TWAS hub - C1orf89

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Breast Invasive Carcinoma	0.0444	0.0216	2.6e-05	0.014	0.024	0.022	NA	0.018	5.1e-04	9.7e-06	2.1e-05	NA	9.3e-05
2	TCGA	Cervical Squamous Cell Carcinoma	0.0910	0.0570	7.2e-03	0.016	0.029	0.019	NA	0.026	5.4e-02	1.4e-02	3.9e-02	NA	1.9e-02
3	TCGA	Colon Adenocarcinoma	0.1070	0.0450	6.0e-07	0.045	0.100	0.086	NA	0.071	1.3e-03	2.3e-06	1.2e-05	NA	6.2e-05
4	TCGA	Glioblastoma Multiforme	0.1670	0.0870	4.9e-04	0.067	0.078	0.050	NA	0.085	4.5e-03	2.2e-03	1.2e-02	NA	1.5e-03
5	TCGA	Head and Neck Squamous Cell Carcinoma	0.0306	0.0167	7.9e-04	0.025	0.022	0.030	NA	0.026	7.1e-04	1.4e-03	2.2e-04	NA	5.6e-04
6	TCGA	Kidney Renal Clear Cell Carcinoma	0.0969	0.0378	1.2e-11	0.099	0.105	0.085	NA	0.091	3.0e-11	8.1e-12	7.5e-10	NA	2.0e-10
7	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0620	0.0370	1.8e-03	0.037	0.037	0.027	NA	0.030	3.3e-03	3.3e-03	1.1e-02	NA	8.0e-03
8	TCGA	Brain Lower Grade Glioma	0.0964	0.0383	1.4e-13	0.135	0.117	0.116	NA	0.121	4.2e-15	3.5e-13	4.5e-13	NA	1.3e-13
9	TCGA	Liver Hepatocellular Carcinoma	0.1040	0.0530	1.4e-05	0.072	0.114	0.075	NA	0.087	2.7e-04	5.2e-06	2.1e-04	NA	6.6e-05
10	TCGA	Lung Adenocarcinoma	0.0286	0.0165	5.3e-04	0.043	0.031	0.028	NA	0.034	8.9e-06	1.4e-04	2.8e-04	NA	7.4e-05
11	TCGA	Pancreatic Adenocarcinoma	0.0970	0.0520	2.2e-04	0.140	0.054	0.102	NA	0.122	1.7e-06	2.8e-03	4.9e-05	NA	8.3e-06
12	TCGA	Prostate Adenocarcinoma	0.1021	0.0486	5.8e-09	0.110	0.090	0.108	NA	0.105	1.5e-11	1.3e-09	2.2e-11	NA	4.1e-11
13	TCGA	Stomach Adenocarcinoma	0.0760	0.0490	7.3e-03	0.027	0.010	-0.003	NA	-0.001	4.5e-03	5.5e-02	6.4e-01	NA	4.0e-01
14	TCGA	Testicular Germ Cell Tumors	0.1320	0.0770	2.1e-03	0.041	0.048	0.045	NA	0.050	1.4e-02	8.3e-03	1.1e-02	NA	7.1e-03
15	TCGA	Thyroid Carcinoma	0.0770	0.0480	4.3e-05	0.025	0.027	0.011	NA	0.012	1.5e-03	1.1e-03	2.5e-02	NA	2.4e-02
16	TCGA	Uterine Corpus Endometrial Carcinoma	0.2980	0.1250	3.8e-04	0.020	0.060	0.014	NA	0.036	9.2e-02	9.0e-03	1.3e-01	NA	3.6e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Cholesterol lowering medication	12.1	17.8	30.4	-3.4	-5.5	-4.7	-5.2	-4.6	-4.9	-4.4	-4.4	-3.6	-4.1	-4.0	-4.3	-3.7	-5.0	-2.5	-0.7
Neck or shoulder pain in last month	10.2	14.4	20.6	-3.6	-2.7	-4.3	-3.5	-4.0	-4.0	-3.6	-4.1	-4.3	-4.1	-4.3	-4.3	-3.1	-4.1	-4.5	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	7.2	16.6	27.2	1.5	3.5	3.9	4.3	5.2	3.8	4.8	4.6	5.0	4.5	4.5	4.2	2.6	3.8	4.6	-2.3
Lung FEV1/FVC ratio	6.9	34.8	46.9	4.7	5.5	6.6	5.5	6.8	5.9	6.6	5.9	6.8	5.8	5.8	5.8	6.8	6.4	5.7	-1.3
Chronic bronchitis/emphysema (mother)	5.9	6.9	9.5	1.8	2.5	2.8	3.0	3.1	2.7	2.8	2.9	2.8	2.8	2.9	2.8	2.1	2.8	2.4	0.0
Medication: Lansoprazole	5.3	6.0	9.6	-1.4	-1.9	-2.6	-2.6	-3.0	-2.6	-2.6	-2.6	-3.0	-2.5	-2.6	-2.6	-1.5	-2.7	-3.1	0.3
High cholesterol (Self-reported)	5.3	9.3	13.5	-2.9	-3.5	-3.4	-3.6	-3.2	-3.7	-2.7	-3.2	-2.6	-3.0	-3.1	-3.2	-2.5	-3.6	-2.4	-1.4
Medication: Simvastatin	5.0	7.4	12.7	-2.2	-3.5	-3.1	-3.6	-2.9	-3.4	-2.7	-2.7	-2.3	-2.4	-2.4	-2.5	-2.3	-3.6	-1.6	-0.9
Medication for cholesterol	4.8	7.3	12.7	2.7	3.6	3.0	3.3	2.6	3.2	2.6	2.8	2.0	2.7	2.6	2.9	2.5	3.1	1.2	1.1
High blood pressure (siblings)	4.6	6.6	9.3	-1.8	-2.0	-2.7	-2.9	-2.9	-2.8	-3.0	-3.0	-2.9	-2.9	-2.8	-2.7	-1.5	-2.6	-2.6	0.5
Heel bone mineral density (BMD) T-score, automated (left)	4.5	10.2	16.7	1.1	2.6	3.0	3.2	4.1	2.9	4.0	3.7	4.0	3.5	3.6	3.3	2.0	2.7	3.6	-2.3
Average weekly red wine intake	4.3	6.3	9.7	1.5	2.5	2.5	3.0	2.8	2.8	2.9	3.1	2.4	3.1	2.9	2.9	1.2	2.3	2.1	-0.4
Past tobacco smoking	4.1	7.6	10.6	-2.4	-3.1	-2.9	-3.0	-2.6	-3.1	-2.5	-3.1	-2.4	-3.1	-3.2	-3.2	-2.3	-3.0	-2.2	-0.8
Severe depression (siblings)	4.0	4.5	7.3	2.2	1.6	2.6	2.1	2.7	2.4	1.9	2.0	2.3	1.9	1.9	1.9	1.9	2.7	2.5	0.8
Hair/balding pattern: Pattern 3	3.9	5.9	17.9	3.6	2.2	2.9	1.4	1.7	2.8	1.7	2.1	1.9	2.1	2.1	2.2	4.2	2.5	1.7	1.8
Cardiovascular Disease	3.4	11.1	15.5	-2.9	-3.8	-3.7	-3.9	-3.4	-3.8	-3.2	-3.8	-2.9	-3.7	-3.6	-3.6	-3.0	-3.5	-2.5	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	3.4	4.6	7.1	1.8	1.9	2.4	2.1	2.7	2.4	1.9	2.1	2.3	2.0	2.2	2.1	1.7	2.6	2.5	0.8
High blood pressure (mother)	3.2	4.5	6.8	-1.4	-2.2	-2.2	-2.2	-2.6	-2.4	-2.4	-2.3	-2.3	-2.3	-2.3	-2.3	-1.5	-2.2	-2.1	0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.2	3.8	9.2	2.0	3.0	2.2	2.6	1.9	2.4	1.4	1.7	1.0	1.4	1.5	1.7	1.9	2.6	0.6	1.6
Eye problems/disorders: Diabetes related eye disease	3.1	3.4	5.8	1.2	0.9	1.9	1.8	2.1	1.7	2.4	2.1	2.4	2.1	1.9	1.9	1.2	1.8	2.1	-1.1
Systolic Blood Pressure	2.9	14.6	23.4	-1.9	-3.4	-3.8	-4.2	-4.8	-3.7	-4.7	-4.3	-4.4	-4.2	-4.2	-4.0	-2.4	-3.7	-3.9	1.7
LDL Cholesterol	2.8	4.4	6.7	-0.9	-1.8	-2.1	-2.5	-2.4	-2.1	-2.6	-2.5	-2.5	-2.4	-2.4	-2.2	-0.7	-2.2	-2.1	0.8
Lung FVC	2.8	14.0	25.5	-0.9	-2.1	-3.4	-4.4	-4.3	-3.0	-5.0	-4.4	-5.0	-4.3	-4.2	-3.9	-0.7	-3.5	-3.9	3.4
Nervous feelings	2.8	5.3	9.2	-2.4	-3.0	-2.6	-2.7	-2.0	-2.7	-1.7	-2.2	-1.5	-2.1	-2.1	-2.3	-2.5	-2.9	-0.9	-1.8
Ever smoked	2.6	4.6	6.6	2.2	2.4	2.4	2.1	2.0	2.5	1.8	2.3	1.8	2.4	2.4	2.6	1.9	2.2	1.9	0.9
Ever unenthusiastic/disinterested for a whole week	2.5	3.0	6.3	0.9	1.8	1.8	2.5	2.2	2.0	2.0	1.8	1.8	1.7	1.6	1.6	0.6	2.2	1.5	-0.1
Illnesses of mother	2.5	3.0	5.4	0.5	1.9	1.6	2.3	2.2	1.9	2.0	2.0	1.7	1.9	1.9	2.0	-0.1	1.8	1.7	-0.5
Illnesses of siblings	2.3	3.3	5.6	1.2	1.2	1.9	1.9	2.1	1.9	2.4	2.0	2.3	1.9	1.8	1.7	1.3	1.9	1.8	-0.6
Osteoporosis (self-reported)	2.3	2.8	5.3	-1.0	-2.0	-1.8	-1.3	-2.3	-1.7	-2.3	-1.4	-2.1	-1.4	-1.4	-1.5	-2.2	-1.5	-1.3	1.2
Heel T-Score	2.2	17.8	32.7	1.8	2.9	4.2	4.2	5.1	3.6	5.2	4.6	5.7	4.5	4.5	4.1	3.0	4.2	4.9	-2.9
Lung cancer (father)	2.2	2.5	5.6	0.6	0.9	1.5	1.6	1.7	1.3	2.2	1.6	2.4	1.6	1.6	1.4	1.6	1.8	1.5	-1.4
Commuting to job workplace: Walk	2.2	2.4	5.5	-1.2	-2.3	-1.7	-2.4	-1.6	-2.1	-1.5	-1.4	-1.0	-1.2	-1.0	-1.2	-1.1	-2.1	-0.5	-0.9
Body Mass Index (BMI) (2010)	2.1	2.9	6.5	-0.0	1.2	1.3	1.8	2.2	1.2	2.5	1.9	2.2	1.8	1.8	1.6	0.5	1.2	1.6	-2.3
Breastfed as a baby	2.1	2.7	6.1	-2.5	-1.4	-1.9	-1.6	-1.2	-1.9	-1.5	-1.8	-1.1	-1.8	-1.6	-1.7	-1.9	-1.6	-0.9	-1.1
Pack years adult smoking proportion	2.0	3.1	6.6	-1.5	-0.8	-1.8	-1.4	-1.8	-1.7	-1.7	-2.0	-2.1	-2.1	-2.1	-2.1	-1.2	-1.8	-2.6	-0.0
Heart disease (mother)	2.0	2.5	5.1	-0.1	-1.5	-1.4	-1.7	-2.0	-1.4	-2.2	-1.6	-2.0	-1.6	-1.7	-1.6	-0.7	-1.4	-1.3	1.7
Medication: Blood pressure	2.0	3.9	7.0	-2.0	-2.7	-2.3	-2.4	-2.1	-2.4	-1.6	-1.8	-1.5	-1.7	-1.8	-2.0	-1.8	-2.4	-1.1	-1.3
Depression (Nagel 2018)	1.9	2.9	5.6	1.9	1.8	2.0	2.0	2.0	2.1	1.4	1.5	1.4	1.2	1.3	1.4	1.6	2.4	1.5	1.4
Blood Eosinophil Count	1.9	14.9	22.1	1.3	3.3	3.6	4.4	4.7	3.7	4.5	4.6	4.4	4.5	4.7	4.4	1.2	3.6	4.1	-1.7
Ever highly irritable/argumentative for 2 days	1.9	2.3	3.5	1.2	1.7	1.5	1.9	1.6	1.7	1.6	1.8	1.3	1.7	1.7	1.8	0.7	1.7	1.1	0.2
Medication: Ibuprofen (e.g. Nurofen)	1.8	2.3	5.7	-0.5	0.8	0.7	1.1	2.0	0.6	2.0	1.7	1.9	1.9	1.8	1.6	0.4	0.4	2.0	-2.4
Birth weight	1.8	4.0	8.2	0.6	1.1	1.9	1.9	2.6	1.6	2.6	2.1	2.9	2.1	2.1	1.9	1.2	2.0	2.5	-1.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.8	3.8	7.9	-0.5	-1.5	-1.6	-2.5	-1.9	-1.7	-2.8	-2.5	-2.3	-2.4	-2.3	-2.1	-0.6	-1.6	-1.3	1.9
Prospective memory result	1.7	2.1	3.7	1.3	0.4	1.5	1.1	1.3	1.2	1.8	1.8	1.8	1.9	1.8	1.8	1.2	1.3	1.5	-0.6
Medication: Atorvastatin	1.7	2.1	3.4	-0.6	-1.4	-1.4	-1.7	-1.7	-1.3	-1.8	-1.9	-1.5	-1.8	-1.8	-1.7	-0.7	-1.2	-1.3	0.8
Unable to work because of sickness or disability	1.7	2.2	3.8	-1.3	-1.2	-1.5	-0.9	-1.4	-1.1	-1.6	-1.7	-1.6	-1.8	-1.9	-1.8	-1.9	-1.1	-1.4	0.6
Triglycerides	1.6	2.6	4.7	-1.1	-0.7	-1.6	-1.2	-1.7	-1.4	-1.9	-1.8	-2.2	-1.9	-2.0	-1.9	-1.3	-1.5	-2.0	0.5
Smoking status: Previous	1.6	2.4	4.0	1.0	1.5	1.5	1.8	1.4	1.5	1.6	1.9	1.5	1.9	2.0	2.0	1.1	1.6	1.3	-0.1
Leg fat-free mass (right)	1.6	8.3	17.0	-0.1	3.1	2.5	3.6	4.1	2.7	3.6	3.1	3.4	2.9	2.9	2.5	1.4	2.9	2.8	-2.4
Tinnitus: Yes, now most or all of the time	1.6	1.9	3.5	-1.7	-1.9	-1.5	-1.8	-0.9	-1.6	-0.7	-1.4	-0.4	-1.3	-1.3	-1.4	-1.2	-1.8	-0.4	-1.8
Number of treatments/medications taken	1.5	2.7	4.2	-1.5	-1.9	-1.8	-2.0	-1.6	-2.0	-1.5	-1.7	-1.4	-1.6	-1.7	-1.8	-1.0	-2.1	-1.1	-0.8
Other serious medical condition/disability diagnosed by doctor	1.5	2.0	4.9	-1.3	-0.2	-1.6	-0.7	-1.4	-1.1	-1.8	-1.3	-2.2	-1.5	-1.5	-1.5	-1.5	-1.4	-1.7	0.8
Impedance of leg (right)	1.5	7.5	17.0	-1.0	-4.1	-2.9	-3.4	-3.8	-3.1	-3.0	-2.6	-2.5	-2.2	-2.2	-2.0	-2.9	-3.1	-1.8	0.7
High blood pressure	1.5	4.2	9.2	-1.6	-3.0	-2.2	-2.7	-2.1	-2.5	-2.1	-2.4	-1.4	-2.2	-2.1	-2.3	-1.3	-2.0	-0.8	-0.4
Impedance of leg (left)	1.5	7.3	16.7	-0.9	-4.1	-2.9	-3.3	-3.8	-3.0	-3.0	-2.5	-2.6	-2.1	-2.2	-2.0	-2.8	-3.2	-1.8	0.8
Leg predicted mass (right)	1.5	8.1	16.5	-0.1	3.0	2.5	3.5	4.1	2.6	3.6	3.1	3.3	2.8	2.8	2.4	1.4	2.8	2.8	-2.4
Average weekly beer plus cider intake	1.5	2.2	7.4	0.6	-0.3	-0.8	-1.6	-1.5	-0.5	-2.2	-1.6	-2.1	-1.5	-1.5	-1.3	0.6	-0.9	-1.5	2.7
Diastolic blood pressure, automated reading	1.5	4.6	8.8	-0.5	-0.6	-1.5	-1.6	-2.1	-1.2	-2.9	-2.7	-2.9	-2.8	-3.0	-2.6	-0.8	-1.2	-2.4	2.4
Coronary Artery Disease (CAD)	1.4	1.7	3.6	-0.4	-1.1	-1.1	-1.8	-1.9	-1.2	-1.3	-1.4	-1.4	-1.3	-1.5	-1.4	-0.0	-1.5	-1.7	0.1
Leg fat-free mass (left)	1.4	7.3	14.9	-0.5	2.6	2.2	3.3	3.9	2.3	3.5	2.9	3.3	2.7	2.7	2.3	1.0	2.5	2.7	-2.7
Average weekly fortified wine intake	1.4	1.7	4.1	1.1	1.4	1.4	2.0	1.1	1.7	0.9	1.3	0.8	1.1	1.1	1.3	0.3	1.9	0.8	1.1
Leg predicted mass (left)	1.4	7.3	15.0	-0.5	2.7	2.2	3.3	3.9	2.3	3.5	2.9	3.3	2.7	2.7	2.3	1.0	2.5	2.7	-2.7
Medication: Amlodipine	1.4	2.0	4.2	-1.7	-1.6	-1.6	-2.1	-1.0	-1.9	-0.8	-1.3	-0.6	-1.1	-1.0	-1.2	-0.6	-1.9	-0.5	-2.0
Risk taking	1.4	2.0	3.3	1.1	1.8	1.4	1.8	1.6	1.6	1.5	1.6	1.1	1.5	1.6	1.7	0.8	1.5	0.9	0.3
Pack years of smoking	1.4	2.1	5.5	-1.2	-0.4	-1.5	-1.0	-1.6	-1.3	-1.4	-1.5	-1.9	-1.7	-1.6	-1.7	-0.9	-1.4	-2.3	0.2
Prostate Cancer	1.3	1.8	5.0	0.4	0.4	1.2	0.9	1.8	1.1	1.5	1.6	1.8	1.7	1.5	1.4	0.5	0.7	2.2	-1.0
Qualifications: A levels/AS levels or equivalent	1.3	2.9	9.4	-2.5	-2.5	-1.9	-1.0	-1.1	-1.9	-1.0	-1.4	-0.5	-1.4	-1.5	-1.7	-3.1	-1.4	-0.2	-1.7
Medication: Ibuprofen	1.3	1.5	7.6	-1.3	0.1	0.1	0.5	1.6	-0.1	1.4	1.0	1.6	1.1	1.1	0.8	-0.1	-0.1	1.8	-2.8
Knee pain experienced in last month	1.3	2.0	3.4	1.3	1.8	1.5	1.8	1.5	1.7	0.9	1.5	0.7	1.5	1.5	1.6	0.7	1.6	0.9	1.3
Hypertension (Self-reported)	1.3	3.6	8.3	-1.5	-2.9	-2.0	-2.6	-1.9	-2.4	-1.9	-2.1	-1.1	-1.9	-1.9	-2.0	-1.2	-1.9	-0.6	-0.6
Ever depressed for a whole week	1.3	1.6	2.7	1.5	1.1	1.4	1.5	1.0	1.4	1.2	1.3	1.2	1.2	1.2	1.3	1.2	1.6	0.8	0.6
Hair/balding pattern: Pattern 4	1.2	3.0	14.6	2.4	2.2	1.9	0.8	1.5	1.9	1.6	1.1	1.1	1.1	1.2	1.4	3.8	1.6	0.3	0.8
Blood clot in the leg (DVT)	1.2	1.6	4.8	1.0	0.3	1.4	0.6	1.7	1.0	1.2	0.9	1.9	1.0	1.0	0.9	1.5	1.3	2.2	-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.5	9.3	1.9	1.4	1.2	0.8	0.4	1.4	-0.5	0.2	-0.3	0.1	0.2	0.6	1.2	1.4	0.3	3.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.4	2.8	-0.1	1.5	0.8	1.2	1.5	0.9	1.7	1.4	1.2	1.3	1.4	1.3	0.9	0.6	0.7	-1.5
Hearing aid user	1.2	1.4	2.6	-1.6	-0.3	-1.3	-0.6	-0.9	-0.9	-1.3	-1.2	-1.4	-1.3	-1.2	-1.3	-1.6	-1.0	-1.2	0.5
Medication: Bendroflumethiazide	1.2	1.8	6.2	-1.8	-2.4	-1.1	-1.4	-0.3	-1.6	-0.1	-0.9	0.5	-0.8	-0.9	-1.2	-1.3	-1.1	0.6	-2.5
Vascular/heart problems diagnosed by doctor	1.2	3.3	7.0	1.1	2.6	1.8	2.6	1.8	2.2	2.0	2.2	1.2	2.0	2.0	2.1	0.8	1.8	0.6	0.1
Rheumatoid Arthritis	1.1	1.5	2.7	-0.4	-0.6	-1.2	-1.3	-1.5	-1.0	-1.6	-1.6	-1.6	-1.5	-1.3	-1.2	-0.4	-1.0	-1.4	1.1
Blood Platelet Count	1.1	12.9	22.0	1.9	3.4	3.7	3.9	4.4	3.5	4.7	3.9	4.3	3.6	3.6	3.4	3.0	3.8	3.1	-2.2
Frequency of depressed mood in last 2 weeks	1.1	1.5	3.3	1.5	0.9	1.5	0.9	1.4	1.3	0.9	0.7	1.3	0.7	0.7	0.8	1.8	1.7	1.5	0.8
Taking other prescription medications	1.1	1.8	4.0	0.3	-0.9	-1.1	-1.4	-2.0	-1.1	-1.9	-1.1	-2.0	-1.1	-1.0	-0.9	-0.5	-1.3	-1.5	1.7
Multivitamins +/- minerals	1.1	1.4	2.9	0.3	1.1	1.2	1.7	1.2	1.0	1.6	1.4	1.4	1.3	1.2	1.0	0.8	1.5	0.5	-0.9
Supplements: Glucosamine	1.1	1.4	3.9	0.5	0.1	1.1	0.5	1.4	0.7	1.2	1.2	1.8	1.4	1.4	1.2	1.3	0.9	2.0	-0.9
Had menopause	1.1	1.3	3.8	0.2	0.8	-0.5	-0.4	-1.1	-0.2	-1.5	-1.2	-1.9	-1.3	-1.4	-1.1	0.2	-0.3	-1.9	1.9
Medication for cholesterol, blood pressure or diabetes	1.1	1.8	4.5	0.7	1.7	1.2	2.1	1.1	1.6	1.3	1.8	0.7	1.6	1.6	1.5	0.2	1.4	0.4	0.4
Health satisfaction	1.1	1.4	2.3	-1.1	-0.7	-1.3	-1.1	-1.0	-1.2	-0.7	-1.3	-1.2	-1.3	-1.5	-1.4	-0.9	-1.4	-1.5	-0.8
Medication: Omeprazole	1.1	1.3	10.5	0.8	1.2	0.1	0.5	-0.6	0.6	-1.4	-0.7	-1.4	-0.9	-0.7	-0.4	0.0	0.8	-1.1	3.2
Medication: Seretide 50 evohaler	1.1	1.2	2.3	-1.5	-0.9	-1.4	-0.9	-1.3	-1.3	-0.4	-0.7	-0.9	-0.6	-0.7	-0.8	-1.3	-1.5	-1.4	-1.2
Comparative height size at age 10	1.1	5.8	12.6	0.8	2.6	2.4	3.5	3.1	2.6	2.8	2.8	2.5	2.4	2.4	2.2	0.6	2.8	2.2	-0.7
Loneliness, isolation	1.1	1.5	4.0	2.0	0.7	1.4	0.3	0.8	1.2	0.7	1.1	1.0	1.2	1.3	1.4	1.9	1.0	1.2	1.1
Eye problems/disorders: Cataract	1.1	1.2	4.6	-0.5	0.3	-0.7	0.1	-0.9	-0.3	-0.9	-1.1	-1.7	-1.3	-1.4	-1.3	-1.1	-0.1	-2.1	1.3
Age started oral contraceptive pill	1.1	1.4	3.0	-0.9	-1.6	-1.2	-1.7	-1.2	-1.4	-1.2	-1.3	-0.8	-1.1	-1.1	-1.2	-0.7	-1.4	-0.4	-0.4
Schizophrenia vs Biploar Disorder	1.0	1.4	3.8	1.6	1.7	1.4	1.0	0.9	1.4	0.9	1.0	0.7	1.0	0.9	1.1	1.9	1.2	0.4	0.8
Worry (Nagel 2018)	1.0	2.0	4.4	-1.3	-2.1	-1.6	-1.7	-1.4	-1.8	-1.2	-1.4	-0.9	-1.3	-1.3	-1.3	-1.7	-1.7	-0.5	-0.9
Systolic blood pressure, automated reading	1.0	2.8	6.4	0.0	-0.7	-1.0	-1.4	-1.8	-0.9	-2.5	-2.0	-2.2	-2.1	-2.1	-1.9	-0.3	-0.9	-1.6	2.4
Townsend deprivation index at recruitment	1.0	1.4	3.6	1.3	1.9	1.3	0.9	1.2	1.4	0.9	1.1	0.6	1.0	1.0	1.1	1.8	0.9	0.6	0.5
Age when periods started (menarche)	1.0	2.3	4.1	-0.9	-0.9	-1.5	-1.7	-1.4	-1.4	-2.0	-1.8	-1.9	-1.8	-1.8	-1.6	-1.3	-1.6	-1.2	0.8
Mouth/teeth dental problems	1.0	1.6	3.2	1.4	0.9	1.5	1.4	1.2	1.4	0.9	1.2	1.2	1.2	1.2	1.1	1.4	1.8	1.2	1.0
Headache pain in last month	1.0	1.7	8.9	-2.2	-1.6	-1.3	-0.8	-0.7	-1.6	0.3	-0.7	0.2	-0.7	-0.7	-1.2	-0.9	-1.2	-0.6	-3.0
Eye problems/disorders: None of the above	1.0	1.2	6.6	0.7	-1.0	0.6	-0.6	0.9	0.1	0.6	0.8	1.7	1.1	1.3	1.1	1.0	0.0	2.6	-0.7
Alcohol intake frequency.	1.0	2.2	4.4	-1.6	-2.0	-1.7	-1.7	-1.7	-2.0	-0.6	-1.1	-0.7	-1.0	-1.1	-1.3	-0.7	-1.9	-1.4	-2.1
Whole body water mass	1.0	5.6	11.6	-0.2	2.6	2.0	2.8	3.4	2.1	2.9	2.6	2.7	2.4	2.5	2.2	1.1	2.3	2.4	-1.9
Number of self-reported non-cancer illnesses	1.0	1.8	3.4	-0.9	-1.4	-1.4	-1.4	-1.7	-1.5	-1.9	-1.3	-1.6	-1.2	-1.2	-1.2	-1.2	-1.4	-1.0	0.6
Basal metabolic rate	1.0	5.4	11.2	-0.6	2.3	1.8	2.7	3.3	1.9	2.9	2.5	2.8	2.4	2.5	2.0	0.7	2.0	2.5	-2.4
Crohns Disease (2012)	0.9	1.4	3.6	0.0	1.1	1.0	1.1	1.6	0.9	1.9	1.1	1.5	1.1	1.0	0.8	1.0	0.8	0.8	-1.7
Type 2 Diabetes (T2D) (2012)	0.9	1.0	8.8	-1.1	0.4	-0.0	0.2	1.2	-0.1	1.4	0.5	0.9	0.5	0.4	0.3	-0.3	-0.7	0.6	-3.0
Relative age voice broke	0.9	1.4	4.6	1.2	-0.1	1.1	0.6	1.0	1.0	0.7	1.4	1.3	1.6	1.5	1.5	0.5	0.9	2.1	0.5
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	2.8	-0.2	-1.7	-1.1	-1.6	-1.6	-1.3	-1.0	-0.8	-0.8	-0.5	-0.6	-0.6	-0.4	-1.3	-0.6	-0.2
Forced vital capacity (FVC)	0.9	3.4	6.9	-0.4	-1.1	-1.7	-2.1	-2.1	-1.4	-2.5	-2.0	-2.6	-2.0	-1.9	-1.7	-0.6	-1.8	-1.9	1.9
Medication: Paracetamol	0.9	1.5	4.4	-2.1	-1.5	-1.5	-0.9	-0.8	-1.5	-0.3	-0.6	-0.4	-0.6	-0.6	-0.9	-1.6	-1.5	-0.5	-1.9
Exposure to tobacco smoke outside home	0.9	1.2	2.4	0.5	0.7	1.1	1.2	1.2	0.9	1.4	1.3	1.5	1.2	1.2	1.0	1.0	1.2	1.1	-0.8
Emphysema/chronic bronchitis	0.9	1.0	1.8	-0.4	-0.8	-1.1	-1.3	-1.2	-1.0	-1.4	-1.1	-1.3	-0.9	-0.9	-0.9	-0.5	-1.2	-1.0	0.7
Suffer from ‘nerves’	0.9	1.4	2.6	-0.5	-1.0	-1.1	-1.6	-0.9	-1.1	-1.5	-1.6	-1.2	-1.5	-1.4	-1.4	-0.7	-1.3	-0.4	0.6
Age at last live birth	0.9	1.3	8.4	-0.8	-0.2	0.3	0.3	1.2	-0.0	1.6	0.6	1.8	0.7	0.7	0.5	0.1	0.2	1.4	-2.9
Whole body fat-free mass	0.9	5.4	11.0	-0.3	2.5	2.0	2.8	3.3	2.1	2.8	2.6	2.7	2.4	2.5	2.1	1.0	2.2	2.4	-1.9
Mouth/teeth dental problems: Mouth ulcers	0.9	1.5	3.3	-0.5	-1.4	-1.3	-1.8	-1.5	-1.4	-1.4	-1.1	-1.4	-0.9	-0.9	-0.8	-1.1	-1.8	-0.8	-0.0
Average weekly champagne plus white wine intake	0.9	1.2	5.0	-0.7	-0.6	0.1	0.0	0.7	-0.3	1.2	1.0	1.6	1.3	1.5	1.2	-0.2	-0.2	1.5	-2.2
Financial situation satisfaction	0.9	1.2	3.3	0.2	0.3	0.8	0.6	0.8	0.6	1.7	1.2	1.6	1.4	1.2	1.2	0.9	0.4	0.8	-1.8
Ever had prostate specific antigen (PSA) test	0.9	1.0	2.5	-0.7	0.2	0.5	1.0	1.2	0.4	1.2	1.2	1.4	1.2	1.2	0.9	-0.4	0.6	1.3	-1.6
Supplements: Calcium	0.9	1.0	2.1	1.4	0.7	1.2	1.0	0.5	1.1	0.5	1.1	0.6	1.1	1.1	1.1	1.2	1.3	0.7	1.2
Mean Putamen Volume	0.8	1.0	2.4	0.7	1.5	1.0	1.2	0.9	1.2	1.0	1.0	0.6	1.0	1.0	1.1	1.0	1.1	0.2	0.3
HDL Cholesterol	0.8	1.3	2.6	-0.3	-1.1	-1.1	-1.6	-1.3	-1.1	-1.5	-1.3	-1.2	-1.2	-1.0	-1.0	-0.5	-1.2	-0.7	1.0
Trunk fat mass	0.8	3.4	14.9	-1.7	0.4	0.6	1.7	2.1	0.4	2.5	1.8	2.5	1.8	1.7	1.2	-0.5	0.8	1.9	-3.9
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	3.2	-0.7	-1.3	-0.9	-1.0	-0.6	-1.0	-1.0	-1.7	-0.6	-1.8	-1.7	-1.7	-0.8	-0.6	-0.4	0.1
Alcohol intake versus 10 years previously	0.8	1.2	3.0	-0.5	-1.3	-1.1	-1.7	-1.4	-1.4	-1.0	-1.1	-1.0	-0.9	-0.9	-0.9	-0.1	-1.6	-1.1	-0.4
Asthma	0.8	1.6	3.9	-1.6	-2.0	-1.6	-1.5	-1.6	-1.8	-1.0	-0.9	-0.6	-0.7	-0.5	-0.8	-1.3	-1.5	-0.7	-1.1
Standing height	0.8	7.5	13.0	0.5	2.4	2.4	3.5	3.6	2.7	2.9	3.3	3.0	3.1	3.2	2.9	0.4	2.7	3.3	-0.9
Mouth/teeth dental problems: Bleeding gums	0.8	1.1	3.4	-1.1	0.4	-1.0	-0.2	-0.8	-0.6	-0.8	-1.1	-1.5	-1.3	-1.4	-1.2	-1.1	-0.8	-1.8	0.0
Mean time to correctly identify matches	0.8	1.6	3.3	1.6	1.3	1.6	0.8	1.2	1.7	0.8	1.0	1.0	1.1	1.0	1.2	1.8	1.3	1.0	1.1
Deep venous thrombosis (DVT) (self-reported)	0.8	1.1	3.7	1.0	0.1	1.2	0.4	1.4	0.8	1.0	0.6	1.7	0.7	0.7	0.7	1.3	1.1	1.9	-0.2
Blood Red Count	0.7	6.7	10.7	-2.6	-2.6	-3.0	-3.0	-2.7	-3.2	-1.6	-2.6	-1.9	-2.5	-2.4	-2.6	-1.6	-3.3	-2.7	-2.3
Height	0.7	13.4	22.7	2.5	4.4	3.9	4.8	4.7	4.5	2.9	3.9	2.8	3.5	3.6	3.6	1.7	4.2	3.8	1.9
Tanning	0.7	8.5	10.7	2.9	2.4	3.3	2.5	3.1	3.0	2.7	3.0	3.2	3.1	3.2	3.3	3.2	3.2	3.2	0.6
Vitamin and mineral supplements	0.7	1.0	2.5	-0.1	-0.4	-0.8	-0.9	-1.0	-0.5	-1.5	-1.2	-1.4	-1.1	-1.1	-0.9	-0.8	-0.7	-0.8	1.6
Trunk fat percentage	0.7	2.7	16.7	-2.0	-0.3	0.1	1.2	1.5	-0.1	2.2	1.3	2.2	1.3	1.2	0.7	-1.0	0.3	1.5	-4.1
Maternal smoking around birth	0.7	0.9	2.7	1.3	1.0	1.1	0.5	0.9	1.1	0.3	0.6	0.7	0.6	0.7	0.7	1.6	1.1	1.0	1.4
Heart attack	0.7	0.9	2.3	1.5	1.2	1.2	0.7	0.8	1.2	0.3	0.6	0.4	0.6	0.5	0.8	1.4	1.1	0.6	1.4
Weight	0.7	3.6	9.6	-1.5	1.5	1.0	2.1	2.6	1.0	2.5	2.0	2.4	1.8	1.9	1.4	0.1	1.3	2.0	-3.1
Trunk fat-free mass	0.7	4.1	8.5	-0.1	2.5	1.8	2.4	2.9	1.9	2.3	2.3	2.1	2.1	2.3	2.0	1.0	1.9	2.1	-1.3
Trunk predicted mass	0.7	4.3	8.6	0.0	2.5	1.8	2.4	2.9	2.0	2.3	2.3	2.2	2.2	2.3	2.0	1.1	1.9	2.1	-1.2
Birth weight of first child	0.7	1.2	3.3	-0.0	-0.0	0.7	0.4	1.2	0.5	1.3	1.1	1.8	1.3	1.3	1.1	1.0	0.6	1.8	-1.5
Angina (self-reported)	0.7	0.9	2.7	0.6	-1.0	-0.6	-1.4	-1.2	-0.7	-1.6	-0.8	-1.0	-0.7	-0.6	-0.5	0.6	-0.7	0.0	1.6
Friendships satisfaction	0.7	0.8	2.5	-0.3	0.9	0.7	1.6	0.8	0.8	1.1	1.2	0.9	1.1	1.0	1.0	-0.7	0.9	0.5	-0.7
Eye problems/disorders: Glaucoma	0.7	0.9	2.7	-0.2	-0.2	-0.7	-0.5	-1.3	-0.7	-1.1	-1.0	-1.3	-1.1	-1.1	-1.0	-0.3	-0.5	-1.6	0.8
Medication: Omeprazole (e.g. Zanprol)	0.7	0.8	6.0	0.5	0.9	-0.0	0.5	-0.5	0.4	-1.1	-0.7	-1.1	-0.9	-0.7	-0.5	-0.4	0.6	-0.9	2.5
Heart attack/myocardial infarction (self-reported)	0.7	0.9	2.7	1.6	1.2	1.1	0.6	0.6	1.1	0.1	0.4	0.2	0.5	0.4	0.7	1.4	1.0	0.4	1.6
Bipolar Disorder (2011)	0.6	0.5	1.3	0.3	1.1	0.7	1.0	0.9	0.8	0.5	0.9	0.4	0.9	0.8	0.9	0.0	0.5	0.9	0.0
Waist Hip Ratio (WHR)	0.6	2.8	6.8	-2.0	-2.6	-1.9	-1.7	-1.7	-2.2	-1.1	-1.5	-0.7	-1.3	-1.4	-1.5	-2.2	-1.8	-0.7	-1.5
Average weekly spirits intake	0.6	0.8	2.3	-0.1	0.0	-0.4	-0.4	-0.8	-0.2	-1.3	-1.0	-1.4	-1.0	-1.2	-1.0	-0.5	-0.3	-0.9	1.5
Angina	0.6	0.8	2.5	0.6	-1.0	-0.5	-1.3	-1.1	-0.6	-1.5	-0.7	-0.9	-0.6	-0.5	-0.5	0.5	-0.7	-0.0	1.6
Fed-up feelings	0.6	1.0	2.7	1.4	1.2	1.1	0.7	0.9	1.1	0.7	0.8	0.6	0.8	0.9	1.0	1.6	1.0	0.6	1.0
Serious illness, injury or assault to yourself	0.6	0.8	2.1	0.0	-0.9	-0.7	-0.4	-1.3	-0.6	-1.2	-0.7	-1.1	-0.8	-0.8	-0.7	-1.0	-0.3	-1.0	1.5
Hearing difficulty/problems with background noise	0.6	1.0	2.1	-0.6	-0.9	-1.1	-1.2	-1.2	-1.1	-1.5	-1.2	-1.1	-1.1	-0.9	-0.8	-0.8	-1.0	-0.7	0.7
Had other major operations	0.6	0.7	2.1	-0.4	-0.4	-0.9	-0.8	-1.1	-0.9	-1.5	-0.8	-1.3	-0.7	-0.5	-0.5	-0.4	-0.9	-0.8	1.1
Diabetes (self-reported)	0.6	0.9	2.8	-0.9	-1.5	-0.9	-1.2	-0.6	-1.2	-0.1	-0.8	-0.1	-0.6	-0.7	-0.8	-0.8	-1.2	-0.2	-1.7
Hip circumference	0.6	2.6	11.0	-1.9	0.7	0.4	1.4	2.0	0.4	2.0	1.6	2.1	1.5	1.6	1.1	-0.4	0.5	1.8	-3.3
Pulse rate	0.6	0.9	2.2	-0.9	-1.0	-0.9	-1.1	-0.7	-1.1	-0.2	-1.1	-0.3	-1.1	-1.2	-1.3	-0.1	-1.0	-0.8	-1.5
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	2.8	-1.2	-1.7	-0.6	-0.5	0.2	-0.9	-0.4	-0.3	0.5	-0.2	-0.1	-0.4	-1.5	-0.4	1.4	-0.8
Arm fat mass (right)	0.6	2.3	11.4	-1.7	0.9	0.5	1.6	1.9	0.4	2.2	1.4	1.9	1.3	1.2	0.8	-0.3	0.7	1.1	-3.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	1.0	2.8	0.8	0.6	1.1	1.0	1.5	1.0	0.9	0.8	1.2	0.7	0.8	0.8	0.3	1.2	1.7	-0.0
Whole body fat mass	0.6	2.4	14.7	-2.0	-0.0	0.1	1.1	1.6	-0.1	2.0	1.3	2.0	1.2	1.1	0.6	-0.8	0.3	1.3	-3.8
Leg pain on walking	0.6	0.8	2.1	-1.2	-1.1	-1.0	-0.9	-0.5	-1.1	-0.6	-0.6	-0.4	-0.5	-0.5	-0.6	-1.4	-1.2	0.0	-1.0
Asthma (self-reported)	0.6	1.1	2.9	-1.4	-1.7	-1.3	-1.3	-1.4	-1.5	-0.8	-0.7	-0.4	-0.5	-0.3	-0.5	-1.1	-1.2	-0.6	-0.9
Medication: Aspirin	0.6	0.8	1.7	-0.6	-0.6	-0.9	-0.7	-0.7	-0.8	-0.4	-0.9	-1.0	-1.1	-1.2	-1.2	-0.6	-0.9	-1.3	-0.4
Arm fat mass (left)	0.6	2.6	13.1	-1.9	0.7	0.4	1.6	2.0	0.3	2.2	1.5	2.1	1.3	1.3	0.8	-0.5	0.7	1.4	-3.6
Medication: Paracetamol	0.6	1.0	5.6	-1.8	-1.2	-1.1	-0.6	-0.4	-1.2	0.2	-0.3	0.3	-0.2	-0.3	-0.6	-0.8	-1.1	-0.2	-2.4
Alzheimer’s Disease (in father)	0.5	0.6	1.9	1.4	-0.4	0.8	0.1	0.5	0.6	0.6	0.7	0.8	0.8	0.7	0.7	0.8	0.5	1.2	0.4
Schizophrenia (2014)	0.5	1.1	4.1	1.4	2.0	0.8	0.9	0.2	1.2	-0.2	-0.0	-0.7	-0.2	-0.3	0.0	1.4	0.8	-0.9	2.0
Smoking Status	0.5	1.2	4.3	1.6	1.6	1.1	0.9	0.5	1.3	0.2	0.7	0.1	0.7	0.8	1.1	1.0	1.2	0.2	2.1
Hypothyroidism (self reported)	0.5	1.1	9.5	1.4	1.2	0.6	0.6	0.0	1.0	-0.8	0.3	-0.9	0.2	0.3	0.5	0.2	0.7	-0.1	3.1
Respiratory disease	0.5	1.2	4.2	-1.4	-2.0	-1.1	-1.2	-0.9	-1.5	0.1	-0.2	0.4	0.1	0.2	-0.1	-1.2	-1.3	-0.0	-2.0
Waist circumference	0.5	1.8	13.3	-2.6	-0.5	-0.5	0.4	1.1	-0.7	1.2	0.5	1.4	0.4	0.4	-0.1	-1.2	-0.3	1.1	-3.6
Hair/balding pattern: Pattern 2	0.5	0.7	3.4	-1.7	-0.5	-0.8	0.2	0.1	-0.8	0.1	-0.0	0.2	-0.1	-0.2	-0.3	-1.5	-0.6	0.3	-1.8
Allergy	0.5	1.3	4.3	2.1	1.1	1.3	0.5	0.6	1.2	0.1	0.6	0.1	0.5	0.4	0.5	2.1	1.1	0.5	2.1
Pain all over the body in last month	0.5	0.5	1.4	0.2	-0.4	-0.5	-0.8	-0.7	-0.5	-1.1	-0.7	-1.1	-0.7	-0.7	-0.5	-0.5	-0.7	-0.5	1.2
Arm fat percentage (right)	0.5	2.1	12.8	-1.6	0.4	0.3	1.2	1.6	0.2	2.1	1.3	1.8	1.1	1.1	0.6	-0.4	0.3	1.1	-3.6
Glaucoma (self-reported)	0.5	0.6	3.6	0.8	1.0	0.2	0.5	-0.5	0.4	-0.7	-0.3	-1.0	-0.4	-0.5	-0.2	0.5	0.6	-1.1	1.9
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	7.5	1.3	1.3	0.6	0.6	0.0	1.0	-0.7	0.2	-1.1	0.1	0.0	0.3	0.0	0.5	-0.5	2.7
Medication: Ventolin 100micrograms inhaler	0.5	0.6	2.7	-1.5	-0.5	-1.0	-0.5	-0.5	-0.9	0.0	-0.1	-0.2	-0.1	-0.0	-0.2	-0.9	-1.0	-0.5	-1.6
Forced vital capacity (FVC), Best measure	0.5	1.8	4.1	-0.3	-0.4	-1.2	-1.4	-1.2	-0.9	-1.9	-1.6	-2.0	-1.5	-1.4	-1.4	-0.4	-1.2	-1.3	1.7
Body fat percentage	0.5	2.0	15.3	-2.3	-0.7	-0.4	0.6	0.9	-0.7	1.6	0.7	1.6	0.7	0.6	0.1	-1.3	-0.3	0.9	-3.9
Leg fat percentage (right)	0.5	2.0	8.0	-2.5	-1.6	-1.5	-0.9	-0.7	-1.8	-0.1	-0.6	0.0	-0.5	-0.6	-1.0	-1.7	-1.5	-0.4	-2.8
Arm fat-free mass (right)	0.5	2.8	5.7	-0.7	1.6	1.2	2.1	2.4	1.3	2.0	1.9	2.0	1.7	1.8	1.4	0.4	1.6	1.7	-1.7
Medication: Blood pressure	0.5	0.9	3.2	-0.5	-1.8	-0.8	-1.6	-0.8	-1.3	-0.9	-1.1	-0.1	-0.8	-0.8	-0.9	-0.1	-0.9	0.2	-0.5
Number of full sisters	0.5	0.6	1.5	0.5	0.5	0.9	0.8	0.9	0.9	0.5	1.1	0.7	1.1	0.9	0.9	0.2	0.6	1.2	0.3
Overall health rating	0.5	1.1	1.8	-0.8	-0.8	-1.3	-1.1	-1.2	-1.2	-1.0	-1.0	-1.3	-1.0	-1.0	-1.1	-0.8	-1.3	-1.2	-0.1
Arm fat percentage (left)	0.5	2.2	13.8	-1.8	0.2	0.2	1.2	1.6	0.1	2.1	1.2	1.9	1.1	1.0	0.6	-0.6	0.3	1.1	-3.7
Smoking status: Current	0.5	0.7	4.9	1.5	1.1	0.7	0.1	0.2	0.8	-0.5	0.0	-0.4	0.1	0.1	0.4	1.1	0.5	0.0	2.2
Arm fat-free mass (left)	0.5	2.4	5.0	-0.8	1.8	1.1	1.8	2.2	1.1	1.9	1.6	1.8	1.5	1.6	1.3	0.5	1.3	1.4	-1.9
Basal cell carcinoma (self-reported)	0.5	0.6	2.0	-1.2	-1.2	-0.8	-0.2	-0.5	-1.0	0.0	-0.3	0.1	-0.4	-0.3	-0.6	-1.2	-0.4	-0.3	-1.4
Arm predicted mass (left)	0.5	2.8	5.6	-0.8	1.7	1.2	1.9	2.4	1.2	2.1	1.8	2.0	1.7	1.8	1.4	0.5	1.4	1.7	-2.1
Depressed Affect (Nagel 2018)	0.4	0.9	2.5	1.5	1.2	1.0	1.0	0.4	1.1	0.4	0.7	0.1	0.7	0.8	0.9	1.0	1.2	-0.1	1.6
Intelligence (Savage-Jansen 2018)	0.4	1.2	2.8	-1.6	-0.9	-1.2	-0.7	-1.0	-1.2	-0.8	-1.0	-0.9	-0.9	-1.1	-1.1	-1.7	-1.1	-1.0	-0.8
Schizophrenia (2018)	0.4	0.8	5.4	0.8	1.2	0.2	0.4	-0.4	0.6	-0.8	-0.5	-1.1	-0.7	-0.5	-0.3	0.5	0.5	-1.1	2.3
Reaction Time	0.4	0.8	2.6	1.4	0.9	1.1	0.3	0.7	1.2	0.4	0.6	0.6	0.6	0.6	0.7	1.6	0.8	0.7	1.2
Breast Cancer	0.4	1.1	3.8	0.3	1.0	-0.3	-0.6	-0.4	-0.1	-1.3	-1.2	-1.5	-1.4	-1.2	-0.9	0.6	-0.2	-1.1	2.0
Age at First Birth	0.4	0.6	4.6	-1.3	-0.3	-0.3	0.4	0.5	-0.3	0.9	0.1	0.6	0.1	0.0	-0.1	-1.2	-0.2	0.2	-2.1
Primary Biliary Cirrhosis	0.4	0.6	4.6	-1.1	0.3	-0.2	0.8	0.2	-0.2	1.0	0.4	0.4	0.2	0.0	-0.1	-0.8	-0.1	-0.4	-2.1
Chronotype (morning person)	0.4	0.9	3.1	1.3	-0.5	0.9	-0.4	0.7	0.2	0.5	0.6	1.3	0.9	0.8	0.9	1.6	0.4	1.8	-0.2
Ever used hormone-replacement therapy (HRT)	0.4	0.5	2.3	0.1	0.4	-0.4	-0.2	-0.7	-0.3	-1.2	-0.8	-1.1	-0.8	-0.6	-0.4	-0.2	-0.1	-0.7	1.5
Medication for hormone replacement therapy	0.4	0.4	1.5	-0.2	-0.4	-0.5	-0.8	-0.4	-0.5	-1.2	-0.8	-0.7	-0.8	-0.6	-0.5	-0.3	-0.5	0.1	1.0
Medication: Co-codamol	0.4	0.4	1.1	-0.0	-0.5	-0.6	-1.0	-0.7	-0.7	-1.0	-0.7	-0.7	-0.6	-0.5	-0.6	0.0	-0.8	-0.2	0.7
Diabetes (father)	0.4	0.4	1.2	-1.1	-0.1	-0.9	-0.3	-0.5	-0.8	-0.2	-0.5	-0.6	-0.5	-0.5	-0.5	-0.8	-0.8	-0.8	-0.9
Hand grip strength (right)	0.4	1.0	3.6	0.6	1.4	0.9	1.4	0.8	1.3	0.1	0.7	0.1	0.5	0.8	0.8	-0.1	1.5	0.4	1.9
Current tobacco smoking	0.4	0.7	4.9	1.1	0.6	0.1	-0.6	-0.5	0.2	-1.1	-0.7	-1.1	-0.6	-0.6	-0.3	0.7	-0.1	-0.6	2.2
Medication: Atenolol	0.4	0.5	2.6	-0.6	-1.6	-0.3	-0.9	-0.1	-0.9	-0.0	-0.1	0.7	0.1	-0.0	-0.2	-0.3	-0.7	1.1	-1.3
Medication: Levothyroxine sodium	0.4	0.7	6.1	1.2	1.2	0.4	0.3	-0.0	0.7	-0.8	0.1	-1.1	0.0	0.0	0.3	0.1	0.1	-0.4	2.5
Qualifications: None of the above	0.4	0.8	2.0	-0.5	-0.1	-0.9	-0.9	-0.8	-0.6	-1.3	-1.0	-1.4	-1.0	-1.0	-1.0	-0.3	-1.1	-1.0	0.9
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	3.2	-0.3	-1.8	-0.3	-0.6	-0.4	-0.7	0.5	0.3	0.6	0.5	0.2	0.1	-0.8	-0.6	0.5	-1.6
Gout (self-reported)	0.4	0.5	1.5	-0.1	0.7	-0.1	0.1	-0.4	-0.0	-0.7	-0.8	-0.9	-1.1	-1.1	-1.0	0.4	0.1	-1.2	0.7
Worry too long after embarrassment	0.4	0.6	3.7	-1.6	-0.7	-0.7	-0.3	0.1	-0.8	0.2	-0.1	0.4	-0.1	0.0	-0.2	-1.1	-0.7	0.5	-1.9
Number of children fathered	0.4	0.4	1.6	-0.7	1.0	0.4	1.3	0.8	0.5	0.7	0.7	0.5	0.5	0.6	0.4	-0.5	0.7	0.2	-0.5
Age at first live birth	0.4	0.6	4.7	-0.8	-0.8	-0.2	-0.2	0.5	-0.3	0.9	0.3	0.9	0.4	0.3	0.1	-0.5	-0.5	1.0	-2.2
Arm predicted mass (right)	0.4	1.9	4.5	-1.0	1.6	0.9	1.8	2.1	1.0	1.6	1.4	1.6	1.2	1.4	1.0	0.1	1.2	1.3	-1.6
Pulse rate, automated reading	0.4	1.3	2.4	-0.1	-0.8	-1.0	-1.6	-1.3	-1.0	-0.9	-1.4	-1.1	-1.4	-1.4	-1.3	0.4	-1.3	-1.4	-0.1
Had major operations	0.4	0.5	2.3	1.0	0.2	0.7	0.5	0.5	0.7	-0.3	0.5	0.3	0.5	0.6	0.6	0.2	0.7	1.1	1.5
Family relationship satisfaction	0.4	0.5	1.8	1.2	1.0	0.8	0.5	0.3	0.9	0.2	0.1	0.1	0.2	0.2	0.5	0.8	0.9	-0.0	1.3
Illnesses of father: Heart disease	0.4	0.6	1.6	-1.1	-0.9	-0.8	-0.7	-0.5	-0.9	-0.3	-0.6	-0.2	-0.5	-0.6	-0.7	-0.8	-0.9	-0.3	-1.3
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	2.8	-0.2	1.4	0.7	1.7	1.2	1.1	0.8	1.0	0.4	0.7	0.8	0.7	-0.7	1.0	0.4	0.1
Long-standing illness, disability or infirmity	0.4	0.6	1.0	-0.6	-0.6	-0.9	-0.6	-0.9	-0.9	-1.0	-0.8	-1.0	-0.8	-0.8	-0.8	-0.9	-0.8	-0.8	0.3
Ever taken oral contraceptive pill	0.4	0.5	1.7	1.2	-0.7	0.4	-0.9	-0.0	0.0	-0.6	-0.1	0.2	0.1	0.2	0.3	1.0	0.1	1.1	1.3
Mother’s age at death	0.4	0.5	2.4	0.9	0.4	0.7	-0.2	0.7	0.5	1.0	0.5	0.8	0.6	0.6	0.6	1.6	0.2	0.5	-0.7
Leg fat percentage (left)	0.4	1.5	7.6	-2.3	-1.3	-1.3	-0.7	-0.5	-1.5	0.1	-0.4	0.2	-0.3	-0.4	-0.7	-1.5	-1.3	-0.2	-2.8
Fractured/broken bones in last 5 years	0.4	0.5	1.6	0.6	-0.8	-0.2	-0.8	-0.8	-0.2	-0.9	-0.8	-0.5	-0.8	-0.7	-0.5	0.2	-0.1	-0.3	1.2
Crohns Disease (2017)	0.3	0.6	2.0	-0.3	0.6	0.6	0.8	1.1	0.5	1.3	0.4	1.1	0.3	0.2	0.1	0.6	0.8	0.4	-1.4
Major Depression (MDD)	0.3	0.4	1.4	1.0	-0.2	0.6	-0.4	0.2	0.2	0.5	0.5	0.7	0.8	0.7	0.8	1.2	-0.0	0.8	-0.3
Neuroticism (2016)	0.3	0.4	1.2	-0.3	-1.1	-0.6	-0.9	-0.7	-0.9	-0.5	-0.8	-0.2	-0.7	-0.8	-0.8	-0.0	-0.6	-0.3	-0.5
Blood White Count	0.3	2.1	7.0	1.4	2.0	1.6	0.9	1.8	1.5	1.7	1.1	1.3	1.1	1.1	1.2	2.6	1.1	0.7	-0.6
Type 2 Diabetes (T2D) (2018)	0.3	0.5	1.6	-0.7	-1.3	-0.6	-0.7	-0.3	-0.8	0.0	-0.6	0.1	-0.6	-0.5	-0.6	-1.2	-0.5	-0.1	-1.0
Hearing difficulty/problems: Yes	0.3	0.5	2.3	-1.5	0.3	-0.9	-0.2	-0.1	-0.6	-0.2	-0.4	-0.6	-0.4	-0.3	-0.4	-1.0	-0.9	-0.8	-0.8
Ever had hysterectomy (womb removed)	0.3	0.3	2.4	-0.1	0.4	-0.3	-0.1	-0.3	0.0	-0.9	-0.6	-0.7	-0.6	-0.3	-0.3	-0.1	0.2	-0.4	1.5
Supplements: Zinc	0.3	0.4	1.5	-0.4	0.5	0.4	1.2	0.7	0.5	0.4	0.6	0.5	0.4	0.4	0.3	-0.9	0.9	0.7	-0.1
Medication: Metformin	0.3	0.4	0.7	0.5	0.3	0.5	0.3	0.6	0.5	0.8	0.6	0.8	0.7	0.8	0.8	0.5	0.4	0.6	-0.4
Hayfever, allergic rhinitis or eczema	0.3	0.6	4.4	-1.6	0.3	-0.7	0.7	-0.2	-0.3	0.2	-0.0	-0.3	-0.1	-0.0	-0.1	-2.1	-0.3	-0.6	-1.2
Stomach or abdominal pain in last month	0.3	0.3	1.4	-0.3	0.7	-0.3	0.3	-0.1	0.1	-0.7	-0.4	-0.9	-0.7	-0.5	-0.4	-0.8	0.1	-0.6	1.2
Sitting height	0.3	1.8	4.3	0.2	2.1	1.2	2.1	1.9	1.5	1.2	1.3	1.0	1.0	1.2	1.1	0.6	1.7	1.0	0.2
Number of incorrect matches in round	0.3	0.5	1.3	0.4	-0.0	-0.3	-0.5	-1.0	-0.3	-0.9	-0.6	-1.1	-0.6	-0.6	-0.5	0.3	-0.4	-1.1	1.1
Worrier / anxious feelings	0.3	0.6	1.2	-0.7	-1.1	-0.9	-1.0	-0.8	-1.1	-0.7	-0.9	-0.5	-0.8	-0.8	-0.8	-0.5	-0.9	-0.3	-0.5
Medication: Cholesterol lowering	0.3	0.4	1.0	-0.3	-0.8	-0.5	-1.0	-0.4	-0.8	-0.3	-0.9	-0.1	-0.7	-0.8	-0.7	0.0	-0.7	-0.2	-0.8
Depression (self-reported)	0.3	0.3	1.4	0.6	0.2	0.6	0.1	0.9	0.5	0.1	0.1	0.6	0.2	0.2	0.3	0.6	0.7	1.2	0.5
Peak expiratory flow (PEF)	0.3	0.8	3.7	0.9	1.3	1.0	0.5	1.1	0.9	0.6	0.4	0.6	0.3	0.5	0.5	1.9	1.1	0.5	0.5
Loud music exposure frequency	0.3	0.3	1.1	0.4	1.0	0.1	-0.0	-0.1	0.4	-0.1	-0.3	-0.7	-0.4	-0.5	-0.3	0.9	-0.1	-1.1	0.5
Wheeze or whistling in the chest in last year	0.3	0.6	1.9	-1.1	-1.2	-0.9	-0.7	-0.7	-0.9	-0.2	-0.2	-0.2	0.0	-0.0	-0.2	-1.4	-1.0	-0.1	-1.0
Leg fat mass (right)	0.3	1.2	9.2	-2.2	-0.5	-0.5	0.3	0.7	-0.7	1.0	0.4	1.0	0.3	0.3	-0.1	-1.0	-0.4	0.6	-3.0
Medication: Lisinopril	0.3	0.3	0.9	0.0	-0.8	-0.4	-0.9	-0.8	-0.7	0.0	-0.4	0.0	-0.4	-0.3	-0.4	0.8	-0.5	-0.5	-0.9
Illnesses of father: High blood pressure	0.3	0.4	1.3	0.0	0.4	-0.4	-0.8	-0.7	-0.3	-0.7	-0.7	-1.0	-0.7	-0.6	-0.5	0.5	-0.7	-1.1	0.4
Alcohol drinker status: Never	0.3	0.4	1.0	0.1	0.1	0.6	0.3	0.8	0.4	0.7	0.5	1.0	0.6	0.6	0.5	0.5	0.5	1.0	-0.6
Irritability	0.3	0.5	1.3	0.8	0.6	0.6	0.4	0.4	0.5	1.0	0.9	0.5	1.1	1.1	1.2	0.7	0.2	0.3	-0.4
Alcohol drinker status: Previous	0.3	0.3	0.8	-0.3	-0.7	-0.6	-0.7	-0.8	-0.8	-0.0	-0.2	-0.2	-0.2	-0.1	-0.2	0.2	-0.9	-0.6	-0.9
Impedance of whole body	0.3	1.3	6.1	-0.4	-2.5	-1.2	-1.2	-1.6	-1.4	-0.8	-0.7	-0.6	-0.5	-0.6	-0.6	-1.8	-1.3	-0.3	-0.4
Leg fat mass (left)	0.3	1.2	9.2	-2.2	-0.5	-0.6	0.1	0.6	-0.8	0.8	0.2	0.9	0.2	0.2	-0.2	-1.1	-0.5	0.5	-3.0
Bipolar Disorder or Schizophrenia	0.2	0.5	3.4	0.6	1.1	0.2	0.6	-0.1	0.6	-0.7	-0.0	-0.8	-0.2	-0.1	0.1	0.2	0.4	-0.5	1.8
Alzheimer’s Disease (in mother)	0.2	0.2	0.5	-0.6	-0.7	-0.5	-0.5	-0.5	-0.6	-0.3	-0.4	-0.0	-0.4	-0.4	-0.5	-0.2	-0.5	-0.3	-0.6
Verbal and Numeric Reasoning (VNR)	0.2	0.6	1.2	-0.9	-0.3	-0.9	-0.4	-0.9	-0.8	-0.5	-0.7	-0.9	-0.7	-0.8	-0.8	-0.8	-0.9	-1.1	-0.4
Lupus	0.2	0.2	1.3	-0.4	-0.6	-0.1	0.2	0.1	-0.3	0.4	0.4	0.6	0.4	0.4	0.3	-0.6	-0.1	0.6	-1.1
BMI	0.2	1.3	9.1	-2.6	-0.4	-0.7	0.1	0.7	-0.9	0.7	-0.2	0.9	-0.2	-0.1	-0.6	-0.9	-0.3	0.4	-3.0
Sensitivity / hurt feelings	0.2	0.3	1.0	0.4	1.0	0.4	0.9	0.3	0.6	0.3	0.7	-0.0	0.6	0.6	0.6	0.3	0.6	-0.2	0.5
Relative age of first facial hair	0.2	0.4	4.5	0.7	0.1	0.0	-0.1	-0.1	0.4	-0.9	-0.4	-0.7	-0.4	-0.4	-0.2	-0.1	0.3	0.2	2.1
Diabetes (mother)	0.2	0.2	1.2	-0.1	-0.2	-0.2	-0.5	-0.1	-0.3	0.5	0.4	0.2	0.6	0.5	0.5	0.2	-0.7	0.0	-1.1
Body mass index (BMI)	0.2	1.0	7.6	-1.7	0.5	-0.0	0.6	1.2	-0.1	1.3	0.5	1.1	0.5	0.5	0.1	-0.1	0.1	0.5	-2.8
Alcohol usually taken with meals	0.2	0.4	2.0	-0.7	-0.1	-0.1	-0.0	0.3	-0.2	0.6	0.5	0.8	0.6	0.8	0.7	-0.1	-0.2	0.6	-1.4
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	1.0	-0.7	0.7	-0.2	0.9	0.0	0.0	0.0	0.0	-0.4	-0.1	-0.2	-0.1	-1.0	0.2	-0.5	-0.2
Medication: Ramipril	0.2	0.2	0.6	-0.3	-0.6	-0.5	-0.6	-0.5	-0.6	-0.8	-0.4	-0.5	-0.3	-0.4	-0.4	-0.4	-0.6	-0.0	0.2
Impedance of arm (right)	0.2	0.9	1.7	0.9	-0.0	0.8	1.0	0.7	0.8	1.1	1.3	1.1	1.3	1.2	1.2	-0.2	0.6	1.2	-0.4
Number of live births	0.2	0.3	1.0	-0.9	-0.8	-0.5	-0.4	-0.0	-0.8	-0.2	-0.2	0.2	-0.1	0.1	-0.1	-1.0	-0.4	0.4	-0.9
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	1.3	0.2	-0.3	-0.5	-1.1	-0.6	-0.5	-1.1	-1.1	-1.0	-1.0	-0.9	-0.8	0.4	-0.5	-0.5	1.1
Noisy workplace	0.2	0.2	0.4	0.1	0.6	0.4	0.6	0.5	0.4	0.6	0.5	0.5	0.5	0.4	0.4	0.5	0.5	0.4	-0.5
Mouth/teeth dental problems: Dentures	0.2	0.3	1.7	-0.1	-0.3	0.1	-0.3	0.2	-0.1	0.7	0.4	0.8	0.5	0.6	0.4	0.4	-0.2	0.6	-1.3
Impedance of arm (left)	0.2	1.2	2.2	0.6	-0.4	0.8	1.1	0.8	0.7	1.4	1.4	1.5	1.4	1.3	1.2	-0.4	0.7	1.5	-0.9
Length of working week for main job	0.2	0.2	0.9	-0.9	-0.0	-0.4	-0.2	0.2	-0.4	0.1	-0.5	0.3	-0.5	-0.4	-0.5	-0.1	-0.1	-0.0	-0.9
Exposure to tobacco smoke at home	0.2	0.2	0.9	0.3	0.9	0.3	0.8	0.1	0.6	0.2	0.5	-0.2	0.4	0.4	0.4	-0.1	0.4	-0.5	0.7
Pulse wave reflection index	0.2	0.2	0.9	0.5	-0.6	-0.2	-1.0	-0.4	-0.3	-0.5	-0.3	-0.4	-0.1	-0.0	0.0	0.1	-0.8	0.1	0.6
Pulse wave peak to peak time	0.2	0.3	0.7	0.1	0.4	0.4	0.5	0.4	0.3	0.8	0.7	0.6	0.7	0.5	0.5	0.6	0.4	0.2	-0.8
Shortness of breath walking on level ground	0.2	0.2	1.1	-0.0	-1.1	-0.0	-0.4	0.1	-0.3	0.4	0.1	0.6	0.3	0.0	-0.0	-0.1	-0.3	0.6	-1.0
Mouth/teeth dental problems: Loose teeth	0.2	0.2	1.4	-0.3	1.2	0.1	0.8	0.6	0.4	-0.0	0.3	-0.3	0.2	0.3	0.3	-0.5	0.3	0.1	0.4
Medication for pain relief, constipation, heartburn	0.2	0.3	1.6	1.3	-0.2	0.7	0.0	-0.2	0.5	-0.1	0.2	0.2	0.3	0.2	0.4	0.4	0.6	0.4	1.1
Medication: Allopurinol	0.2	0.2	1.2	0.7	0.5	0.3	0.0	-0.2	0.3	-0.4	-0.2	-0.2	-0.3	-0.2	-0.1	1.1	0.5	-0.3	1.0
Chest pain or discomfort	0.2	0.3	1.2	-0.1	-0.8	-0.5	-1.1	-0.7	-0.6	-0.4	-0.6	-0.2	-0.4	-0.4	-0.3	0.4	-0.7	-0.2	-0.3
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	1.9	-0.9	0.1	-0.2	-0.2	0.5	-0.4	0.3	-0.3	0.4	-0.3	-0.3	-0.3	-0.1	-0.3	0.1	-1.4
Medication: Aspirin	0.2	0.2	0.8	-0.3	-0.2	-0.4	-0.2	-0.2	-0.3	0.0	-0.5	-0.5	-0.7	-0.8	-0.8	-0.2	-0.4	-0.9	-0.3
Supplements: Vitamin C	0.2	0.2	1.1	-0.0	-0.4	0.2	0.1	0.4	0.0	0.5	0.4	0.7	0.5	0.3	0.3	-0.2	0.1	0.9	-1.0
Handedness (chirality/laterality): Left-handed	0.2	0.3	1.4	1.2	0.5	0.6	0.1	0.2	0.5	0.3	0.2	0.1	0.2	0.3	0.4	1.0	0.4	-0.1	0.7
Ever had bowel cancer screening	0.2	0.2	2.1	-0.7	-0.6	-0.4	0.4	-0.2	-0.3	-0.2	-0.0	-0.3	-0.1	-0.2	-0.3	-1.4	0.0	-0.2	0.1
Diabetes diagnosed by doctor	0.2	0.3	1.0	-0.5	-1.0	-0.4	-0.4	-0.2	-0.6	0.1	-0.5	0.1	-0.5	-0.6	-0.6	-0.8	-0.3	-0.1	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.9	-0.1	-0.7	-0.4	-0.9	-0.4	-0.6	-0.3	-0.1	-0.0	0.2	0.3	0.3	0.1	-0.7	0.2	-0.4
Back pain experienced in last month	0.2	0.2	0.7	-0.2	-0.5	-0.7	-0.8	-0.9	-0.7	-0.6	-0.3	-0.5	-0.2	0.1	-0.0	0.1	-0.6	-0.5	0.1
Mineral and other dietary supplements	0.2	0.3	1.5	-0.5	-0.5	-0.5	-0.4	-0.1	-0.3	-0.5	-0.7	-0.4	-0.8	-0.7	-0.6	-1.2	-0.4	-0.0	0.2
Breast cancer (self-reported)	0.2	0.2	0.7	0.5	0.6	0.4	0.3	0.3	0.4	-0.3	-0.4	-0.1	-0.6	-0.5	-0.3	0.5	0.6	0.1	0.8
Medication: Gliclazide	0.2	0.2	0.8	-0.5	0.5	0.1	0.6	0.5	0.2	0.7	0.4	0.5	0.2	0.4	0.2	-0.0	0.3	0.1	-0.9
Miserableness	0.2	0.4	0.9	0.9	0.9	0.6	0.6	0.3	0.7	0.3	0.6	-0.1	0.7	0.6	0.7	0.6	0.5	0.0	0.9
Guilty feelings	0.2	0.4	1.4	-0.4	0.9	0.3	1.2	0.5	0.5	0.8	0.6	0.4	0.5	0.6	0.6	-0.5	0.7	-0.1	-0.5
Wears glasses or contact lenses	0.2	0.2	0.6	0.7	-0.1	0.6	0.2	0.4	0.4	0.3	0.5	0.5	0.5	0.3	0.3	0.6	0.5	0.8	0.3
Pain type(s) experienced in last month: Hip pain	0.2	0.3	0.9	-0.0	-0.8	-0.5	-0.9	-0.7	-0.7	-0.8	-0.5	-0.5	-0.4	-0.4	-0.4	0.1	-0.7	-0.1	0.3
Supplements: Fish oil (including cod liver oil)	0.2	0.2	2.1	-0.5	0.3	-0.1	0.1	0.1	-0.3	0.6	0.4	0.2	0.4	0.4	0.2	0.2	-0.3	-0.2	-1.4
Myopia	0.2	0.3	1.8	-0.2	0.2	-0.0	-0.4	0.3	-0.2	0.6	0.1	0.5	0.3	0.2	0.2	1.0	-0.5	0.1	-1.4
Pain experienced in last month	0.2	0.4	0.8	0.6	0.5	0.8	0.8	0.8	0.9	0.6	0.5	0.7	0.4	0.3	0.4	0.3	0.9	0.7	0.2
Bipolar Disorder (2018)	0.1	0.1	0.4	-0.1	0.3	0.1	0.5	0.3	0.2	-0.0	0.5	0.1	0.6	0.5	0.5	-0.3	0.0	0.6	0.0
Alzheimer’s Disease (including proxy)	0.1	0.2	0.9	-0.3	-0.9	-0.3	-0.6	-0.5	-0.5	0.0	-0.1	0.1	0.0	-0.1	-0.2	-0.1	-0.6	-0.2	-0.8
Irritable Bowel Disease (IBD)	0.1	0.3	1.6	-0.6	0.4	0.2	0.7	0.6	0.2	0.9	0.3	0.8	0.1	0.1	-0.1	0.3	0.6	-0.0	-1.3
Fasting Glucose	0.1	0.2	1.0	-0.0	-0.5	-0.3	-1.0	-0.3	-0.5	-0.1	-0.4	-0.1	-0.3	-0.2	-0.1	-0.1	-0.6	0.1	-0.4
HbA1C	0.1	0.1	0.4	0.1	-0.2	0.2	0.3	0.0	0.1	0.7	0.2	0.3	0.2	0.1	-0.1	0.2	0.2	-0.3	-0.5
Ulcerative Colitis	0.1	0.1	0.3	0.1	0.4	0.1	0.5	0.0	0.2	0.3	0.5	0.1	0.5	0.6	0.5	0.3	0.3	-0.2	-0.1
Allergy or Eczema	0.1	0.4	2.8	-1.1	0.4	-0.6	0.5	-0.3	-0.2	-0.2	0.0	-0.5	-0.0	0.0	0.1	-1.7	-0.4	-0.5	-0.4
Neuroticism	0.1	0.2	0.7	-0.4	-0.8	-0.5	-0.3	-0.6	-0.6	-0.1	-0.2	-0.1	-0.1	-0.0	-0.1	-0.8	-0.4	-0.2	-0.5
Hand grip strength (left)	0.1	0.3	1.5	0.1	1.2	0.4	0.9	0.5	0.7	0.1	0.4	-0.1	0.3	0.4	0.4	0.0	0.8	-0.1	0.9
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.6	-0.5	-0.3	0.0	0.2	0.2	-0.1	0.2	0.0	0.5	-0.0	-0.1	-0.1	-0.2	0.3	0.4	-0.8
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.5	-0.4	-0.1	-0.4	-0.1	-0.1	-0.3	0.1	-0.2	-0.3	-0.3	-0.3	-0.3	-0.6	-0.4	-0.5	-0.7
Chronic bronchitis/emphysema (father)	0.1	0.1	0.3	0.3	0.5	0.3	0.3	0.4	0.3	0.0	0.3	0.0	0.3	0.4	0.3	0.2	0.1	0.4	0.5
Financial difficulties in last 2 years	0.1	0.1	0.7	-0.9	0.1	-0.4	0.3	-0.1	-0.3	-0.1	-0.3	-0.1	-0.3	-0.2	-0.2	-0.5	0.0	-0.5	-0.3
Fluid intelligence score	0.1	0.3	0.8	0.0	-0.1	-0.5	-0.5	-0.7	-0.4	-0.7	-0.6	-0.9	-0.6	-0.6	-0.5	0.0	-0.6	-0.7	0.5
Time employed in main current job	0.1	0.1	0.3	-0.4	-0.5	-0.1	0.3	0.1	-0.0	0.4	0.1	0.5	0.0	0.1	-0.1	-0.4	0.3	0.1	-0.6
Father’s age at death	0.1	0.2	0.8	-0.1	0.7	0.0	0.3	0.1	0.1	0.8	0.3	0.1	0.3	0.4	0.4	0.2	-0.1	-0.7	-0.9
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.1	0.5	-0.2	0.2	-0.3	0.3	-0.3	-0.0	-0.1	-0.3	-0.5	-0.4	-0.5	-0.5	-0.2	-0.1	-0.7	0.2
Falls in the last year	0.1	0.1	0.4	0.6	-0.5	-0.1	-0.6	-0.1	-0.2	-0.3	-0.3	-0.2	-0.2	-0.0	-0.1	0.3	-0.2	0.3	0.6
Happiness	0.1	0.1	0.4	0.3	-0.3	-0.2	-0.5	-0.5	-0.3	-0.5	-0.3	-0.3	-0.2	-0.2	-0.1	0.6	-0.2	0.0	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.3	1.3	0.4	0.2	-0.1	-0.7	0.0	-0.1	-0.8	-0.6	-0.7	-0.6	-0.5	-0.4	0.7	-0.2	-0.0	1.1
Pulse wave Arterial Stiffness index	0.1	0.1	0.9	0.2	0.2	-0.0	-0.1	0.0	0.2	-0.4	-0.3	-0.4	-0.4	-0.2	-0.2	-0.4	-0.1	-0.0	0.9
Tense / ‘highly strung’	0.1	0.1	0.5	-0.5	-0.1	-0.3	-0.0	-0.0	-0.4	0.0	-0.3	-0.1	-0.3	-0.3	-0.3	-0.4	-0.2	-0.2	-0.7
Comparative body size at age 10	0.1	0.3	1.2	-0.6	-0.0	-0.4	-0.4	-0.5	-0.6	0.2	-0.3	-0.1	-0.2	-0.1	-0.2	0.4	-0.5	-1.0	-1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.7	0.8	0.2	0.1	-0.3	-0.5	0.0	-0.1	-0.0	-0.3	0.1	0.2	0.3	0.6	-0.1	-0.6	0.6
Migraine (self-reported)	0.1	0.1	1.0	0.1	-0.6	0.1	-0.3	-0.1	-0.2	0.5	0.1	0.6	0.2	0.1	0.1	0.3	-0.1	0.2	-1.0
Commuting to job workplace: Car/motor vehicle	0.1	0.2	0.8	0.1	0.9	0.4	0.5	0.6	0.6	0.5	0.1	0.0	0.0	-0.1	-0.1	0.5	0.3	-0.2	-0.1
Illness, injury, bereavement, stress in last 2 years	0.1	0.2	1.1	0.5	0.2	0.3	-0.4	0.2	0.1	0.2	0.3	0.3	0.4	0.4	0.4	1.1	-0.1	0.3	-0.2
Illnesses of siblings: Diabetes	0.1	0.2	1.1	-0.5	-0.2	-0.3	0.3	-0.1	-0.2	-0.4	-0.2	-0.3	-0.3	-0.5	-0.5	-1.0	-0.1	-0.1	0.1
Mood swings	0.1	0.2	0.7	0.3	0.8	0.1	0.6	0.1	0.4	0.1	-0.0	-0.3	-0.1	0.0	0.1	-0.1	0.4	-0.6	0.8
Qualifications: nursing, teaching	0.1	0.1	0.4	-0.4	-0.2	-0.2	0.3	-0.1	-0.2	-0.1	-0.3	-0.1	-0.4	-0.4	-0.4	-0.7	0.2	-0.3	-0.0
Osteoarthritis (self-reported)	0.1	0.1	0.3	-0.5	-0.3	-0.1	-0.1	0.1	-0.1	0.0	0.1	0.4	0.2	0.3	0.1	-0.1	-0.0	0.5	-0.3
Illnesses of father: None of the above (group 1)	0.1	0.1	0.3	-0.5	-0.6	-0.3	0.0	-0.3	-0.4	-0.1	-0.1	-0.0	-0.1	-0.2	-0.3	-0.5	0.0	-0.2	-0.3
Commuting to job workplace: Public transport	0.1	0.1	0.9	0.6	0.3	0.3	-0.0	0.1	0.4	-0.3	0.2	0.0	0.3	0.3	0.4	0.2	0.2	0.5	0.9
Number of operations (self-reported)	0.1	0.2	0.6	0.2	-0.3	-0.3	-0.6	-0.5	-0.4	-0.8	-0.3	-0.4	-0.1	0.0	0.0	0.2	-0.4	0.1	0.7
Commuting to job workplace: Cycle	0.1	0.1	0.5	-0.1	-0.7	-0.2	-0.6	-0.1	-0.5	0.1	0.0	0.3	0.2	0.4	0.2	0.0	-0.4	0.4	-0.6
Heart disease (siblings)	0.1	0.1	0.5	-0.4	0.1	-0.1	0.2	0.1	-0.2	0.2	0.3	0.2	0.4	0.5	0.4	-0.6	-0.2	0.1	-0.7
Neuroticism (Nagel 2018)	0.0	0.0	0.2	0.1	-0.2	-0.1	0.0	-0.2	-0.1	-0.0	0.0	-0.1	0.1	0.3	0.3	-0.4	0.1	-0.1	0.2
Ulcerative Colitis (UC)	0.0	0.0	0.1	-0.3	0.1	-0.1	0.2	-0.0	0.0	0.1	-0.0	0.0	-0.2	-0.0	-0.2	0.2	0.1	-0.3	-0.1
Ovarian Cancer	0.0	0.0	0.3	-0.0	0.4	0.1	0.0	0.2	0.1	0.2	-0.1	0.1	-0.1	-0.1	-0.1	0.6	0.1	0.1	-0.3
Hair Pigment	0.0	0.4	0.9	-0.2	0.3	0.2	0.9	-0.1	0.3	0.7	0.9	0.2	0.9	0.9	0.8	-1.0	0.4	-0.5	-0.3
Qualifications: CSEs or equivalent	0.0	0.1	0.2	0.2	-0.4	-0.2	-0.4	-0.4	-0.3	0.1	0.1	-0.1	0.2	0.2	0.1	0.3	-0.3	-0.3	-0.2
Neuroticism score	0.0	0.0	0.1	-0.0	-0.2	-0.2	-0.2	-0.1	-0.2	0.1	-0.0	-0.1	0.1	0.1	0.1	-0.3	-0.3	-0.0	-0.3
Number of full brothers	0.0	0.1	0.2	-0.3	-0.3	-0.2	-0.2	-0.2	-0.3	-0.2	-0.0	-0.1	0.1	-0.0	0.0	-0.5	-0.3	0.0	-0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.0	0.1	0.3	-0.3	-0.1	-0.3	-0.3	-0.1	-0.3	-0.2	-0.3	-0.1	-0.2	-0.1	-0.1	-0.5	-0.4	0.1	-0.3
Qualifications: College or University degree	0.0	0.1	0.9	-0.1	-0.0	0.2	0.2	0.6	0.3	-0.0	-0.2	0.4	-0.3	-0.0	0.0	-0.6	0.6	0.9	0.3

Hub : Genes

C1orf89

Models

Trait associations