[Hub]/) : Traits : Hayfever, allergic rhinitis or eczema :

chr16:10,325,245-12,138,068

Best TWAS P=2.56e-27 · Best GWAS P=1.16e-34 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum DEXI 0.17 0.02 enet 27 0.03 1.3e-02 -10.519 -7.5 7.7e-14 0.53 0.08 0.84 FALSE
2 GTEx Adipose Visceral Omentum RP11-876N24.5 0.11 0.08 lasso 2 0.10 6.0e-06 -9.763 -9.6 8.1e-22 0.68 0.06 0.92 FALSE
3 GTEx Brain Putamen basal ganglia RMI2 0.48 0.31 lasso 9 0.40 1.7e-10 -2.535 -5.9 2.9e-09 0.34 0.69 0.03 TRUE
4 GTEx Breast Mammary Tissue DEXI 0.12 0.07 enet 14 0.08 6.9e-05 -8.865 -8.7 4.4e-18 0.72 0.06 0.89 FALSE
5 GTEx Breast Mammary Tissue RP11-876N24.5 0.15 0.11 enet 19 0.12 1.4e-06 -8.865 -10.8 3.8e-27 0.73 0.29 0.69 TRUE
6 GTEx Breast Mammary Tissue (Male) DEXI 0.18 0.04 lasso 3 -0.01 4.9e-01 -6.399 -6.8 8.8e-12 0.63 0.03 0.64 FALSE
7 GTEx Breast Mammary Tissue (Male) RP11-876N24.5 0.16 0.24 lasso 2 0.21 1.5e-05 -6.328 -7.0 2.1e-12 0.36 0.07 0.22 FALSE
8 GTEx Breast Mammary Tissue (Female) DEXI 0.13 0.06 lasso 2 0.04 2.0e-02 -10.257 -10.2 3.0e-24 0.79 0.05 0.52 FALSE
9 GTEx Breast Mammary Tissue (Female) RP11-876N24.5 0.22 0.14 enet 11 0.13 1.0e-04 -9.872 -10.6 4.4e-26 0.77 0.14 0.75 TRUE
10 GTEx Cells Transformed fibroblasts DEXI 0.12 0.05 lasso 5 0.08 9.6e-07 -6.156 -8.5 1.4e-17 0.72 0.18 0.82 TRUE
11 GTEx Cells Transformed fibroblasts RP11-876N24.4 0.12 0.04 lasso 5 0.08 2.1e-06 -6.156 -8.6 1.2e-17 0.73 0.18 0.82 FALSE
12 GTEx Nerve Tibial DEXI 0.11 0.05 enet 7 0.07 1.7e-05 -8.865 -10.7 1.4e-26 0.81 0.64 0.27 FALSE
13 GTEx Pancreas DEXI 0.13 0.06 lasso 4 0.07 5.7e-04 -8.844 -8.9 6.8e-19 0.67 0.18 0.68 FALSE
14 GTEx Pancreas RP11-876N24.4 0.11 0.05 lasso 3 0.04 8.6e-03 -8.844 -8.8 1.0e-18 0.67 0.15 0.67 FALSE
15 GTEx Skin Sun Exposed Lower leg DEXI 0.05 0.06 lasso 2 0.03 7.8e-04 -8.844 -8.6 1.2e-17 0.65 0.71 0.20 FALSE
16 GTEx Testis CLEC16A 0.15 0.00 enet 20 0.01 1.2e-01 -9.454 -10.0 9.5e-24 0.71 0.02 0.92 FALSE
17 GTEx Testis DEXI 0.21 0.11 lasso 3 0.08 2.1e-04 -10.888 -9.3 9.7e-21 0.68 0.29 0.32 FALSE
18 GTEx Testis RP11-876N24.4 0.21 0.06 lasso 5 0.07 6.0e-04 -10.888 -10.0 2.2e-23 0.70 0.22 0.30 FALSE
19 GTEx Thyroid DEXI 0.08 0.00 enet 18 0.03 1.8e-03 -8.844 -7.0 2.4e-12 0.53 0.18 0.65 FALSE
20 GTEx Thyroid RP11-876N24.4 0.06 0.00 enet 17 0.02 1.5e-02 1.575 -5.7 1.1e-08 0.43 0.18 0.32 FALSE
21 GTEx Thyroid RP11-396B14.2 0.12 0.01 lasso 6 0.01 4.0e-02 -11.084 10.8 2.6e-27 -0.80 0.01 0.96 TRUE
22 ROSMAP Brain Pre-frontal Cortex DEXI 0.12 0.12 lasso 6 0.13 5.9e-16 -8.263 -9.0 2.1e-19 0.70 1.00 0.00 FALSE
23 YFS Blood CLEC16A 0.08 0.01 bslmm 627 0.03 1.2e-09 -0.045 5.4 6.8e-08 -0.17 0.93 0.00 TRUE
24 YFS Blood DEXI 0.11 0.15 enet 29 0.16 2.6e-51 -8.263 -8.2 3.5e-16 0.66 1.00 0.00 FALSE
25 The Cancer Genome Atlas Breast Invasive Carcinoma DEXI 0.04 0.02 blup 49 0.04 8.6e-08 -9.763 -8.7 3.6e-18 0.66 0.03 0.97 TRUE
26 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DEXI 0.05 0.02 lasso 4 0.03 1.7e-04 -6.283 -6.4 1.3e-10 0.64 0.02 0.84 FALSE
27 The Cancer Genome Atlas Skin Cutaneous Melanoma DEXI 0.20 0.00 blup 49 0.06 1.3e-02 5.953 -5.5 5.1e-08 0.42 0.01 0.10 FALSE
28 The Cancer Genome Atlas Thyroid Carcinoma CLEC16A 0.14 0.06 lasso 4 0.09 6.8e-09 -8.865 6.5 5.7e-11 -0.63 0.22 0.77 FALSE