Best TWAS P=2.43e-08 · Best GWAS P=1.04e-09 conditioned to 0.00662
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NTR | Blood | ZNF76 | 0.01 | 0.00 | blup | 424 | 0.00 | 3.8e-02 | 6.1 | -5.5 | 3.5e-08 | -0.80 | 0.01 | 0.97 | FALSE |
2 | ROSMAP | Brain Pre-frontal Cortex | ZNF76 | 0.04 | 0.00 | blup | 424 | 0.02 | 2.1e-03 | 5.4 | -5.6 | 2.4e-08 | -0.81 | 0.06 | 0.88 | TRUE |
3 | YFS | Blood | ZNF76 | 0.05 | 0.08 | lasso | 4 | 0.07 | 6.7e-23 | 5.4 | -5.4 | 8.4e-08 | -0.87 | 0.17 | 0.83 | FALSE |
4 | The Cancer Genome Atlas | Thyroid Carcinoma | SCUBE3 | 0.03 | 0.01 | blup | 62 | 0.03 | 8.9e-04 | 5.1 | -5.3 | 1.5e-07 | -0.82 | 0.03 | 0.81 | FALSE |