Hub : Genes

PPP2R3C

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.2550 0.0410 0.0e+00 0.336 0.284 0.327 0.328 0.338 3.5e-42 9.1e-35 7.1e-41 5.1e-41 2.2e-42
2 GTEx Adipose Subcutaneous 0.2120 0.0570 1.6e-07 0.125 NA 0.129 NA 0.137 2.2e-10 NA 1.0e-10 NA 2.6e-11
3 GTEx Adrenal Gland 0.2204 0.0606 1.4e-05 0.113 NA 0.243 NA 0.228 7.3e-05 NA 3.2e-09 NA 1.1e-08
4 GTEx Brain Frontal Cortex BA9 0.2809 0.0898 8.3e-04 0.144 NA 0.085 NA 0.223 1.2e-04 NA 2.9e-03 NA 1.3e-06
5 GTEx Cells Transformed fibroblasts 0.3090 0.0580 4.8e-13 0.105 NA 0.131 NA 0.175 3.0e-08 NA 5.3e-10 NA 4.0e-13
6 GTEx Esophagus Mucosa 0.1830 0.0520 4.2e-07 0.170 NA 0.144 NA 0.155 1.7e-11 NA 6.9e-10 NA 1.5e-10
7 GTEx Muscle Skeletal 0.0592 0.0219 5.3e-04 0.053 NA 0.055 NA 0.057 5.9e-06 NA 4.3e-06 NA 2.8e-06
8 GTEx Pancreas 0.2800 0.0710 7.9e-07 0.176 NA 0.093 NA 0.155 6.9e-08 NA 1.0e-04 NA 4.3e-07
9 GTEx Spleen 0.3530 0.1180 2.2e-03 0.164 NA 0.101 NA 0.169 5.3e-05 NA 1.5e-03 NA 4.2e-05
10 GTEx Testis 0.2330 0.0730 9.9e-06 0.215 NA 0.174 NA 0.229 6.8e-10 NA 3.8e-08 NA 1.6e-10
11 GTEx Thyroid 0.0560 0.0260 8.8e-03 0.001 NA 0.007 NA 0.006 2.6e-01 NA 8.5e-02 NA 1.0e-01
12 GTEx Whole Blood 0.2470 0.0540 1.4e-12 0.084 NA 0.144 NA 0.144 3.4e-08 NA 3.2e-13 NA 3.3e-13
13 METSIM Adipose 0.1481 0.0347 2.8e-16 0.122 0.119 0.117 0.121 0.118 7.9e-18 2.2e-17 3.8e-17 1.2e-17 3.4e-17
14 NTR Blood 0.0595 0.0178 1.1e-09 0.037 0.038 0.043 0.043 0.044 5.8e-12 3.1e-12 8.9e-14 7.6e-14 4.2e-14
15 YFS Blood 0.5283 0.0373 0.0e+00 0.461 0.574 0.597 0.601 0.600 1.4e-171 4.2e-236 2.2e-251 2.4e-254 2.2e-253
16 TCGA Bladder Urothelial Carcinoma 0.1020 0.0430 8.0e-07 0.065 0.063 0.065 NA 0.068 3.3e-06 4.9e-06 3.8e-06 NA 2.3e-06
17 TCGA Breast Invasive Carcinoma 0.0767 0.0252 0.0e+00 0.103 0.100 0.091 NA 0.096 2.5e-20 8.4e-20 4.0e-18 NA 6.3e-19
18 TCGA Cervical Squamous Cell Carcinoma 0.1760 0.0700 3.4e-07 0.117 0.151 0.152 NA 0.149 2.4e-06 7.1e-08 6.1e-08 NA 8.3e-08
19 TCGA Colon Adenocarcinoma 0.1790 0.0680 1.8e-08 0.152 0.124 0.094 NA 0.128 4.3e-09 1.2e-07 4.5e-06 NA 7.7e-08
20 TCGA Esophageal Carcinoma 0.1410 0.0690 2.9e-03 -0.003 0.024 0.005 NA -0.003 4.1e-01 5.8e-02 2.1e-01 NA 4.2e-01
21 TCGA Head and Neck Squamous Cell Carcinoma 0.1909 0.0660 0.0e+00 0.149 0.160 0.152 NA 0.164 2.2e-16 1.5e-17 9.3e-17 NA 5.0e-18
22 TCGA Kidney Renal Clear Cell Carcinoma 0.0923 0.0356 1.2e-07 0.064 0.061 0.066 NA 0.063 1.0e-07 1.9e-07 7.0e-08 NA 1.4e-07
23 TCGA Kidney Renal Papillary Cell Carcinoma 0.1100 0.0480 1.0e-05 0.087 0.070 0.078 NA 0.099 1.1e-05 8.0e-05 3.0e-05 NA 2.6e-06
24 TCGA Brain Lower Grade Glioma 0.0822 0.0342 9.6e-08 0.042 0.075 0.058 NA 0.064 1.3e-05 7.8e-09 3.4e-07 NA 9.2e-08
25 TCGA Lung Adenocarcinoma 0.0917 0.0375 1.2e-08 0.086 0.077 0.068 NA 0.074 3.3e-10 2.4e-09 2.5e-08 NA 5.7e-09
26 TCGA Lung Squamous Cell Carcinoma 0.0926 0.0318 3.6e-12 0.095 0.104 0.099 NA 0.099 6.1e-11 8.1e-12 2.3e-11 NA 2.3e-11
27 TCGA Ovarian Serous Cystadenocarcinoma 0.1130 0.0500 3.4e-05 0.078 0.076 0.068 NA 0.059 6.2e-06 8.1e-06 2.3e-05 NA 7.3e-05
28 TCGA Pancreatic Adenocarcinoma 0.1520 0.0710 2.4e-04 0.111 0.078 0.086 NA 0.094 2.3e-05 3.8e-04 1.9e-04 NA 9.4e-05
29 TCGA Prostate Adenocarcinoma 0.1637 0.0615 8.0e-14 0.133 0.161 0.157 NA 0.157 8.1e-14 1.5e-16 4.2e-16 NA 4.2e-16
30 TCGA Stomach Adenocarcinoma 0.0630 0.0300 3.7e-04 0.056 0.056 0.045 NA 0.050 6.7e-05 6.4e-05 3.3e-04 NA 1.7e-04
31 TCGA Testicular Germ Cell Tumors 0.1370 0.0590 9.7e-05 0.124 0.100 0.109 NA 0.122 3.9e-05 2.1e-04 1.1e-04 NA 4.6e-05
32 TCGA Thyroid Carcinoma 0.1940 0.0580 0.0e+00 0.227 0.248 0.244 NA 0.246 8.3e-22 5.4e-24 1.4e-23 NA 9.2e-24
33 TCGA Uterine Corpus Endometrial Carcinoma 0.1650 0.0730 1.6e-03 0.117 0.110 0.172 NA 0.160 3.9e-04 5.6e-04 1.6e-05 NA 3.2e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33
Bipolar Disorder (2018) 0.2 0.2 1.2 0.1 -0.9 0.1 0.0 -0.1 -0.1 -0.1 0.3 0.1 -1.1 -0.4 -0.2 0.5 0.1 0.3 -0.3 0.3 0.0 -0.2 -0.3 0.2 -0.2 0.8 -0.1 -1.1 -0.3 0.8 0.8 -0.1 -0.7 -0.7 -0.1 -0.9
Bipolar Disorder or Schizophrenia 2.8 6.7 14.1 2.0 -0.7 -2.8 1.3 0.4 -2.4 -2.8 -2.5 2.2 -2.3 -2.4 2.6 1.6 3.5 3.2 -3.2 -2.7 -2.6 -2.7 -2.9 -2.6 -3.3 -2.1 0.2 -3.5 -3.1 -2.3 -2.2 -2.2 -3.3 -2.9 -2.8 -3.8
Depressed Affect (Nagel 2018) 0.5 1.1 4.0 1.3 1.4 -1.3 1.9 1.2 -1.2 -1.0 -1.5 1.2 0.3 0.3 1.0 0.7 0.1 -0.2 -1.0 -0.8 -0.8 -1.1 -0.5 -0.7 -0.4 -1.1 2.0 -1.2 -0.6 -0.9 -1.1 -0.5 -0.2 -1.4 -1.1 -0.8
Depression (Nagel 2018) 3.4 5.2 10.5 3.2 3.0 -1.9 2.7 2.8 -3.0 -2.5 -2.1 3.1 -0.9 -0.4 2.3 2.6 0.2 -0.6 -2.4 -2.2 -2.3 -2.8 -1.9 -2.0 -1.5 -2.2 3.1 -2.6 -2.0 -1.9 -2.5 -1.8 -1.5 -2.8 -2.2 -1.7
Intelligence (Savage-Jansen 2018) 0.3 0.9 7.5 -0.3 -1.7 -0.7 -0.2 -0.8 -0.1 -0.6 -0.4 -0.1 0.7 -0.8 1.0 0.6 2.3 2.7 -0.8 -0.7 -0.5 -0.4 -0.2 -0.4 -1.4 -0.5 -0.8 -0.7 -0.6 -0.6 -0.5 0.0 -0.6 0.6 -0.8 -0.9
Neuroticism (Nagel 2018) 0.4 1.0 5.0 1.3 1.3 -1.0 2.2 1.0 -1.2 -1.0 -1.0 1.4 -0.5 0.2 0.9 0.7 -0.0 0.0 -1.1 -0.8 -0.9 -1.2 -0.3 -0.9 -0.4 -1.2 1.5 -0.8 -0.7 -0.5 -0.9 -0.9 -0.9 -1.0 -0.9 -0.6
Schizophrenia (2018) 5.0 10.4 19.5 2.4 -0.2 -3.8 1.6 0.7 -3.0 -3.5 -3.6 2.7 -2.1 -2.8 3.5 1.7 4.4 3.8 -3.8 -3.7 -3.3 -3.3 -3.5 -3.5 -4.0 -3.4 0.3 -3.7 -3.8 -3.6 -3.4 -2.7 -3.7 -3.1 -3.6 -4.1
Schizophrenia vs Biploar Disorder 2.7 3.5 11.6 0.8 -1.1 -2.3 0.2 -0.8 -1.4 -1.8 -1.7 1.0 -1.1 -1.7 2.0 0.8 3.4 3.3 -2.1 -1.9 -1.9 -1.7 -1.8 -1.8 -2.9 -1.5 -1.4 -1.9 -2.0 -2.1 -1.4 -1.8 -2.3 -0.9 -2.1 -2.5
Worry (Nagel 2018) 0.2 0.4 2.8 0.7 1.2 -0.3 1.7 0.7 -0.6 -0.3 -0.3 0.8 0.2 0.8 0.2 0.1 -0.5 -0.3 -0.5 -0.2 -0.3 -0.5 0.1 -0.5 0.1 -0.9 1.2 0.3 -0.4 -0.1 -0.6 -0.3 -0.5 -0.8 -0.3 -0.2
Alzheimer’s Disease (in mother) 0.6 0.7 1.5 1.1 1.2 -0.0 1.2 1.0 -1.0 -0.6 0.1 1.0 0.3 -0.9 0.5 0.7 -0.6 -1.0 -0.7 -0.8 -1.2 -0.8 -0.5 -0.7 -0.4 -1.2 1.2 -0.3 -0.5 -0.6 -0.8 -1.2 0.2 -1.1 -1.2 -0.3
Alzheimer’s Disease (in father) 5.1 5.6 11.6 2.6 1.8 -2.2 2.7 2.1 -2.6 -2.8 -2.7 2.5 -0.6 -1.2 2.5 2.0 1.9 1.0 -2.6 -2.8 -2.1 -2.6 -2.7 -2.5 -2.0 -2.8 1.8 -2.5 -2.5 -3.4 -3.2 -1.7 -2.0 -2.5 -2.4 -2.2
Alzheimer’s Disease (including proxy) 1.0 1.4 4.0 1.5 1.6 -0.3 1.8 1.7 -1.4 -1.2 -0.7 1.4 1.1 -0.6 0.9 1.3 -0.2 -0.6 -1.1 -1.2 -1.2 -1.3 -1.0 -0.8 -0.5 -1.4 2.0 -0.8 -0.9 -1.8 -1.5 -0.8 0.2 -1.4 -1.5 -0.6
Crohns Disease (2017) 4.4 9.7 16.0 2.8 1.4 -3.9 1.7 1.7 -3.2 -3.4 -4.0 3.0 -0.7 -2.6 3.7 3.2 3.3 3.1 -3.5 -3.6 -3.4 -3.4 -3.0 -3.2 -3.7 -3.5 1.2 -2.7 -3.6 -3.8 -3.7 -2.6 -2.8 -2.9 -3.8 -3.3
Irritable Bowel Disease (IBD) 4.9 11.7 20.8 3.3 2.0 -3.9 2.6 2.2 -3.6 -3.8 -4.4 3.4 -0.3 -3.0 4.0 3.4 3.1 2.4 -3.7 -3.9 -3.7 -3.7 -3.7 -3.3 -3.7 -3.6 1.8 -3.4 -3.9 -4.6 -4.1 -2.8 -2.5 -3.6 -4.3 -3.6
Ulcerative Colitis (UC) 3.2 6.0 13.2 2.5 2.0 -2.4 2.3 2.1 -2.7 -2.8 -3.2 2.5 0.3 -2.0 2.8 2.5 1.8 0.9 -2.5 -2.8 -2.5 -2.6 -3.0 -2.0 -2.2 -2.4 1.8 -2.6 -2.7 -3.6 -3.0 -1.7 -1.2 -2.9 -3.1 -2.4
Major Depression (MDD) 1.9 2.3 4.9 1.6 1.6 -2.0 0.5 1.7 -1.6 -1.5 -2.2 1.6 -1.2 -2.1 1.8 1.6 0.5 0.1 -1.5 -1.5 -1.4 -1.5 -1.4 -1.7 -1.2 -1.7 1.5 -1.4 -1.4 -1.3 -1.8 -1.2 -1.3 -1.6 -1.3 -1.2
Reaction Time 0.3 0.7 2.3 1.1 1.4 -0.5 0.8 1.5 -0.9 -0.7 -0.5 1.1 -0.4 -0.5 0.5 0.5 -0.1 0.0 -0.8 -0.7 -0.7 -0.9 -0.6 -0.9 -0.3 -1.2 1.4 -0.7 -0.7 -0.7 -1.1 -0.5 -0.7 -0.8 -0.6 -0.4
Verbal and Numeric Reasoning (VNR) 0.2 0.5 3.2 -0.5 -1.3 -0.3 -0.7 -0.5 0.2 -0.3 -0.4 -0.3 1.3 -1.1 0.8 -0.1 1.8 1.8 -0.2 -0.6 -0.2 0.0 -0.1 -0.3 -0.9 -0.6 -0.4 -0.3 -0.3 -0.5 -0.6 0.5 0.2 0.9 -0.5 -0.2
Breast Cancer 5.9 14.3 19.9 -4.3 -2.4 3.9 -3.3 -2.6 4.4 4.4 4.2 -4.4 3.3 4.2 -4.4 -4.3 -1.8 -0.8 4.0 4.0 4.4 4.3 3.7 4.3 3.7 4.1 -1.9 3.5 4.0 3.4 3.9 4.5 3.8 3.7 4.1 3.4
Ovarian Cancer 1.2 1.6 3.6 -1.8 -1.8 0.9 -1.0 -1.9 1.6 1.3 0.9 -1.7 1.2 1.3 -1.0 -1.6 0.5 0.9 1.0 1.2 1.4 1.4 1.3 1.5 0.6 1.5 -1.1 0.7 1.3 0.9 1.3 1.6 1.0 1.3 0.9 0.6
Prostate Cancer 0.4 0.6 2.2 -0.9 -0.2 0.7 -1.0 -0.7 0.8 0.7 0.8 -0.8 -0.2 -1.5 -0.8 -0.9 -0.6 -0.4 0.7 0.7 0.5 0.8 0.9 0.4 0.6 0.4 -1.1 1.5 0.8 0.8 0.7 0.0 0.4 0.4 0.7 0.6
Age at First Birth 0.1 0.2 1.8 -0.1 -0.5 0.2 -0.4 -0.1 -0.0 -0.1 0.2 0.1 1.0 0.8 0.1 -0.0 1.1 1.3 -0.4 -0.1 0.1 -0.2 0.3 0.0 -0.4 -0.3 0.4 -0.2 -0.1 -0.2 -0.5 0.6 0.0 -0.1 -0.4 -0.5
Bipolar Disorder (2011) 0.5 0.5 1.1 0.8 -0.2 -0.9 0.2 0.8 -0.8 -0.8 -0.9 0.9 -0.2 -0.3 0.9 1.0 0.8 0.9 -0.9 -0.5 -0.6 -0.9 -0.6 -0.5 -0.7 -0.5 0.8 -1.1 -0.9 -0.4 -0.6 -0.1 -0.7 -0.7 -0.6 -0.9
Body Mass Index (BMI) (2010) 0.2 0.3 1.9 0.1 0.4 0.4 -0.6 0.7 0.1 0.5 0.7 0.0 -0.2 0.4 -0.5 -0.0 -1.2 -1.4 0.6 0.4 0.5 0.3 0.3 0.3 1.0 0.2 1.1 0.2 0.5 0.6 0.1 0.3 0.6 -0.0 0.5 0.7
Coronary Artery Disease (CAD) 0.4 0.5 2.7 0.9 0.9 0.5 1.7 0.8 -0.7 -0.2 0.5 0.9 0.8 0.5 -0.3 0.6 -1.3 -1.5 -0.3 0.3 -0.5 -0.5 -0.1 0.2 0.2 0.0 1.0 -0.1 -0.1 -0.3 0.1 -0.5 0.4 -0.8 -0.6 -0.1
Crohns Disease (2012) 2.3 3.7 10.2 1.5 0.8 -2.8 0.1 1.1 -1.7 -2.1 -3.2 1.6 -0.5 -2.0 2.4 1.9 2.5 2.6 -2.1 -2.2 -1.6 -1.9 -1.6 -1.9 -2.1 -2.0 0.9 -1.7 -2.1 -2.0 -2.4 -0.9 -1.9 -1.6 -2.0 -2.0
Mean Putamen Volume 0.3 0.3 1.1 0.5 -0.8 -0.4 0.9 0.7 -0.4 -0.3 -0.2 0.5 1.0 1.1 0.4 0.7 0.6 0.8 -0.6 0.2 -0.2 -0.5 -0.0 0.3 -0.5 0.2 0.8 -0.6 -0.5 0.1 0.1 0.8 -0.2 -0.5 -0.4 -0.9
Fasting Glucose 0.5 0.6 4.3 -0.6 -1.0 0.4 -0.1 -0.9 0.5 0.3 1.1 -0.4 -0.3 0.5 -0.5 -0.9 0.1 0.8 0.5 0.7 0.5 0.3 0.9 1.5 0.3 2.1 -0.9 1.0 0.6 0.9 1.5 0.2 0.1 0.8 0.7 0.5
HbA1C 0.6 0.6 4.1 1.0 1.4 -0.5 1.0 1.6 -0.9 -0.4 -0.2 0.9 0.8 0.3 0.6 1.6 -0.5 -0.0 -0.8 -0.2 -0.6 -0.9 -0.0 0.0 -0.2 -0.1 2.0 -1.0 -0.3 -0.4 -0.2 -0.1 0.1 -0.9 -0.9 -0.5
HDL Cholesterol 0.8 1.3 2.4 1.3 1.5 -1.2 0.2 1.3 -1.2 -1.0 -1.5 1.2 -1.3 -0.1 1.1 1.2 0.5 0.1 -1.2 -1.4 -1.0 -1.2 -1.5 -1.2 -0.6 -1.2 1.0 -1.1 -1.1 -1.5 -1.5 -0.9 -1.0 -1.4 -0.8 -0.8
LDL Cholesterol 0.1 0.1 1.2 -0.0 0.2 -0.1 -0.2 -0.0 0.0 -0.3 -0.7 -0.0 1.1 -0.4 0.3 0.5 0.3 0.4 -0.2 0.1 0.0 -0.0 0.2 0.2 -0.2 -0.1 0.2 0.1 -0.1 -0.2 0.0 0.5 0.1 -0.2 -0.4 -0.4
Lupus 1.6 2.4 12.2 1.8 2.6 0.3 2.4 3.5 -1.3 -1.2 -0.7 1.7 1.6 1.5 0.8 2.4 -0.5 -0.7 -0.9 -0.7 -0.3 -1.1 -0.6 -0.7 0.2 -1.7 3.5 -0.5 -1.1 -1.5 -1.9 0.6 -0.1 -2.0 -1.1 -0.8
Neuroticism (2016) 3.5 5.0 8.7 2.4 2.0 -2.4 2.1 2.5 -2.4 -2.4 -2.5 2.4 0.1 -0.9 2.7 2.6 1.4 0.9 -2.4 -2.4 -2.4 -2.4 -1.7 -2.4 -2.1 -2.9 2.4 -2.1 -2.4 -2.1 -2.7 -1.6 -1.8 -2.7 -2.6 -2.4
Primary Biliary Cirrhosis 2.1 3.1 11.0 1.0 -0.9 -1.9 1.4 0.3 -1.4 -1.9 -2.0 1.2 0.8 -0.3 2.0 1.1 3.3 3.3 -2.2 -1.7 -1.5 -1.7 -1.5 -1.2 -2.3 -1.5 0.5 -2.1 -2.0 -2.0 -1.5 -0.3 -1.5 -1.5 -2.1 -2.5
Rheumatoid Arthritis 1.2 1.6 10.6 0.2 1.6 1.9 0.8 0.9 0.3 0.9 1.6 -0.1 0.1 0.2 -2.0 -1.4 -2.8 -3.3 1.2 0.9 0.8 0.7 0.5 0.8 1.9 0.7 1.0 1.1 0.9 0.8 0.7 0.4 1.1 0.1 1.2 1.5
Schizophrenia (2014) 5.1 11.2 25.7 2.4 -1.0 -3.6 1.5 0.1 -3.1 -3.6 -3.2 2.7 -2.6 -2.9 3.3 1.6 5.1 4.5 -4.0 -3.7 -3.4 -3.5 -3.6 -3.6 -4.4 -3.2 -0.3 -4.1 -4.0 -3.4 -3.1 -3.0 -4.3 -3.0 -3.7 -4.5
Triglycerides 0.4 0.7 2.1 -1.0 -1.0 0.9 -0.5 -1.0 0.9 0.6 0.8 -1.0 0.6 1.0 -0.9 -1.5 -0.1 0.0 1.0 0.6 0.8 0.9 0.5 0.7 0.6 0.8 -1.0 0.8 0.7 0.5 0.8 0.6 0.7 1.0 0.8 0.9
Type 2 Diabetes (T2D) (2012) 0.2 0.2 1.2 0.6 0.2 -0.2 0.5 0.6 -0.6 -0.4 -0.3 0.6 1.0 0.6 0.1 1.1 0.0 0.0 -0.4 0.0 -0.3 -0.6 -0.2 0.2 -0.1 0.1 0.6 -0.2 -0.4 -0.4 -0.1 0.4 0.0 -0.7 -0.4 -0.5
Ulcerative Colitis 1.4 2.0 4.4 1.3 0.7 -1.5 0.9 1.0 -1.5 -1.7 -2.1 1.3 0.2 -1.9 1.6 1.4 1.5 1.0 -1.5 -1.5 -1.2 -1.4 -1.8 -1.0 -1.4 -1.0 0.9 -1.8 -1.6 -2.0 -1.5 -0.6 -0.9 -1.6 -1.7 -1.6
Blood Eosinophil Count 2.1 15.8 30.8 -3.3 -0.4 4.7 -0.2 -1.7 3.7 3.9 3.6 -3.6 5.6 1.6 -5.0 -4.5 -4.4 -3.7 4.3 4.7 3.7 3.9 3.8 5.3 4.1 4.8 -1.4 4.8 4.3 2.8 4.5 4.4 5.5 3.6 3.7 4.4
Blood Platelet Count 0.0 0.1 1.2 0.3 0.1 -0.3 0.3 -0.0 -0.4 -0.1 -0.1 0.3 -1.1 0.4 -0.1 -0.3 0.3 0.2 -0.2 -0.3 -0.2 -0.3 -0.4 -0.2 -0.1 0.1 -0.5 -0.2 -0.2 -0.3 -0.1 -0.6 -0.6 0.2 0.1 0.2
Blood Red Count 0.5 4.4 15.0 -2.3 -2.3 1.7 -1.5 -0.8 2.2 1.7 1.4 -2.0 3.9 2.7 -1.5 -0.4 0.3 1.8 1.5 2.5 2.0 1.9 3.5 2.3 1.0 1.5 -0.5 2.7 1.9 2.8 2.1 3.3 1.8 2.8 1.6 1.3
Blood White Count 1.0 7.5 49.2 -2.3 -5.6 -3.0 -1.7 -5.0 0.8 -0.7 -1.8 -1.7 1.4 -2.2 1.7 -1.5 6.5 7.0 -1.2 -1.1 -1.1 0.0 -0.6 -0.2 -3.9 0.3 -5.5 -0.5 -1.1 -1.5 0.2 0.3 -1.1 1.8 -1.5 -2.3
Heel T-Score 0.9 7.5 63.0 -2.1 -1.9 2.2 -2.3 -0.1 1.9 2.2 2.7 -1.8 7.9 -0.1 -1.3 0.8 -1.0 0.9 1.7 3.8 1.4 1.7 4.5 4.0 0.9 2.4 -0.1 3.5 2.5 2.4 3.1 3.8 4.2 3.1 0.6 1.6
BMI 0.9 5.2 25.0 2.9 4.9 -1.1 2.4 5.0 -2.1 -1.6 -3.1 2.4 1.1 -0.2 1.5 3.0 -1.9 -3.5 -0.6 -1.5 -0.6 -1.5 -1.5 -0.8 0.9 -1.8 4.9 -1.5 -0.9 -2.4 -2.7 -0.2 1.3 -1.9 -1.2 0.4
Height 0.3 6.0 14.1 -1.3 0.2 2.8 -0.8 1.9 2.0 2.7 3.3 -1.4 0.8 3.8 -2.1 -0.0 -3.1 -2.0 2.5 3.0 3.4 2.1 3.7 2.1 3.7 1.5 2.5 2.2 2.9 3.7 1.6 2.7 1.9 1.4 2.7 2.6
Waist Hip Ratio (WHR) 0.9 4.2 13.1 -1.9 -0.9 2.3 -0.1 -2.0 2.0 2.4 2.7 -2.0 0.1 -0.4 -2.3 -3.6 -2.4 -2.2 2.4 1.9 1.6 2.2 1.7 1.8 1.9 2.2 -1.7 2.3 2.1 2.2 2.4 0.8 1.9 2.3 2.1 2.5
Systolic Blood Pressure 0.2 1.1 5.2 0.5 -0.3 -0.8 1.1 -0.6 -0.8 -1.2 -1.2 0.6 1.9 -2.3 0.8 -1.1 1.6 1.3 -1.2 -0.7 -1.3 -1.0 -0.6 -0.2 -1.6 -0.5 -0.5 -0.2 -1.1 -1.4 -0.5 -0.0 -0.0 -0.7 -1.6 -1.4
Smoking Status 1.7 4.1 10.0 1.8 0.9 -2.6 0.9 1.2 -2.1 -2.4 -2.6 1.8 -0.9 -1.1 2.8 2.1 2.6 1.5 -2.1 -2.6 -2.0 -2.1 -2.4 -2.0 -2.3 -1.9 1.1 -3.2 -2.2 -2.3 -2.3 -1.1 -1.6 -1.6 -2.1 -2.2
Allergy or Eczema 8.7 22.8 38.9 -4.2 -1.3 6.2 -2.4 -2.4 4.8 5.3 6.1 -4.4 0.7 3.6 -6.2 -4.2 -5.6 -4.3 5.5 5.6 5.4 5.1 5.1 4.7 5.6 5.2 -1.6 4.9 5.4 6.1 5.2 3.7 3.9 4.6 5.8 5.4
Cardiovascular Disease 1.0 3.2 6.1 2.2 2.0 -1.8 1.5 1.9 -2.1 -2.1 -2.5 2.1 0.9 -1.6 1.9 0.9 0.7 -0.1 -1.9 -2.0 -2.2 -2.0 -1.7 -1.5 -1.8 -2.0 1.7 -1.3 -1.9 -2.2 -2.0 -1.3 -0.5 -1.8 -2.4 -1.4
Hypothyroidism (self reported) 2.9 6.6 15.6 1.7 0.4 -2.8 0.6 0.0 -2.2 -3.0 -3.0 1.8 -0.7 -2.9 3.2 0.3 4.0 2.6 -2.6 -3.6 -2.6 -2.4 -2.8 -3.2 -3.5 -3.2 -0.3 -2.2 -3.0 -3.4 -3.6 -1.8 -2.5 -1.7 -2.7 -2.9
Respiratory disease 1.8 4.1 8.1 -2.3 -0.6 1.7 -1.8 -1.2 2.4 2.2 1.3 -2.5 0.2 1.6 -1.9 -2.4 -1.3 -1.5 2.7 1.7 2.3 2.5 1.3 1.9 2.1 2.4 -1.8 2.1 2.1 1.8 1.9 2.3 2.0 2.6 2.8 2.5
Type 2 Diabetes (T2D) (2018) 0.3 0.5 1.8 0.3 0.1 -0.9 -0.3 0.1 -0.5 -0.7 -1.0 0.3 0.9 -0.1 1.2 0.2 1.0 0.4 -0.6 -1.0 -1.0 -0.5 -0.6 -0.5 -1.0 -0.9 -0.1 -0.3 -0.7 -1.2 -0.8 -0.5 0.3 -0.6 -1.4 -0.7
Lung FEV1/FVC ratio 0.5 2.8 8.6 -1.8 -1.0 1.5 -0.4 -0.8 2.1 2.0 2.0 -1.8 -0.7 1.6 -1.8 -1.2 -1.8 -1.0 1.9 1.9 1.8 1.9 2.3 1.4 1.8 1.5 -0.5 1.6 2.0 2.9 2.0 0.6 1.0 1.5 1.8 1.7
Lung FVC 1.8 9.2 15.2 3.0 1.6 -3.5 1.5 1.6 -3.3 -3.5 -3.6 3.1 -2.2 -1.1 3.9 2.9 3.3 2.3 -3.3 -3.9 -3.5 -3.4 -3.4 -3.7 -3.5 -3.5 0.6 -2.7 -3.5 -3.1 -3.6 -2.4 -3.5 -2.6 -2.7 -3.1
Neuroticism 0.4 1.0 2.4 1.1 0.9 -1.1 1.6 0.7 -1.1 -1.0 -1.0 1.1 -0.4 0.1 1.0 0.2 0.7 0.4 -1.1 -1.1 -0.9 -1.1 -0.6 -1.3 -0.7 -1.5 1.2 -0.9 -1.0 -0.8 -1.3 -0.7 -1.0 -1.1 -0.9 -0.9
Chronotype (morning person) 0.7 1.6 4.0 -1.3 -0.7 1.7 -1.6 -0.5 1.4 1.4 1.4 -1.3 1.4 -0.3 -1.2 -1.7 -1.5 -1.1 1.6 1.1 1.0 1.5 1.0 1.3 1.3 1.0 -0.2 1.5 1.4 0.8 0.9 0.9 2.0 1.3 1.1 1.8
Hair Pigment 0.0 0.7 4.4 -0.5 -2.1 -0.4 -0.2 -1.4 0.1 -0.2 0.2 -0.2 -0.5 -2.1 0.3 -0.1 1.0 1.4 -0.4 0.2 -0.6 -0.1 -0.1 -0.2 -1.2 0.3 -1.9 -0.4 -0.3 0.2 0.8 -1.0 -0.7 0.5 -0.6 -0.9
Tanning 0.2 2.4 21.4 -1.7 -1.5 0.5 -2.0 -1.0 1.4 1.0 0.3 -1.6 4.6 0.7 -0.6 -1.8 1.7 2.0 0.7 0.6 0.8 1.2 1.2 1.8 0.2 0.7 -0.7 1.8 0.8 -0.5 0.3 2.9 2.4 1.3 0.4 0.6
Hand grip strength (left) 0.3 0.8 3.9 -0.6 0.4 1.4 0.3 0.2 0.7 0.7 1.1 -0.6 2.0 0.1 -1.0 -1.7 -0.5 -0.6 0.8 0.5 0.8 0.7 1.0 0.6 0.9 -0.1 0.3 1.5 1.0 -0.1 -0.1 1.1 1.3 1.1 0.6 1.3
Number of treatments/medications taken 0.9 1.6 3.4 1.4 1.0 -1.3 1.4 0.5 -1.4 -1.5 -1.4 1.3 -0.1 -0.3 1.4 0.4 0.9 0.2 -1.3 -1.6 -1.9 -1.4 -1.8 -1.1 -1.6 -1.1 0.1 -1.1 -1.6 -1.6 -1.2 -1.1 -0.8 -1.4 -1.6 -1.4
Average weekly spirits intake 0.3 0.4 1.5 0.8 0.4 -0.8 0.1 0.6 -0.8 -0.5 -0.4 0.9 -0.6 0.1 0.3 1.2 0.2 0.5 -0.8 -0.2 -0.5 -0.8 -0.3 -0.5 -0.4 -0.5 0.8 -1.2 -0.4 -0.4 -0.3 -0.8 -0.8 -0.6 -0.6 -0.7
Sensitivity / hurt feelings 0.6 1.0 4.6 -0.3 0.9 1.2 0.8 0.6 0.6 0.8 1.0 -0.4 0.3 2.1 -1.1 -0.2 -1.4 -1.4 0.8 1.0 1.2 0.7 1.2 0.7 1.6 0.4 1.3 0.7 1.1 1.1 0.5 1.0 0.7 0.5 1.1 1.1
Frequency of depressed mood in last 2 weeks 5.7 8.0 14.8 3.8 3.4 -2.5 3.2 3.4 -3.6 -3.0 -2.7 3.7 -1.6 -0.3 3.0 3.2 0.4 -0.6 -2.9 -2.8 -2.8 -3.4 -2.6 -2.8 -1.7 -3.0 3.7 -3.3 -2.6 -2.5 -3.1 -2.5 -2.2 -3.4 -2.7 -2.2
Hearing difficulty/problems: Yes 0.4 0.7 1.6 -0.9 -1.1 0.9 -1.3 -0.5 1.0 0.8 0.8 -0.9 0.5 0.5 -0.5 -1.3 -0.3 -0.4 1.0 0.6 0.8 1.0 0.6 0.7 0.7 0.7 -0.3 0.9 0.6 1.0 0.6 1.2 0.8 0.7 0.9 0.7
Relative age of first facial hair 0.3 0.7 4.6 -1.1 -2.1 -0.2 -1.2 -1.6 0.9 0.9 1.0 -1.0 0.1 0.6 -0.3 -1.2 0.6 1.0 0.5 0.6 0.6 0.7 0.6 0.5 -0.0 0.7 -1.0 0.3 0.4 0.9 0.6 0.5 0.1 0.6 0.4 -0.1
Other serious medical condition/disability diagnosed by doctor 1.0 1.3 2.7 1.1 0.9 -1.4 0.7 0.8 -1.0 -1.3 -1.6 1.0 -0.6 -0.5 1.4 0.9 0.5 -0.2 -1.0 -1.3 -1.4 -1.0 -1.3 -1.2 -1.2 -1.4 0.5 -0.9 -1.3 -1.2 -1.2 -1.3 -0.7 -1.4 -1.6 -1.2
Ever used hormone-replacement therapy (HRT) 0.8 1.0 9.3 1.0 1.6 -0.9 0.5 0.7 -0.7 -0.4 -0.9 0.8 -3.0 0.3 0.8 0.8 -0.7 -1.4 -0.2 -1.0 -0.6 -0.5 -1.2 -1.4 0.1 -0.8 0.5 -0.9 -0.6 -0.1 -0.9 -1.4 -1.1 -0.6 0.2 0.2
Ever had hysterectomy (womb removed) 1.0 1.1 2.7 0.6 -0.7 -1.4 0.4 -1.1 -0.9 -1.1 -1.0 0.6 -0.6 -0.6 0.9 0.1 1.3 0.6 -1.0 -1.3 -1.5 -0.9 -1.6 -1.0 -1.6 -0.7 -1.2 -0.9 -1.3 -1.4 -0.7 -1.2 -0.9 -0.8 -1.1 -1.3
Systolic blood pressure, automated reading 0.2 0.6 4.4 0.1 -0.4 -0.3 1.0 -0.4 -0.3 -0.6 -0.6 0.2 2.1 -1.7 0.4 -0.7 1.3 1.2 -0.7 -0.3 -0.7 -0.5 0.0 0.1 -1.1 -0.4 -0.4 0.3 -0.7 -0.8 -0.4 0.3 0.2 -0.4 -1.2 -1.0
Eye problems/disorders: Diabetes related eye disease 0.2 0.2 2.0 0.2 1.0 0.2 -0.2 0.1 -0.1 0.1 -0.2 0.1 0.8 1.4 -0.1 0.2 -0.3 -0.3 -0.0 0.2 0.2 -0.0 0.7 0.2 0.5 -0.3 1.1 0.3 0.4 0.1 0.0 0.3 0.5 -0.2 -0.3 0.2
Angina 0.9 1.2 3.5 -0.9 0.2 1.1 0.5 -0.3 1.1 1.3 1.2 -1.0 0.6 0.6 -1.4 -1.3 -1.7 -1.9 1.4 1.0 0.8 1.2 0.9 0.9 1.2 0.8 -0.5 1.4 1.1 1.2 1.1 0.4 1.4 1.0 1.0 1.4
Medication for hormone replacement therapy 1.4 1.6 3.6 -1.2 -0.1 0.6 -1.0 -1.3 1.3 1.6 1.0 -1.3 -1.9 1.4 -1.1 -1.0 -1.6 -1.6 1.5 1.1 1.2 1.4 0.5 0.9 1.5 1.5 -1.2 0.8 1.3 1.5 1.5 0.0 0.6 1.0 1.6 1.5
Vitamin and mineral supplements 0.3 0.3 1.8 0.1 0.9 0.1 0.1 0.6 0.1 0.3 -0.4 0.0 1.3 -0.1 -0.3 -0.0 -1.3 -1.4 0.4 0.5 0.0 0.2 0.5 0.4 0.6 -0.0 0.5 1.0 0.5 -0.1 0.2 0.0 1.1 0.4 0.0 0.8
Supplements: Zinc 0.4 0.5 3.2 -0.3 -0.9 -0.2 -1.0 -0.7 0.0 -0.5 -0.4 -0.2 0.5 -0.7 0.5 -0.4 1.8 1.3 -0.3 -0.7 -0.2 -0.1 -0.8 -0.3 -0.9 -0.3 -1.0 -0.2 -0.7 -1.1 -0.6 0.5 -0.3 -0.2 -0.4 -0.9
Medication: Co-codamol 1.2 1.4 3.0 1.2 0.7 -1.0 1.0 0.0 -1.4 -1.3 -0.5 1.3 -0.8 -1.1 0.8 0.5 0.7 0.3 -1.4 -1.2 -1.7 -1.4 -1.2 -1.4 -1.6 -1.3 -0.1 -0.7 -1.4 -1.2 -1.1 -1.7 -1.3 -1.5 -1.6 -1.5
Medication: Metformin 1.3 1.8 3.6 1.2 0.6 -1.9 0.9 0.5 -1.4 -1.4 -1.9 1.3 -0.3 -0.6 1.9 1.1 1.3 0.8 -1.5 -1.7 -1.5 -1.4 -1.5 -1.3 -1.5 -1.5 0.6 -1.5 -1.5 -1.8 -1.4 -1.2 -0.8 -1.3 -1.8 -1.3
Diabetes (father) 0.1 0.1 0.7 0.1 0.1 -0.5 -0.2 0.2 -0.0 -0.2 -0.7 0.1 0.6 -0.4 0.0 0.4 0.2 0.1 -0.2 0.2 0.2 -0.1 0.1 0.3 0.1 -0.1 0.3 0.1 0.0 -0.8 -0.3 0.2 0.3 -0.2 -0.4 -0.2
Diabetes (mother) 0.4 0.6 2.8 0.7 0.3 -0.4 0.5 1.4 -0.6 -0.7 -0.8 0.7 1.4 -0.2 1.0 1.0 0.1 -0.3 -0.4 -0.4 -0.3 -0.5 -0.1 -0.2 -0.3 -0.9 1.7 -0.2 -0.6 -0.6 -0.9 0.6 0.4 -1.0 -1.1 -0.7
Severe depression (siblings) 1.4 1.6 3.2 1.6 1.7 -1.5 1.6 1.2 -1.4 -1.3 -1.7 1.4 -1.6 -0.5 1.4 1.0 -0.1 -1.0 -0.9 -1.4 -1.4 -1.2 -1.8 -1.2 -0.8 -1.0 0.6 -1.1 -1.3 -1.2 -1.1 -1.3 -0.9 -1.3 -1.0 -0.7
Pack years adult smoking proportion 0.3 0.4 1.3 0.3 0.0 -0.8 0.3 -0.2 -0.4 -0.5 -0.8 0.3 -0.8 -1.1 0.4 0.1 0.8 0.2 -0.4 -0.8 -0.4 -0.3 -0.9 -0.9 -0.6 -0.9 -0.4 -0.6 -0.6 -1.1 -0.9 -0.8 -0.7 0.1 -0.3 -0.3
Impedance of leg (right) 1.5 7.3 24.6 -3.7 -5.0 2.1 -4.1 -4.3 3.0 2.1 2.8 -3.4 2.3 1.1 -1.8 -3.7 2.3 3.3 1.7 2.0 2.2 2.5 2.1 2.3 0.1 2.7 -4.0 2.0 1.7 2.0 2.6 3.0 1.1 3.0 2.0 0.5
Leg fat-free mass (left) 1.2 6.5 37.5 3.2 5.5 -0.2 3.5 5.9 -2.1 -1.0 -1.7 2.7 -0.3 0.2 1.0 3.3 -3.8 -4.8 -0.2 -0.7 -0.2 -1.4 -0.4 -0.7 2.0 -1.7 6.1 -1.1 -0.2 -0.7 -1.9 -0.5 0.9 -2.0 -0.5 1.1
Trunk fat percentage 0.5 1.8 6.7 1.3 1.2 -1.7 0.5 2.1 -1.3 -1.5 -2.6 1.2 0.6 -0.4 2.1 1.8 1.2 0.5 -1.1 -1.4 -0.5 -1.2 -1.1 -0.8 -0.7 -1.3 2.2 -1.7 -1.1 -1.7 -1.9 0.4 -0.2 -1.1 -1.2 -1.0
Hand grip strength (right) 0.8 2.0 5.5 -0.8 1.0 2.1 0.5 0.2 1.1 1.4 1.8 -1.0 1.9 0.4 -1.7 -2.2 -1.8 -2.1 1.6 0.9 1.1 1.3 1.2 1.1 1.7 0.5 0.2 2.0 1.6 0.4 0.4 1.0 2.3 1.6 1.2 2.4
Townsend deprivation index at recruitment 1.0 1.4 3.2 1.1 0.6 -1.7 0.3 0.1 -1.1 -1.3 -1.8 1.0 -1.3 -1.5 1.2 0.2 1.0 -0.1 -0.8 -1.8 -1.2 -1.0 -1.8 -1.6 -1.1 -1.4 0.2 -1.4 -1.1 -1.7 -1.7 -1.3 -1.0 -0.6 -0.9 -0.6
Current tobacco smoking 0.8 1.3 4.8 0.6 -0.4 -1.3 0.3 -0.5 -0.8 -1.3 -1.2 0.6 -1.1 -0.7 1.3 0.7 2.2 1.5 -1.1 -1.5 -0.8 -0.9 -1.3 -1.3 -1.4 -1.0 0.0 -2.0 -1.1 -1.0 -1.2 -0.6 -1.2 -0.5 -0.9 -1.3
Average weekly fortified wine intake 0.4 0.5 2.1 0.0 0.5 1.0 0.1 0.8 0.2 0.5 1.0 0.1 0.7 1.1 -0.6 0.8 -1.1 -0.5 0.4 1.0 0.5 0.2 1.4 0.3 0.7 -0.2 1.0 0.9 0.6 1.2 0.5 0.5 0.2 0.3 0.4 0.4
Maternal smoking around birth 0.4 0.6 2.5 -0.7 -0.3 0.4 -1.2 -0.3 0.7 0.6 -0.0 -0.8 1.6 0.4 -0.5 -0.3 0.1 0.0 0.7 0.8 0.9 0.7 0.9 1.1 0.7 0.7 0.1 0.7 0.8 0.4 0.6 1.6 1.1 1.1 0.7 0.8
Fed-up feelings 0.1 0.1 0.7 0.2 0.7 -0.6 0.5 0.2 -0.1 0.0 -0.3 0.1 -0.6 0.1 0.3 -0.2 -0.3 -0.8 0.1 -0.4 -0.1 -0.0 -0.1 -0.4 0.2 -0.5 0.6 -0.5 0.1 0.1 -0.4 -0.6 0.1 -0.1 -0.1 0.2
Frequency of unenthusiasm / disinterest in last 2 weeks 2.0 2.7 6.1 2.3 2.5 -1.6 1.6 2.0 -2.1 -1.7 -1.7 2.1 -0.7 -0.7 1.4 1.6 -0.1 -0.9 -1.5 -1.8 -1.7 -1.9 -1.7 -1.5 -0.8 -1.7 2.1 -1.8 -1.4 -1.5 -1.9 -1.4 -0.8 -2.0 -1.5 -1.0
Relative age voice broke 0.5 0.8 6.9 -1.1 -2.6 -0.3 -1.4 -1.9 0.8 0.6 0.9 -0.9 0.5 -0.6 0.0 -1.0 1.1 1.4 0.4 0.4 0.3 0.6 0.5 0.4 -0.5 0.6 -1.5 0.1 0.3 0.7 0.6 0.2 0.2 1.1 0.0 -0.1
Taking other prescription medications 2.4 3.6 7.2 1.6 0.5 -2.5 0.6 -0.1 -1.8 -2.2 -2.7 1.6 -1.5 -1.7 2.2 0.6 1.9 1.0 -1.9 -2.4 -2.6 -1.9 -2.5 -2.3 -2.5 -2.1 -0.6 -1.6 -2.4 -2.1 -2.0 -2.1 -1.9 -1.5 -2.1 -2.0
Age when periods started (menarche) 1.0 2.4 10.5 -2.0 -3.0 0.1 -1.8 -2.7 1.5 1.2 1.1 -1.8 1.4 -1.6 -0.8 -2.2 1.1 1.9 0.8 1.1 0.5 1.2 1.0 1.5 -0.4 2.0 -3.2 1.4 0.8 1.0 1.8 1.1 0.6 1.7 0.8 0.3
Bilateral oophorectomy (both ovaries removed) 0.2 0.2 1.9 0.3 0.5 0.0 0.8 0.3 -0.1 0.1 0.3 0.2 -1.4 0.3 0.2 0.4 -0.8 -1.0 0.1 -0.0 -0.3 -0.0 -0.1 -0.4 0.2 -0.0 -0.1 0.1 -0.0 0.8 0.3 -0.8 -0.5 -0.2 0.4 0.2
Heel bone mineral density (BMD) T-score, automated (left) 1.5 3.5 15.0 -0.7 0.2 2.3 0.3 0.5 1.0 1.8 2.6 -0.6 3.9 0.8 -1.9 -0.1 -2.6 -1.4 1.1 2.8 1.2 1.0 3.0 2.7 1.7 1.8 1.3 1.8 2.2 2.0 2.4 1.5 2.9 1.2 0.6 1.6
Tinnitus: Yes, but not now, but have in the past 0.2 0.3 1.6 -0.0 0.5 -0.5 0.7 -0.1 0.2 0.4 0.1 -0.1 -1.2 0.1 -0.3 -0.7 -1.3 -1.2 0.3 0.3 0.0 0.2 -0.1 0.2 0.5 0.5 -0.2 0.0 0.3 0.5 0.6 -0.8 0.0 -0.4 0.2 0.3
Qualifications: CSEs or equivalent 0.4 0.5 3.0 0.5 1.6 0.5 0.3 0.9 -0.1 0.1 -0.2 0.4 0.5 1.4 -0.7 -0.0 -1.3 -1.6 0.3 0.3 0.4 0.0 0.6 -0.1 1.0 -0.7 1.7 0.4 0.5 -0.2 -0.6 -0.1 0.6 -0.2 0.0 0.7
Serious illness, injury or assault to yourself 0.5 0.6 3.3 0.8 1.4 -0.3 1.0 1.4 -0.5 -0.3 -0.9 0.6 0.1 1.2 0.5 0.5 -0.9 -1.3 -0.0 -0.6 -0.2 -0.3 -0.7 -0.3 0.5 -0.7 1.8 -0.5 -0.2 -1.0 -1.0 -0.1 0.6 -0.7 -0.3 0.4
High blood pressure 0.3 0.8 1.9 1.1 0.9 -0.9 1.4 0.8 -1.1 -1.0 -1.3 1.1 0.5 -0.9 0.8 0.1 0.3 0.1 -1.0 -0.9 -1.2 -1.0 -0.8 -0.7 -0.9 -0.9 0.8 -0.7 -0.9 -0.9 -0.9 -0.8 -0.2 -0.7 -1.2 -0.6
Hayfever, allergic rhinitis or eczema 11.4 24.7 41.6 -4.5 -1.6 6.5 -2.7 -2.5 5.1 5.5 6.2 -4.7 1.3 3.3 -6.2 -4.3 -5.3 -3.8 5.7 6.0 5.7 5.3 5.6 5.0 5.7 5.3 -1.9 5.3 5.7 6.1 5.4 4.1 4.0 5.4 6.0 5.7
Multivitamins +/- minerals 0.4 0.5 2.9 0.0 -1.2 -0.5 -0.3 -0.8 -0.2 -0.4 0.1 0.1 -1.7 0.1 0.5 0.0 1.3 1.4 -0.6 -0.5 -0.2 -0.3 -0.9 -0.4 -0.7 0.3 -0.9 -1.1 -0.7 -0.0 0.0 -0.2 -1.4 -0.5 -0.0 -1.0
Stomach or abdominal pain in last month 0.1 0.2 1.3 0.4 0.7 0.5 0.3 0.1 -0.2 0.0 0.7 0.3 -0.3 0.2 -0.3 -0.6 -0.6 -1.1 0.2 -0.2 -0.0 -0.0 0.0 -0.6 0.3 -0.7 0.7 -0.0 0.1 0.1 -0.5 -0.5 -0.1 -0.0 0.1 0.4
Supplements: Glucosamine 0.2 0.2 1.6 -0.1 0.1 1.0 -0.8 0.0 0.1 0.3 0.9 -0.1 0.6 1.3 -0.5 -0.1 -0.3 -0.2 0.2 0.4 0.4 0.2 0.4 0.4 0.4 0.4 0.4 0.1 0.4 0.3 0.1 0.6 0.5 -0.1 0.2 0.1
Diverticular disease/diverticulitis (self-reported) 0.2 0.2 1.2 0.6 0.3 -1.0 0.7 0.2 -0.7 -0.2 -0.6 0.7 -0.7 0.1 0.3 0.1 -0.4 -0.2 -0.5 -0.3 -0.7 -0.6 -0.4 -0.4 -0.2 -0.3 0.1 -0.3 -0.4 -0.1 -0.0 -1.1 -0.5 -0.6 -0.4 -0.2
Medication: Atenolol 0.1 0.1 0.7 0.1 -0.6 -0.0 0.2 -0.1 -0.2 -0.1 0.5 0.1 0.8 -0.4 -0.7 -0.2 -0.0 0.2 -0.4 0.3 -0.4 -0.3 -0.2 0.3 -0.6 0.5 -0.4 -0.3 -0.3 -0.0 0.6 -0.1 -0.2 -0.1 -0.4 -0.5
Medication: Levothyroxine sodium 4.9 8.4 14.9 2.3 1.2 -3.3 1.4 0.2 -2.7 -3.2 -3.1 2.4 -1.7 -3.5 3.5 0.9 3.4 2.1 -3.0 -3.9 -3.4 -2.8 -2.9 -3.8 -3.7 -3.8 0.1 -2.2 -3.3 -3.2 -3.8 -2.8 -3.0 -2.5 -3.2 -3.2
Sitting height 0.4 3.0 23.0 1.5 2.8 1.5 2.1 4.3 -0.7 0.0 0.6 1.3 1.2 2.4 -0.1 1.9 -2.6 -2.6 0.2 0.7 0.9 -0.3 1.2 0.5 1.9 -0.4 4.8 -0.2 0.7 0.9 -0.4 1.3 1.2 -1.2 0.3 0.7
Chronic bronchitis/emphysema (father) 0.4 0.4 1.2 0.4 -0.6 -0.6 0.4 -0.4 -0.6 -0.9 -1.0 0.4 -0.0 -1.0 0.7 0.2 1.1 0.9 -0.7 -0.6 -0.8 -0.7 -0.7 -0.2 -1.1 -0.1 -0.5 -0.7 -0.8 -0.6 -0.2 -0.2 -0.4 0.0 -0.7 -0.7
High blood pressure (mother) 1.0 1.3 3.6 -1.2 -0.8 1.0 -0.6 -0.6 1.2 1.3 1.3 -1.1 1.9 0.6 -1.5 -1.7 -1.0 -0.3 1.0 1.4 0.8 1.1 1.4 1.6 0.9 1.2 -0.4 1.5 1.2 1.0 1.3 1.1 1.6 0.9 0.7 1.0
Body mass index (BMI) 1.2 5.0 16.3 2.9 4.0 -1.9 2.3 3.9 -2.4 -2.1 -3.2 2.6 -0.1 -0.9 2.1 2.7 -0.7 -2.3 -1.4 -2.2 -1.5 -2.0 -2.1 -1.7 -0.3 -2.3 3.7 -1.9 -1.6 -2.7 -3.0 -1.2 0.0 -2.2 -1.8 -0.5
Impedance of leg (left) 1.0 4.7 18.4 -3.0 -4.3 1.3 -3.3 -3.8 2.4 1.5 2.2 -2.8 2.0 0.8 -1.2 -3.0 2.5 3.3 1.0 1.2 1.4 1.9 1.4 1.6 -0.4 1.9 -3.6 1.4 1.1 1.1 1.8 2.2 0.7 2.2 1.2 0.0
Leg predicted mass (left) 1.2 6.5 38.0 3.2 5.5 -0.2 3.5 5.9 -2.1 -1.0 -1.7 2.7 -0.3 0.3 1.0 3.3 -3.8 -4.8 -0.2 -0.7 -0.2 -1.4 -0.4 -0.7 2.0 -1.7 6.2 -1.1 -0.1 -0.7 -1.9 -0.5 1.0 -2.0 -0.5 1.1
Trunk fat mass 0.6 2.4 13.0 1.9 2.7 -1.1 1.4 3.5 -1.4 -1.3 -2.3 1.6 0.8 -0.0 1.7 2.2 -0.4 -1.4 -0.6 -1.1 -0.2 -1.1 -0.8 -0.6 0.4 -1.3 3.6 -1.4 -0.7 -1.5 -2.0 0.4 0.6 -1.2 -0.9 -0.1
Waist circumference 0.6 2.2 12.1 1.8 3.4 -0.2 1.8 3.3 -1.1 -0.6 -1.3 1.4 -0.2 -0.1 0.6 1.4 -2.1 -3.4 0.1 -0.6 0.1 -0.6 -0.5 -0.5 1.2 -1.0 3.5 -0.7 -0.1 -0.6 -1.4 -0.0 0.8 -0.9 -0.1 0.8
Number of incorrect matches in round 0.4 0.7 4.6 -0.7 -2.2 -0.5 -1.2 -1.6 0.5 0.4 0.1 -0.6 -0.7 -0.8 -0.3 -0.6 0.4 1.1 0.1 0.7 0.3 0.3 0.4 0.6 -0.1 1.1 -1.7 0.2 0.3 0.9 1.2 -0.1 -0.4 0.9 0.5 0.1
Past tobacco smoking 0.5 0.9 2.6 -0.9 -1.2 1.3 0.3 -1.0 0.9 1.0 1.6 -0.7 0.8 0.6 -1.2 -0.8 -0.8 0.2 0.5 1.5 0.7 0.8 1.5 0.9 0.7 0.7 -0.6 1.5 0.8 1.4 1.4 0.4 0.2 0.2 0.6 0.3
Alcohol usually taken with meals 3.1 5.1 10.6 -1.9 -0.5 3.2 -1.4 -0.4 2.1 2.6 3.2 -1.9 0.3 2.2 -2.6 -1.5 -2.4 -1.3 2.4 2.7 2.5 2.2 2.3 2.5 2.7 2.9 -0.4 1.9 2.5 2.9 2.8 2.2 1.8 2.0 2.9 2.5
Nervous feelings 0.5 1.0 2.7 -0.4 0.6 1.5 0.8 0.6 0.7 1.0 1.6 -0.5 0.7 1.6 -1.2 -0.4 -1.5 -1.3 1.0 1.0 1.0 0.9 1.0 0.7 1.4 0.5 0.7 1.2 0.8 1.3 0.7 1.2 0.7 -0.0 1.1 0.8
Frequency of tenseness / restlessness in last 2 weeks 3.8 5.9 14.9 3.4 3.9 -1.8 3.2 3.5 -3.0 -2.3 -2.1 3.2 -1.3 -0.0 2.0 2.7 -0.3 -1.1 -2.2 -2.5 -2.2 -2.7 -2.6 -2.4 -1.0 -2.6 3.4 -2.4 -2.3 -2.4 -2.7 -2.0 -1.7 -3.0 -1.9 -1.4
Hearing difficulty/problems with background noise 0.0 0.1 0.7 0.1 -0.1 0.3 -0.4 -0.4 -0.1 -0.0 0.0 0.0 -0.1 -0.5 0.1 -0.8 -0.1 -0.2 0.2 -0.0 -0.1 -0.0 -0.0 0.2 0.0 0.3 -0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.2 0.1 0.2
Hair/balding pattern: Pattern 2 0.2 0.3 1.3 0.6 1.0 -0.2 1.0 0.6 -0.4 -0.1 -0.3 0.5 -1.0 0.2 0.1 0.5 -1.0 -1.1 -0.1 -0.1 -0.3 -0.3 -0.5 -0.4 0.2 -0.2 0.6 -0.7 0.1 -0.1 -0.0 -0.8 -0.1 -0.3 0.0 0.3
Had menopause 0.3 0.4 2.6 -0.6 -0.1 0.6 -1.6 0.2 0.7 0.8 0.4 -0.6 0.4 1.0 -0.5 0.1 -0.2 -0.3 0.9 0.3 1.0 0.8 0.4 0.4 0.9 0.2 0.2 0.8 0.4 0.3 -0.1 1.1 0.7 0.4 0.8 0.7
Had other major operations 2.1 2.5 6.2 2.0 1.6 -1.4 1.1 1.4 -1.9 -1.6 -1.7 1.8 -2.5 -0.1 1.7 1.2 0.0 -1.0 -1.2 -2.1 -1.7 -1.6 -2.3 -2.0 -0.9 -1.8 1.0 -1.7 -1.7 -1.4 -1.9 -2.1 -1.4 -1.6 -1.1 -0.8
Forced vital capacity (FVC) 0.3 1.1 7.0 1.5 1.9 -0.5 0.6 2.6 -1.2 -0.9 -0.6 1.5 -0.2 0.7 1.2 2.0 -0.5 -0.6 -0.7 -0.6 -0.6 -1.1 -0.0 -0.8 0.0 -1.1 2.3 -0.6 -0.6 0.0 -1.0 -0.2 -0.6 -0.9 -0.5 -0.3
Heel bone mineral density (BMD) T-score, automated (right) 1.0 2.3 13.0 0.0 1.0 1.8 0.7 1.1 0.3 1.1 2.1 0.1 3.6 0.1 -1.3 0.5 -2.6 -1.7 0.7 2.1 0.4 0.4 2.5 2.0 1.2 1.0 1.7 1.5 1.6 1.6 1.6 0.9 2.5 0.6 0.0 1.2
Ever unenthusiastic/disinterested for a whole week 1.4 1.7 3.4 1.0 0.0 -1.8 0.6 0.1 -1.2 -1.3 -1.6 1.1 -1.2 -0.8 1.6 1.0 1.7 1.5 -1.6 -1.4 -1.4 -1.4 -1.4 -1.4 -1.5 -1.2 0.1 -1.7 -1.3 -1.4 -1.1 -1.4 -1.6 -1.2 -1.3 -1.5
Qualifications: None of the above 0.0 0.1 1.1 -0.1 -0.2 -0.0 0.4 -0.5 0.1 0.3 0.2 -0.1 -0.2 -0.6 -0.4 -1.1 -0.5 -0.5 0.2 0.1 -0.1 0.2 -0.1 0.0 0.1 0.1 -0.4 0.3 0.1 0.2 0.1 -0.3 0.1 -0.4 0.1 -0.0
Financial difficulties in last 2 years 1.2 1.6 6.1 0.7 1.1 -0.8 0.0 0.6 -0.8 -1.3 -1.2 0.8 -0.2 -1.7 1.5 0.5 2.0 1.4 -1.1 -1.7 -0.7 -0.9 -0.9 -1.9 -1.2 -2.5 0.8 -0.7 -1.3 -1.6 -2.3 -0.4 -1.5 -0.9 -1.1 -1.3
Mouth/teeth dental problems 0.6 1.0 1.7 -1.0 -0.3 1.3 -1.2 -0.8 1.0 1.1 1.3 -1.0 -1.0 0.3 -1.0 -1.0 -0.9 -0.8 1.2 1.1 1.2 1.1 0.8 0.5 1.0 0.9 -1.0 0.9 1.0 1.2 1.1 0.1 0.1 1.1 1.3 1.0
Heart attack 0.3 0.4 2.2 0.8 0.9 -0.7 0.5 1.2 -0.7 -0.2 -0.7 0.8 1.4 0.2 0.4 1.2 -0.5 -0.2 -0.5 0.1 -0.3 -0.6 0.5 0.2 -0.1 -0.4 1.5 0.1 -0.2 -0.1 -0.2 0.3 0.4 -0.6 -0.7 -0.3
Allergy 7.0 16.1 26.6 3.5 0.7 -5.2 2.4 1.4 -4.1 -4.4 -4.6 3.7 -1.1 -3.0 4.8 3.5 4.7 3.8 -4.8 -4.7 -4.7 -4.3 -4.2 -3.9 -4.9 -4.2 1.1 -4.2 -4.6 -4.6 -4.1 -3.5 -3.6 -4.4 -5.1 -5.0
Pain all over the body in last month 0.4 0.4 1.4 0.5 -0.2 -0.7 0.3 -0.6 -0.7 -0.6 -0.3 0.6 0.4 0.1 0.8 0.8 0.5 0.6 -1.0 -0.2 -1.0 -0.8 -0.3 -0.2 -1.0 -0.3 -0.2 -0.3 -0.6 -0.6 -0.1 -0.8 -0.5 -1.1 -1.2 -1.2
Diabetes (self-reported) 0.6 0.9 2.9 0.9 1.5 -0.8 0.3 1.5 -0.9 -0.8 -1.3 0.9 1.6 0.5 1.0 1.0 0.2 -0.3 -0.7 -0.9 -0.8 -0.7 -0.3 -0.3 -0.4 -1.1 1.7 -0.3 -0.7 -1.1 -1.1 0.1 0.7 -1.1 -1.3 -0.5
Hayfever/allergic rhinitis (self-reported) 2.8 3.8 7.0 -1.7 -0.7 2.7 -1.1 -1.3 1.8 1.9 2.2 -1.7 0.4 2.5 -2.2 -1.8 -1.7 -0.9 2.1 2.2 2.1 1.9 2.3 1.9 2.1 2.0 -0.8 2.1 2.3 2.3 2.1 1.7 1.5 2.4 2.4 2.4
Medication: Ramipril 0.5 0.6 3.1 1.1 1.8 -0.2 1.5 1.5 -0.8 -0.3 -0.6 1.0 0.2 -0.9 -0.0 0.9 -1.3 -1.6 -0.2 0.1 -0.4 -0.5 -0.1 0.0 0.4 -0.3 1.2 0.0 -0.2 -0.2 -0.1 -0.5 0.3 -0.6 -0.3 0.2
Medication: Simvastatin 2.0 3.0 6.2 2.1 1.2 -2.0 1.8 1.3 -2.1 -1.8 -1.7 2.1 0.3 -1.0 1.6 1.8 0.6 -0.2 -1.8 -1.7 -2.2 -2.0 -1.8 -1.5 -1.7 -1.9 1.3 -1.8 -1.8 -2.3 -1.9 -1.9 -0.6 -2.0 -2.5 -1.6
Fluid intelligence score 0.2 0.3 2.8 -0.5 -1.0 0.4 -1.0 -0.2 0.4 0.2 0.6 -0.5 1.7 -1.0 0.2 -0.0 0.6 0.7 0.2 0.1 -0.0 0.3 0.5 0.3 -0.4 0.0 -0.2 0.2 0.2 0.4 0.1 0.7 0.7 0.8 -0.2 0.1
Illnesses of siblings 0.6 0.9 2.7 -1.1 -1.2 1.1 -0.7 -1.1 1.0 0.9 1.4 -1.0 -1.3 1.6 -0.6 -0.4 0.0 0.5 0.8 0.7 1.0 0.9 0.9 0.3 0.6 0.7 -1.0 0.4 0.9 1.4 0.9 0.2 -0.4 1.2 1.2 0.7
Neuroticism score 0.6 1.2 3.0 1.4 1.4 -1.1 1.7 1.1 -1.3 -1.1 -0.9 1.4 -0.5 0.4 1.1 0.9 0.3 -0.1 -1.2 -1.0 -0.9 -1.2 -0.6 -1.2 -0.6 -1.3 1.6 -1.1 -0.9 -0.6 -1.1 -0.9 -1.0 -1.5 -1.0 -1.0
Weight 0.9 4.4 26.8 2.5 4.6 -0.3 2.4 5.1 -1.6 -0.8 -1.7 2.0 0.5 0.4 1.0 2.7 -2.7 -3.8 -0.1 -0.7 0.0 -1.0 -0.4 -0.4 1.6 -1.4 5.2 -0.9 -0.1 -1.0 -2.0 0.2 1.3 -1.5 -0.4 1.0
Impedance of arm (right) 1.7 8.2 35.6 -3.9 -6.0 1.4 -4.3 -4.3 3.2 2.1 2.5 -3.5 0.5 1.1 -1.5 -3.1 2.8 4.5 1.5 2.4 2.7 2.5 2.5 2.0 0.2 2.8 -4.0 1.3 1.8 3.1 2.9 3.1 -0.3 3.2 2.5 0.2
Arm fat percentage (right) 0.6 2.5 8.1 1.8 1.6 -1.9 0.8 2.4 -1.6 -1.9 -2.9 1.6 0.4 -0.5 2.1 2.0 1.0 0.1 -1.3 -1.7 -0.8 -1.5 -1.4 -1.1 -0.8 -1.6 2.4 -1.8 -1.4 -1.9 -2.2 0.0 -0.3 -1.3 -1.4 -1.0
Trunk fat-free mass 1.2 6.9 37.6 2.4 5.6 1.3 3.2 5.8 -1.1 0.3 0.0 1.8 0.8 1.2 -0.4 2.4 -5.3 -6.1 1.0 0.6 0.8 -0.3 0.7 0.5 3.3 -0.7 6.1 0.3 1.1 0.3 -0.9 0.4 2.5 -1.0 0.6 2.5
Hip circumference 0.6 2.7 18.0 2.1 3.0 -0.8 1.1 4.0 -1.5 -1.2 -2.0 1.8 0.1 0.8 1.4 2.8 -0.7 -1.6 -0.7 -1.0 0.0 -1.2 -0.5 -0.9 0.6 -1.6 4.2 -1.5 -0.7 -0.8 -2.1 0.5 -0.0 -1.6 -0.6 -0.3
Time employed in main current job 0.5 0.6 2.7 1.0 1.7 -0.2 0.9 1.1 -0.8 -0.5 -0.6 0.8 0.6 -0.6 0.4 1.0 -1.2 -1.3 -0.4 -0.4 -0.9 -0.6 -0.7 0.0 -0.0 -0.1 0.8 -0.0 -0.4 -1.0 -0.3 -0.7 0.6 -1.3 -0.8 -0.1
Alcohol intake versus 10 years previously 0.4 0.6 2.2 -0.1 -0.5 -0.8 -0.3 -1.3 -0.2 -0.6 -0.8 0.0 -0.2 -0.7 0.4 -0.8 1.4 1.1 -0.6 -0.7 -0.7 -0.4 -0.8 -0.6 -1.1 -0.5 -1.5 0.1 -0.8 -1.1 -0.6 -0.5 -0.8 -0.3 -0.5 -0.8
Father’s age at death 0.8 1.1 4.7 -1.3 -2.2 0.2 -1.8 -1.5 0.9 0.7 0.9 -1.1 0.6 -0.1 -0.7 -0.8 1.4 2.1 0.1 0.8 0.6 0.6 0.7 1.1 -0.4 1.5 -1.9 0.5 0.3 0.7 1.2 1.2 0.1 0.9 0.5 -0.2
Worrier / anxious feelings 0.1 0.2 1.1 -0.1 0.3 0.3 0.0 -0.6 0.2 0.5 0.6 -0.0 -0.5 0.4 -0.8 -0.5 -1.0 -0.5 0.2 0.6 0.3 0.2 0.6 0.0 0.6 0.1 -0.1 0.7 0.5 0.6 0.6 -0.6 -0.3 0.0 0.5 0.5
Frequency of tiredness / lethargy in last 2 weeks 1.6 2.7 5.6 1.6 1.7 -1.7 1.5 0.6 -1.7 -1.6 -1.5 1.6 -2.0 -1.5 1.6 1.1 0.6 -0.3 -1.5 -2.1 -1.9 -1.6 -2.0 -2.2 -1.4 -2.2 0.6 -1.4 -1.5 -2.0 -2.0 -2.4 -1.6 -1.7 -1.7 -1.2
Falls in the last year 1.1 1.4 3.7 1.5 0.3 -1.5 0.8 1.1 -1.4 -1.1 -1.0 1.6 -1.5 -1.2 1.1 1.4 0.1 0.2 -1.2 -0.8 -1.2 -1.4 -1.1 -1.1 -0.9 -0.8 1.3 -1.9 -1.3 -0.1 -0.7 -1.4 -1.4 -1.8 -1.2 -1.5
Hair/balding pattern: Pattern 3 0.3 0.5 1.4 0.1 -0.6 -1.1 0.4 -0.7 -0.3 -0.6 -1.0 0.1 -1.0 -1.0 0.5 -0.2 1.2 0.7 -0.5 -0.7 -0.5 -0.4 -1.0 -0.4 -0.9 -0.1 -1.0 -0.7 -0.7 -0.9 -0.4 -0.5 -0.8 -0.6 -0.8 -1.0
Number of live births 0.3 0.4 1.7 0.7 0.2 -0.6 0.1 1.0 -0.6 -0.6 -1.0 0.7 -0.1 -1.3 1.2 0.6 0.1 0.2 -0.5 -0.6 -0.5 -0.6 -0.3 -0.5 -0.2 -0.6 1.2 -0.8 -0.4 -0.1 -0.7 -0.2 -0.2 -0.5 -0.5 -0.3
Forced expiratory volume in 1-second (FEV1) 0.4 1.5 8.0 1.7 2.3 -0.1 1.5 2.8 -1.2 -0.8 -0.3 1.6 -1.1 1.0 1.0 1.9 -1.2 -1.4 -0.5 -0.5 -0.5 -1.0 -0.0 -1.0 0.4 -1.2 2.6 -0.6 -0.4 0.3 -1.0 -0.6 -0.8 -1.1 -0.3 -0.1
Pulse rate 1.2 1.9 7.4 1.9 2.7 0.0 2.3 2.2 -1.5 -1.1 -1.0 1.8 -1.0 0.9 1.3 2.1 -1.4 -2.1 -0.6 -0.8 -0.7 -1.1 -0.8 -1.2 0.2 -1.5 2.4 -0.7 -0.8 -0.5 -1.4 -1.0 -0.5 -1.6 -0.8 -0.3
Happiness 1.6 1.9 4.1 1.0 -0.0 -1.8 0.4 0.2 -1.3 -1.5 -1.5 1.2 -0.6 -1.3 1.8 1.8 1.9 1.9 -1.6 -1.3 -1.6 -1.5 -0.9 -1.4 -2.0 -1.4 0.0 -1.4 -1.5 -0.9 -1.2 -1.0 -1.6 -0.9 -1.6 -1.8
Noisy workplace 0.3 0.4 1.6 0.7 0.6 -0.6 0.9 0.8 -0.6 -0.7 -1.0 0.5 0.2 0.7 0.5 0.5 0.3 -0.3 -0.4 -0.6 -0.2 -0.5 -0.7 -0.1 -0.1 -0.3 0.8 -0.8 -0.4 -1.2 -0.6 -0.1 0.2 -0.5 -0.7 -0.2
Qualifications: A levels/AS levels or equivalent 0.1 0.1 0.6 -0.3 -0.4 0.2 -0.4 -0.2 0.2 -0.0 0.4 -0.2 -0.1 -0.8 0.4 0.4 0.6 0.7 0.1 -0.1 -0.0 0.1 0.2 -0.5 -0.5 -0.3 -0.7 0.1 -0.1 0.3 -0.0 -0.2 -0.6 0.8 0.1 -0.0
Serious illness, injury or assault of a close relative in last 2 years 0.6 0.7 1.7 -0.5 0.2 0.9 0.8 0.0 0.6 0.9 0.8 -0.6 -0.0 0.3 -1.2 -0.0 -1.1 -1.0 1.0 0.8 0.8 0.8 0.7 0.9 1.1 1.0 -0.2 1.0 0.9 0.8 0.8 0.6 1.0 0.9 1.1 1.3
Mouth/teeth dental problems: Dentures 0.4 0.7 4.5 0.5 0.6 0.0 0.5 1.9 -0.4 -0.5 -0.8 0.5 2.1 0.6 0.5 0.8 0.4 0.1 -0.3 -0.5 -0.0 -0.3 -0.1 0.1 0.1 -0.7 1.9 -0.1 -0.5 -0.7 -1.1 1.4 0.8 -0.8 -0.6 -0.4
Asthma 1.5 2.9 6.3 -1.4 0.4 1.8 -1.1 -0.2 1.7 1.7 1.3 -1.7 0.9 1.6 -1.6 -2.0 -1.9 -2.2 2.3 1.4 1.8 2.0 1.3 1.6 2.2 1.5 -0.3 2.0 1.9 1.3 1.2 2.1 2.3 2.0 2.3 2.5
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 2.1 0.5 0.6 -0.7 0.5 0.1 -0.6 -0.8 -1.2 0.5 1.3 0.3 0.9 0.1 1.2 0.9 -0.8 -0.8 -0.6 -0.7 -0.5 -0.3 -0.8 -0.7 0.3 -0.3 -0.7 -1.4 -1.0 0.2 0.0 -0.5 -1.0 -0.7
Medication: Cholesterol lowering 0.7 1.1 3.2 1.4 1.2 -0.7 1.5 1.2 -1.4 -1.0 -0.7 1.4 1.7 -0.8 0.6 1.6 -0.6 -1.0 -0.9 -0.4 -1.4 -1.2 -0.5 -0.1 -0.8 -0.7 1.1 -0.5 -0.7 -1.3 -0.5 -1.0 0.6 -0.9 -1.8 -0.6
Depression (self-reported) 7.6 9.1 14.3 3.5 2.4 -3.2 2.8 2.7 -3.6 -3.4 -3.4 3.5 -2.6 -1.5 3.0 3.5 1.6 0.8 -3.4 -3.2 -3.2 -3.5 -3.5 -3.1 -2.6 -2.8 2.0 -3.8 -3.3 -3.0 -2.8 -3.1 -3.2 -3.4 -2.9 -2.9
Medication: Lansoprazole 0.6 0.7 1.4 0.8 0.3 -1.0 0.9 0.5 -0.8 -0.6 -0.7 0.9 -1.2 0.0 0.8 1.1 0.4 0.8 -1.1 -0.6 -1.0 -0.9 -0.5 -0.8 -0.7 -0.8 0.7 -0.8 -0.8 -0.2 -0.5 -1.1 -1.1 -1.2 -0.8 -0.9
Prospective memory result 0.9 1.1 3.7 -1.1 -0.6 1.9 -0.5 -0.6 1.1 1.1 1.9 -1.0 0.5 0.2 -1.3 -1.0 -0.8 -0.2 1.0 1.3 1.0 1.1 1.5 0.9 1.0 0.8 -0.5 1.4 1.1 1.6 1.3 0.7 0.6 1.1 1.1 1.0
Lung cancer (father) 1.8 2.2 3.6 1.6 0.7 -1.9 1.2 0.9 -1.6 -1.6 -1.7 1.6 -1.6 -1.7 1.2 0.9 0.8 0.1 -1.4 -1.6 -1.8 -1.6 -1.9 -1.8 -1.5 -1.7 0.4 -1.2 -1.9 -1.4 -1.6 -1.6 -1.6 -1.6 -1.4 -1.5
Illnesses of mother 0.4 0.5 4.5 -0.3 -1.0 -0.2 -0.2 -1.4 0.1 -0.2 -0.1 -0.3 -2.1 0.2 0.1 -0.3 0.9 0.7 0.0 -0.4 0.2 0.1 -0.5 -0.6 -0.4 0.3 -1.5 -0.7 -0.1 0.3 0.1 -0.6 -1.2 0.8 0.7 -0.0
Forced expiratory volume in 1-second (FEV1), Best measure 0.5 1.6 7.2 1.7 1.8 -0.5 1.2 2.7 -1.4 -1.1 -0.9 1.7 -1.1 1.2 1.4 1.8 -0.3 -0.5 -0.8 -1.1 -0.6 -1.2 -0.6 -1.4 -0.0 -1.6 2.4 -0.9 -0.9 -0.4 -1.5 -0.6 -1.1 -1.3 -0.6 -0.5
Pulse wave Arterial Stiffness index 2.6 3.0 5.3 -1.7 -0.3 2.3 -1.5 -0.6 1.9 1.9 1.7 -1.8 1.5 2.0 -1.8 -1.6 -1.5 -0.8 1.8 1.8 2.1 2.0 2.0 2.0 2.1 1.8 0.2 1.9 2.0 1.9 1.4 2.2 2.0 1.0 1.8 1.7
Impedance of arm (left) 1.1 5.3 27.2 -3.0 -5.2 0.6 -3.5 -3.9 2.3 1.3 1.8 -2.6 -0.4 0.8 -0.7 -2.4 3.2 4.7 0.7 1.4 1.8 1.6 1.6 1.1 -0.5 2.0 -3.7 0.6 0.9 2.3 2.1 2.0 -1.2 2.1 1.7 -0.6
Arm fat mass (right) 0.8 3.1 14.6 2.3 3.1 -1.3 1.7 3.7 -1.8 -1.6 -2.6 2.0 0.5 -0.3 1.9 2.6 -0.6 -1.7 -0.9 -1.4 -0.6 -1.4 -1.1 -0.9 0.2 -1.6 3.8 -1.6 -0.9 -1.7 -2.2 -0.0 0.4 -1.6 -1.2 -0.3
Trunk predicted mass 1.2 7.0 38.1 2.4 5.6 1.4 3.2 5.9 -1.1 0.3 -0.0 1.8 0.8 1.2 -0.4 2.5 -5.3 -6.2 1.0 0.6 0.8 -0.3 0.8 0.5 3.3 -0.7 6.1 0.3 1.1 0.3 -0.9 0.4 2.5 -1.0 0.6 2.5
Standing height 0.7 6.8 18.5 -0.6 1.7 3.2 0.6 3.0 1.5 2.4 2.8 -0.9 1.5 2.8 -2.1 0.2 -4.3 -3.6 2.6 2.8 3.1 1.9 3.3 2.5 4.1 1.7 3.6 1.9 3.0 3.3 1.7 2.8 2.9 1.2 2.7 3.2
Length of working week for main job 0.2 0.3 1.7 -0.1 0.2 -0.3 1.1 -0.6 0.0 0.0 -0.1 -0.1 -1.0 -1.0 0.0 -0.5 -0.4 -0.6 0.1 -0.3 -0.3 0.1 -0.1 -0.5 -0.1 -0.4 -0.9 0.4 0.2 -0.2 -0.1 -1.3 -0.2 0.6 -0.1 0.6
Exposure to tobacco smoke at home 0.3 0.3 1.8 0.0 -0.3 -0.7 -0.5 -0.6 -0.1 -0.2 -0.1 -0.0 -1.4 -1.3 0.1 -0.2 0.5 0.3 -0.3 -0.5 -0.2 -0.2 -0.8 -0.5 -0.4 0.0 -0.8 -0.9 -0.2 -0.5 -0.1 -1.0 -0.7 0.2 -0.0 -0.1
Breastfed as a baby 0.2 0.2 1.3 0.3 1.2 0.1 1.0 0.8 -0.1 0.0 -0.0 0.2 -1.1 -0.2 0.2 -0.2 -0.7 -0.6 -0.0 -0.2 -0.1 -0.1 -0.1 -0.4 0.3 -0.2 0.4 0.0 0.0 0.3 -0.2 -0.4 -0.4 -0.5 0.3 0.2
Tense / ‘highly strung’ 4.2 7.0 10.6 3.1 2.7 -2.5 3.1 2.7 -3.0 -2.9 -3.1 3.1 -0.7 -0.3 3.1 2.8 1.5 0.8 -2.9 -2.9 -2.4 -2.9 -2.4 -2.8 -1.9 -3.3 3.2 -2.8 -2.7 -2.7 -3.2 -1.7 -2.1 -3.2 -2.7 -2.5
Seen doctor (GP) for nerves, anxiety, tension or depression 1.1 1.7 7.0 1.9 2.6 -0.8 1.9 2.2 -1.5 -1.1 -1.5 1.6 -1.2 0.9 0.8 1.3 -0.8 -1.3 -0.9 -1.1 -0.8 -1.2 -1.2 -1.0 0.2 -1.1 2.5 -1.3 -0.9 -0.7 -1.2 -0.7 -0.7 -1.7 -0.6 -0.4
Hair/balding pattern: Pattern 4 0.8 2.0 3.5 1.5 0.6 -1.0 0.6 1.6 -1.6 -1.8 -1.3 1.5 0.2 -1.8 1.7 1.8 1.4 0.9 -1.5 -1.6 -1.5 -1.5 -1.1 -1.7 -1.8 -1.9 1.1 -1.3 -1.6 -1.2 -1.8 -0.6 -1.2 -0.8 -1.4 -1.4
Birth weight of first child 1.5 2.6 5.0 1.9 1.4 -1.6 1.5 1.4 -1.9 -1.8 -1.4 2.0 -1.1 -0.7 1.7 1.8 0.8 0.4 -1.7 -1.8 -1.9 -1.9 -1.4 -2.1 -1.4 -2.2 0.9 -1.3 -1.6 -1.7 -2.0 -2.1 -1.7 -1.5 -1.7 -1.3
Peak expiratory flow (PEF) 0.6 1.4 6.1 0.6 1.9 1.4 1.1 2.1 -0.0 0.5 1.1 0.5 -0.5 1.3 -0.5 0.7 -2.5 -2.4 0.7 0.7 0.8 0.3 1.1 0.0 1.6 -0.2 2.3 0.6 0.8 1.6 0.1 0.4 0.3 -0.0 1.0 1.2
Pulse wave reflection index 2.0 2.5 6.7 -2.1 -1.4 1.4 -2.6 -1.4 2.1 1.8 1.6 -2.1 1.0 0.8 -1.7 -2.0 -0.2 0.4 1.5 1.5 1.7 1.9 1.5 1.7 1.2 1.9 -1.4 1.5 1.5 1.5 1.5 1.8 1.3 1.2 1.6 1.0
Ever highly irritable/argumentative for 2 days 2.6 3.1 6.1 1.8 1.2 -2.3 1.0 1.1 -1.9 -1.9 -2.0 1.9 -1.4 0.2 2.5 1.9 1.7 1.2 -2.0 -1.9 -1.5 -2.0 -1.5 -2.0 -1.6 -2.1 1.3 -2.0 -1.8 -1.9 -2.0 -1.5 -2.0 -1.8 -1.8 -1.9
Loud music exposure frequency 0.1 0.1 0.4 -0.1 -0.1 -0.4 0.1 -0.0 0.1 -0.0 -0.5 -0.1 0.5 -0.1 0.2 0.5 0.4 0.6 -0.0 0.1 0.2 0.0 0.3 0.1 -0.0 -0.2 0.5 -0.3 0.2 -0.1 -0.1 0.2 0.2 0.6 -0.1 0.2
Qualifications: O levels/GCSEs or equivalent 0.3 0.5 3.1 0.5 0.1 -0.4 -0.3 0.2 -0.6 -0.9 -0.6 0.6 0.1 -1.8 0.9 1.2 1.1 1.1 -0.7 -0.5 -0.4 -0.7 -0.1 -0.7 -0.9 -0.8 0.1 -0.3 -0.6 -0.5 -0.7 -0.1 -1.0 -0.0 -0.6 -0.8
Mouth/teeth dental problems: Bleeding gums 5.4 7.0 14.4 2.0 -0.2 -3.5 1.5 0.0 -2.6 -2.9 -3.1 2.3 -0.4 -2.2 3.3 2.2 3.5 3.3 -3.3 -2.8 -3.2 -2.9 -2.3 -2.5 -3.8 -2.6 -0.1 -2.6 -2.9 -2.8 -2.3 -2.4 -2.6 -2.2 -3.5 -3.4
Blood clot in the leg (DVT) 1.5 1.9 11.8 1.7 2.9 0.1 1.2 3.1 -1.0 -0.4 -0.5 1.4 0.1 1.3 0.3 1.3 -1.8 -2.4 -0.2 -0.6 -0.1 -0.8 -1.0 -0.5 1.0 -1.1 3.4 -0.9 -0.5 -1.0 -1.4 -0.1 0.4 -1.9 -0.4 0.1
Medication: Paracetamol 0.9 1.5 3.0 1.2 1.1 -1.1 0.9 0.6 -1.3 -1.3 -1.3 1.3 0.6 -1.0 1.6 1.1 1.3 1.0 -1.5 -1.3 -1.2 -1.3 -0.7 -1.3 -1.3 -1.7 0.8 -0.5 -1.2 -1.6 -1.7 -0.8 -0.9 -1.3 -1.5 -1.3
Headache pain in last month 0.7 1.2 2.5 1.2 1.6 -1.3 0.8 1.4 -1.2 -1.1 -1.4 1.2 -0.6 -0.6 1.2 0.5 0.6 0.1 -1.0 -1.4 -1.0 -1.1 -1.2 -1.3 -0.7 -1.5 1.1 -1.0 -1.2 -1.4 -1.5 -0.9 -0.9 -1.4 -1.0 -0.9
Medication for cholesterol, blood pressure or diabetes 1.6 2.6 6.2 -2.2 -1.8 1.2 -2.5 -2.0 2.1 1.9 1.6 -2.2 -1.1 1.1 -1.3 -2.0 -0.0 0.6 1.7 1.2 1.9 1.9 1.2 1.0 1.4 1.6 -1.8 1.2 1.7 1.8 1.3 1.2 0.5 1.9 2.3 1.5
Glaucoma (self-reported) 0.1 0.2 1.3 -0.5 0.0 0.3 -0.8 -0.4 0.6 0.4 0.0 -0.5 -1.2 0.3 -0.3 -0.2 0.1 0.1 0.4 0.0 0.5 0.5 0.1 -0.3 0.4 -0.2 -0.3 0.2 0.1 0.6 0.1 0.1 -0.5 -0.1 0.5 0.0
Gout (self-reported) 0.5 0.7 2.0 0.3 -1.1 -1.3 -0.3 -0.7 -0.6 -0.9 -1.4 0.4 0.0 -1.1 1.0 0.8 1.2 1.3 -0.8 -0.4 -0.9 -0.7 -0.9 0.0 -1.2 0.3 -0.6 -1.4 -0.7 -1.0 0.2 -0.7 -0.2 -0.5 -1.3 -1.1
Hypothyroidism/myxoedema (self-reported) 2.8 5.5 14.5 1.3 0.0 -3.0 0.1 -0.7 -1.8 -2.5 -2.8 1.4 -1.0 -2.9 3.0 0.0 3.8 2.8 -2.4 -3.1 -2.4 -2.0 -2.3 -2.8 -3.3 -2.7 -0.8 -2.0 -2.6 -2.7 -2.9 -1.9 -2.5 -1.4 -2.5 -2.7
Medication: Amlodipine 0.1 0.2 1.2 0.2 0.1 -0.8 0.7 0.1 -0.2 -0.4 -1.1 0.2 -0.0 -0.5 0.6 -0.5 0.2 0.1 -0.3 -0.5 -0.6 -0.2 -0.5 -0.1 -0.5 -0.1 0.3 -0.8 -0.4 -0.2 -0.0 -0.3 0.1 -0.5 -0.6 -0.4
Medication: Ventolin 100micrograms inhaler 2.2 2.8 5.3 -1.5 -0.7 2.1 -1.4 -0.6 1.7 1.8 2.3 -1.6 1.4 0.4 -1.8 -1.4 -1.8 -1.5 2.0 1.8 1.6 1.8 1.8 1.6 1.6 1.6 -0.7 2.2 1.7 2.3 1.7 1.9 1.8 1.9 2.0 1.9
Birth weight 0.3 0.7 1.6 0.8 0.6 -0.8 1.3 1.0 -0.8 -0.8 -0.8 0.9 -0.7 0.3 0.6 0.9 0.7 0.6 -0.9 -0.9 -0.6 -0.9 -1.0 -0.7 -0.5 -0.7 0.7 -1.2 -1.0 -0.9 -0.7 -0.7 -0.9 -1.3 -0.9 -1.0
Chronic bronchitis/emphysema (mother) 0.5 0.6 3.5 0.9 1.9 -0.4 0.2 1.5 -0.5 -0.4 -1.1 0.7 0.1 0.7 0.2 0.9 -0.8 -1.1 -0.1 -0.4 -0.2 -0.4 -0.5 -0.0 0.4 -0.3 1.7 -0.3 -0.3 -0.6 -0.7 0.2 0.4 -1.1 -0.4 -0.0
High blood pressure (siblings) 0.2 0.2 0.8 0.5 0.1 -0.9 0.4 0.2 -0.5 -0.5 -0.9 0.4 0.6 -0.8 0.4 -0.2 0.2 0.1 -0.5 -0.3 -0.6 -0.5 -0.6 0.1 -0.6 0.0 0.4 -0.7 -0.5 -0.6 -0.2 -0.1 0.3 -0.6 -0.8 -0.6
Forced vital capacity (FVC), Best measure 0.3 0.9 5.4 1.4 1.3 -0.5 0.6 2.3 -1.2 -1.0 -0.9 1.3 -0.0 1.0 1.2 1.6 0.1 -0.0 -0.7 -0.7 -0.4 -1.1 -0.2 -0.7 -0.1 -1.1 2.0 -0.7 -0.6 -0.4 -1.1 0.1 -0.5 -0.7 -0.5 -0.2
Body fat percentage 0.7 2.6 8.3 1.7 1.7 -1.8 0.7 2.4 -1.6 -1.8 -2.9 1.6 0.9 -0.7 2.3 2.1 1.2 0.2 -1.3 -1.8 -0.9 -1.5 -1.5 -1.0 -0.9 -1.6 2.3 -1.9 -1.4 -2.3 -2.3 0.1 -0.1 -1.3 -1.5 -1.1
Leg fat percentage (right) 0.6 2.1 6.3 1.7 1.9 -1.2 0.6 2.2 -1.5 -1.6 -2.5 1.4 1.3 -0.6 1.7 1.5 0.7 -0.6 -1.0 -1.7 -0.8 -1.3 -1.5 -0.9 -0.6 -1.5 2.2 -1.3 -1.3 -2.4 -2.3 0.1 0.4 -1.1 -1.3 -0.6
Arm fat-free mass (right) 1.6 8.1 42.9 3.6 6.4 0.2 4.0 6.4 -2.4 -1.0 -1.3 3.0 0.5 0.5 0.9 3.6 -4.4 -5.6 -0.3 -0.8 -0.5 -1.6 -0.6 -0.7 2.1 -1.9 6.5 -0.9 -0.2 -1.2 -2.2 -0.8 1.6 -2.4 -0.9 1.2
Exposure to tobacco smoke outside home 0.4 0.6 2.9 0.3 -0.6 -0.9 -0.2 -1.0 -0.5 -0.4 -0.0 0.4 -1.7 -1.7 0.6 -0.2 0.7 0.9 -0.8 -0.4 -0.7 -0.6 -0.5 -0.6 -0.9 0.0 -0.9 -0.9 -0.5 -0.0 0.2 -1.3 -1.2 -0.2 -0.5 -0.7
Comparative body size at age 10 0.4 1.2 7.1 0.5 1.9 0.4 -1.0 2.0 -0.1 0.1 -0.6 0.3 2.2 2.1 -0.3 1.2 -1.1 -1.4 0.5 0.3 0.9 0.2 0.4 0.6 1.3 -0.3 2.7 0.1 0.4 -0.4 -0.7 1.5 1.5 -0.3 0.2 0.8
Number of full brothers 0.5 0.6 2.9 0.8 0.5 -1.1 1.7 0.3 -0.8 -0.4 -0.7 0.8 -1.4 -1.0 0.2 -0.3 -0.9 -0.9 -0.6 -0.4 -1.3 -0.7 -1.0 -0.5 -0.4 -0.2 -0.2 -0.2 -0.6 -0.3 0.0 -1.5 -0.5 -1.0 -0.5 -0.3
Worry too long after embarrassment 0.1 0.2 1.3 0.1 0.2 -0.2 0.4 -0.5 -0.1 -0.0 0.3 0.2 -1.1 -0.0 0.0 0.2 -0.1 0.2 -0.2 -0.0 -0.4 -0.2 0.2 -0.5 -0.2 -0.3 -0.7 0.7 -0.0 0.3 0.0 -0.7 -0.8 0.1 0.1 0.0
Seen a psychiatrist for nerves, anxiety, tension or depression 6.4 8.3 14.8 3.8 3.2 -2.1 3.9 2.8 -3.6 -3.3 -2.6 3.7 -2.1 -1.2 2.6 2.8 0.8 -0.2 -3.1 -3.2 -3.2 -3.4 -2.8 -3.4 -2.2 -3.5 2.4 -2.6 -3.0 -2.6 -3.2 -3.0 -2.9 -3.3 -2.7 -2.4
Wheeze or whistling in the chest in last year 1.1 2.0 6.4 -1.0 0.6 1.1 -1.2 -0.5 1.3 1.5 0.9 -1.2 -0.6 1.1 -1.4 -1.6 -2.3 -2.5 2.0 1.0 1.2 1.6 0.5 1.2 1.9 1.7 -0.4 1.3 1.5 1.4 1.2 0.9 1.6 1.2 1.9 2.2
Number of children fathered 0.9 1.0 6.1 -0.2 1.5 1.3 0.8 1.1 0.6 0.8 0.7 -0.4 0.2 0.9 -1.1 -0.5 -1.9 -2.5 1.1 0.4 0.9 0.9 0.5 0.2 1.5 -0.1 1.0 1.1 0.8 0.4 -0.0 0.6 1.0 0.4 0.9 1.4
Reason for reducing amount of alcohol drunk: Health precaution 1.4 1.6 7.1 1.6 2.0 -0.1 1.1 2.7 -1.3 -1.1 -0.6 1.5 0.1 0.1 1.0 1.7 0.1 -0.4 -1.0 -1.2 -0.7 -1.1 -0.9 -1.3 -0.2 -2.0 2.4 -0.3 -1.2 -1.3 -2.0 -0.2 -0.7 -1.7 -1.0 -0.7
Age at first live birth 0.9 1.5 3.6 1.6 1.1 -0.7 1.3 1.8 -1.5 -1.4 -0.7 1.7 -0.4 0.1 1.0 1.9 0.4 0.2 -1.4 -1.1 -1.3 -1.5 -1.1 -1.3 -1.0 -1.6 1.4 -1.2 -1.4 -1.1 -1.2 -1.1 -1.2 -1.4 -1.3 -1.2
Pulse wave peak to peak time 1.9 2.2 4.2 1.5 0.3 -2.1 1.4 0.6 -1.7 -1.7 -1.4 1.6 -1.1 -1.9 1.6 1.5 1.3 0.7 -1.5 -1.5 -1.9 -1.7 -1.6 -1.6 -1.8 -1.5 -0.1 -1.6 -1.6 -1.6 -1.1 -1.8 -1.6 -0.7 -1.5 -1.4
Health satisfaction 0.1 0.1 0.5 0.1 -0.1 -0.7 0.5 -0.5 -0.3 -0.1 -0.4 0.2 -0.6 -0.6 0.5 0.4 0.1 0.2 -0.3 -0.2 -0.4 -0.2 -0.1 -0.4 -0.5 -0.3 -0.3 -0.2 -0.2 0.0 -0.2 -0.7 -0.3 0.1 -0.3 -0.2
Shortness of breath walking on level ground 0.7 0.8 2.6 1.0 1.2 -0.7 0.8 0.6 -1.0 -0.9 -1.2 0.9 1.3 -0.4 0.7 0.7 0.1 -0.2 -1.0 -0.7 -1.0 -0.9 -0.6 -0.5 -0.6 -1.0 1.0 -0.3 -0.8 -1.6 -1.0 -0.7 0.0 -1.4 -1.5 -0.8
Qualifications: College or University degree 0.3 0.8 5.7 -1.1 -2.4 0.0 -1.3 -1.1 0.9 0.5 0.5 -1.0 -0.5 0.1 0.1 -0.1 0.9 1.6 0.4 0.7 0.5 0.6 0.5 0.6 -0.3 1.1 -1.4 -0.1 0.4 1.2 1.1 0.8 -0.1 1.4 0.7 0.2
Eye problems/disorders: None of the above 0.3 0.4 1.1 -0.5 -0.2 0.8 -0.1 -0.3 0.6 0.5 0.4 -0.5 0.3 0.3 -0.8 -0.3 -0.6 -0.7 0.9 0.8 1.1 0.7 0.5 0.7 0.9 0.7 0.0 0.5 0.7 0.2 0.4 0.8 0.7 0.9 0.8 0.8
Mouth/teeth dental problems: Loose teeth 0.2 0.3 1.7 0.6 0.4 -0.1 0.5 0.4 -0.5 -0.6 -0.6 0.6 0.2 0.2 0.5 1.3 0.3 0.0 -0.3 -0.1 0.2 -0.5 -0.1 -0.2 -0.2 -0.1 1.0 -1.3 -0.1 -0.4 -0.4 0.0 -0.2 0.1 -0.5 -0.4
Emphysema/chronic bronchitis 1.1 1.2 5.5 1.5 2.4 -0.1 0.9 1.9 -1.2 -1.2 -1.0 1.4 -0.2 0.2 1.0 1.2 -0.4 -1.1 -0.7 -1.1 -0.6 -1.0 -0.6 -1.1 -0.1 -1.5 2.0 -0.4 -0.8 -0.9 -1.7 -0.4 -0.6 -1.2 -0.7 -0.4
Medication for pain relief, constipation, heartburn 1.5 2.6 4.7 -1.9 -1.3 1.6 -1.4 -1.7 1.9 2.0 2.1 -1.9 -0.6 0.7 -2.2 -1.8 -1.0 -0.6 1.9 1.6 1.8 1.9 1.2 1.4 1.6 1.9 -1.7 1.5 1.6 1.8 1.8 1.1 0.9 1.8 2.2 1.7
Neck or shoulder pain in last month 0.9 1.3 4.1 1.2 1.6 -0.9 0.1 1.4 -1.1 -1.1 -1.2 1.2 0.5 0.1 1.3 1.1 1.0 0.3 -0.9 -1.6 -1.0 -1.1 -1.0 -1.3 -0.8 -1.8 1.5 -0.6 -1.2 -1.6 -2.0 -0.1 -0.4 -0.9 -1.0 -0.6
Medication: Blood pressure 1.4 2.5 7.4 2.3 2.7 -1.1 2.7 2.6 -1.9 -1.6 -1.8 2.2 0.2 -0.1 1.1 2.0 -0.7 -1.0 -1.5 -0.9 -1.4 -1.8 -1.0 -0.9 -0.6 -1.4 2.5 -1.2 -1.3 -1.3 -1.1 -1.2 -0.6 -2.0 -1.8 -1.1
Angina (self-reported) 1.3 1.7 3.6 -1.2 0.0 1.4 0.2 -0.4 1.4 1.5 1.5 -1.3 0.8 0.9 -1.6 -1.5 -1.7 -1.9 1.6 1.2 1.0 1.5 1.2 1.1 1.4 1.0 -0.6 1.7 1.3 1.5 1.3 0.8 1.6 1.3 1.3 1.6
Migraine (self-reported) 1.0 1.2 4.8 1.0 0.9 -1.1 0.8 0.8 -1.0 -1.2 -1.3 1.0 -0.3 -2.2 1.2 0.2 1.1 0.4 -1.1 -1.4 -1.0 -1.1 -1.2 -1.2 -1.1 -1.3 0.5 -1.0 -1.2 -1.4 -1.5 -0.7 -1.0 -1.1 -1.0 -1.1
Medication: Ibuprofen 0.4 0.5 1.7 0.4 0.5 -0.7 0.5 0.1 -0.6 -0.8 -1.1 0.5 1.0 0.6 0.9 -0.0 1.3 1.0 -0.7 -0.8 -0.5 -0.6 -0.5 -0.3 -0.7 -0.7 0.3 -0.2 -0.7 -1.3 -1.0 0.3 -0.1 -0.6 -0.8 -0.7
Medication: Allopurinol 0.2 0.3 2.2 -0.3 -1.5 -0.1 -0.7 -0.7 0.1 -0.1 -0.1 -0.2 0.6 -0.9 -0.0 0.6 0.5 1.0 -0.2 0.6 -0.0 -0.0 0.4 0.5 -0.5 0.6 -0.7 0.0 0.0 0.3 0.8 0.1 -0.1 0.2 -0.4 -0.5
Medication: Omeprazole 0.3 0.3 1.7 0.6 0.9 0.4 0.1 0.6 -0.4 -0.2 -0.0 0.6 -1.3 -0.1 0.1 -0.2 -0.9 -1.1 -0.1 -0.4 -0.3 -0.3 -0.1 -0.8 0.2 -0.7 0.7 0.2 -0.1 0.3 -0.4 -0.9 -0.6 -0.5 0.0 0.3
Medication: Seretide 50 evohaler 0.7 0.8 2.6 1.2 1.1 -0.5 1.6 1.1 -1.0 -1.1 -1.0 1.1 0.4 -1.5 0.9 0.6 -0.0 -0.8 -0.6 -0.8 -0.8 -0.9 -0.7 -0.6 -0.5 -0.9 1.0 -0.5 -0.7 -0.9 -1.1 -0.3 -0.1 -0.8 -0.9 -0.5
Mean time to correctly identify matches 0.0 0.1 0.4 0.2 0.3 -0.3 -0.5 0.6 -0.2 -0.1 -0.2 0.2 -0.4 -0.3 0.1 0.3 0.1 0.4 -0.1 -0.1 -0.0 -0.2 -0.1 -0.3 -0.0 -0.3 0.3 -0.1 -0.1 0.0 -0.4 0.1 -0.3 0.1 0.1 0.1
Heart disease (mother) 0.4 0.5 3.0 0.3 0.5 -0.3 0.0 1.0 -0.3 -0.6 -1.1 0.3 1.7 -1.0 0.7 0.5 0.8 0.6 -0.4 -0.5 -0.4 -0.4 -0.5 0.2 -0.5 -0.4 0.6 -0.2 -0.5 -1.3 -0.7 0.7 0.7 -0.5 -0.9 -0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.2 0.2 0.8 -0.7 -0.2 -0.2 -0.5 -0.8 0.6 0.6 0.2 -0.7 0.2 0.0 -0.5 -0.7 0.1 -0.0 0.4 0.2 0.2 0.6 0.4 0.2 0.1 0.2 -0.9 0.8 0.4 0.2 0.2 0.4 0.4 0.7 0.4 0.4
Whole body fat mass 0.8 3.5 15.5 2.4 3.2 -1.4 1.8 3.9 -1.9 -1.7 -2.7 2.1 0.8 -0.4 2.0 2.7 -0.5 -1.6 -1.0 -1.5 -0.7 -1.5 -1.2 -0.9 0.1 -1.8 3.9 -1.6 -1.0 -2.0 -2.4 -0.1 0.5 -1.6 -1.3 -0.3
Leg fat mass (right) 1.1 4.3 17.5 2.7 3.8 -1.2 2.0 4.2 -2.2 -1.8 -2.8 2.3 0.8 -0.5 2.0 2.7 -0.9 -2.4 -1.0 -1.8 -1.0 -1.7 -1.6 -1.2 0.1 -2.0 4.1 -1.6 -1.2 -2.3 -2.7 -0.3 0.6 -1.8 -1.4 -0.2
Arm predicted mass (right) 1.4 7.3 40.3 3.3 6.2 0.3 3.6 6.2 -2.1 -0.8 -1.2 2.7 0.8 0.6 0.7 3.4 -4.2 -5.4 -0.1 -0.6 -0.3 -1.3 -0.4 -0.5 2.1 -1.8 6.3 -0.7 -0.1 -1.1 -2.1 -0.5 1.7 -2.1 -0.7 1.3
Pulse rate, automated reading 0.1 0.2 1.0 0.3 0.9 0.6 1.0 0.5 -0.1 -0.1 -0.0 0.2 -0.2 1.0 0.3 0.9 -0.5 -0.7 0.2 0.0 0.4 0.0 0.3 -0.2 0.4 -0.3 0.7 0.2 0.1 0.1 -0.4 0.1 0.1 -0.4 -0.0 -0.0
Alcohol intake frequency. 0.1 0.2 1.4 0.5 0.8 0.2 0.5 0.5 -0.3 0.1 0.0 0.4 0.4 1.1 -0.3 -0.2 -1.1 -1.2 0.0 0.1 -0.1 -0.2 -0.1 0.1 0.5 -0.2 0.9 0.2 0.0 -0.3 -0.3 -0.1 0.2 -0.8 -0.0 0.1
Comparative height size at age 10 0.8 4.2 16.4 0.4 2.8 2.1 0.4 3.5 0.6 1.5 1.5 0.1 0.2 2.3 -1.4 0.9 -3.8 -3.8 1.8 1.7 2.3 1.0 1.9 1.3 3.5 0.8 4.0 0.5 1.9 2.4 0.7 1.7 1.7 0.1 1.9 2.2
Number of full sisters 1.9 2.3 4.3 1.4 0.6 -1.9 1.7 0.9 -1.5 -1.8 -2.1 1.4 -0.9 -0.9 1.6 0.8 1.6 1.0 -1.5 -1.9 -1.6 -1.5 -1.9 -1.7 -1.6 -1.8 0.6 -1.7 -1.8 -1.7 -1.9 -1.1 -1.5 -1.7 -1.5 -1.7
Suffer from ‘nerves’ 1.7 2.7 7.1 2.2 2.3 -0.9 2.7 2.1 -2.0 -1.7 -1.2 2.2 0.2 -0.1 1.4 1.6 0.3 -0.2 -1.7 -1.6 -1.4 -1.9 -1.2 -1.5 -0.8 -2.0 2.5 -1.2 -1.7 -1.5 -2.0 -0.7 -1.2 -2.4 -1.5 -1.5
Overall health rating 0.7 1.5 5.4 1.3 1.8 -1.2 1.1 1.0 -1.1 -1.2 -1.6 1.1 -2.3 -1.1 1.4 -0.0 -0.1 -1.4 -0.5 -1.9 -1.1 -0.9 -1.8 -1.6 -0.5 -1.3 0.8 -1.1 -1.0 -1.0 -1.8 -1.2 -0.8 -1.2 -0.5 -0.3
Chest pain or discomfort 1.0 1.4 5.0 1.2 2.1 -1.5 0.9 1.1 -1.0 -1.1 -2.2 1.1 -1.5 -0.3 1.1 -0.0 -0.4 -1.3 -0.4 -1.6 -1.1 -0.8 -1.8 -1.3 -0.2 -1.2 0.8 -0.7 -1.1 -1.4 -1.5 -1.2 -0.5 -1.4 -0.7 -0.2
Had major operations 1.1 1.3 3.5 1.0 0.1 -1.3 1.7 -0.1 -1.2 -1.0 -0.9 1.0 -1.5 -1.9 0.8 0.6 0.3 0.3 -1.3 -0.9 -1.7 -1.2 -1.6 -0.8 -1.4 -0.3 -0.7 -1.2 -1.3 -0.9 -0.0 -1.7 -1.2 -1.6 -1.4 -1.5
Age at last live birth 0.4 0.6 2.8 0.9 0.5 0.0 0.6 1.6 -0.8 -0.8 -0.2 1.0 0.1 0.2 0.9 1.7 0.4 0.8 -0.8 -0.3 -0.2 -0.9 0.1 -0.7 -0.3 -1.0 1.7 -0.8 -0.4 -0.1 -0.8 -0.1 -0.8 -0.3 -0.5 -0.4
Family relationship satisfaction 0.6 0.7 1.7 0.4 0.2 -1.2 0.4 -0.3 -0.6 -0.9 -0.9 0.5 -0.7 -1.0 0.8 0.8 1.2 1.0 -0.9 -0.9 -1.1 -0.7 -0.7 -0.9 -1.3 -0.9 -0.7 -0.5 -1.0 -0.5 -0.6 -1.1 -1.0 -0.6 -1.1 -1.1
Leg pain on walking 0.1 0.1 0.5 0.1 0.0 -0.5 0.5 0.1 -0.1 -0.0 -0.4 0.2 0.1 -0.1 0.1 -0.3 -0.1 0.2 -0.1 0.0 0.0 -0.1 0.5 -0.0 0.1 -0.3 0.7 0.4 0.0 0.6 -0.1 0.3 -0.1 -0.2 0.0 0.0
Qualifications: NVQ or HND or HNC or equivalent 1.1 1.3 7.0 -1.6 -2.2 -0.2 -2.6 -1.7 1.2 0.7 0.2 -1.6 0.8 0.6 -0.1 -1.3 2.1 2.0 0.5 -0.1 0.8 1.0 0.0 0.6 -0.3 0.7 -1.8 0.2 0.2 -0.2 0.2 1.4 0.5 1.4 0.6 0.2
Commuting to job workplace: Car/motor vehicle 1.3 1.4 6.2 1.9 2.5 0.0 1.9 2.0 -1.5 -0.8 -0.3 1.7 -0.3 0.4 0.5 1.2 -1.6 -2.2 -0.7 -0.6 -0.8 -1.2 -0.7 -0.8 0.2 -1.0 2.1 -0.8 -0.4 -0.8 -1.1 -1.2 -0.1 -1.1 -0.7 0.0
Illness, injury, bereavement, stress in last 2 years 0.2 0.2 1.0 0.4 0.2 -1.0 0.0 0.7 -0.4 -0.5 -0.7 0.4 -0.1 -0.4 0.7 0.0 0.3 0.2 -0.5 -0.5 -0.6 -0.4 -0.5 -0.3 -0.6 -0.2 0.2 -0.8 -0.5 -0.2 -0.3 -0.4 -0.2 -0.5 -0.5 -0.6
Medication: Aspirin 0.6 0.7 4.0 1.0 1.1 -0.1 1.3 2.0 -0.8 -0.7 -0.3 0.9 1.4 0.1 0.6 1.5 -0.5 -1.3 -0.3 -0.3 -0.5 -0.6 -0.4 -0.3 -0.2 -0.9 1.7 -0.5 -0.5 -0.8 -0.8 -0.0 0.5 -0.5 -0.8 -0.3
Supplements: Vitamin C 0.9 1.1 5.3 -1.4 -2.3 0.1 -1.4 -1.6 1.1 0.6 0.4 -1.3 -0.3 0.6 -0.3 -1.0 1.7 2.2 0.5 0.4 1.1 0.8 0.4 0.7 -0.1 1.1 -1.6 -0.1 0.5 0.5 0.5 1.1 -0.2 1.3 0.9 0.0
Knee pain experienced in last month 0.5 0.8 4.7 -0.9 -1.1 -0.9 -2.2 -1.5 0.5 -0.1 -0.8 -0.9 0.1 -0.1 0.5 -1.1 1.9 1.8 -0.1 -0.6 -0.1 0.3 -0.5 0.2 -0.9 0.5 -1.8 0.0 -0.3 -0.5 0.0 0.7 -0.0 0.2 -0.1 -0.6
Hypertension (Self-reported) 0.4 1.0 2.0 1.2 0.8 -1.1 1.3 1.1 -1.2 -1.2 -1.4 1.2 0.7 -1.1 1.0 0.5 0.4 0.2 -1.2 -1.0 -1.3 -1.2 -0.7 -0.7 -1.1 -1.0 1.0 -0.8 -1.0 -1.0 -1.0 -0.7 -0.2 -0.8 -1.4 -0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.2 0.2 1.9 0.4 0.5 0.2 -0.3 0.1 -0.4 -0.2 0.0 0.4 -1.4 0.9 -0.0 -0.0 -0.2 -0.2 -0.3 -0.6 -0.5 -0.3 -0.6 -0.6 -0.1 -0.3 0.2 -0.2 -0.5 0.1 -0.4 -0.5 -0.7 -0.9 -0.1 -0.3
Illnesses of father: Heart disease 0.2 0.3 2.4 -0.6 -1.5 0.3 -0.6 -0.8 0.4 0.1 0.4 -0.4 1.1 0.4 -0.0 -0.3 0.7 1.3 -0.0 0.3 -0.2 0.2 0.6 0.3 -0.5 0.1 -0.7 0.7 0.1 0.4 0.3 0.7 0.3 0.5 -0.1 -0.1
Illnesses of siblings: Diabetes 0.4 0.4 3.2 0.5 0.8 0.3 0.3 0.9 -0.3 -0.1 -0.1 0.4 1.8 -0.1 0.3 0.8 -1.4 -1.6 0.1 0.4 -0.4 -0.2 0.1 0.6 0.1 0.1 0.9 0.1 0.1 -0.4 0.3 -0.1 1.3 -0.5 -0.8 0.0
Smoking status: Previous 0.1 0.1 0.4 0.1 0.5 -0.3 -0.6 0.4 -0.1 -0.1 -0.6 -0.1 0.2 -0.1 0.4 0.1 0.2 -0.3 0.2 -0.3 0.1 0.0 -0.3 0.1 0.1 0.1 0.2 -0.3 0.0 -0.5 -0.4 0.4 0.5 0.4 0.1 0.3
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.6 4.0 0.5 1.5 0.5 1.3 1.5 -0.2 -0.1 -0.1 0.5 1.2 0.6 0.3 0.2 -0.7 -0.9 0.2 0.1 0.3 -0.1 0.8 0.1 0.8 -0.7 2.0 0.7 0.2 -0.1 -0.5 0.9 0.7 -0.4 0.1 0.4
Whole body fat-free mass 1.3 7.2 41.6 3.0 6.0 0.6 3.6 6.2 -1.8 -0.4 -0.9 2.5 0.4 0.8 0.4 3.1 -4.8 -5.8 0.3 -0.2 0.2 -0.9 0.1 -0.1 2.7 -1.3 6.5 -0.4 0.4 -0.4 -1.6 -0.1 1.9 -1.7 -0.1 1.8
Leg fat-free mass (right) 1.4 7.5 41.0 3.6 5.9 -0.5 3.9 6.2 -2.4 -1.3 -1.9 3.1 -0.5 0.2 1.3 3.7 -3.8 -4.8 -0.5 -1.0 -0.6 -1.7 -0.7 -1.0 1.8 -2.0 6.4 -1.4 -0.4 -0.9 -2.3 -0.9 0.7 -2.4 -0.9 0.9
Arm fat percentage (left) 0.8 3.1 9.2 2.0 1.9 -2.0 1.1 2.6 -1.9 -2.0 -3.0 1.9 0.1 -0.7 2.3 2.3 1.0 -0.0 -1.5 -1.9 -1.1 -1.7 -1.7 -1.4 -0.9 -1.8 2.5 -2.1 -1.6 -2.2 -2.4 -0.4 -0.6 -1.6 -1.6 -1.2
Average weekly red wine intake 0.6 0.8 5.1 1.1 1.6 0.3 0.6 2.3 -0.8 -0.8 -0.3 1.0 0.2 -0.2 0.3 1.4 0.2 -0.2 -0.5 -1.0 -0.2 -0.7 -0.9 -0.7 0.0 -0.9 1.9 -0.8 -0.7 -1.1 -1.4 0.6 -0.3 -1.0 -0.3 -0.4
Handedness (chirality/laterality): Left-handed 0.4 0.5 2.7 0.4 -0.2 -1.4 -0.3 -0.7 -0.5 -0.5 -0.8 0.3 -1.4 -1.7 0.3 0.2 0.4 0.3 -0.5 -0.5 -0.5 -0.5 -1.0 -0.5 -0.6 0.1 -1.0 -0.7 -0.6 -0.7 -0.1 -1.1 -0.9 -0.3 -0.4 -0.5
Mood swings 3.4 6.2 11.7 3.1 2.8 -2.4 3.2 3.0 -2.9 -2.7 -3.1 3.0 -0.4 0.2 2.4 2.5 0.9 -0.1 -2.6 -2.5 -2.2 -2.8 -2.3 -2.2 -1.5 -2.7 3.3 -2.8 -2.4 -2.6 -2.8 -1.6 -1.6 -3.4 -2.6 -2.4
Loneliness, isolation 0.6 0.9 3.5 1.0 1.4 -0.8 1.6 1.0 -0.9 -0.9 -1.0 1.0 0.0 0.7 0.9 0.5 0.4 -0.1 -0.8 -0.9 -0.5 -0.9 -0.5 -0.9 -0.4 -1.2 1.9 -1.2 -0.7 -0.7 -1.2 -0.2 -0.5 -1.2 -0.8 -0.8
Long-standing illness, disability or infirmity 0.8 1.3 2.7 1.1 1.3 -1.2 0.6 0.8 -1.1 -1.1 -1.4 1.1 -1.3 -1.2 1.5 0.5 0.3 -0.4 -0.8 -1.5 -1.5 -1.0 -1.2 -1.6 -1.1 -1.6 0.3 -0.3 -1.3 -0.9 -1.4 -1.4 -1.0 -1.2 -1.1 -0.8
Ever had bowel cancer screening 1.1 1.3 5.0 0.8 0.3 -1.9 0.2 0.2 -1.0 -1.1 -2.2 0.9 0.1 0.4 1.2 1.2 1.3 1.3 -1.2 -1.2 -1.2 -1.1 -1.4 -0.7 -1.2 -0.8 0.2 -1.1 -1.3 -1.8 -1.0 -0.6 -0.6 -1.3 -1.3 -1.3
Diabetes diagnosed by doctor 0.9 1.5 3.3 1.5 1.6 -1.4 0.7 1.5 -1.5 -1.3 -1.8 1.4 0.7 0.0 1.5 1.3 0.3 -0.5 -1.1 -1.4 -1.5 -1.3 -1.0 -0.9 -0.9 -1.5 1.6 -1.0 -1.1 -1.5 -1.4 -0.8 0.1 -1.5 -1.8 -0.9
Ever had stillbirth, spontaneous miscarriage or termination 1.5 1.6 4.6 1.6 1.8 -1.2 0.6 2.1 -1.4 -1.3 -1.6 1.6 -0.3 -1.1 1.5 1.9 0.1 0.0 -1.2 -1.1 -0.9 -1.3 -0.6 -1.2 -0.5 -1.6 2.1 -1.1 -1.0 -0.9 -1.5 -0.8 -0.8 -1.2 -0.9 -0.7
Friendships satisfaction 2.1 2.6 4.8 1.4 1.2 -1.9 1.3 1.1 -1.5 -1.7 -2.1 1.5 -0.1 -0.8 1.9 2.0 1.5 1.2 -1.9 -1.7 -1.9 -1.6 -1.1 -1.6 -1.8 -2.2 1.1 -1.3 -1.8 -1.6 -1.7 -1.2 -1.1 -1.9 -2.2 -2.0
Qualifications: nursing, teaching 0.4 0.6 1.4 1.0 1.0 -0.5 0.7 1.2 -0.9 -0.8 -0.8 1.0 -1.0 -0.9 1.1 0.9 -0.1 -0.2 -0.7 -0.7 -0.7 -0.8 -0.3 -0.9 -0.5 -0.9 0.9 -0.6 -0.6 -0.0 -0.7 -0.8 -0.8 -0.4 -0.5 -0.3
Commuting to job workplace: Walk 0.6 0.7 3.3 -1.1 -1.8 0.1 -0.5 -1.6 1.0 0.6 0.4 -1.1 -1.1 -0.5 -0.4 -1.7 0.3 0.5 0.7 0.4 0.3 0.8 -0.1 0.4 -0.1 0.9 -1.7 0.2 0.2 0.9 1.1 0.2 -0.1 0.6 0.6 0.1
Eye problems/disorders: Cataract 0.5 0.5 1.6 0.9 0.5 -0.4 0.4 0.5 -0.9 -0.8 -0.2 0.8 -0.0 -0.9 0.8 0.4 0.2 -0.1 -0.8 -0.8 -1.1 -0.9 -0.6 -0.7 -0.8 -0.9 0.5 -0.6 -0.7 -0.5 -0.7 -0.9 -0.5 -1.2 -1.1 -1.0
Mouth/teeth dental problems: Mouth ulcers 0.7 1.2 2.9 1.7 1.4 -1.3 1.5 1.2 -1.5 -1.0 -1.0 1.6 -0.3 0.4 0.6 1.5 -0.6 -0.9 -1.1 -0.7 -1.4 -1.4 -1.0 -0.6 -0.5 -0.8 1.2 -0.9 -0.9 -0.9 -0.7 -1.2 -0.5 -1.4 -1.1 -0.6
Medication for cholesterol 0.1 0.2 1.4 0.3 -0.2 0.1 1.2 0.5 -0.3 -0.4 0.3 0.4 0.1 -0.7 0.1 0.5 0.1 0.3 -0.3 0.2 -0.0 -0.4 0.3 0.1 -0.2 0.1 0.3 -0.4 -0.2 0.4 0.2 0.1 -0.4 -0.4 -0.3 -0.6
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.2 0.3 1.9 -0.3 -1.4 -0.1 -0.5 -0.4 0.2 0.2 0.4 -0.2 -1.1 0.4 -0.2 0.2 0.0 0.6 -0.0 0.6 0.1 0.1 0.3 0.0 -0.3 0.5 -0.7 -0.4 0.1 1.0 0.9 -0.4 -0.9 0.4 0.3 -0.3
Back pain experienced in last month 0.1 0.1 0.4 0.6 0.1 -0.3 0.5 0.2 -0.6 -0.5 -0.4 0.5 -0.4 0.1 0.5 0.0 0.2 0.2 -0.6 0.0 -0.1 -0.5 0.0 -0.3 -0.3 -0.2 0.4 -0.5 -0.2 -0.1 -0.2 -0.2 -0.6 -0.1 -0.2 -0.5
Mineral and other dietary supplements 0.1 0.1 0.9 -0.3 -0.2 -0.7 0.2 0.1 0.2 0.2 -0.5 -0.2 -0.5 -1.0 0.4 0.2 -0.2 -0.0 0.1 0.1 -0.2 0.2 0.4 -0.2 -0.1 -0.2 -0.3 0.2 0.3 0.5 0.3 -0.5 0.2 0.8 0.1 0.5
Breast cancer (self-reported) 2.4 2.9 5.6 2.0 0.4 -1.6 1.3 0.6 -2.1 -2.1 -1.6 1.9 -0.6 -1.6 2.0 1.6 1.5 0.7 -2.0 -1.9 -2.1 -2.1 -2.2 -1.4 -2.0 -1.2 0.5 -2.4 -1.9 -2.0 -1.4 -1.6 -1.3 -1.6 -2.1 -1.9
Asthma (self-reported) 1.2 2.4 5.0 -1.4 0.2 1.7 -1.0 -0.2 1.6 1.5 1.1 -1.6 1.1 1.4 -1.3 -1.8 -1.4 -1.7 2.1 1.3 1.7 1.8 1.2 1.5 1.9 1.4 -0.3 1.8 1.7 1.1 1.0 2.1 2.1 1.9 2.1 2.2
Osteoporosis (self-reported) 0.2 0.2 1.3 -0.2 -0.2 0.7 -0.6 -0.5 0.1 0.1 0.7 -0.2 -1.2 0.8 0.1 -0.3 -0.1 -0.2 0.2 0.3 0.2 0.2 0.1 -0.0 -0.1 0.5 -0.8 -0.1 0.2 0.7 0.6 -0.2 -0.5 0.7 0.5 0.1
Osteoarthritis (self-reported) 0.7 1.0 1.8 1.0 0.6 -0.8 0.4 0.7 -1.1 -1.1 -0.9 1.0 -0.9 0.2 1.2 0.8 0.7 0.1 -1.0 -1.3 -1.3 -1.0 -1.4 -1.2 -1.2 -0.9 0.1 -0.9 -1.3 -0.7 -1.1 -0.8 -1.1 -1.2 -0.9 -1.2
Medication: Aspirin 0.6 0.7 3.2 1.0 1.4 -0.2 1.4 1.8 -0.8 -0.6 -0.3 0.9 1.3 0.0 0.5 1.5 -0.7 -1.5 -0.3 -0.3 -0.6 -0.6 -0.3 -0.4 -0.2 -1.0 1.5 -0.3 -0.5 -0.7 -0.8 -0.3 0.4 -0.5 -0.9 -0.2
Medication: Gliclazide 3.6 4.1 9.6 1.7 0.6 -2.7 0.9 0.9 -2.0 -2.5 -3.1 1.8 -0.8 -1.9 2.8 1.7 2.1 1.7 -2.2 -2.2 -2.2 -2.1 -2.0 -1.9 -2.4 -2.0 0.5 -2.3 -2.1 -2.3 -1.8 -1.8 -1.8 -1.8 -2.5 -2.3
Illnesses of father: None of the above (group 1) 0.2 0.3 1.6 0.3 0.7 0.4 0.4 0.7 -0.1 0.3 0.7 0.2 -1.3 -0.5 -0.2 0.2 -1.0 -1.2 0.4 0.1 0.3 0.1 0.1 -0.4 0.6 -0.2 0.5 -0.1 0.2 0.7 0.1 -0.5 -0.5 -0.0 0.6 0.4
Smoking status: Current 1.3 2.1 6.2 1.2 0.2 -1.6 0.6 0.2 -1.3 -1.7 -1.5 1.2 -1.7 -1.0 1.7 1.3 2.0 1.3 -1.4 -1.9 -1.2 -1.4 -1.7 -1.8 -1.6 -1.5 0.6 -2.5 -1.6 -1.2 -1.7 -1.1 -1.7 -1.0 -1.2 -1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.3 2.7 5.5 1.6 0.1 -1.6 1.2 0.6 -1.8 -1.9 -1.3 1.8 -1.0 -0.2 2.1 2.1 1.6 1.8 -2.0 -1.5 -1.9 -1.9 -1.2 -2.0 -2.1 -2.0 0.3 -1.4 -1.9 -1.2 -1.4 -1.9 -2.3 -1.4 -1.9 -2.0
Whole body water mass 1.3 7.2 41.3 3.0 5.9 0.6 3.6 6.2 -1.8 -0.4 -0.8 2.4 0.4 0.7 0.3 3.0 -4.8 -5.8 0.3 -0.1 0.2 -0.9 0.1 -0.1 2.7 -1.3 6.4 -0.4 0.4 -0.3 -1.5 -0.1 1.9 -1.7 -0.1 1.8
Leg predicted mass (right) 1.4 7.2 40.2 3.5 5.8 -0.5 3.9 6.1 -2.4 -1.2 -1.8 3.0 -0.5 0.3 1.2 3.6 -3.8 -4.8 -0.5 -0.9 -0.5 -1.6 -0.6 -1.0 1.8 -1.9 6.3 -1.4 -0.3 -0.9 -2.2 -0.9 0.8 -2.3 -0.8 0.9
Arm fat mass (left) 1.0 4.0 16.4 2.6 3.5 -1.5 1.9 4.0 -2.1 -1.9 -2.9 2.3 0.3 -0.5 2.1 2.9 -0.6 -1.8 -1.2 -1.7 -0.9 -1.7 -1.4 -1.2 0.0 -2.0 4.1 -1.8 -1.2 -2.0 -2.5 -0.4 0.1 -1.8 -1.4 -0.4
Number of self-reported non-cancer illnesses 1.3 2.2 5.0 1.2 0.8 -2.0 0.6 0.1 -1.4 -1.7 -2.2 1.2 -1.6 -1.0 1.6 0.2 1.6 0.9 -1.5 -2.0 -1.9 -1.4 -1.8 -1.9 -1.9 -1.7 -0.4 -1.1 -1.7 -1.4 -1.6 -1.5 -1.7 -1.0 -1.3 -1.4
Average weekly champagne plus white wine intake 0.4 0.5 2.7 0.6 1.3 1.4 0.8 1.2 -0.2 0.1 0.9 0.5 0.2 0.3 -0.4 0.8 -1.4 -1.3 0.3 0.4 0.4 -0.0 0.5 0.1 0.9 -0.2 1.6 0.4 0.3 0.6 -0.2 0.6 0.2 -0.3 0.6 0.5
Miserableness 0.3 0.5 3.2 0.9 1.3 -0.6 0.5 0.8 -0.7 -0.5 -0.6 0.8 0.5 0.8 0.4 0.4 -0.3 -0.7 -0.5 -0.3 -0.3 -0.6 -0.0 -0.4 0.1 -0.9 1.8 -0.8 -0.2 -0.6 -0.6 -0.4 0.0 -0.9 -0.8 -0.3
Guilty feelings 1.4 2.1 4.5 1.2 -0.0 -2.0 0.9 -0.4 -1.4 -1.6 -1.7 1.3 -1.9 -1.1 1.7 0.6 1.6 1.0 -1.6 -1.6 -1.5 -1.5 -1.6 -1.6 -1.7 -1.1 -0.2 -2.1 -1.4 -1.3 -1.1 -2.0 -1.8 -0.9 -1.5 -1.5
Wears glasses or contact lenses 2.6 3.0 6.2 -1.9 -0.8 1.9 -1.0 -1.4 1.9 2.1 2.1 -1.8 1.2 2.5 -2.3 -1.2 -1.2 -0.4 1.7 2.2 2.0 1.9 2.3 1.7 1.7 1.5 -0.9 2.1 1.9 2.1 1.9 1.4 1.1 1.7 1.7 1.5
Ever taken oral contraceptive pill 2.7 3.0 5.8 1.9 1.8 -2.3 2.2 1.2 -1.9 -1.8 -2.2 1.7 -1.7 -0.9 2.1 1.6 0.7 -0.3 -1.5 -2.3 -1.9 -1.7 -2.4 -2.0 -1.4 -1.7 1.0 -2.1 -1.8 -1.8 -2.0 -1.6 -1.3 -1.4 -1.3 -1.0
Hearing aid user 1.9 2.1 3.7 -1.6 -1.0 1.7 -1.7 -0.3 1.7 1.6 1.5 -1.7 1.2 1.1 -1.3 -1.2 -0.7 -0.5 1.8 1.4 1.9 1.8 1.5 1.4 1.6 1.2 -0.3 1.3 1.6 1.5 1.0 1.9 1.5 1.9 1.8 1.7
Mother’s age at death 1.6 2.0 6.5 -1.4 -1.3 1.8 -1.8 -1.0 1.4 1.5 2.5 -1.3 1.0 1.6 -1.5 -0.8 -1.0 -0.4 1.4 1.7 1.1 1.4 2.0 1.0 0.9 1.0 -1.0 1.9 1.3 2.2 1.6 1.0 0.8 1.6 1.3 1.1
Financial situation satisfaction 1.1 1.3 2.6 1.0 0.7 -1.6 0.6 0.2 -1.1 -1.2 -1.4 1.1 -0.9 -1.1 1.5 1.4 0.8 0.6 -1.2 -1.1 -1.4 -1.2 -1.0 -1.3 -1.4 -1.2 0.1 -1.3 -1.1 -1.0 -0.9 -1.6 -1.2 -1.1 -1.4 -1.3
Tinnitus: Yes, now most or all of the time 2.3 2.6 6.0 -1.7 -0.8 1.4 -1.8 -0.8 1.9 1.9 1.4 -1.7 0.5 1.8 -1.8 -2.5 -1.1 -0.9 2.0 1.4 1.9 1.9 1.6 1.2 1.8 1.2 -0.6 1.9 1.7 1.9 1.2 1.7 1.4 1.9 2.0 2.0
Commuting to job workplace: Public transport 1.3 1.5 6.9 -1.7 -2.6 -0.3 -1.9 -2.3 1.3 0.6 0.2 -1.6 0.4 -1.5 -0.3 -1.2 1.5 2.0 0.6 0.4 0.4 1.0 0.6 0.7 -0.5 0.9 -2.6 0.7 0.4 0.6 1.1 0.5 0.3 1.8 0.4 0.2
Eye problems/disorders: Glaucoma 0.1 0.1 0.4 0.0 0.3 -0.0 -0.1 0.5 0.0 -0.0 -0.3 0.0 -0.5 0.3 0.1 0.1 0.2 0.2 -0.1 -0.4 -0.1 0.0 -0.4 -0.3 0.1 -0.4 0.3 -0.2 -0.3 0.2 -0.2 0.1 -0.3 -0.6 0.1 -0.2
Medication: Blood pressure 0.1 0.2 2.6 -0.3 -0.2 -0.1 -0.8 -0.3 0.2 0.1 -0.4 -0.3 1.6 -0.4 0.0 -1.0 0.4 0.4 0.1 -0.3 -0.3 0.1 -0.2 0.2 -0.3 -0.2 -0.2 0.5 -0.1 -0.8 -0.3 0.4 0.9 0.4 -0.2 0.3
Pain type(s) experienced in last month: Hip pain 0.1 0.2 0.7 0.4 -0.3 -0.5 -0.1 -0.1 -0.5 -0.3 -0.2 0.4 0.9 0.1 0.4 0.1 0.6 0.6 -0.6 -0.1 -0.5 -0.6 -0.4 0.3 -0.6 0.3 -0.1 -0.6 -0.4 -0.5 0.1 -0.1 0.0 -0.2 -0.6 -0.5
Supplements: Fish oil (including cod liver oil) 0.2 0.2 2.2 -0.2 -0.3 0.6 -0.4 -0.5 0.2 0.1 0.7 -0.1 1.5 0.5 -0.6 -0.7 0.4 0.7 -0.0 0.4 0.3 0.1 0.8 0.5 0.1 0.1 0.0 0.8 0.2 0.2 0.2 0.8 0.1 -0.1 -0.1 -0.2
High cholesterol (Self-reported) 0.6 1.0 3.2 1.0 0.9 -1.1 0.2 0.5 -1.1 -1.0 -1.3 1.0 1.7 -1.4 1.1 0.9 0.5 0.0 -1.0 -0.9 -1.4 -1.0 -0.5 -0.5 -1.1 -1.2 0.7 -0.3 -0.8 -1.5 -1.1 -0.8 0.4 -0.9 -1.8 -0.8
Medication: Bendroflumethiazide 0.5 0.7 1.7 1.0 0.7 -0.9 1.3 0.5 -1.0 -0.9 -1.2 1.0 -0.6 -0.8 0.7 0.3 0.1 -0.3 -0.7 -1.0 -1.1 -0.9 -1.0 -1.0 -0.6 -1.1 0.6 -0.8 -0.8 -1.0 -1.0 -1.1 -0.5 -0.8 -0.9 -0.5
Medication: Paracetamol 1.2 1.9 3.9 1.3 0.7 -1.2 0.9 0.4 -1.6 -1.5 -1.1 1.4 0.7 -1.1 1.9 1.4 1.6 1.5 -1.9 -1.3 -1.7 -1.7 -0.8 -1.1 -1.8 -1.4 0.3 -0.7 -1.5 -1.5 -1.2 -1.0 -1.2 -1.5 -2.0 -1.8
Medication: Lisinopril 0.1 0.1 0.6 0.3 0.3 -0.1 0.4 0.0 -0.3 -0.1 -0.3 0.3 0.8 0.3 -0.2 0.2 -0.4 -0.3 -0.2 0.2 -0.2 -0.2 0.4 -0.0 0.0 -0.4 0.5 0.2 0.1 -0.2 0.0 -0.4 0.2 -0.2 -0.5 -0.0
Medication: Atorvastatin 0.5 0.6 2.2 0.8 0.9 -0.8 0.2 0.3 -0.9 -1.0 -1.5 0.8 -0.9 -1.1 0.9 0.2 0.3 -0.3 -0.6 -1.1 -1.0 -0.7 -1.0 -1.0 -0.7 -0.9 -0.1 -0.4 -0.8 -1.0 -0.8 -1.2 -0.6 -0.2 -0.8 -0.2
Illnesses of father: High blood pressure 0.2 0.3 2.3 0.6 1.0 0.1 0.1 1.0 -0.4 -0.5 -0.7 0.5 0.8 -0.2 0.6 0.0 0.1 0.1 -0.5 -0.3 -0.0 -0.4 -0.1 -0.2 -0.0 -0.6 1.5 -0.5 -0.2 -0.6 -0.7 0.5 0.2 -0.6 -0.5 -0.3
Alcohol drinker status: Never 0.4 0.4 2.4 0.1 0.5 1.1 1.0 0.2 0.1 0.5 1.5 0.0 0.1 1.6 -0.8 0.1 -1.3 -1.2 0.3 0.6 0.3 0.2 0.2 0.3 0.7 0.3 0.6 -0.1 0.4 0.5 0.4 -0.3 0.1 -0.8 0.1 0.0
Ever smoked 1.2 2.2 6.3 1.0 0.5 -2.5 0.1 0.1 -1.2 -1.6 -2.2 0.9 -1.9 -1.5 1.8 0.9 1.9 0.9 -1.2 -2.2 -1.6 -1.3 -2.1 -1.6 -1.8 -1.0 -0.5 -2.2 -1.5 -1.7 -1.5 -1.4 -1.3 -0.4 -1.2 -1.1
Basal metabolic rate 1.2 6.7 39.4 3.0 5.7 0.3 3.5 6.1 -1.8 -0.6 -1.2 2.5 0.3 0.5 0.6 3.1 -4.3 -5.4 0.2 -0.4 0.1 -1.0 -0.1 -0.3 2.4 -1.4 6.3 -0.7 0.2 -0.6 -1.8 -0.1 1.7 -1.7 -0.2 1.6
Leg fat percentage (left) 0.8 2.9 7.8 2.0 2.4 -1.4 1.0 2.6 -1.8 -1.8 -2.8 1.7 1.3 -0.4 2.0 1.9 0.6 -0.7 -1.2 -2.0 -1.1 -1.5 -1.8 -1.1 -0.7 -1.9 2.6 -1.6 -1.5 -2.8 -2.7 -0.2 0.3 -1.5 -1.7 -0.7
Arm fat-free mass (left) 1.4 6.9 40.7 2.7 5.9 0.8 3.1 6.0 -1.6 -0.3 -0.8 2.2 1.4 0.9 0.2 2.8 -4.7 -5.7 0.5 -0.0 0.3 -0.7 0.3 0.2 2.7 -1.2 6.4 -0.1 0.6 -0.5 -1.5 0.3 2.5 -1.5 -0.1 2.0
Number of operations (self-reported) 1.0 1.5 7.0 1.5 1.5 -0.7 1.9 1.3 -1.3 -0.8 -1.0 1.3 -2.6 -0.1 0.6 0.9 -1.2 -1.9 -0.5 -1.1 -1.0 -0.9 -1.9 -1.0 0.1 -0.4 1.0 -1.6 -0.9 -0.6 -0.7 -1.7 -0.6 -1.6 -0.5 -0.2
Average weekly beer plus cider intake 0.2 0.2 1.2 -0.2 -0.3 -0.8 -0.9 -0.5 0.1 -0.2 -0.6 -0.2 -0.5 -0.1 0.5 -0.3 1.1 0.9 -0.2 -0.6 -0.1 0.0 -0.3 -0.7 -0.5 -0.6 -0.7 0.1 -0.3 -0.5 -0.6 -0.2 -0.5 0.3 -0.1 -0.2
Irritability 0.7 1.3 2.6 1.3 1.6 -0.9 1.4 1.4 -1.3 -1.1 -1.1 1.3 -0.6 -0.8 1.3 1.0 0.3 -0.3 -1.0 -1.3 -1.2 -1.1 -1.0 -1.4 -0.8 -1.6 1.2 -0.7 -1.2 -0.9 -1.4 -1.0 -0.9 -1.2 -1.0 -0.8
Risk taking 6.1 9.0 17.8 3.1 2.2 -3.2 3.6 2.2 -3.2 -3.5 -4.1 3.1 -1.7 -1.5 3.1 2.5 2.7 1.6 -3.2 -3.6 -2.9 -3.3 -3.6 -3.0 -2.7 -3.2 1.6 -3.3 -3.2 -4.2 -3.6 -2.4 -2.6 -2.9 -3.1 -2.7
Ever had prostate specific antigen (PSA) test 2.8 3.3 5.8 -2.2 -2.2 1.1 -1.6 -2.2 2.1 2.1 1.6 -2.0 1.2 1.6 -1.6 -2.0 -0.3 0.6 1.6 2.3 2.0 1.9 2.3 2.2 1.3 2.3 -1.4 1.5 1.9 2.2 2.4 1.9 1.3 1.9 1.6 1.1
Fractured/broken bones in last 5 years 1.6 2.0 7.7 -1.7 -1.1 0.9 -1.7 -1.3 1.8 1.7 1.5 -1.7 -1.4 1.1 -1.2 -2.8 -0.5 -0.2 1.8 0.8 1.4 1.7 0.9 0.7 1.3 1.3 -1.3 1.2 1.2 2.0 1.0 1.1 0.5 1.4 2.2 1.5
Age started oral contraceptive pill 0.2 0.2 3.2 0.6 0.9 0.0 0.5 0.4 -0.4 -0.2 -0.2 0.5 0.3 1.8 0.4 0.2 -0.4 -0.9 -0.0 -0.4 -0.3 -0.3 -0.4 -0.2 0.1 -0.4 0.7 0.0 -0.3 -0.2 -0.4 0.2 0.3 -0.5 -0.0 0.0
Diastolic blood pressure, automated reading 0.5 1.5 4.6 1.4 0.8 -0.8 2.1 0.3 -1.4 -1.5 -1.1 1.5 0.6 -1.0 0.9 0.9 0.8 0.6 -1.7 -0.8 -1.4 -1.5 -0.6 -0.8 -1.4 -1.2 0.6 -0.6 -1.3 -1.3 -1.0 -1.1 -1.0 -1.7 -2.0 -1.8
Ever depressed for a whole week 0.7 0.9 2.2 1.0 1.4 -0.6 -0.1 1.1 -0.9 -1.0 -1.2 1.0 0.3 1.5 1.2 1.3 1.0 0.9 -1.1 -0.7 -0.3 -0.9 -0.2 -0.8 -0.5 -1.3 1.5 -0.5 -0.6 -1.0 -1.3 0.3 -0.8 -0.9 -0.6 -0.8
Unable to work because of sickness or disability 1.3 1.7 5.7 1.5 1.0 -1.5 1.2 0.4 -1.5 -1.2 -1.1 1.5 -2.4 -1.3 0.9 0.7 0.1 -0.3 -1.3 -1.3 -1.4 -1.4 -1.5 -1.7 -1.0 -1.4 0.3 -1.2 -1.4 -1.1 -1.1 -2.2 -1.8 -1.5 -1.1 -1.1
Commuting to job workplace: Cycle 1.7 2.1 4.7 -1.8 -1.8 0.2 -1.7 -1.2 1.6 1.6 0.6 -1.7 0.7 0.3 -1.1 -0.5 -0.4 1.0 1.3 1.9 1.3 1.4 1.8 1.7 0.9 1.9 -1.6 1.6 1.5 1.8 2.1 1.4 0.9 2.2 1.7 1.4
Myopia 0.7 1.0 3.8 -0.4 0.2 1.1 -0.8 0.2 0.7 1.0 1.4 -0.5 -0.2 1.6 -1.2 0.6 -2.0 -1.6 1.0 1.3 0.8 0.8 1.2 0.8 1.3 0.8 0.4 1.0 1.0 1.7 1.3 0.3 0.6 0.2 0.8 0.9
Vascular/heart problems diagnosed by doctor 0.7 1.9 4.1 -1.6 -1.2 1.6 -2.0 -1.3 1.6 1.5 1.8 -1.6 -0.1 1.2 -1.3 -0.7 -0.6 -0.2 1.5 1.5 1.8 1.6 1.4 1.3 1.5 1.5 -1.0 1.2 1.6 1.5 1.4 1.3 0.8 1.3 1.8 1.2
Cholesterol lowering medication 1.5 2.2 5.2 1.6 1.3 -1.6 0.3 1.1 -1.6 -1.5 -1.9 1.6 -0.0 -0.5 2.0 1.1 1.0 0.4 -1.5 -2.0 -1.8 -1.6 -1.6 -1.7 -1.3 -2.1 1.2 -1.1 -1.6 -2.0 -2.3 -1.2 -0.7 -1.5 -1.7 -1.1
Medication: Omeprazole (e.g. Zanprol) 0.2 0.2 1.1 0.1 0.7 0.7 -0.7 0.4 0.1 0.2 0.3 0.1 -0.6 0.5 -0.3 -0.8 -1.0 -0.9 0.2 0.0 0.1 0.1 0.3 -0.2 0.6 -0.3 0.7 0.6 0.3 0.5 -0.1 -0.2 0.0 -0.4 0.4 0.6
Pain experienced in last month 0.1 0.1 0.6 -0.5 -0.8 0.4 0.3 -0.7 0.4 0.3 0.5 -0.4 -0.6 0.0 -0.5 0.1 0.1 0.3 0.3 0.3 0.3 0.4 0.2 -0.1 0.0 0.1 -0.7 0.1 0.2 0.5 0.4 -0.1 -0.3 0.6 0.3 0.1
Supplements: Calcium 0.4 0.4 2.7 -0.7 -0.8 0.7 -1.6 -0.5 0.7 0.4 0.9 -0.7 -0.7 1.2 -0.4 -0.1 0.7 0.6 0.5 0.3 0.8 0.6 0.4 0.1 0.2 0.3 -0.5 0.1 0.3 0.9 0.2 0.8 -0.5 0.5 0.8 -0.1
Basal cell carcinoma (self-reported) 1.8 2.1 7.5 2.1 2.3 -0.1 1.4 2.7 -1.8 -1.3 -0.7 2.0 -0.3 0.3 0.9 1.6 -0.4 -0.6 -1.3 -1.3 -1.1 -1.6 -1.3 -1.3 -0.3 -1.7 2.6 -1.5 -1.4 -1.3 -1.7 -1.2 -0.9 -2.1 -1.2 -0.9
Heart attack/myocardial infarction (self-reported) 0.4 0.6 2.5 1.0 1.2 -0.8 0.7 1.3 -0.8 -0.4 -0.9 1.0 1.5 0.2 0.6 1.3 -0.5 -0.4 -0.6 0.0 -0.5 -0.7 0.3 0.1 -0.2 -0.5 1.6 0.0 -0.3 -0.3 -0.3 0.1 0.4 -0.8 -0.9 -0.3
Deep venous thrombosis (DVT) (self-reported) 1.5 2.0 11.2 1.7 3.0 -0.1 1.5 3.1 -1.1 -0.4 -0.7 1.5 0.0 1.1 0.3 1.4 -1.8 -2.4 -0.3 -0.7 -0.3 -0.8 -1.1 -0.7 0.9 -1.2 3.4 -0.9 -0.6 -1.1 -1.5 -0.3 0.3 -2.0 -0.4 0.1
Heart disease (siblings) 0.1 0.2 1.9 0.3 0.2 -0.6 0.2 0.7 -0.2 -0.2 -0.5 0.3 0.2 -1.4 0.4 0.3 0.1 0.1 -0.2 -0.3 -0.4 -0.3 -0.1 -0.3 -0.2 -0.6 0.4 0.2 -0.4 -0.1 -0.3 0.0 -0.0 -0.3 -0.3 -0.2
Alcohol drinker status: Previous 0.6 0.7 1.6 1.1 1.1 -0.7 1.1 0.8 -1.0 -0.9 -1.1 1.0 0.4 0.1 0.8 0.8 -0.5 -1.0 -0.7 -0.6 -1.1 -0.9 -1.0 -0.6 -0.5 -0.9 0.7 -0.5 -0.9 -1.3 -0.6 -1.1 -0.1 -1.1 -1.1 -0.5
Pack years of smoking 0.3 0.4 1.5 0.2 -0.1 -0.9 0.2 -0.3 -0.3 -0.4 -0.7 0.2 -1.0 -1.2 0.4 -0.0 0.8 0.1 -0.4 -0.8 -0.4 -0.3 -1.0 -0.9 -0.6 -0.8 -0.6 -0.6 -0.6 -1.0 -0.8 -0.8 -0.7 0.1 -0.3 -0.3
Impedance of whole body 1.3 6.6 30.7 -3.5 -5.5 1.1 -3.9 -4.5 2.7 1.6 2.2 -3.1 0.9 1.0 -1.1 -3.1 3.3 4.6 1.0 1.6 1.9 2.0 1.8 1.6 -0.5 2.3 -4.2 1.1 1.2 2.0 2.3 2.5 -0.3 2.5 1.7 -0.3
Leg fat mass (left) 1.2 4.7 19.5 2.8 4.0 -1.3 2.2 4.4 -2.2 -1.9 -2.9 2.4 0.9 -0.3 2.0 2.9 -0.9 -2.4 -1.1 -1.9 -1.0 -1.8 -1.6 -1.2 0.1 -2.2 4.4 -1.7 -1.3 -2.5 -2.9 -0.4 0.6 -2.0 -1.6 -0.3
Arm predicted mass (left) 1.3 6.4 37.6 2.5 5.5 1.0 2.8 5.7 -1.3 -0.1 -0.6 1.9 1.3 1.1 -0.0 2.6 -4.7 -5.6 0.7 0.2 0.5 -0.5 0.4 0.4 2.9 -0.9 6.1 0.0 0.7 -0.2 -1.3 0.5 2.6 -1.3 0.1 2.1