Best TWAS P=3.6e-08 · Best GWAS P=1.07e-07 conditioned to 0.459
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | EPHA2 | 0.19 | 0.13 | enet | 29 | 0.14 | 6.7e-10 | -4.7 | 5.2 | 2.3e-07 | -0.74 | 0.03 | 0.96 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | SZRD1 | 0.04 | 0.02 | lasso | 7 | 0.02 | 3.6e-03 | 5.1 | 5.2 | 2.3e-07 | -0.80 | 0.03 | 0.93 | FALSE |
| 3 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | C1orf89 | 0.09 | 0.02 | blup | 44 | 0.03 | 1.4e-02 | -5.3 | -5.5 | 3.6e-08 | 0.91 | 0.00 | 0.77 | TRUE |
| 4 | The Cancer Genome Atlas | Glioblastoma Multiforme | C1orf89 | 0.17 | 0.07 | lasso | 2 | 0.08 | 1.5e-03 | -5.3 | -5.2 | 1.5e-07 | 0.99 | 0.00 | 0.93 | FALSE |