[Hub]/) : Traits : Blood clot in the leg (DVT) : ←

chr20:32,898,339-34,562,581

Best TWAS P=1.43e-08 · Best GWAS P=1.42e-08 conditioned to 0.0242

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts PROCR 0.14 0.13 lasso 2 0.11 1.9e-08 5.6 -5.6 2.0e-08 -1.00 0.00 1.00 FALSE
2 GTEx Lung TRPC4AP 0.07 0.00 lasso 6 0.00 6.6e-01 4.6 -5.5 4.4e-08 -0.91 0.03 0.62 FALSE
3 GTEx Whole Blood TRPC4AP 0.10 0.03 lasso 4 0.02 7.9e-03 5.7 -5.5 3.1e-08 -0.98 0.01 0.98 FALSE
4 METSIM Adipose EIF6 0.07 0.02 bslmm 343 0.04 2.7e-07 5.5 5.7 1.4e-08 0.73 0.02 0.98 TRUE
5 METSIM Adipose PROCR 0.04 0.00 bslmm 351 0.01 2.4e-02 4.4 -5.6 2.3e-08 -0.71 0.07 0.73 FALSE
6 ROSMAP Brain Pre-frontal Cortex TRPC4AP 0.05 0.03 lasso 4 0.03 8.7e-05 5.2 -5.2 2.3e-07 -0.98 0.03 0.95 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma PROCR 0.05 0.02 blup 44 0.05 1.3e-09 5.7 -5.5 3.3e-08 -0.90 0.00 1.00 FALSE
8 The Cancer Genome Atlas Colon Adenocarcinoma PROCR 0.09 0.07 lasso 2 0.06 2.0e-04 5.1 -5.2 1.9e-07 -0.98 0.01 0.96 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma PROCR 0.10 0.11 lasso 4 0.12 5.5e-13 5.2 -5.3 1.4e-07 -0.97 0.01 0.99 FALSE
10 The Cancer Genome Atlas Prostate Adenocarcinoma PROCR 0.04 0.05 lasso 4 0.03 3.6e-04 5.7 -5.6 2.4e-08 -0.99 0.00 0.99 FALSE