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chr14:34,820,295-36,440,325

Best TWAS P=1.29e-11 · Best GWAS P=1.23e-10 conditioned to 0.0737

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adrenal Gland	PPP2R3C	0.22	0.11	enet	15	0.24	3.2e-09	6.4	6.5	1.1e-10	0.86	0.00	1.00	FALSE
2	GTEx	Colon Transverse	FAM177A1	0.20	0.02	lasso	5	0.01	1.1e-01	5.4	-5.2	1.7e-07	-0.70	0.04	0.24	FALSE
3	GTEx	Esophagus Mucosa	PPP2R3C	0.18	0.17	lasso	5	0.16	1.5e-10	4.9	5.1	3.0e-07	0.70	0.81	0.19	FALSE
4	GTEx	Muscle Skeletal	PPP2R3C	0.06	0.05	lasso	6	0.06	2.8e-06	4.9	5.5	4.3e-08	0.74	0.38	0.55	FALSE
5	GTEx	Muscle Skeletal	FAM177A1	0.16	0.09	enet	35	0.15	6.0e-15	5.3	6.8	1.3e-11	0.79	0.02	0.98	TRUE
6	GTEx	Pancreas	PPP2R3C	0.28	0.18	lasso	8	0.16	4.3e-07	6.4	6.2	6.3e-10	0.89	0.00	1.00	FALSE
7	GTEx	Whole Blood	PPP2R3C	0.25	0.08	enet	24	0.14	3.2e-13	4.9	-6.2	5.1e-10	-0.77	0.63	0.37	FALSE
8	METSIM	Adipose	KIAA0391	0.05	0.03	lasso	3	0.02	5.1e-04	5.5	5.8	7.3e-09	0.71	0.26	0.70	FALSE
9	NTR	Blood	PPP2R3C	0.06	0.04	lasso	5	0.04	4.2e-14	5.0	-5.3	1.3e-07	-0.60	0.39	0.61	FALSE
10	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PPP2R3C	0.10	0.07	lasso	7	0.07	2.3e-06	4.9	5.7	1.6e-08	0.74	0.01	0.99	FALSE
11	The Cancer Genome Atlas	Breast Invasive Carcinoma	PPP2R3C	0.08	0.10	blup	51	0.10	8.4e-20	5.3	6.0	2.7e-09	0.75	0.01	0.99	FALSE
12	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	PPP2R3C	0.18	0.12	enet	7	0.15	6.1e-08	4.9	5.7	1.1e-08	0.68	0.02	0.98	FALSE
13	The Cancer Genome Atlas	Colon Adenocarcinoma	PPP2R3C	0.18	0.15	lasso	3	0.13	7.7e-08	4.9	5.3	9.5e-08	0.72	0.04	0.96	FALSE
14	The Cancer Genome Atlas	Esophageal Carcinoma	PPP2R3C	0.14	0.00	blup	51	0.02	5.8e-02	4.9	5.6	2.4e-08	0.71	0.01	0.64	FALSE
15	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PPP2R3C	0.09	0.06	enet	7	0.07	7.0e-08	4.9	5.7	1.2e-08	0.69	0.01	0.99	FALSE
16	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PPP2R3C	0.11	0.09	lasso	3	0.10	2.6e-06	5.3	5.3	1.1e-07	0.69	0.01	0.98	FALSE
17	The Cancer Genome Atlas	Lung Adenocarcinoma	PPP2R3C	0.09	0.09	blup	51	0.08	2.4e-09	4.9	5.3	1.1e-07	0.73	0.06	0.94	FALSE
18	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	KIAA0391	0.07	0.01	enet	6	0.05	6.5e-06	-4.0	6.7	1.6e-11	0.70	0.02	0.92	FALSE
19	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	PPP2R3C	0.09	0.10	blup	51	0.10	8.1e-12	4.9	5.7	1.2e-08	0.74	0.04	0.96	FALSE
20	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	FAM177A1	0.08	0.00	blup	54	0.02	1.0e-02	-3.9	5.4	7.1e-08	0.38	0.02	0.09	FALSE
21	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	KIAA0391	0.11	0.04	lasso	3	0.03	3.8e-03	5.6	5.6	2.4e-08	0.66	0.00	0.99	FALSE
22	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	PPP2R3C	0.11	0.08	blup	51	0.08	8.1e-06	5.3	6.1	8.4e-10	0.75	0.01	0.96	FALSE
23	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	PPP2R3C	0.15	0.11	lasso	4	0.09	9.5e-05	5.3	5.4	5.2e-08	0.74	0.02	0.91	FALSE
24	The Cancer Genome Atlas	Testicular Germ Cell Tumors	PPP2R3C	0.14	0.12	lasso	6	0.12	4.6e-05	5.4	5.4	6.6e-08	0.68	0.01	0.96	FALSE
25	The Cancer Genome Atlas	Thyroid Carcinoma	FAM177A1	0.07	0.07	blup	54	0.06	2.1e-06	4.9	-5.3	1.0e-07	-0.70	0.01	0.98	FALSE
26	The Cancer Genome Atlas	Thyroid Carcinoma	PPP2R3C	0.19	0.23	blup	51	0.25	5.4e-24	4.9	6.0	2.0e-09	0.72	0.04	0.96	FALSE
27	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	PPP2R3C	0.17	0.12	enet	6	0.17	1.6e-05	4.9	5.7	1.3e-08	0.71	0.01	0.95	FALSE