Best TWAS P=6.17e-36 · Best GWAS P=4.83e-57 conditioned to 1.98e-25
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | C11orf30 | 0.07 | 0.06 | lasso | 6 | 0.06 | 2.1e-07 | 6.9 | -6.7 | 1.6e-11 | -0.50 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Adipose Visceral Omentum | LRRC32 | 0.21 | 0.00 | enet | 15 | 0.01 | 1.5e-01 | 14.3 | 12.5 | 6.2e-36 | 0.62 | 0.00 | 0.96 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | RP11-111M22.3 | 0.21 | 0.05 | enet | 16 | 0.12 | 1.3e-14 | 5.1 | -5.2 | 2.0e-07 | -0.36 | 0.99 | 0.00 | FALSE |
| 4 | YFS | Blood | LRRC32 | 0.02 | 0.00 | bslmm | 481 | 0.00 | 9.1e-02 | 7.2 | -7.8 | 6.8e-15 | -0.55 | 0.17 | 0.41 | FALSE |