[Hub]/) : Traits : Hayfever, allergic rhinitis or eczema :

chr3:120,799,666-122,356,172

Best TWAS P=2.54e-12 · Best GWAS P=2.17e-12 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SLC15A2 0.07 0.08 lasso 6 0.08 1.7e-09 5.2 -5.3 9.8e-08 0.53 0.98 0.02 FALSE
2 GTEx Brain Cerebellar Hemisphere SLC15A2 0.17 0.03 lasso 15 0.02 9.7e-02 -6.8 -7.0 2.5e-12 0.99 0.04 0.86 TRUE
3 GTEx Brain Cerebellum SLC15A2 0.33 0.47 lasso 18 0.44 1.8e-14 -6.9 -6.9 5.3e-12 1.00 0.03 0.97 FALSE
4 GTEx Breast Mammary Tissue IQCB1 0.36 0.22 enet 23 0.33 2.3e-17 -4.9 -5.3 1.4e-07 0.47 1.00 0.00 FALSE
5 GTEx Esophagus Muscularis SLC15A2 0.12 0.01 enet 19 0.04 2.7e-03 -6.3 -6.3 2.9e-10 0.68 0.06 0.87 FALSE
6 GTEx Heart Atrial Appendage SLC15A2 0.23 0.25 lasso 14 0.24 2.3e-11 -7.0 -6.8 8.4e-12 1.00 0.03 0.97 FALSE
7 GTEx Heart Left Ventricle SLC15A2 0.16 0.19 lasso 6 0.20 8.6e-11 -6.9 -6.8 1.2e-11 0.99 0.03 0.97 FALSE
8 GTEx Liver EAF2 0.16 0.06 enet 32 0.07 5.4e-03 -6.3 -5.9 3.0e-09 0.66 0.07 0.51 FALSE
9 GTEx Muscle Skeletal EAF2 0.05 0.04 lasso 6 0.02 1.5e-03 -5.3 -5.6 2.2e-08 0.61 0.07 0.68 FALSE
10 GTEx Muscle Skeletal SLC15A2 0.11 0.05 enet 43 0.07 8.4e-08 -7.0 -5.3 1.3e-07 0.83 0.03 0.97 FALSE
11 GTEx Nerve Tibial SLC15A2 0.08 0.10 lasso 8 0.07 8.0e-06 -6.9 -6.5 7.2e-11 0.99 0.03 0.97 FALSE
12 GTEx Spleen IQCB1 0.29 0.08 enet 18 0.12 6.9e-04 -4.9 -5.1 3.0e-07 0.43 0.08 0.20 FALSE
13 GTEx Whole Blood IQCB1 0.14 0.04 enet 36 0.07 2.6e-07 5.1 -5.4 6.5e-08 0.53 0.96 0.03 FALSE
14 The Cancer Genome Atlas Brain Lower Grade Glioma EAF2 0.05 0.01 blup 70 0.04 3.3e-05 -7.0 -5.6 2.3e-08 0.78 0.03 0.96 FALSE
15 The Cancer Genome Atlas Thyroid Carcinoma ILDR1 0.06 0.00 blup 48 0.02 3.5e-03 5.0 5.7 1.2e-08 -0.62 0.01 0.54 FALSE
16 The Cancer Genome Atlas Thyroid Carcinoma SLC15A2 0.06 0.04 blup 73 0.05 8.0e-06 4.9 6.8 1.3e-11 -0.80 0.10 0.88 FALSE