[Hub]/) : Traits : High blood pressure :

chr15:90,712,555-92,187,978

Best TWAS P=1.13e-38 · Best GWAS P=8.67e-29 conditioned to 0.591

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FURIN 0.12 0.14 lasso 2 0.13 1.2e-15 -7.3 7.3 3.7e-13 0.82 0.99 0.01 TRUE
2 GTEx Adipose Visceral Omentum FES 0.21 0.09 lasso 5 0.05 1.3e-03 11.1 -10.9 1.5e-27 -0.70 0.01 0.98 FALSE
3 GTEx Artery Tibial FES 0.16 0.04 lasso 5 0.05 4.8e-05 10.1 -11.3 1.0e-29 -0.73 0.02 0.98 FALSE
4 GTEx Breast Mammary Tissue (Male) RCCD1 0.33 -0.01 enet 28 0.07 1.3e-02 11.1 5.5 3.9e-08 0.45 0.03 0.50 FALSE
5 GTEx Cells Transformed fibroblasts FES 0.28 0.17 enet 21 0.20 2.8e-15 11.1 -11.9 9.6e-33 -0.90 0.01 0.99 FALSE
6 GTEx Lung FES 0.24 0.07 lasso 6 0.05 5.1e-05 10.1 -11.8 5.3e-32 -0.79 0.01 0.98 FALSE
7 GTEx Skin Sun Exposed Lower leg FES 0.09 0.04 lasso 5 0.04 1.4e-04 11.1 -9.6 8.9e-22 -0.66 0.01 0.96 FALSE
8 GTEx Thyroid FES 0.33 0.19 lasso 6 0.18 4.3e-14 10.6 -10.6 2.3e-26 -0.70 0.03 0.97 TRUE
9 METSIM Adipose FES 0.08 0.06 lasso 3 0.05 6.8e-08 10.1 -10.4 3.1e-25 -0.63 0.26 0.74 FALSE
10 YFS Blood FES 0.31 0.11 enet 77 0.22 1.2e-68 11.1 -10.4 1.9e-25 -0.68 0.00 1.00 FALSE
11 YFS Blood FURIN 0.11 0.03 enet 37 0.06 8.3e-19 -7.3 -7.8 6.1e-15 -0.67 0.13 0.87 FALSE
12 The Cancer Genome Atlas Bladder Urothelial Carcinoma FES 0.06 0.05 blup 46 0.06 1.9e-05 11.0 -10.2 1.7e-24 -0.83 0.00 0.99 FALSE
13 The Cancer Genome Atlas Breast Invasive Carcinoma FES 0.06 0.05 blup 46 0.07 7.4e-14 11.1 -13.0 1.1e-38 -0.89 0.00 1.00 TRUE
14 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma FES 0.06 0.02 blup 46 0.02 2.4e-02 11.1 -11.0 4.7e-28 -0.77 0.00 0.87 FALSE
15 The Cancer Genome Atlas Colon Adenocarcinoma FES 0.08 0.07 blup 46 0.06 3.4e-04 10.6 -11.3 2.2e-29 -0.91 0.01 0.96 FALSE
16 The Cancer Genome Atlas Glioblastoma Multiforme FES 0.12 0.06 enet 6 0.06 5.7e-03 11.0 -10.5 5.3e-26 -0.94 0.01 0.90 FALSE
17 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma FES 0.06 0.03 blup 46 0.05 5.6e-06 11.0 -10.5 5.7e-26 -0.81 0.01 0.99 FALSE
18 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma FES 0.10 0.07 enet 5 0.05 2.8e-06 11.1 -10.6 1.9e-26 -0.99 0.00 1.00 FALSE
19 The Cancer Genome Atlas Lung Adenocarcinoma FES 0.05 0.04 lasso 2 0.04 2.2e-05 11.1 -11.9 6.9e-33 -0.90 0.01 0.99 FALSE
20 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FES 0.08 0.07 enet 7 0.08 4.2e-09 11.1 -11.6 3.1e-31 -0.82 0.00 1.00 FALSE
21 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma FES 0.13 0.16 lasso 2 0.14 6.1e-10 11.1 -11.0 3.5e-28 -0.71 0.01 0.99 FALSE
22 The Cancer Genome Atlas Prostate Adenocarcinoma FES 0.12 0.09 lasso 5 0.08 4.1e-09 11.1 -12.2 2.7e-34 -0.80 0.00 1.00 FALSE
23 The Cancer Genome Atlas Stomach Adenocarcinoma FES 0.04 0.01 blup 46 0.02 1.7e-02 11.0 -11.0 6.1e-28 -0.78 0.01 0.61 FALSE
24 The Cancer Genome Atlas Testicular Germ Cell Tumors FES 0.32 0.26 lasso 2 0.25 2.0e-09 11.1 -11.2 4.0e-29 -0.72 0.00 1.00 FALSE
25 The Cancer Genome Atlas Thyroid Carcinoma FES 0.30 0.30 lasso 7 0.32 1.3e-31 11.1 -12.2 2.7e-34 -0.84 0.00 1.00 FALSE