Hub : Genes

CAPN5

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0820 0.0270 2.8e-05 0.051 0.037 0.029 0.036 0.035 7.0e-07 2.6e-05 0.00015 0.00003 4.2e-05
2 GTEx Nerve Tibial 0.1340 0.0411 8.7e-06 0.056 NA 0.041 NA 0.044 8.4e-05 NA 0.00069 NA 4.3e-04
3 GTEx Prostate 0.2650 0.1070 5.9e-03 0.039 NA 0.051 NA 0.096 3.8e-02 NA 0.02100 NA 2.1e-03
4 GTEx Skin Not Sun Exposed Suprapubic 0.2670 0.0760 7.7e-04 0.007 NA -0.003 NA 0.000 1.2e-01 NA 0.48000 NA 3.2e-01
5 GTEx Spleen 0.3180 0.1060 4.7e-04 0.174 NA 0.149 NA 0.265 3.2e-05 NA 0.00012 NA 1.7e-07
6 YFS Blood 0.0289 0.0112 3.3e-04 0.006 0.007 0.010 0.008 0.007 2.6e-03 1.8e-03 0.00028 0.00110 1.6e-03
7 TCGA Breast Invasive Carcinoma 0.0175 0.0105 9.8e-03 0.010 0.009 0.011 NA 0.007 3.6e-03 5.3e-03 0.00180 NA 1.1e-02
8 TCGA Pheochromocytoma and Paraganglioma 0.1050 0.0530 1.3e-03 0.090 0.060 0.070 NA 0.065 2.0e-04 2.1e-03 0.00093 NA 1.4e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 1.2 2.0 5.3 0.3 1.5 -0.0 0.8 0.8 -1.7 -2.0 -2.3
Bipolar Disorder or Schizophrenia 0.8 2.0 4.4 1.2 2.1 -0.3 0.5 1.7 -1.6 -1.7 -1.2
Depressed Affect (Nagel 2018) 0.8 1.8 5.6 -1.5 -0.5 -2.1 -0.4 -1.1 2.4 0.5 0.0
Depression (Nagel 2018) 0.9 1.4 3.2 -0.8 -1.8 -0.7 1.1 -1.5 1.8 -0.1 0.0
Intelligence (Savage-Jansen 2018) 1.3 4.0 9.9 -1.3 -2.7 1.9 -1.5 -2.6 3.1 -0.3 0.0
Neuroticism (Nagel 2018) 0.9 2.0 5.7 -1.4 -1.6 -1.8 -0.1 -1.5 2.4 0.4 0.0
Schizophrenia (2018) 0.5 0.9 2.6 1.2 1.6 -0.4 -0.0 1.5 -0.7 -0.5 0.4
Schizophrenia vs Biploar Disorder 0.9 1.2 6.4 -0.5 -0.9 0.2 -0.2 0.4 1.4 2.5 0.2
Worry (Nagel 2018) 0.8 1.7 5.9 -1.3 -1.6 -0.0 -1.4 -1.2 2.4 0.3 0.0
Alzheimer’s Disease (in mother) 1.1 1.2 3.9 2.0 0.8 -0.5 1.4 1.3 -0.5 -0.8 0.6
Alzheimer’s Disease (in father) 1.1 1.2 3.9 -0.5 0.0 -0.2 -0.8 -0.6 -2.0 -1.9 -1.0
Alzheimer’s Disease (including proxy) 1.0 1.4 2.9 1.7 1.4 -1.0 0.8 1.1 -1.3 -1.1 0.7
Crohns Disease (2017) 0.5 1.1 2.9 -0.3 1.2 -1.7 0.7 1.5 -1.2 -0.1 -0.0
Irritable Bowel Disease (IBD) 1.3 3.2 12.4 0.4 2.0 -3.5 0.8 2.2 -1.6 -0.1 -0.8
Ulcerative Colitis (UC) 1.8 3.3 14.0 1.2 2.1 -3.7 1.0 1.9 -1.0 -0.3 -1.0
Major Depression (MDD) 0.5 0.7 2.7 1.1 1.6 0.0 0.0 0.9 -0.8 0.0 0.0
Reaction Time 0.2 0.4 1.8 0.3 0.1 -0.5 -1.3 1.0 -0.6 -0.1 -0.1
Verbal and Numeric Reasoning (VNR) 3.0 7.1 18.8 -1.8 -3.8 2.2 -0.6 -4.3 3.8 0.1 0.3
Breast Cancer 0.4 0.9 3.2 -0.1 -0.2 -0.3 -0.1 -0.2 -1.7 -1.8 -1.1
Ovarian Cancer 0.6 0.7 1.9 1.1 1.1 -0.1 -1.1 0.6 -0.2 -1.4 0.2
Prostate Cancer 0.8 1.1 3.8 -0.3 0.4 2.0 -1.2 0.3 -0.6 0.0 -1.7
Age at First Birth 0.3 0.5 1.2 1.1 0.5 0.1 0.5 0.3 0.7 1.1 0.7
Bipolar Disorder (2011) 0.9 0.9 3.0 0.9 1.7 -0.1 1.6 0.6 -0.5 0.0 0.0
Body Mass Index (BMI) (2010) 0.4 0.5 1.6 1.3 0.8 0.0 0.9 0.3 -0.6 -0.7 0.5
Coronary Artery Disease (CAD) 0.4 0.5 2.6 -0.7 -0.8 0.2 0.3 -1.6 0.6 0.0 0.0
Crohns Disease (2012) 0.7 1.1 3.2 -0.4 0.4 -1.4 1.8 -0.0 -1.5 -1.1 -0.1
Mean Putamen Volume 0.7 0.8 4.3 -0.7 -0.1 -0.6 -2.1 0.4 -0.1 1.1 -0.1
Fasting Glucose 0.4 0.5 1.8 0.7 0.8 -1.0 -0.0 -0.0 0.3 -0.5 1.3
HbA1C 0.2 0.2 0.8 0.3 -0.4 0.0 0.3 -0.1 -0.9 0.3 0.7
HDL Cholesterol 1.2 2.0 8.8 -3.0 -1.1 1.0 -0.3 -0.5 2.3 0.1 0.2
LDL Cholesterol 0.7 1.1 2.4 1.0 1.2 -1.3 -0.8 0.7 0.0 -1.3 1.5
Lupus 0.8 1.3 3.1 -1.3 -1.8 0.9 -0.4 -0.9 0.6 1.2 1.3
Neuroticism (2016) 0.6 0.9 1.7 1.3 0.6 -1.2 -0.8 0.7 0.8 0.7 1.2
Primary Biliary Cirrhosis 0.4 0.6 2.9 0.6 -0.5 -0.4 1.7 -0.9 -0.0 -0.4 0.0
Rheumatoid Arthritis 1.3 1.8 4.1 -1.8 -1.8 1.0 0.6 -2.0 1.3 -0.9 -0.3
Schizophrenia (2014) 0.7 1.5 3.5 1.7 1.9 -1.0 0.6 1.9 -0.5 -0.0 0.6
Triglycerides 0.2 0.3 1.1 1.0 -0.0 0.0 -0.4 0.2 -0.1 -0.6 0.7
Type 2 Diabetes (T2D) (2012) 0.2 0.2 0.5 0.5 -0.3 -0.4 0.7 -0.4 0.6 0.0 0.0
Ulcerative Colitis 1.1 1.6 9.1 0.7 0.9 -3.0 0.6 0.7 0.3 -1.2 -0.3
Blood Eosinophil Count 0.6 4.3 22.1 -2.4 0.1 -4.7 0.2 1.1 -0.4 1.9 -1.3
Blood Platelet Count 0.1 0.7 2.2 -0.3 -0.2 -0.8 0.7 -0.2 -1.1 -1.5 -1.1
Blood Red Count 0.1 0.7 2.3 -0.2 1.2 -0.7 0.7 0.7 -1.5 -0.3 0.0
Blood White Count 0.1 0.5 1.7 -0.3 -0.4 -0.2 1.2 0.7 -1.3 0.3 0.1
Heel T-Score 0.8 6.1 22.7 1.3 3.2 -2.6 -1.8 4.8 -1.1 0.0 -1.9
BMI 0.5 2.7 13.5 1.1 0.0 -0.5 3.7 -0.0 -1.2 -2.1 0.9
Height 0.1 1.2 4.8 -0.7 0.2 0.7 -0.8 0.2 -0.5 1.7 2.2
Waist Hip Ratio (WHR) 0.1 0.4 2.0 -0.1 -0.1 0.1 -0.3 -1.4 -0.4 -0.8 -0.2
Systolic Blood Pressure 0.5 2.4 7.6 1.1 2.5 -0.6 1.5 0.2 -1.4 -2.8 -0.3
Smoking Status 0.2 0.5 1.9 -0.8 0.7 -0.1 -1.4 0.2 -0.6 0.6 -0.2
Allergy or Eczema 1.4 3.8 25.2 0.6 0.3 -5.0 1.6 -0.4 0.6 -0.1 -1.2
Cardiovascular Disease 0.3 1.0 3.2 -0.5 1.1 -0.0 1.8 0.6 -1.4 0.3 1.1
Hypothyroidism (self reported) 0.2 0.5 1.6 -1.0 -0.8 -0.4 0.8 -1.3 0.1 0.2 0.3
Respiratory disease 1.4 3.0 19.9 1.2 0.4 -4.5 0.5 0.5 -1.1 -0.3 1.1
Type 2 Diabetes (T2D) (2018) 0.2 0.4 1.8 -0.8 -0.6 -0.7 0.1 -0.1 -0.0 1.3 0.4
Lung FEV1/FVC ratio 0.8 4.0 17.5 1.1 1.8 1.6 1.6 1.5 -4.2 -1.7 -0.1
Lung FVC 0.1 0.6 2.2 0.9 -0.1 -0.2 0.9 0.5 0.3 0.6 -1.5
Neuroticism 0.1 0.4 0.9 -0.6 -0.9 -0.8 -0.1 -0.9 0.3 0.5 0.0
Chronotype (morning person) 0.4 1.0 2.5 -0.6 -0.2 1.1 1.6 0.7 -0.6 1.3 1.3
Hair Pigment 0.0 0.7 1.7 -1.2 -0.3 1.0 -0.1 -0.1 -1.3 -0.6 0.8
Tanning 0.1 0.7 3.4 -0.5 -0.6 1.8 0.3 -0.1 -0.9 0.8 -0.2
Hand grip strength (left) 0.8 2.1 10.5 3.2 0.3 1.5 1.0 0.1 -0.3 -1.5 -0.7
Number of treatments/medications taken 0.9 1.6 6.3 0.4 0.9 -2.5 1.9 0.7 -1.0 -0.3 0.4
Average weekly spirits intake 1.0 1.3 3.7 1.1 0.6 1.8 -0.8 0.5 -0.9 -1.9 0.1
Sensitivity / hurt feelings 0.5 0.9 2.0 -0.9 -0.8 -0.1 1.1 -1.1 -0.6 -0.8 -1.4
Frequency of depressed mood in last 2 weeks 0.2 0.3 0.6 -0.4 -0.8 -0.2 0.6 -0.7 0.2 0.5 0.8
Hearing difficulty/problems: Yes 0.5 0.8 2.2 1.1 0.5 -1.3 1.5 0.6 -0.5 0.4 -0.0
Relative age of first facial hair 1.3 2.6 8.4 2.9 1.4 -2.1 -0.6 1.9 -1.1 -0.5 -0.7
Other serious medical condition/disability diagnosed by doctor 0.2 0.2 0.5 0.0 0.5 -0.5 0.1 0.7 0.6 0.5 0.4
Ever used hormone-replacement therapy (HRT) 0.8 1.0 4.1 -0.0 0.7 0.8 -0.2 2.0 -0.9 1.0 1.0
Ever had hysterectomy (womb removed) 0.9 1.0 2.2 1.5 0.4 -1.3 0.7 1.0 0.2 0.6 1.5
Systolic blood pressure, automated reading 0.6 1.7 6.1 1.5 1.4 0.5 1.0 0.5 -1.4 -2.5 -0.2
Eye problems/disorders: Diabetes related eye disease 0.4 0.4 2.0 -0.9 -0.3 0.5 -1.4 -0.2 0.1 -0.1 0.1
Angina 0.5 0.6 2.5 -0.2 -0.5 -1.0 0.7 0.4 0.8 1.6 0.4
Medication for hormone replacement therapy 0.5 0.5 3.1 -0.3 0.4 -0.7 -0.0 -0.4 -0.0 -1.8 -0.3
Vitamin and mineral supplements 0.5 0.7 2.4 -1.1 -0.6 -0.8 0.6 0.2 0.5 -0.7 -1.6
Supplements: Zinc 1.6 1.7 3.8 1.5 1.5 -1.1 -0.2 1.9 -1.4 -1.3 -0.6
Medication: Co-codamol 0.3 0.4 1.9 -0.6 0.4 -1.4 -0.5 -0.1 0.3 0.0 0.0
Medication: Metformin 0.3 0.5 1.4 -1.0 -0.9 -1.2 0.1 0.0 0.6 -0.2 -0.5
Diabetes (father) 0.6 0.7 3.7 -0.2 0.6 -0.0 -0.2 1.9 -0.6 0.9 -0.3
Diabetes (mother) 0.3 0.4 1.0 0.0 0.8 -0.7 1.0 0.6 -0.5 -0.3 -0.7
Severe depression (siblings) 0.4 0.4 1.3 1.0 0.4 0.3 0.2 -0.2 0.8 -1.1 0.5
Pack years adult smoking proportion 0.2 0.3 1.1 0.3 -0.1 -1.1 -0.2 0.5 -0.6 0.5 0.8
Impedance of leg (right) 0.3 1.3 4.5 -0.8 -0.7 -0.1 -1.9 -1.0 2.1 0.0 0.1
Leg fat-free mass (left) 0.2 1.2 5.6 0.8 0.2 -0.0 2.4 0.0 -1.2 -1.0 0.9
Trunk fat percentage 0.5 2.2 10.6 0.6 -0.1 -1.3 3.3 -0.5 -0.2 -1.4 1.6
Hand grip strength (right) 0.7 1.8 7.0 2.6 1.2 1.1 0.3 0.6 -0.5 -2.0 -0.5
Townsend deprivation index at recruitment 0.4 0.5 1.5 -0.1 0.5 -0.5 0.8 0.9 1.2 -0.2 -0.8
Current tobacco smoking 1.3 2.1 6.5 0.7 1.7 -2.5 -0.7 1.9 -1.6 -0.3 -0.1
Average weekly fortified wine intake 0.7 0.8 1.8 -0.9 -1.0 0.2 -1.4 -1.1 0.7 -0.9 -0.2
Maternal smoking around birth 0.5 0.8 2.6 -1.2 -0.6 0.1 -0.4 0.1 1.6 0.2 -1.2
Fed-up feelings 0.4 0.6 1.6 -0.5 0.0 -1.2 0.4 -0.7 0.3 -1.3 -1.1
Frequency of unenthusiasm / disinterest in last 2 weeks 0.1 0.1 0.4 -0.6 -0.2 -0.0 -0.5 0.2 -0.0 0.2 0.4
Relative age voice broke 1.1 1.6 5.4 2.1 0.9 -1.1 -2.3 0.9 0.3 -0.3 -0.3
Taking other prescription medications 1.1 1.6 4.5 -0.5 -1.2 -1.8 0.0 -0.9 1.4 0.9 2.1
Age when periods started (menarche) 0.7 1.6 9.0 0.9 1.2 0.4 0.7 -0.5 -0.9 0.1 3.0
Bilateral oophorectomy (both ovaries removed) 0.4 0.5 2.2 -1.5 -1.0 0.4 0.7 0.1 -0.1 0.5 0.1
Heel bone mineral density (BMD) T-score, automated (left) 0.8 1.9 4.7 -0.2 0.8 -1.4 -2.1 1.7 -0.2 0.7 -2.2
Tinnitus: Yes, but not now, but have in the past 0.6 0.7 2.9 -1.1 0.4 -1.7 -0.7 0.1 -0.2 -0.5 -0.3
Qualifications: CSEs or equivalent 1.2 1.5 6.5 -1.3 -1.2 0.5 0.2 -0.8 0.6 1.2 2.5
Serious illness, injury or assault to yourself 2.2 2.7 8.9 1.5 0.6 -1.0 3.0 0.8 0.6 1.9 2.0
High blood pressure 0.6 1.6 6.2 0.4 1.1 -0.4 1.6 1.3 -2.5 0.7 0.4
Hayfever, allergic rhinitis or eczema 0.9 2.0 11.4 -0.5 -0.4 -3.4 1.5 -1.1 0.4 0.6 -0.3
Multivitamins +/- minerals 0.7 0.9 2.9 0.5 0.7 0.9 -1.4 0.0 -0.6 0.6 1.7
Stomach or abdominal pain in last month 0.9 1.1 3.1 -0.2 1.2 0.4 -0.3 1.8 -1.3 1.3 -0.7
Supplements: Glucosamine 0.9 1.2 4.9 2.2 -0.4 0.8 -1.6 -0.4 0.2 0.2 1.0
Diverticular disease/diverticulitis (self-reported) 2.3 2.7 6.7 2.4 2.6 -1.5 0.2 2.0 0.5 -1.2 -1.1
Medication: Atenolol 2.0 2.5 5.9 1.1 2.0 -1.7 2.4 1.1 -1.5 -0.2 -1.6
Medication: Levothyroxine sodium 0.0 0.1 0.4 -0.6 -0.1 0.1 0.0 -0.0 -0.1 0.4 -0.2
Sitting height 0.1 0.4 2.2 -1.5 0.6 0.0 -0.0 -0.2 -0.0 -0.2 0.7
Chronic bronchitis/emphysema (father) 0.5 0.6 1.7 -1.1 -0.8 -0.7 -0.2 -0.3 0.8 1.3 -0.2
High blood pressure (mother) 0.8 1.1 2.4 0.1 1.3 -1.5 1.3 0.4 0.1 1.2 1.2
Body mass index (BMI) 0.5 2.1 8.6 1.5 0.2 -0.5 2.9 0.1 -0.9 -1.7 1.4
Impedance of leg (left) 0.2 0.9 3.7 -0.6 -0.4 -0.2 -1.6 -0.4 1.9 0.3 0.2
Leg predicted mass (left) 0.2 1.2 5.6 0.8 0.2 -0.0 2.4 -0.0 -1.1 -1.0 0.9
Trunk fat mass 0.5 2.2 9.9 0.8 -0.1 -0.9 3.1 -0.5 -0.5 -1.6 1.8
Waist circumference 0.4 1.4 4.2 0.8 -0.0 -1.4 2.1 -0.3 -0.4 -1.2 1.5
Number of incorrect matches in round 0.3 0.6 2.7 0.5 0.9 -0.4 -0.3 0.6 0.2 -1.6 -0.3
Past tobacco smoking 0.4 0.7 1.9 0.8 0.7 -0.6 0.9 1.1 -0.3 -0.4 1.4
Alcohol usually taken with meals 0.3 0.4 1.0 -0.7 -0.8 0.8 -0.6 -1.0 -0.4 0.1 0.1
Nervous feelings 0.3 0.6 2.9 -0.4 -0.5 -0.5 -1.7 -0.3 1.1 0.1 0.3
Frequency of tenseness / restlessness in last 2 weeks 0.5 0.7 2.1 -0.1 -0.5 -1.4 -1.2 0.1 1.4 0.3 0.0
Hearing difficulty/problems with background noise 0.6 0.9 3.8 1.4 0.2 -1.0 2.0 0.0 0.8 -0.1 0.3
Hair/balding pattern: Pattern 2 1.2 1.6 7.2 0.2 1.8 -2.7 -0.0 1.2 -0.2 -0.6 0.6
Had menopause 0.3 0.4 1.8 -0.7 -0.5 0.1 -0.7 -0.2 0.6 1.3 0.3
Had other major operations 0.7 0.8 2.1 -0.6 1.0 -0.1 1.2 1.4 -0.3 0.9 -0.8
Forced vital capacity (FVC) 0.1 0.2 0.8 0.1 0.1 0.5 -0.2 0.2 0.8 -0.3 -0.9
Heel bone mineral density (BMD) T-score, automated (right) 0.9 2.1 6.5 0.2 1.6 -1.3 -2.5 2.3 -0.6 0.4 -0.8
Ever unenthusiastic/disinterested for a whole week 0.7 0.8 1.8 -1.2 -0.1 -0.8 -1.0 1.3 -0.4 0.2 -1.3
Qualifications: None of the above 0.4 0.9 2.4 0.2 1.3 -1.6 0.6 1.3 -0.9 0.4 0.5
Financial difficulties in last 2 years 0.5 0.6 3.3 0.2 -0.1 1.8 0.4 0.5 -0.1 1.1 -0.4
Mouth/teeth dental problems 0.3 0.5 1.7 -0.1 1.3 -0.0 0.7 0.3 -0.9 -0.8 0.4
Heart attack 0.9 1.2 5.4 -0.5 0.8 -2.3 0.1 0.5 -1.6 0.6 -0.1
Allergy 1.7 3.8 28.7 -0.0 -0.4 5.4 -0.5 -0.2 -0.4 -1.1 -0.1
Pain all over the body in last month 0.4 0.4 1.2 -0.1 -0.7 0.2 0.7 0.1 1.1 0.9 -0.6
Diabetes (self-reported) 0.4 0.7 1.6 -0.9 -0.7 -1.3 0.4 -0.5 1.1 0.7 0.7
Hayfever/allergic rhinitis (self-reported) 1.0 1.3 8.7 0.5 0.8 -2.9 0.1 0.1 -0.6 0.2 -0.3
Medication: Ramipril 0.6 0.7 4.5 -0.2 -0.2 -0.0 2.1 -0.1 -0.7 0.0 -0.9
Medication: Simvastatin 1.3 1.9 4.6 -1.2 -1.9 0.1 2.1 -1.6 1.3 1.0 0.8
Fluid intelligence score 2.2 4.7 10.8 -1.4 -2.9 2.2 0.5 -3.3 3.3 0.5 0.3
Illnesses of siblings 1.7 2.3 5.4 -1.2 -0.7 1.7 -2.2 0.9 1.6 2.3 0.7
Neuroticism score 0.3 0.7 1.9 -1.0 -0.4 -0.6 -1.4 -0.1 0.9 1.2 0.1
Weight 0.4 1.8 7.1 1.2 0.2 -0.4 2.7 -0.2 -0.8 -1.4 1.7
Impedance of arm (right) 0.4 1.9 5.3 -2.3 -1.2 -0.8 -0.3 -1.4 1.8 1.7 -0.1
Arm fat percentage (right) 0.5 2.0 9.3 0.7 -0.4 -0.9 3.0 -0.8 -0.4 -1.6 1.5
Trunk fat-free mass 0.2 1.0 2.2 1.5 0.3 0.5 1.4 -0.0 -1.3 -1.4 0.3
Hip circumference 0.5 1.9 6.5 0.6 0.2 -1.2 2.5 -0.6 0.0 -1.9 1.7
Time employed in main current job 0.6 0.7 2.7 1.0 1.7 -0.6 0.6 0.8 -0.4 -0.1 -0.5
Alcohol intake versus 10 years previously 1.7 2.5 7.4 -2.3 0.7 0.3 -1.6 1.0 -1.5 2.7 1.0
Father’s age at death 0.2 0.3 0.9 -0.2 0.0 0.9 0.2 0.0 0.5 0.6 1.0
Worrier / anxious feelings 0.8 1.5 3.5 -1.8 -0.6 0.4 -1.8 -1.0 1.9 0.5 -0.1
Frequency of tiredness / lethargy in last 2 weeks 0.1 0.1 0.5 -0.4 0.2 -0.2 -0.0 -0.1 0.1 -0.7 -0.1
Falls in the last year 0.6 0.8 2.0 -0.6 0.4 1.2 1.2 0.4 -0.5 0.9 1.4
Hair/balding pattern: Pattern 3 2.3 3.4 13.7 -2.4 -1.7 3.7 -0.6 -1.4 1.5 0.2 -0.1
Number of live births 0.7 0.9 2.2 0.7 -0.1 -1.5 1.3 1.1 0.7 1.1 0.5
Forced expiratory volume in 1-second (FEV1) 0.1 0.4 1.4 0.5 0.3 1.2 0.1 -0.1 0.2 -0.9 -0.9
Pulse rate 1.7 2.9 5.8 2.4 2.1 -0.4 -0.6 2.3 -1.5 -2.2 0.8
Happiness 0.4 0.5 1.3 -1.1 -1.0 0.2 -0.3 -0.9 1.0 -0.1 0.2
Noisy workplace 1.5 1.9 3.1 1.7 1.7 -1.3 1.3 1.0 -1.2 -1.8 0.4
Qualifications: A levels/AS levels or equivalent 1.5 3.3 7.4 -1.9 -2.6 1.9 -2.7 -1.8 0.6 0.6 -1.1
Serious illness, injury or assault of a close relative in last 2 years 2.7 3.1 8.3 2.9 2.5 -2.0 0.5 1.1 -0.3 -2.1 0.6
Mouth/teeth dental problems: Dentures 0.2 0.4 1.6 -0.2 -0.4 -0.9 0.1 0.7 0.1 1.3 0.0
Asthma 2.3 4.6 28.4 1.8 1.1 -5.3 1.0 1.4 -0.8 -0.6 0.3
Medication: Ibuprofen (e.g. Nurofen) 1.3 1.6 3.9 1.8 2.0 -1.6 -0.2 1.5 -0.4 -0.3 -0.7
Medication: Cholesterol lowering 0.6 0.9 3.5 -0.2 0.5 -1.9 1.7 -0.1 0.0 0.5 0.0
Depression (self-reported) 0.5 0.6 1.5 -0.9 -1.1 -0.7 -1.2 -0.9 -0.0 0.4 -0.4
Medication: Lansoprazole 0.4 0.4 1.2 -1.1 -1.0 0.7 0.1 0.0 0.4 0.6 -0.5
Prospective memory result 2.0 2.4 4.8 -0.2 1.9 -1.9 2.2 1.4 -2.0 -0.8 -0.7
Lung cancer (father) 1.3 1.5 5.5 0.6 0.6 0.3 0.7 0.9 -2.4 -0.5 -2.1
Illnesses of mother 1.1 1.4 3.3 -0.9 -1.1 1.5 -1.8 -0.2 1.6 0.4 -0.8
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.3 0.8 -0.1 0.5 0.9 -0.4 -0.4 -0.3 -0.3 -0.9
Pulse wave Arterial Stiffness index 0.3 0.3 0.8 -0.9 0.2 0.9 -0.0 -0.1 -0.9 -0.2 -0.2
Impedance of arm (left) 0.4 2.0 6.7 -2.6 -1.2 -0.4 -0.1 -1.4 1.8 1.6 -0.2
Arm fat mass (right) 0.5 2.1 9.5 1.2 -0.1 -0.6 3.1 -0.5 -0.9 -1.9 1.1
Trunk predicted mass 0.2 1.1 2.3 1.5 0.3 0.6 1.4 0.0 -1.3 -1.5 0.3
Standing height 0.0 0.2 0.6 -0.7 -0.2 0.4 -0.0 -0.8 0.1 0.4 0.7
Length of working week for main job 1.0 1.2 5.7 1.3 0.9 -0.3 0.8 0.1 -0.5 -2.4 0.3
Exposure to tobacco smoke at home 0.4 0.5 2.1 -0.1 0.4 0.8 -0.0 1.5 0.1 -0.5 -0.8
Breastfed as a baby 1.6 2.0 5.4 1.8 2.3 -0.5 0.2 2.2 -1.2 -0.7 0.2
Tense / ‘highly strung’ 1.0 1.7 6.2 -0.8 -1.8 -0.1 -0.7 -0.9 2.5 0.7 1.3
Seen doctor (GP) for nerves, anxiety, tension or depression 0.9 1.3 5.2 0.4 0.8 -2.3 -0.8 0.5 0.9 -1.3 1.1
Hair/balding pattern: Pattern 4 0.3 0.7 1.8 0.7 0.5 -1.2 -0.4 -0.1 -1.4 -1.3 0.1
Birth weight of first child 0.4 0.8 1.3 1.0 0.4 1.0 0.4 1.1 -1.1 1.0 0.3
Peak expiratory flow (PEF) 0.2 0.4 1.0 0.7 1.0 0.8 0.1 0.4 0.4 -0.5 -0.2
Pulse wave reflection index 0.5 0.6 2.4 -0.9 -0.2 -0.1 1.6 -0.4 -0.8 0.4 -0.6
Ever highly irritable/argumentative for 2 days 0.7 0.8 1.7 -1.2 0.5 -1.0 -0.8 0.7 1.3 0.9 -0.2
Loud music exposure frequency 0.3 0.4 1.6 -0.3 0.3 -0.5 -0.1 -0.4 1.3 -0.2 0.9
Qualifications: O levels/GCSEs or equivalent 0.2 0.4 1.3 0.2 -0.6 0.6 -0.1 -1.2 -0.4 -0.6 -0.4
Mouth/teeth dental problems: Bleeding gums 0.8 1.0 2.0 -0.6 -0.8 0.5 -1.2 -1.4 -0.5 -1.1 -1.3
Blood clot in the leg (DVT) 0.9 1.2 2.7 0.7 1.0 -1.6 -1.4 0.3 1.6 0.7 0.8
Medication: Paracetamol 1.2 2.0 4.7 1.6 2.2 -1.8 0.2 2.1 -0.8 -0.1 0.1
Headache pain in last month 0.5 0.8 3.2 -1.0 0.4 -0.5 -0.8 1.1 -0.5 1.8 0.2
Medication for cholesterol, blood pressure or diabetes 0.7 1.1 3.0 -0.3 -1.2 1.7 -1.6 -0.2 0.4 0.8 -0.7
Glaucoma (self-reported) 0.6 0.8 3.2 0.4 -1.8 0.1 -1.1 -0.7 -0.1 -0.2 1.0
Gout (self-reported) 0.5 0.7 1.3 -0.8 -0.1 0.2 1.1 0.8 -1.1 -0.6 -1.0
Hypothyroidism/myxoedema (self-reported) 0.1 0.2 0.5 -0.6 -0.2 -0.0 0.3 -0.5 -0.4 0.2 0.7
Medication: Amlodipine 1.1 1.6 4.2 1.3 0.9 -0.8 1.8 0.3 -2.1 -0.7 1.2
Medication: Ventolin 100micrograms inhaler 2.7 3.5 15.9 1.2 1.7 -4.0 1.2 1.3 -1.0 -1.8 0.4
Birth weight 0.7 1.5 4.8 1.1 0.3 2.2 -0.3 1.5 -0.8 1.3 1.0
Chronic bronchitis/emphysema (mother) 0.7 0.8 1.8 -0.2 -1.2 -1.0 1.3 -0.9 -0.1 0.9 0.5
High blood pressure (siblings) 1.0 1.4 4.6 0.4 0.7 -0.1 1.4 0.2 -2.1 -1.9 -0.5
Forced vital capacity (FVC), Best measure 0.1 0.2 0.4 -0.5 -0.2 0.1 -0.4 -0.7 0.6 0.4 -0.6
Body fat percentage 0.6 2.3 9.1 0.7 -0.3 -1.2 3.0 -0.5 -0.0 -1.6 2.1
Leg fat percentage (right) 0.5 1.9 4.7 1.0 -0.3 -0.9 1.9 -0.6 0.2 -2.2 2.0
Arm fat-free mass (right) 0.2 1.2 2.4 1.6 0.7 -0.1 1.4 0.7 -1.4 -1.4 0.5
Exposure to tobacco smoke outside home 0.7 0.9 2.0 1.4 1.1 -0.2 0.8 0.9 0.6 1.4 0.6
Comparative body size at age 10 0.4 1.0 2.0 0.7 -1.2 0.6 1.1 -1.1 1.2 -0.3 1.4
Number of full brothers 0.6 0.7 2.3 -0.1 0.4 -0.5 1.3 -0.1 -1.5 -0.4 -1.2
Worry too long after embarrassment 0.4 0.8 2.8 -1.1 -1.7 0.2 0.5 -0.4 0.3 0.7 -1.0
Seen a psychiatrist for nerves, anxiety, tension or depression 0.7 0.9 2.6 -0.5 -0.2 -1.6 -1.1 -0.3 1.0 -0.2 1.4
Wheeze or whistling in the chest in last year 0.8 1.3 8.3 0.4 0.7 -2.9 0.6 0.2 0.7 -0.9 0.2
Number of children fathered 1.1 1.2 6.1 -0.7 -0.8 1.6 0.0 -0.1 -0.2 -0.4 -2.5
Reason for reducing amount of alcohol drunk: Health precaution 0.4 0.5 1.0 1.0 1.0 0.2 0.8 0.4 -0.7 -0.9 -0.1
Age at first live birth 0.3 0.5 1.2 0.2 -0.9 0.0 -1.1 -0.8 1.1 0.2 -0.5
Pulse wave peak to peak time 0.3 0.3 1.4 0.8 -0.4 -0.6 0.1 -0.0 1.2 0.3 0.1
Health satisfaction 0.2 0.2 0.8 0.4 -0.1 -0.1 -0.5 0.6 -0.9 -0.3 -0.3
Shortness of breath walking on level ground 2.0 2.4 7.7 1.4 1.8 -2.8 -1.0 1.5 -1.0 -1.2 0.6
Qualifications: College or University degree 0.4 1.3 2.5 -1.2 -1.5 0.8 -1.0 -1.6 1.5 0.2 0.1
Eye problems/disorders: None of the above 0.2 0.2 0.6 -0.7 -0.2 0.3 -0.2 -0.6 -0.4 0.4 -0.8
Mouth/teeth dental problems: Loose teeth 0.7 0.8 2.4 1.0 0.3 -1.0 0.0 -0.2 1.6 -1.3 0.6
Emphysema/chronic bronchitis 0.5 0.6 2.4 0.7 0.3 -1.1 0.2 -0.3 -0.5 0.0 1.6
Medication for pain relief, constipation, heartburn 1.5 2.6 6.5 -1.2 -1.9 2.5 -2.0 -1.6 1.1 0.7 0.9
Neck or shoulder pain in last month 0.4 0.5 1.6 0.7 1.0 -0.0 -0.4 1.2 -0.8 -0.3 -0.6
Medication: Blood pressure 0.8 1.5 3.8 0.4 1.3 -1.6 1.9 0.5 -1.3 -1.2 0.4
Angina (self-reported) 0.5 0.7 3.1 -0.2 -0.5 -0.9 0.6 0.2 0.8 1.8 0.4
Migraine (self-reported) 0.9 1.1 4.3 -0.4 0.1 -0.8 -1.1 0.8 1.4 2.1 -0.2
Medication: Ibuprofen 1.1 1.3 3.5 1.4 1.9 -1.1 0.2 1.5 -0.4 0.0 -0.9
Medication: Allopurinol 0.9 1.3 3.9 -0.5 1.1 -0.2 0.8 1.3 -1.3 -2.0 -0.7
Medication: Omeprazole 0.9 1.1 3.9 -1.2 -1.4 0.3 0.6 -2.0 0.6 0.5 0.3
Medication: Seretide 50 evohaler 0.6 0.7 1.9 0.4 1.1 -1.4 -0.1 0.8 0.2 -0.9 -1.1
Mean time to correctly identify matches 0.2 0.3 1.3 -0.2 -0.8 0.0 -0.6 0.3 -1.2 -0.3 -0.3
Heart disease (mother) 0.6 0.8 2.0 -1.2 0.3 -0.0 1.0 1.4 -0.7 1.0 -0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.0 1.2 5.4 1.2 -0.3 0.4 -0.3 -0.8 0.6 -2.3 -1.2
Whole body fat mass 0.6 2.3 9.2 0.8 -0.0 -0.8 3.0 -0.5 -0.5 -1.6 2.2
Leg fat mass (right) 0.6 2.3 6.1 1.3 0.0 -1.0 2.5 -0.3 -0.5 -2.1 2.1
Arm predicted mass (right) 0.2 1.0 1.9 1.4 0.6 0.4 1.3 0.6 -1.1 -1.3 0.5
Pulse rate, automated reading 1.1 3.7 8.8 2.4 3.0 -0.0 1.0 2.6 -1.9 -1.1 1.4
Alcohol intake frequency. 1.0 2.4 6.8 -0.2 2.4 -1.3 -1.1 2.6 -1.3 1.4 -0.2
Comparative height size at age 10 0.2 0.9 5.7 -2.4 -0.3 -0.3 -0.3 -0.3 1.1 0.5 -0.5
Number of full sisters 0.3 0.3 1.2 0.4 1.1 -0.6 -0.2 -0.1 0.2 0.4 0.8
Suffer from ‘nerves’ 0.8 1.3 2.8 -0.8 -1.5 0.8 -1.6 -0.7 1.1 1.7 0.4
Overall health rating 0.4 0.8 2.7 -1.1 -0.4 -0.8 -0.7 0.5 -0.9 1.7 -0.5
Chest pain or discomfort 0.3 0.4 1.5 0.1 -0.3 0.4 1.2 0.4 0.8 0.1 0.7
Had major operations 0.4 0.5 1.6 0.6 0.8 -0.0 0.3 0.5 -0.4 1.3 0.8
Age at last live birth 0.3 0.5 1.2 1.1 0.5 -0.9 -0.0 0.4 1.1 0.2 0.3
Family relationship satisfaction 0.6 0.8 3.6 0.3 0.7 -0.1 0.1 0.9 -1.9 -1.1 0.5
Leg pain on walking 1.4 1.8 3.0 1.3 1.3 -1.7 1.7 1.7 -1.3 -0.9 -0.1
Qualifications: NVQ or HND or HNC or equivalent 0.9 1.1 3.5 1.9 0.1 0.4 0.1 -0.8 -0.9 -1.9 -0.2
Commuting to job workplace: Car/motor vehicle 1.3 1.5 3.4 0.8 1.4 -0.8 -1.8 1.1 -0.5 -1.8 -0.7
Illness, injury, bereavement, stress in last 2 years 1.1 1.4 4.4 -2.1 -1.0 0.7 -2.1 -0.2 -0.4 0.1 -0.6
Medication: Aspirin 0.8 1.1 4.4 -0.8 -1.2 0.1 2.1 -0.6 -1.2 -0.3 -0.4
Supplements: Vitamin C 0.3 0.4 0.9 -0.1 1.0 -0.8 0.5 0.3 0.7 0.5 0.6
Knee pain experienced in last month 0.7 1.1 4.1 1.8 -0.0 0.4 -0.4 2.0 -0.2 0.1 -1.2
Hypertension (Self-reported) 0.5 1.5 4.8 0.4 0.7 -0.3 2.0 1.2 -2.2 0.9 0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.7 0.8 2.0 -0.6 -1.2 -0.7 0.8 -1.0 1.4 0.3 0.5
Illnesses of father: Heart disease 0.3 0.4 1.3 0.5 1.1 0.1 0.9 0.7 0.6 -0.3 -0.3
Illnesses of siblings: Diabetes 0.7 0.9 1.7 -1.3 -0.5 -1.3 0.6 -1.1 0.0 -0.9 -0.9
Smoking status: Previous 0.7 1.0 2.2 -1.1 -0.6 1.5 -0.7 -1.0 0.6 1.3 -1.0
Forced expiratory volume in 1-second (FEV1), predicted 0.4 0.9 2.7 -1.0 0.6 -0.2 -1.6 1.1 -0.4 0.0 -1.4
Whole body fat-free mass 0.2 1.1 3.2 1.3 0.3 0.2 1.8 0.2 -1.3 -1.2 0.5
Leg fat-free mass (right) 0.2 1.1 5.2 0.7 0.4 0.0 2.3 0.3 -1.4 -0.7 0.7
Arm fat percentage (left) 0.5 1.9 8.8 0.6 -0.4 -0.7 3.0 -0.8 -0.4 -1.6 1.6
Average weekly red wine intake 0.6 0.8 4.2 0.4 -1.1 0.5 -0.3 -2.0 0.8 -0.2 -0.1
Handedness (chirality/laterality): Left-handed 0.4 0.5 2.4 0.8 0.2 -0.1 1.6 0.2 -0.7 -0.4 -0.3
Mood swings 0.6 1.2 4.4 -0.0 1.3 -2.1 -0.2 0.6 0.8 -1.2 -0.9
Loneliness, isolation 0.9 1.2 2.7 -1.6 -0.9 -1.6 -0.5 0.1 0.7 1.6 0.4
Long-standing illness, disability or infirmity 0.4 0.6 2.4 0.8 0.2 -1.6 0.9 0.8 -0.5 0.2 -0.1
Ever had bowel cancer screening 0.6 0.7 2.2 -1.1 -0.9 -0.3 -1.5 0.1 0.2 0.3 -1.3
Diabetes diagnosed by doctor 0.5 0.8 3.6 -0.8 -0.3 -1.9 0.5 0.0 0.3 0.5 1.1
Ever had stillbirth, spontaneous miscarriage or termination 0.4 0.4 1.3 -0.2 -0.4 0.2 1.0 -0.3 1.1 0.7 0.3
Friendships satisfaction 0.1 0.2 0.5 0.4 -0.3 0.5 0.4 0.3 -0.7 -0.1 -0.4
Qualifications: nursing, teaching 0.8 1.2 2.6 -1.2 -0.8 1.1 -0.5 -1.4 -1.2 -0.3 -1.6
Commuting to job workplace: Walk 0.6 0.7 1.8 -0.8 -0.8 -0.0 0.7 -1.1 1.3 0.7 -0.1
Eye problems/disorders: Cataract 0.8 0.9 2.4 1.5 1.2 -1.0 0.7 1.4 -0.3 0.0 0.4
Mouth/teeth dental problems: Mouth ulcers 0.2 0.4 1.6 0.7 -0.3 0.5 -0.4 -0.5 0.1 1.3 -0.3
Medication for cholesterol 0.9 1.4 4.8 1.4 0.5 -1.1 -2.2 -0.6 1.4 -0.9 -0.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.4 1.6 3.2 1.4 1.8 -0.6 -0.2 1.6 -1.6 -0.4 1.5
Back pain experienced in last month 1.2 1.8 7.3 0.6 0.4 -0.7 0.8 1.0 -0.1 2.7 2.1
Mineral and other dietary supplements 1.8 2.4 9.1 -3.0 -0.5 0.6 1.9 -0.7 0.7 -0.1 -2.2
Breast cancer (self-reported) 1.3 1.6 2.9 1.3 1.5 1.1 0.2 1.7 -1.6 -0.4 1.3
Asthma (self-reported) 1.8 3.6 22.8 1.4 0.8 -4.8 0.5 1.4 -0.8 -0.4 0.1
Osteoporosis (self-reported) 0.6 0.8 2.1 0.0 -0.8 1.3 -0.6 -0.5 1.4 1.0 0.5
Osteoarthritis (self-reported) 1.1 1.4 3.2 1.6 1.2 1.2 0.4 1.8 0.4 1.0 1.0
Medication: Aspirin 0.8 1.0 4.5 -0.7 -1.2 0.2 2.1 -0.3 -1.1 0.1 -0.4
Medication: Gliclazide 0.3 0.4 0.7 0.8 0.5 -0.8 0.5 0.9 0.3 -0.2 -0.5
Illnesses of father: None of the above (group 1) 1.6 1.9 3.8 1.7 0.4 -0.9 -1.3 0.1 -1.9 -1.6 -1.9
Smoking status: Current 1.1 1.8 7.0 0.4 1.6 -2.6 -0.6 1.4 -1.5 -0.3 0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.3 1.6 -0.2 0.5 0.3 -0.0 -0.7 0.2 -1.3 0.4
Whole body water mass 0.2 1.3 3.4 1.5 0.5 0.1 1.9 0.3 -1.4 -1.4 0.5
Leg predicted mass (right) 0.2 1.2 5.7 0.7 0.3 0.1 2.4 0.3 -1.3 -0.7 0.8
Arm fat mass (left) 0.6 2.5 10.3 1.2 0.1 -0.9 3.2 -0.4 -1.1 -2.1 1.2
Number of self-reported non-cancer illnesses 0.7 1.3 6.2 -0.4 -0.2 -2.5 1.2 0.8 -0.6 1.0 0.7
Average weekly champagne plus white wine intake 0.9 1.2 3.6 -1.9 -1.0 1.4 0.9 -0.8 -0.5 -0.7 -0.9
Miserableness 0.4 0.6 2.1 -0.4 0.4 -1.1 -0.2 -1.1 1.5 -0.3 0.4
Guilty feelings 0.3 0.5 1.3 0.6 0.1 -1.2 1.1 0.7 0.2 0.6 -0.2
Wears glasses or contact lenses 1.9 2.1 7.2 -2.7 -2.1 0.3 -1.3 -1.6 0.9 0.7 -0.1
Ever taken oral contraceptive pill 0.6 0.6 1.4 0.0 1.1 1.0 0.5 0.4 -1.2 -0.9 -0.5
Hearing aid user 0.7 0.8 2.5 -0.6 0.9 -0.2 -1.2 0.3 0.3 -1.6 -0.9
Mother’s age at death 0.4 0.5 1.3 -0.4 -1.1 0.6 0.5 -0.5 0.6 1.0 -0.5
Financial situation satisfaction 0.6 0.7 1.8 -0.7 -0.3 1.3 0.4 -0.2 0.6 0.9 1.3
Tinnitus: Yes, now most or all of the time 2.0 2.3 9.5 1.3 3.1 -0.6 1.6 1.7 -0.9 -0.1 -0.4
Commuting to job workplace: Public transport 0.6 0.7 1.8 0.2 -1.0 -0.5 1.3 -0.5 0.9 1.3 0.4
Eye problems/disorders: Glaucoma 0.7 0.8 3.6 0.0 -1.9 0.6 -0.4 -0.7 -0.1 0.8 1.2
Medication: Blood pressure 0.7 1.4 4.6 0.1 -0.2 0.6 2.1 1.1 -1.8 1.2 -0.3
Pain type(s) experienced in last month: Hip pain 2.1 2.6 6.4 2.5 2.5 -1.4 -0.2 2.2 -0.8 -1.0 -0.1
Supplements: Fish oil (including cod liver oil) 1.5 1.9 5.8 2.4 0.3 -0.1 -1.9 1.2 -1.2 0.1 1.8
High cholesterol (Self-reported) 0.8 1.5 8.1 -0.9 -0.2 -0.1 2.8 -0.7 -0.3 0.5 1.4
Medication: Bendroflumethiazide 0.5 0.7 3.4 0.1 0.6 0.3 1.8 1.1 0.3 0.6 -0.5
Medication: Paracetamol 1.4 2.2 5.1 1.7 2.2 -1.3 1.1 2.3 -1.3 -0.7 -0.2
Medication: Lisinopril 1.0 1.3 4.0 -1.8 -0.9 -0.5 0.8 -0.2 0.3 2.0 -1.3
Medication: Atorvastatin 6.3 7.7 24.1 1.4 4.9 -2.0 0.4 4.9 -2.7 -0.3 -0.2
Illnesses of father: High blood pressure 0.8 1.0 3.5 -0.0 1.0 1.9 0.7 1.5 -0.1 -0.3 0.7
Alcohol drinker status: Never 0.5 0.6 2.0 0.8 -0.3 0.4 0.8 1.0 -0.1 1.4 0.3
Ever smoked 0.7 1.1 4.0 -0.6 -0.3 0.9 -1.6 0.2 -1.1 -0.0 -2.0
Basal metabolic rate 0.2 1.3 4.6 1.4 0.4 0.1 2.1 0.1 -1.3 -1.4 0.7
Leg fat percentage (left) 0.5 1.9 4.8 1.1 -0.1 -0.9 2.2 -0.2 -0.0 -2.1 2.1
Arm fat-free mass (left) 0.3 1.7 3.7 1.9 0.9 -0.1 1.6 0.8 -1.6 -1.8 0.5
Number of operations (self-reported) 0.4 0.7 4.8 -0.2 0.5 -0.1 0.2 0.3 -2.2 -0.3 -0.2
Average weekly beer plus cider intake 1.1 1.6 5.1 0.7 1.2 -1.1 -0.5 2.3 0.5 1.8 0.9
Irritability 0.6 1.0 3.3 -1.3 -0.9 -0.6 -1.3 -0.4 1.8 -0.3 0.2
Risk taking 0.8 1.2 3.9 0.1 1.3 -0.3 2.0 1.9 -0.4 -0.4 -0.3
Ever had prostate specific antigen (PSA) test 0.7 0.8 2.6 0.6 -0.5 -0.0 -1.1 -0.4 -0.3 -1.3 -1.6
Fractured/broken bones in last 5 years 2.2 2.8 6.8 1.5 2.6 0.7 1.6 2.4 -1.0 -0.1 1.9
Age started oral contraceptive pill 0.4 0.4 1.8 -0.5 -0.0 0.5 -0.4 0.6 0.7 1.4 0.4
Diastolic blood pressure, automated reading 1.7 5.3 17.7 1.3 2.8 0.5 1.9 2.1 -4.2 -2.7 -0.2
Ever depressed for a whole week 0.2 0.3 1.0 -1.0 -0.0 -0.7 -0.8 0.1 0.2 -0.3 0.1
Unable to work because of sickness or disability 1.2 1.6 4.9 2.2 1.2 -0.9 0.5 1.8 -1.4 0.5 -0.0
Commuting to job workplace: Cycle 1.1 1.3 5.9 -2.4 -1.2 1.0 -0.5 -0.1 0.1 1.3 0.7
Myopia 0.7 1.0 2.7 -1.1 -1.6 -0.9 -0.6 -1.6 0.2 0.3 -0.2
Vascular/heart problems diagnosed by doctor 0.4 1.2 4.6 0.2 -0.9 0.7 -1.3 -1.1 2.1 -0.6 -0.5
Cholesterol lowering medication 0.5 0.7 2.5 -0.8 -0.6 1.2 1.6 0.3 -0.3 0.8 0.0
Medication: Omeprazole (e.g. Zanprol) 1.4 1.7 6.2 -1.0 -1.7 0.4 0.3 -2.5 1.2 0.7 -1.0
Pain experienced in last month 1.1 1.9 5.6 -1.6 -1.1 1.3 0.2 -2.4 1.2 -1.5 -0.8
Supplements: Calcium 0.5 0.5 1.8 1.3 -0.0 -0.2 -0.8 -0.2 1.1 0.7 -0.0
Basal cell carcinoma (self-reported) 0.9 1.1 4.8 -2.2 -1.6 0.8 0.3 -0.0 0.3 0.0 -0.5
Heart attack/myocardial infarction (self-reported) 0.7 0.9 3.5 -0.7 0.6 -1.9 0.2 0.3 -1.4 0.8 0.0
Deep venous thrombosis (DVT) (self-reported) 1.1 1.4 3.3 0.8 1.1 -1.8 -1.3 0.3 1.8 0.7 0.8
Heart disease (siblings) 0.3 0.3 1.2 0.5 0.1 0.6 -0.2 -0.8 -1.1 -0.5 0.2
Alcohol drinker status: Previous 1.7 1.9 6.5 -0.1 1.7 -2.5 -0.5 1.4 0.2 -0.2 -1.9
Pack years of smoking 0.3 0.5 1.4 0.4 -0.1 -1.2 -0.2 0.6 -1.1 0.5 0.5
Impedance of whole body 0.3 1.4 4.0 -1.7 -0.9 -0.5 -1.0 -1.0 2.0 1.0 -0.2
Leg fat mass (left) 0.6 2.3 7.0 1.3 0.1 -0.9 2.6 -0.1 -0.6 -1.9 2.2
Arm predicted mass (left) 0.3 1.4 3.6 1.9 0.6 0.1 1.6 0.6 -1.4 -1.6 0.5