[Hub]/) : Traits : Hayfever, allergic rhinitis or eczema :

chr14:34,820,295-36,440,325

Best TWAS P=1.29e-11 · Best GWAS P=1.23e-10 conditioned to 0.0737

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland PPP2R3C 0.22 0.11 enet 15 0.24 3.2e-09 6.4 6.5 1.1e-10 0.86 0.00 1.00 FALSE
2 GTEx Colon Transverse FAM177A1 0.20 0.02 lasso 5 0.01 1.1e-01 5.4 -5.2 1.7e-07 -0.70 0.04 0.24 FALSE
3 GTEx Esophagus Mucosa PPP2R3C 0.18 0.17 lasso 5 0.16 1.5e-10 4.9 5.1 3.0e-07 0.70 0.81 0.19 FALSE
4 GTEx Muscle Skeletal PPP2R3C 0.06 0.05 lasso 6 0.06 2.8e-06 4.9 5.5 4.3e-08 0.74 0.38 0.55 FALSE
5 GTEx Muscle Skeletal FAM177A1 0.16 0.09 enet 35 0.15 6.0e-15 5.3 6.8 1.3e-11 0.79 0.02 0.98 TRUE
6 GTEx Pancreas PPP2R3C 0.28 0.18 lasso 8 0.16 4.3e-07 6.4 6.2 6.3e-10 0.89 0.00 1.00 FALSE
7 GTEx Whole Blood PPP2R3C 0.25 0.08 enet 24 0.14 3.2e-13 4.9 -6.2 5.1e-10 -0.77 0.63 0.37 FALSE
8 METSIM Adipose KIAA0391 0.05 0.03 lasso 3 0.02 5.1e-04 5.5 5.8 7.3e-09 0.71 0.26 0.70 FALSE
9 NTR Blood PPP2R3C 0.06 0.04 lasso 5 0.04 4.2e-14 5.0 -5.3 1.3e-07 -0.60 0.39 0.61 FALSE
10 The Cancer Genome Atlas Bladder Urothelial Carcinoma PPP2R3C 0.10 0.07 lasso 7 0.07 2.3e-06 4.9 5.7 1.6e-08 0.74 0.01 0.99 FALSE
11 The Cancer Genome Atlas Breast Invasive Carcinoma PPP2R3C 0.08 0.10 blup 51 0.10 8.4e-20 5.3 6.0 2.7e-09 0.75 0.01 0.99 FALSE
12 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma PPP2R3C 0.18 0.12 enet 7 0.15 6.1e-08 4.9 5.7 1.1e-08 0.68 0.02 0.98 FALSE
13 The Cancer Genome Atlas Colon Adenocarcinoma PPP2R3C 0.18 0.15 lasso 3 0.13 7.7e-08 4.9 5.3 9.5e-08 0.72 0.04 0.96 FALSE
14 The Cancer Genome Atlas Esophageal Carcinoma PPP2R3C 0.14 0.00 blup 51 0.02 5.8e-02 4.9 5.6 2.4e-08 0.71 0.01 0.64 FALSE
15 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PPP2R3C 0.09 0.06 enet 7 0.07 7.0e-08 4.9 5.7 1.2e-08 0.69 0.01 0.99 FALSE
16 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PPP2R3C 0.11 0.09 lasso 3 0.10 2.6e-06 5.3 5.3 1.1e-07 0.69 0.01 0.98 FALSE
17 The Cancer Genome Atlas Lung Adenocarcinoma PPP2R3C 0.09 0.09 blup 51 0.08 2.4e-09 4.9 5.3 1.1e-07 0.73 0.06 0.94 FALSE
18 The Cancer Genome Atlas Lung Squamous Cell Carcinoma KIAA0391 0.07 0.01 enet 6 0.05 6.5e-06 -4.0 6.7 1.6e-11 0.70 0.02 0.92 FALSE
19 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PPP2R3C 0.09 0.10 blup 51 0.10 8.1e-12 4.9 5.7 1.2e-08 0.74 0.04 0.96 FALSE
20 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma FAM177A1 0.08 0.00 blup 54 0.02 1.0e-02 -3.9 5.4 7.1e-08 0.38 0.02 0.09 FALSE
21 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma KIAA0391 0.11 0.04 lasso 3 0.03 3.8e-03 5.6 5.6 2.4e-08 0.66 0.00 0.99 FALSE
22 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma PPP2R3C 0.11 0.08 blup 51 0.08 8.1e-06 5.3 6.1 8.4e-10 0.75 0.01 0.96 FALSE
23 The Cancer Genome Atlas Pancreatic Adenocarcinoma PPP2R3C 0.15 0.11 lasso 4 0.09 9.5e-05 5.3 5.4 5.2e-08 0.74 0.02 0.91 FALSE
24 The Cancer Genome Atlas Testicular Germ Cell Tumors PPP2R3C 0.14 0.12 lasso 6 0.12 4.6e-05 5.4 5.4 6.6e-08 0.68 0.01 0.96 FALSE
25 The Cancer Genome Atlas Thyroid Carcinoma FAM177A1 0.07 0.07 blup 54 0.06 2.1e-06 4.9 -5.3 1.0e-07 -0.70 0.01 0.98 FALSE
26 The Cancer Genome Atlas Thyroid Carcinoma PPP2R3C 0.19 0.23 blup 51 0.25 5.4e-24 4.9 6.0 2.0e-09 0.72 0.04 0.96 FALSE
27 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma PPP2R3C 0.17 0.12 enet 6 0.17 1.6e-05 4.9 5.7 1.3e-08 0.71 0.01 0.95 FALSE