Best TWAS P=1.36e-26 · Best GWAS P=3.39e-45 conditioned to 1.38e-21
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Visceral Omentum | LRRC32 | 0.21 | 0.00 | enet | 15 | 0.01 | 0.1490 | 11.9 | 10.7 | 1.4e-26 | 0.62 | 0.01 | 0.91 | TRUE |
2 | GTEx | Prostate | CAPN5 | 0.27 | 0.04 | lasso | 3 | 0.10 | 0.0021 | -4.9 | -5.3 | 1.0e-07 | -0.12 | 0.07 | 0.08 | FALSE |
3 | YFS | Blood | LRRC32 | 0.02 | 0.00 | bslmm | 481 | 0.00 | 0.0906 | 3.8 | -5.2 | 2.2e-07 | -0.55 | 0.17 | 0.41 | FALSE |