Best TWAS P=5.33e-09 · Best GWAS P=3.05e-10 conditioned to 5.87e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | AP001266.1 | 0.11 | 0.02 | enet | 9 | 0.09 | 2.8e-07 | 4.3 | 5.6 | 2.1e-08 | -0.41 | 0.54 | 0.29 | FALSE |
| 2 | GTEx | Artery Tibial | AP5B1 | 0.11 | 0.02 | enet | 16 | 0.07 | 1.8e-06 | 2.5 | 5.6 | 2.6e-08 | -0.41 | 0.45 | 0.40 | FALSE |
| 3 | GTEx | Cells Transformed fibroblasts | CTD-3074O7.5 | 0.41 | 0.03 | enet | 47 | 0.04 | 6.7e-04 | 3.7 | 5.1 | 2.9e-07 | -0.05 | 0.03 | 0.28 | TRUE |
| 4 | YFS | Blood | EFEMP2 | 0.12 | 0.07 | bslmm | 348 | 0.13 | 4.3e-41 | -3.3 | -5.8 | 5.3e-09 | 0.40 | 0.94 | 0.06 | TRUE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | DKFZp761E198 | 0.09 | 0.06 | lasso | 3 | 0.07 | 2.3e-08 | 4.3 | 5.3 | 1.4e-07 | -0.59 | 0.61 | 0.37 | FALSE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | DKFZp761E198 | 0.06 | 0.05 | blup | 39 | 0.05 | 3.0e-05 | 4.3 | 5.6 | 1.9e-08 | -0.56 | 0.18 | 0.58 | FALSE |