Best TWAS P=1.09e-08 · Best GWAS P=3.12e-09 conditioned to 0.111
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | ME2 | 0.08 | 0.06 | lasso | 3 | 0.05 | 6.1e-05 | -5.7 | 5.2 | 2.7e-07 | -0.91 | 0.07 | 0.92 | FALSE |
| 2 | GTEx | Spleen | SMAD4 | 0.33 | 0.10 | enet | 1 | 0.08 | 5.6e-03 | -5.6 | -5.6 | 2.0e-08 | 0.98 | 0.04 | 0.60 | FALSE |
| 3 | YFS | Blood | SMAD4 | 0.03 | 0.03 | lasso | 12 | 0.03 | 1.2e-10 | -5.9 | -5.7 | 1.1e-08 | 0.94 | 0.02 | 0.98 | TRUE |