Best TWAS P=7.94e-12 · Best GWAS P=3.82e-11 conditioned to 0.56
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | AC008781.7 | 0.17 | 0.00 | enet | 45 | 0.04 | 4.7e-04 | 3.1 | 5.8 | 8.9e-09 | 0.01 | 0.09 | 0.04 | TRUE |
| 2 | GTEx | Muscle Skeletal | NDFIP1 | 0.20 | 0.10 | lasso | 9 | 0.12 | 3.8e-12 | 6.6 | -6.8 | 7.9e-12 | -0.93 | 0.01 | 0.99 | TRUE |
| 3 | METSIM | Adipose | NDFIP1 | 0.23 | 0.15 | lasso | 8 | 0.16 | 7.1e-23 | 5.2 | 5.3 | 1.0e-07 | 0.73 | 0.98 | 0.02 | FALSE |
| 4 | NTR | Blood | NDFIP1 | 0.03 | 0.00 | blup | 610 | 0.01 | 2.9e-03 | 5.5 | 5.4 | 5.7e-08 | 0.63 | 0.03 | 0.96 | FALSE |