Best TWAS P=3.59e-09 · Best GWAS P=1.65e-09 conditioned to 0.134
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | PPOX | 0.14 | 0.14 | lasso | 4 | 0.13 | 6.0e-10 | -5.8 | -5.9 | 3.6e-09 | 0.93 | 0 | 1 | TRUE |
| 6 | YFS | Blood | FCER1G | 0.46 | 0.42 | lasso | 8 | 0.45 | 4.2e-166 | -6.0 | -5.8 | 6.3e-09 | 0.97 | 0 | 1 | FALSE |
| 3 | GTEx | Cells Transformed fibroblasts | ADAMTS4 | 0.35 | 0.22 | lasso | 7 | 0.26 | 1.5e-19 | -5.8 | -5.7 | 9.8e-09 | 0.92 | 0 | 1 | FALSE |
| 4 | METSIM | Adipose | FCER1G | 0.15 | 0.11 | enet | 15 | 0.12 | 6.3e-17 | -6.0 | -5.6 | 1.7e-08 | 0.93 | 0 | 1 | FALSE |
| 5 | NTR | Blood | FCER1G | 0.17 | 0.14 | lasso | 6 | 0.16 | 3.4e-49 | -6.0 | -5.4 | 5.7e-08 | 0.96 | 0 | 1 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | B4GALT3 | 0.31 | 0.28 | enet | 16 | 0.30 | 2.0e-22 | -5.8 | -5.4 | 5.8e-08 | 0.90 | 0 | 1 | FALSE |