Hub : Genes

SLC15A2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0740 0.0240 3.8e-07 0.078 0.069 0.070 0.071 0.075 9.4e-10 7.6e-09 6.7e-09 5.8e-09 1.7e-09
2 GTEx Artery Coronary 0.1320 0.0540 4.0e-03 -0.009 NA 0.003 NA -0.009 9.3e-01 NA 2.5e-01 NA 8.8e-01
3 GTEx Artery Tibial 0.2264 0.0540 3.8e-10 0.144 NA 0.154 NA 0.020 2.4e-11 NA 4.4e-12 NA 1.0e-02
4 GTEx Brain Cerebellar Hemisphere 0.1740 0.0820 4.5e-03 0.035 NA -0.011 NA 0.020 4.5e-02 NA 7.8e-01 NA 9.7e-02
5 GTEx Brain Cerebellum 0.3280 0.0660 8.2e-11 0.468 NA 0.394 NA 0.441 1.4e-15 NA 1.0e-12 NA 1.7e-14
6 GTEx Esophagus Muscularis 0.1230 0.0480 2.4e-04 0.011 NA 0.037 NA 0.036 6.7e-02 NA 2.7e-03 NA 2.9e-03
7 GTEx Heart Atrial Appendage 0.2350 0.0590 8.3e-09 0.251 NA 0.223 NA 0.245 1.2e-11 NA 2.2e-10 NA 2.3e-11
8 GTEx Heart Left Ventricle 0.1628 0.0425 3.9e-08 0.194 NA 0.177 NA 0.198 1.4e-10 NA 1.0e-09 NA 8.6e-11
9 GTEx Muscle Skeletal 0.1088 0.0354 2.5e-07 0.051 NA 0.075 NA 0.070 8.9e-06 NA 8.4e-08 NA 2.0e-07
10 GTEx Nerve Tibial 0.0830 0.0318 1.9e-04 0.100 NA 0.052 NA 0.072 1.4e-07 NA 1.4e-04 NA 8.0e-06
11 GTEx Spleen 0.4420 0.0950 7.9e-06 0.290 NA 0.293 NA 0.250 3.7e-08 NA 3.1e-08 NA 4.2e-07
12 METSIM Adipose 0.0422 0.0170 1.3e-03 0.004 0.010 0.014 0.011 0.011 6.4e-02 9.3e-03 3.3e-03 8.4e-03 8.3e-03
13 YFS Blood 0.0576 0.0167 1.6e-08 0.039 0.041 0.048 0.052 0.043 8.5e-13 1.9e-13 1.8e-15 1.8e-16 5.2e-14
14 TCGA Thyroid Carcinoma 0.0550 0.0320 2.5e-05 0.045 0.052 0.014 NA 0.050 3.2e-05 8.0e-06 1.4e-02 NA 1.3e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 0.4 0.6 2.1 0.1 0.7 1.2 0.3 0.3 -0.3 0.1 0.3 1.4 0.2 0.8 1.4 -1.4 -0.1
Bipolar Disorder or Schizophrenia 0.6 1.5 3.1 -1.0 -0.4 -0.3 -1.5 -1.4 -1.3 -1.4 -1.5 0.4 -1.4 0.5 1.8 -1.1 1.6
Depressed Affect (Nagel 2018) 0.9 1.9 4.6 -0.3 -1.0 -0.5 -2.0 -2.1 -0.3 -2.0 -2.1 -1.7 -2.1 -0.7 -0.2 0.1 1.1
Depression (Nagel 2018) 0.3 0.4 2.5 0.5 -0.9 -1.6 -0.1 -0.1 0.7 0.1 0.1 -0.4 -0.1 -0.1 -0.9 -0.4 -0.5
Intelligence (Savage-Jansen 2018) 0.2 0.6 3.8 -0.8 -0.5 -1.9 -0.2 -0.0 -0.8 0.1 0.1 -0.7 0.1 1.2 0.3 -1.1 0.5
Neuroticism (Nagel 2018) 1.8 4.2 8.2 -0.3 -2.0 -1.9 -2.8 -2.8 -0.5 -2.6 -2.8 -2.3 -2.9 -1.6 -1.0 1.0 1.4
Schizophrenia (2018) 1.2 2.5 4.6 -1.3 -1.0 -1.5 -2.1 -2.1 -1.5 -1.9 -2.1 -0.7 -2.0 -0.0 1.1 -0.4 2.2
Schizophrenia vs Biploar Disorder 2.6 3.5 7.0 -1.4 -0.8 -1.2 -2.4 -2.4 -0.9 -2.4 -2.6 -2.1 -2.4 -0.9 -0.0 2.0 2.1
Worry (Nagel 2018) 0.7 1.5 7.0 -0.0 -1.7 -2.7 -1.3 -1.2 0.3 -1.2 -1.2 -1.2 -1.3 -1.4 -0.4 0.2 0.7
Alzheimer’s Disease (in mother) 0.8 1.0 2.0 -0.5 -0.6 -1.0 -1.4 -1.3 -0.6 -1.3 -1.2 -1.2 -1.4 -0.2 0.8 0.5 0.7
Alzheimer’s Disease (in father) 1.8 2.0 2.9 -1.6 -1.4 -1.0 -1.7 -1.6 -1.7 -1.5 -1.6 -0.4 -1.6 0.6 1.6 -0.2 1.7
Alzheimer’s Disease (including proxy) 0.8 1.2 2.5 -0.6 -1.0 -0.6 -1.6 -1.5 -0.9 -1.4 -1.4 -0.7 -1.5 0.2 1.3 -0.0 0.9
Crohns Disease (2017) 1.8 3.9 10.2 3.2 0.9 1.7 1.8 1.9 2.8 1.9 1.8 1.9 1.5 -0.0 -0.1 -2.0 -3.1
Irritable Bowel Disease (IBD) 0.5 1.2 4.9 2.2 0.0 1.5 0.5 0.6 1.6 0.5 0.5 0.4 0.4 -0.8 -0.8 -1.0 -1.9
Ulcerative Colitis (UC) 0.2 0.5 1.0 0.2 -0.3 0.7 -0.9 -0.9 0.0 -0.9 -0.9 -0.8 -0.8 -1.0 -0.6 0.0 -0.0
Major Depression (MDD) 0.5 0.6 2.3 -0.7 -1.5 -1.4 -0.4 -0.4 -1.0 -0.3 -0.2 -0.5 -0.2 0.5 -0.5 -0.8 0.6
Reaction Time 0.8 1.5 6.8 -2.6 0.3 -1.5 -0.9 -0.9 -1.0 -1.0 -0.5 -0.6 -0.8 -0.2 -0.7 1.6 1.9
Verbal and Numeric Reasoning (VNR) 0.3 0.8 5.0 0.4 -0.3 -1.0 -0.1 0.2 -0.3 0.5 0.4 -0.1 0.3 1.3 1.3 -2.2 -0.6
Breast Cancer 0.7 1.6 3.9 1.2 0.7 1.8 0.9 1.2 0.4 1.3 1.0 1.6 1.4 2.0 0.4 -1.4 -1.2
Ovarian Cancer 0.3 0.4 0.9 0.4 0.7 -0.5 0.8 0.6 0.6 0.7 0.7 -0.1 0.7 -0.8 -0.9 0.0 -0.7
Prostate Cancer 0.4 0.6 3.1 0.7 0.4 0.9 0.5 0.6 0.2 0.5 0.3 1.8 0.6 1.1 0.4 -1.0 -0.6
Age at First Birth 0.2 0.3 2.0 0.2 -0.7 1.4 -0.2 -0.2 0.3 -0.2 -0.2 0.9 -0.3 -0.5 0.6 -0.4 0.2
Bipolar Disorder (2011) 1.3 1.3 7.8 -0.3 0.4 0.7 -0.7 -0.6 -0.6 -0.6 -0.6 0.8 -0.7 0.8 2.8 -2.4 0.6
Body Mass Index (BMI) (2010) 0.2 0.3 0.9 -0.8 0.9 0.3 -0.0 -0.1 0.5 -0.0 0.2 0.7 -0.0 0.9 0.4 -0.5 0.7
Coronary Artery Disease (CAD) 1.0 1.2 2.4 -0.8 0.1 -0.9 -1.2 -1.3 -1.1 -1.1 -0.9 -1.6 -1.2 -1.3 -1.4 0.9 1.2
Crohns Disease (2012) 1.0 1.6 6.3 2.5 0.9 0.9 0.9 1.0 1.9 1.0 1.0 0.7 0.8 0.0 -0.8 -0.9 -2.2
Mean Putamen Volume 0.4 0.4 2.0 0.1 1.4 0.9 0.1 0.2 -0.4 0.3 0.5 0.8 0.3 0.7 0.7 -0.9 -0.3
Fasting Glucose 0.2 0.3 1.3 0.1 -0.2 -0.3 -0.3 -0.3 -1.0 -0.7 -0.6 -1.1 -0.3 -0.1 0.3 -0.1 0.4
HbA1C 1.0 1.1 3.3 1.8 -1.1 0.4 0.6 0.8 1.2 0.8 0.5 1.0 0.6 0.3 1.1 -1.5 -1.4
HDL Cholesterol 0.3 0.6 2.9 0.5 -0.3 1.1 -0.1 0.1 -0.3 0.2 -0.1 0.4 0.0 1.0 1.3 -1.7 -0.6
LDL Cholesterol 0.7 1.2 6.6 -1.8 -1.1 -0.1 -0.8 -0.6 -2.6 -0.6 -0.8 0.1 -0.3 0.7 1.1 -0.1 1.2
Lupus 5.9 8.9 17.9 -1.3 -2.0 -2.8 -4.1 -4.1 -1.4 -4.0 -4.0 -3.6 -4.2 -1.7 -0.3 1.0 2.7
Neuroticism (2016) 1.1 1.6 6.8 1.1 -2.6 -0.4 -0.3 -0.4 -0.4 -0.4 -0.7 -1.3 -0.2 -1.5 -2.5 1.7 -0.8
Primary Biliary Cirrhosis 1.7 2.5 6.0 1.2 0.2 0.5 -2.2 -2.3 0.3 -2.2 -2.3 -1.9 -2.5 -1.5 0.7 0.1 0.4
Rheumatoid Arthritis 2.4 3.3 9.5 -0.2 -2.0 -0.8 -2.4 -2.2 -3.1 -2.0 -2.4 -1.2 -2.1 -0.2 1.2 -1.6 1.0
Schizophrenia (2014) 1.2 2.6 5.5 -1.1 -1.0 -0.9 -2.3 -2.3 -1.1 -2.2 -2.3 -0.8 -2.4 -0.0 1.2 -0.2 2.0
Triglycerides 0.6 1.0 6.4 -1.4 -0.1 -0.3 -0.6 -0.5 -1.3 -0.5 -0.4 -0.1 -0.4 2.5 0.9 -0.2 1.4
Type 2 Diabetes (T2D) (2012) 0.4 0.4 1.3 -0.4 1.1 -0.1 0.8 0.8 -0.9 0.9 0.6 -0.1 0.7 0.6 0.6 0.1 -0.1
Ulcerative Colitis 0.7 1.1 2.5 -0.4 -1.6 0.3 -1.1 -1.3 -0.3 -1.2 -1.3 -0.6 -1.2 -1.5 -0.9 0.7 0.6
Blood Eosinophil Count 0.3 2.3 9.5 0.1 -0.9 1.2 1.7 1.4 -0.4 1.2 1.5 2.3 2.1 -0.3 -3.1 0.7 -1.1
Blood Platelet Count 2.3 26.3 48.6 4.5 1.4 2.4 7.0 6.8 6.8 6.4 6.9 4.3 6.9 0.0 -2.6 0.1 -6.0
Blood Red Count 1.0 10.0 18.8 -2.9 0.2 -2.0 -4.1 -4.3 -2.4 -4.2 -4.0 -3.4 -4.3 -0.2 -0.7 2.5 4.0
Blood White Count 0.2 1.7 3.6 -0.1 1.6 1.4 1.4 1.6 0.3 1.5 1.5 1.9 1.4 1.7 0.9 0.1 -0.8
Heel T-Score 1.2 9.2 18.7 2.5 0.6 1.8 4.3 4.0 2.6 3.7 4.0 2.2 4.1 0.6 -3.5 0.9 -3.5
BMI 0.6 3.2 16.6 -1.3 3.2 1.0 0.5 0.8 -0.1 0.8 1.0 1.0 0.9 4.1 2.9 -1.7 0.6
Height 0.2 4.4 24.2 -4.9 1.2 -2.2 -0.8 -0.7 -0.7 -0.5 -0.1 -0.9 -0.5 3.1 1.3 -0.9 4.0
Waist Hip Ratio (WHR) 0.2 0.7 4.0 -0.9 0.4 -0.4 -0.8 -0.8 -2.0 -0.9 -1.0 -0.8 -0.7 -0.3 0.5 0.4 0.8
Systolic Blood Pressure 2.8 13.9 31.5 3.8 1.4 4.1 4.7 4.5 4.2 4.3 4.0 5.6 4.5 -0.6 0.1 -0.3 -3.8
Smoking Status 0.3 0.7 2.9 -1.7 1.6 0.3 0.2 0.4 -0.8 0.4 0.5 0.6 0.3 1.2 0.2 0.6 0.8
Allergy or Eczema 15.2 40.0 70.0 -5.7 -4.3 -4.3 -8.4 -8.2 -7.7 -8.1 -8.1 -6.6 -7.8 -0.6 0.9 1.0 7.5
Cardiovascular Disease 1.5 5.0 16.0 0.3 0.3 2.8 2.9 2.8 1.1 2.7 2.7 4.0 3.0 0.1 -1.6 1.2 -1.2
Hypothyroidism (self reported) 4.5 10.4 20.6 -4.1 -2.2 -2.4 -4.3 -4.1 -3.6 -4.0 -4.0 -1.9 -3.4 -0.9 -0.8 0.9 4.5
Respiratory disease 4.1 9.1 17.5 -2.9 -1.2 -2.6 -4.2 -4.0 -3.2 -3.7 -3.7 -2.7 -3.8 1.2 1.1 -1.2 3.8
Type 2 Diabetes (T2D) (2018) 0.6 1.1 2.6 0.4 -0.4 0.9 1.6 1.6 -0.2 1.5 1.6 0.6 1.5 -0.3 -0.9 0.4 -1.1
Lung FEV1/FVC ratio 1.1 5.5 10.8 1.4 2.7 3.3 3.1 2.8 2.3 2.6 2.6 2.8 2.8 -0.4 -0.3 -0.1 -2.3
Lung FVC 0.3 1.4 3.7 -0.6 1.9 0.9 1.7 1.5 -0.4 1.5 1.3 1.5 1.4 -0.5 0.2 0.6 -0.6
Neuroticism 0.8 1.9 6.8 0.7 -2.6 -1.7 -1.5 -1.5 0.2 -1.5 -1.5 -1.3 -1.6 -1.2 -1.1 0.1 0.2
Chronotype (morning person) 0.5 1.2 4.6 -1.0 -2.1 -1.8 0.0 0.0 -0.4 -0.2 -0.0 -0.8 -0.0 -1.6 -1.5 1.3 0.5
Hair Pigment 0.0 0.9 4.2 2.1 -0.0 1.5 0.0 -0.1 0.9 0.2 0.0 1.0 -0.1 -1.5 -0.0 -0.0 -1.4
Tanning 0.0 0.4 0.8 -0.5 -0.7 -0.9 -0.7 -0.6 -0.8 -0.6 -0.5 -0.8 -0.4 -0.3 -0.8 0.8 0.2
Hand grip strength (left) 0.3 0.9 3.8 -0.1 0.1 -0.4 -0.1 -0.4 0.4 -0.6 -0.4 -1.4 -0.4 -1.6 -2.0 1.5 0.3
Number of treatments/medications taken 0.4 0.8 2.4 0.4 0.1 0.6 0.8 1.1 -0.2 1.2 1.1 1.5 1.3 1.0 -0.2 0.0 -1.0
Average weekly spirits intake 0.5 0.6 2.7 1.6 -0.6 -0.1 -0.4 -0.5 -0.4 -0.4 -0.5 -0.7 -0.4 -0.7 -0.8 -1.4 -0.9
Sensitivity / hurt feelings 2.2 3.8 6.2 0.3 -2.5 -1.4 -2.0 -2.2 -0.8 -2.3 -2.2 -1.9 -2.2 -2.3 -2.4 2.2 0.6
Frequency of depressed mood in last 2 weeks 0.6 0.8 3.4 0.6 -1.8 -1.4 -0.3 -0.3 1.1 -0.2 0.0 -0.5 -0.3 -0.8 -1.8 -0.2 -0.5
Hearing difficulty/problems: Yes 2.5 3.8 16.0 -4.0 -0.4 -1.7 -1.8 -1.8 -1.8 -1.7 -1.7 -0.4 -1.7 0.4 0.7 1.0 3.8
Relative age of first facial hair 0.1 0.3 1.2 1.1 -0.1 0.8 0.3 0.3 0.2 0.2 0.0 -0.4 0.4 -0.9 0.2 -0.6 -0.8
Other serious medical condition/disability diagnosed by doctor 0.2 0.3 1.5 -0.9 0.0 0.1 -0.4 -0.4 -0.3 -0.4 -0.4 0.1 -0.3 1.2 -0.4 0.5 1.0
Ever used hormone-replacement therapy (HRT) 3.7 4.7 8.3 2.0 2.7 0.3 2.8 2.8 1.7 2.9 2.8 1.9 2.6 1.5 -0.3 -0.1 -2.6
Ever had hysterectomy (womb removed) 0.9 1.0 3.6 -0.6 1.9 0.4 0.6 0.8 -0.2 1.0 0.8 0.8 0.7 1.6 1.2 -1.4 -0.1
Systolic blood pressure, automated reading 4.2 12.1 19.0 4.0 2.1 3.2 4.4 4.3 3.9 4.1 3.8 4.2 4.2 0.5 0.8 -0.5 -4.3
Eye problems/disorders: Diabetes related eye disease 1.9 2.1 5.1 0.4 0.1 0.5 2.2 2.1 0.4 2.1 2.2 1.3 2.2 1.1 -0.0 -0.4 -1.3
Angina 3.0 3.9 7.1 1.9 2.3 2.7 2.2 2.2 1.4 2.2 2.3 2.2 2.1 0.8 0.8 -1.2 -2.4
Medication for hormone replacement therapy 3.4 3.8 7.2 1.8 1.6 1.0 2.7 2.5 1.9 2.5 2.6 2.3 2.4 0.4 -0.3 0.2 -2.2
Vitamin and mineral supplements 0.6 0.8 1.8 -0.0 -0.6 0.8 -0.8 -1.1 -0.8 -1.1 -1.3 -0.7 -1.1 -0.8 -0.3 1.2 0.7
Supplements: Zinc 1.0 1.1 2.7 0.9 0.2 -0.4 1.2 1.4 1.1 1.4 1.6 0.8 1.3 0.5 0.2 -1.1 -1.3
Medication: Co-codamol 0.6 0.7 1.7 0.6 -0.3 0.2 0.9 1.0 -0.4 1.0 0.9 1.1 1.1 -0.1 -0.6 -0.9 -1.3
Medication: Metformin 0.5 0.7 2.0 -0.1 -0.7 0.3 1.3 1.2 -0.5 1.2 1.4 0.2 1.2 -0.3 -0.1 0.5 -0.7
Diabetes (father) 0.6 0.7 2.3 0.4 1.0 0.6 0.8 0.7 1.5 0.9 1.0 1.2 0.7 0.9 -0.1 -0.3 -0.4
Diabetes (mother) 0.5 0.6 2.3 0.4 0.5 0.5 0.7 0.7 1.4 0.9 0.9 0.2 0.7 1.5 0.8 -0.1 -0.4
Severe depression (siblings) 0.8 0.9 2.0 -1.0 -0.6 -1.1 -1.2 -1.3 -0.9 -1.1 -1.1 -0.8 -1.0 -0.7 -0.0 -0.2 1.4
Pack years adult smoking proportion 1.4 2.1 5.2 1.4 2.3 2.2 1.4 1.4 1.6 1.4 1.4 0.8 1.1 0.7 1.5 -0.8 -1.3
Impedance of leg (right) 0.2 0.9 4.1 0.6 0.7 0.5 0.7 0.6 0.7 0.5 0.3 0.5 0.5 -1.9 -1.2 2.0 -0.9
Leg fat-free mass (left) 0.5 2.5 12.9 -2.4 0.9 -0.3 -0.9 -0.7 -0.6 -0.6 -0.3 -0.7 -0.6 3.6 1.9 -1.9 2.3
Trunk fat percentage 0.8 3.1 14.3 -0.7 3.8 0.8 1.0 1.3 0.5 1.3 1.4 1.1 1.2 3.7 2.0 -1.2 -0.1
Hand grip strength (right) 0.2 0.5 2.7 0.2 0.3 0.0 0.3 0.1 0.9 0.0 0.3 -0.9 0.1 -1.2 -1.6 0.6 -0.1
Townsend deprivation index at recruitment 1.7 2.4 3.9 1.0 1.2 1.5 2.0 1.8 2.0 1.7 1.8 1.6 1.9 0.5 -1.6 1.1 -1.3
Current tobacco smoking 0.4 0.7 1.6 -0.8 0.8 0.2 -1.1 -0.9 -0.8 -0.9 -0.9 -1.0 -1.0 0.5 1.3 -0.3 0.9
Average weekly fortified wine intake 1.2 1.4 5.9 0.2 2.4 0.1 1.3 1.2 2.0 1.2 1.5 0.5 1.2 0.7 0.1 -0.3 -0.5
Maternal smoking around birth 0.1 0.2 1.5 -0.2 0.9 0.4 0.4 0.2 0.1 0.2 0.2 -0.1 0.1 -0.0 1.2 -0.0 -0.0
Fed-up feelings 1.2 2.2 4.7 -0.7 -1.3 0.1 -2.0 -2.1 -0.4 -2.1 -2.2 -1.1 -2.2 -1.8 -0.3 0.7 1.3
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.4 1.5 0.8 -0.1 -0.3 0.4 0.4 1.2 0.5 0.6 0.5 0.3 0.1 -0.7 -0.4 -1.0
Relative age voice broke 0.5 0.8 2.7 1.6 -0.4 0.4 0.4 0.6 1.5 0.7 0.6 0.5 0.6 -0.2 0.2 -1.1 -1.6
Taking other prescription medications 0.5 0.7 1.9 -0.5 -1.0 -0.8 -1.4 -1.0 -0.8 -1.0 -1.0 -0.3 -0.8 -0.1 -0.9 0.7 0.6
Age when periods started (menarche) 0.3 0.8 4.0 1.0 -0.8 -0.2 0.2 0.0 -0.0 -0.1 -0.1 0.2 -0.1 -2.0 -1.6 1.3 -0.8
Bilateral oophorectomy (both ovaries removed) 0.9 1.0 2.4 0.9 1.2 0.8 0.9 0.9 0.9 1.0 1.2 1.1 0.8 1.6 0.5 -1.0 -1.0
Heel bone mineral density (BMD) T-score, automated (left) 1.1 2.6 5.4 1.6 -0.6 0.4 2.3 2.2 1.4 2.0 2.2 0.9 2.1 0.5 -1.2 0.6 -2.1
Tinnitus: Yes, but not now, but have in the past 0.8 0.8 2.5 -0.0 0.0 -1.3 -1.2 -1.2 -0.4 -1.1 -1.1 -1.6 -1.1 -0.2 0.7 -0.1 0.7
Qualifications: CSEs or equivalent 0.5 0.7 1.4 -0.1 -0.7 -0.1 0.9 0.8 1.1 0.7 0.8 1.1 0.7 -1.2 -1.2 0.8 -0.3
Serious illness, injury or assault to yourself 0.5 0.6 3.5 -0.8 1.3 -1.1 -0.4 -0.3 -0.3 -0.2 -0.1 -0.6 -0.1 1.9 0.0 -0.4 0.7
High blood pressure 0.9 2.6 7.6 1.2 0.5 2.4 1.8 1.8 1.2 1.8 1.7 2.8 1.8 -0.1 -0.8 1.4 -1.5
Hayfever, allergic rhinitis or eczema 13.4 29.0 49.0 -5.3 -3.9 -3.9 -7.0 -6.9 -6.3 -6.8 -6.8 -5.3 -6.5 -0.4 0.7 1.0 6.8
Multivitamins +/- minerals 2.8 3.5 7.6 1.0 2.0 0.7 2.3 2.4 2.4 2.3 2.8 1.7 2.4 0.8 0.3 -1.1 -1.9
Stomach or abdominal pain in last month 0.5 0.7 4.7 -0.2 -0.0 -0.1 -0.7 -0.5 -0.1 -0.2 -0.4 0.3 -0.5 2.2 1.0 -1.4 0.5
Supplements: Glucosamine 0.2 0.3 0.6 0.2 -0.2 -0.1 -0.8 -0.7 -0.7 -0.7 -0.7 -0.4 -0.7 -0.1 0.7 -0.7 0.0
Diverticular disease/diverticulitis (self-reported) 2.0 2.4 4.2 -1.6 -1.4 -1.8 -2.0 -2.0 -0.4 -1.9 -1.7 -1.6 -1.7 0.1 -0.7 0.8 2.0
Medication: Atenolol 0.1 0.2 0.5 0.1 0.5 -0.2 0.4 0.5 -0.0 0.6 0.7 0.3 0.5 -0.3 -0.3 -0.1 -0.2
Medication: Levothyroxine sodium 6.2 10.5 20.8 -3.5 -1.0 -1.7 -4.6 -4.3 -3.3 -4.2 -4.5 -2.3 -3.9 -0.9 1.0 1.0 4.4
Sitting height 0.2 1.7 8.6 -2.9 -1.1 -1.8 -0.1 -0.1 0.1 -0.1 0.4 -0.7 0.1 2.3 -0.5 -0.3 2.2
Chronic bronchitis/emphysema (father) 3.5 4.1 12.6 -3.5 -0.2 -2.0 -2.0 -1.9 -2.3 -1.9 -1.7 -2.0 -1.8 0.7 0.5 1.4 3.4
High blood pressure (mother) 0.2 0.2 0.9 -0.9 -0.2 -0.9 -0.2 -0.2 -0.6 -0.1 -0.2 0.3 -0.2 -0.2 -0.1 0.4 0.9
Body mass index (BMI) 0.6 2.5 14.6 -0.8 2.6 1.2 0.3 0.6 -0.0 0.7 0.8 0.9 0.7 3.8 2.6 -1.6 0.4
Impedance of leg (left) 0.2 0.9 2.2 0.8 0.7 0.1 1.0 1.0 1.0 0.8 0.7 0.6 0.8 -1.3 -1.1 1.5 -1.2
Leg predicted mass (left) 0.5 2.5 13.0 -2.4 0.9 -0.3 -0.8 -0.7 -0.5 -0.6 -0.3 -0.7 -0.5 3.6 1.9 -1.9 2.3
Trunk fat mass 0.8 3.4 17.1 -1.1 3.5 0.8 0.7 1.0 0.4 1.1 1.3 0.9 1.1 4.1 2.4 -1.7 0.4
Waist circumference 0.8 2.9 14.4 -1.6 3.1 0.5 0.4 0.7 -0.5 0.7 0.9 0.6 0.8 3.8 2.7 -1.5 0.7
Number of incorrect matches in round 0.4 0.7 1.3 1.0 -0.6 0.4 0.9 0.9 0.8 0.8 0.9 0.5 0.8 -1.1 -0.8 0.7 -1.0
Past tobacco smoking 0.6 1.1 4.5 0.5 -2.1 0.3 -0.9 -0.9 -0.6 -1.1 -1.3 -0.9 -0.9 -2.1 0.4 -0.2 0.3
Alcohol usually taken with meals 1.3 2.1 4.8 -0.2 -2.0 -0.8 -1.8 -1.8 0.9 -1.7 -1.5 -1.1 -1.9 -0.9 -2.2 1.1 1.0
Nervous feelings 0.9 1.6 10.3 0.1 -1.7 -2.2 -0.6 -0.6 -0.2 -0.6 -0.3 -0.6 -0.6 -3.2 -1.3 1.1 -0.0
Frequency of tenseness / restlessness in last 2 weeks 0.5 0.8 3.7 -0.5 -1.9 -0.6 -0.9 -0.9 0.1 -0.7 -0.6 0.2 -0.8 0.7 -0.2 -1.6 0.5
Hearing difficulty/problems with background noise 2.4 3.9 16.6 -4.1 -0.5 -2.5 -1.4 -1.4 -2.3 -1.4 -1.3 -0.9 -1.3 -0.8 -0.7 1.9 3.3
Hair/balding pattern: Pattern 2 0.2 0.2 0.9 0.8 0.3 0.2 0.2 0.1 0.3 0.2 -0.0 0.1 0.0 0.9 0.7 -0.9 -0.4
Had menopause 0.4 0.5 2.2 1.1 -0.2 0.6 -0.5 -0.4 0.1 -0.4 -0.6 -0.1 -0.5 -1.1 -0.6 1.5 -0.7
Had other major operations 0.1 0.2 1.1 -0.5 0.7 0.3 -0.0 0.0 0.1 -0.1 -0.1 0.6 0.0 0.1 -0.2 1.1 0.3
Forced vital capacity (FVC) 0.1 0.3 1.7 -1.3 0.9 -0.2 0.3 0.0 0.3 -0.1 0.1 -0.0 0.0 -0.4 -0.3 0.2 1.0
Heel bone mineral density (BMD) T-score, automated (right) 1.4 3.2 6.4 2.1 -0.9 1.0 2.3 2.3 1.7 2.2 2.4 1.3 2.3 0.9 -1.0 -0.2 -2.5
Ever unenthusiastic/disinterested for a whole week 3.8 4.6 7.7 -2.6 -0.7 -0.7 -2.6 -2.5 -2.3 -2.1 -2.1 -2.2 -2.4 2.7 1.7 -0.9 2.8
Qualifications: None of the above 1.0 2.1 3.8 1.7 1.6 1.8 1.8 1.8 0.8 1.6 1.7 1.4 1.7 -0.1 -0.5 -0.5 -2.0
Financial difficulties in last 2 years 0.8 1.1 2.4 1.6 0.7 0.9 1.3 1.1 1.0 1.2 1.2 0.5 1.1 -0.9 -0.9 0.3 -1.5
Mouth/teeth dental problems 1.9 2.9 4.7 1.6 0.4 2.0 2.1 2.0 2.0 2.2 2.2 2.0 2.1 -0.1 0.0 -0.9 -1.8
Heart attack 0.3 0.4 1.3 0.3 0.8 -0.6 -0.4 -0.3 -1.0 -0.4 -0.3 -1.2 -0.3 0.5 -1.1 0.6 -0.0
Allergy 9.8 22.5 41.5 5.4 2.2 4.5 6.1 5.9 5.0 5.8 5.5 5.0 5.6 -0.8 -1.3 -0.1 -6.4
Pain all over the body in last month 0.2 0.3 1.4 0.1 -0.2 -0.7 -0.3 -0.2 0.8 -0.2 -0.2 0.3 -0.1 -0.7 -1.2 -0.3 -0.1
Diabetes (self-reported) 0.4 0.6 1.5 -0.7 -0.4 -0.2 1.1 1.0 -1.2 1.1 1.1 0.5 1.1 -0.1 -0.3 0.5 -0.1
Hayfever/allergic rhinitis (self-reported) 2.8 3.8 9.9 -2.3 -2.4 -1.4 -2.1 -1.9 -3.2 -2.0 -2.0 -1.8 -1.8 -0.2 -0.9 1.4 2.2
Medication: Ramipril 1.4 1.8 3.6 -0.8 0.7 1.6 1.7 1.7 0.8 1.7 1.9 1.6 1.8 1.6 -0.4 0.4 -0.3
Medication: Simvastatin 0.5 0.7 2.6 -0.7 0.4 0.5 0.9 0.9 -1.6 0.9 0.9 1.1 0.9 -0.3 0.9 0.6 0.1
Fluid intelligence score 0.5 1.1 3.3 0.3 -1.0 -1.1 -1.1 -0.8 -0.1 -0.5 -0.6 -0.9 -0.6 1.8 1.7 -1.8 0.0
Illnesses of siblings 0.9 1.3 2.7 -1.1 -1.6 -1.6 -1.2 -1.2 -0.6 -1.2 -0.9 -1.3 -1.0 -0.1 -1.3 0.6 1.3
Neuroticism score 0.9 1.8 5.0 0.1 -2.2 -1.6 -1.5 -1.5 0.3 -1.5 -1.4 -1.3 -1.6 -1.9 -1.0 0.4 0.6
Weight 0.6 3.1 20.8 -1.9 2.5 0.5 0.1 0.4 0.1 0.5 0.8 0.3 0.5 4.6 2.5 -1.8 1.4
Impedance of arm (right) 0.3 1.5 6.2 1.1 0.2 -0.4 1.0 0.8 1.4 0.6 0.6 0.3 0.6 -2.5 -2.3 1.6 -1.1
Arm fat percentage (right) 0.7 2.9 11.5 0.2 3.4 1.4 1.2 1.4 1.0 1.4 1.4 1.4 1.3 3.1 1.8 -1.1 -0.8
Trunk fat-free mass 0.4 2.5 9.2 -2.6 0.2 -0.9 -1.2 -1.1 -1.0 -1.0 -0.6 -1.3 -0.9 3.0 1.5 -1.4 2.5
Hip circumference 0.7 3.1 16.7 -2.6 2.3 0.2 -0.6 -0.4 -0.8 -0.2 0.1 0.0 -0.2 4.1 2.7 -1.5 2.0
Time employed in main current job 0.3 0.3 2.3 -0.0 0.5 0.3 0.3 0.5 1.5 0.4 0.5 0.4 0.4 -0.2 -0.5 -0.3 -0.2
Alcohol intake versus 10 years previously 0.7 1.1 3.9 -1.5 1.5 0.6 -0.5 -0.5 -0.9 -0.8 -1.0 0.0 -0.6 -1.1 0.8 2.0 1.3
Father’s age at death 1.6 2.1 6.1 -1.0 -0.7 -2.5 -1.5 -1.5 -1.4 -1.5 -1.5 -1.8 -1.5 -1.4 -1.1 0.7 1.4
Worrier / anxious feelings 1.0 1.9 3.9 0.4 -1.5 -1.1 -2.0 -2.0 -0.3 -1.9 -1.9 -1.2 -2.0 -1.2 -0.4 0.5 0.6
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.6 3.5 0.3 0.3 0.6 0.2 0.1 1.2 0.3 0.1 1.0 0.2 1.9 0.5 -1.4 -0.1
Falls in the last year 0.7 0.9 2.9 -1.7 1.3 -0.7 -0.9 -0.8 -1.0 -0.6 -0.6 -0.6 -0.6 1.0 -0.3 -0.5 1.6
Hair/balding pattern: Pattern 3 1.0 1.5 3.7 0.7 -0.2 -0.2 1.4 1.5 1.4 1.5 1.6 1.9 1.6 1.6 -0.1 -0.7 -1.0
Number of live births 0.4 0.6 1.6 1.3 -0.2 0.6 0.6 0.6 0.3 0.4 0.3 0.6 0.8 -0.7 -0.9 0.9 -1.3
Forced expiratory volume in 1-second (FEV1) 0.2 0.7 1.8 -0.7 1.3 1.1 1.1 0.9 0.7 0.7 0.8 1.2 0.8 -0.4 0.0 -0.2 0.2
Pulse rate 1.0 1.8 6.7 1.2 1.4 1.3 0.9 1.0 2.6 1.2 1.0 1.2 1.1 0.9 0.5 -2.0 -0.9
Happiness 0.7 0.8 2.0 0.3 -0.9 0.8 -1.1 -1.1 0.1 -1.0 -0.9 -0.5 -1.2 -1.1 -1.4 0.8 0.2
Noisy workplace 0.7 0.8 6.3 0.9 -0.1 2.5 0.7 0.5 1.1 0.3 0.3 1.3 0.4 -0.0 0.1 0.6 -0.8
Qualifications: A levels/AS levels or equivalent 0.5 1.2 3.3 0.3 -0.3 -0.9 -1.8 -1.7 0.7 -1.5 -1.5 -0.4 -1.6 0.0 -1.0 0.2 0.8
Serious illness, injury or assault of a close relative in last 2 years 0.7 0.9 2.3 -0.7 0.1 -0.6 -1.2 -1.1 0.2 -0.8 -0.7 -0.9 -1.0 1.1 0.9 -1.5 1.3
Mouth/teeth dental problems: Dentures 1.3 2.2 4.6 -0.8 0.1 0.4 -2.0 -2.1 -1.9 -2.1 -2.1 -1.4 -2.1 0.2 0.4 0.5 1.4
Asthma 4.0 7.9 14.3 -3.3 -0.8 -3.0 -3.6 -3.4 -3.2 -3.3 -3.1 -3.0 -3.2 0.7 0.9 0.0 3.8
Medication: Ibuprofen (e.g. Nurofen) 1.3 1.7 3.7 0.2 -0.7 1.2 1.8 1.8 0.5 1.7 1.6 1.6 1.9 0.9 0.0 -0.8 -1.2
Medication: Cholesterol lowering 0.6 0.9 5.1 -0.3 -0.5 -0.6 0.8 0.9 -2.3 1.0 0.9 1.1 1.1 0.3 0.9 0.1 -0.4
Depression (self-reported) 0.8 1.0 2.4 -0.4 0.2 0.3 -1.5 -1.4 -0.5 -1.5 -1.5 -0.7 -1.5 0.4 0.3 0.0 0.8
Medication: Lansoprazole 0.2 0.2 0.6 -0.5 0.8 0.7 0.4 0.4 -0.5 0.3 0.5 0.2 0.6 0.5 -0.3 0.4 0.1
Prospective memory result 0.8 0.9 4.9 0.2 1.5 0.8 1.1 0.8 -0.2 0.5 0.4 0.4 0.8 -1.3 -0.6 2.2 -0.4
Lung cancer (father) 0.4 0.5 2.6 0.2 0.4 -0.0 0.1 0.0 0.3 0.1 0.4 -0.2 0.1 1.5 1.3 -1.6 0.1
Illnesses of mother 0.1 0.2 1.2 0.2 0.1 0.7 0.4 0.4 0.0 0.2 0.4 -0.1 0.4 0.3 -1.1 -0.2 -0.3
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.6 1.3 -0.5 1.1 0.9 0.9 0.8 0.8 0.7 0.9 1.1 0.8 0.4 0.6 -0.9 0.0
Pulse wave Arterial Stiffness index 1.0 1.1 2.6 -0.3 1.2 0.6 1.4 1.4 0.8 1.4 1.3 1.6 1.3 1.1 0.5 0.0 -0.0
Impedance of arm (left) 0.2 0.9 4.0 0.9 0.3 -0.3 0.8 0.7 1.4 0.5 0.5 0.2 0.5 -2.0 -1.6 1.0 -0.9
Arm fat mass (right) 0.7 2.9 15.0 -1.0 3.2 1.1 0.6 0.9 0.5 0.9 1.1 0.9 0.9 3.9 2.3 -1.6 0.3
Trunk predicted mass 0.4 2.4 9.5 -2.5 0.3 -0.8 -1.1 -1.0 -0.9 -0.9 -0.6 -1.2 -0.8 3.1 1.5 -1.5 2.5
Standing height 0.2 1.5 6.2 -2.5 0.1 -1.4 -0.1 -0.1 0.3 -0.2 0.3 -1.2 -0.0 2.4 0.4 -1.0 2.2
Length of working week for main job 0.8 0.9 1.7 -0.8 -0.8 -0.9 -1.2 -1.2 -0.4 -1.2 -1.1 -1.0 -1.3 -0.3 -0.4 0.4 1.3
Exposure to tobacco smoke at home 0.3 0.3 1.9 0.4 0.8 -0.4 0.1 0.2 1.4 0.2 0.3 -0.2 0.2 0.9 -0.3 0.1 -0.2
Breastfed as a baby 0.3 0.4 1.5 1.1 -1.2 -0.4 0.1 0.1 0.1 0.0 -0.0 -0.2 -0.1 -0.6 -1.0 0.5 -1.0
Tense / ‘highly strung’ 0.4 0.6 2.6 1.1 -0.7 -0.8 0.2 0.4 1.1 0.5 0.6 0.5 0.3 0.5 0.7 -1.6 -0.8
Seen doctor (GP) for nerves, anxiety, tension or depression 0.7 1.0 3.6 -1.1 -1.3 -1.9 -0.9 -0.9 -0.6 -0.8 -0.5 -0.4 -0.8 1.4 -0.2 -0.8 1.0
Hair/balding pattern: Pattern 4 0.7 1.8 11.3 0.8 -0.0 1.1 0.4 0.3 -0.3 0.1 0.1 0.4 0.2 -3.4 -2.3 2.3 -0.9
Birth weight of first child 1.9 3.5 7.5 -1.4 -0.4 -1.0 -2.7 -2.6 -1.4 -2.5 -2.6 -2.3 -2.4 0.6 0.4 -0.1 2.2
Peak expiratory flow (PEF) 0.3 0.7 1.7 0.2 1.3 0.9 1.0 0.8 1.1 0.7 0.7 1.1 0.6 0.8 0.8 -1.0 -0.1
Pulse wave reflection index 0.5 0.6 3.1 -0.9 0.0 0.9 0.4 0.4 -0.2 0.3 0.3 1.0 0.4 1.8 1.2 -0.4 0.7
Ever highly irritable/argumentative for 2 days 1.2 1.4 3.4 -1.5 -0.9 -0.2 -1.3 -1.4 -0.9 -1.2 -1.3 -1.0 -1.4 1.2 1.0 -0.4 1.9
Loud music exposure frequency 0.4 0.5 2.1 -0.8 0.3 -0.6 -0.7 -0.6 0.3 -0.6 -0.5 0.0 -0.7 1.5 0.4 -0.8 0.9
Qualifications: O levels/GCSEs or equivalent 1.5 2.4 6.3 -0.8 -1.5 -0.9 -2.5 -2.3 -0.2 -2.1 -1.9 -1.3 -2.2 -0.6 -0.6 -0.4 1.5
Mouth/teeth dental problems: Bleeding gums 1.0 1.3 5.8 -0.9 -1.4 -2.4 -1.1 -1.1 -0.4 -1.0 -1.1 -0.8 -1.0 -0.3 -1.0 0.8 1.2
Blood clot in the leg (DVT) 1.4 1.8 5.6 -2.2 0.3 -1.3 -1.2 -1.2 -1.1 -1.2 -1.1 -1.2 -1.1 0.0 -1.0 1.4 2.4
Medication: Paracetamol 0.7 1.2 3.0 0.9 -0.4 1.1 1.3 1.4 1.7 1.1 1.1 1.2 1.3 0.1 -1.1 0.5 -1.1
Headache pain in last month 0.1 0.2 0.8 0.3 0.3 0.2 0.5 0.5 0.9 0.6 0.7 -0.1 0.5 0.4 -0.7 0.1 -0.4
Medication for cholesterol, blood pressure or diabetes 0.4 0.7 3.7 0.7 0.5 0.6 -0.6 -0.7 1.9 -0.7 -0.5 -1.1 -0.8 0.3 -0.3 -0.9 -0.2
Glaucoma (self-reported) 1.2 1.4 2.8 0.4 0.7 1.0 1.4 1.5 0.7 1.7 1.7 0.8 1.6 1.4 0.5 -1.1 -0.8
Gout (self-reported) 1.5 2.1 4.3 -0.6 1.2 1.4 1.7 1.7 -0.2 1.8 1.8 1.8 1.7 2.1 0.9 -1.3 -0.2
Hypothyroidism/myxoedema (self-reported) 5.7 11.1 21.0 -4.2 -1.5 -2.4 -4.5 -4.2 -3.7 -4.1 -4.1 -2.4 -3.6 -1.3 -0.3 1.8 4.6
Medication: Amlodipine 0.5 0.7 2.3 1.0 0.3 1.5 0.5 0.3 0.4 0.3 0.2 1.5 0.2 -1.2 -0.8 1.2 -0.5
Medication: Ventolin 100micrograms inhaler 4.6 5.9 10.8 -2.2 -0.2 -2.0 -3.3 -3.3 -2.5 -3.0 -2.9 -3.1 -3.1 0.2 0.2 0.4 3.0
Birth weight 1.1 2.4 4.8 -1.6 -0.1 -1.6 -2.1 -2.0 -1.1 -1.9 -1.8 -1.9 -1.8 -0.6 -0.4 0.1 2.2
Chronic bronchitis/emphysema (mother) 0.6 0.7 3.8 -0.6 -0.4 -2.0 -0.6 -0.6 0.0 -0.6 -0.6 -1.3 -0.7 -0.6 -0.2 1.0 0.6
High blood pressure (siblings) 1.2 1.8 3.3 0.5 1.7 0.7 1.6 1.5 0.6 1.7 1.5 1.8 1.5 0.7 1.4 -1.6 -0.8
Forced vital capacity (FVC), Best measure 0.1 0.2 1.3 -1.2 0.4 -0.4 0.0 -0.1 0.2 -0.2 0.1 -0.2 -0.1 0.1 0.1 -0.3 0.9
Body fat percentage 0.8 3.2 14.7 -0.4 3.8 1.1 0.9 1.2 0.8 1.3 1.3 1.2 1.2 3.6 2.1 -1.1 -0.3
Leg fat percentage (right) 0.9 3.2 13.2 -0.0 3.6 2.1 1.1 1.4 0.5 1.4 1.4 1.8 1.4 2.9 2.2 -0.6 -0.8
Arm fat-free mass (right) 0.6 2.8 15.3 -2.4 0.9 -0.2 -1.0 -0.8 -0.7 -0.6 -0.3 -0.8 -0.6 3.9 2.3 -2.0 2.2
Exposure to tobacco smoke outside home 0.5 0.7 3.1 1.1 -0.2 -0.1 0.6 0.6 1.8 0.7 0.6 0.6 0.6 1.1 -0.5 -0.7 -0.9
Comparative body size at age 10 0.5 1.4 6.2 -1.6 1.4 0.1 -0.7 -0.4 -0.5 -0.1 -0.3 -0.1 -0.4 2.2 2.5 -1.3 1.4
Number of full brothers 0.1 0.2 1.0 -0.5 0.8 1.0 0.1 0.0 0.1 -0.0 0.0 -0.2 -0.0 0.3 0.5 -0.3 0.4
Worry too long after embarrassment 1.7 2.9 5.4 0.1 -2.3 -1.8 -1.9 -1.9 -0.8 -1.9 -1.8 -2.1 -1.9 -1.9 -2.2 0.6 0.6
Seen a psychiatrist for nerves, anxiety, tension or depression 2.0 2.6 4.6 -1.2 -1.5 -1.1 -2.1 -2.2 -1.2 -2.1 -1.9 -1.9 -2.0 -0.0 -1.4 0.6 1.7
Wheeze or whistling in the chest in last year 0.2 0.4 3.2 -0.8 0.5 -0.6 -0.1 -0.1 -0.3 0.1 0.3 -0.5 -0.1 1.8 0.1 -0.2 0.7
Number of children fathered 0.6 0.6 2.0 1.2 0.4 0.4 0.6 0.7 0.7 0.6 0.6 0.7 0.6 -1.3 -0.4 0.5 -1.4
Reason for reducing amount of alcohol drunk: Health precaution 1.3 1.6 8.9 0.1 -0.2 -2.3 0.5 0.4 1.2 0.3 0.6 -0.7 0.5 -0.7 -3.0 2.0 -0.2
Age at first live birth 0.7 1.3 3.0 -0.9 0.3 -1.1 -1.3 -1.2 -0.7 -1.1 -1.1 -1.7 -1.2 -1.1 1.3 -1.0 1.3
Pulse wave peak to peak time 0.9 1.1 2.7 0.1 -1.1 -0.6 -1.5 -1.4 -0.7 -1.4 -1.3 -1.6 -1.3 -0.8 -0.3 -0.3 0.2
Health satisfaction 0.1 0.2 0.9 -0.1 0.6 0.3 -0.3 -0.2 -0.9 -0.1 -0.2 1.0 -0.1 0.0 0.5 -0.3 0.2
Shortness of breath walking on level ground 0.8 0.9 1.8 -0.7 0.4 -0.2 -1.4 -1.1 -0.3 -1.0 -1.2 -0.9 -1.1 1.3 1.0 -0.6 1.1
Qualifications: College or University degree 0.2 0.5 1.7 0.2 -1.2 -0.5 -0.8 -0.7 0.4 -0.5 -0.7 -0.5 -0.6 0.5 0.9 -1.3 0.5
Eye problems/disorders: None of the above 0.5 0.6 0.9 0.3 0.7 0.5 -0.6 -0.9 1.0 -0.9 -0.9 -0.9 -0.9 -0.8 -0.5 0.8 0.4
Mouth/teeth dental problems: Loose teeth 1.3 1.6 8.3 -0.0 1.3 1.1 1.0 1.0 -0.1 1.1 0.9 0.7 0.9 2.9 1.9 -1.3 -0.5
Emphysema/chronic bronchitis 1.0 1.2 3.1 0.1 1.8 0.4 0.9 0.9 1.3 1.1 1.1 1.2 0.9 1.7 0.9 -1.1 -0.5
Medication for pain relief, constipation, heartburn 1.5 2.6 5.1 -0.9 -1.1 -2.0 -2.0 -2.2 -0.7 -2.0 -1.8 -2.2 -2.2 -1.0 -0.6 0.4 1.7
Neck or shoulder pain in last month 0.4 0.5 2.1 -1.3 -0.9 -1.5 -0.4 -0.4 -0.1 -0.3 -0.3 -0.6 -0.3 0.3 -0.2 0.3 1.1
Medication: Blood pressure 1.7 2.9 9.7 0.8 1.4 1.0 2.1 2.2 0.5 2.3 2.0 3.1 2.3 0.3 1.2 -0.4 -1.5
Angina (self-reported) 3.3 4.3 8.2 1.8 2.4 2.9 2.2 2.3 1.2 2.3 2.4 2.3 2.1 1.1 1.2 -1.6 -2.4
Migraine (self-reported) 0.6 0.7 2.1 -0.6 -0.2 -1.3 -0.9 -1.0 -0.9 -0.9 -0.9 -1.4 -0.8 -0.3 -0.1 -0.0 0.7
Medication: Ibuprofen 1.3 1.6 3.5 0.4 -0.6 1.3 1.6 1.6 0.4 1.6 1.5 1.9 1.7 0.9 0.3 -0.8 -1.3
Medication: Allopurinol 0.8 1.0 2.6 -0.3 -0.3 0.4 1.3 1.3 -0.1 1.4 1.4 1.1 1.4 1.6 -0.5 -0.6 -0.4
Medication: Omeprazole 1.9 2.2 7.3 0.6 1.0 0.3 1.4 1.5 1.0 1.6 1.5 1.3 1.7 2.7 1.8 -1.7 -1.0
Medication: Seretide 50 evohaler 0.2 0.3 1.1 0.7 0.1 0.0 0.3 0.2 -0.5 0.3 0.1 0.3 0.2 -0.8 -1.0 0.8 -0.6
Mean time to correctly identify matches 0.4 0.7 2.7 -1.4 0.1 -1.6 -0.6 -0.6 -1.2 -0.5 -0.2 -0.5 -0.6 -0.3 -0.4 0.9 0.9
Heart disease (mother) 0.7 0.8 7.0 -1.0 1.1 -0.2 0.3 0.2 0.4 0.1 0.2 -0.5 0.2 -0.8 -0.4 2.6 0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.3 0.3 1.4 0.5 0.9 -0.5 -0.2 -0.2 0.2 -0.3 -0.0 -0.2 -0.3 -0.7 -0.9 1.2 -0.0
Whole body fat mass 0.8 3.4 16.6 -0.9 3.8 1.0 0.6 0.9 0.5 1.0 1.1 0.9 0.9 4.1 2.6 -1.6 0.3
Leg fat mass (right) 0.8 3.1 15.0 -0.9 3.5 1.3 0.7 1.0 0.3 1.1 1.2 1.1 1.0 3.9 2.5 -1.3 0.1
Arm predicted mass (right) 0.6 2.9 14.1 -2.7 1.0 -0.4 -0.9 -0.7 -1.0 -0.6 -0.3 -0.8 -0.5 3.8 2.4 -1.8 2.3
Pulse rate, automated reading 1.8 5.9 18.2 3.1 0.5 2.7 2.2 2.4 4.3 2.4 2.4 2.8 2.4 1.2 0.6 -1.7 -2.6
Alcohol intake frequency. 1.0 2.4 7.3 -2.7 -0.4 0.1 -1.3 -1.4 -0.6 -1.6 -1.4 -0.4 -1.4 -1.1 -1.1 2.7 2.5
Comparative height size at age 10 0.7 3.8 12.2 -2.8 0.7 -3.5 -1.8 -1.6 -1.7 -1.6 -0.9 -3.1 -1.5 1.2 -0.7 0.7 2.6
Number of full sisters 0.8 0.9 2.6 -0.3 0.1 -0.8 1.4 1.4 0.6 1.4 1.6 0.5 1.5 0.7 -0.4 0.3 -0.4
Suffer from ‘nerves’ 1.0 1.6 4.5 -1.6 -0.9 -2.1 -1.1 -1.1 -1.2 -1.0 -0.9 -1.9 -1.0 -1.1 0.3 0.4 1.6
Overall health rating 0.4 0.8 2.7 -0.6 1.0 -1.0 0.8 1.0 0.8 1.0 1.0 1.6 1.1 0.2 0.3 -0.6 0.2
Chest pain or discomfort 0.6 0.8 3.3 -0.7 0.3 -1.5 -0.8 -0.5 -0.4 -0.3 -0.3 -0.6 -0.4 1.8 0.6 -1.6 0.8
Had major operations 0.4 0.5 2.2 -0.4 -0.2 0.1 0.6 0.7 0.4 0.7 0.7 0.9 0.6 1.5 -1.0 0.4 -0.1
Age at last live birth 0.2 0.3 0.9 -0.6 0.4 -0.2 -0.5 -0.4 0.3 -0.4 -0.5 -0.9 -0.3 0.5 0.9 -0.6 0.8
Family relationship satisfaction 1.8 2.2 4.5 -1.3 -1.4 -1.2 -1.9 -1.8 -2.1 -1.6 -1.7 -1.5 -1.7 -0.0 0.0 -0.1 1.8
Leg pain on walking 1.1 1.3 2.8 -1.1 -0.7 -1.0 -1.5 -1.5 -1.0 -1.5 -1.7 -0.9 -1.6 -0.2 -0.1 0.4 1.4
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.4 1.2 -0.0 0.0 -0.1 0.8 0.7 0.1 0.6 0.7 0.7 0.6 -0.9 -0.8 1.1 -0.4
Commuting to job workplace: Car/motor vehicle 1.4 1.6 5.5 -0.1 -0.5 -0.2 -1.6 -1.6 -2.3 -1.6 -1.8 -1.1 -1.6 1.0 0.9 -0.4 0.5
Illness, injury, bereavement, stress in last 2 years 0.8 1.0 2.5 -0.5 -1.3 -0.4 -1.2 -1.2 -1.6 -1.3 -1.4 -0.5 -1.2 -0.1 0.0 0.6 1.0
Medication: Aspirin 3.4 4.5 7.9 0.2 2.7 2.0 2.5 2.8 0.3 2.8 2.7 2.3 2.8 1.8 1.7 -1.0 -1.5
Supplements: Vitamin C 0.7 0.9 5.7 0.8 -0.2 -0.5 -0.1 0.2 0.3 0.3 0.2 0.7 0.1 1.4 1.5 -2.4 -0.5
Knee pain experienced in last month 0.5 0.8 2.2 -1.2 -1.5 -1.1 -1.0 -0.8 -1.1 -0.8 -0.9 -0.2 -0.9 -0.0 0.5 -0.2 1.1
Hypertension (Self-reported) 1.3 3.7 9.8 1.7 0.7 2.5 2.3 2.2 1.3 2.2 2.0 3.1 2.2 -0.0 -0.9 1.1 -2.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.0 1.2 2.7 0.8 0.7 -0.0 1.4 1.4 0.9 1.3 1.5 0.6 1.6 0.8 -1.2 0.5 -1.3
Illnesses of father: Heart disease 1.7 2.3 6.6 -2.6 0.2 -0.9 -1.5 -1.4 -1.3 -1.3 -1.5 -0.7 -1.3 2.1 1.7 -1.2 2.2
Illnesses of siblings: Diabetes 0.3 0.3 2.3 -0.0 0.3 1.5 -0.1 0.0 -0.6 -0.1 -0.3 0.5 0.0 0.7 1.0 -0.3 0.0
Smoking status: Previous 1.0 1.5 5.5 -0.8 2.4 -0.3 1.3 1.3 0.2 1.4 1.5 1.2 1.3 1.7 -0.4 0.7 -0.2
Forced expiratory volume in 1-second (FEV1), predicted 0.4 0.7 3.3 -1.6 -0.4 -0.7 -0.6 -0.4 0.6 -0.5 -0.1 -0.5 -0.4 1.8 -0.3 0.1 1.5
Whole body fat-free mass 0.5 3.0 11.7 -2.8 0.5 -0.8 -1.3 -1.2 -1.0 -1.0 -0.7 -1.2 -1.0 3.4 1.9 -1.7 2.7
Leg fat-free mass (right) 0.5 2.5 13.4 -2.3 0.6 -0.7 -0.8 -0.7 -0.4 -0.6 -0.3 -0.8 -0.5 3.7 1.8 -2.2 2.3
Arm fat percentage (left) 0.8 3.1 12.5 0.2 3.5 1.4 1.2 1.4 1.1 1.5 1.5 1.3 1.4 3.2 2.0 -1.5 -0.8
Average weekly red wine intake 0.2 0.3 0.7 0.4 0.1 -0.3 -0.8 -0.7 -0.3 -0.6 -0.7 -0.6 -0.8 0.4 -0.8 0.0 -0.1
Handedness (chirality/laterality): Left-handed 0.6 0.8 1.4 1.2 -0.2 0.9 1.0 1.0 1.0 1.0 1.2 0.7 1.1 -0.1 -0.3 -0.5 -1.1
Mood swings 0.2 0.4 0.8 -0.2 -0.6 -0.1 -0.7 -0.8 0.9 -0.9 -0.8 -0.3 -0.8 -0.3 -0.7 0.1 0.4
Loneliness, isolation 0.3 0.4 1.2 1.1 0.1 -0.1 -0.4 -0.3 1.1 -0.3 -0.2 -0.7 -0.6 -0.6 -0.8 0.1 -0.6
Long-standing illness, disability or infirmity 1.7 2.6 7.5 -2.4 -0.1 -0.8 -2.1 -2.0 -1.0 -1.9 -1.8 -0.4 -1.8 1.3 -0.2 0.4 2.7
Ever had bowel cancer screening 0.7 0.9 5.9 0.3 0.6 1.1 0.4 0.4 1.6 0.6 0.5 0.1 0.5 2.4 -0.0 -0.8 -0.1
Diabetes diagnosed by doctor 0.4 0.6 1.2 -0.3 -0.7 0.7 1.1 1.0 -0.9 1.0 1.1 0.5 1.0 -0.3 -0.5 1.0 -0.3
Ever had stillbirth, spontaneous miscarriage or termination 0.5 0.5 1.6 -0.7 0.7 1.1 -0.1 -0.2 0.9 -0.1 -0.0 -0.1 -0.2 1.1 -0.6 1.2 0.7
Friendships satisfaction 3.7 4.6 7.5 -1.6 -1.0 -1.0 -2.7 -2.7 -2.5 -2.6 -2.7 -1.9 -2.6 -2.1 -1.2 1.9 2.2
Qualifications: nursing, teaching 0.3 0.4 0.9 -0.7 0.2 -0.4 -0.7 -0.7 -0.1 -0.6 -0.9 -0.4 -0.9 0.8 0.5 0.7 0.9
Commuting to job workplace: Walk 2.8 3.0 6.6 -1.1 1.9 1.7 2.2 2.3 0.9 2.3 2.3 2.6 2.3 1.0 0.8 -0.4 -0.3
Eye problems/disorders: Cataract 0.3 0.3 2.1 -0.4 -0.5 -0.3 0.1 0.3 -1.4 0.4 0.4 0.3 0.5 -0.4 0.7 -0.8 -0.3
Mouth/teeth dental problems: Mouth ulcers 1.1 1.8 4.0 -0.5 -1.2 -1.5 -1.6 -1.4 -2.0 -1.6 -1.8 -1.4 -1.7 -0.3 0.5 0.7 0.9
Medication for cholesterol 1.4 2.1 4.8 -1.1 -0.9 -2.2 -1.9 -1.7 -1.4 -1.7 -1.8 -1.5 -1.7 -0.1 1.0 -0.7 1.3
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.2 1.5 4.6 -0.8 -0.9 -2.1 -1.3 -1.2 -0.8 -1.2 -1.2 -1.9 -1.0 0.1 -0.6 0.7 1.4
Back pain experienced in last month 0.3 0.4 1.5 -1.2 1.2 -0.1 0.4 0.4 -0.2 0.4 0.3 0.8 0.7 0.4 0.2 0.5 0.5
Mineral and other dietary supplements 0.3 0.3 1.4 -0.3 -0.1 1.1 0.4 0.4 0.5 0.3 0.4 0.9 0.3 1.2 0.2 0.1 0.4
Breast cancer (self-reported) 0.5 0.5 2.0 0.4 1.4 -0.3 -0.3 -0.2 0.0 -0.2 -0.0 -0.7 -0.2 -1.4 -1.0 1.4 -0.2
Asthma (self-reported) 3.8 7.6 13.4 -3.2 -0.8 -2.8 -3.6 -3.4 -3.0 -3.3 -3.1 -3.0 -3.2 0.5 0.7 0.4 3.7
Osteoporosis (self-reported) 3.1 3.9 8.6 -0.4 -1.8 -2.9 -2.6 -2.5 -0.4 -2.5 -2.4 -2.5 -2.4 -0.6 -1.3 0.9 1.5
Osteoarthritis (self-reported) 0.5 0.6 2.7 1.6 -0.4 0.3 0.5 0.5 0.5 0.6 0.3 -0.2 0.5 0.8 0.4 -1.4 -1.4
Medication: Aspirin 2.0 2.6 5.8 0.0 2.4 1.7 1.6 1.9 -0.2 1.9 1.8 1.8 1.9 1.6 1.8 -0.4 -1.1
Medication: Gliclazide 0.8 0.9 1.9 -0.2 1.0 -0.3 1.2 1.3 -0.4 1.4 1.2 0.3 1.4 1.3 0.1 -0.7 -0.6
Illnesses of father: None of the above (group 1) 1.0 1.2 5.5 1.5 -1.0 -0.2 0.2 0.1 0.5 -0.0 0.2 -0.4 -0.0 -2.3 -2.2 1.3 -1.0
Smoking status: Current 0.3 0.5 1.1 -0.4 0.5 0.1 -0.9 -0.9 -0.5 -0.8 -0.9 -1.0 -1.0 0.1 1.0 -0.3 0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage 3.0 6.4 12.2 1.8 2.5 2.4 3.5 3.3 1.9 3.2 3.1 2.7 3.2 0.5 0.9 -1.5 -2.7
Whole body water mass 0.5 3.0 12.1 -2.7 0.4 -0.9 -1.3 -1.1 -1.0 -1.0 -0.6 -1.2 -0.9 3.5 1.9 -1.8 2.6
Leg predicted mass (right) 0.5 2.5 13.6 -2.3 0.7 -0.7 -0.8 -0.6 -0.4 -0.5 -0.2 -0.8 -0.5 3.7 1.8 -2.1 2.2
Arm fat mass (left) 0.8 3.2 16.1 -0.8 3.4 1.1 0.7 0.9 0.7 1.0 1.2 0.9 1.0 4.0 2.4 -1.8 0.2
Number of self-reported non-cancer illnesses 1.3 2.3 5.6 -2.4 -0.3 -0.7 -2.0 -1.7 -1.5 -1.6 -1.5 -0.7 -1.5 1.4 -0.4 1.3 2.3
Average weekly champagne plus white wine intake 0.2 0.2 1.9 0.5 -1.4 0.2 -0.2 -0.2 -0.4 -0.2 -0.4 0.1 -0.2 0.6 -0.3 -0.3 -0.0
Miserableness 1.6 2.7 6.0 -0.9 -1.6 -0.8 -2.3 -2.5 -0.8 -2.3 -2.3 -1.5 -2.4 0.0 0.5 -0.7 1.7
Guilty feelings 1.0 1.6 2.6 -1.1 -1.4 -1.5 -1.5 -1.6 -0.5 -1.4 -1.4 -1.2 -1.6 -0.8 -0.3 0.4 1.6
Wears glasses or contact lenses 0.7 0.8 1.8 -0.4 1.2 -0.0 -1.3 -1.2 -0.3 -1.0 -1.3 -0.2 -1.2 0.9 0.7 -0.2 0.8
Ever taken oral contraceptive pill 0.9 1.0 3.0 -1.1 -0.7 -0.6 -1.0 -1.0 -0.3 -0.9 -1.0 0.0 -1.0 1.6 0.3 -1.7 1.4
Hearing aid user 4.4 5.0 14.8 -3.8 -0.4 -3.5 -1.8 -1.8 -2.4 -1.9 -1.8 -2.0 -1.5 0.7 -0.7 1.6 3.7
Mother’s age at death 0.6 0.7 2.2 1.2 0.8 -1.5 -0.4 -0.5 0.5 -0.6 -0.8 -1.4 -0.6 -1.4 -0.3 0.2 -0.4
Financial situation satisfaction 0.7 0.8 1.9 0.3 -0.4 -0.3 -1.3 -1.4 -0.1 -1.1 -1.3 -1.1 -1.3 0.5 0.6 -0.6 0.7
Tinnitus: Yes, now most or all of the time 0.5 0.6 2.9 -1.7 -0.3 -0.5 -0.3 -0.3 -1.0 -0.2 -0.2 -0.2 -0.3 1.3 0.9 0.1 1.3
Commuting to job workplace: Public transport 0.7 0.8 3.1 0.6 0.9 0.6 0.3 0.6 1.8 0.6 0.8 0.7 0.7 0.9 1.1 -1.4 -0.7
Eye problems/disorders: Glaucoma 0.6 0.7 1.5 0.4 -0.0 0.3 0.9 1.1 0.3 1.2 1.2 0.9 1.1 1.1 0.3 -0.6 -0.8
Medication: Blood pressure 0.9 1.6 6.1 1.4 0.2 2.5 1.3 1.2 1.6 1.1 1.2 1.5 1.2 0.1 -0.9 0.8 -1.0
Pain type(s) experienced in last month: Hip pain 1.0 1.2 2.4 -1.2 0.6 -0.8 -1.6 -1.5 -0.1 -1.3 -1.3 -0.2 -1.4 -0.3 1.1 -0.9 1.5
Supplements: Fish oil (including cod liver oil) 0.2 0.2 0.8 -0.3 0.5 0.2 -0.4 -0.5 -0.3 -0.4 -0.6 -0.4 -0.5 -0.9 0.3 0.5 0.3
High cholesterol (Self-reported) 0.4 0.7 1.4 -0.1 0.1 0.8 1.1 1.1 -1.2 1.1 1.2 1.2 1.0 -0.1 0.4 0.5 -0.5
Medication: Bendroflumethiazide 1.2 1.9 4.4 1.9 -0.5 -0.0 1.5 1.5 1.4 1.4 1.4 1.2 1.6 -0.9 -2.1 0.4 -1.6
Medication: Paracetamol 0.6 0.9 1.4 1.0 0.2 1.0 1.0 1.1 0.7 1.0 0.9 1.0 0.9 1.2 0.5 -0.8 -1.2
Medication: Lisinopril 0.7 0.8 2.7 -1.3 -0.1 1.1 -0.6 -0.8 -1.6 -0.8 -1.1 0.6 -0.6 0.4 0.7 0.4 1.4
Medication: Atorvastatin 3.8 4.8 7.6 1.8 2.5 2.6 2.7 2.7 0.7 2.6 2.6 1.9 2.8 1.8 0.2 -0.6 -2.4
Illnesses of father: High blood pressure 4.8 5.9 9.2 2.0 1.8 1.6 2.5 2.7 1.6 3.0 2.5 2.8 2.7 2.7 1.9 -2.9 -2.5
Alcohol drinker status: Never 2.0 2.4 4.3 -1.4 -0.7 -1.1 -1.8 -1.8 -1.0 -2.0 -1.9 -2.1 -1.7 -1.0 -0.7 1.2 2.0
Ever smoked 0.2 0.4 1.4 -0.0 1.2 -0.2 0.3 0.4 0.3 0.5 0.7 0.1 0.3 1.2 -1.0 0.2 -0.4
Basal metabolic rate 0.5 3.0 15.4 -2.7 1.1 -0.4 -1.0 -0.8 -0.7 -0.7 -0.4 -0.9 -0.7 3.9 2.2 -1.9 2.5
Leg fat percentage (left) 1.0 3.6 12.8 0.1 3.6 1.9 1.2 1.5 0.7 1.6 1.5 1.9 1.5 3.5 2.4 -1.0 -0.9
Arm fat-free mass (left) 0.6 2.9 15.5 -2.6 1.0 -0.1 -1.0 -0.8 -1.0 -0.7 -0.4 -0.8 -0.6 3.9 2.1 -1.7 2.4
Number of operations (self-reported) 0.5 0.8 3.2 0.3 1.4 0.6 0.7 0.8 0.9 0.8 0.8 0.9 0.6 1.8 -0.6 0.3 -0.7
Average weekly beer plus cider intake 0.2 0.2 0.9 -0.9 0.9 0.2 -0.1 -0.0 -0.8 -0.1 -0.1 -0.6 0.0 0.3 0.0 0.3 0.4
Irritability 0.9 1.6 4.2 1.1 0.9 1.6 1.4 1.2 2.0 1.3 1.2 1.6 1.1 0.6 0.5 -0.8 -1.2
Risk taking 1.3 1.9 7.1 0.1 1.9 1.4 0.9 1.2 0.0 1.3 1.2 0.7 1.1 1.8 2.7 -1.7 -0.9
Ever had prostate specific antigen (PSA) test 1.3 1.5 3.0 -0.8 -0.5 -1.0 -1.6 -1.6 -1.1 -1.5 -1.4 -1.7 -1.6 0.2 0.6 0.2 1.5
Fractured/broken bones in last 5 years 0.2 0.3 1.7 -0.4 -1.3 -1.2 -0.4 -0.3 -0.6 -0.3 -0.3 -0.2 -0.2 -0.5 -0.3 0.2 0.2
Age started oral contraceptive pill 0.8 1.0 3.0 0.7 1.7 1.6 0.7 0.8 -0.2 0.8 0.5 1.6 0.8 -0.5 1.0 -0.5 -0.9
Diastolic blood pressure, automated reading 4.4 13.5 22.4 3.6 1.3 3.0 4.4 4.5 4.7 4.4 4.2 4.5 4.5 2.4 1.1 -1.7 -3.9
Ever depressed for a whole week 2.3 2.9 5.1 -1.7 -0.9 -0.2 -2.2 -2.2 -1.2 -2.0 -1.9 -1.7 -2.2 1.9 1.2 -0.2 2.2
Unable to work because of sickness or disability 0.6 0.7 2.8 0.5 0.2 0.8 0.4 0.6 1.6 0.6 0.5 1.0 0.7 1.7 -0.4 -1.2 -0.3
Commuting to job workplace: Cycle 0.1 0.1 0.4 -0.1 -0.6 -0.5 -0.1 -0.1 0.2 -0.1 0.1 0.3 -0.3 -0.2 0.0 -0.4 0.3
Myopia 0.1 0.1 0.5 -0.2 0.7 0.5 0.3 0.4 0.3 0.6 0.5 0.2 0.3 0.2 0.1 -0.0 0.1
Vascular/heart problems diagnosed by doctor 1.2 3.4 8.9 -1.4 -0.6 -2.4 -2.2 -2.2 -1.2 -2.2 -2.1 -3.0 -2.2 -0.2 0.7 -0.7 1.8
Cholesterol lowering medication 1.1 1.6 4.8 -0.0 0.9 2.2 1.7 1.7 -0.2 1.6 1.5 1.5 1.6 -0.3 -0.3 0.8 -0.8
Medication: Omeprazole (e.g. Zanprol) 1.0 1.3 3.7 1.1 0.8 0.4 1.0 1.1 0.7 1.2 1.1 0.8 1.3 1.9 1.3 -1.2 -1.1
Pain experienced in last month 0.1 0.2 0.8 0.1 0.3 0.5 -0.4 -0.4 -0.2 -0.4 -0.3 -0.3 -0.5 0.5 0.9 0.1 0.6
Supplements: Calcium 1.3 1.4 5.7 -0.1 -1.3 -2.4 -1.0 -1.0 0.2 -1.1 -0.9 -1.4 -1.1 -1.3 -1.5 1.3 0.3
Basal cell carcinoma (self-reported) 0.7 0.8 2.7 0.0 0.5 0.2 1.2 1.3 1.0 1.3 1.6 0.6 1.2 -0.8 0.1 0.2 -0.4
Heart attack/myocardial infarction (self-reported) 0.4 0.5 1.8 0.3 0.6 -0.8 -0.6 -0.5 -1.2 -0.6 -0.5 -1.3 -0.5 0.2 -1.2 0.6 -0.0
Deep venous thrombosis (DVT) (self-reported) 1.8 2.3 7.5 -2.5 0.2 -1.5 -1.4 -1.4 -1.3 -1.5 -1.3 -1.5 -1.3 -0.0 -0.6 1.3 2.7
Heart disease (siblings) 0.5 0.6 2.1 0.8 1.2 0.8 0.2 0.2 -0.7 0.3 0.2 -0.0 0.1 0.4 1.5 -1.1 -0.9
Alcohol drinker status: Previous 0.9 1.0 6.0 -2.5 -1.3 -0.2 0.1 0.1 -0.4 -0.1 -0.0 1.1 0.2 0.3 -0.7 1.5 1.5
Pack years of smoking 2.3 3.3 7.2 2.2 2.5 2.7 1.9 1.9 1.8 1.9 1.9 1.1 1.6 0.7 1.2 -0.9 -2.1
Impedance of whole body 0.2 1.2 3.1 0.9 0.4 0.1 1.1 1.1 1.3 0.9 0.8 0.6 0.9 -1.8 -1.6 1.4 -1.1
Leg fat mass (left) 0.9 3.4 17.1 -0.9 3.5 1.3 0.7 1.0 0.5 1.1 1.2 1.2 1.1 4.1 2.5 -1.4 0.1
Arm predicted mass (left) 0.6 2.9 16.8 -2.8 1.0 -0.2 -0.9 -0.7 -0.8 -0.5 -0.2 -0.7 -0.5 4.1 1.9 -1.8 2.4