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chr17:73,175,294-74,629,867

Best TWAS P=1.17e-08 · Best GWAS P=1.91e-08 conditioned to 0.197

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	FBF1	0.36	0.29	lasso	2	0.29	5.4e-24	-5.6	-5.7	1.6e-08	0.89	0.00	1.00	FALSE
2	GTEx	Adipose Visceral Omentum	FBF1	0.29	0.23	lasso	1	0.22	1.4e-11	-5.6	-5.6	2.0e-08	0.88	0.00	1.00	FALSE
3	GTEx	Artery Aorta	FBF1	0.32	0.27	lasso	2	0.26	2.2e-14	-5.6	-5.6	2.6e-08	0.89	0.00	1.00	FALSE
4	GTEx	Artery Coronary	FBF1	0.41	0.18	lasso	8	0.14	2.2e-05	-5.6	-5.1	2.8e-07	0.86	0.00	1.00	FALSE
5	GTEx	Artery Tibial	FBF1	0.36	0.33	enet	12	0.33	3.7e-26	-5.6	-5.5	4.9e-08	0.92	0.00	1.00	FALSE
6	GTEx	Brain Caudate basal ganglia	FBF1	0.35	0.20	enet	27	0.19	3.3e-06	-5.6	-5.2	1.8e-07	0.83	0.01	0.99	FALSE
7	GTEx	Breast Mammary Tissue	FBF1	0.15	0.20	lasso	3	0.19	6.9e-10	-5.6	-5.6	1.8e-08	0.89	0.00	1.00	FALSE
8	GTEx	Colon Transverse	FBF1	0.28	0.21	lasso	3	0.19	2.8e-09	-5.6	-5.5	3.0e-08	0.86	0.00	1.00	FALSE
9	GTEx	Esophagus Muscularis	FBF1	0.34	0.33	lasso	3	0.32	5.5e-20	-5.6	-5.7	1.2e-08	0.88	0.00	1.00	TRUE
10	GTEx	Lung	FBF1	0.20	0.18	lasso	1	0.17	2.6e-13	-5.6	-5.6	2.0e-08	0.88	0.00	1.00	FALSE
11	GTEx	Nerve Tibial	FBF1	0.54	0.46	enet	37	0.45	2.9e-35	-5.6	-5.2	2.3e-07	0.86	0.00	1.00	FALSE
12	GTEx	Pituitary	FBF1	0.34	0.37	lasso	4	0.39	7.6e-11	-5.6	-5.4	5.3e-08	0.89	0.00	1.00	FALSE
13	GTEx	Prostate	FBF1	0.26	0.24	lasso	1	0.20	1.2e-05	-5.6	-5.6	2.0e-08	0.88	0.00	1.00	FALSE
14	GTEx	Skin Sun Exposed Lower leg	TRIM47	0.09	0.03	lasso	3	0.03	1.5e-03	-5.3	5.4	5.8e-08	-0.89	0.01	0.99	FALSE
15	GTEx	Skin Sun Exposed Lower leg	FBF1	0.22	0.23	lasso	1	0.21	3.0e-17	-5.6	-5.6	2.0e-08	0.88	0.00	1.00	FALSE
16	GTEx	Stomach	FBF1	0.28	0.17	enet	12	0.17	1.5e-08	-5.6	-5.6	1.9e-08	0.94	0.00	1.00	FALSE
17	GTEx	Testis	FBF1	0.37	0.38	lasso	2	0.38	8.4e-18	-5.6	-5.6	1.9e-08	0.88	0.00	1.00	FALSE
18	GTEx	Thyroid	TRIM65	0.19	0.11	lasso	2	0.09	3.5e-07	-5.6	-5.3	1.3e-07	0.85	0.00	1.00	FALSE
19	GTEx	Thyroid	FBF1	0.24	0.23	lasso	2	0.23	8.0e-18	-5.6	-5.3	1.4e-07	0.87	0.00	1.00	FALSE