[Hub]/) : Traits : Blood clot in the leg (DVT) : ← →

chr9:134,907,263-137,552,398

Best TWAS P=1.17e-69 · Best GWAS P=3.68e-65 conditioned to 0.00542

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Tibial	CACFD1	0.10	0.03	lasso	4	0.03	1.7e-03	-2.23	7.8	7.1e-15	0.40	0.13	0.35	FALSE
2	GTEx	Brain Cerebellar Hemisphere	AK8	0.43	0.12	enet	24	0.08	3.8e-03	-0.78	5.2	1.6e-07	0.20	0.12	0.10	TRUE
3	GTEx	Breast Mammary Tissue	VAV2	0.38	0.11	lasso	10	0.18	1.2e-09	-0.82	7.0	2.7e-12	0.38	0.45	0.50	FALSE
4	GTEx	Breast Mammary Tissue	AL590710.1	0.31	0.11	lasso	7	0.12	1.3e-06	-1.45	7.7	1.0e-14	0.36	0.11	0.81	FALSE
5	GTEx	Spleen	SARDH	0.40	-0.01	enet	49	0.10	1.3e-03	1.54	5.8	5.3e-09	0.17	0.07	0.08	TRUE
6	GTEx	Testis	CACFD1	0.26	0.05	enet	25	0.10	5.3e-05	11.35	6.4	2.0e-10	0.23	0.30	0.14	FALSE
7	GTEx	Uterus	SURF1	0.40	0.05	enet	18	0.08	9.2e-03	8.80	-7.0	2.4e-12	-0.21	0.07	0.11	FALSE
8	METSIM	Adipose	C9orf96	0.07	0.01	blup	605	0.03	7.8e-05	-0.48	7.9	2.8e-15	0.38	0.09	0.29	FALSE
9	METSIM	Adipose	VAV2	0.09	0.03	bslmm	690	0.03	2.9e-05	-3.65	-5.1	2.7e-07	-0.07	0.18	0.03	TRUE
10	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ABO	0.08	0.01	blup	43	0.07	7.9e-07	16.29	12.6	2.4e-36	0.77	0.01	0.98	FALSE
11	The Cancer Genome Atlas	Breast Invasive Carcinoma	ABO	0.07	0.08	lasso	3	0.08	5.0e-16	16.29	16.3	1.1e-59	0.94	0.39	0.61	FALSE
12	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	ABO	0.11	0.05	blup	43	0.12	1.2e-06	-6.62	13.3	2.7e-40	0.77	0.02	0.97	FALSE
13	The Cancer Genome Atlas	Colon Adenocarcinoma	ABO	0.27	0.31	blup	43	0.33	2.1e-19	16.34	16.5	5.2e-61	0.87	0.01	0.99	FALSE
14	The Cancer Genome Atlas	Esophageal Carcinoma	ABO	0.27	0.13	lasso	2	0.11	1.8e-04	16.34	16.3	1.2e-59	0.93	0.02	0.96	FALSE
15	The Cancer Genome Atlas	Glioblastoma Multiforme	ABO	0.18	0.01	blup	42	0.07	3.0e-03	16.34	15.0	1.5e-50	0.84	0.00	0.74	FALSE
16	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ABO	0.11	0.08	blup	43	0.12	2.5e-13	16.34	15.0	1.3e-50	0.78	0.01	0.99	FALSE
17	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ABO	0.20	0.19	blup	43	0.33	3.0e-38	-6.59	12.2	3.7e-34	0.79	0.58	0.42	FALSE
18	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C9orf7	0.09	0.00	blup	21	0.03	2.2e-04	-2.39	6.1	8.2e-10	0.28	0.01	0.03	FALSE
19	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	REXO4	0.04	0.01	lasso	4	0.02	1.4e-03	-0.44	-6.5	6.9e-11	-0.30	0.01	0.84	FALSE
20	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	ABO	0.31	0.38	lasso	5	0.42	3.1e-26	16.98	16.3	8.4e-60	0.97	0.01	0.99	FALSE
21	The Cancer Genome Atlas	Brain Lower Grade Glioma	ABO	0.26	0.23	enet	10	0.26	6.0e-29	16.29	16.8	3.2e-63	0.88	0.95	0.05	FALSE
22	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	ABO	0.23	0.23	lasso	2	0.24	2.2e-11	16.98	17.0	6.7e-65	0.99	0.00	1.00	FALSE
23	The Cancer Genome Atlas	Lung Adenocarcinoma	ABO	0.21	0.25	lasso	5	0.25	2.1e-29	16.29	16.7	8.0e-63	0.97	0.02	0.98	FALSE
24	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ABO	0.08	0.06	blup	43	0.09	1.7e-10	16.29	13.9	9.0e-44	0.89	0.00	1.00	FALSE
25	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	ABO	0.28	0.22	lasso	8	0.22	1.2e-14	16.29	16.5	2.1e-61	0.94	0.01	0.99	FALSE
26	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ABO	0.23	0.21	lasso	5	0.20	6.7e-09	16.98	16.4	2.1e-60	0.95	0.00	1.00	FALSE
27	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	ABO	0.23	0.23	lasso	3	0.23	2.0e-09	16.34	16.2	1.1e-58	0.95	0.01	0.99	FALSE
28	The Cancer Genome Atlas	Prostate Adenocarcinoma	ABO	0.18	0.15	blup	43	0.21	3.4e-21	16.98	12.8	1.5e-37	0.84	0.00	1.00	FALSE
29	The Cancer Genome Atlas	Rectum Adenocarcinoma	ABO	0.48	0.23	enet	10	0.27	4.7e-07	17.05	17.6	1.2e-69	0.89	0.00	0.98	TRUE
30	The Cancer Genome Atlas	Soft Tissue Sarcoma	ABO	0.32	0.18	enet	10	0.20	2.3e-12	16.29	14.7	5.3e-49	0.85	0.01	0.99	FALSE
31	The Cancer Genome Atlas	Skin Cutaneous Melanoma	ABO	0.38	0.11	blup	43	0.15	9.6e-05	7.80	13.5	1.2e-41	0.76	0.02	0.86	FALSE
32	The Cancer Genome Atlas	Stomach Adenocarcinoma	ABO	0.20	0.10	blup	42	0.18	5.8e-13	16.29	15.8	2.4e-56	0.83	0.01	0.99	FALSE
33	The Cancer Genome Atlas	Testicular Germ Cell Tumors	ABO	0.41	0.17	enet	12	0.25	3.0e-09	-9.91	13.4	9.9e-41	0.87	0.10	0.89	FALSE
34	The Cancer Genome Atlas	Thyroid Carcinoma	ABO	0.44	0.57	enet	18	0.60	1.9e-73	16.29	16.3	7.8e-60	0.97	0.00	1.00	FALSE
35	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	ABO	0.23	0.07	blup	44	0.12	4.3e-04	16.98	10.1	6.0e-24	0.64	0.00	0.77	FALSE