[Hub]/) : Traits : High blood pressure :

chr17:60,858,059-62,279,811

Best TWAS P=1.32e-15 · Best GWAS P=1.32e-15 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ACE 0.08 0.05 lasso 4 0.04 1.0e-05 4.7 5.9 3.2e-09 0.82 0.01 0.99 FALSE
2 GTEx Colon Transverse ACE 0.31 0.28 lasso 2 0.28 1.8e-13 8.0 -7.8 9.5e-15 -0.98 0.00 1.00 FALSE
3 The Cancer Genome Atlas Breast Invasive Carcinoma ACE 0.02 0.01 enet 3 0.01 1.3e-03 7.1 7.7 1.1e-14 0.93 0.00 0.98 FALSE
4 The Cancer Genome Atlas Colon Adenocarcinoma ACE 0.34 0.22 lasso 5 0.22 6.5e-13 7.1 -7.8 5.1e-15 -0.94 0.00 1.00 FALSE
5 The Cancer Genome Atlas Colon Adenocarcinoma CYB561 0.17 0.01 enet 6 0.08 2.0e-05 7.2 -5.5 4.8e-08 -0.58 0.01 0.44 FALSE
6 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma ACE 0.16 0.08 lasso 2 0.07 5.8e-05 7.1 -7.9 3.8e-15 -0.96 0.00 1.00 FALSE
7 The Cancer Genome Atlas Pancreatic Adenocarcinoma ACE 0.13 0.14 lasso 1 0.10 6.6e-05 8.0 -8.0 1.3e-15 -1.00 0.00 1.00 TRUE
8 The Cancer Genome Atlas Rectum Adenocarcinoma ACE 0.16 0.14 lasso 6 0.13 5.1e-04 8.0 -7.6 3.3e-14 -0.95 0.00 0.88 FALSE
9 The Cancer Genome Atlas Stomach Adenocarcinoma ACE 0.06 0.03 blup 53 0.02 9.3e-03 7.2 -5.4 7.6e-08 -0.72 0.02 0.95 FALSE