TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Cholesterol lowering medication
:
←
→
chr1:26,327,671-27,882,335
Best TWAS P=1.78e-08 · Best GWAS P=3.29e-06 conditioned to 0.525
26.4M
26.6M
26.8M
27M
27.2M
27.4M
27.6M
27.8M
0
1
2
3
4
5
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Esophagus Muscularis
PIGV
0.09
0.07
enet
25
0.13
3.4e-08
4.4
-5.6
1.8e-08
-0.88
0.03
0.95
TRUE
3
NTR
Blood
ARID1A
0.03
0.03
enet
20
0.03
7.8e-11
4.5
-5.4
5.8e-08
-0.95
0.03
0.95
FALSE
2
METSIM
Adipose
ZDHHC18
0.04
0.03
lasso
2
0.04
3.8e-06
4.4
5.4
6.2e-08
0.83
0.03
0.95
FALSE