15
28 ROSMAP Brain Pre-frontal Cortex 0.2264 0.0392 0.0e+00 0.229 0.168 0.219 0.212 0.223 4.9e-29 4.8e-21 1.3e-27 9.8e-27 3.8e-28
29 YFS Blood 0.0688 0.0146 0.0e+00 0.073 0.073 0.081 0.079 0.077 8.0e-23 6.8e-23 2.8e-25 1.2e-24 7.7e-24
30 TCGA Bladder Urothelial Carcinoma 0.0570 0.0310 1.4e-03 0.012 0.035 0.009 NA 0.009 2.9e-02 5.4e-04 5.4e-02 NA 5.1e-02
31 TCGA Breast Invasive Carcinoma 0.1014 0.0286 1.8e-14 0.053 0.073 0.088 NA 0.082 4.6e-11 9.9e-15 1.9e-17 NA 2.2e-16
32 TCGA Cervical Squamous Cell Carcinoma 0.1750 0.0670 8.4e-04 0.046 0.046 0.062 NA 0.037 2.6e-03 2.5e-03 5.2e-04 NA 6.4e-03
33 TCGA Colon Adenocarcinoma 0.0820 0.0420 1.5e-03 0.012 0.052 0.015 NA 0.004 6.0e-02 5.6e-04 4.5e-02 NA 1.9e-01
34 TCGA Glioblastoma Multiforme 0.2370 0.0910 1.4e-05 0.117 0.143 0.159 NA 0.134 2.2e-04 4.2e-05 1.5e-05 NA 7.2e-05
35 TCGA Head and Neck Squamous Cell Carcinoma 0.0649 0.0295 1.1e-03 0.047 0.026 0.034 NA 0.035 5.0e-06 6.3e-04 1.0e-04 NA 7.3e-05
36 TCGA Kidney Renal Clear Cell Carcinoma 0.0961 0.0359 2.5e-07 0.049 0.057 0.060 NA 0.061 3.3e-06 5.4e-07 2.4e-07 NA 2.1e-07
37 TCGA Kidney Renal Papillary Cell Carcinoma 0.1100 0.0460 1.0e-04 0.109 0.065 0.065 NA 0.072 8.2e-07 1.4e-04 1.4e-04 NA 5.8e-05
38 TCGA Brain Lower Grade Glioma 0.1382 0.0453 4.9e-15 0.152 0.128 0.131 NA 0.139 7.0e-17 2.5e-14 1.2e-14 NA 1.5e-15
39 TCGA Lung Adenocarcinoma 0.1088 0.0463 8.9e-07 0.040 0.070 0.051 NA 0.046 1.6e-05 1.3e-08 1.3e-06 NA 3.9e-06
40 TCGA Lung Squamous Cell Carcinoma 0.0344 0.0190 1.9e-03 0.017 0.014 0.012 NA 0.017 4.4e-03 9.7e-03 1.6e-02 NA 4.0e-03
41 TCGA Prostate Adenocarcinoma 0.1550 0.0466 1.3e-09 0.127 0.079 0.123 NA 0.117 3.4e-13 1.3e-08 9.0e-13 NA 2.9e-12
42 TCGA Thyroid Carcinoma 0.1420 0.0450 3.0e-09 0.114 0.077 0.070 NA 0.083 3.6e-11 6.0e-08 2.4e-07 NA 1.9e-08

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42
Bipolar Disorder (2018) 1.7 2.7 13.3 -1.9 -1.2 -1.3 -2.4 -1.7 -1.9 -1.0 -0.9 -0.5 -1.7 -0.5 -0.9 -1.0 -3.6 -1.6 -0.9 1.2 -1.7 -1.2 -0.7 -2.1 -1.0 -1.1 -0.8 -1.1 -1.3 -0.8 -1.1 -0.9 -2.0 -1.7 -0.9 -1.8 -1.2 -2.6 -2.3 -2.5 -0.9 -2.1 -2.2 -2.7 -1.8
Bipolar Disorder or Schizophrenia 1.6 3.9 22.9 -3.6 -1.1 -1.0 -1.0 -2.7 -2.8 -1.0 0.5 -2.0 -2.2 -1.0 0.4 -0.8 -4.8 -1.0 0.5 1.3 -0.3 -0.9 1.3 -1.8 -0.2 -0.3 -0.1 -1.2 -1.2 -0.2 -0.8 -0.4 -3.6 -1.5 -2.6 -2.8 -0.1 -2.6 -2.8 -2.7 -0.8 -3.4 -3.0 -2.6 -2.9
Depressed Affect (Nagel 2018) 0.1 0.2 1.7 0.4 0.4 -0.1 0.6 -0.1 -0.5 0.4 -0.4 -0.0 1.3 -0.4 -0.3 0.4 -0.0 0.3 0.8 -0.2 -0.1 -0.3 -0.4 -0.2 0.0 -0.1 -0.2 0.1 0.3 -0.2 0.1 0.4 1.3 0.0 -0.2 0.4 -0.3 0.3 0.0 0.2 0.0 0.1 0.2 0.5 -0.0
Depression (Nagel 2018) 0.4 0.6 3.1 -1.0 -0.6 -0.9 0.3 -1.2 -1.4 -0.6 -0.2 -0.3 -0.6 -0.7 -0.6 -0.4 -1.8 -0.3 0.3 0.7 -0.5 -0.7 -0.2 -0.7 -0.6 -0.5 -0.7 -0.9 -0.6 -0.6 -0.6 -0.4 -0.8 -0.8 -0.4 -1.0 -0.4 -0.8 -1.0 -0.9 -0.7 -0.9 -1.0 -0.6 -1.2
Intelligence (Savage-Jansen 2018) 0.7 2.2 9.6 1.4 1.8 1.4 0.1 1.3 1.4 1.9 0.3 3.1 2.5 2.6 0.9 1.8 0.3 1.0 0.6 -2.1 0.9 1.0 0.6 1.3 1.4 1.5 1.2 1.5 1.7 1.3 1.5 1.5 1.9 1.1 -0.2 2.8 1.5 0.3 0.9 0.5 1.6 1.1 1.6 0.7 1.3
Neuroticism (Nagel 2018) 0.3 0.7 3.6 1.0 1.1 0.2 1.5 0.5 0.3 0.9 -0.1 0.0 1.6 -0.2 -0.2 1.0 0.2 1.1 0.7 -1.0 0.3 0.3 -0.3 0.7 0.5 0.3 -0.0 0.5 1.0 0.1 0.7 1.2 1.9 0.8 -0.1 1.9 0.4 1.0 0.6 0.8 0.4 0.4 1.0 1.3 0.3
Schizophrenia (2018) 1.1 2.4 10.3 -3.1 -0.5 -0.3 0.5 -2.1 -2.1 -0.4 1.4 -2.7 -1.4 -0.9 1.3 -0.2 -3.2 0.0 1.3 0.7 0.9 -0.2 2.3 -0.7 0.5 0.5 0.5 -0.6 -0.5 0.4 -0.2 0.3 -3.0 -0.6 -2.6 -2.1 0.8 -1.2 -1.7 -1.5 -0.2 -2.6 -2.1 -1.2 -2.3
Schizophrenia vs Biploar Disorder 2.5 3.3 7.9 1.7 1.4 1.6 2.6 1.4 2.0 1.4 2.2 1.3 2.0 1.9 2.1 1.2 1.6 2.0 1.9 -1.5 2.4 1.6 2.2 2.7 1.8 1.9 1.6 1.4 1.8 1.5 1.5 2.4 0.7 2.1 0.7 1.5 2.8 2.0 1.9 2.0 1.4 1.7 1.8 2.0 1.4
Worry (Nagel 2018) 0.5 1.1 4.4 1.2 1.6 0.7 1.0 0.7 0.4 1.6 -0.2 0.5 1.1 -0.4 0.3 1.7 0.8 1.1 0.8 -1.8 0.5 0.9 -0.1 0.9 1.0 0.8 0.7 1.2 1.6 0.8 1.2 1.7 1.8 0.9 -0.2 2.1 0.7 0.8 0.7 0.7 1.2 0.8 1.1 0.9 0.6
Alzheimer’s Disease (in mother) 3.9 4.5 8.4 -1.9 -1.9 -2.2 -2.5 -2.0 -1.8 -1.7 -2.8 -2.0 -1.7 -2.3 -2.9 -1.2 -1.4 -2.5 -2.8 1.5 -2.6 -1.2 -2.6 -2.4 -2.2 -2.2 -2.0 -1.5 -1.8 -2.0 -1.9 -1.7 -2.1 -2.1 -1.3 -0.1 -2.0 -2.5 -2.8 -2.7 -1.8 -2.6 -2.4 -2.4 -2.2
Alzheimer’s Disease (in father) 0.4 0.5 3.6 0.6 0.8 0.3 -0.6 0.6 0.5 0.8 -0.2 0.1 0.8 0.8 0.2 0.6 1.9 0.2 0.3 -1.0 0.0 0.6 -0.2 1.0 0.3 0.6 0.4 1.0 0.9 0.5 0.6 0.6 0.4 -0.3 -0.6 1.5 0.4 -0.7 -0.2 -0.6 0.7 1.0 0.2 -0.6 0.3
Alzheimer’s Disease (including proxy) 4.3 6.3 11.0 -2.1 -2.3 -2.7 -2.8 -2.3 -2.4 -2.3 -3.3 -2.4 -2.3 -2.2 -3.3 -1.9 -1.0 -2.8 -3.1 2.1 -3.2 -1.8 -3.2 -2.5 -2.9 -2.8 -2.7 -2.0 -2.3 -2.6 -2.4 -2.3 -2.2 -2.7 -1.1 -0.4 -2.7 -2.9 -3.0 -3.0 -2.3 -2.1 -2.7 -2.6 -2.4
Crohns Disease (2017) 0.4 0.8 4.3 0.2 -0.8 -0.5 -1.6 -0.3 -0.4 -0.7 -0.9 -1.2 -1.1 -2.0 -0.2 -0.7 0.1 -1.3 -0.5 0.4 -1.1 -0.3 -0.7 -0.3 -0.6 -0.6 -0.4 -0.5 -0.7 -0.4 -0.8 -1.1 -1.3 -0.9 -0.6 -0.7 -0.2 -1.8 -1.0 -1.6 -0.5 -0.3 -0.7 -2.1 -0.5
Irritable Bowel Disease (IBD) 0.1 0.2 1.0 0.3 0.1 0.2 0.5 -0.1 0.1 0.2 0.5 -0.8 -0.7 -0.6 0.9 0.1 0.8 0.1 0.4 -0.3 0.4 0.5 0.7 0.8 0.4 0.3 0.5 0.3 0.2 0.4 0.2 0.3 -0.9 0.4 -0.9 -0.1 1.0 -0.1 0.1 -0.1 0.3 -0.5 -0.0 -0.6 -0.2
Ulcerative Colitis (UC) 0.2 0.4 2.8 0.1 0.4 0.2 1.7 -0.2 0.3 0.6 0.9 -0.4 -0.5 0.4 0.8 0.4 0.5 0.8 0.3 -0.5 0.8 0.5 1.1 0.9 0.6 0.5 0.5 0.5 0.4 0.4 0.6 0.9 -0.3 0.9 -0.9 0.3 0.9 1.0 0.6 0.8 0.5 -0.7 0.2 0.5 -0.1
Major Depression (MDD) 0.2 0.3 1.1 -0.5 0.1 0.1 -0.5 -0.6 -0.4 0.3 0.3 -0.2 -0.2 0.9 0.7 0.0 -1.0 -0.2 0.9 -0.4 0.2 0.2 0.7 0.5 0.5 0.3 0.4 0.1 0.4 0.3 0.2 0.7 -1.1 0.1 -0.3 -0.5 0.7 -0.5 -0.4 -0.5 0.3 -0.6 -0.2 -0.8 -0.6
Reaction Time 0.5 0.9 4.9 -0.3 -0.6 -1.0 -0.0 -0.5 -0.5 -0.5 -1.7 -0.9 -1.4 -0.2 -2.2 -0.7 -0.4 -0.6 -0.9 0.8 -1.4 -0.8 -1.8 -1.3 -1.2 -1.3 -1.3 -0.5 -0.7 -1.1 -0.6 -0.3 0.4 -0.6 -0.5 0.8 -1.8 -0.1 -0.6 -0.3 -0.7 -0.5 -0.7 0.2 -0.4
Verbal and Numeric Reasoning (VNR) 0.7 1.8 7.9 1.5 1.4 1.2 -0.1 1.5 1.5 1.5 0.0 2.5 2.8 2.3 0.5 1.3 0.7 0.7 0.6 -2.0 0.6 0.9 0.1 1.2 1.1 1.1 0.9 1.3 1.5 1.0 1.2 0.9 1.7 1.0 0.3 2.8 1.3 0.1 0.8 0.5 1.2 1.1 1.6 0.6 1.5
Breast Cancer 0.2 0.4 1.4 -0.6 -0.4 -1.1 -0.1 -0.8 -0.4 -0.5 -1.0 -0.6 -0.6 0.1 -0.9 -0.4 -0.7 -0.4 -1.2 0.4 -0.6 -0.6 -0.7 -0.4 -0.7 -0.7 -1.0 -0.6 -0.4 -0.9 -0.7 -0.4 -0.2 -0.7 0.0 0.1 -0.8 0.6 -0.3 0.2 -0.7 -0.3 -0.5 0.3 -0.8
Ovarian Cancer 0.4 0.5 4.4 1.3 0.1 -0.1 1.4 0.2 0.8 -0.1 0.2 0.7 1.0 0.1 0.0 0.1 0.1 0.7 0.0 0.0 0.2 -0.3 -0.2 0.3 -0.4 -0.5 -0.4 -0.4 -0.1 -0.3 -0.0 0.7 0.3 1.2 2.1 0.7 0.6 1.3 1.0 1.2 -0.2 0.7 0.8 1.3 0.6
Prostate Cancer 0.9 1.2 2.6 1.5 1.1 1.6 -0.1 1.6 1.1 1.3 0.6 1.0 0.8 0.2 1.1 1.3 0.2 0.4 1.0 -1.3 0.6 1.3 0.9 0.7 1.2 1.2 1.6 1.5 1.2 1.5 1.3 0.8 1.0 1.1 0.6 1.1 0.9 0.4 1.2 0.7 1.5 1.4 1.3 0.6 1.4
Age at First Birth 0.9 1.3 4.2 0.3 1.4 1.1 0.5 0.6 0.7 1.5 1.3 1.5 0.8 0.6 1.3 1.5 1.4 1.3 0.9 -1.5 1.5 1.0 1.3 0.7 1.3 1.4 1.5 1.4 1.2 1.4 1.3 1.1 0.9 0.9 -2.0 0.8 1.4 0.5 0.6 0.6 1.5 -0.8 0.6 0.6 0.5
Bipolar Disorder (2011) 6.7 6.5 14.0 -2.9 -2.3 -2.0 -3.3 -2.3 -2.6 -2.2 -2.2 -2.1 -3.2 -1.6 -2.2 -2.1 -3.7 -2.7 -1.5 2.5 -2.7 -1.9 -2.0 -3.7 -2.1 -2.1 -1.8 -2.1 -2.5 -1.9 -2.1 -2.6 -1.8 -2.9 -1.7 -3.3 -2.9 -3.2 -3.1 -3.2 -2.0 -2.7 -3.1 -3.0 -2.4
Body Mass Index (BMI) (2010) 1.0 1.4 3.0 -0.5 -1.5 -1.1 -0.8 -0.7 -0.7 -1.7 -0.9 -1.5 -1.2 -1.2 -1.4 -1.6 -1.3 -1.0 -1.7 1.7 -0.9 -1.4 -1.3 -1.3 -1.7 -1.4 -1.3 -1.5 -1.5 -1.3 -1.3 -1.7 -0.8 -0.8 0.9 -1.1 -1.0 -0.9 -0.8 -0.9 -1.4 -0.4 -0.7 -0.7 -0.6
Coronary Artery Disease (CAD) 0.9 1.0 3.4 1.5 1.6 0.7 0.6 1.4 1.5 1.0 -0.1 0.0 0.8 0.7 0.5 1.2 1.1 1.0 -0.0 -1.1 0.5 1.1 0.2 0.9 0.7 0.8 0.5 1.4 1.2 0.8 1.0 1.2 1.7 0.8 0.6 1.8 0.6 0.5 0.8 0.6 1.1 1.4 1.0 0.8 1.1
Crohns Disease (2012) 0.2 0.3 2.2 0.7 -0.4 -0.3 -0.3 0.2 0.1 -0.3 -0.3 -0.5 -0.5 -1.5 -0.2 -0.5 0.3 -0.7 -0.2 0.1 -0.7 -0.1 -0.5 -0.4 -0.4 -0.5 -0.3 -0.1 -0.4 -0.2 -0.4 -0.4 -0.7 -0.2 0.6 -0.3 -0.2 -1.1 -0.4 -0.9 -0.2 0.4 -0.2 -1.2 0.1
Mean Putamen Volume 0.2 0.2 1.2 0.2 -0.1 0.3 1.1 0.5 0.7 0.1 0.7 -0.8 0.7 -0.1 -0.0 -0.0 0.2 0.4 0.9 0.0 0.2 0.1 0.4 0.4 0.1 0.2 0.3 0.2 0.2 0.3 0.3 0.2 0.3 0.9 0.3 -0.4 0.4 0.4 0.4 0.4 0.2 0.2 0.5 0.5 0.4
Fasting Glucose 1.1 1.3 6.2 1.1 1.1 1.5 0.4 1.0 0.7 1.3 1.1 -1.3 2.5 0.7 1.5 1.0 1.2 0.9 1.4 -1.0 1.5 1.2 1.4 1.4 1.4 1.3 1.6 1.0 1.1 1.3 1.4 0.9 0.1 0.4 -0.5 1.4 1.4 0.1 0.3 0.1 1.2 0.4 1.0 0.1 -0.7
HbA1C 0.4 0.4 2.9 1.1 0.2 0.7 0.6 1.0 0.5 0.2 0.7 -0.5 0.8 1.1 0.3 0.2 0.2 0.4 0.7 -0.2 0.3 0.4 0.8 0.3 0.1 0.4 0.4 0.3 0.4 0.5 0.5 0.5 -0.1 0.7 1.7 0.9 0.9 0.8 0.7 0.7 0.4 0.5 1.0 0.7 -0.7
HDL Cholesterol 0.6 0.9 4.8 -0.4 1.3 0.4 0.6 0.0 0.7 1.5 0.3 0.9 0.4 1.2 0.7 1.1 0.8 0.9 0.5 -1.4 0.9 1.3 0.5 1.2 1.3 1.1 0.8 1.4 1.4 0.8 1.1 2.2 0.5 0.6 -2.2 1.0 0.7 0.4 -0.0 0.2 1.1 -0.4 0.2 0.0 -0.4
LDL Cholesterol 0.4 0.7 2.9 0.9 0.8 0.9 -0.2 0.9 0.2 0.6 0.4 0.7 -0.0 0.6 0.9 0.6 1.6 0.4 0.4 -0.8 0.8 0.5 0.8 0.7 0.8 0.9 0.8 0.5 0.8 0.8 0.7 -0.1 1.5 1.1 0.7 -0.2 0.5 0.7 1.0 0.9 0.8 1.7 1.1 0.8 1.1
Lupus 1.1 1.7 5.6 1.6 1.9 1.4 1.0 1.6 1.1 1.9 0.6 0.5 1.0 0.3 0.3 2.2 1.1 1.4 0.9 -1.8 0.7 1.0 0.0 0.5 1.3 0.9 1.3 2.0 1.6 1.4 1.9 1.4 2.4 1.3 0.2 1.3 0.0 0.3 0.9 0.6 1.9 1.5 1.3 0.9 1.5
Neuroticism (2016) 0.2 0.3 1.8 0.7 0.3 0.4 0.2 0.3 -0.2 0.5 0.0 -1.2 1.3 0.5 0.1 0.5 0.5 0.0 0.6 -0.7 -0.2 0.4 0.1 0.3 0.5 0.5 0.3 0.4 0.9 0.4 0.4 0.7 0.6 0.2 -0.3 1.0 0.6 0.3 0.4 0.3 0.4 0.1 0.3 -0.1 0.1
Primary Biliary Cirrhosis 0.3 0.5 2.4 -1.2 -0.3 -0.5 -0.3 -1.1 -1.0 -0.3 -0.2 -0.3 -0.7 -0.4 0.3 -0.4 -1.3 -0.4 -0.3 0.3 0.0 -0.1 0.5 0.1 0.0 -0.2 -0.1 -0.2 -0.5 -0.2 -0.4 0.3 -1.4 -0.2 -1.2 -0.9 0.1 -0.3 -0.9 -0.6 -0.4 -1.6 -0.8 -0.9 -1.3
Rheumatoid Arthritis 0.6 0.8 3.1 -1.7 -0.9 -1.0 0.1 -1.0 -1.0 -0.9 -0.4 -0.7 -1.7 -0.5 -0.9 -0.7 0.0 -0.6 -0.5 1.0 -0.4 -0.6 -0.3 -0.7 -0.8 -0.9 -0.8 -0.6 -1.0 -0.8 -0.8 -0.8 -0.9 -0.5 -1.1 -0.9 -0.9 -0.2 -1.0 -0.5 -0.9 -1.7 -1.3 -0.3 -1.3
Schizophrenia (2014) 1.5 3.2 18.5 -3.3 -1.2 -1.0 -0.1 -2.6 -2.7 -1.1 0.9 -2.4 -2.4 -0.8 0.6 -1.0 -4.3 -0.6 0.1 1.4 0.2 -1.0 1.6 -1.3 -0.3 -0.2 -0.1 -1.2 -1.1 -0.3 -0.9 -0.4 -3.4 -1.0 -2.4 -2.8 0.3 -1.4 -2.1 -1.8 -0.9 -3.0 -2.6 -1.5 -2.8
Triglycerides 0.4 0.6 3.6 0.0 -0.8 -0.5 -0.1 -0.1 -0.2 -1.1 -0.6 -0.9 -0.8 -0.9 -0.9 -0.5 -1.0 -0.5 -1.1 1.0 -0.7 -0.7 -0.6 -1.4 -1.2 -1.0 -0.8 -0.8 -1.0 -0.7 -0.6 -1.2 -0.1 -0.3 1.9 -0.6 -1.2 0.0 0.0 0.1 -0.7 0.6 -0.0 0.2 0.2
Type 2 Diabetes (T2D) (2012) 0.9 1.0 2.5 -1.0 -1.5 -0.8 -0.6 -1.2 -1.1 -1.5 -0.3 -1.5 -1.2 0.1 -0.4 -1.4 -0.3 -1.1 -1.1 1.2 -0.6 -1.3 -0.1 -0.9 -0.9 -0.7 -1.0 -1.6 -1.0 -1.0 -1.2 -1.4 -1.1 -0.6 -0.4 -1.5 -0.3 -0.5 -0.7 -0.6 -1.3 -0.9 -1.1 -0.8 -0.9
Ulcerative Colitis 0.3 0.4 1.1 -0.7 -0.8 -1.0 0.9 -1.1 -0.4 -0.5 -0.2 -1.1 -0.6 0.3 -0.6 -0.6 -0.7 -0.1 -0.8 0.7 -0.3 -0.9 -0.2 -0.2 -0.6 -0.8 -0.8 -0.8 -0.6 -0.8 -0.6 0.0 -1.0 0.2 0.0 -0.5 -0.2 0.5 -0.3 0.1 -0.8 -0.9 -0.5 -0.0 -0.8
Blood Eosinophil Count 0.3 2.3 4.6 0.6 1.9 1.6 1.1 1.1 1.0 1.9 1.9 0.3 0.4 1.1 1.9 2.0 1.1 2.0 1.9 -1.8 2.1 1.6 1.6 1.7 2.0 2.0 1.9 1.7 1.9 1.9 1.9 1.8 1.3 1.1 -0.5 0.9 1.6 0.8 1.1 0.9 1.8 1.1 1.1 1.0 1.1
Blood Platelet Count 0.6 7.2 12.7 1.5 3.4 2.4 3.2 1.5 1.6 3.3 2.5 0.9 2.2 1.8 3.0 3.4 1.6 3.4 3.2 -3.1 2.9 2.8 3.0 2.4 3.6 2.9 2.8 2.8 3.2 2.8 3.1 3.4 2.1 3.0 -0.6 2.8 2.3 3.1 2.5 2.9 3.0 2.2 2.3 2.7 1.6
Blood Red Count 0.1 0.6 2.7 0.3 0.2 0.9 -0.6 0.2 0.4 0.3 1.2 -0.4 0.4 -0.0 1.6 0.5 -0.7 0.4 1.1 -0.4 1.2 0.6 1.6 1.1 0.6 1.1 1.1 0.3 0.5 1.0 0.5 0.3 -0.9 0.5 0.5 -0.6 1.6 0.4 0.7 0.4 0.5 0.6 0.4 0.1 0.2
Blood White Count 0.5 3.8 8.9 1.8 1.7 2.2 1.5 1.9 1.9 1.6 2.4 1.0 1.1 0.6 2.6 1.6 1.8 1.9 2.1 -1.5 2.6 2.2 3.0 2.6 2.2 2.3 2.3 1.7 1.8 2.2 1.9 1.2 1.3 2.1 0.5 0.7 2.4 1.8 2.2 2.0 2.0 2.1 1.9 1.8 2.0
Heel T-Score 0.3 2.4 6.6 -0.2 -1.9 -1.5 -1.5 -0.6 -1.3 -1.6 -1.9 -0.7 -1.0 -1.9 -2.1 -1.7 -1.2 -2.1 -1.9 1.1 -2.6 -2.0 -2.0 -2.1 -1.8 -1.7 -1.6 -1.2 -1.4 -1.6 -1.7 -1.5 -1.3 -1.4 0.8 -0.7 -1.3 -1.8 -1.5 -1.6 -1.5 -0.3 -0.9 -1.6 -0.8
BMI 0.5 3.1 9.0 -1.7 -1.9 -1.9 -0.2 -1.9 -2.0 -2.2 -0.8 -2.1 -2.3 -2.9 -1.5 -1.8 -3.0 -1.0 -2.0 2.4 -1.4 -1.9 -1.3 -2.0 -1.6 -1.9 -2.0 -2.5 -2.0 -2.0 -2.0 -2.1 -1.0 -0.6 1.0 -2.6 -1.8 0.6 -0.7 0.1 -2.1 -0.6 -1.2 0.1 -1.3
Height 0.0 0.9 5.3 -0.7 0.8 -1.3 1.8 -0.9 0.5 0.5 -0.8 -1.4 0.0 -0.4 -0.6 0.6 -1.0 1.0 -1.0 -0.2 -0.1 0.1 -1.1 -0.8 -0.2 -0.7 -1.1 0.2 0.3 -0.9 -0.0 1.8 1.0 0.6 -0.8 0.6 -1.2 2.3 0.3 1.4 -0.3 0.4 0.2 1.3 -1.1
Waist Hip Ratio (WHR) 0.1 0.4 2.0 -0.8 -0.4 -0.1 -1.1 -0.7 -0.9 -0.3 -0.2 0.2 -0.2 0.5 -0.2 -0.4 -1.2 -0.5 0.2 0.7 -0.3 -0.7 -0.3 -0.5 -0.3 -0.2 0.0 -0.7 -0.6 -0.1 -0.3 -0.5 -0.0 -0.9 -1.1 -1.4 -0.6 -1.0 -0.8 -0.9 -0.3 -0.6 -1.0 -0.8 -0.6
Systolic Blood Pressure 7.7 38.5 104.0 6.7 7.0 6.5 2.0 7.8 10.2 6.9 3.4 7.3 6.3 2.6 5.0 6.5 9.6 4.7 3.5 -7.2 6.1 8.2 3.7 7.6 5.8 6.4 6.2 8.4 6.9 6.3 6.5 7.4 6.1 4.8 -1.0 8.0 6.7 2.4 4.9 3.5 6.8 4.3 6.2 2.8 6.2
Smoking Status 1.0 2.3 6.0 -2.4 -1.4 -1.4 -1.1 -2.5 -1.7 -1.3 -0.6 -2.2 -1.0 -0.8 -0.3 -1.3 -2.4 -1.4 -0.2 1.4 -0.8 -0.4 -0.2 -1.1 -0.8 -0.8 -0.9 -1.6 -1.2 -1.0 -1.4 -0.5 -2.3 -1.8 -2.3 -1.6 -0.7 -1.2 -1.9 -1.6 -1.3 -1.9 -2.2 -1.7 -2.4
Allergy or Eczema 0.5 1.3 3.6 0.6 1.5 1.1 1.0 0.7 0.3 1.4 0.8 1.0 1.2 1.9 1.1 1.3 0.5 1.2 1.5 -1.1 1.1 0.9 0.8 1.3 1.6 1.1 1.1 1.2 1.1 1.1 1.2 0.9 0.9 1.4 -0.8 1.4 1.1 1.4 1.1 1.3 1.2 0.2 1.1 1.2 0.7
Cardiovascular Disease 4.5 14.9 34.2 3.7 4.4 3.9 2.2 4.4 5.8 4.3 2.6 4.2 3.7 2.1 3.4 4.2 5.0 3.5 2.1 -4.3 4.2 5.6 2.8 4.4 3.7 3.9 3.9 5.2 4.3 4.0 4.2 4.5 3.6 3.3 -0.4 4.8 4.0 2.7 3.5 3.0 4.3 2.9 3.7 2.4 3.5
Hypothyroidism (self reported) 0.1 0.2 0.8 0.5 -0.5 0.0 -0.7 0.4 0.5 -0.6 -0.1 0.3 0.3 -0.8 -0.2 -0.6 0.8 -0.5 -0.1 0.4 -0.3 -0.1 -0.2 -0.5 -0.4 -0.2 -0.2 -0.4 -0.4 -0.2 -0.3 -0.9 0.2 -0.4 0.4 -0.0 -0.2 -0.3 0.2 -0.0 -0.3 0.8 0.2 -0.1 0.6
Respiratory disease 0.5 1.0 5.7 -1.4 -0.8 -1.0 -0.7 -1.9 -1.9 -0.6 -0.2 -1.4 0.6 0.3 -0.0 -0.5 -1.6 -0.7 -0.1 1.0 -0.5 -1.1 -0.1 -0.2 -0.3 -0.8 -0.6 -0.9 -0.9 -0.6 -0.8 -0.5 -2.4 -1.2 -0.8 -0.6 -0.3 -0.8 -1.3 -1.1 -0.8 -0.7 -1.7 -1.0 -1.9
Type 2 Diabetes (T2D) (2018) 0.4 0.8 2.2 1.2 0.8 1.4 -0.4 1.4 0.7 0.7 0.4 -0.4 0.8 -1.2 0.8 0.8 1.0 0.3 0.5 -0.8 0.6 0.7 0.7 0.5 0.8 1.1 1.1 1.1 0.9 1.1 0.9 0.5 1.4 0.6 0.4 0.0 0.6 -0.0 0.8 0.4 1.1 1.5 1.1 -0.1 1.3
Lung FEV1/FVC ratio 0.6 2.8 10.1 -0.3 -2.5 -1.2 -0.2 -1.4 -2.4 -2.3 0.4 -1.1 -1.1 -0.6 -0.6 -2.1 -3.0 -1.1 -0.4 2.6 -1.2 -2.8 -0.2 -1.6 -1.8 -1.6 -1.5 -2.9 -2.2 -1.6 -2.0 -1.6 -2.1 -0.2 3.2 -3.0 -0.8 0.3 -0.1 0.2 -2.1 -0.9 -0.8 0.0 -0.5
Lung FVC 0.3 1.3 3.9 1.4 0.8 1.3 0.4 1.2 1.4 0.9 1.3 1.5 1.3 0.2 1.3 1.1 1.4 1.1 0.8 -1.2 1.0 1.5 1.3 1.0 0.8 1.4 1.2 1.0 1.3 1.2 1.1 0.9 0.4 1.1 1.3 1.1 2.0 0.3 1.0 0.6 1.1 1.6 1.2 0.5 1.2
Neuroticism 0.4 1.0 5.3 1.6 0.8 0.1 1.8 0.5 0.4 0.7 0.1 -0.1 1.8 -0.2 -0.2 0.7 0.1 1.2 0.1 -0.9 -0.0 -0.3 -0.6 0.6 0.2 0.0 -0.3 0.3 1.0 -0.1 0.5 1.4 2.3 1.1 1.2 1.4 0.4 1.5 1.2 1.4 0.3 1.4 1.3 1.9 0.8
Chronotype (morning person) 0.1 0.2 1.9 -0.0 -0.2 -0.4 -0.0 -0.1 -0.1 -0.4 -0.3 -0.1 -0.5 -0.2 0.0 -0.2 -1.4 -0.3 -0.2 0.1 -0.5 -0.6 -0.2 0.3 -0.1 -0.3 -0.4 -0.3 -0.2 -0.3 -0.4 -0.5 -0.0 -0.1 0.7 -0.3 -0.4 0.6 0.4 0.5 -0.3 0.9 -0.0 0.1 0.0
Hair Pigment 0.0 1.4 5.4 1.6 1.0 1.4 -0.0 1.6 1.2 1.2 0.8 2.3 1.4 1.2 1.2 1.1 1.0 0.5 0.5 -1.3 1.1 1.4 1.0 0.6 0.8 1.1 1.3 1.3 1.3 1.3 1.1 0.5 1.1 0.9 0.9 0.9 1.0 0.6 1.3 0.9 1.3 1.8 1.4 0.5 1.5
Tanning 0.1 1.6 5.6 1.3 1.5 0.8 1.5 0.9 1.2 1.3 0.8 0.5 0.9 0.7 1.0 1.2 0.6 1.8 1.5 -1.1 1.0 1.1 0.6 1.4 1.1 0.8 0.7 1.3 1.1 0.9 1.2 2.0 0.4 1.6 0.7 2.4 1.4 1.9 1.4 1.7 1.1 1.0 1.3 1.7 0.9
Hand grip strength (left) 0.2 0.6 3.0 0.8 0.7 -0.0 -1.0 0.7 1.1 0.6 -1.6 0.5 0.5 -0.4 -1.1 0.5 1.7 -0.2 -0.7 -0.8 -0.8 0.5 -1.7 -0.3 -0.5 -0.1 -0.3 0.7 0.6 -0.1 0.3 0.6 1.4 -0.4 -0.5 1.7 -0.8 -0.3 -0.1 -0.2 0.3 1.0 0.5 -0.1 0.5
Number of treatments/medications taken 0.5 0.9 3.3 1.8 0.4 1.0 -1.3 1.4 1.6 0.6 -0.3 0.1 1.0 -0.8 0.5 0.5 1.8 -0.6 0.3 -1.0 0.2 1.6 0.1 0.9 0.6 0.8 1.0 1.3 0.8 1.0 0.7 0.0 0.5 -0.2 0.3 0.5 0.8 -1.4 0.1 -0.9 1.0 1.1 0.6 -1.4 0.9
Average weekly spirits intake 0.4 0.5 3.2 1.1 -0.3 -0.3 -0.0 0.7 1.0 -0.2 -1.0 -0.2 -0.1 -0.8 -1.4 -0.3 1.0 -0.2 -0.5 0.4 -1.0 -0.2 -1.8 -0.9 -0.8 -0.7 -0.8 -0.1 -0.3 -0.7 -0.3 -0.3 1.3 -0.0 1.0 0.5 -1.2 0.0 0.3 0.2 -0.3 0.9 0.4 0.4 0.9
Sensitivity / hurt feelings 0.7 1.2 4.3 -0.7 -0.9 -1.5 0.8 -1.3 -1.3 -1.0 -1.1 -2.1 -1.0 -2.0 -1.4 -0.7 -0.8 -0.5 -1.4 1.0 -1.4 -1.3 -1.4 -1.1 -1.1 -1.5 -1.6 -1.1 -1.0 -1.5 -1.1 0.0 -0.5 -0.5 -0.4 -0.3 -1.2 -0.1 -0.9 -0.5 -1.3 -1.2 -0.9 -0.2 -1.2
Frequency of depressed mood in last 2 weeks 0.2 0.3 1.2 -0.6 -0.5 -0.7 0.9 -0.6 -0.8 -0.3 0.3 -0.1 -0.4 -1.1 -0.5 -0.3 -1.1 0.2 0.3 0.4 -0.2 -0.6 -0.0 -0.8 -0.4 -0.5 -0.5 -0.5 -0.3 -0.5 -0.2 -0.1 0.0 0.0 0.1 -0.5 -0.3 0.6 -0.1 0.3 -0.4 -0.4 -0.2 0.7 -0.5
Hearing difficulty/problems: Yes 0.2 0.3 1.3 0.5 -0.1 0.1 0.9 0.4 0.2 -0.3 0.8 -0.6 0.1 -0.3 0.2 -0.4 -0.7 0.7 0.3 0.1 0.3 -0.1 0.3 -0.0 0.1 0.2 -0.1 -0.3 0.1 -0.1 -0.0 -0.0 0.2 0.9 1.1 0.0 0.6 1.0 0.8 1.0 -0.2 0.7 0.8 1.1 0.5
Relative age of first facial hair 0.2 0.4 2.5 0.9 0.1 0.2 0.0 0.8 0.5 0.1 -0.4 1.6 0.5 -0.2 -0.6 0.1 1.6 0.1 -0.2 0.1 -0.2 -0.3 -0.8 -0.2 -0.4 -0.2 -0.2 0.2 -0.2 -0.1 0.2 -0.1 1.4 0.2 1.0 0.6 -0.9 0.5 0.7 0.7 0.1 1.3 0.6 0.7 1.0
Other serious medical condition/disability diagnosed by doctor 0.5 0.6 3.1 0.1 -1.1 -0.3 -1.7 -0.2 -0.3 -0.7 -0.4 -0.9 -0.5 -0.5 -0.7 -1.1 -0.2 -1.1 0.8 0.8 -0.7 -0.6 -0.6 -1.1 -0.8 -0.7 -0.4 -0.6 -0.8 -0.4 -0.6 -1.1 -0.9 -0.6 0.3 -1.3 -0.4 -1.2 -0.6 -1.0 -0.5 0.1 -0.5 -1.1 -0.2
Ever used hormone-replacement therapy (HRT) 0.6 0.8 2.5 -0.4 -1.5 -0.6 -0.4 -0.6 -1.2 -1.4 -0.2 -1.2 -0.8 -1.2 -0.5 -1.3 -1.0 -1.1 -0.2 1.4 -0.6 -0.3 -0.0 -0.7 -0.8 -0.8 -0.6 -1.1 -1.2 -0.7 -1.1 -1.3 -1.6 -1.0 0.9 -0.8 -0.3 -0.7 -0.6 -0.7 -1.0 -0.7 -0.9 -0.6 -0.6
Ever had hysterectomy (womb removed) 1.1 1.3 3.3 0.7 1.0 1.4 -1.3 1.1 0.7 1.2 0.5 1.1 1.3 0.7 1.1 1.0 0.7 -0.1 1.6 -1.4 0.8 1.8 1.0 0.9 1.1 1.4 1.6 1.6 1.2 1.6 1.1 0.8 0.2 -0.4 -1.4 1.0 1.1 -1.8 -0.4 -1.3 1.4 0.1 0.1 -1.6 0.5
Systolic blood pressure, automated reading 6.5 18.8 45.3 5.2 4.7 4.5 1.6 5.6 6.7 4.7 2.6 4.9 5.0 1.8 3.6 4.7 5.8 3.5 2.1 -4.9 4.0 5.2 2.5 5.3 4.0 4.1 4.1 5.6 4.7 4.3 4.5 5.2 4.2 3.6 0.7 5.8 4.5 2.4 4.1 3.1 4.6 3.8 4.8 2.5 4.7
Eye problems/disorders: Diabetes related eye disease 5.5 6.0 11.3 3.1 2.2 2.7 2.3 3.2 2.8 2.1 2.7 2.7 2.3 2.4 2.2 2.1 1.4 2.6 1.6 -2.0 2.3 1.9 1.9 1.9 2.3 2.2 2.3 2.1 2.2 2.3 2.4 1.9 3.1 2.8 2.5 1.4 2.0 2.5 3.2 3.0 2.3 3.0 3.1 2.9 3.4
Angina 0.7 0.9 3.2 1.0 1.4 1.1 0.1 0.8 0.8 1.2 0.0 0.7 0.2 -0.2 0.8 1.4 0.4 0.4 1.0 -1.2 0.6 1.6 0.7 0.6 1.0 1.1 1.2 1.3 1.2 1.3 1.2 0.8 0.6 0.2 -0.6 1.8 1.2 -1.5 -0.3 -1.1 1.4 0.1 0.2 -0.8 0.6
Medication for hormone replacement therapy 0.5 0.6 2.4 -0.6 -0.7 -0.2 -1.1 -0.5 -0.7 -0.5 -0.4 -0.6 0.0 -1.4 -0.3 -0.5 -1.0 -1.0 0.1 0.6 -0.5 0.1 0.4 -1.2 -0.4 -0.2 -0.0 -0.4 -0.6 -0.0 -0.5 -0.7 -0.7 -1.0 -0.8 -1.1 -0.3 -1.5 -1.1 -1.4 -0.3 -0.8 -1.0 -1.2 -0.6
Vitamin and mineral supplements 0.3 0.4 2.8 1.3 0.5 0.7 0.1 0.6 0.3 0.6 -0.1 1.7 1.0 0.9 0.1 0.5 0.3 0.1 0.6 -0.6 -0.1 0.1 -0.3 0.4 0.5 0.2 0.3 0.2 0.5 0.4 0.4 0.3 1.2 0.5 0.7 0.5 -0.1 0.3 0.7 0.5 0.5 1.0 0.8 0.6 1.0
Supplements: Zinc 0.9 1.0 2.9 0.6 1.7 0.9 -1.0 0.8 0.6 1.6 -0.5 0.4 0.8 -0.3 0.8 1.5 0.6 0.5 0.0 -1.7 0.5 0.9 0.1 0.7 1.1 1.1 1.2 1.7 1.4 1.2 1.2 0.8 1.5 -0.4 -1.4 1.0 0.1 -1.2 -0.3 -0.9 1.5 1.5 0.4 -0.9 0.4
Medication: Co-codamol 2.6 3.0 5.2 -1.6 -2.0 -2.0 -0.9 -1.6 -1.7 -2.2 -1.9 -1.8 -1.1 -1.2 -2.1 -2.0 -1.4 -1.9 -2.1 2.0 -2.0 -1.9 -1.7 -1.7 -2.1 -1.9 -2.2 -2.0 -1.9 -2.2 -2.1 -2.0 -0.8 -1.7 -0.7 -2.0 -2.3 -0.6 -1.4 -0.9 -2.2 -0.9 -1.4 -1.1 -1.5
Medication: Metformin 0.5 0.7 3.7 -0.1 -1.1 -0.3 -0.9 -0.4 -1.3 -1.1 -0.2 -1.1 -0.8 -1.9 -0.3 -1.0 -1.0 -0.9 -0.3 1.2 -0.8 -1.4 -0.5 -0.2 -0.7 -0.7 -0.5 -1.2 -1.2 -0.6 -0.9 -1.1 -0.7 -0.3 0.8 -1.5 -0.5 -0.4 -0.2 -0.3 -0.9 -0.0 -0.4 -0.6 -0.2
Diabetes (father) 1.2 1.5 3.6 -1.6 -1.3 -1.0 -1.2 -1.4 -1.8 -1.3 -0.8 -1.8 -1.1 -1.9 -0.7 -1.2 -1.6 -1.1 -0.3 1.6 -0.6 -1.6 -1.0 -1.1 -1.1 -1.0 -0.8 -1.5 -1.5 -1.0 -1.3 -1.9 -1.2 -1.2 -0.2 -1.5 -1.1 -0.4 -0.9 -0.6 -1.1 -0.8 -1.3 -0.5 -1.1
Diabetes (mother) 0.3 0.4 3.9 1.1 -0.2 0.3 -0.2 0.8 0.6 -0.2 0.1 -0.7 0.4 -0.8 -0.4 -0.1 1.1 -0.0 0.1 0.3 -0.1 -0.1 -0.2 -0.3 -0.2 -0.2 0.0 -0.1 -0.2 0.0 0.0 -0.3 0.9 0.6 2.0 -0.3 -0.4 0.5 0.8 0.7 0.0 1.1 0.8 1.0 1.0
Severe depression (siblings) 4.5 5.1 8.8 1.6 2.2 2.3 2.5 1.7 1.5 2.1 3.0 2.8 1.5 2.4 2.5 2.3 1.7 2.7 2.4 -2.3 2.8 2.5 2.8 2.0 2.6 2.4 2.5 1.9 2.3 2.5 2.4 2.3 1.5 2.6 0.9 1.6 2.7 2.3 2.3 2.4 2.3 0.7 2.2 2.4 1.9
Pack years adult smoking proportion 1.5 2.3 8.9 -1.3 -1.0 -0.9 -2.4 -1.4 -1.4 -1.1 -1.4 -0.9 -1.3 -0.5 -0.5 -1.0 -1.5 -1.9 -1.4 1.1 -1.3 -1.0 -0.7 -1.1 -0.9 -0.7 -0.7 -1.3 -1.2 -0.7 -1.2 -2.0 -1.2 -2.1 -2.3 -1.8 -1.0 -3.0 -2.2 -2.7 -1.0 -1.3 -1.9 -2.7 -1.4
Impedance of leg (right) 0.3 1.4 5.2 -1.2 -1.0 -0.9 -2.3 -1.2 -1.4 -0.8 -1.3 0.4 -0.6 0.1 -0.6 -1.2 -0.8 -1.5 -0.0 0.8 -1.2 -0.9 -0.7 -0.6 -0.9 -0.6 -0.6 -0.8 -0.9 -0.7 -1.1 -0.9 -1.5 -1.8 -1.5 -0.9 -0.8 -1.9 -1.7 -1.9 -0.8 -1.3 -1.4 -1.9 -1.6
Leg fat-free mass (left) 0.2 1.2 3.3 -0.9 -0.7 -1.3 1.5 -1.0 -0.3 -1.0 -0.3 -1.7 -0.8 -1.6 -1.1 -0.6 -1.8 0.4 -1.5 1.2 -0.5 -1.2 -1.1 -1.1 -0.9 -1.3 -1.5 -1.3 -0.9 -1.5 -0.9 -0.4 0.5 0.4 0.8 -1.2 -1.3 1.8 0.3 1.2 -1.3 0.1 -0.1 1.4 -0.6
Trunk fat percentage 0.3 1.2 4.4 -0.8 -1.2 -0.8 0.9 -1.0 -1.0 -1.5 0.7 -1.2 -0.9 -1.4 -0.0 -1.1 -2.1 -0.0 -0.9 1.6 0.0 -1.4 0.4 -0.2 -0.6 -0.8 -0.9 -1.8 -1.3 -1.0 -1.1 -1.6 -0.8 0.4 1.9 -2.1 -0.2 1.2 0.4 0.9 -1.3 -0.2 -0.1 1.0 -0.3
Hand grip strength (right) 0.3 0.9 5.6 1.0 1.1 0.2 -0.7 1.0 1.6 0.8 -1.4 0.3 0.3 -0.0 -1.0 1.0 2.4 0.4 -0.6 -0.9 -0.5 0.5 -1.6 -0.2 -0.2 0.1 -0.1 1.0 0.9 0.1 0.6 0.9 2.0 0.2 -0.8 1.7 -0.8 0.4 0.4 0.4 0.6 1.4 0.9 0.3 0.9
Townsend deprivation index at recruitment 0.9 1.3 3.0 0.8 1.2 1.3 0.5 0.9 0.6 1.1 1.4 0.9 1.5 0.3 1.4 1.0 -0.3 1.2 1.5 -1.1 1.2 1.4 1.6 1.3 1.3 1.3 1.4 1.0 1.3 1.4 1.3 1.3 0.6 1.4 -0.0 1.0 1.7 0.9 1.1 1.0 1.3 1.2 1.3 0.8 1.0
Current tobacco smoking 0.3 0.5 2.0 -0.5 0.3 0.5 -0.3 -0.4 -0.3 0.5 0.7 -0.8 0.4 -0.2 1.2 0.4 -0.9 0.0 1.4 -0.3 0.5 0.7 1.1 0.8 0.8 0.9 0.9 0.2 0.4 0.8 0.4 0.8 -0.9 -0.5 -1.0 -0.4 0.8 -1.2 -0.7 -1.1 0.5 -0.3 -0.6 -1.0 -0.6
Average weekly fortified wine intake 0.3 0.3 2.9 0.5 -0.4 -0.4 -0.4 0.2 0.0 -0.4 -0.9 -1.7 0.2 0.3 -0.8 -0.5 0.6 -0.6 -0.2 0.0 -0.9 -1.0 -1.0 -0.2 -0.6 -0.4 -0.7 -0.4 -0.1 -0.5 -0.5 -0.2 0.4 -0.1 1.2 0.1 -0.5 0.1 0.2 0.1 -0.4 0.6 0.3 0.1 0.3
Maternal smoking around birth 0.7 1.1 2.5 1.2 1.0 1.1 1.3 1.1 1.0 1.0 1.0 -0.5 1.4 0.5 0.8 1.0 0.5 1.1 0.8 -0.9 0.9 0.3 1.0 1.3 1.2 1.0 1.0 0.8 1.0 1.0 1.0 0.7 1.6 1.0 0.5 0.3 0.6 1.5 1.4 1.5 1.0 1.0 1.2 1.2 1.4
Fed-up feelings 0.1 0.1 1.2 0.0 0.4 0.0 0.5 -0.0 -0.0 0.5 -0.0 -0.6 1.1 -0.5 0.1 0.2 -0.0 0.3 1.1 -0.3 0.2 0.0 0.2 0.2 0.3 -0.0 0.1 0.4 0.3 0.1 0.3 0.7 0.5 0.2 -0.1 0.2 0.0 0.3 0.1 0.2 0.3 -0.2 0.2 0.5 -0.1
Frequency of unenthusiasm / disinterest in last 2 weeks 0.1 0.2 2.1 -0.6 -0.3 -0.2 0.3 -0.5 -1.0 -0.1 0.4 -0.5 -0.4 -0.5 0.0 -0.2 -1.5 0.1 0.8 0.3 0.1 -0.3 0.3 -0.5 -0.1 -0.1 -0.0 -0.5 -0.1 -0.1 -0.1 0.1 -0.6 -0.2 0.2 -0.8 -0.1 -0.0 -0.2 -0.1 -0.2 -0.1 -0.2 -0.1 -0.4
Relative age voice broke 0.1 0.2 1.8 0.1 -0.0 0.2 -1.4 0.2 -0.4 0.2 -0.3 1.1 0.4 -0.3 0.2 -0.2 0.2 -0.6 0.5 -0.0 -0.3 -0.1 0.1 -0.2 0.0 0.2 0.3 0.1 -0.0 0.3 -0.0 0.1 0.1 -0.4 0.0 -0.6 -0.6 -0.7 -0.3 -0.6 0.2 0.5 -0.1 -1.1 0.1
Taking other prescription medications 0.4 0.6 2.4 -0.8 -1.0 -0.6 0.1 -1.0 -0.9 -0.9 0.3 -1.5 -0.7 -0.6 0.1 -0.9 -0.6 -0.5 0.4 0.9 -0.0 -0.6 0.3 -0.2 -0.4 -0.5 -0.4 -0.8 -0.8 -0.5 -0.7 -1.2 -1.2 -0.5 -0.2 -1.5 -0.1 -0.6 -0.7 -0.7 -0.7 -0.3 -1.0 -0.8 -1.0
Age when periods started (menarche) 0.1 0.2 2.3 0.5 -0.3 -0.0 -0.2 0.6 0.6 -0.3 -0.3 0.6 -0.6 0.4 -0.5 -0.2 1.5 -0.3 -0.5 0.3 -0.3 -0.5 -1.0 -0.2 -0.6 -0.5 -0.4 -0.1 -0.3 -0.4 -0.3 -0.4 0.4 -0.3 1.0 0.1 -0.9 -0.1 0.2 0.0 -0.3 0.5 0.2 -0.0 0.5
Bilateral oophorectomy (both ovaries removed) 0.7 0.8 2.7 -0.1 1.1 0.9 -0.7 0.3 0.1 1.1 -0.1 0.0 0.6 -0.1 0.6 1.2 0.3 -0.1 1.4 -1.1 0.7 1.6 1.1 0.6 1.0 1.0 1.2 1.3 1.0 1.3 1.0 0.8 0.3 -0.4 -1.5 1.1 0.5 -1.2 -0.5 -1.0 1.2 0.1 -0.2 -1.0 -0.1
Heel bone mineral density (BMD) T-score, automated (left) 0.2 0.3 1.8 0.7 -0.4 -0.4 0.4 0.2 0.1 -0.2 -0.7 -0.5 0.4 -0.2 -0.8 -0.3 -0.6 -0.6 -1.3 0.0 -1.1 -1.0 -1.0 -0.9 -0.6 -0.5 -0.5 -0.0 -0.3 -0.6 -0.3 0.1 0.7 -0.4 0.6 -0.5 -0.8 -0.7 -0.3 -0.5 -0.3 0.6 0.2 -0.5 0.1
Tinnitus: Yes, but not now, but have in the past 0.2 0.2 1.5 0.5 0.3 -0.0 0.1 0.2 0.2 0.3 -1.2 -0.8 0.1 -0.2 -0.7 0.3 0.4 -0.3 -0.2 -0.2 -0.6 0.3 -0.8 -0.0 -0.0 -0.2 -0.1 0.6 0.1 -0.1 0.2 0.5 0.3 -0.1 -0.9 0.9 -0.5 -0.2 -0.2 -0.2 0.2 -0.4 -0.0 -0.3 -0.1
Qualifications: CSEs or equivalent 0.2 0.2 1.4 -0.7 -0.3 -0.5 -0.5 -0.1 -0.2 -0.5 -0.5 0.3 -0.7 0.2 -0.6 -0.4 0.4 -0.1 -0.4 0.6 -0.1 -0.1 -0.7 -0.7 -0.6 -0.5 -0.4 -0.3 -0.5 -0.5 -0.4 -0.8 0.5 -0.4 -0.6 -1.2 -0.8 0.2 -0.2 0.1 -0.5 0.1 -0.1 0.3 -0.3
Serious illness, injury or assault to yourself 1.7 2.1 6.1 1.7 1.2 2.1 -0.4 1.8 1.8 1.4 1.4 2.5 0.9 0.6 1.7 1.2 1.1 0.5 2.3 -1.4 1.5 2.2 1.9 1.5 1.6 1.7 2.1 1.4 1.3 2.0 1.5 0.6 1.0 0.9 0.1 0.2 1.7 0.1 1.2 0.6 1.7 0.9 1.3 0.1 1.8
High blood pressure 4.5 12.7 31.8 4.0 3.7 3.3 2.8 4.4 5.6 3.6 2.3 3.5 3.6 1.9 2.8 3.5 5.1 3.1 1.7 -3.6 3.6 4.7 2.3 4.6 3.1 3.2 3.2 4.6 3.7 3.3 3.6 4.0 3.3 3.4 1.3 4.7 3.8 2.9 3.6 3.2 3.6 2.9 3.8 2.6 3.6
Hayfever, allergic rhinitis or eczema 0.3 0.5 2.5 -0.5 0.7 0.2 1.6 -0.5 -0.8 0.5 0.7 -0.2 0.2 1.5 1.0 0.5 -0.6 1.0 1.0 -0.1 0.9 0.1 0.8 0.9 0.9 0.4 0.4 0.3 0.3 0.3 0.4 0.4 -0.2 1.0 -1.1 0.2 0.6 1.5 0.6 1.1 0.3 -0.2 0.3 1.0 -0.5
Multivitamins +/- minerals 0.3 0.4 4.0 -1.1 -0.4 -0.9 -0.1 -0.8 -0.4 -0.4 -0.5 -2.0 -0.0 -0.3 -0.6 -0.4 -0.5 -0.2 -0.7 0.4 -0.6 -0.8 -0.3 -0.6 -0.6 -0.5 -0.6 -0.2 -0.4 -0.6 -0.5 -0.0 -0.6 -0.3 -0.9 -0.3 -0.3 -0.1 -0.7 -0.4 -0.5 -1.1 -0.8 -0.6 -1.0
Stomach or abdominal pain in last month 0.3 0.4 1.2 -0.6 -0.6 -0.9 0.7 -0.7 -0.5 -0.5 -0.6 -0.0 -0.2 -0.4 -1.1 -0.5 -1.1 -0.3 -0.8 0.8 -0.6 -0.8 -0.9 -0.8 -0.7 -1.0 -0.9 -0.6 -0.7 -0.9 -0.6 -0.4 -0.1 0.1 -0.4 -0.1 -0.8 0.6 -0.2 0.3 -0.7 -0.3 -0.3 0.4 -0.5
Supplements: Glucosamine 0.1 0.2 0.8 0.1 0.6 0.0 0.6 -0.0 -0.5 0.5 0.4 -0.8 -0.3 0.6 0.2 0.7 -0.4 0.7 0.1 -0.6 0.1 0.2 -0.0 -0.2 0.4 0.2 0.1 0.5 0.7 0.2 0.4 0.6 0.6 0.1 0.2 0.8 -0.1 0.3 0.1 0.2 0.4 0.9 0.3 0.6 -0.1
Diverticular disease/diverticulitis (self-reported) 1.8 2.1 5.2 -1.3 -1.6 -1.0 -2.1 -1.3 -2.2 -1.8 -0.8 -1.0 -1.7 -0.2 -0.5 -1.7 -1.7 -1.9 -0.6 1.5 -1.1 -1.4 -0.6 -1.8 -1.4 -1.0 -0.9 -1.5 -1.5 -0.9 -1.5 -2.3 -1.8 -1.9 -0.6 -1.8 -0.8 -1.6 -1.5 -1.6 -1.4 -1.1 -1.6 -1.7 -1.3
Medication: Atenolol 4.0 5.0 11.5 1.6 2.7 2.4 1.3 2.7 3.0 2.6 1.3 2.2 1.5 1.8 1.7 2.7 2.9 1.9 1.3 -2.8 2.1 3.4 1.9 2.5 2.5 2.6 2.5 3.1 2.8 2.6 2.6 1.7 2.3 1.3 -1.2 3.3 2.3 0.4 1.4 0.8 2.8 1.1 1.9 0.9 2.3
Medication: Levothyroxine sodium 0.2 0.3 1.8 0.7 0.1 0.4 -1.4 0.7 0.4 0.0 -0.3 0.6 0.7 0.2 0.1 -0.1 0.9 -0.5 0.4 -0.3 -0.4 0.4 -0.3 0.2 -0.1 0.3 0.2 0.1 0.3 0.2 0.1 -0.5 0.3 -0.6 0.3 0.8 -0.0 -0.5 0.2 -0.2 0.2 1.1 0.5 -0.7 0.8
Sitting height 0.2 1.1 3.8 -1.9 -0.6 -1.6 0.6 -1.9 -0.8 -0.5 -0.8 -1.0 -0.9 -0.9 -1.1 -0.3 -1.9 -0.1 -1.0 0.7 -0.5 -1.1 -1.0 -1.0 -0.8 -1.1 -1.3 -1.0 -0.8 -1.3 -0.8 0.1 -0.8 -0.6 -1.6 -0.5 -1.0 0.6 -1.0 -0.1 -1.1 -1.4 -1.0 0.2 -1.9
Chronic bronchitis/emphysema (father) 0.4 0.4 2.8 -0.4 0.8 0.4 0.5 0.2 0.3 0.9 0.3 -0.8 -0.9 0.2 0.3 1.1 -0.8 0.5 -0.1 -0.5 0.4 1.3 0.4 0.3 0.9 0.5 0.7 1.1 0.6 0.7 0.9 1.0 0.2 0.5 -1.7 0.9 0.2 0.1 0.0 0.0 0.9 -0.5 -0.2 0.1 -0.2
High blood pressure (mother) 0.5 0.8 4.1 -0.5 0.5 0.4 -0.8 0.2 0.5 0.5 0.1 -0.9 0.7 -1.2 0.7 0.5 1.7 -0.2 1.1 -0.7 0.9 1.5 0.4 0.6 0.5 0.8 0.9 1.2 0.7 0.8 0.5 0.8 -0.5 -0.7 -2.0 0.5 0.8 -1.4 -0.9 -1.3 0.7 -0.5 -0.4 -1.4 -0.7
Body mass index (BMI) 0.3 1.3 4.8 -0.7 -1.1 -1.0 1.5 -0.8 -0.8 -1.4 0.3 -1.6 -1.3 -2.2 -0.8 -0.8 -1.9 0.2 -1.2 1.4 -0.4 -1.2 -0.3 -0.9 -0.7 -1.2 -1.3 -1.5 -1.1 -1.2 -1.0 -1.0 -0.0 0.7 1.8 -1.6 -0.7 1.8 0.6 1.4 -1.2 0.1 0.0 1.6 -0.2
Impedance of leg (left) 0.1 0.6 3.4 -0.6 -0.3 -0.5 -1.8 -0.7 -0.8 -0.2 -1.1 0.7 -0.0 1.0 -0.3 -0.6 -0.3 -1.0 0.1 0.2 -0.8 -0.4 -0.5 -0.1 -0.4 -0.2 -0.2 -0.2 -0.4 -0.2 -0.5 -0.3 -0.9 -1.1 -1.1 0.0 -0.4 -1.4 -1.1 -1.4 -0.2 -0.5 -0.8 -1.3 -0.9
Leg predicted mass (left) 0.2 1.2 3.4 -0.8 -0.7 -1.3 1.5 -1.0 -0.2 -1.0 -0.3 -1.7 -0.8 -1.6 -1.1 -0.6 -1.7 0.4 -1.5 1.2 -0.5 -1.3 -1.1 -1.0 -1.0 -1.4 -1.6 -1.4 -0.9 -1.5 -0.9 -0.4 0.5 0.4 0.9 -1.3 -1.3 1.9 0.3 1.3 -1.3 0.1 -0.1 1.5 -0.5
Trunk fat mass 0.4 1.6 5.6 -1.0 -1.3 -1.3 1.0 -1.2 -1.1 -1.6 0.1 -1.7 -1.2 -1.8 -0.6 -1.2 -2.4 -0.1 -1.4 1.7 -0.4 -1.7 -0.4 -0.7 -0.9 -1.3 -1.4 -2.0 -1.4 -1.5 -1.4 -1.5 -0.5 0.4 1.9 -2.0 -0.9 1.5 0.3 1.1 -1.6 0.0 -0.2 1.2 -0.6
Waist circumference 0.5 1.9 8.0 -1.4 -1.4 -1.5 0.9 -1.6 -1.6 -1.6 -0.0 -1.8 -1.5 -1.9 -0.9 -1.2 -2.8 -0.1 -1.5 1.8 -0.7 -1.7 -0.5 -1.1 -1.0 -1.5 -1.6 -2.0 -1.5 -1.6 -1.4 -1.2 -0.7 0.3 1.1 -2.1 -1.1 1.4 -0.0 0.9 -1.6 -0.6 -0.7 1.1 -1.0
Number of incorrect matches in round 1.4 2.3 5.3 -1.8 -1.9 -1.6 -1.2 -1.6 -1.7 -1.6 -1.0 -0.5 -2.3 -0.8 -1.6 -1.6 -1.4 -1.6 -1.4 1.5 -1.4 -0.9 -0.9 -1.5 -1.6 -1.3 -1.4 -1.5 -1.5 -1.4 -1.5 -2.0 -2.2 -1.6 -0.8 -1.1 -0.8 -1.5 -1.8 -1.6 -1.5 -2.3 -1.8 -1.8 -1.5
Past tobacco smoking 0.1 0.3 2.8 0.7 -0.0 0.6 -0.2 1.1 0.2 0.0 0.2 0.5 -0.5 -0.8 -0.0 0.1 1.0 0.0 -0.6 0.3 0.1 -0.3 -0.0 -0.0 -0.3 -0.1 0.3 0.4 -0.3 0.2 0.2 -0.3 0.3 0.2 1.7 -0.5 -0.2 -0.6 0.3 -0.2 0.2 0.4 0.4 -0.1 0.9
Alcohol usually taken with meals 0.8 1.2 5.4 1.6 1.3 1.3 -0.2 1.6 1.5 1.4 0.1 0.4 1.0 0.7 0.4 1.7 1.4 0.6 0.6 -1.5 0.8 1.4 0.4 1.2 1.1 1.0 1.3 1.7 1.2 1.3 1.4 0.4 0.8 0.3 0.4 2.3 0.6 -0.3 0.7 0.1 1.5 0.9 0.8 0.1 1.3
Nervous feelings 0.6 1.1 3.6 1.5 0.9 0.4 1.7 0.7 0.5 1.0 0.0 -0.2 1.0 -0.1 -0.3 1.0 1.3 1.1 0.6 -1.2 0.2 -0.3 -0.6 1.0 0.6 0.2 0.1 0.8 1.0 0.2 0.8 1.1 1.9 1.4 1.0 1.4 0.1 1.7 1.3 1.6 0.7 1.8 1.4 1.6 0.9
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.6 2.6 -1.1 -0.5 -0.7 0.3 -1.3 -1.1 -0.3 -0.1 -0.9 -0.6 -1.6 -0.3 -0.2 -1.4 -0.3 0.6 0.3 -0.1 -0.4 0.2 -1.0 -0.2 -0.3 -0.4 -0.8 -0.2 -0.4 -0.4 -0.2 -0.2 -0.6 -1.6 -1.6 -0.6 -0.5 -0.9 -0.7 -0.5 -1.2 -0.8 -0.6 -1.2
Hearing difficulty/problems with background noise 0.4 0.6 3.3 0.4 -0.5 -0.8 1.1 -0.0 0.4 -0.5 0.1 -0.3 0.1 0.1 -0.7 -0.5 -0.7 0.2 -0.7 0.3 -0.6 -0.6 -0.9 0.4 -0.4 -0.6 -1.0 -0.6 -0.1 -1.0 -0.6 0.0 0.1 0.7 1.6 1.0 0.1 1.8 0.9 1.5 -0.7 0.6 0.9 1.6 0.2
Hair/balding pattern: Pattern 2 0.8 1.0 2.6 1.1 0.7 1.0 1.0 1.1 0.8 0.9 0.9 1.0 1.3 1.4 0.6 0.8 1.3 0.9 1.4 -0.9 0.8 1.1 0.7 1.3 0.7 0.9 1.0 0.9 0.9 1.0 1.0 1.1 0.3 1.1 0.4 1.5 1.6 0.4 0.8 0.6 0.9 -0.0 1.1 0.9 1.0
Had menopause 1.0 1.2 3.2 -0.7 -1.0 -1.4 -1.2 -0.9 -1.4 -0.9 -1.6 -1.2 -0.9 0.0 -1.6 -1.1 -0.7 -1.3 -1.6 0.9 -1.8 -1.2 -1.6 -0.8 -1.2 -1.5 -1.5 -0.9 -1.0 -1.4 -1.2 -1.1 -0.9 -0.7 0.6 0.3 -1.4 -0.3 -0.8 -0.5 -1.1 -0.5 -0.8 -0.7 -0.9
Had other major operations 0.4 0.5 2.1 0.3 0.8 0.9 -0.3 0.7 0.6 0.9 0.5 0.3 -0.2 0.2 0.8 0.6 -0.2 0.5 1.4 -0.7 0.6 1.4 0.8 0.6 0.8 0.8 1.0 1.0 0.7 1.0 0.9 0.9 -0.5 0.1 -0.3 1.2 1.1 -0.1 0.3 0.0 1.0 0.2 0.3 -0.4 0.5
Forced vital capacity (FVC) 0.1 0.5 2.3 0.8 0.6 0.1 0.8 0.5 1.1 0.7 -0.3 0.7 0.7 -0.0 -0.3 0.5 0.5 0.7 -0.3 -0.6 -0.1 0.4 -0.5 0.1 0.0 0.1 -0.1 0.4 0.6 -0.0 0.4 0.8 1.3 0.9 0.9 0.5 -0.1 1.2 0.8 1.1 0.3 1.5 1.0 0.9 0.6
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.4 2.2 0.9 -0.1 -0.4 0.0 0.3 -0.0 0.2 -1.2 -0.3 0.9 0.2 -1.0 -0.1 -1.0 -0.7 -1.5 -0.5 -1.4 -1.0 -1.3 -0.7 -0.4 -0.5 -0.5 0.3 0.1 -0.5 -0.2 0.4 0.7 -0.3 0.8 0.3 -0.8 -0.6 -0.3 -0.4 -0.1 0.7 0.4 -0.7 0.2
Ever unenthusiastic/disinterested for a whole week 0.3 0.3 1.8 -0.2 0.5 0.4 0.4 0.1 0.5 0.6 0.5 0.2 0.6 -0.8 0.4 0.5 0.1 0.4 1.4 -0.9 0.6 0.8 0.7 0.1 0.5 0.6 0.6 0.7 0.7 0.6 0.7 0.7 0.3 0.0 -1.0 -0.2 0.6 -0.8 -0.4 -0.7 0.6 -0.4 0.1 -0.2 -0.3
Qualifications: None of the above 0.3 0.6 4.2 0.6 -0.6 0.1 -1.4 0.2 0.6 -0.4 -0.7 -1.6 -0.0 -1.3 -0.5 -0.6 0.7 -1.1 -0.1 0.2 -0.6 0.1 -0.3 -0.6 -0.6 -0.3 0.0 -0.1 -0.4 0.1 -0.3 -0.7 -0.2 -0.9 -0.1 -0.7 -0.5 -2.0 -0.9 -1.6 -0.1 0.6 -0.6 -1.8 0.1
Financial difficulties in last 2 years 0.3 0.4 1.6 0.6 0.1 0.5 0.8 0.5 -0.0 0.2 1.2 1.2 1.2 0.5 0.8 0.0 -1.1 0.6 0.8 -0.0 0.5 -0.0 1.3 0.8 0.6 0.5 0.6 0.1 0.3 0.5 0.4 0.3 0.4 0.5 0.3 -0.6 0.9 0.7 0.8 0.8 0.3 0.3 0.7 0.7 0.6
Mouth/teeth dental problems 0.3 0.5 5.1 -1.8 0.1 -0.8 -0.6 -1.0 -0.7 0.2 -0.7 -0.1 -0.3 0.0 -0.5 0.1 -1.1 -0.1 -0.8 -0.1 -0.7 -0.4 -0.4 -0.4 0.0 -0.2 -0.5 0.0 0.0 -0.4 -0.2 0.4 0.0 -0.4 -2.3 0.2 -0.6 -0.4 -1.1 -0.7 -0.2 -1.3 -0.8 -0.6 -1.3
Heart attack 3.7 4.7 10.9 2.5 2.4 2.4 0.9 2.4 2.9 2.4 1.9 3.1 2.0 2.2 2.1 2.3 2.2 1.9 1.8 -2.4 2.0 3.3 1.8 2.4 2.3 2.2 2.4 2.7 2.4 2.5 2.4 2.0 1.4 1.7 0.7 3.2 2.7 0.5 1.6 0.9 2.5 1.6 1.7 1.0 2.1
Allergy 0.2 0.5 4.9 1.2 -0.6 -0.0 -0.2 0.9 1.0 -0.5 -0.3 0.6 0.2 -0.7 -0.9 -0.4 1.3 -0.4 -0.8 -0.1 -0.7 -0.1 -0.8 -0.4 -0.8 -0.3 -0.5 -0.3 -0.1 -0.5 -0.3 -0.1 0.9 0.1 2.2 0.2 -0.1 0.1 0.6 0.4 -0.3 0.3 0.7 0.4 1.2
Pain all over the body in last month 2.8 3.0 5.7 1.9 2.0 1.9 1.1 1.7 1.5 2.0 1.6 2.4 1.4 1.7 1.6 2.2 0.4 1.8 1.6 -1.8 1.8 2.2 1.2 1.6 2.1 1.6 1.8 1.9 1.9 1.8 1.9 1.6 1.8 1.7 0.4 1.6 1.3 1.6 1.8 1.7 1.9 1.8 2.1 1.7 1.6
Diabetes (self-reported) 1.1 1.8 4.1 1.9 1.2 2.0 -0.2 1.9 1.1 1.2 1.1 0.8 1.5 -0.1 1.3 1.2 1.1 0.9 1.3 -1.3 1.1 1.1 1.3 0.9 1.3 1.6 1.8 1.4 1.3 1.7 1.5 0.8 1.6 1.2 1.1 0.4 1.3 0.4 1.5 0.9 1.6 1.9 1.7 0.4 2.0
Hayfever/allergic rhinitis (self-reported) 2.4 3.1 7.3 0.5 2.7 1.7 1.7 1.4 1.1 2.4 1.1 0.6 1.5 1.7 1.8 2.4 1.4 2.1 0.9 -2.2 1.9 2.1 1.6 2.2 2.4 2.1 2.0 2.5 2.3 2.1 2.2 1.9 1.6 1.2 -1.5 2.3 1.4 1.0 0.9 1.0 2.3 0.9 1.4 1.3 0.9
Medication: Ramipril 4.8 6.2 11.8 2.4 2.9 2.7 2.2 2.6 3.0 2.7 2.0 2.7 1.9 1.5 2.7 2.8 3.4 2.4 2.5 -2.6 3.0 3.0 2.5 3.3 2.7 2.6 2.8 2.8 2.6 2.8 2.7 2.2 2.2 2.2 0.6 2.2 2.6 1.4 2.2 1.8 2.7 2.1 2.0 1.5 2.5
Medication: Simvastatin 1.3 1.9 3.8 1.6 1.5 1.7 0.5 1.5 1.8 1.4 1.4 1.4 1.2 -0.2 1.9 1.4 1.9 1.2 1.2 -1.5 1.8 1.7 1.6 1.7 1.4 1.7 1.7 1.5 1.6 1.6 1.4 1.4 1.1 1.1 0.4 0.8 1.9 0.1 1.0 0.4 1.5 1.3 1.3 0.2 1.3
Fluid intelligence score 1.3 2.7 13.2 1.7 1.7 1.6 0.0 1.8 1.8 1.8 0.7 2.8 2.9 3.6 1.1 1.7 1.2 1.1 0.7 -2.2 1.2 1.4 0.7 1.7 1.4 1.5 1.3 1.7 1.8 1.4 1.5 1.4 1.8 1.2 0.2 2.7 1.7 0.3 1.1 0.7 1.5 1.7 1.8 0.9 1.6
Illnesses of siblings 0.2 0.3 2.2 0.1 0.3 0.6 0.7 0.5 -0.1 0.4 0.6 1.5 0.4 1.0 0.4 0.2 0.5 0.4 1.0 -0.4 0.4 -0.2 0.5 -0.0 0.4 0.5 0.4 0.1 0.3 0.3 0.4 -0.6 1.0 0.2 -0.1 -0.4 -0.1 0.2 0.5 0.4 0.3 0.9 0.6 0.7 0.8
Neuroticism score 0.2 0.5 2.5 0.9 0.5 -0.0 1.4 0.3 0.3 0.7 -0.0 -0.3 1.1 -1.1 -0.3 0.5 0.5 0.8 0.3 -0.7 0.1 -0.1 -0.5 0.4 0.2 -0.1 -0.2 0.4 0.7 -0.1 0.4 1.0 1.6 0.7 0.7 0.9 0.1 1.0 0.7 0.9 0.3 0.6 0.8 1.3 0.4
Weight 0.3 1.7 5.6 -1.1 -0.9 -1.6 1.7 -1.3 -0.8 -1.2 -0.3 -1.9 -1.3 -1.9 -1.2 -0.7 -2.4 0.4 -1.6 1.4 -0.7 -1.4 -1.1 -1.1 -0.9 -1.6 -1.7 -1.6 -1.1 -1.7 -1.1 -0.6 0.1 0.7 1.3 -1.2 -1.3 2.2 0.4 1.5 -1.5 0.2 -0.1 1.8 -0.7
Impedance of arm (right) 0.7 3.3 14.0 -2.8 -1.7 -0.9 -1.8 -2.3 -2.5 -1.4 0.1 0.0 -0.9 0.7 0.5 -1.9 -1.8 -1.8 0.4 1.7 -0.1 -0.8 1.0 -0.2 -0.7 -0.3 -0.2 -1.6 -1.7 -0.5 -1.5 -1.9 -3.7 -2.3 -2.4 -2.1 0.2 -2.6 -2.4 -2.6 -1.2 -3.3 -2.6 -2.6 -2.5
Arm fat percentage (right) 0.7 2.7 8.5 -1.7 -2.2 -1.6 1.1 -1.8 -1.9 -2.4 0.4 -1.8 -1.8 -2.2 -0.7 -2.0 -2.6 -0.6 -1.3 2.5 -0.6 -2.0 0.1 -1.2 -1.3 -1.6 -1.6 -2.7 -2.1 -1.7 -1.9 -2.3 -1.5 -0.1 1.6 -2.9 -0.8 1.1 -0.2 0.6 -2.1 -1.1 -0.9 0.8 -1.1
Trunk fat-free mass 0.3 2.0 6.5 -0.7 -0.6 -2.0 1.3 -1.2 -0.2 -0.7 -1.5 -1.6 -1.2 -1.6 -2.2 -0.5 -1.8 0.3 -1.9 0.9 -1.5 -1.4 -2.5 -1.8 -1.3 -2.0 -2.3 -1.1 -0.8 -2.1 -1.0 0.2 1.0 0.5 0.7 -0.2 -2.1 2.3 0.3 1.5 -1.4 0.6 -0.0 1.7 -0.8
Hip circumference 0.3 1.4 7.6 -1.0 -0.8 -1.2 2.3 -1.1 -0.7 -1.1 0.6 -1.3 -0.9 -1.6 -0.5 -0.6 -1.4 0.7 -1.2 1.2 0.1 -1.0 0.1 -0.3 -0.5 -1.0 -1.3 -1.4 -0.9 -1.3 -0.8 -0.5 -0.3 1.2 1.7 -1.1 -0.4 2.8 0.9 2.1 -1.2 -0.4 0.2 2.2 -0.5
Time employed in main current job 2.2 2.6 7.8 -2.1 -1.2 -1.0 -2.6 -1.6 -1.8 -1.2 -1.6 -1.6 -1.3 -1.4 -1.0 -0.9 -0.9 -2.3 -0.9 1.0 -1.3 -0.7 -0.4 -1.3 -1.1 -0.6 -0.6 -0.9 -1.1 -0.6 -1.1 -1.7 -1.8 -2.0 -2.6 -1.5 -1.1 -2.6 -2.3 -2.5 -0.9 -1.9 -2.0 -2.8 -1.8
Alcohol intake versus 10 years previously 0.9 1.3 6.5 0.6 0.5 0.4 2.5 0.6 0.8 0.4 1.8 1.1 0.9 0.7 1.3 0.5 -1.2 1.5 0.4 -0.1 1.2 -0.1 1.5 1.7 0.5 0.4 0.4 0.2 0.3 0.4 0.5 1.2 0.1 1.9 2.0 0.2 1.3 2.2 1.6 2.0 0.3 0.7 1.0 2.0 0.8
Father’s age at death 0.4 0.5 5.3 -1.0 -0.2 -0.5 1.2 -1.3 -1.5 -0.2 0.6 -0.3 -0.7 0.6 0.4 -0.2 -2.3 0.6 -0.1 0.5 0.1 -0.9 0.6 -0.5 -0.1 -0.2 -0.2 -0.9 -0.4 -0.3 -0.2 -0.1 -1.1 0.1 -0.4 -0.3 -0.1 1.2 0.1 0.8 -0.4 -0.4 -0.4 0.5 -0.8
Worrier / anxious feelings 0.2 0.5 3.6 0.0 0.7 -0.4 -0.0 -0.1 -0.2 0.6 -1.4 -0.8 -0.3 -1.9 -0.9 0.7 0.7 -0.1 -0.5 -0.7 -0.7 0.1 -1.4 -0.4 0.0 -0.4 -0.4 0.7 0.4 -0.2 0.2 0.7 0.9 -0.3 -1.1 1.3 -1.0 -0.2 -0.5 -0.3 0.3 -0.3 -0.2 -0.3 -0.5
Frequency of tiredness / lethargy in last 2 weeks 1.8 2.9 6.0 1.7 1.6 1.5 1.9 1.5 1.0 1.7 1.7 1.2 1.7 -0.2 1.4 1.7 0.6 2.2 2.4 -1.4 1.8 1.2 1.3 1.8 1.6 1.4 1.4 1.5 1.6 1.4 1.7 2.2 1.5 2.4 1.5 1.5 1.9 2.5 2.2 2.4 1.6 1.9 2.0 2.4 1.5
Falls in the last year 2.4 3.2 9.3 1.9 1.1 1.4 2.9 1.8 1.7 1.0 2.4 1.1 1.0 0.1 1.4 1.2 0.9 2.1 1.7 -1.1 1.7 1.4 1.5 1.9 1.3 1.3 1.1 1.3 1.4 1.2 1.5 1.6 1.3 2.2 2.7 1.3 1.9 3.0 2.6 3.0 1.2 2.0 2.3 2.9 1.9
Hair/balding pattern: Pattern 3 0.2 0.3 1.8 -0.0 -0.8 -0.3 -0.9 -0.2 0.1 -0.7 -0.2 0.3 -0.8 0.1 -0.3 -0.6 -0.4 -0.8 -0.8 0.5 -0.3 -0.2 -0.1 -0.0 -0.4 -0.1 -0.3 -0.5 -0.4 -0.3 -0.5 -1.3 -0.3 -1.1 0.8 -0.8 -0.5 -0.7 -0.4 -0.5 -0.4 0.4 -0.2 -0.9 -0.1
Number of live births 0.3 0.5 2.8 0.0 -0.7 0.0 -1.7 -0.2 -0.9 -0.6 -0.3 -1.0 -0.3 0.2 0.0 -0.8 -1.0 -0.9 0.3 0.9 -0.7 -0.7 -0.5 -0.1 -0.3 -0.4 -0.2 -0.8 -0.8 -0.3 -0.6 -0.9 -1.0 -0.8 0.8 -0.7 -0.4 -1.2 -0.4 -0.9 -0.4 0.5 -0.6 -1.1 0.1
Forced expiratory volume in 1-second (FEV1) 0.1 0.3 1.4 0.9 0.3 0.2 0.5 0.4 0.7 0.4 -0.3 0.1 0.8 0.0 -0.3 0.3 0.2 0.3 -0.3 -0.3 -0.3 0.0 -0.3 -0.1 -0.2 0.0 -0.1 0.1 0.3 -0.1 0.2 0.6 0.9 0.7 1.1 0.2 -0.1 1.0 0.7 0.9 0.2 1.2 0.9 0.6 0.6
Pulse rate 0.4 0.6 3.6 0.7 0.6 1.2 -0.4 0.8 0.7 0.7 0.4 -0.4 1.4 0.9 0.8 0.7 1.0 0.1 0.6 -0.9 0.7 0.3 1.0 1.9 0.8 1.0 1.2 0.7 0.7 1.2 0.8 0.5 0.5 0.4 0.1 0.4 0.7 -0.2 0.5 0.1 1.0 0.6 0.6 -0.1 1.0
Happiness 0.5 0.6 3.2 -0.2 0.8 0.1 1.8 -0.2 0.2 0.8 0.9 1.0 -0.1 0.3 0.4 0.8 0.6 1.3 1.3 -0.9 0.8 0.4 0.5 0.5 0.6 0.4 0.4 0.7 0.9 0.4 0.8 1.8 0.7 0.9 -0.3 0.4 0.4 1.1 0.2 0.8 0.6 -0.1 0.3 1.2 -0.3
Noisy workplace 0.9 1.2 3.3 1.2 0.7 1.3 1.3 1.0 1.2 0.9 1.6 1.8 0.9 0.4 1.0 1.2 0.7 1.0 1.2 -0.9 1.3 1.1 1.4 1.6 1.2 1.2 1.3 0.8 1.1 1.3 1.1 1.1 0.8 0.8 0.1 0.8 1.5 0.3 0.9 0.5 1.1 0.3 1.0 0.8 1.0
Qualifications: A levels/AS levels or equivalent 0.9 2.0 6.3 0.5 0.9 1.5 1.6 1.0 1.1 1.0 2.1 2.5 1.2 0.8 1.8 1.0 0.8 1.5 2.4 -0.8 2.0 1.4 2.3 1.3 1.6 1.7 1.5 0.9 1.2 1.4 1.2 1.3 -0.0 1.5 0.1 0.8 2.3 1.6 1.5 1.6 1.0 0.2 1.2 1.5 1.1
Serious illness, injury or assault of a close relative in last 2 years 0.5 0.6 2.5 -0.4 -0.8 -0.6 -0.2 -0.5 -0.6 -0.7 -0.3 -0.8 -1.0 -1.2 -0.9 -0.6 0.5 -0.2 -0.1 0.9 -0.3 -0.9 -0.8 -1.6 -0.8 -0.8 -0.7 -0.9 -0.8 -0.7 -0.6 -1.2 -0.0 0.1 1.1 -1.5 -1.0 0.9 0.3 0.7 -0.6 -0.2 0.0 0.7 -0.1
Mouth/teeth dental problems: Dentures 0.6 1.0 2.7 1.5 0.7 1.4 0.0 1.4 1.4 0.6 0.9 0.9 -0.1 -0.0 1.1 0.9 1.3 0.5 0.8 -0.9 1.1 1.6 0.8 0.8 0.8 0.9 1.3 1.2 0.9 1.2 1.0 0.2 0.4 0.7 1.2 0.8 1.1 0.3 1.1 0.6 1.1 1.4 0.9 0.5 1.3
Asthma 0.9 1.7 5.7 -2.0 -1.1 -1.5 -0.2 -2.3 -2.3 -1.1 -0.4 -1.2 -0.8 -0.2 -0.2 -1.0 -1.6 -0.7 -0.8 1.5 -0.5 -1.6 -0.2 -0.7 -0.7 -1.1 -1.0 -1.3 -1.4 -1.1 -1.2 -0.8 -2.2 -1.3 -1.1 -1.7 -1.0 -0.9 -1.6 -1.3 -1.2 -0.7 -2.1 -1.1 -2.4
Medication: Ibuprofen (e.g. Nurofen) 1.1 1.4 3.5 1.1 1.6 1.4 -0.7 0.9 0.8 1.7 0.7 0.5 1.5 -0.2 1.2 1.6 0.7 0.8 1.1 -1.8 1.0 1.9 1.0 0.1 1.5 1.5 1.6 1.7 1.7 1.7 1.6 1.2 1.0 0.7 -0.7 1.1 1.2 -0.2 0.4 0.0 1.8 1.0 0.9 0.1 0.8
Medication: Cholesterol lowering 0.1 0.2 1.0 0.1 0.4 0.2 -0.3 0.2 0.6 0.3 0.5 1.0 0.2 0.2 0.8 0.4 -0.1 0.2 -0.3 -0.6 0.7 0.5 0.6 0.9 0.5 0.6 0.5 0.4 0.6 0.5 0.3 0.3 -0.1 0.2 -0.2 0.1 0.9 -0.4 -0.2 -0.3 0.4 0.2 -0.0 -0.3 -0.0
Depression (self-reported) 0.2 0.2 1.4 0.0 0.5 0.2 1.2 -0.2 -1.0 0.6 0.3 -0.0 -0.2 -0.0 0.3 0.5 -0.3 0.7 0.9 -0.4 0.2 -0.5 0.1 0.2 0.5 0.3 0.3 0.2 0.3 0.3 0.5 -0.2 1.2 0.2 -1.2 -0.1 -0.1 0.0 0.0 0.0 0.5 0.2 0.1 0.3 0.0
Medication: Lansoprazole 2.0 2.2 4.8 1.3 1.4 2.0 0.6 1.7 1.4 1.5 1.7 2.0 0.9 1.1 1.7 1.5 1.4 1.3 2.2 -1.6 1.8 2.1 1.7 1.4 1.9 1.7 1.9 1.5 1.5 1.9 1.7 0.8 0.8 1.1 0.2 1.5 1.8 0.4 1.2 0.8 1.7 1.4 1.4 0.8 1.7
Prospective memory result 2.2 2.7 6.3 -1.4 -1.8 -2.1 -0.4 -1.7 -1.4 -2.0 -1.0 -1.2 -2.5 -1.8 -1.3 -2.1 -2.1 -1.1 -1.9 2.1 -1.8 -2.1 -1.5 -1.3 -1.6 -2.1 -2.0 -2.1 -2.1 -2.0 -1.9 -1.9 -1.1 -0.6 1.1 -2.2 -1.6 0.3 -0.6 -0.1 -2.0 -0.9 -1.4 0.1 -1.4
Lung cancer (father) 0.6 0.7 2.3 0.3 1.0 1.0 0.1 0.4 0.6 1.0 0.9 0.4 1.3 1.0 1.0 0.8 0.1 0.8 0.4 -1.1 0.9 1.5 1.0 0.7 1.0 1.1 1.2 1.0 1.0 1.1 1.0 0.4 0.5 0.4 -0.8 0.9 0.9 0.0 0.3 0.1 1.1 0.0 0.6 0.2 0.4
Illnesses of mother 0.7 0.9 3.9 -0.0 -0.2 -0.8 1.8 -0.2 -0.4 -0.3 -0.2 0.8 -0.6 1.2 -0.9 -0.8 -1.0 0.6 -0.7 0.5 -0.7 -1.6 -0.9 -0.0 -0.6 -0.7 -1.2 -1.0 -0.4 -1.1 -0.5 0.0 1.5 0.7 1.3 -0.7 -0.9 2.0 0.9 1.6 -0.8 0.7 0.5 1.9 0.4
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.3 1.2 0.4 -0.6 -0.6 -0.3 -0.3 0.0 -0.4 -0.9 -0.1 -0.0 -0.4 -1.0 -0.5 -0.3 -0.4 -0.8 0.3 -1.1 -0.8 -0.9 -0.8 -0.8 -0.6 -0.8 -0.7 -0.3 -0.8 -0.5 -0.1 0.4 0.1 1.0 -0.4 -0.6 0.7 0.2 0.6 -0.6 0.6 0.3 0.2 -0.0
Pulse wave Arterial Stiffness index 0.2 0.2 2.0 0.1 0.5 0.2 -0.3 0.2 0.0 0.4 -0.0 -1.4 0.3 -0.5 0.3 0.7 -0.7 0.2 -0.5 -0.4 0.2 -0.1 0.3 -0.1 0.2 0.5 0.4 0.7 0.4 0.5 0.4 0.8 0.4 0.2 -0.7 -0.1 0.3 -0.4 -0.2 -0.3 0.5 -0.3 -0.1 -0.3 -0.1
Impedance of arm (left) 0.3 1.4 5.8 -1.4 -0.5 0.3 -1.2 -1.0 -1.3 -0.3 0.8 0.9 0.3 1.5 1.6 -0.7 -0.8 -0.9 1.2 0.5 0.8 0.2 1.9 0.8 0.3 0.8 0.9 -0.5 -0.5 0.7 -0.3 -0.8 -2.4 -1.4 -1.9 -1.2 1.1 -2.0 -1.3 -1.8 -0.1 -2.1 -1.4 -1.9 -1.2
Arm fat mass (right) 0.6 2.6 7.0 -1.3 -1.8 -1.8 1.6 -1.7 -1.5 -2.1 -0.0 -1.9 -1.7 -2.3 -1.2 -1.6 -2.6 -0.2 -1.7 2.2 -0.8 -2.0 -0.6 -1.3 -1.3 -1.8 -2.0 -2.4 -1.8 -2.0 -1.7 -1.7 -0.7 0.4 1.8 -2.3 -1.2 1.9 0.2 1.3 -2.0 -0.5 -0.5 1.5 -0.9
Trunk predicted mass 0.3 2.0 6.4 -0.7 -0.6 -2.0 1.3 -1.2 -0.1 -0.8 -1.5 -1.6 -1.1 -1.5 -2.2 -0.6 -1.7 0.3 -1.9 0.9 -1.5 -1.4 -2.5 -1.8 -1.3 -2.0 -2.3 -1.2 -0.8 -2.1 -1.0 0.2 1.0 0.5 0.7 -0.2 -2.1 2.4 0.3 1.5 -1.5 0.7 -0.0 1.7 -0.8
Standing height 0.1 0.7 3.5 -0.9 0.2 -1.4 0.4 -1.2 -0.1 0.1 -1.5 -0.8 -0.1 0.0 -1.2 0.1 -1.3 0.2 -1.2 0.2 -0.7 -0.7 -1.9 -0.5 -0.7 -1.1 -1.3 -0.4 -0.3 -1.2 -0.5 0.8 0.4 -0.0 -0.9 0.7 -1.4 1.1 -0.4 0.4 -0.7 0.0 -0.3 0.5 -1.2
Length of working week for main job 0.3 0.3 2.3 -0.2 -0.3 -0.3 0.1 -0.3 -0.3 -0.3 0.5 -0.5 -0.7 -1.5 0.0 -0.1 -1.5 0.5 0.1 0.4 0.1 -0.4 -0.0 -0.7 -0.2 -0.3 -0.3 -0.5 -0.2 -0.3 -0.1 0.1 0.4 0.6 0.2 -1.3 -0.3 0.9 0.5 0.7 -0.3 0.6 0.0 0.5 0.0
Exposure to tobacco smoke at home 0.2 0.2 1.1 -0.6 -0.8 -0.2 -0.2 -0.3 0.5 -0.9 0.4 -0.7 0.1 -0.3 0.3 -1.0 -0.0 -0.4 -0.2 0.7 0.4 0.1 0.7 0.1 -0.5 0.0 -0.2 -0.7 -0.5 -0.3 -0.6 0.0 -0.9 -0.7 0.2 -1.0 0.2 -0.1 -0.2 -0.2 -0.7 -0.1 -0.1 -0.3 -0.3
Breastfed as a baby 0.5 0.6 2.3 -0.1 -0.7 -0.9 -0.3 -0.2 -0.1 -0.6 -1.1 -0.2 -0.1 -0.5 -1.2 -0.9 1.2 -0.9 -0.5 0.6 -1.1 -0.1 -1.5 -0.6 -1.0 -1.2 -1.0 -0.5 -0.9 -0.9 -0.8 -0.5 -0.9 -0.7 1.0 0.5 -0.8 -0.8 -0.6 -0.7 -0.7 -1.0 -0.6 -0.9 -0.3
Tense / ‘highly strung’ 0.3 0.4 2.1 -1.1 -0.2 -0.8 1.0 -1.2 -1.1 -0.1 -0.2 -0.6 -0.5 -1.3 -0.5 0.1 -1.4 0.2 -0.3 0.2 -0.2 -0.4 -0.3 -0.5 -0.4 -0.4 -0.5 -0.4 -0.2 -0.5 -0.2 0.3 -0.4 -0.2 -0.8 0.0 0.0 -0.1 -0.8 -0.4 -0.3 -1.4 -0.7 0.1 -1.2
Seen doctor (GP) for nerves, anxiety, tension or depression 0.8 1.3 5.3 1.0 1.4 0.6 2.2 0.2 0.2 1.5 1.1 0.2 1.4 1.3 0.8 1.4 -0.9 1.9 2.3 -1.3 0.9 0.0 0.5 1.1 1.1 0.7 0.7 0.8 1.3 0.8 1.3 1.9 1.4 1.3 -0.0 1.1 0.7 0.9 0.7 0.8 1.1 1.0 1.0 1.3 0.4
Hair/balding pattern: Pattern 4 0.9 2.1 4.9 -1.3 -1.7 -1.9 -1.1 -1.8 -1.3 -1.8 -1.1 -0.6 -1.1 -1.5 -1.2 -1.7 -1.2 -1.4 -1.4 1.6 -1.6 -1.4 -1.3 -1.0 -1.6 -1.7 -1.8 -2.0 -1.6 -1.7 -1.8 -1.2 -2.2 -1.0 0.0 -1.0 -1.0 -0.3 -1.2 -0.7 -1.9 -1.5 -1.6 -0.7 -1.7
Birth weight of first child 1.9 3.5 7.6 -1.7 -2.1 -2.5 -0.4 -2.0 -1.8 -2.2 -1.9 -0.5 -2.0 -1.8 -2.4 -2.1 -1.0 -1.6 -2.3 2.1 -2.0 -2.1 -2.2 -1.7 -2.3 -2.5 -2.8 -2.3 -2.1 -2.6 -2.3 -1.4 -1.4 -1.2 0.6 -1.5 -2.1 -0.2 -1.4 -0.7 -2.5 -1.3 -1.4 -0.6 -1.8
Peak expiratory flow (PEF) 0.3 0.7 2.3 1.4 0.5 0.7 0.7 0.9 1.1 0.6 0.5 0.1 1.2 0.1 0.3 0.6 1.2 0.7 0.4 -0.7 0.7 0.3 0.5 0.7 0.3 0.5 0.4 0.3 0.8 0.5 0.6 0.6 0.8 1.2 1.5 0.5 0.7 1.0 1.1 1.1 0.5 1.3 1.4 0.9 1.1
Pulse wave reflection index 0.7 0.9 3.0 0.5 1.3 0.9 -0.5 0.6 0.8 1.3 0.0 -0.4 1.1 -0.7 0.7 1.5 0.1 0.3 0.5 -1.4 0.7 1.2 0.5 -0.2 0.9 1.3 1.3 1.6 1.4 1.3 1.2 1.2 0.8 -0.0 -1.7 0.8 1.0 -1.0 -0.3 -0.7 1.4 0.4 0.3 -0.9 0.3
Ever highly irritable/argumentative for 2 days 1.2 1.4 4.2 1.4 0.7 1.5 1.7 1.4 0.8 1.0 2.0 0.9 0.8 1.2 1.2 0.9 0.9 1.3 1.6 -0.8 1.6 0.9 1.6 1.2 1.2 1.0 1.4 1.0 0.8 1.4 1.3 1.0 0.9 1.4 0.7 0.1 1.5 0.6 1.2 0.9 1.2 0.5 1.2 1.2 1.4
Loud music exposure frequency 1.3 1.4 3.5 -0.4 -1.8 -1.6 1.0 -0.8 -0.3 -1.7 -0.2 -0.9 -1.1 -1.5 -1.6 -1.5 0.0 -0.6 -1.0 1.7 -1.0 -1.4 -1.0 -1.0 -1.7 -1.7 -1.7 -1.5 -1.5 -1.7 -1.4 -0.8 -0.9 0.1 1.9 -1.6 -0.9 0.3 -0.4 0.1 -1.7 -0.3 -0.8 0.6 -0.7
Qualifications: O levels/GCSEs or equivalent 0.5 0.8 3.5 -0.1 0.4 0.4 1.6 0.6 0.9 0.1 1.4 1.4 0.4 0.4 0.9 0.4 1.1 1.4 1.3 -0.0 1.2 0.5 1.0 0.9 0.5 0.6 0.3 0.4 0.5 0.2 0.3 0.8 0.9 1.0 1.0 -0.7 0.6 1.6 1.1 1.5 0.1 0.7 0.8 1.9 0.4
Mouth/teeth dental problems: Bleeding gums 0.3 0.4 3.2 -0.4 -0.8 -0.3 -0.2 -0.7 -0.6 -0.7 0.3 -1.2 0.1 -0.7 0.4 -0.7 -0.2 -0.5 -0.1 0.8 0.3 -0.7 0.6 -0.5 -0.5 -0.2 -0.1 -0.9 -0.7 -0.2 -0.6 -0.4 -1.1 -0.6 0.3 -1.8 -0.1 -0.3 -0.3 -0.4 -0.6 -0.4 -0.6 -0.4 -0.6
Blood clot in the leg (DVT) 1.1 1.5 4.5 1.4 1.1 1.7 0.0 1.9 2.1 1.1 1.2 0.4 1.3 0.5 1.3 1.0 0.4 0.8 1.3 -1.1 1.3 1.2 1.4 1.4 1.2 1.2 1.5 1.2 1.1 1.5 1.3 0.5 0.9 1.1 0.7 0.9 1.2 0.4 1.3 0.8 1.3 1.4 1.4 0.7 1.8
Medication: Paracetamol 1.8 3.0 6.4 0.2 -2.1 -1.2 -2.0 -0.4 -0.7 -2.1 -2.1 -2.5 -0.9 -2.5 -2.4 -1.8 -0.7 -2.4 -1.4 1.6 -2.3 -1.6 -2.2 -2.3 -2.2 -1.9 -1.7 -1.6 -1.8 -1.6 -1.7 -2.2 -0.5 -1.7 1.0 -1.5 -2.0 -2.4 -1.5 -2.0 -1.6 -0.3 -1.0 -1.8 -0.4
Headache pain in last month 1.1 1.9 5.2 1.1 1.9 1.7 0.8 1.3 1.2 1.7 1.1 0.4 1.1 -0.4 1.4 2.0 0.9 1.5 1.8 -1.6 1.6 2.3 1.4 0.5 1.6 1.7 1.9 2.0 1.7 1.9 1.9 1.8 1.6 0.8 -0.7 0.9 1.1 -0.2 0.5 0.0 2.0 1.4 0.8 0.6 0.9
Medication for cholesterol, blood pressure or diabetes 1.0 1.6 4.3 -1.5 -1.4 -1.2 -0.3 -1.4 -2.1 -1.3 -0.8 -1.5 -1.1 -0.7 -1.5 -1.1 -1.5 -0.9 -0.5 1.4 -1.6 -1.5 -0.9 -2.1 -1.3 -1.4 -1.4 -1.6 -1.5 -1.4 -1.2 -1.0 -1.1 -1.1 -0.2 -1.1 -1.6 -0.4 -1.0 -0.6 -1.4 -1.5 -1.1 -0.4 -1.2
Glaucoma (self-reported) 0.4 0.5 1.8 0.8 0.8 1.1 -0.3 1.0 0.9 0.8 -0.1 0.3 0.4 0.5 0.5 0.8 0.3 0.1 0.9 -0.7 0.3 0.7 0.4 -0.1 0.7 1.0 1.0 1.0 0.7 1.0 0.8 1.0 1.3 -0.0 -0.1 -0.4 -0.1 -1.2 -0.1 -0.8 1.0 0.9 0.2 -0.7 0.8
Gout (self-reported) 0.3 0.4 1.5 -1.0 -0.6 -0.7 0.6 -0.7 -0.8 -0.7 0.2 -0.8 -0.8 0.2 -0.2 -0.4 -0.4 0.0 -0.3 0.5 -0.1 -0.9 0.2 -0.6 -0.4 -0.3 -0.6 -0.6 -0.4 -0.7 -0.5 -0.1 -0.2 -0.1 -0.2 -1.2 -0.3 0.8 -0.0 0.5 -0.7 -1.1 -0.4 0.8 -0.7
Hypothyroidism/myxoedema (self-reported) 0.1 0.2 1.0 0.1 -0.9 -0.3 -0.7 -0.2 -0.3 -0.9 -0.1 0.3 -0.1 -0.4 -0.3 -0.8 0.1 -0.6 -0.0 0.7 -0.5 -0.6 -0.1 -0.5 -0.6 -0.4 -0.5 -0.9 -0.6 -0.5 -0.7 -1.0 -0.4 -0.4 0.6 -0.3 -0.2 -0.1 0.1 0.0 -0.6 0.3 -0.0 -0.1 0.1
Medication: Amlodipine 2.1 2.9 8.4 1.8 1.6 1.9 0.5 2.2 2.9 1.7 1.1 1.1 1.5 0.3 1.7 1.4 2.7 1.0 1.7 -1.7 1.8 2.2 1.8 2.2 1.8 1.9 1.9 2.2 1.8 1.9 1.7 1.9 1.6 1.7 -0.0 1.1 2.0 1.1 1.6 1.4 1.8 1.2 1.5 0.7 1.8
Medication: Ventolin 100micrograms inhaler 0.4 0.6 1.6 -0.8 -0.8 -0.9 0.1 -1.0 -0.8 -0.5 -0.5 0.6 -0.7 -0.5 -1.0 -0.5 -0.6 -0.5 -0.8 0.9 -0.7 -0.4 -0.7 -0.7 -0.5 -1.1 -0.8 -0.8 -0.9 -0.8 -0.6 -0.7 -1.2 -0.7 -0.2 -0.3 -1.0 -0.7 -0.9 -0.8 -0.7 -0.5 -1.2 -0.5 -0.9
Birth weight 0.3 0.7 7.9 -0.7 -0.3 -1.1 2.1 -1.4 -1.1 -0.2 0.1 0.0 0.4 0.3 -0.2 -0.3 -2.8 0.6 -0.5 0.2 -0.3 -0.9 -0.4 0.2 -0.3 -0.7 -1.0 -0.9 -0.3 -0.9 -0.5 0.4 -0.9 0.5 0.3 0.7 0.2 1.4 0.1 0.8 -0.7 -0.5 -0.2 0.8 -1.0
Chronic bronchitis/emphysema (mother) 0.2 0.2 1.3 -0.0 -0.6 -0.0 0.0 -0.3 -0.6 -0.5 0.4 0.2 -0.2 0.6 0.4 -0.5 -0.8 -0.3 0.4 0.5 -0.1 -0.6 0.5 -0.3 -0.1 -0.2 -0.1 -0.7 -0.5 -0.2 -0.4 -0.3 -0.8 -0.2 0.9 -1.1 0.1 -0.1 0.0 -0.1 -0.4 -0.3 -0.2 -0.1 -0.2
High blood pressure (siblings) 0.1 0.2 0.9 0.0 0.2 -0.1 -0.4 -0.1 0.2 0.2 -0.2 -0.8 0.3 -0.8 0.0 0.3 0.2 -0.1 -0.6 -0.1 -0.0 0.6 0.0 0.7 0.4 0.1 0.1 0.5 0.3 0.1 0.1 0.9 -0.5 -0.0 -0.3 1.0 0.6 0.0 -0.2 -0.1 0.1 -0.8 -0.4 -0.4 -0.6
Forced vital capacity (FVC), Best measure 0.1 0.2 0.9 0.2 -0.2 -0.6 0.2 -0.2 0.4 -0.1 -0.7 0.3 -0.2 -0.3 -0.8 -0.2 0.2 0.0 -0.9 0.0 -0.7 -0.2 -0.9 -0.4 -0.6 -0.5 -0.7 -0.3 -0.0 -0.7 -0.3 0.2 0.6 0.4 0.5 0.1 -0.5 1.0 0.3 0.7 -0.4 0.8 0.4 0.5 -0.2
Body fat percentage 0.4 1.7 5.7 -1.2 -1.5 -1.2 0.7 -1.3 -1.4 -1.8 0.3 -1.8 -1.3 -1.9 -0.4 -1.4 -2.3 -0.4 -1.2 1.9 -0.4 -1.7 -0.0 -0.7 -0.9 -1.2 -1.3 -2.1 -1.6 -1.3 -1.4 -1.8 -0.9 0.1 1.7 -2.4 -0.7 1.1 0.1 0.7 -1.6 -0.4 -0.4 0.8 -0.6
Leg fat percentage (right) 0.5 2.0 6.0 -1.1 -1.6 -1.5 0.2 -1.3 -1.6 -1.9 -0.3 -2.0 -1.4 -2.5 -1.0 -1.4 -2.3 -0.5 -1.5 1.9 -1.0 -1.9 -0.7 -1.3 -1.2 -1.5 -1.6 -2.0 -1.7 -1.6 -1.5 -1.6 -0.7 -0.2 1.7 -2.3 -1.3 0.8 -0.2 0.4 -1.7 -0.3 -0.6 0.6 -0.8
Arm fat-free mass (right) 0.3 1.4 7.7 0.5 0.3 -0.9 1.6 -0.0 0.8 0.0 -0.8 -1.3 -0.0 -1.0 -1.4 0.4 -0.8 1.0 -1.3 -0.0 -0.7 -0.8 -1.9 -0.8 -0.5 -1.1 -1.4 -0.2 0.1 -1.2 -0.1 0.9 2.1 1.4 1.4 0.6 -1.3 2.8 1.2 2.2 -0.5 1.6 1.1 2.3 0.4
Exposure to tobacco smoke outside home 2.7 3.6 10.9 0.6 1.7 1.8 2.9 0.9 1.0 1.6 3.1 0.8 1.5 1.4 2.7 1.6 0.2 2.6 2.0 -1.4 2.9 1.9 3.3 1.8 2.3 2.3 2.0 1.2 1.9 2.0 1.9 2.3 0.8 2.0 -0.3 0.5 2.4 2.5 1.9 2.4 1.6 0.6 1.7 2.4 1.0
Comparative body size at age 10 0.1 0.2 2.0 0.2 -0.3 0.2 -0.8 0.2 0.1 -0.3 0.1 -0.3 0.2 -0.5 0.2 -0.5 -0.1 -0.3 -0.6 0.2 0.0 0.0 -0.1 0.2 -0.1 -0.0 0.0 -0.4 -0.2 0.1 -0.2 -0.8 -0.5 0.3 1.4 -0.4 0.2 -0.2 0.2 -0.0 -0.2 0.9 0.4 -0.1 0.5
Number of full brothers 1.0 1.3 3.2 -0.5 -1.7 -1.0 -0.5 -1.0 -0.8 -1.4 -0.2 -0.7 -0.6 -1.7 -0.8 -1.8 -1.8 -1.1 -0.3 1.6 -0.8 -1.0 -0.7 -1.2 -1.3 -1.3 -1.1 -1.6 -1.5 -1.3 -1.4 -1.4 -1.1 -1.0 0.1 -1.8 -0.8 -0.4 -0.5 -0.4 -1.4 -1.2 -0.8 -0.7 -0.8
Worry too long after embarrassment 1.5 2.5 6.2 2.5 1.5 1.4 1.7 2.2 2.3 1.4 0.9 1.5 2.0 1.0 0.6 1.2 1.8 1.6 0.5 -1.9 1.2 1.3 0.6 1.8 1.1 1.3 1.0 1.6 1.7 1.1 1.5 1.6 2.5 1.4 1.4 2.3 1.5 0.8 1.6 1.2 1.3 1.5 2.2 1.5 2.1
Seen a psychiatrist for nerves, anxiety, tension or depression 1.0 1.3 3.9 0.4 1.7 0.9 1.0 0.2 -0.3 2.0 0.7 1.2 0.9 1.5 0.7 1.9 -0.2 1.4 1.9 -1.8 0.8 1.0 0.6 1.0 1.5 1.0 1.2 1.3 1.5 1.3 1.6 1.5 1.0 0.6 -1.5 2.0 0.7 0.0 0.1 0.0 1.6 0.1 0.5 0.3 0.1
Wheeze or whistling in the chest in last year 0.4 0.7 2.2 -1.2 -0.8 -1.1 0.7 -1.2 -0.9 -1.0 -0.1 -1.5 -0.9 -1.4 -0.7 -0.9 -0.9 -0.1 0.3 1.3 -0.2 -0.8 -0.2 -0.5 -0.7 -0.8 -0.9 -0.9 -0.9 -0.8 -0.7 -0.7 -0.6 -0.6 -0.8 -1.2 -0.7 -0.3 -0.8 -0.5 -0.9 -1.1 -1.2 -0.0 -1.2
Number of children fathered 0.7 0.8 5.3 -0.3 -0.2 0.1 -2.3 -0.4 -0.6 0.0 -0.7 -0.5 0.4 -1.3 0.1 -0.0 0.1 -1.1 0.3 -0.0 -0.4 0.3 0.0 -0.9 0.0 0.2 0.3 0.0 -0.0 0.3 -0.2 -0.1 -0.5 -1.1 -1.3 -0.8 -0.3 -2.2 -1.3 -1.9 0.1 -0.9 -0.9 -2.2 -0.5
Reason for reducing amount of alcohol drunk: Health precaution 1.0 1.1 3.0 0.6 1.1 1.5 -0.1 1.1 1.2 1.4 1.1 0.3 0.6 1.2 1.4 1.4 0.2 0.7 0.3 -1.1 1.3 1.1 1.6 1.2 1.4 1.6 1.7 1.5 1.2 1.6 1.4 1.0 0.3 0.4 -0.6 0.9 1.3 -0.1 0.6 0.2 1.5 0.5 0.8 -0.1 0.8
Age at first live birth 0.3 0.6 2.7 -1.2 -0.7 -0.7 -0.8 -0.9 -0.9 -0.5 -0.5 0.5 -0.0 -0.3 -0.3 -0.5 -0.5 -0.8 -0.8 0.5 -0.2 -0.7 -0.1 -0.5 -0.5 -0.3 -0.4 -0.6 -0.6 -0.4 -0.7 -0.7 -1.7 -0.9 -1.4 -0.3 -0.1 -0.7 -1.0 -0.8 -0.6 -1.6 -0.8 -1.2 -1.0
Pulse wave peak to peak time 0.2 0.2 2.4 0.1 -0.3 -0.1 0.5 0.0 0.2 -0.2 0.1 1.5 -0.1 0.7 -0.2 -0.5 0.8 0.1 0.7 0.2 -0.1 0.2 -0.4 0.2 -0.1 -0.4 -0.4 -0.5 -0.2 -0.4 -0.2 -0.5 -0.2 0.1 0.9 0.5 -0.1 0.7 0.4 0.6 -0.4 0.6 0.4 0.6 0.3
Health satisfaction 1.9 2.5 4.2 1.8 1.7 1.8 1.2 1.8 1.9 2.0 1.4 1.7 1.0 0.2 1.5 1.9 2.0 1.5 1.5 -1.5 1.9 1.5 1.2 1.6 1.5 1.4 1.8 2.0 1.5 1.7 1.8 1.8 1.7 1.8 0.4 0.9 1.4 1.1 1.6 1.3 1.9 1.8 1.5 1.4 1.6
Shortness of breath walking on level ground 0.5 0.6 3.6 -1.1 -0.2 -0.4 -0.8 -0.8 -0.6 -0.4 -0.5 -1.3 -0.6 -1.9 -0.2 -0.3 -0.5 -0.7 0.1 0.2 -0.1 0.4 -0.1 -0.3 -0.0 -0.2 -0.1 -0.1 -0.3 -0.1 -0.3 -0.8 -0.7 -0.8 -1.6 -0.5 -0.1 -1.4 -1.3 -1.4 -0.2 -1.1 -1.1 -1.0 -1.0
Qualifications: College or University degree 0.5 1.7 8.7 0.9 0.9 0.9 1.3 0.6 0.4 1.2 1.6 2.9 1.6 2.0 0.9 1.1 -1.2 1.6 1.2 -1.0 1.0 0.5 1.1 0.8 1.1 1.2 0.9 0.5 1.2 0.8 1.1 1.1 0.5 1.6 0.9 1.8 1.8 2.0 1.6 1.9 0.9 1.0 1.6 1.8 1.1
Eye problems/disorders: None of the above 0.2 0.3 1.6 -0.1 0.2 -0.2 0.7 0.1 0.2 0.2 0.0 -0.7 0.1 0.0 -0.4 0.2 1.0 0.6 -0.4 -0.2 0.1 -0.4 -0.3 0.1 0.1 -0.2 -0.2 0.2 0.1 -0.2 0.1 -0.2 1.3 1.0 -1.1 -0.2 0.0 1.1 0.5 0.9 -0.0 -0.2 0.5 1.0 0.1
Mouth/teeth dental problems: Loose teeth 0.3 0.4 4.1 0.4 -0.7 -0.4 0.4 0.0 0.0 -0.8 0.1 0.2 -1.3 0.0 -0.4 -0.9 -0.5 0.0 -0.4 0.8 -0.2 -0.7 -0.2 -0.4 -0.8 -0.6 -0.6 -0.7 -0.7 -0.6 -0.5 -0.8 0.1 0.0 2.0 -1.0 -0.3 0.5 0.4 0.5 -0.6 0.4 -0.0 0.8 0.2
Emphysema/chronic bronchitis 1.5 1.7 3.8 1.0 1.0 1.3 1.6 1.2 1.7 1.2 2.0 1.5 1.1 0.9 1.4 1.3 1.2 1.6 1.2 -1.0 1.9 1.6 1.6 1.2 1.4 1.2 1.4 1.1 1.1 1.3 1.3 1.0 0.6 1.4 0.9 1.2 1.6 1.3 1.4 1.4 1.2 0.6 1.2 1.7 1.2
Medication for pain relief, constipation, heartburn 0.2 0.4 3.2 -1.1 -0.2 -0.3 1.1 -0.6 -0.4 -0.1 0.9 0.4 -0.1 1.8 0.0 -0.2 -1.2 0.7 -0.2 0.5 0.3 -0.9 0.3 -0.5 -0.0 -0.3 -0.3 -0.5 -0.3 -0.4 -0.2 -0.1 -0.5 0.4 -0.3 -0.1 -0.2 1.0 0.2 0.8 -0.4 -0.6 -0.1 0.9 -0.3
Neck or shoulder pain in last month 0.5 0.7 2.8 1.2 0.7 0.3 1.7 1.1 0.9 0.7 0.1 -0.0 0.6 -0.1 -0.3 0.8 1.5 0.7 -0.0 -0.7 0.2 0.3 0.2 0.7 0.5 0.3 0.2 0.8 0.8 0.3 0.7 0.8 1.6 0.9 0.8 0.9 0.0 1.2 1.1 1.2 0.6 1.0 1.0 1.4 1.2
Medication: Blood pressure 2.2 3.9 9.3 2.4 2.2 2.0 1.0 2.3 3.0 2.1 1.2 1.7 2.0 1.0 2.2 1.9 2.6 1.4 1.5 -2.3 2.1 2.3 1.6 3.0 2.1 2.2 2.1 2.4 2.2 2.1 2.0 1.6 2.0 1.7 -0.2 1.8 2.3 0.8 1.8 1.1 2.2 2.1 1.8 0.7 1.9
Angina (self-reported) 0.5 0.7 2.3 0.8 1.1 0.9 0.1 0.6 0.7 0.9 0.1 0.8 -0.0 -0.1 0.8 1.1 0.3 0.3 0.7 -1.0 0.6 1.5 0.7 0.6 0.8 0.9 1.0 1.1 0.9 1.1 1.0 0.6 0.2 0.1 -0.5 1.5 1.2 -1.4 -0.3 -1.0 1.1 0.0 0.0 -0.8 0.5
Migraine (self-reported) 0.3 0.4 2.6 1.4 0.5 0.8 -0.4 1.1 0.7 0.4 -0.1 -1.0 0.6 0.1 0.0 0.4 0.5 -0.1 -0.2 -0.5 -0.4 0.4 -0.1 -0.4 0.3 0.3 0.6 0.8 0.5 0.6 0.6 0.2 1.6 -0.0 0.9 -0.3 -0.3 -0.8 0.3 -0.4 0.7 1.2 0.7 -0.2 0.9
Medication: Ibuprofen 0.6 0.7 1.7 1.0 0.9 1.1 -0.8 0.6 0.5 1.0 1.0 0.2 1.1 -0.5 1.0 1.0 0.2 0.6 0.9 -1.2 0.8 1.3 0.8 -0.1 1.0 1.1 1.2 0.9 1.1 1.2 1.1 0.4 0.4 0.6 -0.1 0.4 1.1 -0.2 0.4 0.0 1.2 0.8 0.8 0.1 0.7
Medication: Allopurinol 0.6 0.8 2.2 -0.9 -1.3 -1.1 0.3 -0.9 -0.7 -1.3 0.0 -1.0 -1.0 0.1 -0.9 -1.0 -0.4 -0.4 -0.9 1.0 -0.7 -1.5 -0.3 -0.7 -0.9 -0.9 -1.2 -1.3 -0.9 -1.2 -1.1 -1.3 -0.6 0.1 0.7 -1.2 -0.4 0.9 0.0 0.6 -1.3 -0.9 -0.3 0.8 -0.5
Medication: Omeprazole 0.3 0.4 1.3 1.1 0.5 0.7 0.1 0.7 0.6 0.3 0.4 0.5 0.7 -0.4 1.0 0.5 0.3 0.3 1.0 -0.4 0.6 0.5 0.9 0.8 0.6 0.7 0.6 0.4 0.6 0.6 0.4 0.2 0.6 0.3 0.4 -0.2 0.8 0.7 0.9 0.7 0.5 1.1 0.9 0.3 0.7
Medication: Seretide 50 evohaler 0.4 0.5 2.6 -0.6 0.7 0.4 0.7 -0.1 0.4 0.7 0.8 -0.3 -0.4 -0.7 0.9 0.7 0.3 0.7 1.4 -0.2 0.9 1.1 1.4 0.5 0.8 0.9 0.8 0.9 0.6 0.8 0.7 0.7 0.1 -0.1 -1.6 -0.1 0.6 -0.3 -0.3 -0.4 0.7 -0.3 -0.6 0.0 -0.5
Mean time to correctly identify matches 0.2 0.4 2.3 0.5 -0.3 -0.6 -0.0 0.1 -0.0 -0.3 -1.1 -1.1 -0.7 -0.5 -1.5 -0.3 -0.1 -0.3 -0.6 0.5 -1.0 -0.4 -1.4 -0.8 -0.8 -1.0 -0.9 -0.2 -0.4 -0.7 -0.3 0.1 0.5 -0.2 0.4 1.1 -1.2 -0.2 -0.2 -0.2 -0.4 0.0 -0.3 0.1 0.1
Heart disease (mother) 1.3 1.6 4.5 1.1 1.4 1.7 -0.1 1.2 0.9 1.6 1.0 1.4 1.0 0.2 1.4 1.9 0.7 0.7 1.3 -1.6 1.2 2.1 1.9 0.5 1.6 1.6 1.9 1.8 1.5 1.9 1.6 0.9 0.6 0.8 -0.3 1.4 1.4 -0.2 0.6 0.1 1.8 0.6 0.8 -0.2 0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.5 0.7 2.9 0.8 0.7 0.9 0.2 1.0 0.7 0.7 0.6 0.3 0.5 1.4 0.5 0.8 1.5 0.5 1.7 -0.7 0.8 0.9 1.1 0.8 0.8 0.9 0.9 0.8 0.8 0.9 0.9 0.3 0.5 0.6 -0.0 0.5 0.6 0.2 0.7 0.5 0.9 0.8 0.8 0.2 1.0
Whole body fat mass 0.5 2.0 6.8 -1.1 -1.5 -1.6 1.0 -1.5 -1.3 -1.8 -0.1 -1.9 -1.3 -2.1 -0.9 -1.3 -2.6 -0.2 -1.6 1.9 -0.8 -2.0 -0.6 -1.1 -1.1 -1.5 -1.7 -2.1 -1.6 -1.7 -1.5 -1.5 -0.5 0.3 1.8 -2.2 -1.2 1.6 0.2 1.1 -1.8 -0.1 -0.3 1.2 -0.8
Leg fat mass (right) 0.6 2.5 7.3 -1.4 -1.6 -1.8 0.7 -1.7 -1.6 -2.0 -0.5 -2.4 -1.5 -2.5 -1.3 -1.4 -2.7 -0.4 -1.9 2.1 -1.0 -2.1 -0.9 -1.5 -1.3 -1.8 -2.0 -2.2 -1.7 -1.9 -1.7 -1.5 -0.5 -0.1 1.5 -2.4 -1.5 1.3 -0.2 0.7 -2.0 -0.4 -0.6 0.9 -1.1
Arm predicted mass (right) 0.3 1.7 8.9 0.3 0.1 -1.2 1.9 -0.2 0.6 -0.2 -0.8 -1.3 -0.4 -0.9 -1.6 0.2 -0.9 1.1 -1.6 0.3 -0.9 -1.1 -2.0 -1.0 -0.7 -1.4 -1.7 -0.5 -0.1 -1.4 -0.3 0.8 2.0 1.4 1.7 0.4 -1.5 3.0 1.2 2.3 -0.8 1.6 1.0 2.6 0.2
Pulse rate, automated reading 1.7 5.5 10.0 1.7 2.5 2.6 1.0 2.1 2.1 2.5 2.5 2.3 2.8 3.1 2.8 2.5 2.2 2.3 2.1 -2.5 2.9 1.7 2.7 3.2 2.7 2.5 2.7 2.1 2.4 2.7 2.5 2.1 1.8 2.4 0.3 1.7 2.2 1.8 2.3 2.0 2.6 2.7 2.3 1.6 2.4
Alcohol intake frequency. 0.2 0.4 3.3 0.2 -0.5 -0.2 1.1 -0.2 -0.4 -0.6 0.5 -0.7 -0.8 -0.2 0.2 -0.4 -1.6 -0.1 0.3 0.6 -0.2 -1.0 0.3 0.0 -0.3 -0.4 -0.3 -0.9 -0.5 -0.4 -0.4 -0.7 -0.3 0.8 1.8 -1.0 -0.0 0.6 0.6 0.6 -0.5 0.6 0.0 0.6 0.3
Comparative height size at age 10 0.2 1.0 3.6 -0.9 -0.7 -1.3 0.2 -0.8 0.3 -0.6 -1.6 -1.5 -0.8 -0.4 -1.5 -1.0 -0.7 -0.7 -1.9 0.8 -0.8 -0.8 -1.5 -1.2 -1.3 -1.2 -1.4 -0.6 -0.9 -1.3 -0.9 -0.1 0.4 -0.6 -0.6 -1.1 -1.8 -0.2 -0.9 -0.5 -1.1 -0.3 -0.6 -0.6 -1.0
Number of full sisters 0.4 0.5 1.6 0.3 0.5 0.7 1.1 0.4 0.6 0.5 1.2 0.4 0.4 0.5 1.0 0.4 0.3 0.8 0.9 -0.3 1.1 0.6 1.3 0.9 0.9 0.6 0.8 0.4 0.5 0.7 0.7 0.9 0.3 0.6 0.3 -0.4 0.7 0.7 0.7 0.7 0.6 0.5 0.6 0.6 0.4
Suffer from ‘nerves’ 0.2 0.4 1.9 0.1 1.0 0.2 0.3 0.0 0.0 1.1 -0.4 -0.8 0.3 -1.0 -0.0 1.0 0.1 0.5 0.1 -1.1 0.1 0.5 -0.2 0.5 0.7 0.4 0.4 0.8 0.9 0.4 0.7 0.9 0.8 0.3 -0.6 1.4 0.0 0.3 0.1 0.2 0.8 0.3 0.4 0.5 -0.1
Overall health rating 0.1 0.2 2.2 -0.3 -0.3 0.3 -0.1 -0.1 0.1 0.0 0.4 -0.2 -0.6 -0.8 0.5 -0.2 0.7 -0.3 1.5 0.3 0.8 0.3 0.9 0.9 0.5 0.2 0.5 0.0 -0.1 0.3 0.0 -0.4 -0.4 0.4 -0.1 -1.1 0.5 0.4 0.2 0.3 0.1 -0.1 -0.0 0.2 -0.2
Chest pain or discomfort 4.1 6.0 10.8 2.4 2.5 2.8 2.2 2.5 2.5 2.5 2.8 3.3 1.8 1.7 2.9 2.5 2.2 2.6 3.1 -2.2 3.1 3.0 2.6 2.5 2.8 2.4 2.8 2.6 2.3 2.7 2.6 2.6 1.7 2.5 0.8 1.7 2.7 1.5 2.3 1.9 2.6 1.7 2.2 2.1 2.2
Had major operations 0.1 0.2 1.9 0.0 0.2 0.1 0.2 -0.1 0.1 0.2 0.5 -0.2 0.3 1.2 0.1 0.4 -0.7 0.3 0.6 -0.3 0.0 0.3 0.4 0.4 0.3 0.3 0.2 0.3 0.3 0.3 0.4 0.0 -0.4 0.1 0.2 1.4 0.7 0.3 0.1 0.2 0.3 0.1 -0.0 0.3 -0.1
Age at last live birth 1.8 2.6 8.4 -2.0 -2.0 -1.7 -1.4 -2.0 -1.3 -1.8 -0.8 -1.6 -1.1 -1.1 -0.9 -1.9 -1.4 -1.7 -1.4 1.9 -1.0 -1.6 -0.8 -1.5 -1.6 -1.4 -1.5 -1.8 -1.8 -1.6 -1.8 -1.7 -2.9 -1.6 -1.0 -1.4 -0.7 -1.3 -1.7 -1.5 -1.8 -2.2 -1.8 -1.7 -2.0
Family relationship satisfaction 1.7 2.1 7.3 0.4 1.4 0.9 2.2 0.6 1.0 1.5 1.9 0.9 0.6 1.7 1.2 1.2 -0.1 2.2 1.7 -1.5 1.5 0.8 1.4 1.2 1.4 1.2 1.0 1.1 1.6 1.1 1.4 1.9 1.5 2.3 -0.0 1.0 1.4 2.7 1.6 2.4 1.2 1.0 1.5 2.3 0.8
Leg pain on walking 0.2 0.3 2.2 1.0 0.2 0.3 0.3 0.9 0.9 0.4 -0.1 0.3 0.9 0.6 -0.2 0.2 0.2 0.1 -0.2 -0.6 -0.1 0.5 -0.4 0.9 0.2 -0.0 0.1 0.8 0.4 0.1 0.4 0.3 0.5 0.1 1.5 0.9 0.0 -0.1 0.4 0.1 0.5 0.8 0.7 0.1 0.6
Qualifications: NVQ or HND or HNC or equivalent 1.8 2.2 5.2 -2.0 -1.1 -1.3 -1.5 -1.5 -1.4 -1.1 -1.3 -1.2 -1.5 -0.9 -1.1 -1.2 -2.0 -1.6 -0.6 1.0 -1.5 -0.7 -1.0 -1.8 -1.1 -0.9 -0.9 -0.7 -1.1 -1.0 -1.2 -0.9 -1.2 -2.1 -2.3 -1.5 -1.4 -2.0 -2.1 -2.1 -1.1 -1.9 -2.1 -2.1 -2.0
Commuting to job workplace: Car/motor vehicle 0.5 0.6 2.6 -0.7 -0.7 -0.8 -0.1 -0.7 -0.5 -0.8 -0.7 -1.1 -1.5 -1.6 -0.9 -0.7 -0.2 -0.4 -0.4 0.9 -0.7 -0.7 -0.8 -0.9 -0.8 -0.9 -0.8 -0.5 -0.8 -0.8 -0.7 -0.4 -0.3 -0.3 -0.0 -1.3 -1.0 -0.2 -0.6 -0.4 -0.7 -0.5 -0.8 -0.3 -0.9
Illness, injury, bereavement, stress in last 2 years 0.6 0.7 3.1 -0.6 -0.6 -1.0 0.1 -0.4 -0.3 -0.9 -1.1 -0.4 -1.1 0.9 -1.2 -0.9 0.4 -0.5 -1.8 0.9 -0.9 -0.8 -1.7 -0.5 -1.1 -1.2 -1.4 -0.6 -0.9 -1.3 -1.0 -0.5 -0.2 -0.5 0.2 1.0 -1.2 -0.3 -0.5 -0.4 -1.0 0.1 -0.4 -0.1 -0.5
Medication: Aspirin 0.6 0.9 4.3 0.7 1.0 0.9 -0.2 0.7 1.2 1.0 0.0 0.4 0.0 -0.5 1.1 1.1 1.9 0.2 0.6 -1.1 0.8 1.7 0.6 2.1 1.1 1.1 1.1 1.2 1.0 1.1 0.9 0.8 0.3 0.1 -0.6 1.2 1.2 -0.4 0.3 -0.2 1.1 0.1 0.3 -0.5 0.4
Supplements: Vitamin C 0.5 0.5 4.7 -1.3 -0.3 -0.5 -0.3 -0.8 -0.4 -0.3 0.1 -1.1 -1.1 -2.2 0.3 -0.1 -0.2 -0.2 -0.9 0.3 0.5 0.7 0.6 0.1 -0.1 0.1 0.0 -0.0 -0.3 -0.1 -0.3 -0.3 -1.5 -0.6 -1.2 -0.3 0.3 -0.9 -1.0 -1.0 -0.2 -0.5 -0.9 -0.8 -1.2
Knee pain experienced in last month 0.5 0.8 1.7 -0.6 -1.0 -0.9 -1.1 -1.0 -0.9 -1.0 -1.1 -1.0 -0.8 -1.0 -0.7 -1.0 -1.0 -1.1 -1.1 1.0 -1.1 -0.5 -0.6 -0.8 -0.9 -0.8 -0.8 -0.8 -0.9 -0.9 -0.9 -0.6 -0.7 -1.3 0.2 -1.2 -1.2 -0.7 -0.8 -0.9 -0.9 0.1 -0.9 -1.0 -1.0
Hypertension (Self-reported) 5.1 14.1 31.9 4.0 4.1 3.6 2.8 4.5 5.7 4.0 2.5 3.8 3.9 1.9 3.1 3.9 5.1 3.4 2.1 -4.0 3.9 4.8 2.4 4.6 3.5 3.6 3.5 4.9 4.0 3.6 3.9 4.2 3.7 3.5 1.0 4.7 3.9 2.9 3.8 3.2 3.9 3.2 3.9 2.7 3.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.5 0.5 1.4 -0.0 -0.9 -0.5 -0.7 -0.3 -0.6 -1.0 -0.8 -0.2 -0.0 -1.2 -1.0 -0.7 -0.6 -0.8 -0.4 0.9 -0.9 -0.9 -1.0 -0.3 -0.9 -0.9 -1.0 -1.2 -1.0 -0.9 -0.8 -1.1 -0.3 -0.8 0.8 -0.3 -0.7 -0.7 -0.5 -0.6 -0.9 0.0 -0.3 -0.5 -0.0
Illnesses of father: Heart disease 0.2 0.3 1.0 0.6 0.4 0.9 -0.8 0.4 0.5 0.4 0.3 -0.5 0.9 -0.5 0.9 0.7 0.3 -0.4 0.2 -0.6 0.4 0.4 0.9 0.4 0.7 0.7 0.9 0.5 0.6 0.9 0.5 -0.0 0.2 -0.6 -0.3 -0.4 0.3 -0.9 -0.0 -0.6 0.6 0.1 0.2 -1.0 0.5
Illnesses of siblings: Diabetes 0.6 0.8 6.4 1.0 -0.7 -0.3 1.0 0.1 0.3 -0.9 0.1 -0.8 -0.6 -1.0 -0.7 -1.0 -0.2 0.2 0.2 0.5 -0.7 -0.6 -0.8 0.0 -0.5 -0.7 -0.8 -1.0 -0.4 -0.8 -0.5 0.1 0.6 0.9 2.5 -0.2 -0.2 1.8 1.2 1.6 -0.7 0.6 0.8 1.6 0.6
Smoking status: Previous 0.3 0.4 1.6 -1.0 -0.5 -0.9 0.2 -1.3 -0.5 -0.6 -0.4 -0.7 -0.2 0.8 -0.3 -0.5 -1.1 -0.3 0.2 0.4 -0.4 -0.2 -0.3 -0.7 -0.2 -0.5 -0.8 -0.8 -0.3 -0.7 -0.7 -0.4 -0.6 -0.4 -1.2 -0.2 -0.4 0.6 -0.4 0.2 -0.7 -0.6 -0.7 0.1 -1.1
Forced expiratory volume in 1-second (FEV1), predicted 0.6 1.2 4.8 -1.9 -0.1 -1.3 0.8 -1.5 -1.2 -0.4 -1.2 -1.3 -1.7 -0.3 -1.3 -0.4 -1.8 0.2 -1.0 0.9 -0.8 -0.9 -1.2 -1.7 -0.9 -0.9 -1.1 -0.5 -0.7 -1.1 -0.6 -0.1 1.1 -0.7 -1.5 -1.7 -2.2 0.6 -0.9 -0.0 -0.8 -0.5 -1.0 0.5 -1.7
Whole body fat-free mass 0.3 1.6 5.8 -0.6 -0.5 -1.6 1.6 -1.0 0.0 -0.7 -1.0 -1.6 -0.9 -1.4 -1.8 -0.4 -1.6 0.5 -1.8 0.9 -1.0 -1.3 -2.1 -1.4 -1.1 -1.7 -2.0 -1.1 -0.7 -1.8 -0.8 0.1 1.1 0.7 1.0 -0.4 -1.8 2.4 0.5 1.7 -1.3 0.7 0.2 1.9 -0.5
Leg fat-free mass (right) 0.2 0.9 5.1 -0.4 -0.2 -0.9 2.0 -0.5 0.2 -0.5 -0.1 -1.4 -0.3 -1.1 -0.8 -0.1 -1.3 0.8 -1.3 0.7 -0.1 -0.8 -0.9 -0.6 -0.5 -1.0 -1.2 -0.9 -0.5 -1.1 -0.5 0.1 0.9 1.0 1.2 -0.6 -0.9 2.2 0.8 1.7 -0.8 0.7 0.4 2.0 -0.0
Arm fat percentage (left) 0.4 1.6 6.7 -1.2 -1.5 -1.0 1.5 -1.2 -1.4 -1.8 0.8 -1.6 -1.2 -1.7 -0.1 -1.4 -2.2 -0.1 -0.9 1.9 -0.0 -1.5 0.6 -0.7 -0.7 -0.9 -1.1 -2.1 -1.5 -1.1 -1.3 -1.8 -0.8 0.4 1.6 -2.6 -0.4 1.4 0.3 1.0 -1.5 -0.5 -0.4 1.2 -0.5
Average weekly red wine intake 0.4 0.6 2.8 0.7 0.6 0.3 1.5 0.5 0.6 0.6 0.6 1.0 0.2 1.2 0.2 0.8 0.0 1.1 0.4 -0.7 0.7 0.6 0.3 0.1 0.7 0.5 0.3 0.3 0.6 0.3 0.6 0.7 0.8 1.0 1.1 0.9 0.6 1.7 1.1 1.5 0.5 0.4 0.9 1.5 0.8
Handedness (chirality/laterality): Left-handed 4.7 5.7 10.8 -2.8 -2.0 -2.1 -2.5 -2.6 -3.3 -2.1 -2.5 -1.8 -2.5 -2.5 -1.8 -1.9 -2.8 -2.7 -2.1 2.2 -2.5 -1.8 -1.7 -2.9 -2.0 -1.9 -1.9 -2.3 -2.2 -1.9 -2.2 -2.7 -2.1 -2.9 -1.6 -2.6 -2.6 -2.6 -2.8 -2.8 -2.0 -1.9 -2.9 -2.7 -2.7
Mood swings 0.4 0.7 2.2 -0.9 -0.7 -1.1 -0.3 -1.4 -1.5 -0.7 -0.7 -0.8 -0.2 -1.2 -0.6 -0.6 -1.2 -0.6 -0.4 0.7 -0.6 -0.8 -0.4 -0.5 -0.7 -1.0 -0.9 -1.0 -0.7 -0.9 -0.8 -0.5 -0.7 -0.7 -0.9 -0.8 -0.5 -0.2 -0.9 -0.5 -0.9 -1.2 -1.1 -0.2 -1.4
Loneliness, isolation 0.5 0.7 2.2 -1.3 -0.9 -1.1 0.4 -1.1 -1.1 -0.7 -0.3 -1.4 -0.6 -1.5 -0.9 -0.6 -0.4 -0.2 -0.3 0.8 -0.6 -1.2 -0.6 -1.0 -0.7 -1.0 -0.9 -0.9 -0.9 -0.9 -0.7 -0.4 -0.5 -0.3 -0.5 -0.9 -0.9 0.0 -0.7 -0.3 -0.9 -1.3 -0.9 0.1 -1.1
Long-standing illness, disability or infirmity 0.1 0.2 1.3 0.6 0.0 0.4 -0.1 0.5 0.4 0.1 0.4 0.3 0.5 0.5 0.5 -0.1 0.5 -0.0 1.1 -0.1 0.4 0.2 0.5 0.7 0.6 0.3 0.5 0.2 0.1 0.4 0.2 -0.1 -0.1 0.6 0.4 -0.3 0.6 0.1 0.5 0.2 0.3 1.1 0.4 -0.0 0.5
Ever had bowel cancer screening 0.1 0.1 1.3 0.2 0.0 -0.1 0.5 0.1 -0.2 -0.1 0.1 1.1 -0.2 0.3 -0.1 0.0 -0.7 0.2 -0.3 -0.2 -0.1 -0.0 -0.3 0.0 0.0 -0.1 -0.3 -0.2 0.2 -0.3 -0.1 -0.3 0.6 0.4 0.5 0.4 -0.1 0.5 0.4 0.4 -0.1 0.3 0.4 0.3 0.4
Diabetes diagnosed by doctor 0.5 0.8 2.8 1.6 0.6 1.5 -0.9 1.6 0.6 0.6 0.6 0.5 1.0 -1.0 0.8 0.6 0.7 0.2 0.9 -0.6 0.5 0.6 0.6 0.5 0.7 1.0 1.2 0.7 0.6 1.1 0.9 0.2 1.1 0.7 1.1 0.1 0.9 -0.1 1.0 0.4 1.0 1.4 1.3 -0.1 1.7
Ever had stillbirth, spontaneous miscarriage or termination 1.7 1.8 11.4 -1.5 -1.6 -1.0 -1.4 -1.8 -1.7 -1.1 -0.1 -0.9 -0.0 0.1 -0.3 -1.3 -3.4 -1.3 -0.1 1.4 -0.8 -1.5 -0.1 -0.8 -0.8 -0.8 -0.6 -1.7 -1.3 -0.8 -1.2 -1.0 -3.1 -1.5 -0.6 -1.3 -0.2 -1.4 -1.4 -1.5 -1.1 -1.7 -1.5 -1.8 -1.5
Friendships satisfaction 0.2 0.3 1.4 -1.1 -0.2 -0.7 0.4 -0.9 -0.7 -0.0 -0.3 0.1 -1.2 -0.3 -0.5 -0.3 -0.8 0.2 -0.4 0.4 -0.2 -0.7 -0.5 0.1 -0.5 -0.6 -0.5 -0.2 -0.4 -0.5 -0.3 0.2 -0.6 0.2 -0.8 0.3 -0.2 0.4 -0.5 0.0 -0.3 -0.6 -0.7 0.4 -0.9
Qualifications: nursing, teaching 0.4 0.6 2.3 -0.0 0.8 0.5 1.2 0.4 0.3 0.8 1.0 0.9 0.1 0.6 0.5 1.1 0.2 1.2 0.2 -0.6 0.9 0.6 0.7 -0.0 0.7 0.8 0.5 0.6 0.8 0.6 0.8 0.1 0.8 0.8 -0.2 0.9 0.5 1.3 0.9 1.2 0.7 0.3 0.9 1.5 0.5
Commuting to job workplace: Walk 0.3 0.3 1.3 -0.7 0.0 -0.1 -1.1 -0.2 -0.5 -0.1 -0.7 -0.5 0.0 -0.7 -0.1 0.1 -0.6 -0.7 -0.5 0.4 -0.2 0.4 -0.1 -0.3 -0.0 0.1 0.2 0.2 -0.3 0.2 -0.1 -0.3 -0.5 -0.6 -0.8 -0.0 -0.4 -0.9 -0.6 -0.8 0.1 -1.0 -0.8 -1.1 -0.3
Eye problems/disorders: Cataract 0.3 0.3 1.4 0.7 0.4 0.6 -1.2 0.5 0.4 0.4 -0.4 1.1 0.2 0.9 0.4 0.4 0.3 -0.4 0.0 -0.5 0.1 1.1 0.3 0.6 0.2 0.6 0.6 0.5 0.5 0.6 0.3 0.0 -0.4 -0.6 0.5 1.1 0.4 -0.8 0.0 -0.5 0.6 0.2 0.1 -0.7 0.5
Mouth/teeth dental problems: Mouth ulcers 0.7 1.0 6.0 1.0 1.1 0.4 2.5 0.8 0.8 1.0 0.6 0.3 0.7 1.7 0.2 0.8 0.7 1.5 0.4 -0.8 0.9 0.5 0.2 1.3 0.8 0.5 0.4 0.8 0.9 0.4 0.9 1.4 1.4 1.4 0.4 0.9 0.5 1.6 1.1 1.5 0.7 0.8 1.2 1.5 0.8
Medication for cholesterol 1.6 2.4 10.6 -1.5 -1.5 -1.8 -0.1 -1.9 -2.3 -1.5 -0.9 -1.2 -2.0 0.9 -1.4 -1.5 -2.6 -0.6 -1.8 1.3 -1.3 -3.3 -1.4 -1.6 -1.6 -1.6 -1.8 -2.1 -1.4 -1.9 -1.6 -1.7 -0.6 -0.8 0.4 -2.3 -2.0 0.6 -0.7 0.1 -1.8 -0.5 -0.8 0.5 -1.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.0 1.2 3.8 1.1 0.7 0.6 1.6 0.9 1.4 0.7 0.5 1.6 1.2 1.0 0.2 0.7 2.0 1.1 0.5 -0.8 1.0 1.0 0.1 1.7 0.3 0.4 0.3 0.6 0.7 0.4 0.7 0.9 1.1 1.1 1.1 1.6 0.7 1.8 1.4 1.7 0.5 1.2 1.4 1.9 1.1
Back pain experienced in last month 0.2 0.3 3.1 0.4 -0.1 0.1 0.9 0.4 0.6 -0.1 0.5 -0.3 0.0 -1.8 0.4 -0.2 0.5 0.3 0.8 0.3 0.4 0.2 0.7 0.0 0.0 0.1 -0.0 0.1 -0.0 0.1 0.0 0.3 0.2 0.5 0.9 -0.8 0.1 0.3 0.4 0.3 -0.0 1.3 0.3 0.5 0.3
Mineral and other dietary supplements 0.3 0.4 2.7 -0.4 -0.8 -0.4 0.2 -0.7 -0.4 -0.7 0.3 1.2 -0.2 0.3 -0.0 -0.7 -0.5 -0.2 0.4 1.1 -0.2 -0.3 0.1 -0.0 -0.6 -0.6 -0.6 -1.2 -0.9 -0.6 -0.7 -0.4 -1.6 -0.3 0.1 -0.1 0.3 0.4 0.1 0.3 -0.8 -0.9 -0.5 0.1 -0.3
Breast cancer (self-reported) 0.8 1.0 3.1 -0.0 0.6 1.1 1.2 0.5 0.8 0.8 1.6 0.9 0.3 1.5 1.1 0.7 0.4 0.9 1.1 -0.6 1.4 1.3 1.8 1.4 1.1 1.0 1.1 0.5 0.7 1.1 0.9 0.6 -0.2 1.3 -0.4 0.6 1.6 0.9 0.8 1.0 0.9 -0.7 0.8 0.8 0.7
Asthma (self-reported) 0.8 1.6 5.7 -2.0 -1.0 -1.6 0.0 -2.3 -2.2 -1.0 -0.2 -1.0 -0.6 -0.1 -0.1 -0.9 -1.7 -0.5 -0.7 1.5 -0.4 -1.5 -0.1 -0.5 -0.6 -1.1 -1.0 -1.3 -1.4 -1.1 -1.1 -0.7 -2.3 -1.1 -0.9 -1.5 -0.8 -0.7 -1.4 -1.2 -1.2 -0.7 -2.0 -0.9 -2.4
Osteoporosis (self-reported) 0.6 0.7 3.5 0.0 -1.1 -0.9 0.8 -0.2 0.1 -1.2 -0.2 -0.3 -1.0 -0.9 -1.2 -0.9 0.5 0.1 -0.7 1.1 -0.3 -1.1 -1.1 -0.5 -1.0 -1.3 -1.3 -1.0 -1.0 -1.3 -0.9 -0.6 -0.4 0.3 1.9 -0.3 -0.7 0.7 0.1 0.5 -1.2 0.0 -0.1 0.7 -0.2
Osteoarthritis (self-reported) 0.5 0.6 2.4 -0.0 -0.9 -0.3 -0.8 -0.1 0.0 -0.9 -0.5 -0.7 -0.8 -0.9 -0.3 -0.8 -0.6 -1.1 -0.5 0.9 -0.6 -0.6 -0.5 -0.7 -0.8 -0.7 -0.4 -0.6 -0.9 -0.5 -0.8 -0.9 -0.7 -1.1 1.4 -1.6 -1.2 -1.3 -0.6 -1.1 -0.6 0.5 -0.6 -1.3 -0.2
Medication: Aspirin 0.9 1.2 4.5 0.7 1.1 1.2 -0.1 0.9 1.6 1.1 0.5 0.8 0.3 0.0 1.4 1.2 2.1 0.4 1.0 -1.2 1.1 1.9 1.0 2.1 1.2 1.4 1.4 1.3 1.1 1.4 1.0 0.9 0.3 0.2 -0.7 1.1 1.6 -0.4 0.4 -0.2 1.2 -0.1 0.4 -0.5 0.6
Medication: Gliclazide 0.3 0.3 1.5 0.2 0.0 0.5 0.0 0.3 0.4 0.0 0.9 1.0 -0.5 0.0 1.0 0.0 0.0 0.2 0.6 -0.0 0.6 0.3 1.1 0.7 0.4 0.5 0.6 0.0 -0.0 0.4 0.2 -0.1 0.1 0.6 0.6 -1.2 0.9 1.0 0.8 0.9 0.1 -0.4 0.5 0.5 0.4
Illnesses of father: None of the above (group 1) 0.3 0.4 3.6 0.2 0.1 -0.3 0.9 0.1 -0.3 -0.1 0.1 1.9 0.4 1.1 -0.6 -0.1 0.2 0.8 0.1 0.0 -0.2 -0.3 -0.5 -0.0 -0.4 -0.4 -0.6 -0.4 0.0 -0.4 -0.0 -0.1 0.7 0.9 1.1 1.0 -0.2 1.0 0.5 0.9 -0.2 1.0 0.6 1.4 0.5
Smoking status: Current 0.4 0.6 2.2 -0.8 0.3 0.4 -0.5 -0.6 -0.4 0.5 0.6 -0.9 0.2 -0.6 1.1 0.4 -0.8 -0.1 1.3 -0.3 0.5 0.8 1.1 0.5 0.9 0.9 0.9 0.2 0.4 0.8 0.4 0.7 -0.9 -0.6 -1.5 -0.6 0.6 -1.3 -0.9 -1.2 0.5 -0.5 -0.8 -1.1 -0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.4 2.9 1.3 0.3 0.5 0.2 0.8 0.3 0.3 0.3 0.9 0.2 0.3 0.4 0.3 1.3 0.3 0.3 -0.3 0.2 0.2 0.7 0.4 0.1 0.4 0.4 0.3 0.4 0.4 0.4 0.6 0.4 0.9 1.7 -0.0 0.5 0.2 0.7 0.4 0.4 1.4 0.6 -0.0 0.9
Whole body water mass 0.3 1.7 6.3 -0.5 -0.4 -1.6 1.7 -0.9 0.1 -0.7 -1.0 -1.5 -0.9 -1.4 -1.8 -0.4 -1.6 0.6 -1.8 0.9 -1.0 -1.3 -2.1 -1.4 -1.1 -1.7 -2.0 -1.1 -0.7 -1.8 -0.8 0.2 1.1 0.8 1.0 -0.3 -1.8 2.5 0.6 1.8 -1.3 0.8 0.2 2.0 -0.5
Leg predicted mass (right) 0.2 1.0 4.8 -0.4 -0.3 -0.9 1.9 -0.6 0.2 -0.5 -0.2 -1.3 -0.3 -1.1 -0.9 -0.2 -1.4 0.8 -1.3 0.7 -0.2 -0.9 -1.0 -0.7 -0.6 -1.1 -1.3 -0.9 -0.5 -1.2 -0.5 0.0 0.9 1.0 1.2 -0.6 -1.0 2.2 0.8 1.7 -0.9 0.7 0.4 1.9 -0.1
Arm fat mass (left) 0.5 2.2 6.4 -1.2 -1.6 -1.5 1.7 -1.4 -1.3 -1.9 0.2 -1.7 -1.5 -2.0 -0.9 -1.4 -2.5 -0.0 -1.6 2.0 -0.6 -1.9 -0.3 -1.1 -1.1 -1.6 -1.7 -2.2 -1.6 -1.7 -1.5 -1.5 -0.5 0.6 1.8 -2.2 -0.9 2.0 0.4 1.4 -1.8 -0.3 -0.3 1.6 -0.7
Number of self-reported non-cancer illnesses 0.1 0.1 0.7 0.3 0.4 0.1 -0.1 0.2 0.5 0.3 0.0 -0.8 0.3 -0.2 0.3 0.3 0.5 0.2 -0.1 -0.1 0.4 0.5 -0.2 0.4 0.3 0.0 0.2 0.7 0.2 0.2 0.3 0.3 0.2 0.1 0.2 0.2 -0.0 -0.4 -0.1 -0.3 0.4 0.8 -0.1 -0.3 -0.2
Average weekly champagne plus white wine intake 0.5 0.7 3.7 1.0 0.3 0.5 1.1 1.1 1.5 0.4 0.6 0.7 1.1 0.7 -0.0 0.4 1.0 0.9 0.2 -0.5 0.6 0.3 0.3 0.6 0.3 0.2 0.3 0.5 0.5 0.3 0.5 0.3 0.8 1.1 1.9 0.8 0.4 1.2 1.2 1.3 0.4 0.6 1.3 1.3 1.1
Miserableness 0.1 0.2 2.2 0.8 0.3 0.4 -0.1 0.4 -0.0 0.5 -0.1 -0.1 1.5 -1.3 -0.2 0.3 -0.2 0.1 1.0 -0.4 0.0 0.3 0.1 0.0 0.4 0.3 0.3 0.3 0.5 0.3 0.4 0.3 1.2 0.4 0.4 0.3 0.2 0.0 0.3 0.2 0.4 0.3 0.5 0.2 0.5
Guilty feelings 0.7 1.1 6.3 1.2 0.9 0.0 2.3 0.6 0.4 0.9 -0.2 -0.5 0.3 0.5 -0.8 0.9 0.6 1.3 1.0 -0.8 0.1 -0.2 -0.9 1.0 0.4 -0.2 -0.2 0.6 0.8 -0.1 0.7 1.1 1.6 1.1 0.6 2.5 -0.0 2.0 1.2 1.7 0.5 0.7 1.3 2.2 0.8
Wears glasses or contact lenses 0.1 0.1 1.3 -0.0 0.2 0.2 0.4 0.2 0.1 0.2 0.3 -1.1 -0.2 -0.4 0.1 0.3 0.7 0.2 0.3 -0.1 0.4 0.2 0.1 0.1 0.3 0.1 0.3 0.3 0.2 0.3 0.2 -0.2 0.4 0.3 0.3 -0.2 -0.4 0.2 0.2 0.2 0.3 0.1 0.1 0.3 0.2
Ever taken oral contraceptive pill 1.5 1.7 4.6 -1.0 -1.5 -1.1 -2.1 -1.3 -1.4 -1.4 -1.0 -1.6 -0.1 -0.9 -0.6 -1.6 -1.4 -1.9 0.3 1.0 -1.4 -1.1 -0.6 -1.0 -1.1 -0.8 -0.9 -1.5 -1.1 -1.0 -1.5 -1.8 -1.7 -1.5 -1.0 -1.2 -0.5 -1.5 -1.3 -1.5 -1.3 -2.1 -1.2 -1.7 -1.2
Hearing aid user 0.7 0.8 2.7 1.1 0.7 0.7 1.1 1.1 0.8 0.8 0.8 -0.3 0.6 -0.6 0.6 0.6 1.2 1.0 0.9 -0.7 0.8 0.5 0.4 0.4 0.8 0.4 0.7 1.1 0.7 0.6 0.8 0.6 0.8 1.3 1.6 0.6 0.3 1.4 1.3 1.3 0.8 1.6 1.0 1.4 0.9
Mother’s age at death 0.8 0.9 2.3 0.3 1.4 1.0 0.3 0.5 0.9 1.4 0.7 0.7 0.2 0.3 1.2 1.5 0.3 0.9 1.0 -1.3 1.1 1.1 0.8 1.0 1.4 1.2 1.2 1.2 1.3 1.3 1.2 1.4 0.2 0.6 -0.9 1.5 1.0 0.6 0.6 0.5 1.3 0.2 0.7 0.2 0.4
Financial situation satisfaction 0.8 1.0 3.7 -0.0 -0.8 -1.2 -0.2 -0.5 -0.4 -1.0 -1.3 0.1 -0.5 -0.1 -1.5 -1.1 -0.5 -0.8 -1.9 0.7 -1.7 -1.4 -1.8 -0.6 -1.2 -1.4 -1.5 -0.8 -0.8 -1.3 -1.0 -0.6 0.1 -0.8 0.6 -0.5 -1.5 -0.9 -0.9 -0.9 -1.1 0.4 -0.5 -0.8 -0.6
Tinnitus: Yes, now most or all of the time 0.6 0.7 2.4 1.2 0.6 1.0 -0.3 1.5 1.5 0.7 0.8 0.5 1.3 0.2 0.5 0.6 0.8 0.3 0.7 -1.1 0.7 0.7 0.5 0.7 0.7 1.0 1.0 1.0 0.9 0.9 0.8 0.5 1.5 0.5 0.2 0.6 1.0 -1.1 0.2 -0.5 0.9 0.9 0.8 -0.5 1.3
Commuting to job workplace: Public transport 0.2 0.3 1.4 -0.1 0.4 -0.1 1.2 -0.2 -0.4 0.4 0.7 -0.7 1.0 1.1 0.5 0.3 -1.0 0.9 0.3 -0.2 0.5 -0.4 0.5 0.3 0.3 0.2 0.1 0.2 0.3 0.0 0.3 0.9 0.2 0.5 0.0 0.7 0.4 0.8 0.3 0.6 0.2 0.2 0.2 1.0 -0.2
Eye problems/disorders: Glaucoma 0.7 0.9 2.4 0.3 1.2 1.2 -0.8 0.8 0.6 1.2 -0.3 -0.2 0.5 0.3 0.7 1.2 -0.4 -0.0 1.3 -1.1 0.2 1.1 0.6 -0.3 1.1 1.4 1.4 1.4 1.1 1.4 1.1 1.1 1.1 -0.3 -1.4 0.1 -0.1 -1.5 -0.5 -1.1 1.4 0.8 0.0 -1.2 0.6
Medication: Blood pressure 3.5 6.7 18.7 3.0 2.6 2.5 1.6 3.3 4.1 2.5 1.6 3.0 2.8 0.6 1.9 2.4 4.3 2.0 1.7 -2.4 2.2 4.3 1.5 3.3 2.4 2.3 2.3 3.3 2.6 2.4 2.5 3.0 1.7 2.1 1.2 4.2 3.0 1.2 2.2 1.7 2.6 1.8 2.5 1.2 2.6
Pain type(s) experienced in last month: Hip pain 1.2 1.5 4.1 -0.8 -1.6 -1.1 -1.2 -0.9 -0.6 -1.6 -0.9 -0.6 -1.2 -1.7 -0.9 -1.5 -1.4 -1.6 -1.0 1.4 -1.1 -0.7 -0.8 -1.7 -1.5 -1.1 -1.2 -1.3 -1.4 -1.2 -1.5 -1.2 -1.0 -1.1 0.1 -2.0 -1.2 -1.1 -1.0 -1.1 -1.5 -0.6 -1.2 -1.1 -1.0
Supplements: Fish oil (including cod liver oil) 0.2 0.3 3.7 -0.3 0.2 0.3 -0.9 0.2 -0.1 0.2 -0.1 -1.9 0.4 -1.0 0.4 0.2 -0.1 -0.2 -0.3 -0.5 0.2 0.3 0.3 0.1 0.2 0.5 0.5 0.8 0.4 0.4 0.2 0.0 0.2 -0.2 -0.3 -0.7 -0.0 -1.2 -0.7 -1.0 0.4 0.1 -0.3 -0.9 -0.3
High cholesterol (Self-reported) 0.8 1.3 5.1 -1.1 -0.8 -0.9 -2.0 -1.0 -0.7 -0.8 -1.2 -0.3 -0.5 -1.5 -0.6 -0.6 -0.7 -1.4 -1.3 0.7 -0.8 -0.1 -0.7 -1.1 -0.8 -0.6 -0.7 -0.7 -0.7 -0.6 -1.0 -0.7 -1.2 -1.5 -1.5 -1.1 -0.7 -2.1 -1.8 -2.1 -0.8 -1.3 -1.6 -2.3 -1.4
Medication: Bendroflumethiazide 0.2 0.3 1.6 -0.3 -0.3 -0.6 0.1 -0.2 1.0 -0.6 -0.7 -0.2 -0.0 -1.1 -0.2 -0.6 1.1 -0.6 -1.3 0.2 0.0 0.7 -0.6 0.8 -0.5 -0.4 -0.6 -0.1 -0.4 -0.6 -0.6 -0.0 -0.6 -0.6 -0.3 0.3 -0.0 -0.6 -0.6 -0.6 -0.6 -0.5 -0.5 -0.9 -0.5
Medication: Paracetamol 1.9 3.0 6.4 -0.2 -2.1 -1.4 -1.7 -0.8 -0.9 -2.0 -2.0 -2.5 -0.9 -2.4 -2.3 -1.9 -1.0 -2.3 -1.6 1.6 -2.2 -1.6 -2.2 -1.9 -2.2 -1.9 -1.7 -1.6 -1.8 -1.7 -1.8 -1.9 -0.9 -1.8 0.6 -1.5 -1.9 -2.1 -1.5 -1.9 -1.7 -0.7 -1.2 -1.8 -0.8
Medication: Lisinopril 1.5 2.0 4.9 2.2 1.6 1.3 0.4 1.5 1.8 1.5 0.5 1.7 1.5 0.8 1.5 1.2 2.1 1.0 0.8 -1.7 1.0 1.9 0.6 1.4 1.5 1.2 1.3 1.8 1.5 1.2 1.4 1.5 1.2 1.1 1.0 1.8 1.3 0.6 1.4 0.9 1.5 2.2 1.6 0.6 1.3
Medication: Atorvastatin 0.3 0.3 1.7 -0.3 0.2 0.4 -0.7 0.2 0.1 0.1 0.4 0.8 0.5 0.8 0.4 0.5 -0.1 -0.1 0.1 -0.3 0.2 1.1 0.6 0.6 0.3 0.6 0.5 0.5 0.4 0.6 0.3 0.1 -1.2 -0.6 -0.4 1.3 1.0 -1.0 -0.5 -0.9 0.4 -0.6 -0.4 -0.7 -0.1
Illnesses of father: High blood pressure 0.6 0.7 3.0 0.9 1.0 0.8 -1.1 1.0 1.4 1.1 -0.7 0.7 1.6 -0.1 0.1 0.9 1.7 -0.2 0.4 -1.2 0.4 1.0 -0.2 0.6 0.7 0.8 0.8 1.4 0.9 0.8 0.8 0.9 0.9 -0.5 -0.8 0.8 0.2 -0.8 -0.2 -0.6 1.0 0.1 0.5 -0.9 0.4
Alcohol drinker status: Never 3.2 3.9 10.9 -1.2 -2.4 -1.4 -2.0 -1.4 -1.6 -2.3 -1.3 -2.6 -2.9 -2.6 -1.6 -1.9 -1.6 -2.4 -1.7 2.3 -2.0 -2.3 -1.2 -1.8 -2.0 -1.6 -1.6 -2.2 -2.2 -1.7 -2.0 -2.6 -1.3 -1.8 0.2 -3.3 -2.1 -2.1 -1.7 -2.0 -1.9 -1.1 -1.8 -2.0 -1.2
Ever smoked 0.1 0.3 1.3 -0.3 -0.1 -0.1 -0.0 -0.8 -0.0 0.1 0.4 -0.2 1.1 0.7 0.6 0.0 -1.0 -0.0 0.9 -0.3 0.2 0.4 0.6 0.8 0.5 0.3 0.1 -0.3 0.4 0.2 0.0 0.4 -0.9 -0.1 -0.8 0.7 0.9 0.7 0.2 0.4 0.0 -0.1 0.0 0.2 -0.5
Basal metabolic rate 0.3 1.7 6.4 -0.7 -0.6 -1.7 1.7 -1.1 -0.2 -0.9 -0.8 -1.6 -1.0 -1.6 -1.7 -0.5 -1.8 0.5 -1.8 1.1 -1.0 -1.4 -1.8 -1.3 -1.1 -1.7 -2.0 -1.3 -0.9 -1.9 -1.0 -0.1 0.9 0.8 1.2 -0.6 -1.7 2.5 0.6 1.8 -1.4 0.6 0.2 2.0 -0.5
Leg fat percentage (left) 0.3 1.2 3.9 -0.8 -1.1 -1.1 0.4 -0.9 -1.2 -1.4 -0.1 -1.9 -1.0 -2.0 -0.7 -0.9 -1.9 -0.2 -1.4 1.4 -0.7 -1.4 -0.4 -1.0 -0.7 -1.2 -1.2 -1.5 -1.2 -1.2 -1.1 -1.2 -0.4 0.2 1.7 -1.7 -0.9 0.9 0.1 0.6 -1.2 0.2 -0.2 0.8 -0.4
Arm fat-free mass (left) 0.4 2.1 7.9 -0.4 -0.6 -1.8 1.6 -0.9 0.1 -0.9 -1.0 -1.6 -1.2 -1.6 -2.0 -0.5 -1.6 0.6 -2.0 1.0 -1.2 -1.5 -2.4 -1.4 -1.3 -2.0 -2.2 -1.2 -0.9 -2.1 -1.0 0.1 0.9 1.1 1.8 -0.1 -1.7 2.8 0.8 2.0 -1.4 1.0 0.4 2.3 -0.4
Number of operations (self-reported) 0.2 0.3 2.8 0.2 0.6 0.1 -0.9 0.4 0.5 0.5 -0.5 0.2 -0.1 0.7 -0.3 0.5 -0.7 0.0 0.5 -0.5 -0.3 0.9 -0.5 0.3 0.2 0.1 0.1 0.9 0.4 0.3 0.4 0.5 0.1 -0.3 -0.4 1.7 0.0 -0.0 -0.0 -0.1 0.5 0.7 0.1 -0.3 0.0
Average weekly beer plus cider intake 0.5 0.7 5.6 -1.0 -1.0 -0.1 -0.0 -0.9 -0.8 -0.7 1.5 1.0 0.2 -0.2 0.6 -0.8 -1.5 -0.2 0.7 0.8 0.5 -0.8 1.7 -0.6 -0.0 0.1 0.1 -1.0 -0.5 -0.0 -0.5 -0.6 -1.0 -0.1 -0.3 -2.4 0.8 0.0 -0.3 -0.0 -0.6 -1.2 -0.6 0.1 -0.6
Irritability 0.8 1.3 4.3 -1.6 -1.3 -1.1 -0.6 -1.3 -1.0 -1.1 -0.7 -1.7 -0.5 -1.2 -1.1 -1.1 -0.9 -1.1 -0.7 1.0 -0.8 -0.8 -0.6 -1.2 -1.2 -0.7 -1.0 -1.1 -0.9 -1.0 -1.0 -0.6 -0.5 -1.4 -1.2 -1.6 -0.9 -1.5 -1.6 -1.6 -1.1 -2.1 -1.2 -1.1 -1.5
Risk taking 0.5 0.7 2.9 -1.4 -0.9 -0.9 1.0 -1.4 -0.4 -0.8 0.8 -1.2 -0.3 -0.9 -0.1 -0.5 -1.7 0.2 -0.6 0.8 -0.0 -0.2 0.4 -0.5 -0.3 -0.4 -0.6 -1.1 -0.5 -0.6 -0.6 -0.1 -1.7 -0.3 -0.3 -0.8 0.2 0.4 -0.5 0.0 -0.8 -1.6 -1.0 0.2 -1.2
Ever had prostate specific antigen (PSA) test 0.6 0.6 4.3 1.7 0.4 0.7 -0.2 1.0 0.2 0.2 0.3 0.1 1.2 0.3 0.5 0.2 0.6 0.4 0.4 -0.3 0.3 -0.2 -0.3 0.2 0.4 0.3 0.3 0.1 0.3 0.3 0.3 -0.1 0.9 1.0 2.1 0.5 0.3 0.9 1.4 1.1 0.3 2.1 1.2 1.0 1.4
Fractured/broken bones in last 5 years 0.6 0.7 5.7 -0.0 -0.3 -0.3 1.9 -0.3 0.0 -0.2 1.2 0.5 -0.5 1.0 0.5 -0.3 -0.2 1.0 0.4 0.3 0.6 -0.5 0.6 0.6 0.1 -0.2 -0.3 -0.5 -0.2 -0.3 -0.1 0.6 -0.3 1.3 1.6 -0.4 0.5 2.4 1.2 1.9 -0.3 0.9 0.4 2.0 -0.0
Age started oral contraceptive pill 0.6 0.7 2.2 0.7 0.8 1.0 0.1 1.0 0.8 0.6 1.0 0.6 1.3 1.1 1.2 0.5 1.5 0.6 0.8 -0.9 1.1 0.6 0.9 1.5 0.9 1.0 0.8 0.6 1.0 0.9 0.6 0.8 0.5 0.9 0.2 0.8 1.1 0.5 0.9 0.6 0.6 0.7 1.0 0.3 1.0
Diastolic blood pressure, automated reading 5.7 17.5 42.8 4.9 4.6 3.8 2.3 4.9 6.5 4.7 2.5 4.6 5.3 2.7 3.3 4.5 5.1 3.8 1.0 -4.7 3.9 4.2 1.8 5.1 3.8 3.6 3.5 5.1 4.6 3.7 4.3 5.6 4.5 3.7 1.2 5.6 3.8 3.3 4.2 3.7 4.3 4.3 4.7 3.2 4.4
Ever depressed for a whole week 0.2 0.3 2.8 -0.3 0.2 -0.1 1.7 -0.2 0.5 0.2 0.6 0.3 -0.3 -0.5 0.1 0.2 0.4 0.7 1.2 -0.4 0.6 0.6 0.4 0.6 0.1 -0.0 0.1 0.3 0.2 0.1 0.3 0.7 -0.3 0.5 -0.0 0.2 0.6 0.2 -0.1 0.0 0.1 -1.0 -0.1 0.6 -0.5
Unable to work because of sickness or disability 3.6 4.7 7.8 -2.8 -2.5 -2.5 -1.4 -2.3 -2.2 -2.2 -1.7 -2.0 -1.8 -2.2 -2.1 -2.6 -2.4 -2.1 -1.2 2.7 -2.2 -1.7 -1.5 -2.0 -2.1 -2.5 -2.3 -2.2 -2.7 -2.3 -2.4 -2.3 -2.8 -1.7 -0.9 -2.1 -2.2 -1.2 -2.2 -1.6 -2.4 -2.2 -2.5 -1.4 -2.4
Commuting to job workplace: Cycle 0.2 0.2 2.7 0.1 0.6 -0.1 0.2 -0.1 -0.2 0.7 -0.1 0.1 0.3 1.6 -0.0 0.8 -0.8 0.4 -0.7 -0.7 0.1 -0.2 -0.3 -0.3 0.0 0.2 0.1 0.4 0.5 0.2 0.4 0.4 0.2 -0.0 -0.2 1.1 0.1 0.4 0.1 0.2 0.4 0.1 -0.0 0.1 -0.1
Myopia 0.3 0.4 1.4 -0.2 0.7 0.6 -1.1 0.1 -0.1 0.9 -0.2 -0.6 1.1 -0.2 0.4 0.7 0.5 -0.3 0.2 -1.0 0.4 0.2 0.6 0.1 0.7 0.8 0.8 0.6 0.7 0.8 0.6 0.4 0.5 -0.5 -1.2 -0.1 0.1 -0.8 -0.5 -0.7 0.7 -0.1 0.0 -1.0 -0.1
Vascular/heart problems diagnosed by doctor 4.2 11.5 28.3 -4.0 -3.6 -3.3 -2.2 -4.2 -5.3 -3.5 -2.1 -3.8 -3.2 -2.1 -2.8 -3.4 -4.8 -2.8 -1.6 3.5 -3.4 -4.7 -2.2 -4.5 -3.1 -3.2 -3.2 -4.4 -3.5 -3.3 -3.5 -3.5 -2.8 -3.1 -1.4 -4.6 -3.8 -2.3 -3.3 -2.7 -3.6 -2.7 -3.4 -2.1 -3.5
Cholesterol lowering medication 0.9 1.3 5.0 1.2 1.3 1.6 -0.4 1.5 1.4 1.3 0.5 0.8 1.0 -0.9 1.1 1.4 1.6 0.4 1.3 -1.1 0.8 2.2 0.9 0.9 1.2 1.2 1.5 1.6 1.2 1.6 1.3 1.1 0.4 0.3 -0.5 1.6 1.3 -0.9 0.4 -0.4 1.5 0.2 0.6 -0.8 1.1
Medication: Omeprazole (e.g. Zanprol) 0.2 0.3 1.9 1.4 0.1 0.6 -0.4 0.8 0.4 -0.0 0.0 0.4 0.8 -0.3 0.4 0.2 0.1 -0.2 0.9 -0.1 0.1 0.1 0.3 0.4 0.2 0.3 0.3 0.2 0.2 0.4 0.1 -0.1 0.5 0.1 0.8 -0.4 0.3 0.2 0.8 0.4 0.2 1.4 0.7 -0.0 0.9
Pain experienced in last month 0.1 0.2 1.2 -0.6 -0.3 0.1 -0.1 -0.4 -0.1 -0.2 0.7 -0.1 -0.4 1.1 0.5 -0.4 -0.8 0.1 -0.0 0.2 0.4 -0.3 0.2 0.3 0.1 0.1 0.2 -0.5 -0.3 0.0 -0.2 -0.4 -1.1 0.1 0.1 -0.1 0.7 0.1 -0.0 0.1 -0.2 -1.0 -0.3 -0.0 -0.2
Supplements: Calcium 0.9 1.0 6.0 1.1 1.0 1.0 0.2 1.4 1.2 1.1 0.2 0.6 0.2 -0.1 0.2 1.0 2.5 0.9 0.6 -1.2 0.7 0.7 0.3 0.8 0.9 0.9 0.9 1.3 1.1 0.9 1.1 0.5 2.3 1.1 -0.1 0.6 0.4 0.8 1.0 1.0 1.1 1.1 1.4 1.0 1.3
Basal cell carcinoma (self-reported) 0.3 0.3 2.6 -0.6 0.1 -0.3 1.6 -0.8 -0.7 0.0 1.2 0.5 -0.1 0.1 0.8 0.1 -1.0 0.9 0.8 0.3 0.6 0.3 0.8 0.2 0.2 0.0 -0.0 -0.2 -0.1 -0.1 0.0 0.4 -1.0 0.1 -0.5 -0.2 0.6 0.8 0.1 0.5 -0.1 -0.5 -0.2 0.7 -0.8
Heart attack/myocardial infarction (self-reported) 4.0 5.2 11.0 2.7 2.4 2.6 0.8 2.6 3.0 2.5 2.0 3.1 2.0 2.3 2.3 2.4 2.2 2.0 1.9 -2.5 2.1 3.3 1.8 2.5 2.4 2.3 2.6 2.8 2.5 2.6 2.5 2.1 1.4 1.8 1.0 3.2 2.8 0.6 1.7 1.1 2.6 1.9 1.9 1.1 2.2
Deep venous thrombosis (DVT) (self-reported) 0.7 0.9 3.6 1.3 0.8 1.4 -0.2 1.6 1.9 0.8 0.8 0.1 1.2 0.3 0.8 0.6 0.5 0.5 1.0 -0.8 0.8 0.8 0.8 1.2 0.8 0.8 1.1 0.9 0.8 1.1 1.0 0.3 0.7 0.8 0.8 0.9 0.9 0.2 1.1 0.6 0.9 1.2 1.2 0.6 1.6
Heart disease (siblings) 0.2 0.3 2.4 0.3 -0.0 -0.1 -1.6 0.0 0.5 -0.2 -0.8 -0.2 -0.2 -1.0 -0.2 0.1 0.1 -0.6 -0.5 -0.0 -0.5 0.7 -0.8 -0.6 -0.5 -0.2 -0.0 0.1 -0.1 -0.1 -0.2 0.0 -0.4 -0.6 0.2 0.4 -0.1 -1.2 -0.5 -1.0 0.0 -0.0 -0.3 -1.1 -0.1
Alcohol drinker status: Previous 0.9 1.0 5.1 0.9 0.9 0.8 1.8 0.8 0.4 0.9 0.9 2.3 0.7 1.6 0.9 0.8 -0.6 0.9 1.3 -1.0 0.8 1.1 1.0 0.7 1.0 0.8 0.7 0.7 1.0 0.8 0.8 1.0 0.7 1.1 1.0 0.7 0.9 1.3 1.1 1.2 0.7 0.8 1.0 1.2 0.8
Pack years of smoking 1.5 2.2 8.6 -1.1 -1.2 -0.9 -2.5 -1.3 -1.3 -1.3 -1.3 -1.1 -1.4 -0.7 -0.4 -1.1 -1.3 -1.9 -1.2 1.1 -1.2 -1.0 -0.7 -1.0 -1.0 -0.7 -0.7 -1.3 -1.3 -0.7 -1.3 -2.1 -1.4 -2.0 -1.8 -1.9 -0.9 -2.9 -2.1 -2.7 -1.0 -1.1 -1.9 -2.6 -1.4
Impedance of whole body 0.2 0.9 3.7 -1.0 -0.4 0.2 -1.6 -0.7 -1.0 -0.2 0.2 0.8 0.2 1.5 1.0 -0.6 -0.4 -0.9 1.0 0.3 0.3 0.0 1.0 0.7 0.1 0.6 0.6 -0.3 -0.4 0.4 -0.3 -0.6 -1.9 -1.2 -1.5 -0.6 0.7 -1.9 -1.2 -1.7 -0.0 -1.4 -1.1 -1.8 -1.0
Leg fat mass (left) 0.5 1.8 5.6 -1.2 -1.3 -1.5 0.8 -1.4 -1.3 -1.6 -0.3 -2.2 -1.2 -2.2 -1.1 -1.1 -2.4 -0.2 -1.8 1.7 -0.8 -1.7 -0.7 -1.2 -1.0 -1.6 -1.7 -1.9 -1.4 -1.6 -1.4 -1.3 -0.3 0.2 1.5 -2.0 -1.2 1.3 0.0 0.8 -1.6 -0.1 -0.4 1.0 -0.8
Arm predicted mass (left) 0.4 1.9 7.7 -0.4 -0.5 -1.7 1.7 -0.9 0.2 -0.7 -1.0 -1.6 -1.0 -1.4 -2.0 -0.3 -1.6 0.7 -1.9 0.8 -1.2 -1.3 -2.2 -1.4 -1.1 -1.8 -2.1 -1.0 -0.7 -1.9 -0.8 0.1 1.2 1.1 1.5 0.0 -1.8 2.8 0.7 2.0 -1.3 0.9 0.4 2.3 -0.4