[Hub]/) : Traits : High blood pressure : ← →

chr16:3,025,993-5,441,125

Best TWAS P=8.65e-11 · Best GWAS P=1.84e-09 conditioned to 1.65e-06

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum AC006111.1 0.18 0.12 enet 12 0.10 1.1e-05 3.2 5.2 1.6e-07 0.02 0.66 0.03 FALSE
2 GTEx Brain Cortex AC006111.1 0.32 0.02 enet 16 0.00 3.2e-01 -4.0 5.6 1.8e-08 -0.04 0.04 0.10 TRUE
3 GTEx Heart Atrial Appendage MGRN1 0.33 0.30 enet 13 0.32 7.1e-15 -3.7 5.5 3.1e-08 -0.19 0.96 0.02 FALSE
4 GTEx Heart Left Ventricle MGRN1 0.32 0.10 enet 18 0.33 3.6e-18 3.8 6.5 8.6e-11 -0.20 0.94 0.03 TRUE
5 GTEx Muscle Skeletal MGRN1 0.16 0.06 lasso 7 0.15 1.1e-14 4.0 6.2 5.2e-10 -0.18 0.94 0.03 FALSE
6 GTEx Skin Not Sun Exposed Suprapubic AC006111.1 0.19 0.12 enet 13 0.18 2.1e-10 -2.5 5.6 2.6e-08 0.02 0.11 0.88 FALSE
7 METSIM Adipose NUDT16L1 0.06 0.03 bslmm 392 0.04 2.2e-06 -3.4 -5.7 1.1e-08 0.33 0.85 0.13 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma NAT15 0.05 0.04 blup 56 0.03 1.7e-07 4.6 -5.8 7.6e-09 -0.02 0.30 0.70 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma NAT15 0.06 0.04 blup 56 0.04 4.1e-05 5.6 -5.7 1.0e-08 -0.01 0.02 0.95 FALSE
10 The Cancer Genome Atlas Lung Squamous Cell Carcinoma NAT15 0.04 0.01 blup 56 0.04 4.2e-05 5.2 -5.6 2.3e-08 -0.05 0.02 0.92 FALSE
11 The Cancer Genome Atlas Soft Tissue Sarcoma NAT15 0.20 0.08 enet 14 0.17 1.8e-10 5.6 -5.2 1.8e-07 -0.01 0.05 0.94 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma NAT15 0.10 0.05 lasso 6 0.07 6.1e-07 5.9 -5.8 5.9e-09 -0.04 0.01 0.99 TRUE