TWAS
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About
Usage
Models
Genes
Traits
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Traits
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High blood pressure
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chr17:3,208,350-4,766,937
Best TWAS P=3.14e-09 · Best GWAS P=1.22e-08 conditioned to 0.346
3.2M
3.4M
3.6M
3.8M
4M
4.2M
4.4M
4.6M
4.8M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Artery Coronary
RP11-810M2.2
0.30
0.02
lasso
4
0.02
0.085
5.5
5.9
3.1e-09
0.89
0.02
0.80
TRUE
2
GTEx
Muscle Skeletal
ZZEF1
0.11
0.01
lasso
3
0.01
0.019
5.5
5.5
4.6e-08
0.97
0.01
0.97
FALSE