[Hub]/) : Traits : High blood pressure : ← →

chr16:3,025,993-5,441,125

Best TWAS P=8.65e-11 · Best GWAS P=1.84e-09 conditioned to 1.65e-06

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Heart Left Ventricle	MGRN1	0.32	0.10	enet	18	0.33	3.6e-18	3.8	6.5	8.6e-11	-0.20	0.94	0.03	TRUE
12	The Cancer Genome Atlas	Thyroid Carcinoma	NAT15	0.10	0.05	lasso	6	0.07	6.1e-07	5.9	-5.8	5.9e-09	-0.04	0.01	0.99	TRUE
2	GTEx	Brain Cortex	AC006111.1	0.32	0.02	enet	16	0.00	3.2e-01	-4.0	5.6	1.8e-08	-0.04	0.04	0.10	TRUE
5	GTEx	Muscle Skeletal	MGRN1	0.16	0.06	lasso	7	0.15	1.1e-14	4.0	6.2	5.2e-10	-0.18	0.94	0.03	FALSE
8	The Cancer Genome Atlas	Breast Invasive Carcinoma	NAT15	0.05	0.04	blup	56	0.03	1.7e-07	4.6	-5.8	7.6e-09	-0.02	0.30	0.70	FALSE
9	The Cancer Genome Atlas	Lung Adenocarcinoma	NAT15	0.06	0.04	blup	56	0.04	4.1e-05	5.6	-5.7	1.0e-08	-0.01	0.02	0.95	FALSE
7	METSIM	Adipose	NUDT16L1	0.06	0.03	bslmm	392	0.04	2.2e-06	-3.4	-5.7	1.1e-08	0.33	0.85	0.13	FALSE
10	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	NAT15	0.04	0.01	blup	56	0.04	4.2e-05	5.2	-5.6	2.3e-08	-0.05	0.02	0.92	FALSE
6	GTEx	Skin Not Sun Exposed Suprapubic	AC006111.1	0.19	0.12	enet	13	0.18	2.1e-10	-2.5	5.6	2.6e-08	0.02	0.11	0.88	FALSE
3	GTEx	Heart Atrial Appendage	MGRN1	0.33	0.30	enet	13	0.32	7.1e-15	-3.7	5.5	3.1e-08	-0.19	0.96	0.02	FALSE
1	GTEx	Adipose Visceral Omentum	AC006111.1	0.18	0.12	enet	12	0.10	1.1e-05	3.2	5.2	1.6e-07	0.02	0.66	0.03	FALSE
11	The Cancer Genome Atlas	Soft Tissue Sarcoma	NAT15	0.20	0.08	enet	14	0.17	1.8e-10	5.6	-5.2	1.8e-07	-0.01	0.05	0.94	FALSE